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1

Cantero, Recasens Gerard 1984. "Cellular Ca2+ homeostasis in the pathophysiology of chronic respiratory diseases." Doctoral thesis, Universitat Pompeu Fabra, 2013. http://hdl.handle.net/10803/104537.

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Calcium works as a second intracellular messenger in all cell types and its downstream signalling is a key pathway for many systemic functions. In the lungs, the majority of activating stimuli trigger intracellular calcium increase, which is indispensable for the normal functioning of the airways; thus, deregulation of this pathway leads to pathological conditions. This Thesis aims to understand the relationship of intracellular calcium homeostasis and chronic respiratory pathologies such as asthma. I have studied three different processes involved in calcium homeostasis and their role i
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2

Chu, Thi Ha. "Phenotyping of chronic respiratory diseases in the South of Vietnam." Doctoral thesis, Universite Libre de Bruxelles, 2019. https://dipot.ulb.ac.be/dspace/bitstream/2013/288355/4/coverpage.pdf.

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Chronic respiratory diseases (CRDs) include chronic diseases involving the airways and other structures of the lung. In the current circumstance of Vietnam, people are exposed to numerous risk factors of CRD, such as heavy smoking, high frequency of pulmonary tuberculosis, chronic helminthiasis, allergic factors, migration and urbanization (the last associated with traffic-related pollution). The phenotype diagnoses should take into account the risk factors of each individual besides the clinical features, while the differential diagnoses mostly depend on the available techniques in each healt
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3

Baril, Jacinthe. "Interaction between circulatory and respiratory exercise adaptation in chronic obstructive pulmonary disease (COPD) and chronic heart failure (CHF)." Thesis, McGill University, 2006. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=97901.

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Chronic obstructive pulmonary disease (COPD) and chronic heart failure (CHF) patients show a marked reduction in exercise capacity compared to that of healthy age-matched individuals. While inadequate gas exchange and resulting hypoxemia appears as the primary factor in COPD, an impaired cardiac output is the predominant explanation for the reduced oxygen delivery in CHF. However, the extent of the contributions of other systemic factors remains unclear. In light of the potential interactions between cardiac output (Qc) and pulmonary hyperinflation, there is surprisingly little data thus far o
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4

Messaggi-Sartor, Monique 1984. "Respiratory muscle dysfunction in respiratory and non-respiratory diseases : clinical and therapeutic approaches." Doctoral thesis, Universitat Pompeu Fabra, 2017. http://hdl.handle.net/10803/565809.

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Respiratory muscle dysfunction is a clinical condition that may be present in both respiratory and non-respiratory diseases. This impairment of muscle function can have a negative effect on clinical outcomes, contributing to a further worsening of the patient’s clinical condition. This doctoral thesis has been directed by the ‘Rehabilitation Research Group’ (RERG) in collaboration with the Muscle Wasting and Cachexia in Chronic Respiratory Diseases and Lung Cancer Group (Lung Cancer and Muscle Research Group) of the Institut Hospital del Mar d’Investigacions Mèdiques (IMIM) in Barcelona. Muscl
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5

Koo, Sergio Don. "Quality of life in children with chronic allergic respiratory disease a population-based child health survey in Hong Kong /." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B42931538.

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6

Cook, Arlene Jane. "The role of leukotrienes in diseases causing chronic airway obstruction in children." Thesis, King's College London (University of London), 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.244248.

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7

Mazzucato, Roberta <1988&gt. "Design and Synthesis of Novel Kinase Inhibitors for the Treatment of Chronic Respiratory Diseases." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2021. http://amsdottorato.unibo.it/9617/1/Mazzucato_Roberta_Tesi.pdf.

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In 2017, Chronic Respiratory Diseases accounted for almost four million deaths worldwide. Unfortunately, current treatments are not definitive for such diseases. This unmet medical need forces the scientific community to increase efforts in the identification of new therapeutic solutions. PI3K delta plays a key role in mechanisms that promote airway chronic inflammation underlying Asthma and COPD. The first part of this project was dedicated to the identification of novel PI3K delta inhibitors. A first SAR expansion of a Hit, previously identified by a HTS campaign, was carried out. A libra
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8

Sidani, Souraya 1960. "Effects of sedative music on the respiratory status of clients with chronic obstructive airways diseases." Thesis, The University of Arizona, 1991. http://hdl.handle.net/10150/277959.

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A quasi-experimental, pre-test post-test study was conducted to examine the effects of sedative music on the perception of dyspnea intensity, respiratory rate, pulse rate and oxyhemoglobin saturation level of clients with Chronic Obstructive Airway Disease (COAD). Data was collected on a convenience sample of 10 subjects who acted as their own control. After a six minutes walk, each subject was randomly exposed to a treatment (listening to music for 20 minutes) and to a control (resting for 20 minutes) situation. A series of paired t-tests was performed to analyze the data. Results indicated t
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9

古修齊 and Sergio Don Koo. "Quality of life in children with chronic allergic respiratory disease: a population-based child health survey inHong Kong." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B42931538.

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10

Veeranki, Sreenivas P., Shimin Zheng, Yan Cao, and Arsham Alamian. "Association of Serum Vitamin D Levels with Respiratory and Atopic Diseases." Digital Commons @ East Tennessee State University, 2014. https://dc.etsu.edu/etsu-works/91.

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Background: Vitamin D is known to be associated with inflammatory diseases, but its relationship with allergic diseases is unclear. The study objective is to determine the association of serum vitamin D levels and markers of wheeze, asthma and atopy. Methods: Data (n = 9,463) on serum vitamin D levels and atopy were obtained from 2005-2006 National Health and Nutrition Examination Survey. Serum vitamin D level was categorized into four groups: Normal (≥30ng/ml), Insufficient (21-29ng/ml), Deficient (11-20ng/ml) and Severely Deficient (≤10ng/ml). Atopy was defined as at least 1 positive allerge
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11

Liu, Yi-Chia. "Understanding chronic inflammatory diseases in the human lung : the cystic fibrosis and idiopathic pulmonary fibrosis paradigms." Thesis, University of Nottingham, 2014. http://eprints.nottingham.ac.uk/27807/.

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The chronic infection of the cystic fibrosis (CF) lung with Pseudomonas aeruginosa strongly correlates with critical outcomes. Pseudomonas alkyl-quinolone signal (PQS) is a diffusible cell-density dependent signal controlling the production of virulence determinants. The PQS amount in the CF lung was proportionate to P. aeruginosa colonisation and PQS molecules have been demonstrated to inhibit pro-inflammatory signalling. However, how PQS influence the recognition of P. aeruginosa by the human lung is unknown. The contribution of PQS to the interaction of P. aeruginosa with human bronchial ep
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12

ZHOU, TINGYANG ZHOU. "Molecular Roles of ROS in Mouse Respiratory Skeletal Muscle." The Ohio State University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=osu1531848449464785.

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13

Jónsson, Baldvin. "Chronic lung disease of prematurity : a study of selected causative factors and preventive measures /." Stockholm, 1998. http://diss.kib.ki.se/1998/19981204jons/.

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14

Velickovski, Filip. "Clinical decision support for screening, diagnosis and assessment of respiratory diseases: chronic obstructive pulmonary disease as a use case." Doctoral thesis, Universitat de Girona, 2016. http://hdl.handle.net/10803/457000.

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In this thesis we propose a framework for designing, developing, a clinical decision support systems (CDSS) offering a suite of services for the early detection and assessment of chronic obstructive pulmonary disease (COPD), and then demonstrate how these services can be integrated into the work-flow of healthcare providers. Furthermore, we focus on supporting spirometry, one of the main diagnostic tools in respiratory disease assessment. We present two methods to offer decision support in assuring the quality of a spirometry test that can be easily embedded into the CDSS framework. The first
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15

Härter, Martin, Harald Baumeister, Katrin Reuter, et al. "Increased 12-Month Prevalence Rates of Mental Disorders in Patients with Chronic Somatic Diseases." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2012. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-100021.

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Background: Although it is well established that chronic somatic diseases are significantly associated with a wide range of psychopathology, it remains unclear to what extent subjects with chronic somatic diseases are at increased risk of experiencing mental disorders. The present epidemiological study investigates age- and sex-adjusted 12-month prevalence rates of mental disorders in patients with cancer, and musculoskeletal, cardiovascular and respiratory tract diseases, based on comprehensive physicians’ diagnoses and compared with physically healthy probands. Methods: Prevalence rates wer
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Willson, Grant Neville. "Nocturnal non-invasive ventilation for the treatment of Cheyne-Stokes respiration in chronic heart failure." Thesis, The University of Sydney, 2004. https://hdl.handle.net/2123/27912.

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This thesis has investigated the efficacy of non-invasive ventilation in subjects with congestive heart failure (CHF) and Cheyne—Stokes respiration (CSR). The effect of this therapy on sleep, breathing and haemodynamic variables has been examined. This thesis also describes the morphology and magnitude of the blood pressure (BP) and heart rate (HR) oscillations associated with CSR and elucidates contributing factors to the changes observed. Chapter 1 - literature review - outlines the presentation and treatment of CSR in patients with CHF. Cheyne-Stokes respiration is described with p
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Härter, Martin, Harald Baumeister, Katrin Reuter, et al. "Increased 12-Month Prevalence Rates of Mental Disorders in Patients with Chronic Somatic Diseases." Karger, 2007. https://tud.qucosa.de/id/qucosa%3A26278.

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Background: Although it is well established that chronic somatic diseases are significantly associated with a wide range of psychopathology, it remains unclear to what extent subjects with chronic somatic diseases are at increased risk of experiencing mental disorders. The present epidemiological study investigates age- and sex-adjusted 12-month prevalence rates of mental disorders in patients with cancer, and musculoskeletal, cardiovascular and respiratory tract diseases, based on comprehensive physicians’ diagnoses and compared with physically healthy probands. Methods: Prevalence rates wer
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18

Meren, Mari. "Asthma, chronic bronchitis, chronic obstructive pulmonary disease (COPD) and respiratory symptoms among adults in Estonia: prevalence and risk factors - comparison with Sweden and Finalnd : the "FinEsS" studies - Estonia I /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-537-2/.

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19

Carandina, Luana. "Prevalência de sintomas sugestivos de doenças respiratórias crônicas inespecíficas na população urbana de Botucatu, São Paulo." Universidade de São Paulo, 1987. http://www.teses.usp.br/teses/disponiveis/6/6132/tde-18102017-184820/.

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Em uma amostra de 12 por cento da população urbana de Botucatu, São Paulo, constituída de 7.075 pessoas, foram identificados 525 indivíduos com sintomas sugestivos de doença respiratória crônica inespecífica (DRCI). Utilizando o questionário de sintomas respiratórios \"ATS-DLD-78\", aplicado por entrevistadores leigos, a autora determinou a prevalência de alguns sintomas e de associações sugestivas de asma brônquica, bronquite crônica e doença pulmonar obstrutiva crônica (DPOC). Os sintomas mais frequentes no sexo masculino, foram: tosse, expectoração e chiado, cuja prevalência foi de 6,2 por
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20

Törneke, Karolina. "Pharmacological aspects of adrenoceptor drugs in the horse /." Uppsala : Swedish Univ. of Agricultural Sciences (Sveriges lantbruksuniv.), 1999. http://epsilon.slu.se/avh/1999/91-576-5431-X.pdf.

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21

Eyong, Ayuk. "Mediating factors in the relationship between sociodemographic factors and Chronic Lower Respiratory Diseases (CLRD) among adult ACBS respondents in the United States." Thesis, Lancaster University, 2018. http://eprints.lancs.ac.uk/126217/.

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Background: Chronic Lower Respiratory Diseases (CLRD), such as asthma, chronic obstructive pulmonary disease (COPD), chronic bronchitis and emphysema are preventable diseases that constitute a serious public health concern. Estimates indicate that there is an increased prevalence of mortality from these diseases worldwide. Low socio-economic positions (SEP) and poor indoor environmental conditions have been identified as risk factors for CLRD among adults. Given the public health burden of CLRD, there is increasing interest among researchers to identify all relevant factors associated with CLR
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22

Shim, Joanna. "Symptomatic diagnosis of lung cancer in a population referred to lung-shadow clinic with high rates of chronic respiratory diseases : a feasibility study." Thesis, University of Southampton, 2015. https://eprints.soton.ac.uk/384345/.

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n the UK, 86% of lung cancer (LC) patients are diagnosed when curative treatment is not possible. Government guidelines recommend urgent chest X-ray referrals for patients presented with any 1 of 10 suggested LC symptoms. Little evidence currently supports these recommendations. Thus, the need for prospective studies to identify the predictive values of symptoms for LC diagnosis. This study aimed to investigate the feasibility of a prospective study to identify symptoms that predict LC in a secondary care population with high rates of chronic respiratory disease by investigating 1) the content
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23

Корнус, Олеся Григорівна, Olesia Hryhorivna Kornus, Анатолій Олександрович Корнус та ін. "Територіальні відмінності захворюваності населення Сумської області на хронічні обструктивні захворювання легень". Sp. z o.o. «Diamond trading tour», 2019. http://repository.sspu.sumy.ua/handle/123456789/7304.

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Спостереженням охоплено період 2005–2017 років. Станом на 1.01.2018 р. у Сумській області первинна захворюваність на хвороби органів дихання становила 22 070,29 на 100 тис. осіб, а поширеність хвороб – 28 054,31 випадків на 100  тис. населення. Протягом 2005-2017  років спостерігається зростання як первинної захворюваності (на 15,04 %), так і поширеності хвороб органів дихання – на 14,42 %.<br>The observation covers the period 2005-2017. As of January 1, 2018, in the Sumy region, the primary incidence of respiratory diseases was 22,070.29 per 100 thousand people, and the prevalence of diseases
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24

Faganello, Marcia Maria. "Fatores associados à ocorrência de exacerbação em pacientes com DPOC /." Botucatu : [s.n.], 2007. http://hdl.handle.net/11449/102611.

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Orientador: Irma de Godoy<br>Banca: Hugo Hyung Bok Yoo<br>Banca: Fabio de Oliveira Pitta<br>Banca: Maria Christina L. O. Machado<br>Banca: Alberto Cukier<br>Resumo: Nos últimos anos, vários estudos avaliaram os marcadores da doença associados à freqüência de exacerbação, hospitalização, readmissão e mortalidade em pacientes portadores de doença pulmonar obstrutiva crônica (DPOC). Entretanto, estudos que avaliaram os marcadores associados à ocorrência de exacerbação em pacientes ambulatoriais são limitados. Assim, o objetivo deste estudo foi identificar os fatores de predição da ocorrência de e
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25

Bugajski, Andrew A. "BIOLOGICAL, BEHAVIORAL, AND PSYCHOSOCIAL ATTRIBUTES OF INDIVIDUALS WITH COPD." UKnowledge, 2018. https://uknowledge.uky.edu/nursing_etds/36.

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The purpose of this dissertation was to evaluate the biological, behavioral, and psychosocial attributes of individuals diagnosed with chronic obstructive pulmonary disease (COPD). Specific aims were to: 1) explore the predictive power of spirometry measures for event-free survival in patients with heart failure and suspected COPD, focusing on the differences in survival between those with and without airflow limitation; 2) examine the psychometric properties of the Multidimensional Scale of Perceived Social Support (MSPSS) in patients with concomitant COPD and heart failure; and 3) test the e
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Wang, Ke-Sheng, Liang Wang, Shimin Zheng, and Long-Yang Wu. "Associations of Smoking Status and Serious Psychological Distress with Chronic Obstructive Pulmonary Disease." Digital Commons @ East Tennessee State University, 2013. https://dc.etsu.edu/etsu-works/39.

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Background: Chronic obstructive pulmonary disease (COPD) has been a major public health problem due to its high prevalence, morbidity, and mortality. Smoking is a major risk factor for COPD, while serious psychological distress (SPD) is prevalent among COPD patients. However, no study focusing on the effect of SPD on COPD has been so far conducted, while few studies have focused on the associations of SPD and behavioral factors with COPD by smoking status. Objectives: This study aimed to examine the associations of SPD and behavioral factors (such as smoking and physical activity) with COPD. M
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27

Chacko, Anu. "Comparison of human and animal Chlamydia pneumoniae responses to interferon gamma and penicillin treatment." Thesis, Queensland University of Technology, 2015. https://eprints.qut.edu.au/85438/1/Anu_Chacko_Thesis.pdf.

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This thesis has made a significant contribution to future chlamydial research by uncovering the chlamydial pathogenic mechanisms which will potentially help in the development of targeted vaccine against the pathogen. This thesis has made important new contributions to our understanding of Chlamydia pneumoniae specific adaptations to stress responses and has provided new perspectives on the survival of this successful pathogen. This thesis has used two well established microbial stressors and has identified major differences in stress responses between human and animal Chlamydia pneumoniae iso
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Alibakhshi, Esmaeil. "Femoral bone mineral density and rectus femoris phenotype as sarcopenia indicators after a pulmonary rehabilitation protocol in patients with chronic respiratory disease." Doctoral thesis, Universitat de Barcelona, 2019. http://hdl.handle.net/10803/668651.

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INTRODUCTION: Patients with chronic respiratory disease (CRDs) have a disorder in muscle structure and function, but their function increases with physical progress and decreases the risk of general and muscular weakness. CRDs patients with muscle weakness also have higher mortality rates than patients without muscle weakness and they are more likely to develop sarcopenia and the incidence of pathogens. The Main objective of the present study was to evaluate the indicators of Sarcopenia in chronic respiratory patients with a greater focus on musculoskeletal structure and function and quality o
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29

Faganello, Marcia Maria [UNESP]. "Fatores associados à ocorrência de exacerbação em pacientes com DPOC." Universidade Estadual Paulista (UNESP), 2007. http://hdl.handle.net/11449/102611.

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Made available in DSpace on 2014-06-11T19:32:12Z (GMT). No. of bitstreams: 0 Previous issue date: 2007-03-16Bitstream added on 2014-06-13T20:42:56Z : No. of bitstreams: 1 faganello_mm_dr_botfm.pdf: 465819 bytes, checksum: 7899369510ab22be938ad270a777ebd2 (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>Nos últimos anos, vários estudos avaliaram os marcadores da doença associados à freqüência de exacerbação, hospitalização, readmissão e mortalidade em pacientes portadores de doença pulmonar obstrutiva crônica (DPOC). Entretanto, estudos que avaliaram os marcador
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30

Chin, Elizabeth D. "Symptom Experience and Treatment Delay during Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Dissertation." eScholarship@UMMS, 2012. https://escholarship.umassmed.edu/gsn_diss/30.

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Chronic obstructive pulmonary disease (COPD) is a major health problem in the United States. Acute exacerbations of COPD are primarily responsible for the physical, psychological and economic burden of this disease. Early identification and treatment of exacerbations is important to improve patient and healthcare outcomes. Little is known about how patients with COPD recognize an impending exacerbation and subsequently decide to seek treatment. The purpose of this qualitative descriptive study was to explore and describe symptom recognition and treatment delay in individuals experiencing an ac
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31

French, Cynthia L. "Examining Change in Symptoms of Depression, Anxiety, and Stress in Adults after Treatment of Chronic Cough: A Dissertation." eScholarship@UMMS, 2014. https://escholarship.umassmed.edu/gsn_diss/31.

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Background: Chronic cough is a common health problem with variable success rates to standardized treatment. Psychologic symptoms of depression, anxiety, and stress have been reported in association with chronic cough. The purpose of this study was to examine changes in the psychologic symptoms of depression, anxiety, and stress in adults with chronic cough 3 months after management using the ACCP cough treatment guidelines. Methods: This study used a descriptive longitudinal observation design. The major tenets associated with the Theory of Unpleasant Symptoms were examined. Intervention fidel
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32

Roos-Engstrand, Ester. "T cells in chronic obstructive pulmonary disease." Doctoral thesis, Umeå : Umeå university, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-33677.

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33

Корнус, Олеся Григорівна, Олеся Григорьевна Корнус, Olesia Hryhorivna Kornus та ін. "Територіальні відмінності захворюваності населення Сумської області на хронічні обструктивні захворювання легень". Thesis, "Diamond trading tour", 2019. http://essuir.sumdu.edu.ua/handle/123456789/72895.

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Спостереженням охоплено період 2005–2017 років. Станом на 1.01.2018 р. у Сумській області первинна захворюваність на хвороби органів дихання становила 22 070,29 на 100 тис. осіб, а поширеність хвороб – 28 054,31 випадків на 100  тис. населення. Протягом 2005-2017  років спостерігається зростання як первинної захворюваності (на 15,04 %), так і поширеності хвороб органів дихання – на 14,42 %.<br>Наблюдением охвачен период 2005-2017 годов. По состоянию на 1.01.2018 г. в Сумской области первичная заболеваемость болезнями органов дыхания составила 22 070,29 на 100 тыс. человек, а распространенность
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34

Fisher, Kimberly A. "Impact of COPD on the Mortality and Treatment of Patients Hospitalized with Acute Decompensated Heart Failure (The Worcester Heart Failure Study): A Masters Thesis." eScholarship@UMMS, 2014. https://escholarship.umassmed.edu/gsbs_diss/717.

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Objective: Chronic obstructive pulmonary disease (COPD) is a common comorbidity in patients with heart failure, yet little is known about the impact of this condition in patients with acute decompensated heart failure (ADHF), especially from a more generalizable, community-based perspective. The primary objective of this study was to describe the in-hospital and post discharge mortality and treatment of patients hospitalized with ADHF according to COPD status. Methods: The study population consisted of patients hospitalized with ADHF at all 11 medical centers in central Massachusetts during 4
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Fisher, Kimberly A. "Impact of COPD on the Mortality and Treatment of Patients Hospitalized with Acute Decompensated Heart Failure (The Worcester Heart Failure Study): A Masters Thesis." eScholarship@UMMS, 2007. http://escholarship.umassmed.edu/gsbs_diss/717.

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Objective: Chronic obstructive pulmonary disease (COPD) is a common comorbidity in patients with heart failure, yet little is known about the impact of this condition in patients with acute decompensated heart failure (ADHF), especially from a more generalizable, community-based perspective. The primary objective of this study was to describe the in-hospital and post discharge mortality and treatment of patients hospitalized with ADHF according to COPD status. Methods: The study population consisted of patients hospitalized with ADHF at all 11 medical centers in central Massachusetts during 4
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Flaherty, Helen M. "Informal Caregivers’ Experience During Acute Exacerbation of COPD in Older Adults: A Dissertation." eScholarship@UMMS, 2017. https://escholarship.umassmed.edu/gsn_diss/51.

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Chronic obstructive pulmonary disease (COPD) has been recognized as a leading cause of mortality in older adults involving acute exacerbations as life-threatening events that lead to frequent hospitalization for care. Informal caregivers have been essential to helping older adults with COPD during an acute exacerbation of chronic obstructive pulmonary disease (AECOPD). A lack of empirical knowledge exists regarding the experience of informal caregivers of older adults with AECOPD in situation awareness for recognizing, understanding, and responding to an AECOPD in an emergent situation. This q
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Costa, Gerusa Maritimo da. "Efeito do uso de salbutamol nas propriedades mecânicas do sistema respiratório de indivíduos saudáveis, tabagistas e portadores de doença pulmonar obstrutiva crônica." Universidade do Estado do Rio de Janeiro, 2012. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=6359.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>A doença pulmonar obstrução crônica (DPOC) é caracterizada pela limitação de fluxo parcialmente reversível, classificada por níveis de obstrução pós-broncodilatador. Há várias evidências de que o FEV1 sozinho não é capaz de mostrar a broncodilatação de pacientes com DPOC, mesmo naqueles que apresentam melhora clínica. A técnica de oscilações forçadas (TOF) tem mostrado alta sensibilidade na detecção precoce de alterações mecânicas na DPOC, contudo o efeito broncodilatador na impedância respiratória de pacientes com DPOC ainda não e
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Mentro, Anne M. "Vitamin A status and inflammation during the first week of life in extremely premature infants at risk for bronchopulmonary dysplasia." Connect to this title online, 2004. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1092500146.

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Thesis (Ph. D.)--Ohio State University, 2004.<br>Title from first page of PDF file. Document formatted into pages; contains xiv, 133 p.; also includes graphics (some col.) Includes bibliographical references (p. 107-133). Available online via OhioLINK's ETD Center
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Günther, Sven. "Remodelage vasculaire pulmonaire associé à la fibrose pulmonaire : implication de l'axe MIF-CD74 A role of MIF and D-DT in immune-inflammatory, autoimmune, and chronic respiratory diseases: from pathogenic factors to therapeutic targets MIF inhibition in a murine model of bleomycin-induced pulmonary fibrosis." Thesis, Sorbonne Paris Cité, 2018. https://wo.app.u-paris.fr/cgi-bin/WebObjects/TheseWeb.woa/wa/show?t=2253&f=14280.

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Des travaux récents ont mis en évidence une surexpression du facteur MIF (facteur inhibiteur de la migration des macrophages), un des plus anciens médiateurs immunologiques connus, et de son récepteur CD74 dans l'hypertension pulmonaire idiopathique. Or, la sur-activation de cet axe MIF-CD74 est connue pour contribuer à l'acquisition et au maintien d'un phénotype pro-inflammatoire de la cellule endothéliale pulmonaire (Le Hiress et al. 2015). Les taux sériques élevés de MIF ont été mis en évidence dans de nombreuses pathologies respiratoires chroniques, notamment dans la fibrose pulmonaire idi
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Domínguez, Fandos David. "Estudio de los efectos de agentes anticolinérgicos y de inhibidores de fosfodiesterasa-5 sobre la estructura pulmonar en un modelo experimental de enfermedad pulmonar obstructiva crónica inducido por humo de tabaco en el cobayo." Doctoral thesis, Universitat de Barcelona, 2015. http://hdl.handle.net/10803/293379.

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La enfermedad pulmonar obstructiva crónica (EPOC) es una patología prevenible caracterizada por una limitación al flujo aéreo progresiva y no completamente reversible, disnea, producción de esputo y tos crónica. La obstrucción al flujo aéreo se asocia a un proceso inflamatorio crónico en la vía aérea y el parénquima pulmonar en respuesta a partículas nocivas o gases inhalados, en particular al humo de cigarrillo (HC) (Figura. Esta respuesta inflamatoria crónica puede inducir la destrucción del parénquima pulmonar o enfisema y alteraciones estructurales de la vía aérea pequeña al alterar los
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Balasubramanian, Deepak. "Pseudomonas Aeruginosa AmpR Transcriptional Regulatory Network." FIU Digital Commons, 2013. http://digitalcommons.fiu.edu/etd/863.

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In Enterobacteriaceae, the transcriptional regulator AmpR, a member of the LysR family, regulates the expression of a chromosomal β-lactamase AmpC. The regulatory repertoire of AmpR is broader in Pseudomonas aeruginosa, an opportunistic pathogen responsible for numerous acute and chronic infections including cystic fibrosis. Previous studies showed that in addition to regulating ampC, P. aeruginosa AmpR regulates the sigma factor AlgT/U and production of some quorum sensing (QS)-regulated virulence factors. In order to better understand the ampR regulon, the transcriptional profiles generated
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Salomão, Junior João Batista. "Competência social e transtornos comportamentais em crianças portadoras de asma moderada e grave." Faculdade de Medicina de São José do Rio Preto, 2001. http://bdtd.famerp.br/handle/tede/154.

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Made available in DSpace on 2016-01-26T12:51:40Z (GMT). No. of bitstreams: 1 joabatistasalomao_dissert.pdf: 485965 bytes, checksum: a1e9ad096dff68d92c37d5033056c5f6 (MD5) Previous issue date: 2001-06-12<br>Objective Evaluate, social competence and behavior disorders in children with moderate to severe asthma according to parental perception. Casuistics: Sixty-two patients were studied, 36 male and 26 female, ages ranging from 7 to 16 years (MA: 10.94; SD: 2.28), with clinical diagnosis of moderate to severe asthma, without comorbidity, seen at the Pediatric Pneumology Service and the Aller
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mattioli. "Dietary flavonoids and chronic respiratory diseases in Italian adults." Doctoral thesis, 2020. http://hdl.handle.net/11562/1018846.

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Introduzione e obiettivi: I flavonoidi sono bio-composti presenti in quantità consistenti in alcuni tipi di frutta, verdura, erbe e vino rosso. Grazie al loro effetto antiossidante e antinfiammatorio sulle vie aeree, è stato ipotizzato che i flavonoidi possano ridurre la gravità e/o prevenire il rischio di malattie polmonari. Lo scopo di questa tesi è stimare l’associazione tra asma (corrente e in passato), bronchite cronica, rinite (allergica e non) e assunzione di flavonoidi con la dieta (flavonoidi totali e sottoclassi principali: flavanoni, antociani, flavan-3-oli, flavonoli, flavoni, poli
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Alemayohu, Mulubirhan Assefa. "Dietary Flavonoids and Respiratory Outcomes: Evidence from the BOLD Study." Doctoral thesis, 2022. http://hdl.handle.net/11562/1073517.

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Il peso della broncopneumopatia cronica ostruttiva (BPCO) è cresciuto drammaticamente ed è ora la terza causa di morte, con quasi dieci anni di anticipo rispetto all'anno previsto dall'Organizzazione Mondiale della Sanità (OMS). La BPCO è stata riconosciuta essere un killer silenzioso nei Paesi a basso e medio reddito, dove si verificano 9 decessi su 10 per BPCO. I progressi in campo medico compiuti negli ultimi decenni non sono stati sufficienti e, per ottenere una riduzione significativa dei tassi di incidenza, è necessario un nuovo paradigma incentrato sulla salute pubblica e sugli stili di
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Nguyen, Tu Son. "Promoting quality use of medicine in chronic respiratory diseases in Vietnam: the role of pharmacists." Thesis, 2019. http://hdl.handle.net/1959.13/1404547.

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Research Doctorate - Doctor of Philosophy (PhD)<br>Nowadays, the role of pharmacists has evolved to become health care providers of pharmaceutical care services that incorporates patient-orientated and product-orientated services. They not only work together with other health care providers, but also with patients in order to achieve positive outcomes for their therapeutic management. However, in Vietnam and other developing countries, both community and hospital pharmacists are still substantially under-utilised for patient care compared against the pharmaceutical care model of practice. How
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Govender, Nadira. "Occupational exposures and chronic obstructive pulmonary disease : a hospital-based case-control study." Thesis, 2009. http://hdl.handle.net/10413/4793.

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Aim The aim of this study was to determine the contribution of occupational exposures to the burden of Chronic Obstructive Pulmonary Disease (COPD) among a sample of hospital based patients. Methods Cases (n=110) with specialist physician diagnosed COPD from the three public sector specialist respiratory clinics in KZN and controls (n=102) from other nonrespiratory chronic ailment specialist clinics at the same institutions were selected. An interviewer administered questionnaire and exposure history was obtained for each participant. In addition, a valid lung function test was obtained for ea
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Almojaibel, Abdullah. "Understanding intention to use telerehabilitation : applicability of the Technology Acceptance Model (TAM)." Diss., 2017. http://hdl.handle.net/1805/14970.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>Background: Pulmonary rehabilitation (PR) has the potential to reduce the symptoms and complications of respiratory diseases through an interdisciplinary approach. Providing PR services to the increasing number of patients with chronic respiratory diseases challenges the current health care systems because of the shortages in health care practitioners and PR programs. Using telerehabilitation may improve patients’ participation and compliance with PR programs. The purpose of this study was to examine the applicability of
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Portas, Laura. "The socio-economic cost of asthma, COPD and chronic bronchitis in Europe." Doctoral thesis, 2019. http://hdl.handle.net/11562/995244.

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Introduction. Common chronic respiratory diseases place a huge economic burden on both society and individual but very few COI studies have been carried out in the general European population and have evaluated (i) both direct and indirect costs, (ii) the change over time in asthma costs, (iii) the relationship with the level of asthma severity and control, and (iv) the presence of comorbidities in chronic bronchitis (CB). Aims. This thesis is aimed at estimating (i) the differential costs of asthma, COPD and CB among adult subjects from the general population in Europe and (ii) the 10-year v
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Омельченко, Світлана Анатоліївна. "Ефективність гімнастики Цигун в комплексній реабілітації осіб з хронічними обструктивними захворюваннями легень". Магістерська робота, 2020. https://dspace.znu.edu.ua/jspui/handle/12345/4549.

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Омельченко С. А. Ефективність гімнастики Цигун в комплексній реабілітації осіб з хронічними обструктивними захворюваннями легень : кваліфікаційна робота магістра спеціальності 227 «Фізична терапія, ерготерапія» / наук. керівник І. В. Кальонова. Запоріжжя : ЗНУ, 2020. 60 с.<br>UA : Дипломна робота: 60 сторінок, 4 таблиці, 10 рисунків, 54 літературних джерела. Об’єкт дослідження – Цигун терапія у легеневій реабілітації хворих на хронічні обструктивні захворювання легень. Мета дослідження – оцінка ефективності застосування гімнастики Цигун в комплексній реабілітації хворих на хронічні обструкти
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Cravidão, Rita Almeida Carreiras da Fonseca. "Acompanhamento farmacêutico da DPOC na farmácia comunitária." Master's thesis, 2017. http://hdl.handle.net/10437/8314.

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Orientação: Madalena Pereira<br>A DPOC assume nos dias de hoje particular relevância nas sociedades mais desenvolvidas. É uma doença subdiagnosticada, representando uma das principais causas de morbilidade e mortalidade quer em Portugal, quer a nível internacional, prevendo-se o aumento da sua prevalência nos próximos anos. Assim, o aumento desta patologia conduz a uma preocupação crescente no que respeita à sua prevenção e controlo, sendo objeto de estudo neste trabalho. Desta forma, procedeu-se à elaboração de um fluxograma de orientação farmacêutica na DPOC para que possa ser aplicado em
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