Academic literature on the topic 'Floating Tablet A Gastro'

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Journal articles on the topic "Floating Tablet A Gastro"

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Niranjan, Abadhesh Kumar, and Aditya Kumar. "Development and Evaluation of Gastro Retentive Floating Drug Delivery System of Ondansetron Hydrochloride." Journal of Drug Delivery and Therapeutics 11, no. 6 (2021): 150–58. http://dx.doi.org/10.22270/jddt.v11i6.5084.

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The Aim of the present study was to develop & evaluate Gastro-retentive floating Tablet of Ondansetron hydrochloride. The Objective was to calibrate and validate the UV- spectroscopy analytical method and to prepare and optimize the GR Floating tablets of Ondansetron hydrochloride in terms of dissolution release profile. The FDDS of the drug can minimize the fluctuation of drug plasma levels and result to associated adverse reactions, dosing frequency, and improved patient compliance. Conventionally, Ondansetron hydrochloride is taken up 2-3 times daily in the treatment of nausea and vomit
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Vaishnav, Parul, Kuldeep Vinchurkar, and Dinesh K. Mishra. "DESIGN AND DEVELOPMENT OF GASTRO-RETENTIVE FLOATING TABLET CASE USING FDM 3D PRINTING TECHNOLOGY." INDIAN DRUGS 61, no. 08 (2024): 44–53. http://dx.doi.org/10.53879/id.61.08.14554.

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The aim of this research was to examine a novel Fused Deposition Model (FDM) 3D Printing Method for creating a gastro-retentive floating tablet case containing metronidazole compressed tablet. Metronidazole was employed as a model drug and successfully integrated into floating tablet case composed of polyvinyl alcohol filament. The tablet design was made by AutoCAD software and the slicing of tablet design was carried out. To evaluate the formulation parameters for 3D printed tablet case, various orifice sizes were optimized. These 3D printed tablet cases were assessed for weight variation, fr
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Kapil, Jalodiya, Jain Sourabh, and Shukla Karunakar. "Formulation and evaluation of gastro-retentive floating tablets of terbinafine." GSC Biological and Pharmaceutical Sciences 13, no. 1 (2020): 257–66. https://doi.org/10.5281/zenodo.4264695.

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Gastro-retentive dosage forms enable prolonged and continuous input of the drug to the upper parts of the gastrointestinal tract and improve the bioavailability of medications those are characterized by a narrow absorption window. The purpose of this research was to develop a novel gastro retentive drug delivery system based on direct compression method for sustained delivery of active agent to improve the bioavailability, reduce the number of doses and to increase patient compliance. Gastro retentive floating tablets of terbinafine were prepared by direct compression method using altered conc
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Thapa, Prakash, and Seong Jeong. "Effects of Formulation and Process Variables on Gastroretentive Floating Tablets with A High-Dose Soluble Drug and Experimental Design Approach." Pharmaceutics 10, no. 3 (2018): 161. http://dx.doi.org/10.3390/pharmaceutics10030161.

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To develop sustained release gastro-retentive effervescent floating tablets (EFT), a quality-based experimental design approach was utilized during the composing of a hydrophilic matrix loaded with a high amount of a highly water-soluble model drug, metformin HCl. Effects of the amount of polyethylene oxide WSR 303 (PEO), sodium bicarbonate, and tablet compression force were used as independent variables. Various times required to release the drug, tablet tensile strength, floating lag time, tablet ejection force, and tablet porosity, were selected as the responses. Polymer screening showed th
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Patle, Bharti, Vivek Jain, Shradha Shende, and Prabhat Kumar Jain. "Formulation Development and Evaluation of Sustain Release Gastroretentive Floating Tablets of Prochlorperazine Dimaleate." Journal of Drug Delivery and Therapeutics 9, no. 4-s (2019): 445–50. http://dx.doi.org/10.22270/jddt.v9i4-s.3353.

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Floating drug delivery systems are the gastroretentive forms that precisely control the release rate of target drug to a specific site which facilitate an enormous impact on health care. The purpose of this research was to develop a novel gastro retentive drug delivery system based on direct compression method for sustained delivery of active agent to improve the bioavailability, reduce the number of doses and to increase patient compliance. Gastro retentive floating tablets of Prochlorperazine dimaleate (PCZ) were prepared by direct compression method using altered concentrations of HPMC K4,
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Kam, Li-Ying, Jia-Woei Wong, and Kah-Hay Yuen. "In Vivo Evaluation of Thiamine Hydrochloride with Gastro-Retentive Drug Delivery in Healthy Human Volunteers Using Gamma Scintigraphy." Pharmaceutics 15, no. 2 (2023): 691. http://dx.doi.org/10.3390/pharmaceutics15020691.

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A floating tablet system containing thiamine hydrochloride, a model drug with a narrow absorption window, was evaluated. The tablet was found to have a floating lag time of less than 30 s with a sustained drug release over 12 h during in vitro dissolution studies. The gastro-retentive property of the tablet in relation to the bioavailability of thiamine was determined in healthy human volunteers using gamma scintigraphy under fasted and fed conditions. The gastro-retentive time of the floating tablet could be prolonged up to 10 h under the fed state, compared to about 1.8 h in the fasted state
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Rajni, Jain Poorva Jain Sourabh Jain and Aakanchha Jain*. "ANTIHYPERLIPIDIMIC GASTRO FLOATING TABLET OF PRAVASTATIN PREPARED FROM DIFFERENT GRADES OF HPMC POLYMER." IAJPS,CSK PUBLICATIONS 03, no. 10 (2016): 1139–46. https://doi.org/10.5281/zenodo.164195.

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Oral route is the most convenient route for the drug delivery because of ease of administration, economic therapy & patient compliance. Floating drug delivery system (FDDS) is one of the convenient ways than the convectional oral drug administration which keep drugs buoyant is stomach due to their low density than gastric fluid and can be a potential candidate for controlled release of drug over an extended period of time. FDDS are expected to maximize the absorption resulting in enhanced bioavailability and prolong residence time of drug in stomach. Pravastatin is an oral hyperlipidemic d
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Rajni, Jain Poorva Jain Sourabh Jain and Aakanchha Jain. "ANTIHYPERLIPIDIMIC GASTRO FLOATING TABLET OF PRAVASTATIN PREPARED FROM DIFFERENT GRADES OF HPMC POLYMER." IAJPS,CSK PUBLICATIONS 03, no. 10 (2016): 1139–46. https://doi.org/10.5281/zenodo.164196.

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Oral route is the most convenient route for the drug delivery because of ease of administration, economic therapy & patient compliance. Floating drug delivery system (FDDS) is one of the convenient ways than the convectional oral drug administration which keep drugs buoyant is stomach due to their low density than gastric fluid and can be a potential candidate for controlled release of drug over an extended period of time. FDDS are expected to maximize the absorption resulting in enhanced bioavailability and prolong residence time of drug in stomach. Pravastatin is an oral hyperlipidemic d
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Rajni, Jain Poorva Jain Sourabh Jain and Aakanchha Jain. "ANTIHYPERLIPIDIMIC GASTRO FLOATING TABLET OF PRAVASTATIN PREPARED FROM DIFFERENT GRADES OF HPMC POLYMER." IAJPS,CSK PUBLICATIONS 03, no. 10 (2016): 1139–46. https://doi.org/10.5281/zenodo.164217.

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Oral route is the most convenient route for the drug delivery because of ease of administration, economic therapy & patient compliance. Floating drug delivery system (FDDS) is one of the convenient ways than the convectional oral drug administration which keep drugs buoyant is stomach due to their low density than gastric fluid and can be a potential candidate for controlled release of drug over an extended period of time. FDDS are expected to maximize the absorption resulting in enhanced bioavailability and prolong residence time of drug in stomach. Pravastatin is an oral hyperlipidemic d
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Kapil Jalodiya, Sourabh Jain, and Karunakar Shukla. "Formulation and evaluation of gastro-retentive floating tablets of terbinafine." GSC Biological and Pharmaceutical Sciences 13, no. 1 (2020): 257–66. http://dx.doi.org/10.30574/gscbps.2020.13.1.0310.

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Gastro-retentive dosage forms enable prolonged and continuous input of the drug to the upper parts of the gastrointestinal tract and improve the bioavailability of medications those are characterized by a narrow absorption window. The purpose of this research was to develop a novel gastro retentive drug delivery system based on direct compression method for sustained delivery of active agent to improve the bioavailability, reduce the number of doses and to increase patient compliance. Gastro retentive floating tablets of terbinafine were prepared by direct compression method using altered conc
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Dissertations / Theses on the topic "Floating Tablet A Gastro"

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Chanyandura, Jonathan Tinotenda. "Formulation and evaluation of castro-retentive floating tablet of griseofulvin." Thesis, 2018. http://hdl.handle.net/10386/2228.

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Thesis (M.Pharm. (Pharmaceutics) -- University of Limpopo, 2018<br>Griseofulvin is an antibiotic fungistatic drug used in the treatment of dermatophyte and ringworm infections. About 50% of a dose of griseofulvin passes the gastro- intestinal tract unabsorbed and is excreted in faeces. Since griseofulvin is highly soluble in acidic pH, a gastro-retentive floating matrix system was developed to control dissolution rate and thereby enhance solubility in an effort to develop an improved and convenient dosage form. Preformulation studies included selection of excipients and evaluation of their co
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Wu, Hai-Yao, and 吳海瑤. "Preparation and sustained release property of gastro-floating tablets of roselle extract." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/7mkczx.

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碩士<br>國立中興大學<br>食品暨應用生物科技學系所<br>106<br>Rosell calyxes are bright red due to their rich anthocyanin. Many studies have confirmed that anthocyanins have good antioxidant activity. They have many physiological functions such as anti-inflammatory, anti-tumor, anti-cancer, and protection of eyesight. At present, people are eagerly pursuing health foods, and more and more raw materials with physiological effects are used to develop a lot of health foods. Tablet is one of the common types of health foods, with advantages of small size, convenient carrying, low cost, etc. This experiment aims to devel
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Choonara, Bibi Fatima. "A Tri-Functionalized Oral Core-Melt Tablet (OCMT) for enhanced delivery of gastro-sensitive proteins and synthetic peptides." Thesis, 2017. https://hdl.handle.net/10539/24911.

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A thesis submitted to the Faculty of Health Sciences, University of the Witwatersrand, in fulfillment of the requirements for the degree of Doctor of Philosophy. Department of Pharmacy and Pharmacology, University of the Witwatersrand, South Africa Johannesburg, 2017.<br>The global pharmaceutical biotechnology industry is continually growing and increased amounts of protein and peptide-based therapeutics are entering into the market. Conventionally, these therapeutic proteins and peptides are administered intravenously, subcutaneously or intramuscularly as oral routes of administration may r
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Book chapters on the topic "Floating Tablet A Gastro"

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Suvarna, Chittam, and Bhosale Ashok. "Design and Optimization of Novel Floating Agent Saccharomyces boulardii Probiotic Formulation Based Floating Tablet of Valsartan." In Techno-Societal 2022. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-34648-4_53.

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Ulmius, J., Z. G. Wagner, O. Borgå, and P. Wollmer. "Simultaneous Pharmacokinetic and in vivo Gamma Scintigraphic Monitoring in the Development of an Enprofylline-Sustained Release Tablet." In Drug Absorption at Different Regions of the Human Gastro-Intestinal Tract: Methods of Investigation and Results / Arzneimittelabsorption aus verschiedenen Bereichen des Gastrointestinaltraktes beim Menschen: Untersuchungsmethoden und Ergebnisse. Vieweg+Teubner Verlag, 1987. http://dx.doi.org/10.1007/978-3-322-91091-2_3.

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Latha, S. Madhavi, and P. Bharghava Bhushan. "Statistical Optimization and in Vitro Evaluation of Nizatidine Floating Tablets." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00586.

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Nizatidine is a histamine (H2) receptor antagonist that is indicated in the management of Gastric Esophageal Reflux Disorder, Peptic Ulcer Disease, gastric and duodenal ulcer. The bioavailabilty of Nizatidine is around 70% and the drug suffers from low permeability issues due to its hydrophilic nature. The aim of this work was to formulate and develop non effervescent floating matrix tablets of Nizatidine to increase the bioavailability of the drug by increasing gastric residence time. NEGFMT of Nizatidine were prepared using Glyceryl Laurate (GL), lactose, aerosol and magnesium stearate. 32 f
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Rajpoot, Kuldeep, Sunil K. Jain, and Saroj Dangi Rajpoot. "Gastro-retentive Nanocarriers in Drug Delivery." In Nanoparticles and Nanocarriers-Based Pharmaceutical Formulations. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815049787122010009.

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The oral route is an extremely accepted route for the administration of several drug delivery systems. This route exhibits several merits for the controlled and sustained release of different formulation types to attain enhanced therapeutic responses. Gastro-retentive nanocarriers (NCs) (GRNCs) have advantages due to their aptitude for extended retaining potential in the stomach environment and thereby elevate gastric retention and augmenting bioavailability of the drug molecules. This chapter covers various merits and demerits of gastro-retentive NCs. Further, it also discusses some gastro-re
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Pavan, A. Rajesh, Gorantla Naresh Babu, and Dr S. B. Thirumalesh Naik. "FLOATING MICROSPHERES A NEW TREND IN THE DELIVERY OF GASTRO RETENTIVE MEDICATIONS." In Futuristic Trends in Pharmacy & Nursing Volume 2 Book 25. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2023. http://dx.doi.org/10.58532/v2bs25p1ch5.

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There is no control over the delivery of conventional dose forms. Gastric resident time and gastric emptying are two crucial parameters that have a substantial impact on the drug's ability to treat certain conditions, and it produces differences in the drug's retention period. Drug levels in plasma change depending on the dosing type. As a result, among all gastro-retentive medication administration methods, the floating microsphere is one of the most dependable and creative methods to solve these issues. Due to their extreme appropriateness for targeting, floating microspheres are primarily g
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Singhal, Peeush, Rajneesh Dutt Kaushik, and Vijay Jyoti Kumar. "Preparation and in vitro Characterisation of Solid Dispersion Floating Tablet by Effervescent Control Release Technique with Improved Floating Capabilities." In Molecular Pharmacology. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.92187.

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In this research, an effort has been done for the development of effervescent controlled release floating tablet (ECRFT) from solid dispersions (SDs) of diclofenac sodium (DS) for upsurge the solubility and dissolution rate. ECRFT of DS was prepared by using SDs of DS and its SDs prepared with PEG as carrier using thermal method (simple fusion). SDs of DS was formulated in many ratios (1:1, 1:2, 1:3 and 1:4). Prepared SDs were optimised for its solubility, % drug content and % dissolution studies. Tablets were formulated by using optimised SDs products and all formulation was evaluated for var
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Firke, Sagar N., Ashish B. Roge, Pritam R. Siraskar, and Nitin B. Ghiware. "A Review on Floating Microspheres as Gastro-retentive Drug Delivery System." In Current Overview on Pharmaceutical Science Vol. 1. B P International (a part of SCIENCEDOMAIN International), 2022. http://dx.doi.org/10.9734/bpi/cops/v1/17077d.

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Srikar, Grandhi, and I. Nagamma. "Quality by Design Approach for Optimization and Development of Gastro-Retentive Hollow Microspheres for Prasugrel." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00414.

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Prasugrel (PSG) is used in minimizing the risk of atherothrombotic events in people with cardiovascular problems. Developing extended-release products for PSG is highly advantageous owing to its pharmacodynamic and pharmacokinetic properties. But, due to its insolubility in aqueous media with pH above 6.0, it becomes poorly bioavailable from the small intestine upon oral administration. Hence, an extended-release formulation which resides in gastric region until released completely is highly recommended. Polymeric hollow-microspheres with inherent floating property without lag time are highly
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Conference papers on the topic "Floating Tablet A Gastro"

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Krisanti, Elsa Anisa, Michael Gregory Budiatmadjaja, and Kamarza Mulia. "Formulation and characterization of gastro-retentive floating tablet contained curcuminoids from Curcuma Longa extracts for treatment of gastric ulcers." In THE 5TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, AND MEDICAL DEVICES: Proceedings of the 5th International Symposium of Biomedical Engineering (ISBE) 2020. AIP Publishing, 2021. http://dx.doi.org/10.1063/5.0047488.

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