Log in

Relevant bibliographies by topics / Fluoro / Journal articles

To see the other types of publications on this topic, follow the link: Fluoro.

Journal articles on the topic 'Fluoro'

Author: Grafiati

Published: 28 May 2022

Last updated: 30 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Fluoro.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Mieldažienė, Danguolė, and Ugnė Mažutytė. "SKIRTINGŲ KARTŲ TĖVŲ POŽIŪRIS Į VEIKSNIUS, LEMIANČIUS DANTŲ FLUOROZĖS ATSIRADIMĄ, JOS PROFILAKTIKĄ: KLAIPĖDOS APSKRITIES ATVEJIS." Health Sciences 33, no. 7 (2023): 83–87. http://dx.doi.org/10.35988/sm-hs.2023.280.

Full text

Abstract:

Dantų fluorozės paplitimo skirtumams įvairiose pasaulio valstybėse įtakos turi nevienodi rizikos veiksniai. Vienas iš jų − didelis fluoro junginių kiekis geriamojo vandens šaltiniuose [1]. Tėvų edukacija apie pasisavinamą fluoro kiekį, jo šaltinius bei neigiamą poveikį yra labai svarbi, siekiant išvengti nekariozinės kilmės dantų defekto − dantų fluorozės [2]. Tyrimo tikslas − atskleisti skirtingų kartų tėvų požiūrį į veiksnius, lemiančius dantų fluorozės atsiradimą ir jos profilaktiką Klaipėdos apskrityje. Taikyta kiekybinė tyrimo strategija. Tyrimui buvo pasirinkta netikimybinė proginė imti

APA, Harvard, Vancouver, ISO, and other styles

2

Umemoto, Teruo, Yuhao Yang, and Gerald B. Hammond. "Development of N-F fluorinating agents and their fluorinations: Historical perspective." Beilstein Journal of Organic Chemistry 17 (July 27, 2021): 1752–813. http://dx.doi.org/10.3762/bjoc.17.123.

Full text

Abstract:

This review deals with the historical development of all N-F fluorinating agents developed so far. The unique properties of fluorine make fluorinated organic compounds attractive in many research areas and therefore fluorinating agents are important. N-F agents have proven useful by virtue of their easy handling. This reagent class includes many types of N-F compounds: perfluoro-N-fluoropiperidine, N-fluoro-2-pyridone, N-fluoro-N-alkylarenesulfonamides, N-fluoropyridinium salts and derivatives, N-fluoroquinuclidium salts, N-fluoro-trifluoromethanesulfonimide, N-fluoro-sultams, N-fluoro-benzoth

APA, Harvard, Vancouver, ISO, and other styles

3

Fedko, Nadiia F., Valeriy F. Anikin, and Vira V. Veduta. "The synthesis of N-substituted 4-fluoro-1,8-naphthalimides." Journal of Organic and Pharmaceutical Chemistry 20, no. 3 (2022): 25–30. http://dx.doi.org/10.24959/ophcj.22.263203.

Full text

Abstract:

Aim. To synthesize 4-fluoro-1,8-naphthalic acid imide and its derivatives substituted in the imide ring.Results and discussion. 4-Fluoro-1,8-naphthalimide was obtained using acenaphthene as the starting material. N-alkyl-4-fluoro-1,8-naphthalimides were synthesized via the phase transfer catalytic alkylation of 4-fluoro-1,8-naphthalimide with haloalkanes. Imidation of 4-fluoro-1,8-naphthalic anhydride with aminoacids resulted in the formation of N-carboxyalkyl-1,8-naphthalimides. These substances can be considered as potential fluorescent labels capable of binding to amino groups of various bi

APA, Harvard, Vancouver, ISO, and other styles

4

Seither, Joshua Z., Lisa J. Reidy, and Diane M. Boland. "Identification and Quantification of 5-Fluoro ADB and the 5-Fluoro ADB Ester Hydrolysis Metabolite in Postmortem Blood Samples by LC–MS/MS." Journal of Analytical Toxicology 44, no. 2 (2019): 133–39. http://dx.doi.org/10.1093/jat/bkz043.

Full text

Abstract:

Abstract 5-Fluoro ADB, also known as 5-fluoro MDMB-PINACA, is a potent synthetic cannabinoid that is an agonist to the human cannabinoid CB1 and CB2 receptors. Adverse physiological and psychological effects that have resulted in hospitalization and/or death have been associated with 5-Fluoro ADB use. In addition, analytical confirmation of 5-Fluoro ADB use has been reported in both forensic human performance toxicology and postmortem cases. An analytical method for the identification and quantification of 5-fluoro ADB and the 5-fluoro ADB ester hydrolysis metabolite in human blood samples by

APA, Harvard, Vancouver, ISO, and other styles

5

Dubuffet, Thierry, Raymond Sauvêtre, and Jean-F. Normant. "Préparation de fluoro-oxirannes et fluoro-silyloxirannes." Journal of Organometallic Chemistry 354, no. 1 (1988): 1–6. http://dx.doi.org/10.1016/0022-328x(88)80632-6.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Jindřich, Jindřich, Hana Dvořáková, and Antonín Holý. "Synthesis of Isomeric N-(3-Fluoro-2-hydroxypropyl) and N-(2-Fluoro-3-hydroxypropyl) Derivatives of Purine and Pyrimidine Bases." Collection of Czechoslovak Chemical Communications 57, no. 7 (1992): 1466–82. http://dx.doi.org/10.1135/cccc19921466.

Full text

Abstract:

Reaction of fluoromethyloxirane (III) with heterocyclic bases in the presence of potassium carbonate afforded N-(3-fluoro-2-hydroxypropyl) derivatives of adenine (VI), 3-deazaadenine (VII), 2-amino-6-chloropurine (XII), 6-nitro-1-deazapurine (IX), 4-methoxy-2-pyrimidone (XVIII) and its 5-methyl derivative (XIX). Acid hydrolysis of compounds XII, XVIII, and XIX gave 9-(3-fluoro-2-hydroxypropyl)guanine (XIII), 1-(3-fluoro-2-hydroxypropyl)uracil (XX) and -thymine (XXI). The intermediates XVIII and XIX were ammonolyzed to give 1-(3-fluoro-2-hydroxypropyl)cytosine (XXII) and -5-methylcytosine (XXII

APA, Harvard, Vancouver, ISO, and other styles

7

Ikeda, I., M. Tsuji, and M. Okahara. "Fluoro Surfactants." Tenside Surfactants Detergents 24, no. 5 (1987): 272–75. http://dx.doi.org/10.1515/tsd-1987-240512.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Sudlow, Kevin, and Alfred A. Woolf. "Destabilization of fluoro imino and fluoro oxy compounds." Journal of Fluorine Chemistry 73, no. 1 (1995): 47–50. http://dx.doi.org/10.1016/0022-1139(94)03196-7.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Rao, R. Kanna, and N. Syam Sundar. "Vibrational spectra of 2-fluoro-5-nitro-, 2-fluoro-4-nitro-, 4-fluoro-2-nitro- and 5-fluoro-2-nitrotoluene." Spectrochimica Acta Part A: Molecular Spectroscopy 49, no. 12 (1993): 1691–93. http://dx.doi.org/10.1016/0584-8539(93)80235-3.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Zhang, E., Heng Guo, Dandan Chen, et al. "Mutational biosynthesis to generate novel analogs of nosiheptide featuring a fluorinated indolic acid moiety." Organic & Biomolecular Chemistry 18, no. 21 (2020): 4051–55. http://dx.doi.org/10.1039/d0ob00084a.

Full text

Abstract:

The target product 6′-fluoro-nosiheptide (6′-F-NOS), along with 6′-fluoro-nosiheptide intermediate (NOS 6′-F-NOSint), was obtained by mutational biosynthesis via 6′-fluoro-MIA feeding into mutant NosL.

APA, Harvard, Vancouver, ISO, and other styles

11

Wang, Xin, Jia Lei, Guofeng Li, et al. "Synthetic methods for compounds containing fluoro-lactam units." Organic & Biomolecular Chemistry 18, no. 48 (2020): 9762–74. http://dx.doi.org/10.1039/d0ob02168g.

Full text

Abstract:

This review highlights recent progress in the construction of fluorinated lactams, including fluoro-β-lactams, fluoro-γ-lactams, and fluoro-δ-lactams, with an emphasis on the scopes, limitations and mechanisms of these different reactions.

APA, Harvard, Vancouver, ISO, and other styles

12

Block, Eric, Benjamin Bechand, Sivaji Gundala, Abith Vattekkatte, and Kai Wang. "Fluorinated Analogs of Organosulfur Compounds from Garlic (Allium sativum): Synthesis and Chemistry." Molecules 30, no. 13 (2025): 2841. https://doi.org/10.3390/molecules30132841.

Full text

Abstract:

We report the first syntheses—from commercially available 3-chloro-2-fluoroprop-1-ene (9)—of key garlic-derived compounds containing sp2-fluorine. We also report synthesis of fluoro-5,6-dihydrothiopyrans by trapping 2-fluorothioacrolein (15). Thus, difluoroallicin (12, S-(2-fluoro-2-propenyl) 2-fluoroprop-2-ene-1-sulfinothioate) is prepared by peracid oxidation of 1,2-bis(2-fluoro-2-propenyl)disulfane (11). S-2-Fluoro-2-propenyl-l-cysteine (2-fluorodeoxyalliin, 13), synthesized from cysteine and characterized by X-ray crystallography, is oxidized to its S-oxide, 2-fluoroalliin (22). The latter

APA, Harvard, Vancouver, ISO, and other styles

13

Offer, J., J. C. Metcalfe, and G. A. Smith. "The uptake of 3H-labelled monodeoxyfluoro-myo-inositols into thymocytes and their incorporation into phospholipid in permeabilized cells." Biochemical Journal 291, no. 2 (1993): 553–60. http://dx.doi.org/10.1042/bj2910553.

Full text

Abstract:

Monodeoxyfluoro-myo-inositols were applied to electropermeabilized and intact thymocyte preparations to study their metabolism and uptake in order to investigate their suitability as potential inhibitors of phosphoinositide-mediated cellular responses. Only three of the monodeoxyfluoro-myo-inositols were incorporated into the phospholipids of thymocytes: 1D-3-deoxy-3-fluoro-myo-inositol, 5-deoxy-5-fluoro-myo-inositol and 1D-6-deoxy-6-fluoro-myo-inositol, all of which were weaker substrates for phosphatidylinositol synthase than was myo-inositol. The 3-, 5- and 6-fluoro analogues also behaved a

APA, Harvard, Vancouver, ISO, and other styles

14

Tišlerová, Iva, Václav Richtr та Jiří Klinot. "Conformation Study of A-Ring in 19β,28-Epoxy-2-fluoro-18α-oleananes". Collection of Czechoslovak Chemical Communications 71, № 3 (2006): 368–86. http://dx.doi.org/10.1135/cccc20060368.

Full text

Abstract:

A series of 2-fluoro-substituted 19β,28-epoxy-18α-oleanane triterpenoids was prepared. Detailed NMR analysis (1H, 13C, 19F) was used for independent determination of the configuration of substituents. Conformation of the A-ring was derived from coupling constants J(H,H), J(F,H), J(F,C) and NOE-contacts observed in 2D-H,H-NOESY spectra. It was found that A-ring in all 2α-fluoro derivatives 2-5 and 2β-fluoro-3β-OR derivatives 10 and 11 adopts chair-form, while in 2β-fluoro ketone 9 a boat-form is preferred. The chair-boat equilibrium of A-ring was found in 2β-fluoro-3α-OR derivatives 7 and 8.

APA, Harvard, Vancouver, ISO, and other styles

15

Slavíková, Barbora, Alexander Kasal, Hana Chodounská та Zdena Krištofíková. "3α-Fluoro Analogues of "Allopregnanolone" and Their Binding to GABAA Receptors". Collection of Czechoslovak Chemical Communications 67, № 1 (2002): 30–46. http://dx.doi.org/10.1135/cccc20020030.

Full text

Abstract:

(Diethylamino)sulfur trifluoride (DAST) was used for the preparation of 3α-fluorides (e.g., 3α-fluoro-5α-pregnane-12,20-dione, 3α-fluoro-16α-[(methoxycarbonyl)methyl]-5α-pregnan-20-one, methyl 3α-fluoro-5α-androstane-17β-carboxylate, 3α-fluoro-5β-pregnan-20-one) from the corresponding 3β-alcohols and for the preparation of 3,3-difluorides from 3-ketones (e.g., 3,3-difluoro-5α-pregnan-20-one). Boron trifluoride etherate was used for the conversion of an epoxide into 3α-fluoro-2β-hydroxy-5α-pregnan-20-one. The in vitro binding of the 3α-fluorides and the corresponding 3α-alcohols to the GABAA re

APA, Harvard, Vancouver, ISO, and other styles

16

Chirakal, Raman, Gary J. Schrobilgen, Gunter Firnau, and Stephen Garnett. "Synthesis of 18F labelled fluoro-m-tyrosine, fluoro-m-tyramine and fluoro-3-hydroxyphenylacetic acid." International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes 42, no. 2 (1991): 113–19. http://dx.doi.org/10.1016/0883-2889(91)90059-a.

Full text

APA, Harvard, Vancouver, ISO, and other styles

17

Klösener, J., D. C. Swenson, L. W. Robertson, and G. Luthe. "Effects of fluoro substitution on 4-bromodiphenyl ether (PBDE 3)." Acta Crystallographica Section B Structural Science 64, no. 1 (2008): 108–19. http://dx.doi.org/10.1107/s0108768107067079.

Full text

Abstract:

It is our hypothesis that fluoro substitution provides a powerful tool to modulate the desired characteristics and to increase the specificity of studies of structure–activity relationships. 4-Bromodiphenyl ether (PBDE 3) and its five corresponding monofluorinated analogues (F-PBDEs 3) have been synthesized and fully characterized (using 1H, 13C and 19F NMR spectroscopy, and mass spectrometry). The accurate structure from X-ray crystal analysis was compared with iterative calculations using semi-empirical self-consistent field molecular-orbital (SCF-MO) models. The compounds studied were 4-bro

APA, Harvard, Vancouver, ISO, and other styles

18

Heeran, Darren, Ben J. Murray, Sili Qiu, et al. "Synthesis of polyfunctional fluoro-quinoline and fluoro-pyridopyrimidinone derivatives." Journal of Fluorine Chemistry 249 (September 2021): 109830. http://dx.doi.org/10.1016/j.jfluchem.2021.109830.

Full text

APA, Harvard, Vancouver, ISO, and other styles

19

Chopra, Deepak, T. P. Mohan, and B. Vishalakshi. "4-Fluoro-N′-(4-fluoro-3-phenoxybenzoyl)-3-phenoxybenzohydrazide." Acta Crystallographica Section E Structure Reports Online 62, no. 7 (2006): o3085—o3086. http://dx.doi.org/10.1107/s1600536806024342.

Full text

APA, Harvard, Vancouver, ISO, and other styles

20

Riesel, L., D. Sturm, A. Zschunke та B. Thomas. "Fluoro-λ-Monophosphazenes and Fluoro-1.3-Diaza-2δ5,4δ5-Diphosphetidines". Phosphorus and Sulfur and the Related Elements 30, № 3-4 (1987): 801. http://dx.doi.org/10.1080/03086648708079293.

Full text

APA, Harvard, Vancouver, ISO, and other styles

21

Mistry, Bhavnaben D., Kishor R. Desai, and Nigam J. Desai. "SYNTHESIS, IN VITRO ANTIMICROBIAL ACTIVITY OF SCHIFF’S BASE, AZETIDINONES AND THIAZOLIDINONES." International Journal of Current Pharmaceutical Research 9, no. 1 (2016): 126. http://dx.doi.org/10.22159/ijcpr.2017v9i1.16634.

Full text

Abstract:

Objective: The objective of the present study is to synthesize 3-Chloro-4-[3-(2,4-dichloro-5-fluoro phenyl)-1H-pyrazol-4-yl]-1-(substituted) azetidin-2-one [4a-n] and 2-[3-(2,4-Dichloro-5-fluoro phenyl)-1H-pyraol-4-yl]-3-(substituted phenyl)-1,3-thiazolidin-4-one [5a-n]. The structure of all synthesized compounds were characterized by IR, 1H NMR, 13C NMR and mass spectral studies. Methods: The titled compounds 3-Chloro-4-[3-(2,4-dichloro-5-fluoro phenyl)-1H-pyrazol-4-yl]-1-(substituted) azetidin-2-one [4a-n] and 2-[3-(2,4-Dichloro-5-fluoro phenyl)-1H-pyraol-4-yl]-3-(substituted phenyl)-1,3-thi

APA, Harvard, Vancouver, ISO, and other styles

22

Redondo, Alejandro, Gabriela Riego, and Olga Pol. "The Antinociceptive, Antioxidant and Anti-Inflammatory Effects of 5-Fluoro-2-Oxindole during Inflammatory Pain." Antioxidants 9, no. 12 (2020): 1249. http://dx.doi.org/10.3390/antiox9121249.

Full text

Abstract:

Recent studies demonstrate that 5-fluoro-2-oxindole inhibits neuropathic pain but the antinociceptive actions of this drug and its effects on the plasticity, oxidative and inflammatory changes induced by peripheral inflammation as well as on the effects and expression of µ-opioid receptors (MOR) have not been evaluated. In C57BL/6 male mice with inflammatory pain provoked by the subplantar administration of complete Freund’s adjuvant (CFA), we evaluated: (1) the antinociceptive actions of 5-fluoro-2-oxindole and its reversion with the HO-1 inhibitor, tin protoporphyrin IX (SnPP); (2) the effec

APA, Harvard, Vancouver, ISO, and other styles

23

Hanafy, Nemany A., Marzia Maria Ferraro, Antonio Gaballo та ін. "Fabrication and characterization of ALK1fc-loaded fluoro-magnetic nanoparticles for inhibiting TGF β1 in hepatocellular carcinoma". RSC Advances 6, № 54 (2016): 48834–42. http://dx.doi.org/10.1039/c6ra06345d.

Full text

APA, Harvard, Vancouver, ISO, and other styles

24

Ocampo, Rogelio, William R. Dolbier та Fabio Zuluaga. "Synthesis of α-Fluoro-β-lactones and Their Thermal Conversion to 1-Fluoroalkenes". Collection of Czechoslovak Chemical Communications 67, № 9 (2002): 1325–34. http://dx.doi.org/10.1135/cccc20021325.

Full text

Abstract:

α-Fluoro-β-lactones have been synthesized and isolated for the first time from α-fluoro-β-hydroxy acids by using the couple TsCl/DMAP as lactonization agent. A detailed description of the synthesis and spectroscopic properties of α-fluoro-β-lactones is presented. Preliminary results indicate that thermolysis of these new β-lactones produces 1-fluoroalkenes.

APA, Harvard, Vancouver, ISO, and other styles

25

Best, Wayne M., Robert V. Stick та D. Matthew G. Tilbrook. "The Synthesis of Some Epoxyalkyl Deoxyhalo-β-cellobiosides". Australian Journal of Chemistry 50, № 1 (1997): 13. http://dx.doi.org/10.1071/c96078.

Full text

Abstract:

2,3-Epoxypropyl and 3,4-epoxybutyl 6′-deoxy-6′-iodo-β-cellobioside, together with 3,4-epoxybutyl 6′- deoxy-6′-fluoro-β-cellobioside, were prepared as putative inhibitors and reporter groups for events occurring at the active site of some β-glucan hydrolases. As well, related syntheses gave the previously unknown 6-deoxy-6-fluoro- and 6′-deoxy-6′-fluoro-cellobioses.

APA, Harvard, Vancouver, ISO, and other styles

26

Tarui, Atsushi, Yukiko Karuo, Kazuyuki Sato, Kentaro Kawai та Masaaki Omote. "Stereoselective Synthesis of Multisubstituted α-fluoro-β-lactams". Current Organic Chemistry 24, № 18 (2020): 2169–80. http://dx.doi.org/10.2174/1385272824666200221114707.

Full text

Abstract:

β-Lactams, found in β -lactam antibiotics, are the structurally distorted cyclic compounds being subjected to nucleophilic acyl substitution reaction. α-Fluorination of β -lactams is a simple and expedient approach to control the reactivity of β-lactam ring toward nucleophilic attack, which would hopefully lead to the new design of future antibiotics. From the viewpoint of obtaining multisubstituted α -fluoro-β-lactams, α -bromo-α- fluoro-β-lactams are considered as key compounds for structure functionalization, including nucleophilic substitution reaction, aldol-type reaction and metal-cataly

APA, Harvard, Vancouver, ISO, and other styles

27

Böttcher, Olaf, and Dieter H. Sutter. "Nitrogen Quadrupole Hyperfine Structure in the Rotational Spectrum of 2-,3-,and 4-Fluoro-Benzonitrile.A Comparative High Resolution Microwave Fourier Transform Study." Zeitschrift für Naturforschung A 43, no. 1 (1988): 47–58. http://dx.doi.org/10.1515/zna-1988-0107.

Full text

Abstract:

Abstract A microwave Fourier transform study of the rotational spectrum of 3-fluoro-benzonitrile was carried out to study the 14N quadrupole coupling and to give improved rotational constants and centrifugal distortion parameters. In order to fully exploit the high resolution inherent to the experimental technique, frequencies, linewidths, intensities and phases were directly fitted to the observed transient emission signals. The quadrupole coupling constants are discussed in comparison to those of the related molecules 2-fluoro-benzonitrile, 4-fluoro-benzonitrile, and benzonitrile itself. For

APA, Harvard, Vancouver, ISO, and other styles

28

Haase, Linn, and Klaus Weisz. "Switching the type of V-loop in sugar-modified G-quadruplexes through altered fluorine interactions." Chemical Communications 56, no. 33 (2020): 4539–42. http://dx.doi.org/10.1039/d0cc01285h.

Full text

APA, Harvard, Vancouver, ISO, and other styles

29

Solodinin, Andrei, James Helmkay, Samuel Ollivier, and Hongbin Yan. "8-Fluoro-N-2-isobutyryl-2′-deoxyguanosine: Synthesis and Reactivity." Molbank 2020, no. 1 (2020): M1119. http://dx.doi.org/10.3390/m1119.

Full text

Abstract:

3′,5′-O-Bis(tert-butyldimethylsilyl)-8-fluoro-N-2-isobutyryl-2′-deoxyguanosine was synthesized from 3′,5′-O-bis(tert-butyldimethylsilyl)-N-2-isobutyryl-2′-deoxyguanosine by the treatment with N-fluorobenzenesulfonimide. A similar fluorination reaction with 3′,5′-O-bis(tert-butyldimethylsilyl)-N-2-(N,N-dimethylformamidine)-2′-deoxyguanosine, however, failed to give the corresponding fluorinated product. It was found that 8-fluoro-N-2-isobutyryl-2′-deoxyguanosine is labile under acidic conditions, but sufficiently stable in dichloroacetic acid used in solid phase synthesis. Incorporation of 8-fl

APA, Harvard, Vancouver, ISO, and other styles

30

KRISHNA, C. JOSHI, N. PATHAK VIJAI, and CHAND POORAN. "Mass Spectral Studies on Heterocyclic Compounds. Part -I. Fragmentation of some Fluorine containing Indole Derivatives under Electron Impact." Journal of Indian Chemical Society Vol. 64, Feb 1987 (1987): 111–13. https://doi.org/10.5281/zenodo.6217752.

Full text

Abstract:

Department of Chemistry, University of Rajasthan, Jaipur-302 004 <em>Manuscript received 21 August 1980, accepted 22 January 1987</em> The fragmentation pathways of 5-)6-fluoro-2-(4'-fluorophenyl)indoles, 5-fluoro-2- (4' -fluorophenyI)-3- <em>(N,N-</em>dimethy Iglyoxy lamido)indol e, 5-fluoro -2- (4'-fluorophenyl)-3-(β- morpholinoethyl) indole and 5-fluoro-3-(4'-fluorophenylimino)-1-piperidino-methylindo1-2- one have been studied. Structural assignments have been made for the major fragments, and the pathways leading to their formation have been postulated by the recogniti

APA, Harvard, Vancouver, ISO, and other styles

31

McConkey, Glenn A. "Targeting the Shikimate Pathway in the Malaria Parasite Plasmodium falciparum." Antimicrobial Agents and Chemotherapy 43, no. 1 (1999): 175–77. http://dx.doi.org/10.1128/aac.43.1.175.

Full text

Abstract:

ABSTRACT The shikimate pathway presents an attractive target for malaria chemotherapy. Three shikimic acid analogs exhibited different effects on Plasmodium falciparum growth. (6R)-6-Fluoro-shikimate and (6S)-6-fluoro-shikimate inhibited growth (50% inhibitory concentrations, 1.5 × 10−5 and 2.7 × 10−4 M, respectively), whereas 2-fluoro-shikimate had no effect. para-Aminobenzoic acid abrogated the inhibition, demonstrating that the shikimate pathway was specifically targeted.

APA, Harvard, Vancouver, ISO, and other styles

32

Luthe, G., D. C. Swenson, and L. W. Robertson. "Influence of fluoro-substitution on the planarity of 4-chlorobiphenyl (PCB 3)." Acta Crystallographica Section B Structural Science 63, no. 2 (2007): 319–27. http://dx.doi.org/10.1107/s0108768106054255.

Full text

Abstract:

Accurate structure determinations by X-ray crystal analysis and computation using semi-empirical self-consistent field molecular orbital calculations are described and compared for five monofluorinated analogues of 4-chlorobiphenyl, i.e. 2-fluoro-4-chlorobiphenyl, 2′-fluoro-4-chlorobiphenyl, 3-fluoro-4-chlorobiphenyl, 3′-fluoro-4-chlorobiphenyl and 4′-fluoro-4-chlorobiphenyl. Intermolecular interactions for all monofluorinated isomers are dominated by phenyl–phenyl stacking and C—H–phenyl interactions. C—F bond lengths varied between 1.341 and 1.374 Å, C—Cl between 1.733 and 1.765 Å, and both

APA, Harvard, Vancouver, ISO, and other styles

33

Basenko, S. V., M. G. Voronkov, E. V. Boyarkina, S. I. Lopatin, I. A. Gebel’, and L. E. Zelenkov. "Oligophenyl(fluoro)siloxanes." Russian Journal of General Chemistry 78, no. 8 (2008): 1635–37. http://dx.doi.org/10.1134/s1070363208080318.

Full text

APA, Harvard, Vancouver, ISO, and other styles

34

Basenko, S. V., L. E. Zelenkov, M. G. Voronkov, and A. I. Albanov. "Phenyl(fluoro)chlorodisiloxanes." Russian Journal of General Chemistry 80, no. 2 (2010): 242–44. http://dx.doi.org/10.1134/s107036321002009x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

35

Uneyama, Kenji, Hidekl Asai, Yasufumi Dan-oh, and Hiroshi Funatsuki. "Electrochemical Fluoro-Chalcogenation." Phosphorus, Sulfur, and Silicon and the Related Elements 120, no. 1 (1997): 395–96. http://dx.doi.org/10.1080/10426509708043997.

Full text

APA, Harvard, Vancouver, ISO, and other styles

36

Ama, Kenji Uney, Hideki Asai, Yasufumi Dan-Oh, and Hiroshi Funatsuki. "Electrochemical Fluoro-Chalcogenation." Phosphorus, Sulfur, and Silicon and the Related Elements 120, no. 1 (1997): 395–96. http://dx.doi.org/10.1080/10426509708545565.

Full text

APA, Harvard, Vancouver, ISO, and other styles

37

Megges, R., W. Rollka, J. Weiland, P. Franke, H. J. Portius, and W. Schönfeld. "21-Fluoro-cardenolides." Journal of Fluorine Chemistry 29, no. 1-2 (1985): 181. http://dx.doi.org/10.1016/s0022-1139(00)83417-x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

Gilsing, H. D., D. Prescher, and R. Wagner. "Novel fluoro surfactants." Tenside Surfactants Detergents 35, no. 4 (1998): 240–47. http://dx.doi.org/10.1515/tsd-1998-350403.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

Hanessian, Stephen, Oscar M. Saavedra, Miguel A. Vilchis-Reyes, and Ana M. Llaguno-Rueda. "Synthesis of 4′-deoxy-4′-fluoro neamine and 4′-deoxy-4′-fluoro 4′-epi neamine." MedChemComm 5, no. 8 (2014): 1166–71. http://dx.doi.org/10.1039/c4md00072b.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Kas, Aurélie, Michel Bottlaender, Jean Dominique Gallezot, et al. "Decrease of Nicotinic Receptors in the Nigrostriatal System in Parkinson's Disease." Journal of Cerebral Blood Flow & Metabolism 29, no. 9 (2009): 1601–8. http://dx.doi.org/10.1038/jcbfm.2009.74.

Full text

Abstract:

Smoking is associated with a lower incidence of Parkinson's disease (PD), which might be related to a neuroprotective action of nicotine. Postmortem studies have shown a decrease of cerebral nicotinic acetylcholine receptors (nAChRs) in PD. In this study, we evaluated the decrease of nAChRs in PD in vivo using positron emission tomography (PET), and we explored the relationship between nAChRs density and PD severity using both clinical scores and the measurement of striatal dopaminergic function. Thirteen nondemented patients with PD underwent two PET scans, one with 6-[18F]fluoro-3,4-dihydrox

APA, Harvard, Vancouver, ISO, and other styles

41

Horník, Štěpán, Lucie Červenková Šťastná, Petra Cuřínová, et al. "Synthesis and in vitro cytotoxicity of acetylated 3-fluoro, 4-fluoro and 3,4-difluoro analogs of D-glucosamine and D-galactosamine." Beilstein Journal of Organic Chemistry 12 (April 20, 2016): 750–59. http://dx.doi.org/10.3762/bjoc.12.75.

Full text

Abstract:

Background: Derivatives of D-glucosamine and D-galactosamine represent an important family of the cell surface glycan components and their fluorinated analogs found use as metabolic inhibitors of complex glycan biosynthesis, or as probes for the study of protein–carbohydrate interactions. This work is focused on the synthesis of acetylated 3-deoxy-3-fluoro, 4-deoxy-4-fluoro and 3,4-dideoxy-3,4-difluoro analogs of D-glucosamine and D-galactosamine via 1,6-anhydrohexopyranose chemistry. Moreover, the cytotoxicity of the target compounds towards selected cancer cells is determined. Results: Intro

APA, Harvard, Vancouver, ISO, and other styles

42

Zhou, Jiadi, Ye Fang, Fang Wang та Jianjun Li. "Catalyst-free regioselective hydroxyfluorination and aminofluorination of α,β-unsaturated ketones". Organic & Biomolecular Chemistry 17, № 18 (2019): 4470–74. http://dx.doi.org/10.1039/c9ob00467j.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

Xie, Guang Yong, Xiang Zhang, Xiao Hang Xu, Ting Cheng Li та Ai Qing Zhang. "Electronic Effect of Fluoro Substituents on Chromium(III) Complexes bearing β-Diketiminate Ligands for Ethylene Polymerization". Advanced Materials Research 476-478 (лютий 2012): 2201–4. http://dx.doi.org/10.4028/www.scientific.net/amr.476-478.2201.

Full text

Abstract:

A series of new chromium(III) complexes bearing fluoro-substituted β-diketiminate ligands have been synthesized and characterized by IR and elemental analyses. When activated by modified methylaluminoxane (MMAO), these Cr complexes exhibited moderate or high activities for ethylene polymerization (up to 370 g.mmol-1.h-1). Various reaction parameters such as reaction temperature and Al/Cr ratio were investigated in detail. Further more, it was found for the first time that the catalytic behaviors of Cr complexes can be greatly influenced by the electronic effect of fluoro substituents. The intr

APA, Harvard, Vancouver, ISO, and other styles

44

Hiebl, J., E. Zbiral, M. von Janta-Lipinski, J. Balzarini, and E. De Clercq. "Side-Chain Derivatives of Biologically Active Nucleosides. Part 2: Synthesis and anti-HIV Activity of 5′-C-Methyl Derivatives of 3′-Fluoro-3′-Deoxythymidine." Antiviral Chemistry and Chemotherapy 7, no. 3 (1996): 173–77. http://dx.doi.org/10.1177/095632029600700308.

Full text

Abstract:

1-(3′-Fluoro-2′,3′,6′-trideoxy-β-D-allofuranosyl)thymine [7] and 1-(3′-fluoro-2′,3′,6′-trideoxy-α-L-talofuranosyl) thymine [8] were synthesized starting from the corresponding 2,3′-anhydro nucleoside derivatives. The fluorine was introduced stereoselectively by opening of the anhydro bridge in the presence of HF/AIF3. The 5′-C-methyl derivatives, [7] and [8], of 3′-fluoro-3′-deoxythymidine (FLT) were evaluated for their inhibitory effect against human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2). The compounds [7] and [8] had antiviral activity which was three orders of magnitude l

APA, Harvard, Vancouver, ISO, and other styles

45

Bae, Jun-Young, Hwea-Yoon Kim, Young-Woo Lim, Yoon-Hyeok Kim, and Byeong-Soo Bae. "Optically recoverable, deep ultraviolet (UV) stable and transparent sol–gel fluoro siloxane hybrid material for a UV LED encapsulant." RSC Advances 6, no. 32 (2016): 26826–34. http://dx.doi.org/10.1039/c6ra01346e.

Full text

APA, Harvard, Vancouver, ISO, and other styles

46

Cambie, RC, KC Higgs, JJ Rustenhoven, and PS Rutledge. "Experiments Directed Towards the Synthesis of Anthracyclinones. XXIX. Fluoro-Substituted Tetracycles." Australian Journal of Chemistry 49, no. 7 (1996): 751. http://dx.doi.org/10.1071/ch9960751.

Full text

Abstract:

Diastereoselective formation of 9-fluoro-9-methylanthracyclinones has been achieved by treating ortho-methallyl-substituted anthraquinonyl homochiral dioxans with boron trifluoride etherate . The demethoxy anthraquinonyl dioxan (16) underwent slow reaction to give exclusively the (7S,9R) fluoro tetracycle (21) in 58% yield. The dimethoxy anthraquinonyl dioxan (15) was less reactive, allowing other reactions to compete, but boron trifluoride -acetic acid complex effected rapid cyclization of (15) with high diastereoselectivity. Short reaction times with this reagent circumvented the formation o

APA, Harvard, Vancouver, ISO, and other styles

47

Jiang, Min, Yong-Jun Liu, Guo-Song Liu, et al. "Sequential resolution of (S) and (R)-6-fluoro-chroman-2-carboxylic acid by two esterases in turn." Green Chemistry 24, no. 8 (2022): 3235–42. http://dx.doi.org/10.1039/d1gc04512a.

Full text

APA, Harvard, Vancouver, ISO, and other styles

48

Tian, Wei, Spiros Grivas, and Kjell Olsson. "Nitration of 5-fluoro-2,1,3-benzoselenadiazoles, and the synthesis of 4-fluoro3-nitro-, 4-fluoro-6-nitro-, 5-fluoro-3-nitro-o-phenylenediamines and 3,4-diamino-2-nitrophenols by subsequent deselenation." Journal of the Chemical Society, Perkin Transactions 1, no. 2 (1993): 257. http://dx.doi.org/10.1039/p19930000257.

Full text

APA, Harvard, Vancouver, ISO, and other styles

49

Wong, Alexander W., Shouming He та Stephen G. Withers. "Synthesis of 5-fluoro-β-D-glucopyranosyluronic acid fluoride and its evaluation as a mechanistic probe of Escherichia coli β-glucuronidase". Canadian Journal of Chemistry 79, № 5-6 (2001): 510–18. http://dx.doi.org/10.1139/v00-155.

Full text

Abstract:

Synthesis of the potential mechanism-based inactivator of β-D-glucuronidases (5-fluoro-β-D-glucopyranosyluronic acid fluoride) was accomplished via a six-step process from D-glucuronic acid that involved radical bromination at C-5 and displacement of the bromide by fluoride. A key step in this process was the masking of the carboxylic acid as a phenacyl ester. This group is uniquely stable to conditions of photobromination and fluoride displacement, yet removable under very mild conditions. Incubation of the Escherichia coli β-glucuronidase with 5-fluoro-β-D-glucopyranosyluronic acid fluoride

APA, Harvard, Vancouver, ISO, and other styles

50

Protiva, Miroslav, Jiří Jílek, Miroslav Rajšner, et al. "Fluorinated tricyclic neuroleptics with prolonged action: 7-Fluoro-11-[4-(2-hydroxyethyl)piperazino]-2-isopropyl-10,11-dihydrodibenzo[b,f]thiepin." Collection of Czechoslovak Chemical Communications 51, no. 3 (1986): 698–722. http://dx.doi.org/10.1135/cccc19860698.

Full text

Abstract:

Substitution reaction of 11-chloro-7-fluoro-2-isopropyl-10,11-dihydrodibenzo[b,f,]thiepin with 1-(2-hydroxyethyl)piperazine gave the title compound I which proved a very potent and longacting oral neuroleptic agent (isofloxythepin). Its resolution by means of dibenzoyl-(+)- and -(-)-tartaric acid led to (-)- and (+)-enantiomer out of which the former represents the neuroleptically active component. In the synthetic sequence leading to I, preparation of two key intermediates was re-elaborated using new partial sequences: 4-fluoro-2-iodobenzoic acid (XIII) from 4-fluoro-2-nitroaniline (V) via th

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!