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Relevant bibliographies by topics / Focal Osteoarthritic Cartilage Lesions

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Academic literature on the topic 'Focal Osteoarthritic Cartilage Lesions'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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Journal articles on the topic "Focal Osteoarthritic Cartilage Lesions"

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Pattappa, Girish, Jonas Krueckel, Ruth Schewior, et al. "Physioxia Expanded Bone Marrow Derived Mesenchymal Stem Cells Have Improved Cartilage Repair in an Early Osteoarthritic Focal Defect Model." Biology 9, no. 8 (2020): 230. http://dx.doi.org/10.3390/biology9080230.

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Focal early osteoarthritis (OA) or degenerative lesions account for 60% of treated cartilage defects each year. The current cell-based regenerative treatments have an increased failure rate for treating degenerative lesions compared to traumatic defects. Mesenchymal stem cells (MSCs) are an alternative cell source for treating early OA defects, due to their greater chondrogenic potential, compared to early OA chondrocytes. Low oxygen tension or physioxia has been shown to enhance MSC chondrogenic matrix content and could improve functional outcomes of regenerative therapies. The present invest

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David-Vaudey, E., A. Burghardt, K. Keshari, A. Brouchet, M. Ries, and S. Majumdar. "Fourier transform infrared imaging of focal lesions in Human osteoarthritic cartilage." European Cells and Materials 10 (November 22, 2005): 51–60. http://dx.doi.org/10.22203/ecm.v010a06.

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Lee, Keh-Yang, Timothy C. Dunn, Lynne S. Steinbach, Eugene Ozhinsky, Michael D. Ries, and Sharmila Majumdar. "Computer-aided quantification of focal cartilage lesions of osteoarthritic knee using MRI." Magnetic Resonance Imaging 22, no. 8 (2004): 1105–15. http://dx.doi.org/10.1016/j.mri.2004.01.076.

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Rehnitz, Christoph, Marc-André Weber, and Felix Wuennemann. "Imaging of the Knee Following Repair of Focal Articular Cartilage Lesions." Seminars in Musculoskeletal Radiology 22, no. 04 (2018): 377–85. http://dx.doi.org/10.1055/s-0038-1667301.

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AbstractFocal chondral or osteochondral lesions of the knee are common lesions involving either the cartilage layers or the cartilage layers and the subchondral bone. Despite their heterogeneous clinical presentation, they are important risk factors for the premature development of osteoarthritis. Therefore, early detection of osteochondral lesions and focal cartilage defects is crucial. In symptomatic (osteo-)chondral lesions, numerous therapeutic strategies, ranging from conservative treatment to surgical procedures such as marrow stimulation, osteochondral autograft transplantation, or auto

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Accadbled, Franck, Marco Turati, and Mininder S. Kocher. "Osteochondritis dissecans of the knee: Imaging, instability concept, and criteria." Journal of Children's Orthopaedics 17, no. 1 (2023): 47–53. http://dx.doi.org/10.1177/18632521221149054.

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Osteochondritis dissecans of the knee is an idiopathic, focal, subchondral-bone abnormality that can cause instability or detachment of a bone fragment and overlying articular cartilage, with subsequent progression to osteoarthritis. The degree of lesion instability is best assessed by magnetic resonance imaging. Unstable lesions require operative management with fragment fixation. Level of evidence: V.

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Springer, Bernhard, and Friedrich Boettner. "Treatment of Unicompartmental Cartilage Defects of the Knee with Unicompartmental Knee Arthroplasty, Patellofemoral Partial Knee Arthroplasty or Focal Resurfacing." Life 11, no. 5 (2021): 394. http://dx.doi.org/10.3390/life11050394.

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Focal chondral defects are common lesions of the articular cartilage. They are predominantly found on the medial femoral condyle and often progress to osteoarthritis of the knee. Various conservative treatment options are available. The conservative treatment might reduce pain and delay the progress of degenerative processes. However, restoration of the articular cartilage cannot be accomplished. If the conservative treatment fails unicompartmental arthroplasty, patellofemoral joint replacement or focal resurfacing are reasonable options to postpone total knee arthroplasty. A careful patient s

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Guillén-García, Pedro, Isabel Guillén-Vicente, Elena Rodríguez-Iñigo, et al. "Cartilage Defect Treatment Using High-Density Autologous Chondrocyte Implantation (HD-ACI)." Bioengineering 10, no. 9 (2023): 1083. http://dx.doi.org/10.3390/bioengineering10091083.

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Hyaline cartilage’s inability to self-repair can lead to osteoarthritis and joint replacement. Various treatments, including cell therapy, have been developed for cartilage damage. Autologous chondrocyte implantation (ACI) is considered the best option for focal chondral lesions. In this article, we aimed to create a narrative review that highlights the evolution and enhancement of our chondrocyte implantation technique: High-Density-ACI (HD-ACI) Membrane-assisted Autologous Chondrocyte Implantation (MACI) improved ACI using a collagen membrane as a carrier. However, low cell density in MACI r

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Longo, Umile Giuseppe, Stefano Petrillo, Edoardo Franceschetti, Alessandra Berton, Nicola Maffulli, and Vincenzo Denaro. "Stem Cells and Gene Therapy for Cartilage Repair." Stem Cells International 2012 (2012): 1–9. http://dx.doi.org/10.1155/2012/168385.

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Cartilage defects represent a common problem in orthopaedic practice. Predisposing factors include traumas, inflammatory conditions, and biomechanics alterations. Conservative management of cartilage defects often fails, and patients with this lesions may need surgical intervention. Several treatment strategies have been proposed, although only surgery has been proved to be predictably effective. Usually, in focal cartilage defects without a stable fibrocartilaginous repair tissue formed, surgeons try to promote a natural fibrocartilaginous response by using marrow stimulating techniques, such

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Shim, Dong-Woo, Yeokgu Hwang, Yoo Jung Park, Jin Woo Lee, and Seung Hwan Han. "Detection of Tram Track Lesion in the Ankle Joint; A Comparative Study of Magnetic Resonance Imaging with Ankle Arthroscopy." Foot & Ankle Orthopaedics 2, no. 3 (2017): 2473011417S0003. http://dx.doi.org/10.1177/2473011417s000371.

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Category: Ankle, Arthroscopy Introduction/Purpose: Tram track lesion in the ankle joint has been occasionally found during the ankle arthroscopy and there has been few studies relating the pathophysiology, diagnostic method and treatment of the lesion. This study aimed to show the effectiveness of magnetic resonance imaging (MRI) for detection of tram track lesion in the ankle joint comparing with ankle arthroscopy. Methods: We retrospectively assessed 175 ankles in 170 patients with anterior bony impingement syndrome in the ankle who underwent arthroscopic surgery between January 2013 and Jul

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Rodríguez-Fontán, Francisco, and Cecilia Pascual-Garrido. "Hidrogeles de polimerización in situ para la regeneración de cartílago articular. [In-situ-forming hydrogels for articular cartilage repair]." Revista de la Asociación Argentina de Ortopedia y Traumatología 84, no. 3 (2019): 296–308. http://dx.doi.org/10.15417/issn.1852-7434.2019.84.3.956.

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Una significativa cantidad de adultos jóvenes activos sufre lesiones condrales focales. Estas lesiones, si no se tratan, pueden progresar hacia la artrosis, que es una de las principales enfermedades musculoesqueléticas debilitantes y de gran carga económica que afectan a toda sociedad. Pese a los tratamientos quirúrgicos disponibles para la reparación de defectos condrales focales sintomáticos que mejoran la calidad de vida a mediano plazo, hay un mayor riesgo de progresión hacia la artrosis prematura. Los tratamientos biológicos (células madre, bioingeniería tisular) han avanzado a grandes p

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Book chapters on the topic "Focal Osteoarthritic Cartilage Lesions"

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Minas, Tom. "Autologous Chondrocyte Implantation in the Osteoarthritic Knee." In Articular Cartilage Lesions. Springer New York, 2004. http://dx.doi.org/10.1007/978-0-387-21553-2_11.

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Gillogly, Scott D., and Mats Brittberg. "Autologous Chondrocyte Implantation for Focal Chondral Lesions." In Articular Cartilage Lesions. Springer New York, 2004. http://dx.doi.org/10.1007/978-0-387-21553-2_10.

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Bardos, Tamas. "Pure Cartilage-Based Repair Modalities of Focal Cartilage Lesions." In Developing Insights in Cartilage Repair. Springer London, 2013. http://dx.doi.org/10.1007/978-1-4471-5385-6_18.

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Clunie, Gavin. "Osteonecrosis, osteochondrosis, and osteochondritis dissecans." In Oxford Textbook of Medicine, edited by Cyrus Cooper. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198746690.003.0470.

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This chapter examines the bone conditions of osteonecrosis, osteochondrosis, and osteochondritis dissecans. Osteonecrosis is ischaemia of bone caused by a range of conditions, including trauma, which cause intravascular or extravascular obstruction of blood flow to bone. Many cases are associated with pro-thrombotic conditions. Osteonecrosis can be asymptomatic, but if progressive often leads to secondary (adjacent) joint destruction. Diagnosis is made by magnetic resonance imaging. Aside from treatment of any underlying cause, treatment options include analgesics, vasodilators, and surgery. T

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Conference papers on the topic "Focal Osteoarthritic Cartilage Lesions"

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Yildirim, Gokce, Sally Arno, Ekaterina Khmelnitska, and Peter S. Walker. "MRI Analysis of Femoral Cartilage Thickness in Early Osteoarthritis Knee Patients for Uni-Condylar Knee Potential." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-204220.

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Over the past several decades, Magnetic Resonance Imagining has become a standard in cartilage thickness analysis (Gray 2008, Potter 2006). However, MRI analysis has not been used to indicate patients with early osteoarthritic (OA) cartilage changes for early intervention procedures (EIP) such as grafts or minimally-invasive unicondylar knee replacements. The objective of this study is to examine the viability of using MRI to identify early osteoarthritis of articular cartilage and identify the affected areas in a clinical setting. Based on the results of studies previously conducted in this l

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Roach, Brendan L., Andrea R. Tan, Aaron M. Stoker, et al. "Fabrication of Tissue-Engineered Cartilage Grafts With Anatomic Surface Contours for Repair of Large Focal Defects." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14657.

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Articular cartilage exhibits a poor healing response to injury that necessitates surgical intervention to repair or replace damaged tissue. Treatment options, however, are dependent on the location and size of the defect site. For small focal defects (<2 cm 2), microfracture is the primary method of treatment [8] despite the production of biologically inferior cartilage. For lesions greater than 10 cm 2 where the articular cartilage loss and morphology of the condyle is distorted, a fresh osteoarticular allograft is most likely to succeed [3], while posing a significant surgical challenge r

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Saied, Laugier, Bovo, et al. "Experimental osteoarthritic articular cartilage: in vitro visualization of lesions and three-dimensional surface reconstruction using 50 MHz ultrasound microscope." In Proceedings of IEEE Ultrasonics Symposium ULTSYM-94. IEEE, 1994. http://dx.doi.org/10.1109/ultsym.1994.401869.

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Takai, Erica, X. Edward Guo, Helen H. Lu, et al. "Strategy for Tissue Engineering of Osteochondral Constructs." In ASME 2002 International Mechanical Engineering Congress and Exposition. ASMEDC, 2002. http://dx.doi.org/10.1115/imece2002-33595.

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Damage to articular cartilage is a common condition affecting the joints of millions of people. This is a major problem considering the poor regenerative capacity of adult articular cartilage and the disability and pain that accompanies these injuries [13]. There exists a range of options that have been applied in clinical practice, with variable degrees of success, for repair of focal lesions and damage of the articular surface, including tissue adhesives [1,6,11,12,18], enzymatic treatments [8] and laser solder welding [21], autograft cell/tissue transfer via osteoperiosteal grafts [17], ost

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