Academic literature on the topic 'Freund's complete adjuvant-induced arthritis'

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Journal articles on the topic "Freund's complete adjuvant-induced arthritis"

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Chenchula, Santenna. "Anti-arthritic efficacy of Bombax ceiba ethanolic extract in a murine model for rheumatoid arthritis using in vivo, in vitro and radiological analysis." Bioinformation 19, no. 8 (2023): 833–39. http://dx.doi.org/10.6026/97320630019833.

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Rheumatoid arthritis (RA) is a multisystem autoimmune disease that causes discomfort, synovial membrane inflammation, peripheral joint inflammation, morning stiffness, articular tissue loss, and restricted joint movement. In the present study, we aim to explore the anti-arthritic efficacy of Bombax ceiba ethanolic extract in a Freund's Complete Adjuvant-induced arthritis, in murine model. The hot soxhlet method was used to extract dried aerial components of Bombax ceiba using an ethyl alcohol: water (70:30) ratio. Bombax ceiba ethanolic extract at two doses of 200 and 400 mg/kg was investigate
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Sabale, Ajay Sunil, Anjali Sunil Sabale, Gajendra Kale, Arati Machale, H. V. Kamble, and Supriya Hambir. "To Carry Out Anti-Arthritic Activity of Combination of Quercetin and Curcumin Using FCA (Freund’s Complete Adjuvant) Induced Arthritis in Laboratory Rats." Journal of Drug Delivery and Therapeutics 14, no. 3 (2024): 80–87. http://dx.doi.org/10.22270/jddt.v14i3.6463.

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To investigate anti-arthritic activity of Quercetin and Curcumin in Freund's complete adjuvant (FCA)-induced arthritis in rats. AA was induced by injecting with Freund's complete adjuvant (FCA). Rats were randomly divided into six groups with 10 mice in each group: (1) Normal group (saline), (2) Vehicle control, (3) Leflunomide (LF, 10 mg/kg), (4) Curcumin (80), (5) Quercetin (40), (6) Curcumin (80) + Quercetin (40). Male SD rats were subjected to treatment with Lut at 10 mg/kg from days 18 to 24 after immunization. Arthritic scores, tumor necrosis factor-alpha (TNF-α), interleukin-1 (IL-1), p
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Liu, Yan-li, Hai-ming Lin, Rong Zou, et al. "Suppression of complete Freund's adjuvant-induced adjuvant arthritis by cobratoxin." Acta Pharmacologica Sinica 30, no. 2 (2009): 219–27. http://dx.doi.org/10.1038/aps.2008.20.

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Zhang, Maoquan, Baolong Liu, and Zonghui Ji. "Effect of Wu-Wei-Gui-Shao decoction on complete Freund's adjuvant-induced arthritis rats." Tropical Journal of Pharmaceutical Research 19, no. 9 (2020): 1977–83. http://dx.doi.org/10.4314/tjpr.v19i9.25.

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Purpose: To investigate the anti-rheumatic potential of Wu-Wei-Gui-Shao decoction (WGD) and its possible mechanism of action.
 Methods: Adjuvant arthritis (AA) rats were established using complete Freund's adjuvant. The rats were then given different doses of WGD (100, 200, and 400 mg/kg, for 28 days). The anti-arthritic effects of WGD were evaluated. Furthermore, the in vitro anti-arthritic effects of WGD and its related mechanisms were also determined in MH7A cells.
 Results: WGD (100 - 400 mg/kg) exhibited significant anti-rheumatic properties after 28 days of treatment, inhibitin
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Kim, Jae-Hyo, Hee-Kee Kim, Yong-Il Park, et al. "Moxibustion at ST36 Alleviates Pain in Complete Freund's Adjuvant-Induced Arthritic Rats." American Journal of Chinese Medicine 34, no. 01 (2006): 57–67. http://dx.doi.org/10.1142/s0192415x06003631.

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This study was to investigate the antinociceptive effects of moxibustion in a complete Freund's adjuvant (CFA)-induced arthritic rat model, and the effects of moxibustion on immunohistochemical changes at the spinal cord level. Moxibustion was applied to the ipsilateral (right) Zusanli (ST36) acupoint to the lesion side for 9 days to CFA-induced arthritic rats. The stepping force was measured as a behavioral test, c-Fos immunohistochemistry, NO production and nNOS Western blots were examined to evaluate antinociceptive effects. Moxibustion at ST36 significantly improved the stepping force in t
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Putri, Dwi Kurnia, and Endang Darmawan. "Analgesic Activity of Chitosan in Arthritis Rats Induced by Complete Freund's Adjuvant (CFA)." PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) 19, no. 1 (2022): 132. http://dx.doi.org/10.30595/pharmacy.v19i1.13842.

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Arthritis is inflammation and pain in joints, often accompanied by stiffness and difficulty to move. The current pain treatment in arthritis is synthetic drugs that have many side effects. Chitosan’s structure similar to that of glucosamine which can be used as anti-arthritis. This study aims to evaluate the analgesic activity of chitosan in arthritic rats. The heat stimulation method with a hot plate at temperature of 55±1oC was utilized. A total of 25 male Sprague Dawley rats, weighing 150-250 g, were fed and given water ad libitum. There were grouped into group I (normal control), group II
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M., TamizhMozhi* D. Nagavalli. "CURATIVE EFFECT OF FORMONOETIN-7-O-Β-D-GLUCOPYRANOSIDE FROM METHANOLIC EXTRACT OF OPERCULINA TURPETHUM IN FREUND'S COMPLETE ADJUVANT INDUCED ARTHRITIS". iajps,csk publications 03, № 11 (2016): 1415–23. https://doi.org/10.5281/zenodo.208204.

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Objective: To investigate the anti arthritic potential of isolated compound Formonoetin-7-O-β-D-glucopyranoside from Methanolic Extract of Operculina turpethum. Methods: F-7-β-D-g was subjected to assess the anti arthritic activity by foot pat thickness, body weight measurement, rheumatoid factor, spleen index score assessment and hematological estimation using a model Complete Freund’s Adjuvant (CFA) induced arthritis in wistar rat. Result: Administration of F-7-β-D-g at the doses of 10, 20, 40, 50 mg/kg b. w. p. o exhibited statistically significant (p < 0.001) inhibition of the edema, rh
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Neeraj, Srivastava, Dashora Nipun, Menaria Jyoti, and Kumar Neeraj. "Evaluation of Anti-inflammatory and Anti-arthritic Activity of Ajmodadi Churna- A Polyherbal Formulation." International Journal of Pharmaceutical and Phytopharmacological Research 6, no. 5 (2016): 72. http://dx.doi.org/10.24896/eijppr.2016651.

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Anti-inflammatory and anti- arthritic activity of aqueous extract of Ajmodadi Churna (AJM) were evaluated by three methods namely, Carrageenan paw edema, Carrageenan induced Air Pouch Model in Rats and Freunds’ complete adjuvant Arthritis. The Carrageenan paw edema was carried out to test the effect of the extract on acute phase of inflammation. Carrageenan induced Air Pouch Model was used for local inflammation and Freunds’ complete adjuvant Arthritis was used for evaluation of chronic inflammation. Results showed that AJM have significant anti-inflammatory activity and Anti-arthritic Activit
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Alghulami, Omar, Ghaith A. Jasim, and Suzan Yousif Jasim. "Effect of Docetaxel on Matrix Metalloproteinase 1 Expression in Freund’s Adjuvant Induced Arthritis." Iraqi Journal of Pharmaceutical Sciences( P-ISSN 1683 - 3597 E-ISSN 2521 - 3512) 33, no. 1 (2024): 163–71. http://dx.doi.org/10.31351/vol33iss1pp163-171.

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Rheumatoid arthritis is an autoimmune disorder that affects the synovial joints. It lead to inflammatory changes occur in synovial tissue, cartilage, bone, and, less frequently, extra-articular structures. Docetaxel, is an anti-neoplastic drug. Methotrexate is a treatment for early-stage rheumatoid arthritis but have 30% failure in treatment within the first year due to resistance or side effects. Matrix metalloproteinase 1 is the proteinase primarily in charge of the irreversible degradation of cartilage, bone, and tendons in the joints, which are induced by cytokines. This study aims to eval
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Lan, Zhou, Meng Wei, Lvyi Chen, Guangjing Xie, Xiao Liu, and Xiuqiao Zhang. "Role of Sinomenine on Complete Freund's Adjuvant-Induced Arthritis in Rats." IUBMB Life 68, no. 6 (2016): 429–35. http://dx.doi.org/10.1002/iub.1499.

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Dissertations / Theses on the topic "Freund's complete adjuvant-induced arthritis"

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Gomes, Raquel Pinheiro. "Atividade física no tratamento de artrite induzida por adjuvante de Freund : efeitos na nocicepção, edema e migração celular." Universidade do Estado de Santa Catarina, 2008. http://tede.udesc.br/handle/handle/382.

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Made available in DSpace on 2016-12-06T17:07:14Z (GMT). No. of bitstreams: 1 raquel.pdf: 914060 bytes, checksum: a82d971c1700ac78e8cc69f342332599 (MD5) Previous issue date: 2008-03-06<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>Physical activity is thought to be beneficial to arthritis, delaying disability and/or improving joint function. The aim of the present study was to evaluate the effects of exercise on nociception, edema and cell migration in two groups of rats with CFA-induced arthritis, as well as verify whether the possible endogenous liberation of corticoids
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Barszczyk, Andrew. "A Peptide Comprising the Src-interacting Domain of NADH Dehydrogenase Subunit 2 Alleviates Complete Freund's Adjuvant-induced Allodynia in Rats." Thesis, 2010. http://hdl.handle.net/1807/25421.

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Inflammatory and neuropathic pains arise in part from sensitization at nociceptive synapses in the spinal cord. Activity-dependent signaling cascades converge onto the tyrosine kinase Src, which participates in augmenting the function of N-methyl-D-aspartate receptors (NMDARs) and thus potentiates the nociceptive system. Src is capable of these effects because it is anchored to the NMDAR complex via an adaptor protein called NADH dehydrogenase subunit 2 (ND2). There is evidence that this interaction occurs between amino acids 40-49 of Src and amino acids 310-321 of ND2. I have determined that
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Huang, Fang-Chuen, and 黃方君. "The Comparative Effects of High- and Low-fluence Low-levelLaser Therapy in Rats with Complete Freund''sAdjuvant-induced Arthritis." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/t9g8p4.

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碩士<br>中國醫藥大學<br>物理治療學系復健科學碩士班<br>101<br>Background and Purpose: Rheumatoid arthritis (RA) is a chronic, inflammatory and systemic autoimmune disease that leads to progressive synovitis and cartilage destruction. This chronic inflammatory process stimulates proliferation of fibroblast-like synoviocytes, enhances activities of tumor necrosis factor-α (TNF-α) and matrix metalloproteinase-3 (MMP3), and then leads to cartilage destruction. Low-level laser therapy (LLLT) is the proven and recommended intervention for managing RA on alleviating pain. But the effective fluence of LLLT on prevention of
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Conference papers on the topic "Freund's complete adjuvant-induced arthritis"

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Roslida, A. H., M. B. Baizura, and K. Huzwah. "Acmella uliginosa (Sw) Cass. leaves extracts mitigate Complete-Freund Adjuvant (CFA) induced arthritis in rats via angiogenesis suppression." In GA – 69th Annual Meeting 2021, Virtual conference. Georg Thieme Verlag, 2021. http://dx.doi.org/10.1055/s-0041-1736895.

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Kucikarova, Liubov, Khasan Kayumov, Sevara Berdiyorova, Rashid Achilov, Nurshat Murtazaeva, and Shokhlakhon Jurakulov. "The metabolic connection between diabetes mellitus and autoimmune hypothyroidism." In "Fiziologia şi sănătatea", congresul fiziologilor. Bulletin of the Academy of Sciences of Moldova. Medical Sciences, 2025. https://doi.org/10.52692/cfzl2024.30.

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It is supposed that there is a connection between diabetes mellitus (DM) and autoimmune hypothyroidism (AIH). The aim of this study was to compare some biochemical blood parameters in experimental DM and AIH. The experiments were carried out on outbred white rats. DM was induced by feeding animals with a high-fat diet and a single injection of streptozotocin (35 mg/kg). AIH was induced by three subcutaneous injections of thyroglobulin (100μ/rat) and Freund's adjuvant. For the first injection complete adjuvant, for the second and third treatments, incomplete adjuvant was used on the sixth and s
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Nakamori, S., N. Miyajima, S. Hyuga, et al. "Therapeutic and analgesic effects of ephedrine alkaloids-free Ephedra Herb extract on complete Freud’s adjuvant-induced arthritis model mouse." In 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP. © Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-3399686.

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