Academic literature on the topic 'Fused-ring Compounds'

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Journal articles on the topic "Fused-ring Compounds"

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M., Deepak, Sharan A., Srinivasan P., Shahi K., and V. Srinivasan K. "Solid state conductance in fused ring aromatic compounds." Journal of Indian Chemical Society Vol. 77, Jul 2000 (2000): 349–51. https://doi.org/10.5281/zenodo.5867635.

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Magadh Mahila College, Patna-800 001, India Department of Chemistry, Patna University, Patna-800 005, India <em>Manuscript received 3 February 1999, revised 5 November 1999, accepted 3 March 2000</em> Solid state conductance in aromatic fused ring compounds such as naphthalene, anthracene and phenanthrene exhibits space charge&nbsp;limitations. The measurements point to the presence of traps exponentially dibtributed over a wide energy range. Currents&nbsp;are found to vary with temperature in these samples exhibiting low activation energies. The activation energy decreases from naphthalene&nb
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Ozer, Erdem Kamil, Miyase Gozde Gunduz, Ahmed El-Khouly, et al. "Synthesis of fused 1,4-dihydropyridines as potential calcium channel blockers." Turkish Journal of Biochemistry 43, no. 6 (2017): 578–86. http://dx.doi.org/10.1515/tjb-2016-0247.

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AbstractObjectiveThe aim of this study was to synthesize ten 1,4-dihydropyridine (DHP) derivatives in which substituted cyclohexane rings were fused to the DHP ring and to determine how different ester groups and the benzoyl substituent introduced in 4-phenyl ring affected their calcium channel blocking activity.MethodsA microwave-assisted one-pot method was applied for the synthesis of compound1–5according to a modified Hantzsch reaction. The benzoyl moiety was introduced in the 4-phenyl ring of these dihydropyridines by refluxing with benzoyl chloride in acetone in the presence of anhydrous
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Zheng, Wei, Yuan Zhao, Wen‐Hao Zhuang, et al. "Phthalorubines: Fused‐Ring Compounds Synthesized from Phthalonitrile." Angewandte Chemie 130, no. 47 (2018): 15610–15. http://dx.doi.org/10.1002/ange.201807281.

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Zheng, Wei, Yuan Zhao, Wen‐Hao Zhuang, et al. "Phthalorubines: Fused‐Ring Compounds Synthesized from Phthalonitrile." Angewandte Chemie International Edition 57, no. 47 (2018): 15384–89. http://dx.doi.org/10.1002/anie.201807281.

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Teymouri, Mahshid, Anna Pietrzak, and Paulina Bartos. "(Hetero)Arene Ring-Fused [1,2,4]Triazines." Molbank 2024, no. 2 (2024): M1824. http://dx.doi.org/10.3390/m1824.

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Synthetic access to a five (hetero)arene ring-fused 3-phenyl[1,2,4]triazines is described. The resulting compounds were characterized via 1H and 13C NMR, IR, UV–vis spectroscopy and HRMS. The structure of 3-phenyl[1,2,4]triazino[5,6-c]quinoline was unambiguously confirmed by single crystal XRD.
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Fang, Xiangdong, Hong Yang, Jeff W. Kampf, Mark M. Banaszak Holl, and Arthur J. Ashe. "Syntheses of Ring-Fused B−N Heteroaromatic Compounds." Organometallics 25, no. 2 (2006): 513–18. http://dx.doi.org/10.1021/om058048e.

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Kündig, E. Peter, Alejandro Bellido, Krishna P. Kaliappan, Andrew R. Pape, and Sylvie Radix. "Efficient Access to Fused Ring Compounds via Dearomatization/Ring-Closing Metathesis." Synlett, no. 15 (2003): 2407–9. http://dx.doi.org/10.1055/s-2003-43330.

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Yin, Zhao-Kun, Zi-Ming Feng, Jian-Shuang Jiang, Xu Zhang, Pei-Cheng Zhang, and Ya-Nan Yang. "New diterpenoid quinones derived from Salvia miltiorrhiza and their cytotoxic and neuroprotective activities." RSC Advances 10, no. 24 (2020): 14235–42. http://dx.doi.org/10.1039/d0ra02022b.

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A new tanshinone derivative, which possesses an unusual 6/6/5/6 fused-ring skeleton together with 4 new five-membered lactone benzohexa-membered ring compounds and 3 new carboxyl substituted 5,5-spiroketal compounds, were isolated from dried rhizomes of Salvia miltiorrhiza.
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Aitken, R., and Alasdair Garnett. "Versatile Pyrolytic Synthesis of Fused Polycyclic Heteroaromatic Compounds." Synthesis 49, no. 22 (2017): 4955–77. http://dx.doi.org/10.1055/s-0036-1588586.

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Thirty-six new stabilised phosphonium ylides designed to undergo thermal loss of Ph3PO and radical domino cyclisation have been prepared and are generally found to undergo the desired reaction under flash vacuum pyrolysis conditions at 850 °C. A wide range of ­tetra- and pentacyclic fused-ring heterocycles, many previously unknown, are thus formed in moderate to high yield in a single step. By using suitably substituted starting materials, substituents such as CH3 and Cl can be installed at various positions in the products. The method has also been demonstrated in a combinatorial mode to gene
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Panda, Niranjan, Irshad Mattan, Subhadra Ojha, and Chandra Shekhar Purohit. "Synthesis of medium-sized (6–7–6) ring compounds by iron-catalyzed dehydrogenative C–H activation/annulation." Organic & Biomolecular Chemistry 16, no. 42 (2018): 7861–70. http://dx.doi.org/10.1039/c8ob01496e.

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Dissertations / Theses on the topic "Fused-ring Compounds"

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Tatsuya, Nakano. "Synthesis and Functionalization of Fused Aromatic Ring-layered Compounds." 京都大学 (Kyoto University), 2015. http://hdl.handle.net/2433/199330.

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Naoe, Saori. "Synthesis of Fused-Ring Compounds through Gold-Catalyzed Cascade Reactions." 京都大学 (Kyoto University), 2016. http://hdl.handle.net/2433/215495.

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Murray, Lorna. "New gas-phase cascade reactions of stabilising phosphorus ylides leading to ring-fused indoles and quinolines." Thesis, University of St Andrews, 2010. http://hdl.handle.net/10023/971.

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Synthesis and flash vacuum pyrolysis (FVP) of stabilised phosphorus ylides containing an o-amino functionalised benzene ring has been examined for the first time. Model studies using N-methyl-N-tosyl and N-mesyl-N-methyl ylides showed that the ylides could be prepared, although yields were variable, and had the expected spectroscopic properties. Upon FVP, however, the expected loss of Ph₃PO and the sulfonyl group was accompanied by unexpected transfer of the reactive site from nitrogen to carbon giving 3- substituted quinolines rather than the expected indole products. Moving to ylides with an
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Takuya, Matsumoto. "Development of Novel Conjugated Compounds Based on Characteristics of Gallium Element." 京都大学 (Kyoto University), 2015. http://hdl.handle.net/2433/199329.

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Eschenbrenner-Lux, Vincent [Verfasser], Herbert [Akademischer Betreuer] Waldmann, and Frank [Gutachter] Schulz. "Development of cascade reactions to ring fused quinolizines for the synthesis of a natural product inspired compound collection / Vincent Eschenbrenner-Lux. Betreuer: Herbert Waldmann. Gutachter: Frank Schulz." Dortmund : Universitätsbibliothek Dortmund, 2014. http://d-nb.info/1107197309/34.

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Aderibigbe, Blessing Atim. "Isomerisation and ring closing metathesis reactions towards benzo-fused heterocyclic compounds." Thesis, 2006. http://hdl.handle.net/10539/1556.

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Student Number : 0410864E - MSc dissertation - School of Chemistry - Faculty of Science<br>The aim of the project described in this dissertation is to explore the application of ring closing metathesis (RCM) to the synthesis of 6-, 7-, 8- and 9-membered N,N-, N,O- and O,O-benzo-fused heterocyclic compounds which are interesting structural motifs in medicinal chemistry. In recent times, their structures have been widely used as molecular scaffolds. Some of these heterocycles have been identified as antitumour agents, antibiotics and anti-HIV agents. In our laboratories, a variety of 6-
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Bailey, Timothy Samuel. "Synthesis of fused medium-ring heterocycles by the rearrangement of quaternary ammonium derivatives." Thesis, 1994. https://eprints.utas.edu.au/18986/1/whole_BaileyTimothySamuel1994_thesis.pdf.

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The general aim of this study was to develop new modes of access to benzfused medium-ring heterocycles. The approach adopted was to utilise the rearrangements, with concurrent ring expansion, of heterocyclic quaternary ammonium N-ylides and N-oxides. Of particular interest were new applications of the [2,3] rearrangements of these systems. Base promoted [2,3] sigmatropic rearrangement of 1-viny1-2- ethoxycarbonylmethyl-1,2,3,4-tetrahydroisoquinolinium salts at room temperature in acetonitrile afforded functionalised 2,3,4,5-tetrahydro-1H-3-benzazonine derivatives, as mixtures of the o
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Taylor, Rebecca M. "Exploiting ring-fused gem-dibromocyclopropanes in novel C-C bond forming reactions : applications to the synthesis of natural product frameworks." Phd thesis, 2005. http://hdl.handle.net/1885/146671.

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Hsu, Wen-Chi, та 許文綺. "Relative Binding Free Energy Computation of GSK-3β Kinase-Ligand Complexes Using Thermodynamic Integration MD Simulation: Compounds with Pyrazolo-Pyridazin Fused Ring". Thesis, 2015. http://ndltd.ncl.edu.tw/handle/565ht6.

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碩士<br>國立臺灣師範大學<br>化學系<br>103<br>Glycogen synthase kinase 3 (GSK-3) is a serine/threonine kinase that plays an important role in the pathogenesis of Alzheimer's disease (AD). It was postulated that when GSK-3β kinase’s activity is too high, it over-phosphorylates tau protein and causes AD.Inhibition of GSK-3βkinase would provide therapeutic effect in alleviated and/or cure AD.In the present study, we used thermodynamic integration molecular dynamics (TI-MD) simulation to calculate protein-ligand binding free energy to aid in design of GSK-3β inhibitors. First, we computed the affinity of analog
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Books on the topic "Fused-ring Compounds"

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Wade, Anthony Eugene. Some fluorinations of fused-ring compounds containing nitrogen. University of Birmingham, 1985.

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Lednicer, Daniel. The organic chemistry of drug synthesis. Wiley, 1995.

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Lednicer, Daniel. The organic chemistry of drug synthesis. Wiley, 1990.

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Parker, Philip M. The 2007 Import and Export Market for Heterocyclic Compounds with a Phenothiazine Ring-System but Not Further Fused in India. ICON Group International, Inc., 2006.

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Parker, Philip M. The World Market for Heterocyclic Compounds with a Phenothiazine Ring-System but Not Further Fused: A 2007 Global Trade Perspective. ICON Group International, Inc., 2006.

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The World Market for Heterocyclic Compounds with a Phenothiazine Ring-System but Not Further Fused: A 2004 Global Trade Perspective. Icon Group International, Inc., 2005.

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Parker, Philip M. The 2007 Import and Export Market for Heterocyclic Compounds with a Phenothiazine Ring-System but Not Further Fused in China. ICON Group International, Inc., 2006.

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Parker, Philip M. The 2007 Import and Export Market for Heterocyclic Compounds with a Phenothiazine Ring-System but Not Further Fused in United States. ICON Group International, Inc., 2006.

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Parker, Philip M. The 2007 Import and Export Market for Heterocyclic Compounds with Nitrogen Hetero-Atom(s) Only, Containing a Quinoline or Isoquinoline Ring-System Not Further Fused in China. ICON Group International, Inc., 2006.

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The World Market for Heterocyclic Compounds with Nitrogen Hetero-Atom(s) Only, Containing a Quinoline or Isoquinoline Ring-System Not Further Fused: A 2004 Global Trade Perspective. Icon Group International, Inc., 2005.

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Book chapters on the topic "Fused-ring Compounds"

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"Fused 3-Membered Ring Systems." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470186732.ch2.

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"Fused 4-Membered Ring Systems." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470186732.ch3.

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"Fused 5/5 Ring Systems." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470186732.ch4.

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Chandrashekharappa, Sandeep, Subrata Barick, and Kaustav Dhara. "Biological Relevance of Five Membered Fused Heterocycle Imidazothiazole." In Advances in Bioinformatics and Biomedical Engineering. IGI Global, 2024. http://dx.doi.org/10.4018/979-8-3693-7520-4.ch001.

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Heterocyclic compounds are essential in the metabolism of all living cells, and most nitrogen-containing fused heterocyclic compounds with five-membered rings are biologically active. Nitrogen and sulphur-containing heteroaromatic compounds, such as imidazothiazoles and their derivatives, are acknowledged for their biological activity and substantial contributions to medicinal chemistry. Imidazothiazoles are defined by their fused bicyclic structure, merging an imidazole ring (a five-membered ring with two non-adjacent nitrogen atoms) with a thiazole ring (a five-membered ring containing both
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AIZAWA, HIROYASU. "Phenyl Ring Fused Five-Membered Heterocyclic Compounds." In Metabolic Maps of Pesticides. Elsevier, 1989. http://dx.doi.org/10.1016/b978-0-12-046481-4.50017-7.

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"Fused 6/7 and Larger Ring Systems." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470186749.ch10.

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"Fused 5/7 and Larger Ring Systems." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470186749.ch5.

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Hatvate, Navnath Tulshiram, Rutuja Rambhau Ukhade, and Hemantkumar Akolkar. "Synthesis, Properties, and Biological Activity of Benzothiadiazine." In Advances in Bioinformatics and Biomedical Engineering. IGI Global, 2024. http://dx.doi.org/10.4018/979-8-3693-7520-4.ch010.

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Heterocyclic compounds are ubiquitous in biologically active compounds, including many drugs. Benzothiadiazine is a class of sulphur and nitrogen-containing heterocyclic compounds comprised of a benzene ring fused with thiadiazine. Benzothiadiazine rings appear in many marketed drugs, such as bendroflumethiazide, chlorothiazide, cyclothiazide, hydrochlorothiazide, and diazoxide, which are popularly known for their diuretic activity. The ring has diverse pharmacological activity, including anti-cancer, antifungal, antimicrobial, anthelmintic, hypolipidaemic, and antidiabetic activity. This chap
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Hatvate, Navnath Tulshiram, Trupti Sahebrao Shevkar, and Hemantkumar Akolkar. "Thienopyrimidines Exploring the Chemistry and Bioactivity." In Advances in Bioinformatics and Biomedical Engineering. IGI Global, 2024. http://dx.doi.org/10.4018/979-8-3693-7520-4.ch008.

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Thienopyrimidine is a heterocyclic compound with a thiophene ring fused to a pyrimidine ring. Due to their diverse properties and applications, these compounds are found in pharmaceuticals, agrochemicals, and materials science. The potential biological activities of thienopyridine derivatives have been investigated and utilized in medicinal chemistry. It also has diverse pharmacological activity, including anti-Alzheimer, anti-cancer, anti-fungal, anti-microbial, anthelmintic, hypolipidaemic, and anti-diabetic activity. Many commercially available drugs, including pictilisib, relugolix, and ol
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Istanbullu, Huseyin, Gulsah Bayraktar, and Merve Saylam. "Fused Pyridine Derivatives: Synthesis and Biological Activities." In Chemistry with Pyridine Derivatives [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.107537.

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Five-membered heteroaromatic ring fused pyridine derivatives are of increasing interest in drug design and medicinal chemistry. The structural similarity of many drugs (especially antiviral and anticancer ones) with DNA bases such as adenine and guanine is a key factor to explain their effectiveness. Apart from these, it is also found in the structures of substances with antituberculosis, antibacterial, antifungal, anti-inflammatory, and antimalarial activities. Another advantage of this group of compounds is their positive contribution to solubility, polarity, lipophilicity, and hydrogen bond
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Conference papers on the topic "Fused-ring Compounds"

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Ali, Zaineb, Widad Alani, Suzan ALAMDAR, Muhamed Abbas, and Muntadher Alrabeeah. "Isolation of Esculetin and Umbelliferone from Viola Odorata Cultivated in Iraq." In 5th International Conference on Biomedical and Health Sciences. Cihan University-Erbil, 2024. http://dx.doi.org/10.24086/biohs2024/paper.1435.

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Abstract—Viola odorata is a species of the viola family, may be found naturally occurring over Europe and Asia. This little plant is tough and perennially herbaceous. It's also known as sweet violet and English violet. There are several medicinal uses for this flowering plant, including anticancer, antibacterial, inflammation., antioxidant activity and antipyretic activity. The phytochemical studies of Viola odorata different parts resulted in identification and isolation of different chemical constituents such as Coumarins, caffeic acid, methyl salicylate, flavonoids (Quercetin, kaempferol),
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