Relevant bibliographies by topics / GE-180

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'GE-180'

Author: Grafiati
Published: 2 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "GE-180"

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Boutin, Hervé, Katie Murray, Jesus Pradillo, et al. "[18F]GE-180: a novel TSPO radiotracer compared to [11C]PK11195 in a preclinical model of stroke." Eur J Nucl Med Mol Imaging 42, no. 3 (2014): 503–11. https://doi.org/10.1007/s00259-014-2939-8.

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PURPOSE: Neuroinflammation plays a critical role in various neuropathological conditions, and hence there is renewed interest in the translocator protein (TSPO) as a biomarker of microglial activation and macrophage infiltration in the brain. This is reflected in the large amount of research conducted seeking to replace the prototypical PET radiotracer 11C-R-PK11195 with a TSPO ligand with higher performance. Here we report the in vivo preclinical investigation of the novel TSPO tracer 18F-GE-180 in a rat model of stroke. METHODS: Focal cerebral ischaemia was induced in Wistar rats by 60-min o
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Hellberg, Sanna, Heidi Liljenbäck, Olli Eskola, et al. "Positron Emission Tomography Imaging of Macrophages in Atherosclerosis with 18F-GE-180, a Radiotracer for Translocator Protein (TSPO)." Contrast Media & Molecular Imaging 2018 (2018): 1–11. http://dx.doi.org/10.1155/2018/9186902.

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Intraplaque inflammation plays an important role in the progression of atherosclerosis. The 18 kDa translocator protein (TSPO) expression is upregulated in activated macrophages, representing a potential target to identify inflamed atherosclerotic plaques. We preclinically evaluated 18F-GE-180, a novel third-generation TSPO radioligand, in a mouse model of atherosclerosis. Methods. Nine hypercholesterolemic mice deficient in low density lipoprotein receptor and apolipoprotein B48 (LDLR−/−ApoB100/100) and six healthy C57BL/6N mice were injected with 10 MBq of 18F-GE-180. Specificity of binding
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Holzgreve, Adrien, Dennis Pötter, Matthias Brendel, et al. "Longitudinal [18F]GE-180 PET Imaging Facilitates In Vivo Monitoring of TSPO Expression in the GL261 Glioblastoma Mouse Model." Biomedicines 10, no. 4 (2022): 738. http://dx.doi.org/10.3390/biomedicines10040738.

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The 18 kDa translocator protein (TSPO) is increasingly recognized as an interesting target for the imaging of glioblastoma (GBM). Here, we investigated TSPO PET imaging and autoradiography in the frequently used GL261 glioblastoma mouse model and aimed to generate insights into the temporal evolution of TSPO radioligand uptake in glioblastoma in a preclinical setting. We performed a longitudinal [18F]GE-180 PET imaging study from day 4 to 14 post inoculation in the orthotopic syngeneic GL261 GBM mouse model (n = 21 GBM mice, n = 3 sham mice). Contrast-enhanced computed tomography (CT) was perf
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Nik Azmi, Nik Nur Ashirah, Thuan Chew Tan, May Yen Ang, Yong Foo Wong, and Yin-Hui Leong. "Monitoring changes in 3-monochloropropanediol, 2-monochloropropanediol, and glycidyl esters of palm olein after repeated deep frying of commercial chicken nuggets." International Food Research Journal 31, no. 6 (2024): 1591–604. https://doi.org/10.47836/ifrj.31.6.17.

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The present work examined the changes in 3-monochloropropanediol ester (3-MCPDE), 2-monochloropropanediol ester (2-MCPDE), and glycidyl ester (GE) in palm olein after repeated deep frying of commercial chicken nugget samples at 160 and 180°C. Free fatty acid (FFA) composition, p-anisidine value (p-AV), and specific extinction at 232 and 268 nm (K232 and K268) were determined. Results indicated that the concentrations of MCPDEs and GE in the frying oil after the fourth frying cycle were higher than the initial concentrations, except for the GE concentration when fried at 180°C. The content of 3
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Buchert, Ralph, Meike Dirks, Christian Schütze, et al. "Reliable quantification of 18F-GE-180 PET neuroinflammation studies using an individually scaled population-based input function or late tissue-to-blood ratio." European Journal of Nuclear Medicine and Molecular Imaging 47, no. 12 (2020): 2887–900. http://dx.doi.org/10.1007/s00259-020-04810-1.

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Abstract Purpose Tracer kinetic modeling of tissue time activity curves and the individual input function based on arterial blood sampling and metabolite correction is the gold standard for quantitative characterization of microglia activation by PET with the translocator protein (TSPO) ligand 18F-GE-180. This study tested simplified methods for quantification of 18F-GE-180 PET. Methods Dynamic 18F-GE-180 PET with arterial blood sampling and metabolite correction was performed in five healthy volunteers and 20 liver-transplanted patients. Population-based input function templates were generate
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Dickens, Alex M., Susanne Vainio, Päivi Marjamäki, et al. "Detection of Microglial Activation in an Acute Model of Neuroinflammation Using PET and Radiotracers 11C-(R)-PK11195 and 18F-GE-180." J Nucl Med. 55, no. 3 (2014): 466–72. https://doi.org/10.2967/jnumed.113.125625.

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It remains unclear how different translocator protein (TSPO) ligands reflect the spatial extent of astrocyte or microglial activation in various neuroinflammatory conditions. Here, we use a reproducible lipopolysaccharide (LPS)-induced model of acute central nervous system inflammation to compare the binding performance of a new TSPO ligand (18)F-GE-180 with (11)C-(R)-PK11195. Using immunohistochemistry, we also explore the ability of the TSPO ligands to detect activated microglial cells and astrocytes. METHODS: Lewis rats (n = 30) were microinjected with LPS (1 or 10 μg) or saline (1 μL
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López-Picón, Francisco, Anniina Snellman, Olli Eskola, et al. "Neuroinflammation appears early and then plateaus in a mouse model of Alzheimer's disease shown by PET imaging." Journal of Nuclear Medecine 59, no. 3 (2017): 509–15. https://doi.org/10.2967/jnumed.117.197608.

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<strong>Abstract</strong> <strong>Rationale:</strong> Neuroinflammation has been associated with different neurological diseases including Alzheimer&#39;s disease (AD). In AD, the translocator protein 18kDa (TSPO) is overexpressed in the activated microglia that surround the &beta;-amyloid plaques. In the current longitudinal study, using a mouse model of AD, we evaluated the association between &beta;-amyloid deposition and neuroinflammation in AD. <strong>Methods:</strong> To monitor the longitudinal changes in &beta;-amyloid deposition and neuroinflammation, we used in vivo PET imaging and
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Vettermann, Franziska J., Stefanie Harris, Julia Schmitt, et al. "Impact of TSPO Receptor Polymorphism on [18F]GE-180 Binding in Healthy Brain and Pseudo-Reference Regions of Neurooncological and Neurodegenerative Disorders." Life 11, no. 6 (2021): 484. http://dx.doi.org/10.3390/life11060484.

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TSPO-PET tracers are sensitive to a single-nucleotide polymorphism (rs6971-SNP), resulting in low-, medium- and high-affinity binders (LABs, MABs and HABS), but the clinical relevance of [18F]GE-180 is still unclear. We evaluated the impact of rs6971-SNP on in vivo [18F]GE-180 binding in a healthy brain and in pseudo-reference tissue in neuro-oncological and neurodegenerative diseases. Standardized uptake values (SUVs) of [18F]GE-180-PET were assessed using a manually drawn region of interest in the frontoparietal and cerebellar hemispheres. The SUVs were compared between the LABs, MABs and HA
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Gold, Lukas, Enio Barci, Matthias Brendel, et al. "The Traumatic Inoculation Process Affects TSPO Radioligand Uptake in Experimental Orthotopic Glioblastoma." Biomedicines 12, no. 1 (2024): 188. http://dx.doi.org/10.3390/biomedicines12010188.

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Background: The translocator protein (TSPO) has been proven to have great potential as a target for the positron emission tomography (PET) imaging of glioblastoma. However, there is an ongoing debate about the potential various sources of the TSPO PET signal. This work investigates the impact of the inoculation-driven immune response on the PET signal in experimental orthotopic glioblastoma. Methods: Serial [18F]GE-180 and O-(2-[18F]fluoroethyl)-L-tyrosine ([18F]FET) PET scans were performed at day 7/8 and day 14/15 after the inoculation of GL261 mouse glioblastoma cells (n = 24) or saline (sh
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Sridharan, Sujata, Francois-Xavier Lepelletier, William Trigg, et al. "Comparative Evaluation of Three TSPO PET Radiotracers in a LPS-Induced Model of Mild Neuroinflammation in Rats." Molecular Imaging & Biology 19 (August 1, 2016): 77–89. https://doi.org/10.1007/s11307-016-0984-3.

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PURPOSE: Over the past 20&nbsp;years, neuroinflammation (NI) has increasingly been recognised as having an important role in&nbsp; many neurodegenerative diseases, including Alzheimer&#39;s disease. As such, being able to image NI non-invasively in patients is critical to monitor pathological processes and potential therapies targeting neuroinflammation. The translocator protein (TSPO) has proven a reliable NI biomarker for positron emission tomography (PET) imaging. However, if TSPO imaging in acute conditions such as stroke provides strong and reliable signals, TSPO imaging in neurodegenerat
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Dissertations / Theses on the topic "GE-180"

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Sridharan, Sujata. "Quantitative analysis of positron emission tomography (PET) with the second generation translocator protein (TSPO) ligand [18F]GE-180." Thesis, University of Manchester, 2016. https://www.research.manchester.ac.uk/portal/en/theses/quantitative-analysis-of-positron-emission-tomography-pet-with-the-second-generation-translocator-protein-tspo-ligand-18fge180(01bdc97f-90f7-4db3-8268-f65e013640ab).html.

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Background: The 18 kDa translocator protein (TSPO), expressed at a low level in the healthy human central nervous system (CNS), is upregulated in inflammatory brain diseases by activated microglia and other immune cells. Using positron emission tomography (PET) radioligands targeting TSPO, it is possible to localise this signal and map the course of microglial activation and its effects on disease progression. Here, a newly developed second generation TSPO PET ligand, [18F]GE-180, was evaluated in different models of preclinical and clinical neuroinflammatory disease. Methods: A preclinical mo
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Brendel, Matthias [Verfasser]. "Molekulare Bildgebung aktivierter Mikroglia in Mausmodellen neurodegenerativer Erkrankungen mittels 18F-GE-180 Translokator Protein Positronen-Emissions-Tomographie / Matthias Brendel." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2020. http://d-nb.info/1225682886/34.

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Unterrainer, Marcus [Verfasser], and Nathalie [Akademischer Betreuer] Albert. "Evaluation der TSPO-Expression bei schubförmig-remittierender multipler Sklerose und high-grade Gliomen mittels [18F]GE-180 Positronen-Emissions-Tomographie / Marcus Unterrainer ; Betreuer: Nathalie Albert." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2019. http://d-nb.info/1194835287/34.

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Xu, Guo-Chang, and 許國昌. "The antitumor and immunostimultory activities of organogermanium (Ge-132) and its effect on activity of alkaline phosphatase in sarcoma 180 bearing mice." Thesis, 1990. http://ndltd.ncl.edu.tw/handle/50443385124801424620.

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Books on the topic "GE-180"

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tong, He miao ka, ed. Er ge 180. Bei fang fu nü er tong chu ban she, 2009.

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Ge, N. N., M. Ė. Ėlʹzesser, and Tatʹi͡ana Karpova. Nikolaĭ Nikolaevich Ge, 1831-1894: K 180-letii͡u so dni͡a rozhdenii͡a. Pinakoteka, 2011.

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Wang, Chenfa. Bingcheng Huizhou hui guan 180 nian: Kua yue san ge shi ji di tuò̀ zhi shi shi. Bing lang yu Hui zhou hui guan, 2003.

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Ji li yuan gong de 18 ge da yuan ze he 180 ge xiao shou duan. Dang dai shi jie chu ban she, 2010.

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Xiang shou mei li de 180 ge jian kang xiao yun dong. Jing pin wen hua shi ye you xian gong si, 2012.

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Jiu xiang yao ge xiao bao bao, qing song bei yun 180 tian. Jiangxi ke xue ji shu chu ban she, 2017.

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HSK 2 Writing Exercise Book - 180+ Pages for Chinese Character Practice: Organized Tian Zi Ge. Independently Published, 2020.

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Pi wei jian kang shuo ming shu: 180 ge pi wei bao jian fang, xiao bing xiao tong yi sao guang. Hebei chu ban chuan mei ji tuan, 2013.

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Book chapters on the topic "GE-180"

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"More complex systems." In The Quantum Classical Theory, edited by Gert D. Billing. Oxford University Press, 2003. http://dx.doi.org/10.1093/oso/9780195146196.003.0009.

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By more complex systems we mean systems containing on the order of hundreds or thousands of atoms, or molecules with less atoms but with “complicated” motions, the latter being the case when considering collisions between polyatomic molecules. In the present chapter we deal with quantum-classical methods for treating energy transfer in collisions involving polyatomic molecules, molecule surface scattering, reactions in polyatomic systems and solution. We will assume that it is possible to construct realistical potential energy surfaces for the systems. Obviously, these surfaces will be of empi
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Nowak, E., H. Neumann, and M. S. Omar. "Heat Capacity of Ag8Ge10P12 from 180 to 550 K." In January. De Gruyter, 1988. http://dx.doi.org/10.1515/9783112485606-013.

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Conference papers on the topic "GE-180"

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Xie, Jin, Hengzhen Cao, Yuluan Xiang, Dajian Liu, and Daoxin Dai. "Uniform Monolithically Integrated Silicon Photonics Optical Receiver Chip for CWDM4." In Optical Fiber Communication Conference. Optica Publishing Group, 2025. https://doi.org/10.1364/ofc.2025.w2a.18.

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We proposed a monolithic high-speed and high-sensitivity optical receiver chip for CWDM4. It integrates an edge coupler, 4-channel add-drop optical filters based on cascaded CMWGs with gradually changing triangular tooth waveguide width and Ge/Si APDs. This design is fabricated by commercial 180-nm SOI CMOS technology, and exhibited outstanding uniformity.
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Gómez Flórez, Pablo Andrés, Alejandro Toro Betancur, John Edison Morales Galeano, and Jeisson Mejía Velásquez. "PAW and GTAW Welding Repair of HP/IP and Generator Rotors of a Steam Turbine for Electric Power Generation." In AM-EPRI 2024. ASM International, 2024. http://dx.doi.org/10.31399/asm.cp.am-epri-2024p0247.

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Abstract This work describes the repair procedure conducted on the High Pressure/Intermediate Pressure (HP/IP) and generator rotors of a 180 MW steam turbine General Electric (GE) - STAG207FA type D11 installed at La Sierra Thermoelectric Power Plant in Puerto Nare, Colombia. A lubricant supply failure at base load caused severe adhesive damage to the shafts in the bearing support areas and a permanent 3.5 mm bow at the HP/IP rotor mid span section, which required a complex intervention. The repair process began with the identification of the rotors manufacturing material through in-situ metal
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Klimcak, C. M., M. Huang, and J. C. Camparo. "Alkali metal consumption by discharge lamps fabricated from GE-180 aluminosilicate glass." In 2015 Joint Conference of the IEEE International Frequency Control Symposium & the European Frequency and Time Forum (FCS). IEEE, 2015. http://dx.doi.org/10.1109/fcs.2015.7138818.

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Jivan, S., G. Villeret, K. Neumannn, J. Slater, and H. Vanbrocklin. "Implementation of [18F]GE-180 for routine production on ORA Neptis Perform Synthesizer®." In WTTC16: Proceedings of the 16th International Workshop on Targetry and Target Chemistry. Author(s), 2017. http://dx.doi.org/10.1063/1.4983543.

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Nelwan, D., M. Unterrainer, DF Fleischmann, et al. "Prognostic value of 18F-GE-180 PET in newly diagnosed IDH-wildtype glioma prior to radiotherapy." In NuklearMedizin 2020. © Georg Thieme Verlag KG, 2020. http://dx.doi.org/10.1055/s-0040-1708176.

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Marotta, Valerio, Giuseppe Macera, Michael Peter Kennedy, and Ettore Napoli. "Comparative analysis of differential colpitts and cross-coupled VCOs in 180 nm Si-Ge HBT technology." In 2016 IEEE International Symposium on Circuits and Systems (ISCAS). IEEE, 2016. http://dx.doi.org/10.1109/iscas.2016.7538883.

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Marotta, Valerio, Giuseppe Macera, Michael Peter Kennedy, and Ettore Napoli. "The low power and wide tuning range advantages of Armstrong VCOs in 180 nm Si-Ge HBT technology." In 2016 27th Irish Signals and Systems Conference (ISSC). IEEE, 2016. http://dx.doi.org/10.1109/issc.2016.7528439.

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Unterrainer, M., DF Fleischmann, F. Vettermann, et al. "TSPO PET, tumour grading and molecular genetics in histologically verified glioma: a correlative 18F-GE-180 PET study." In NuklearMedizin 2019. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1683496.

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Macera, Giuseppe, and Valerio Marotta. "A low close-in phase noise class-C differential clapp VCO topology in 180 nm Si-Ge HBT technology." In 2017 28th Irish Signals and Systems Conference (ISSC). IEEE, 2017. http://dx.doi.org/10.1109/issc.2017.7983600.

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Eberl, S., T. Eriksson, O. Svedberg та ін. "Routine [sup 18]F[sup −] production with 180 μA to 200 μA target beam current on a GE PETtrace 800 cyclotron". У 14TH INTERNATIONAL WORKSHOP ON TARGETRY AND TARGET CHEMISTRY. AIP, 2012. http://dx.doi.org/10.1063/1.4773942.

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