Academic literature on the topic 'Ghost proteins'

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Journal articles on the topic "Ghost proteins"

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Ali, Randa H., Mohamed E. Ali, and Reham Samir. "Production and Characterization of Bacterial Ghost Vaccine against Neisseria meningitidis." Vaccines 11, no. 1 (2022): 37. http://dx.doi.org/10.3390/vaccines11010037.

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Bacterial ghosts (BGS) are empty non-living envelopes produced either genetically or chemically. This study investigated a novel chemical protocol for the production of Neisseria meningitidis ghost vaccine using tween 80 followed by a pH reduction with lactic acid. For our vaccine candidate, both safety and immunogenicity aspects were evaluated. The ghost pellets showed no sign of growth upon cultivation. BGS were visualized by scanning electron microscopy, illustrating the formation of trans-membrane tunnels with maintained cell morphology. Gel electrophoresis showed no distinctive bands of t
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Golan, D. E., C. S. Brown, C. M. Cianci, S. T. Furlong, and J. P. Caulfield. "Schistosomula of Schistosoma mansoni use lysophosphatidylcholine to lyse adherent human red blood cells and immobilize red cell membrane components." Journal of Cell Biology 103, no. 3 (1986): 819–28. http://dx.doi.org/10.1083/jcb.103.3.819.

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Human red blood cells (RBCs) adhere to and are lysed by schistosomula of Schistosoma mansoni. We have investigated the mechanism of RBC lysis by comparing the dynamic properties of transmembrane protein and lipid probes in adherent ghost membranes with those in control RBCs and in RBCs treated with various membrane perturbants. Fluorescence photobleaching recovery was used to measure the lateral mobility of two integral membrane proteins, glycophorin and band 3, and two lipid analogues, fluorescein phosphatidylethanolamine (Fl-PE) and carbocyanine dyes, in RBCs and ghosts adherent to schistoso
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Jawale, Chetan V., Nithiphonh Somsanith, Seong Kug Eo, Sang-Youel Park, and John Hwa Lee. "Evaluation of Salmonella Gallinarum ghost formulated with Montanide™ ISA 70 VG adjuvant as a vaccine against fowl typhoid." Acta Veterinaria Hungarica 63, no. 4 (2015): 401–12. http://dx.doi.org/10.1556/004.2015.038.

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Escherichia coli heat-labile enterotoxin B subunit (LTB) protein is a potent adjuvant. Salmonella Gallinarum ghosts carrying LTB (S. Gallinarum-LTB ghosts) were genetically constructed using a plasmid, pJHL187-LTB, designed for the co-expression of the LTB and E lysis proteins. This study evaluates the immunopotentiating effects of Montanide™ ISA 70 VG on S. Gallinarum-LTB ghost vaccination against fowl typhoid. Five-week-old layer chickens were injected intramuscularly with sterile PBS (non-immunised control, Group A), S. Gallinarum-LTB ghost (Group B) or S. Gallinarum-LTB ghost emulsified wi
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Wooden, Jason M., Greg Finney, Michael MacCoss, and Diana M. Gilligan. "Comprehensive Analysis of Murine and Human RBC Ghost Proteomes." Blood 108, no. 11 (2006): 1569. http://dx.doi.org/10.1182/blood.v108.11.1569.1569.

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Abstract Inherited hemolytic anemia (spherocytosis or elliptocytosis) is one of the most common inherited diseases with an incidence of 1:2500 to 1:5000 in populations of Northern European descent. Mild to severe inherited hemolytic anemias can arise from defects in the red blood cell (RBC) membrane skeleton. Genetic knock-out of various components of this apparatus has led to the creation of mouse models which have contributed significantly to our understanding of these disorders in humans. However, the mouse and human RBC protein complements have not been comprehensively compared. Using newl
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Nunes-Correia, Isabel, João Ramalho-Santos, and Maria C. Pedroso de Lima. "Sendai Virus Fusion Activity as Modulated by Target Membrane Components." Bioscience Reports 18, no. 2 (1998): 59–68. http://dx.doi.org/10.1023/a:1020180109275.

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We have studied the differences between erythrocytes and erythrocyte ghosts as target membranes for the study of Sendai virus fusion activity. Fusion was monitored continuously by fluorescence dequenching of R18-labeled virus. Experiments were carried out either with or without virus/target membrane prebinding. When Sendai virus was added directly to a erythrocyte/erythrocyte ghost suspension, fusion was always lower than that obtained when experiments were carried out with virus already bound to the erythrocyte/erythrocyte ghost in the cold, since with virus prebinding fusion can be triggered
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Yang, Chinglai, Qingyuan Yang, and Richard W. Compans. "Coreceptor-Dependent Inhibition of the Cell Fusion Activity of Simian Immunodeficiency Virus Env Proteins." Journal of Virology 74, no. 13 (2000): 6217–22. http://dx.doi.org/10.1128/jvi.74.13.6217-6222.2000.

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ABSTRACT The cytoplasmic tail (R peptide) sequence is able to regulate the fusion activity of the murine leukemia virus (MuLV) envelope (Env) protein. We have previously shown that this sequence exerts a profound inhibitory effect on the fusion activity of simian immunodeficiency virus (SIV)-MuLV chimeric Env proteins which contain the extracellular and transmembrane domains of the SIV Env protein. Recent studies have shown that SIV can utilize several alternative cellular coreceptors for its fusion and entry into the cell. We have investigated the fusion activity of SIV and SIV-MuLV chimeric
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Hopgood, M. F., S. E. Knowles, and F. J. Ballard. "Proteolysis of N-ethylmaleimide-modified aldolase loaded into erythrocyte ghosts: prevention by inhibitors of calpain." Biochemical Journal 259, no. 1 (1989): 237–42. http://dx.doi.org/10.1042/bj2590237.

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1. When rabbit muscle aldolase labelled with tritium and inactivated by N-ethylmaleimide (NEM) was loaded into erythrocyte ghosts, significant proteolysis of the loaded protein occurred. The major product of this proteolysis, separated by electrophoresis under dissociating conditions, was found to be approx. 2 kDa smaller than the parent protein. 2. Proteolysis was detectable during erythrocyte ghost loading at 0 degrees C, reaching a plateau after approx. 12 min. Subsequent incubation at 37 degrees C to allow resealing of the ghosts resulted in additional proteolysis, and up to 20% of the loa
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Turrini, F., A. Naitana, L. Mannuzzu, G. Pescarmona, and P. Arese. "Increased red cell calcium, decreased calcium adenosine triphosphatase, and altered membrane proteins during fava bean hemolysis in glucose-6- phosphate dehydrogenase-deficient (Mediterranean variant) individuals." Blood 66, no. 2 (1985): 302–5. http://dx.doi.org/10.1182/blood.v66.2.302.302.

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Abstract RBCs from four glucose-6-phosphate dehydrogenase (G6PD)-deficient (Mediterranean variant) subjects were studied during fava bean hemolysis. In the density-fractionated RBC calcium level, Ca2+-ATPase activity, reduced glutathione level, and ghost protein pattern were studied. In the bottom fraction, containing most heavily damaged RBCs, calcium level ranged from 143 to 244 mumol/L RBCs (healthy G6PD- deficient controls: 17 +/- 5 mumol/L RBCs). The Ca2+-ATPase activity ranged from 0.87 to 1.84 mumol ATP consumed/g Hb/min (healthy G6PD- deficient controls: 2.27 +/- 0.4). Sodium dodecyl s
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Turrini, F., A. Naitana, L. Mannuzzu, G. Pescarmona, and P. Arese. "Increased red cell calcium, decreased calcium adenosine triphosphatase, and altered membrane proteins during fava bean hemolysis in glucose-6- phosphate dehydrogenase-deficient (Mediterranean variant) individuals." Blood 66, no. 2 (1985): 302–5. http://dx.doi.org/10.1182/blood.v66.2.302.bloodjournal662302.

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RBCs from four glucose-6-phosphate dehydrogenase (G6PD)-deficient (Mediterranean variant) subjects were studied during fava bean hemolysis. In the density-fractionated RBC calcium level, Ca2+-ATPase activity, reduced glutathione level, and ghost protein pattern were studied. In the bottom fraction, containing most heavily damaged RBCs, calcium level ranged from 143 to 244 mumol/L RBCs (healthy G6PD- deficient controls: 17 +/- 5 mumol/L RBCs). The Ca2+-ATPase activity ranged from 0.87 to 1.84 mumol ATP consumed/g Hb/min (healthy G6PD- deficient controls: 2.27 +/- 0.4). Sodium dodecyl sulfate- p
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Cardon, Tristan, Isabelle Fournier, and Michel Salzet. "SARS-Cov-2 Interactome with Human Ghost Proteome: A Neglected World Encompassing a Wealth of Biological Data." Microorganisms 8, no. 12 (2020): 2036. http://dx.doi.org/10.3390/microorganisms8122036.

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Conventionally, eukaryotic mRNAs were thought to be monocistronic, leading to the translation of a single protein. However, large-scale proteomics have led to a massive identification of proteins translated from mRNAs of alternative ORF (AltORFs), in addition to the predicted proteins issued from the reference ORF or from ncRNAs. These alternative proteins (AltProts) are not represented in the conventional protein databases and this “ghost proteome” was not considered until recently. Some of these proteins are functional and there is growing evidence that they are involved in central functions
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Dissertations / Theses on the topic "Ghost proteins"

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Garcia, del Rio Diego Fernando. "Studying protein complexes for assessing the function of ghost proteins (Ghost in the Cell)." Electronic Thesis or Diss., Université de Lille (2022-....), 2023. https://pepite-depot.univ-lille.fr/ToutIDP/EDBSL/2023/2023ULILS115.pdf.

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Le cancer de l'ovaire (OvCa) est le cancer le plus mortel parmi les cancers féminins. Il est souvent diagnostiqué tardivement ou mal diagnostiqué, ce qui le rend difficile à traiter. Les options de traitement incluent la chirurgie ou la chimiothérapie, toutefois la résistance à la chimiothérapie est un problème majeur. Il est donc urgent de trouver de nouvelles cibles et de développer de nouvelles stratégies pour surmonter cette résistance.Dans ce contexte le protéome fantôme est une source potentiellement riche de biomarqueurs. Le protéome fantôme, ou protéome alternatif, est composé de proté
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Lee, Sang 1972. "Molecular analysis of the DlgPSD-95 family of membrane-associated guanylate kinases in the weakly electric fish, Apteronotus leptorhynchus." Thesis, McGill University, 1999. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=29906.

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Members of the Dlg/PSD-95 protein family have a modular organization with multiple protein interaction domains and are thought to be important in the organization of synapses. A degenerate primer PCR strategy was used to screen for members of this family in the central nervous system of Apteronotus leptorhynchus, which possesses an electrosensory system that is well-suited for the study of synaptic organization and the subcellular localization of proteins. A. leptorhynchus was found to express at least four Dlg/PSD-95 family genes as in mammals, and the full coding sequences of the homologues
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Ghosh, Subhajit [Verfasser], and Markus [Akademischer Betreuer] Hecker. "Role of the focal adhesion protein zyxin in hypertension-induced cardiovascular remodelling / Subhajit Ghosh ; Betreuer: Markus Hecker." Heidelberg : Universitätsbibliothek Heidelberg, 2015. http://d-nb.info/1180301854/34.

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Ghosh, Sanchita [Verfasser], Andreas Gutachter] Müller, and Triantafyllos [Gutachter] [Chavakis. "The regulation of endoplasmic reticulum stress by activated protein C in diabetic nephropathy / Sanchita Ghosh ; Gutachter: Andreas Müller, Triantafyllos Chavakis." Magdeburg : Universitätsbibliothek Otto-von-Guericke-Universität, 2019. http://d-nb.info/1219966347/34.

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Ghosh, Sanchita [Verfasser], Andreas [Gutachter] Müller, and Triantafyllos [Gutachter] Chavakis. "The regulation of endoplasmic reticulum stress by activated protein C in diabetic nephropathy / Sanchita Ghosh ; Gutachter: Andreas Müller, Triantafyllos Chavakis." Magdeburg : Universitätsbibliothek Otto-von-Guericke-Universität, 2019. http://d-nb.info/1219966347/34.

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Ghosh, Madhumita [Verfasser]. "Structural and biochemical characterization of proteins involved in cancer / Madhumita Ghosh." 2005. http://d-nb.info/974284823/34.

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Books on the topic "Ghost proteins"

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Graber, Jennifer. 1893 to 1903. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190279615.003.0008.

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With allotment legislation passed, American Protestants vigorously campaigned for the dissolution of reservations and tribal governments. They also amplified their efforts to “civilize” Native people. They sent numerous missionaries to Indian Country. They argued for increased funding for Indian education, especially off-reservation boarding schools that separated Native children from their families. Kiowas struggled to hold on to their lands and maintain communal ties in an increasingly difficult environment. No longer practicing one of their central communal rites, Kiowas turned to other sou
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Comics, Gwandanaland. Complete Ghost Rider : Volume 1 : Gwandanaland Comics #114 -- the Original Golden Age Ghost Rider! He Protects the West from Outlaws, Living and Unliving! This Book: From Issues #1-14. Independently Published, 2019.

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Book chapters on the topic "Ghost proteins"

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Bojesen, Inge N., and Eigil Bojesen. "Fatty acid-binding to erythrocyte ghost membranes and transmembrane movement." In Cellular Fatty Acid-binding Proteins. Springer US, 1990. http://dx.doi.org/10.1007/978-1-4615-3936-0_26.

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Boulanger, Pascale. "Purification of Bacteriophages and SDS-PAGE Analysis of Phage Structural Proteins from Ghost Particles." In Methods in Molecular Biology. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60327-565-1_13.

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Delvecchio, Vito G., Tim Alefantis, Rodolfo A. Ugalde, et al. "Identification of Protein Candidates for Developing Bacterial Ghost Vaccines againstBrucella." In Methods of Biochemical Analysis. John Wiley & Sons, Inc., 2005. http://dx.doi.org/10.1002/0471973165.ch19.

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Mordden, Ethan. "Dancing With a Ghost." In Pick a Pocket Or Two. Oxford University Press, 2021. http://dx.doi.org/10.1093/oso/9780190877958.003.0006.

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This chapter evaluates British musicals in the 1930s and 1940s. This period, the chapter argues, was characterized by a lack of ambition. One problem was the paucity of Jewish writers in the UK. This ethnic group is notable for imaginative expertise in musical theatre and this is one of many reasons why the American brand is so protean. The most disappointing element could be argued to be passéiste choreography. In the meantime, the American musical was letting dance evolve most originally than in the UK. It is worth noting that Charles B. Cochran hired American choreographers for his most asp
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Uchihara, Toshiki. "Intrinsic Templates for Neurodegenerations Featuring Disease-Specific Axonal or Dendritic Vulnerability." In The Evolutionary Roots of Human Brain Diseases, edited by Nico J. Diederich, Martin Brüne, Katrin Amunts, and Christopher G. Goetz. Oxford University PressNew York, 2024. http://dx.doi.org/10.1093/med/9780197676592.003.0005.

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Abstract Human brain enlargement is associated with an increase of dendritic spines as well as axonal elongation and branching. These evolutionarily driven adaptations are hotspots for initiation of neurodegeneration in Parkinson’s disease (PD), Alzheimer’s disease (AD), and amyotrophic lateral sclerosis (ALS). They predict selective vulnerability for various protein deposits and propagation routes and are coined here disease-specific “intrinsic templates.” For instance, a human nigrostriatal axon is highly branched to yield 1,000,000 axon terminals. In PD, this highly branched non-myelinated
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Ng, Jenna. "Holograms/Holographic Projections : Ghosts Amongst the Living; Ghosts of the Living." In The Post-Screen Through Virtual Reality, Holograms and Light Projections. Amsterdam University Press, 2021. http://dx.doi.org/10.5117/9789463723541_ch04.

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This chapter explicates holographic projections as the second instantiation of post-screen media. Often mistaken as holograms, these projections of images ranging from Tupac to Julian Assange to holographic protests redraw the boundaries between life and death, and enable a re-imagination of ghosts, deadness, aliveness and afterlife. The chapter argues for four different moments in a history of ghosts in the media: resurrection; necrophilia; necromancy; and interactivity. The last facilitates spectral life in the post-screen through considering holographic projections of both dead and living f
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Koch, Christof. "Diffusion, Buffering, and Binding." In Biophysics of Computation. Oxford University Press, 1998. http://dx.doi.org/10.1093/oso/9780195104912.003.0017.

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In Chap. 9 we introduced calcium ions and alluded to their crucial role in regulating the day-to-day life of neurons. The dynamics of the free intracellular calcium is controlled by a number of physical and chemical processes, foremost among them diffusion and binding to a host of different proteins, which serve as calcium buffers and as calcium sensors or triggers. Whereas buffers simply bind Ca2+ above some critical concentration, releasing it back into the cytoplasm when [Ca2+]i has been reduced below this level, certain proteins— such as calmodulin—change their conformation when they bind
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Haughton, Hugh. "Tradition and Phantasmagoria." In The Oxford Handbook of W.B. Yeats. Oxford University Press, 2023. http://dx.doi.org/10.1093/oxfordhb/9780198834670.013.18.

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Abstract In his essay on ‘Dante’, T. S. Eliot claimed magisterially that ‘Dante and Shakespeare divide the modern world between them. There is no third.’ On this reading, if we discount the classical poets, Dante and Shakespeare are the most charged avatars of poetic tradition. This was equally true for W. B. Yeats, a poet with a comparable sense of spiritual belatedness and whose Irish background put him at a fraught angle to European tradition. Though Yeats generally undervalues Shakespearean comedy, the plausibility of the ‘gay’ knowledge he ascribes to Hamlet and Lear partly depends on Sha
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Gallo, Giuseppe. "Reducing Compounds Roles in Oxidative Stress Relieving of Human Red Blood Cells." In Reactive Oxygen Species [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.99977.

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Oxidative stress is the consequence of an imbalance between pro-oxidant and antioxidant processes. Antioxidants that counteract reactive oxygen species do not all work the same way. Both resveratrol and the more powerful 4-hydroxytyrosol are excellent reducing agents. Polyphenol treatment (red wine polyphenols, resveratrol and catechin) is associated with a significant increase in anion permeability for chloride compared with control and 2.2′-azobis-2 amidinopropan dihydrochloride affected cells. Treatment with polyphenols was associated with a significant reduction in mean ± standard error of
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Spoo, Robert. "Introduction." In James Joyce and the Language of History. Oxford University PressNew York, NY, 1994. http://dx.doi.org/10.1093/oso/9780195087499.003.0001.

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Abstract The word “history” reverberates throughout Ulysses like the laugh ofa ghost. Fiercely contested and continually appropriated, it can probably lay claim to more transformations than the protean dog Stephen Dedalus watches on Sandymount Strand. The Englishman Haines observes with imperial serenity that “it seems history is to blame” for his nation’s treatment of Ireland (1.649), while Stephen complains that “history ... is a nightmare from which I am trying to awake” (2.377). Mr. Deasy, the prating, imperturbable Orangeman, affirms that history moves “towards one great goal, the manifes
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Conference papers on the topic "Ghost proteins"

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FACON, T., J. GOUPEMAND, C. CARON, M. ZANDECKI, M. H. ESTIENNE, and A. COSSON. "GRAY PLATELET SYNDROME AND IDIOPATHIC PULMONARY FIBROSIS OCCURRING IN THE SAME PATIENT : A FORTUITOUS ASSOCIATION?" In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644559.

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A 46 yr old Caucasian woman has been diagnosed as having a congenital deficiency of platelet a-granules (gray platelet syndrome - GPS) associated with an extensive idiopathic pulmonary fibrosis (IPF). The patient had a life long history of bleeding tendency including dental bleedings in childhood, intraperitoneal bleeding, metrorrhagias which led to hysterectomy, and post-operative hemorrhages. When aged 16, splenectomy was performed because of a mild thrombocytopenia but did not result in a subsequent improvement of the platelet count. The spleen was enlarged and showed an excess of fibrous t
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