Academic literature on the topic 'Goniothalamin'

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Journal articles on the topic "Goniothalamin"

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Goh, SH, GCL Ee, CH Chuah, and C. Wei. "Styrylpyrone Derivatives From Goniothalamus dolichocarpus." Australian Journal of Chemistry 48, no. 2 (1995): 199. http://dx.doi.org/10.1071/ch9950199.

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Styrylpyrone derivatives (+)-goniothalamin (1), (+)-goniothalamin epoxide (2) and (–)-iso-5-deoxygoniopypyrone (4b), and the acetogenin (+)-annonacin (7) were bioactive compounds isolated from the stem bark of Goniothalamus dolichocarpus. The stereochemical relationships for (+)-goniothalamin epoxide (2), (+)-isogoniothalamin epoxide (3) and (+)-goniodiol diacetate (6) were established by chemical transformations and single-crystal X-ray crystallography.
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Takemura, Tomoko, Tsunashi Kamo, Raihan Ismil, et al. "Plant Growth Inhibitor from the Malaysian Medicinal Plant Goniothalamus andersonii and Related Species." Natural Product Communications 7, no. 9 (2012): 1934578X1200700. http://dx.doi.org/10.1177/1934578x1200700924.

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A crude methanol extract of Goniothalamus andersonii J. Sinclair strongly inhibited elongation of lettuce ( Lactuca sativa L.) radicles. We conducted bioassay-guided purification of G. andersonii bark extract and obtained goniothalamin as the major bioactive compound. Its EC50 values against elongation of lettuce radicles and hypocotyls were 50 and 125 μmol L−1, respectively. Among the six species tested, timothy was the most sensitive to goniothalamin. Quantification of this compound in other Goniothalamus species suggested that the plant inhibitory activity of this genus is explainable by go
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Wasano, Naoya, Tomoko Takemura, Raihan Ismil, Baki Bakar, and Yoshiharu Fujii. "Transcriptomic Evaluation of Plant Growth Inhibitory Activity of Goniothalamin from the Malaysian Medicinal Plant Goniothalamus andersonii." Natural Product Communications 10, no. 5 (2015): 1934578X1501000. http://dx.doi.org/10.1177/1934578x1501000507.

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Goniothalamin produced by the Malaysian medicinal plant, Goniothalamus andersonii J. Sinclair, strongly inhibits plant growth. However, its mode of action has not been characterized at the gene expression level. We conducted DNA microarray assay to analyze the changes in early gene responses of Arabidopsis thaliana seedlings. After a 6-h exposure to goniothalamin, we observed an upregulation of genes highly associated with heat response, and 22 heat shock protein ( AtHSP) genes were upregulated more than 50 fold. Together with these genes, we observed upregulation of the genes related to oxida
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Ahmad, Fasihuddin Badruddin, Wan Ahmad Tukol, Siraj Omar, and Atan Mohd Sharif. "5-Acetyl goniothalamin, a styryl dihydropyrone from Goniothalamus uvaroides." Phytochemistry 30, no. 7 (1991): 2430–31. http://dx.doi.org/10.1016/0031-9422(91)83674-a.

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Sangrueng, Kallaya, Saksri Sanyacharernkul, Sirinapa Nantapap, Narong Nantasaen, and Wilart Pompimon. "Bioactive Goniothalamin from Goniothalamus tapis with Cytotoxic Potential." American Journal of Applied Sciences 12, no. 9 (2015): 650–53. http://dx.doi.org/10.3844/ajassp.2015.650.653.

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Semprebon, SC, Â. de Fátima, SR Lepri, D. Sartori, LR Ribeiro, and MS Mantovani. "(S)-Goniothalamin induces DNA damage, apoptosis, and decrease in BIRC5 messenger RNA levels in NCI-H460 cells." Human & Experimental Toxicology 33, no. 1 (2013): 3–13. http://dx.doi.org/10.1177/0960327113491506.

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(R)-Goniothalamin (R-GNT) is a secondary metabolite isolated from the plants of the genus Goniothalamus. This molecule has attracted the attention of researchers because of its selective cytotoxicity against tumor cells and its ability to induce apoptosis. (S)-Goniothalamin (S-GNT) is a synthetic enantiomer of R-GNT, and its mechanism of action is largely unknown. In this study, we investigated the activity of S-GNT in a human non-small cell lung cancer NCI-H460 cells. We observed that the cells exposed to this compound exhibited cytotoxicity in a concentration-dependent manner. Based on the d
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Harsh, Philip, and George A. O'Doherty. "De novo asymmetric syntheses of (+)-goniothalamin, (+)-goniothalamin oxide, and 7,8-bis-epi-goniothalamin using asymmetric allylations." Tetrahedron 65, no. 26 (2009): 5051–55. http://dx.doi.org/10.1016/j.tet.2009.03.097.

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Peng, Xiaoshui, Anpai Li, Hao Shen, Tongxing Wu, and Xinfu Pan. "Facile Enantioselective Synthesis of 6R-(+)-Goniothalamin and (6R, 7R, 8R)-(+)-Goniothalamin Oxide." Journal of Chemical Research 2002, no. 7 (2002): 330–32. http://dx.doi.org/10.3184/030823402103172176.

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Facile enantioselective total syntheses of 6R-(+)-goniothalamin 1 and (6R, 7R, 8R)-(+)-goniothalamin oxide 2 were achieved through the Sharpless kinetic resolution of racemic secondary 2- furylmethanol 3 in a short synthetic route.
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Rasol, Nurulfazlina Edayah, Fasihuddin Badruddin Ahmad, Chun-Wai Mai, et al. "Styryl Lactones from Roots and Barks Goniothalamus lanceolatus." Natural Product Communications 13, no. 12 (2018): 1934578X1801301. http://dx.doi.org/10.1177/1934578x1801301203.

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A new styryl lactone, 5 R,6 R-5-hydroxy-6-styryltetrahydropyrane-2-one 2 was isolated from the roots of an endemic Goniothalamus lanceolatus Miq. of Sarawak, Malaysia. Furthermore, seven previously undescribed diastereomers, 5 R,6 R-5-hydroxygoniothalamin 3, 5 R,6 R-5-acetylgoniothalamin 4, 6 S,7 S,8 S-goniodiol-7-monoacetate 5, 6 S,7 S,8 S-goniodiol-8-monoacetate 6, goniofupyrone B 7, deoxygoniopypyrone B 8 and 1 S,5 S,7 R,8 S,3- endo,7- endo-(+)-8- epi-9-deoxygoniopypyrone acetate 9, along with six known styryl lactones (1, 10–15) were also isolated and characterized. 6 S-goniothalamin 1 is
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Peng, Xiaoshui, Anpai Li, Hao Shen, Tongxing Wu, and Xinfu Pan. "Facile Enantioselective Synthesis of 6R-(+)-Goniothalamin and (6R,7R,8R)-(+)-Goniothalamin Oxide." ChemInform 34, no. 1 (2003): no. http://dx.doi.org/10.1002/chin.200301216.

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Dissertations / Theses on the topic "Goniothalamin"

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Raihan, binti Ismil. "Evaluation of Malaysian plants for allelopathic potentials, and application of allelopathic Goniothalamus andersonii J. Sinclair as a natural herbicide." Kyoto University, 2019. http://hdl.handle.net/2433/242708.

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Kyoto University (京都大学)<br>0048<br>新制・課程博士<br>博士(農学)<br>甲第21831号<br>農博第2344号<br>新制||農||1068(附属図書館)<br>学位論文||H31||N5203(農学部図書室)<br>京都大学大学院農学研究科地域環境科学専攻<br>(主査)教授 平井 伸博, 准教授 赤松 美紀, 教授 縄田 栄治<br>学位規則第4条第1項該当
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Barcelos, Rosimeire Coura 1981. "Síntese e avaliação da atividade antiproliferativa de análogos da goniotalamina, aza-goniotalamina e piplartina." [s.n.], 2013. http://repositorio.unicamp.br/jspui/handle/REPOSIP/249268.

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Orientador: Ronaldo Aloise Pilli<br>Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Química<br>Made available in DSpace on 2018-08-23T10:20:29Z (GMT). No. of bitstreams: 1 Barcelos_RosimeireCoura_D.pdf: 15482677 bytes, checksum: f8abc41bb1731100795495890fe0c509 (MD5) Previous issue date: 2013<br>Resumo: Esse trabalho descreve a preparação de 48 compostos inéditos inspirados nas estruturas da goniotalamina (23) e da piplartina (210), bem como a avaliação da citotoxicidade in vitro desses derivados frente a uma variedade de linhagens de células tumorais humanas. Foram sintet
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Pereira, Vanessa Caixeta. "Síntese e avaliação biológica de derivados de goniotalamina." [s.n.], 2011. http://repositorio.unicamp.br/jspui/handle/REPOSIP/249241.

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Orientador: Ronaldo Aloise Pilli<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Química<br>Made available in DSpace on 2018-08-19T04:40:46Z (GMT). No. of bitstreams: 1 Pereira_VanessaCaixeta_M.pdf: 3243379 bytes, checksum: e0935d08b333881437e8413863fa0ff7 (MD5) Previous issue date: 2011<br>Resumo: A goniotalamina (9), produto natural isolado de diversas plantas do gênero Goniothalamus, vem se destacando por sua potência em teste de triagem in vitro contra linhagens de células tumorais, bem como pelos resultados positivos em modelos tumorais in vivo. Isso faz com
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Vendramini-Costa, Débora Barbosa 1984. "Goniotalamina : atividade antitumoral e anti-inflamatória." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/317629.

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Orientadores: João Ernesto de Carvalho, Ronaldo Aloise Pilli<br>Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-09-28T18:41:42Z (GMT). No. of bitstreams: 1 Costa_DeboraBarbosaVendramini_D.pdf: 5920460 bytes, checksum: d6638ad4d3d0a96e4bbcdb55823f3254 (MD5) Previous issue date: 2012<br>Resumo: A carcinogênese é um processo longo, multi-etapas, onde células normais progressivamente adquirem um fenótipo neoplásico. Sua origem é favorecida por fatores genéticos, exposição à carcinógenos químicos, infecções crônicas e incorporação de
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Marquissolo, Cilene. "Sintese e atividade biologica de analogos furanicos da goniotalamina." [s.n.], 2009. http://repositorio.unicamp.br/jspui/handle/REPOSIP/249248.

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Orientador: Ronaldo Aloise Pilli<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Quimica<br>Made available in DSpace on 2018-08-14T13:10:56Z (GMT). No. of bitstreams: 1 Marquissolo_Cilene_M.pdf: 4919703 bytes, checksum: f834b50c778a98043d8f699e6b2947b9 (MD5) Previous issue date: 2009<br>Resumo: Este trabalho tem como objetivo preparar análogos furânicos da goniotalamina 31, 32 e 33 em suas duas formas enantioméricas, utilizando-se a alilação catalítica e assimétrica nas condições de Keck e a reação de metátese de olefinas para fechamento de anel. Estes análogos fo
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Pelizzaro-Rocha, Karin Juliane 1985. "Modulação da agressividade do câncer de pâncreas, estudo in vitro." [s.n.], 2013. http://repositorio.unicamp.br/jspui/handle/REPOSIP/314041.

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Orientadores: Carmen Veríssima Ferreira Halder, Ronaldo Aloise Pilli<br>Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-08-23T09:59:14Z (GMT). No. of bitstreams: 1 Pelizzaro-Rocha_KarinJuliane_D.pdf: 18909118 bytes, checksum: fa9cec97e3d81e8fb670dab95bc1bc4d (MD5) Previous issue date: 2013<br>Resumo: O resumo poderá ser visualizado no texto completo da tese digital quando liberada<br>Abstract: The abstract is available with the full electronic document when available<br>Doutorado<br>Bioquimica<br>Doutora em Biologia Funcional e
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Dumitrescu, Lidia. "Synthèse et activité antitumorale d'analogues fluorés de produits naturels issus de Goniothalamus : Nouveaux aspects de synthèse dans les alcools fluorés." Paris 11, 2009. http://www.theses.fr/2009PA114818.

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Cette thèse repose essentiellement sur la synthèse, l’évaluation biologique, et l’étude de la stabilité métabolique d’analogues fluorés de quatre produits naturels issus de Goniothalamus (goniothalamine, goniodiol, goniotriol, et howiinol A) possédant une activité cytotoxique intéressante. Tout d’abord, afin de mieux comprendre les effets du fluor sur les propriétés physiques, physico-chimiques et biologiques de molécules à visée thérapeutique, une étude statistique a été réalisée à partir d’une base de données de produits bioactifs répertoriés dans la littérature de 1990 à 2008. Nous avons en
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Gillard, Frédéric. "Chirons pour la synthèse de la (+)-anamarine synthèse de la (+)-goniothalamine /." Grenoble 2 : ANRT, 1988. http://catalogue.bnf.fr/ark:/12148/cb37613909w.

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Gillard, Frédéric. "Chirons pour la synthese de la (+)-anamarine : synthese de la (+)-goniothalamine." Université Louis Pasteur (Strasbourg) (1971-2008), 1988. http://www.theses.fr/1988STR13076.

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La (+) anamarine comporte une partie cyclique : une dihydro-5,6 pyrannone-2 et une partie acyclique dont la stereochimie est celle du d-gulose. La partie acyclique est preparee a partir de la d-gulonolactone. La partie cyclique est synthetisee a partir du d-glucose. La synthese de la (+)goniothalamine est effectuee
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Barbion, Julien. "Asymmetric synthesis of (+)-altholactone, a styryllactone from various goniothalamus species." [S.l.] : [s.n.], 2006. http://deposit.ddb.de/cgi-bin/dokserv?idn=982464541.

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Book chapters on the topic "Goniothalamin"

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Vino, P., C. Santhosh, A. Maruthupandian, et al. "Chemopreventive Effects of Natural Bioactive Compounds From the Genus Goniothalamus: A Review and Perspectives." In The Phytochemical and Pharmacological Aspects of Ethnomedicinal Plants. Apple Academic Press, 2021. http://dx.doi.org/10.1201/9781003100768-8.

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Conference papers on the topic "Goniothalamin"

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Azizan, Izzatul Hidayah, Rozida Mohd Khalid, Laily Din, and Jalifah Latip. "Isolation and biotransformation of goniothalamin in the production of goniothalamin analogue." In THE 2016 UKM FST POSTGRADUATE COLLOQUIUM: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2016 Postgraduate Colloquium. Author(s), 2016. http://dx.doi.org/10.1063/1.4966748.

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Barcelos, Rosimeire C., and Ronaldo A. Pilli. "Synthesis of Novel Goniothalamin Analogs." In 14th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0327-1.

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de Toledo, Ian, Ronaldo Aloise Pilli, and Ismael Raitz. "Synthesis of a goniothalamin triazolic analogue." In XXV Congresso de Iniciação Cientifica da Unicamp. Galoa, 2017. http://dx.doi.org/10.19146/pibic-2017-78682.

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Caixeta, V., D. B. Vendramini-Costa, R. A. Pilli, and J. E. de Carvalho. "Synthesis of Lactam Derivatives of Goniothalamin." In 14th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0374-1.

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Pastre, Julio Cezar, and Ronaldo Aloise Pilli. "Synthesis of 3,4-Dihydro- -Pyrone Analogues of Goniothalamin." In 14th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0278-1.

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Pastre, Julio C., Philip R. D. Murray, Duncan L. Browne, Ronaldo A. Pilli, and Steven V. Ley. "Integrated Batch and Continuous Flow Process for the Synthesis of Goniothalamin." In 15th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_2013914162426.

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Bruder, Marjorie, and Ronaldo Aloise Pilli. "A tandem ring-closing/cross-coupling metathesis reaction toward the short synthesis of goniothalamin analogs." In 14th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0372-1.

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Vendramini Costa, Débora Barbosa, Ralph A. Francescone, Oxana Dmitrieva, et al. "Abstract 2799: Goniothalamin, a natural product, modulates the inflammatory microenvironment on colitis and colitis-associated cancer." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-2799.

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Punganuru, Surendra R., Hanumantha Rao Madala, Debasish Basak, and Kalkunte S. Srivenugopal. "Abstract 3694: Selective killing of cancer cells by the styryl lactone (R)- goniothalamin is mediated through glutathione conjugation, oxidative stress and a marked reactivation of the R175H mutant p53 protein." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-3694.

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Wijaya, Viriyanata, Supriyatna Supriyatna, and Tiana Milanda. "ISOLASI SENYAWA AKTIF DARI FRAKSI ETIL ASETAT DAUN Goniothalamus Macrophyllus." In Mulawarman Pharmaceuticals Conferences. Fakultas Farmasi, Universitas Mulawarman, Samarinda, 2015. http://dx.doi.org/10.25026/mpc.v2i1.49.

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