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Dissertations / Theses on the topic 'Goniothalamin'

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Published: 4 June 2021
Last updated: 6 February 2022

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1

Raihan, binti Ismil. "Evaluation of Malaysian plants for allelopathic potentials, and application of allelopathic Goniothalamus andersonii J. Sinclair as a natural herbicide." Kyoto University, 2019. http://hdl.handle.net/2433/242708.

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Kyoto University (京都大学)<br>0048<br>新制・課程博士<br>博士(農学)<br>甲第21831号<br>農博第2344号<br>新制||農||1068(附属図書館)<br>学位論文||H31||N5203(農学部図書室)<br>京都大学大学院農学研究科地域環境科学専攻<br>(主査)教授 平井 伸博, 准教授 赤松 美紀, 教授 縄田 栄治<br>学位規則第4条第1項該当
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2

Barcelos, Rosimeire Coura 1981. "Síntese e avaliação da atividade antiproliferativa de análogos da goniotalamina, aza-goniotalamina e piplartina." [s.n.], 2013. http://repositorio.unicamp.br/jspui/handle/REPOSIP/249268.

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Orientador: Ronaldo Aloise Pilli<br>Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Química<br>Made available in DSpace on 2018-08-23T10:20:29Z (GMT). No. of bitstreams: 1 Barcelos_RosimeireCoura_D.pdf: 15482677 bytes, checksum: f8abc41bb1731100795495890fe0c509 (MD5) Previous issue date: 2013<br>Resumo: Esse trabalho descreve a preparação de 48 compostos inéditos inspirados nas estruturas da goniotalamina (23) e da piplartina (210), bem como a avaliação da citotoxicidade in vitro desses derivados frente a uma variedade de linhagens de células tumorais humanas. Foram sintet
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3

Pereira, Vanessa Caixeta. "Síntese e avaliação biológica de derivados de goniotalamina." [s.n.], 2011. http://repositorio.unicamp.br/jspui/handle/REPOSIP/249241.

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Orientador: Ronaldo Aloise Pilli<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Química<br>Made available in DSpace on 2018-08-19T04:40:46Z (GMT). No. of bitstreams: 1 Pereira_VanessaCaixeta_M.pdf: 3243379 bytes, checksum: e0935d08b333881437e8413863fa0ff7 (MD5) Previous issue date: 2011<br>Resumo: A goniotalamina (9), produto natural isolado de diversas plantas do gênero Goniothalamus, vem se destacando por sua potência em teste de triagem in vitro contra linhagens de células tumorais, bem como pelos resultados positivos em modelos tumorais in vivo. Isso faz com
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4

Vendramini-Costa, Débora Barbosa 1984. "Goniotalamina : atividade antitumoral e anti-inflamatória." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/317629.

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Orientadores: João Ernesto de Carvalho, Ronaldo Aloise Pilli<br>Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-09-28T18:41:42Z (GMT). No. of bitstreams: 1 Costa_DeboraBarbosaVendramini_D.pdf: 5920460 bytes, checksum: d6638ad4d3d0a96e4bbcdb55823f3254 (MD5) Previous issue date: 2012<br>Resumo: A carcinogênese é um processo longo, multi-etapas, onde células normais progressivamente adquirem um fenótipo neoplásico. Sua origem é favorecida por fatores genéticos, exposição à carcinógenos químicos, infecções crônicas e incorporação de
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5

Marquissolo, Cilene. "Sintese e atividade biologica de analogos furanicos da goniotalamina." [s.n.], 2009. http://repositorio.unicamp.br/jspui/handle/REPOSIP/249248.

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Orientador: Ronaldo Aloise Pilli<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Quimica<br>Made available in DSpace on 2018-08-14T13:10:56Z (GMT). No. of bitstreams: 1 Marquissolo_Cilene_M.pdf: 4919703 bytes, checksum: f834b50c778a98043d8f699e6b2947b9 (MD5) Previous issue date: 2009<br>Resumo: Este trabalho tem como objetivo preparar análogos furânicos da goniotalamina 31, 32 e 33 em suas duas formas enantioméricas, utilizando-se a alilação catalítica e assimétrica nas condições de Keck e a reação de metátese de olefinas para fechamento de anel. Estes análogos fo
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6

Pelizzaro-Rocha, Karin Juliane 1985. "Modulação da agressividade do câncer de pâncreas, estudo in vitro." [s.n.], 2013. http://repositorio.unicamp.br/jspui/handle/REPOSIP/314041.

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Orientadores: Carmen Veríssima Ferreira Halder, Ronaldo Aloise Pilli<br>Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-08-23T09:59:14Z (GMT). No. of bitstreams: 1 Pelizzaro-Rocha_KarinJuliane_D.pdf: 18909118 bytes, checksum: fa9cec97e3d81e8fb670dab95bc1bc4d (MD5) Previous issue date: 2013<br>Resumo: O resumo poderá ser visualizado no texto completo da tese digital quando liberada<br>Abstract: The abstract is available with the full electronic document when available<br>Doutorado<br>Bioquimica<br>Doutora em Biologia Funcional e
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7

Dumitrescu, Lidia. "Synthèse et activité antitumorale d'analogues fluorés de produits naturels issus de Goniothalamus : Nouveaux aspects de synthèse dans les alcools fluorés." Paris 11, 2009. http://www.theses.fr/2009PA114818.

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Cette thèse repose essentiellement sur la synthèse, l’évaluation biologique, et l’étude de la stabilité métabolique d’analogues fluorés de quatre produits naturels issus de Goniothalamus (goniothalamine, goniodiol, goniotriol, et howiinol A) possédant une activité cytotoxique intéressante. Tout d’abord, afin de mieux comprendre les effets du fluor sur les propriétés physiques, physico-chimiques et biologiques de molécules à visée thérapeutique, une étude statistique a été réalisée à partir d’une base de données de produits bioactifs répertoriés dans la littérature de 1990 à 2008. Nous avons en
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8

Gillard, Frédéric. "Chirons pour la synthèse de la (+)-anamarine synthèse de la (+)-goniothalamine /." Grenoble 2 : ANRT, 1988. http://catalogue.bnf.fr/ark:/12148/cb37613909w.

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9

Gillard, Frédéric. "Chirons pour la synthese de la (+)-anamarine : synthese de la (+)-goniothalamine." Université Louis Pasteur (Strasbourg) (1971-2008), 1988. http://www.theses.fr/1988STR13076.

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La (+) anamarine comporte une partie cyclique : une dihydro-5,6 pyrannone-2 et une partie acyclique dont la stereochimie est celle du d-gulose. La partie acyclique est preparee a partir de la d-gulonolactone. La partie cyclique est synthetisee a partir du d-glucose. La synthese de la (+)goniothalamine est effectuee
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10

Barbion, Julien. "Asymmetric synthesis of (+)-altholactone, a styryllactone from various goniothalamus species." [S.l.] : [s.n.], 2006. http://deposit.ddb.de/cgi-bin/dokserv?idn=982464541.

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11

Seidel, Véronique. "Contribution a l'etude des annonaceae : i. etude chimique des ecorces de cleistopholis glauca, des feuilles de cleistopholis patens et piptostigma fasciculata, des parties aeriennes de goniothalamus thwaitesii et goniothalamus gardneri. ii. etude pharmacologique de cleistopholis glauca et cleistopholis patens (doctorat : pharmacognosie)." Lille 2, 1999. http://www.theses.fr/1999LIL2P254.

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12

Tang, Chin-cheung, and 鄧展翔. "Systematics and phylogenetics of goniothalamus (annonaceae) : a study of putative rapid, recent evolutionary radiation in a species-rich palaeotropical genus." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/202378.

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Goniothalamus is one of the largest genera in the pantropical angiosperm family Annonaceae. It includes c. 130 species of trees, distributed in tropical lowland and submontane forests in tropical Asia, Australia and Melanesia. Previous studies have indicated that Goniothalamus shows a significantly higher diversification rate in comparison to closely related taxa and that its species diversity is the result of a relatively recent radiation. The phylogenetic framework necessary for testing this hypothesis, including the investigation of potential intrinsic and environmental correlates of this p
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13

LI, MING-XIN, and 李明鑫. "Isolation and synthesis of goniothalamin and its analogues." Thesis, 1991. http://ndltd.ncl.edu.tw/handle/67798650082903705396.

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14

Huang, Yu-ting, and 黃鈺婷. "Goniothalamin Induceed DNA Damage and Apoptosis inHepatocellular Carcinoma Derived Cells." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/92849446417424997160.

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碩士<br>國立中山大學<br>生物醫學研究所<br>98<br>The goniothalamin (GTN) and related styryl-lactones were found to be cytotoxic and apoptotic to a variety of tumor cell lines including breast cancer MCF-7, cervical cancer HeLa and leukemia HL60. In HL60 cells, GTN triggers mitochondria dysfunction, caspase activation and eventually, apoptosis. In this study, we demonstrated that GTN was able to induce apoptosis in hepatocellular carcinoma derived cells, SK-Hep1 and Hep-3B cells via upregulation of the phorbol-12-myristate-13-induced 1 (PMAIP1) protein , alternation of mitochondrial membrane potentials (P &amp
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15

Tsai, Cheng-Hui, and 蔡振輝. "Goniothalamin induces TP53-dependent and -independent apoptosis in hepatocellular carcinoma derived cells." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/3xk5fh.

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碩士<br>國立中山大學<br>生物醫學研究所<br>96<br>The objective was to study apoptotic effects and underlying molecular mechanisms of goniothalamin (GTN) in hepatocellular carcinoma (HCC)-derived cells. The GTN that isolated from Goniothalamus amuyon, was found to possess profound cytotoxic activities against human SK-Hep1 and Hep-3B cells in vitro. The cytotoxicity of GTN/cell viability was measured by MTT assay at 570-nm absorbance and the IC50 at 72 h were determined as 7.5, 17 mM in SK-Hep1 and Hep-3B respectively. The GTN induced cell death and accumulation of reactive oxygen species in HCC-derived cells.
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16

Chen, Wen-Ying, and 陳文穎. "Studies on the apoptotic effects and mechanisms of action of goniothalamin and tubocapsenolide A in human breast cancer MDA-MB-231 cells." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/41140119324965851076.

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博士<br>高雄醫學大學<br>天然藥物研究所<br>96<br>Apoptosis is presently one of the most obvious targets for cancer treatment as its relatively common inactivation in tumors, contributes to carcinogenesis, as well as resistance to chemotherapy. In the present study, the anticancer mechanisms of goniothalamin and tubocapsenolide A were investigated at molecular levels in human breast cancer MDA-MB-231 cells, respectively. Goniothalamin is a styryl-lactone with putative anticancer activities, but its mechanism of action has never been explored before. Goniothalamin treatment of cells significantly induced cell
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17

Tsai, Tsung-Yi, and 蔡宗益. "Asymmetric Synthesis of Goniotriol in Goniothalamus Sesquipedalis." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/03109042298723838882.

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碩士<br>中國文化大學<br>應用化學研究所<br>92<br>Abstract Goniotriol is one of styrylpyrone compound which isolated from Goniothalamus Sesquipedalis and showed inhibitiory activity on several human tumor cells. In this thesis, total synthesis of goniotriol was by Sharpless asymmetric method was investigated. Ethyl 3-benzoylacrylate was chosen as the starting material. Treatment of this keto ester with ethylene glycol in benzene provided ketal GT-1 in good yield. The ketal reacted with AD-mix-β by Sharpless asymmetric dihydroxylation to give optically active diol GT-2. The hydroxy grou
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18

Li, Wen-Hsiung, and 李文雄. "Synthetic Study of Antitumor Goniotriol in Goniothalamus sesquipedalis." Thesis, 2002. http://ndltd.ncl.edu.tw/handle/32765281392066734446.

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碩士<br>中國文化大學<br>應用化學研究所<br>90<br>Abstract Goniotriol was a styryl lactone isolated from the leaves and twigs of Goniothalamus sesquipedalis and was shown to be cytotoxic to several human tumor cells, which prompted us to study its synthesis. We started the synthesis with methyl mandelate.After protection of the hydroxyl group with methoxymethyl ether, the ester was reduced by DIBAL to give the unstable aldehyde, which was immediately treated with methyl (triphenylphosphoranylidene) acetate to give the Wittig product.However, it was unsuccessful to transform the
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19

Yu, Jin-Hsien, and 余俊賢. "Chemical Constituents and Cytotoxicity of the Leaves of Goniothalamus amuyon." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/58096890058677558088.

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碩士<br>高雄醫學大學<br>天然藥物研究所<br>89<br>Abstract Twenty compounds including eleven styrylpyrones (6R,7R,8R)-goniodiol (1), (6R,7S,8S)-goniodiol (2), (6R,7R,8R)-goniodiol-7-mono-acetate (3),(6R,7R,8R)-goniodiol-8-monoacetate (4), (6R,7S,8S)-8-meth-oxygoniodiol (5), (5S,6R,7R,8R)-goniotriol (6), (5S,6R,7S,8S)-goniotriol (7), (5S, 6R, 7R, 8R)-7-methoxygoniotriol (8), goniothalamin (9), goniothalamin epoxide (10), and (+)-5-deoxy-goniopypyrone (11), four alkaloids, piperlactam C (12), aristolactam FII (13), liriodenine (14), and lysicamine (15), one lignan, (+)-pinoresinol (16), two aromatic c
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20

Barbion, Julien [Verfasser]. "Asymmetric synthesis of (+)-altholactone, a styryllactone from various goniothalamus species / vorgelegt von Julien Barbion." 2006. http://d-nb.info/982464541/34.

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21

Lan, Yu-Hsuan, and 藍于琁. "Studies on the Chemical Constituents and Biological Activities of the Goniothalamus and Fissistigma species." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/46341776017212508536.

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