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Dissertations / Theses on the topic 'GPAI'

Author: Grafiati
Published: 4 September 2021
Last updated: 29 July 2025

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1

BIRONNEAU, LAURENT. "Le choix des methodes et outils de pilotage de la production en milieu industriel. Elements d'analyse et proposition d'un referentiel d'aide au choix." Rennes 1, 1999. http://www.theses.fr/1999REN10203.

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Le but de cette recherche etait essentiellement de determiner les facteurs qui influent sur le choix d'une methode et d'un outil de pilotage de la production, et de proposer, en coherence avec cette etude, un referentiel synthetique montrant les liens privilegies entre les differentes situations industrielles et l'utilisation de telle ou telle approche de pilotage. Ce double objectif devait permettre d'apporter une contribution a la connaissance du pilotage de la production tant d'un point de vue theorique, en precisant notamment l'adequation des methodes et outils de pilotage aux differentes
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2

Patel, Akruti. "NOVEL REGULATORS OF GPVI-MEDIATED PLATELET ACTIVATION." Diss., Temple University Libraries, 2017. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/473397.

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Biomedical Sciences<br>Ph.D.<br>Platelets are anucleate cells that are crucial mediators of hemostasis and thrombosis. Under physiological conditions, platelets are maintained in a quiescent state within the vasculature. Upon vascular injury, an essential receptor that initiates platelet activation upon interaction with sub-endothelial collagen is Glycoprotein VI (GPVI). The activation of platelets leads to platelet shape change, granular secretion, thromboxane A2 (TXA2) synthesis, and integrin IIb3-mediated platelet aggregation and thrombus formation. In the past, a lot of effort has been p
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3

Jiang, Peng. "GPVI plaquettaire : cible thérapeutique et ciblage du collagène." Paris 7, 2014. http://www.theses.fr/2014PA077054.

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La Glycoprotéine VI (GPVI) plaquettaire a un rôle critique dans la thrombose et donc un intérêt potentiel en thérapie antithrombotique. En outre, GPVI ayant une haute affinité pour le collagène, des molécules mimes semblent prometteuses comme traceurs moléculaires du collagène et le diagnostic de la fibrose. Le losartan, un antagoniste du récepteur de type I à l'angiotensine II, a été proposé comme étant un agent bloquant GPVI mais aussi le récepteur du thromboxane A2. Nous avons réévalué l'effet du losartan sur les plaquettes et établi in vitro que le losartan inhibe à forte dose l'activation
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4

Thomé, Franck. "Un système pour l'audit et l'aide à la conception des organisations de gestion de la production." Chambéry, 1989. http://www.theses.fr/1989CHAMS001.

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L'outil présenté utilise les principes de la méthode GRAI en particulier une modélisation hiérarchique et fonctionnelle du système étudié. Il s'agit d'un système expert capable d'élaborer un bilan d'analyse à partir d'une représentation du système de gestion de la production étudié, qui est entrée à la fois graphiquement et sous la forme d'objets stockés dans une base de données.
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5

Weil, Georges Emile Demongeot Jacques. "L'hôpital au service du malade transfert des concepts, des méthodes, des outils de la gestion de la production /." S.l. : Université Grenoble 1, 2008. http://tel.archives-ouvertes.fr/tel-00337856.

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6

Thomas, Dafydd Huw. "Regulation of Syk activity in GPVI-mediated platelet activation." Diss., Temple University Libraries, 2010. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/92028.

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Pharmacology<br>Ph.D.<br>Activation of platelets is essential for hemostasis. Following damage to the vascular endothelium collagen is exposed, to which platelets stably adhere. After adhesion on collagen, a signaling cascade is initiated, mediated by Glycoprotein VI (GPVI), which results in platelet activation. A major signaling protein in GPVI signaling is Spleen tyrosine kinase (Syk). It undergoes phosphorylation and activation following GPVI stimulation. Syk's central role in this physiological process suggests regulation of its activity is required to maintain the platelets response to co
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7

Noirot, Sylvie. "Contribution à une méthode d'acquisition des applications informatiques de gestion de production." Bordeaux 1, 1998. http://www.theses.fr/1998BOR10672.

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La necessite d'amelioration de competitivite oblige les industriels a utiliser des solutions informatiques de type produit (progiciels de gestion de production par exemple). Le choix des produits du marche est de plus en plus difficile (criteres economiques, criteres techniques et criteres fonctionnels). Ce travail de recherche propose des concepts (bases sur les objectifs a atteindre et utilisant les principes des activites grai) coherents avec la methodologie grai, permettant d'une part de specifier une application informatique de gestion de production et d'autre part d'etablir les bases d'u
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8

Sof, Said. "Etude des profils de température dans les plaquettes de silicium multicristallin en cours d’élaboration et simulation d'un système de pilotage du faisceau électronique d'irradiation destiné a diminuer les contraintes d'origine thermique." Lyon, INSA, 1992. http://www.theses.fr/1992ISAL0053.

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La technique EPR (Electron Powder Ribbon) permet l'élaboration des rubans de silicium multi cristallin destinés à la fabrication des cellules solaires en utilisant une ligne de fusion obtenue par déflexion magnétique d'un faisceau électronique. Les forts gradients de température sont la cause principale de l'apparition des contraintes thermiques. Leur élimination nécessite une meilleure connaissance des profils de température. A cette fin, nous avons procédé à une modélisation en 3 dimensions des échanges thermiques ; après localisation et évaluation des contraintes à partir des profils de tem
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9

Mourani, Iyad Xie Xiaolan. "Etude des systèmes de productions automatisée soumis à des aléas." [S.l.] : [s.n.], 2006. ftp://ftp.scd.univ-metz.fr/pub/Theses/2006/Mourani.Iyad.SMZ0627.pdf.

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10

Simpson, Clare. "GPI-anchored proteins as potential plasmodesmal components." Thesis, University of East Anglia, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.502203.

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Plasmodesmata (Pds) traverse the cell wall to establish a symplastic continuum through most of the plant. Despite central roles in plant growth development and defence very little is know about their constituent parts or mechanisms of regulation. Rapid and reversible deposition of callose in the cell wall surrounding the Pd apertures is proposed to provide a regulatory process through physical constriction of the symplastic channel. From a proteomic analysis of Arabidopsis thaliana suspension cell walls, we identified a family of Pd callose-binding proteins (PDCBs) which target Pds in newly-di
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11

Carnall, N. "The expression of Trypanosoma brucei GPI-PLC." Thesis, University of Cambridge, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.597297.

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<I>Trypanosoma brucei</I>, the causal agents of African sleeping sickness contains a membrane bound glycosylphosphatidylinositol-specific phospholipase C (GPI-PLC) which exhibits exquisite specificity for GPI anchors. The enzyme is of interest as its action has the effect of releasing the variant specific surface glycoprotein (VSG) monolayer from the cell membrane <I>in vitro</I>, an event that is possibly analogous to a life cycle stage dependent process occurring <I>in vivo</I>. The regulation of expression of the GPI-PLC gene operates mainly at the post-transcription level and has been inve
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12

Smith, Karen Louise. "Structure and function of neuronal GPI domains." Thesis, King's College London (University of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.313392.

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13

Savage, Sydney, Hannah Oliver, Rylee Burchfield, Bethany Pickard, and Sarah Pack. "Student's Proximity to Campus Affects their GPA." Digital Commons @ East Tennessee State University, 2020. https://dc.etsu.edu/secfr-conf/2020/schedule/33.

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The purpose of this study was to determine the correlation between a students Grade Point Average (GPA) and a student's proximity to campus. There were also two other independent variables studied, the students gender and the number of roommates the student has. The results showed that there is no correlation between GPA and proximity to campus or GPA and number of roommates. The only correlation found, which was slight, was between GPA and gender.
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14

Douglas, Joanne Tracy. "The expression of recombinant varicella-zoster virus glycoproteins gpII and gpIII." Thesis, University of Southampton, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.296112.

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15

Gavin, Rebecca Louise. "The tetraspanin Tspan18 regulates GPVI induced platelet activation and Ca²⁺ mobilisation." Thesis, University of Birmingham, 2015. http://etheses.bham.ac.uk//id/eprint/5903/.

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Platelet activation and subsequent thrombus formation are important for preventing excessive blood loss at sites of vascular injury, a process termed haemostasis. However, excessive platelet activation at sites of atherosclerotic plaque rupture can lead to thrombus formation, which may occlude the vessel and cause heart attack or stroke. The platelet collagen receptor GPVI is essential for thrombus formation, but is largely dispensable for haemostasis. Tetraspanins are transmembrane proteins which compartmentalise the membrane through formation of dynamic tetraspanin-enriched microdomains. Due
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16

LAGRUE, LAK HAL ANNE-HELENE. "Caracterisation et expression megacaryocytaire de la gpvi, recepteur plaquettaire du collagene." Paris 7, 2001. http://www.theses.fr/2001PA077038.

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Les interactions plaquettes-collagene jouent un role primordial dans la formation des thromboses au site de lesion vasculaire. Plusieurs recepteurs du collagene sont presents a la surface plaquettaire : gpiaiia, gpiv, gpvi, p65 et tiiicbp. Nos travaux ont contribue a caracteriser un de ces recepteurs, la gpvi. Nous avons identifie un ligand specifique de la gpvi, la convulxine, et ainsi nous avons pu montrer que lors de l'activation des plaquettes par le collagene, la gpvi est responsable de la mobilisation du calcium intracellulaire, de l'agregation et de la secretion. Nous avons constate que
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17

Guimaraes, Renato. "Contribution à la réactivité des industries manufacturières : conception d'une interface logicielle liant la planification au pilotage d'atelier." Vandoeuvre-les-Nancy, INPL, 1997. http://www.theses.fr/1997INPL098N.

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18

Huppertz, Jérôme. "Modulation inflammatorischer Prozesse mittels GPI-verankerter Chemokin-Analoga." Diss., lmu, 2009. http://nbn-resolving.de/urn:nbn:de:bvb:19-109640.

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19

Böcker, Sophia. "GPI-verankerte Chemokine als Adjuvantien in der Tumortherapie." Diss., Ludwig-Maximilians-Universität München, 2013. http://nbn-resolving.de/urn:nbn:de:bvb:19-158566.

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20

Mojica, Muñoz Ann-Katrin [Verfasser], and Wolfgang [Akademischer Betreuer] Siess. "Effect of GPVI-Fc in combination with standard antiplatelet drugs and of GPVI-Fc fused to CD39 on platelet thrombus formation / Ann-Katrin Mojica Muñoz ; Betreuer: Wolfgang Siess." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2019. http://d-nb.info/1196009104/34.

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21

Ellison, Stuart Michael. "CD148 : a positive regulator of GPVI and αIIbβ3 proximal signalling in platelets". Thesis, University of Birmingham, 2010. http://etheses.bham.ac.uk//id/eprint/727/.

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Platelets are small anucleate blood cells that plug holes in damage blood vessels. They do so by adhering to exposed extracellular matrix proteins at sites of injury and aggregating together. Platelet responsiveness to injury is controlled by a diverse repertoire of surface receptors that can be divided into two broad categories based on how they signal; the tyrosine kinased-linked receptors and the G protein-coupled receptors (GPCRs). There has been much work on elucidating the functions of tyrosine kinases in platelets, whereas protein tyrosine phosphatases (PTPs) have been under-investigate
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22

Fourniol, Sylvie. "Automatisation d'un calcul des charges d'une fonderie d'aluminium." Lyon 1, 1989. http://www.theses.fr/1989LYO10190.

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23

Spinosa, Luiz Marcio. "Contribution à la modélisation d'entreprises manufacturières distribuées fondée sur une approche multi-agents." Aix-Marseille 3, 1996. http://www.theses.fr/1996AIX30070.

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Les travaux de recherche developpes dans cette these s'inscrivent dans un contexte d'activites relevant a la fois de l'intelligence artificielle et de la productique, que d'aucuns appellent productique distribuee et intelligente. Ils contribuent a l'emergence de nouveaux concepts, tant sur le plan definitoire que sur le plan operatoire, permettant de mieux apprehender la modelisation des systemes de production et, par consequence, de mieux maitriser la productique distribuee et intelligente. Nous avons introduit un nouveau concept: emd (entreprise manufacturiere distribuee). L'emd definie, a p
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24

Ayadi, Karim. "Propositions méthodologiques pour la conception de systèmes d'aide à la conduite en production." Aix-Marseille 3, 1998. http://www.theses.fr/1998AIX30061.

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De nos jours, la reactivite d'une entreprise depend de l'amelioration des differents modes de conduite de son systeme de production et plus particulierement de la prise en charge des perturbations. Il s'agit de proposer aux acteurs de la production un systeme de conduite capable de leur fournir une aide au cours des processus de decision qu'ils developpent. Ces processus donnent lieu a des actes pour permettre d'apporter une reponse rapide aux perturbations qu'ils rencontrent. Dans cette optique, une approche sociotechnique des systemes de production a ete retenue (notions d'acteur, de decisio
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25

Martin, Pascal. "L'entité d'usinage au service de l'ingénierie concourante : application à la gamme automatique dans l'ameublement." Nancy 1, 1997. http://www.theses.fr/1997NAN10312.

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Les premiers outils de conception ou de fabrication et autres techniques assistées par ordinateur ont permis de répondre à un certain nombre de besoins en matière de modélisation et simulation numérique de produit, automatisation de tâches en production, représentation et visualisation des résultats. Immédiatement est apparue la nécessité de faire communiquer ces tâches afin de limiter le nombre d'opérations manuelles de reprise des données. Pour cela, des interfaces spécialisées furent développées : cette démarche baptisée intégration par les interfaces se traduit par le couplage entre deux o
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26

Dettmann, Ralf Peter. "VSG-GPI-Ankerfragmente aus Trypanosoma brucei eine neuartige Synthesestrategie /." [S.l. : s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=964186071.

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27

Lapa, Constantin. "GPI-verankertes mucin CXCL10 als potentielles Adjuvans moderner Tumortherapie." Diss., lmu, 2011. http://nbn-resolving.de/urn:nbn:de:bvb:19-129097.

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28

Raymond, Frank Damian. "Inositol specific phospholipase D activity : a GPI-cleaving enzyme." Thesis, University College London (University of London), 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321569.

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29

Posner, Stephen. "Estimating the Genuine Progress Indicator (GPI) for Baltimore, MD." ScholarWorks @ UVM, 2010. http://scholarworks.uvm.edu/graddis/183.

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In order to better manage progress toward improved human welfare, governments and organizations around the world have begun to report on more comprehensive indicators of environmental, social, and economic conditions. The Genuine Progress Indicator (GPI) has proven useful as a measure of economic welfare by incorporating changes in environmental conditions, resource stocks, social capital, income distribution, and other non-marketed economic activity. Studies at the local scale have also found the GPI to be an effective tool for informing debate and stimulating questions about the natur
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30

Rusin, Demetrit Scott. "Sports Participation and GPA for African-American Male Students." ScholarWorks, 2015. https://scholarworks.waldenu.edu/dissertations/1211.

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Abstract Improving the academic success and graduation rates of African-American males has been a major focus of both scholars and practitioners in the United States. Locally, African-American males at an urban Title 1 school were experiencing the lowest grade point averages, American College Test scores, and graduation rates in the district. In response to these academic declines, this study focused on the tenets of Bechtol's sports participation theory, which holds that students who play sports experience greater academic achievement and adult success in life. The purpose of this study was t
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31

Vigneron, Nicolas. "Caractérisation des bases moléculaires de l'évolution de la symbiose mycorhizienne à arbuscules chez les plantes." Thesis, Toulouse 3, 2019. http://www.theses.fr/2019TOU30260.

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La symbiose mycorhizienne à arbuscules (AM) est une association entre la plupart des embryophytes et des champignons ubiquitaires du sol qui appartiennent à la famille des Glomeromycotina. La symbiose mycorhizienne a été proposé comme l'une des innovations clés qui ont permis la colonisation de la terre par des plantes il y a 450 millions d'années. Les champignons mycorhiziens colonisent leur hôte de façon interne et produisent des structures intracellulaires, appelées arbuscules, où ils fournissent de l'eau et des nutriments minéraux à leur hôte en échange de carbone sous forme de sucres et d
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32

Alshehri, Osama Mohammed D. "The role of GPVI and CLEC-2 in platelet activation by miscellaneous ligands." Thesis, University of Birmingham, 2016. http://etheses.bham.ac.uk//id/eprint/6880/.

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Platelets are an essential factor in wound repair and blood clotting, where exposed sub-endothelial extracellular matrix (ECM) proteins induce activation during vascular injury. However, platelets can also be activated by a diverse range of stimuli that share little-to-no resemblance in structure to each other, or to recognized ligands of platelet receptors. These stimuli include diesel exhaust particles (DEP), various peptides including 4N1-1 and Champs, lipoproteins such as PAM3-CSK4, and large polysaccharides for example, fucoidan, and dextran. In this thesis, I demonstrate that this seemin
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33

Fernandes, Fabrício Freitas. "Caracterização funcional dos genes PGA13 e PGA58 de Candida albicans." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/17/17136/tde-17122008-132351/.

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A incidência de infecções por fungos oportunistas na população de pacientes imunocomprometidos tem aumentado nos últimos anos, e estas são, principalmente, causadas por Candida albicans. Este patógeno oportunista pode crescer em diferentes formas, variando de levedura, pseudohifa e hifa e essa transição morfológica está associada com a virulência. Na transição de levedura para hifa, genes hifa-específicos são expressos e muitos deles codificam proteínas que possuem uma molécula de GPI (glicosilfosfatilinositol), mas a maioria (66%) das proteínas preditas ancoradas por GPI (PGAs), ainda possuem
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34

Branham, Keith. "THE EFFECTS OF AN ACADEMIC SUPPORT SERVICES UNIT ON THE GRADE POINT AVERAGE FOR STUDENTS ADMITTED ON PROBATION." Doctoral diss., University of Central Florida, 2005. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/2236.

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The goal of this research was to examine the effects, if any, the programs available from an Academic Support Services unit of a small, private, liberal arts college might have on the grade point averages of students admitted on probation over two major semesters. The assumption was that the students who utilized the services of the Academic Center for Excellence would demonstrate more increases in GPA than students who did not utilize the services. The literature review of this study found that, although there were many factors and student characteristics that could predict and explain studen
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35

Perry, Steven F. "Comparison of college GPA to the CDMSES and the OMEIS /." Available to subscribers only, 2005. http://proquest.umi.com/pqdweb?did=1172081141&sid=5&Fmt=2&clientId=1509&RQT=309&VName=PQD.

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Thesis (M.S. in Ed.)--Southern Illinois University Carbondale, 2005.<br>"Department of Educational Psychology and Special Eduation." Includes bibliographical references (leaves 57-62 ). Also available online.
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36

Borner, Georg Heinz Helmut. "The role and targeting of GPI-anchored proteins in Arabidopsis." Thesis, University of Cambridge, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.615666.

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37

Baeschlin, Daniel Kaspar. "Butanediacetals in oligosaccharide synthesis : total synthesis of a GPI anchor." Thesis, University of Cambridge, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.621500.

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38

Gittins, Robert John. "The antigenicity of varicella-zoster virus gpII studied using recombinant forms of this glycoprotein." Thesis, University of Southampton, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.316050.

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39

Hughes, Craig Edward. "Comparison of CLEC-2 and GPVI signaling in platelets : the role of adaptor proteins." Thesis, University of Birmingham, 2010. http://etheses.bham.ac.uk//id/eprint/1204/.

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GPVI activates platelets through an ITAM pathway by activation of Src and Syk kinases leading to activation of PLC\(_y\)2. CLEC-2 has been shown to activate platelets using an ITAM-like sequence in its cytoplasmic tail that is also dependent on Src and Syk kinases, but shows a partial rather than an absolute dependence on adapter SLP-76 for activation of PLC\(_y\)2. The aim of this thesis is to understand some of the key differences in these signalling pathways. GPVI is in complex with FcRwhich contains the ITAM sequence (Yxx(L/I)x\(_{6-12}\)Yxx(L/I)). These two tyrosines provide a docking s
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40

Kytková, Petra. "Konkurenceschopnost cestovního ruchu v rámci EU." Master's thesis, Vysoká škola ekonomická v Praze, 2012. http://www.nusl.cz/ntk/nusl-197281.

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The key objective of the diploma thesis is to evaluate tourism competitiveness in the European Union -- particularly which competitiveness rankings are related to tourism sector and what position the EU and its member states represent within them. Also, there is politics of the EU analysed, key documents are mentioned and future opportunities for tourism development are outlined in the diploma thesis. In conclusion, particular project is analysed. The project is an example of above mentioned competitiveness support in tourism sector of the EU.
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41

Flores, Borja Fabian. "Characterisation of the mouse glycosylphosphatidyl inositol phospholipase D (GPI-PLD) gene." Thesis, University College London (University of London), 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.404723.

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42

Di, Ying Ivy. "Regulation of PrP biology by small RNA and the GPI anchor." Thesis, University of Cambridge, 2014. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708072.

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43

Erbe, Ashlynn. "Success Off The Field: Academic Strategies of High-GPA College Athletes." BYU ScholarsArchive, 2020. https://scholarsarchive.byu.edu/etd/8507.

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This study investigated the strategies academically successful college student athletes use to do well in their class work, where academic success was defined as a 3.5 GPA for 12 or more credits for the two semesters preceding the study. Data were transcriptions of individual interviews with five male and five female athletes in seven sports at an NCAA Division I university in the western United States. Independent coders analyzed the data and agreed upon themes related to challenges to academic success and strategies to meet those challenges. Findings add to the literature by detailing self
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44

Bélanger, Marc. "Gènes impliqués dans le "shedding" des protéines GPI chez Saccharomyces cerevisiae." Master's thesis, Université Laval, 2016. http://hdl.handle.net/20.500.11794/27486.

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Les organismes eucaryotes possèdent plusieurs mécanismes de contrôle qualité en vue d'assurer leur survie en condition de stress. La réponse aux protéines mal repliées (UPR) est un mécanisme à la base de différents volets ayant pour but de ramener l'organisme vers l'homéostasie. L'étude qui suit vise à caractériser plus en profondeur un volet de cette réponse qui est lié non pas à la présence de protéines mal repliées, mais plutôt à des défauts dans l'homéostasie des lipides de la cellule. Notre étude a mis en évidence qu'une forme précise de la protéine à ancrage GPI modèle Yps1p est relâchée
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45

Huang, Jui-Han. "Functional analysis of GPI-anchored and truncated forms of HLA-A2.1." Case Western Reserve University School of Graduate Studies / OhioLINK, 1994. http://rave.ohiolink.edu/etdc/view?acc_num=case1057945291.

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46

Focareto, Nicole. "Private vs. Non-Private: A Correlational Study Between ACT and GPA." Marietta College / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=marietta1147440821.

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47

Imjeti, Naga Sailaja. "Role of cholesterol and N-glycosylation in apical sorting of GPI- APs in polarized epithelial FRT cells." Phd thesis, Université Paris Sud - Paris XI, 2011. http://tel.archives-ouvertes.fr/tel-00682284.

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Epithelial cells represent the ability to polarize with an apical and basolateral domains which differ markedly in proteins, lipid composition and therefore in function. This asymmetry reflects the ability of epithelial cells to sort newly synthesized proteins and lipid to either cell surface. While the signals responsible for basolateral targeting of the proteins have been clearly understood, the situation regarding the apical sorting of proteins is more obscure. We have previously shown that differently from basolateral GPI-APs oligomerization in the Golgi apparatus is necessary for apical s
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48

Hatfield, Meghan. "PROSTASIN IS EXPRESSED IN BENIGN PROSTATIC HYPERPLASIA AND REGULATES CELL PROLIFERATION AND INVASION VIA INOS, ICAM-1, AND CYCLI." Master's thesis, University of Central Florida, 2008. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/4260.

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ABSTRACT Prostasin is expressed in normal prostate epithelial cells but down-regulated in prostate cancers, while prostasin re-expression in invasive prostate cancer cells reduced invasion. We examined prostasin expression and function in benign prostatic hyperplasia (BPH). We evaluated prostasin expression in 12 BPH specimens by immunohistochemistry, and evaluated the impact of prostasin silencing by siRNA on the expression of the inducible nitric oxide synthase (iNOS), intercellular adhesion molecule-1 (ICAM-1), and cyclin D1, as well as on cell proliferation and invasion, using the BPH-1 hu
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49

Patel, Monika A. "Role of Arabidopsis thaliana WRKY45 in Response to Green Peach Aphid Infestation, Drought, and Salinity Stresses." Thesis, University of North Texas, 2020. https://digital.library.unt.edu/ark:/67531/metadc1703299/.

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This study shows that Arabidopsis thaliana WRKY45 gene has an important role in limiting green peach aphid (GPA; Myzus persicae Sülzer) infestation. WRKY45 belongs to the WRKY family of transcription factors, which is one of the largest transcription factor family in plants. In response to GPA infestation, expression of WRKY45 was systemically upregulated in leaves and roots, with highest expression in the vascular tissues, which are the site of aphid feeding. GPA colonization was better on the wrky45 mutant compared to the wild-type (WT) plant. In contrast, GPA poorly colonized plants that we
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50

Martinez, Fernandez Irene. "La ruta FUL-AP2 y la longevidad de los meristemos en Arabidopsis thaliana. Bases moleculares y potencial biotecnológico." Doctoral thesis, Universitat Politècnica de València, 2017. http://hdl.handle.net/10251/88394.

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The development of all organs of the plant depends on the activity of the meristems and adjacent areas. Monocarpic plants show only one reproductive cycle before they senescence and die. The senescence and death of these plants is preceded by a global proliferative arrest of meristems (GPA). That way, the number of fruits/flowers that they produce during their lives depends on the proliferative activity of apical meristems of the branches and on the time GPA occurs. The study of the mechanisms that control GPA, as well as a better knowledge of genes involved in the maintenance of merismatic ce
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