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Relevant bibliographies by topics / GPI 1046

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Academic literature on the topic 'GPI 1046'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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Journal articles on the topic "GPI 1046"

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Steiner, Joseph P., Kathryn B. Payne, Christopher Drummond Main, et al. "GPI-1046 Increases Presenilin-1 Expression and Restores NMDA Channel Activity." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 37, no. 4 (2010): 457–67. http://dx.doi.org/10.1017/s0317167100010465.

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Background:Previously we showed that 6-hydroxydopamine lesions of the substantia nigra eliminate corticostriatal LTP and that the neuroimmunolophilin ligand (NIL), GPI-1046, restores LTP.Methods:We used cDNA microarrays to determine what mRNAs may be over- or under-expressed in response to lesioning and/or GPI-1046 treatment. Patch clamp recordings were performed to investigate changes in NMDA channel function before and after treatments.Results:We found that 51 gene products were differentially expressed. Among these we found that GPI-1046 treatment up-regulated presenilin-1 (PS-1) mRNA abund

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Steiner, Joseph P., David Galey, Norman J. Haughey, Daniella Asch, and Avindra Nath. "Neuroprotective and Antiretroviral Effects of the Immunophilin ligand GPI 1046." Journal of Neuroimmune Pharmacology 2, no. 1 (2007): 49–57. http://dx.doi.org/10.1007/s11481-006-9060-0.

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Wu, Y. R., R. Levy, P. Ashby, R. R. Tasker, and J. O. Dostrovsky. "Does stimulation of the GPi control dyskinesia by activating inhibitory axons?" Movement Disorders 16, no. 2 (2001): 208–16. http://dx.doi.org/10.1002/mds.1046.

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Li, Feng, Takeshi Hayashi, Nobuhiko Omori, et al. "Protection against ischemic brain damage in rats by immunophilin ligand GPI-1046." Journal of Cerebral Blood Flow & Metabolism 25, no. 1_suppl (2005): S16. http://dx.doi.org/10.1038/sj.jcbfm.9591524.0016.

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Emborg, M. E., P. Shin, B. Roitberg, et al. "Systemic Administration of the Immunophilin Ligand GPI 1046 in MPTP-Treated Monkeys." Experimental Neurology 168, no. 1 (2001): 171–82. http://dx.doi.org/10.1006/exnr.2000.7592.

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Li, Feng, Nobuhiko Omori, Takeshi Hayashi, et al. "Protection against ischemic brain damage in rats by immunophilin ligand GPI-1046." Journal of Neuroscience Research 76, no. 3 (2004): 383–89. http://dx.doi.org/10.1002/jnr.20067.

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Moss, Sheldon J., Brenda Birkestrand, and Stephen C. Fowler. "The neuroimmunophilin GPI-1046 partially protects against 3-acetylpyridine toxicity in the rat." Neuroscience Letters 321, no. 1-2 (2002): 53–56. http://dx.doi.org/10.1016/s0304-3940(01)02571-x.

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Eberling, J. "The Immunophilin Ligand GPI-1046 Does Not Have Neuroregenerative Effects in MPTP-Treated Monkeys." Experimental Neurology 178, no. 2 (2002): 236–42. http://dx.doi.org/10.1006/exnr.2002.8023.

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Burnett, Arthur L., Melissa F. Kramer, Susan Dalrymple, and John T. Isaacs. "Nonimmunosuppressant immunophilin ligand GPI-1046 does not promote in vitro growth of prostate cancer cells." Urology 65, no. 5 (2005): 1003–7. http://dx.doi.org/10.1016/j.urology.2004.11.033.

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Sari, Y., and S. N. Sreemantula. "Neuroimmunophilin GPI-1046 reduces ethanol consumption in part through activation of GLT1 in alcohol-preferring rats." Neuroscience 227 (December 2012): 327–35. http://dx.doi.org/10.1016/j.neuroscience.2012.10.007.

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Dissertations / Theses on the topic "GPI 1046"

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Sreemantula, Sai Nandini. "Glutamate Transporter 1 in the Central Nervous System: Potential Target for the Treatment of Alcohol Dependence." University of Toledo Health Science Campus / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=mco1333546775.

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Cecchetti, Dario. "Rilievi cinematici continui condotti con sensori a basso costo." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2016. http://amslaurea.unibo.it/10464/.

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Nel qui presente elaborato vengono descritte le principali caratteristiche del sistema di posizionamento GPS e le tecniche di rilievo. Particolare attenzione viene posta al rilievo cinematico continuo con sensori a basso costo (Ublox EVK 7P). Inotre verra descritta nel dettaglio la strumentazione atta ad acquisire il segnale, e la relativa preparazione. In particolare i dati acquisiti dalla strumentazione verranno elaborati con appositi software, dai quali si otterranno diverse soluzioni. Di seguito sara presente anche la procedura di elaborazione dei dati registrati. In fine le soluzioni otte

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Manning, Dennis, Rick Williams, and Paul Ferrill. "Data Filtering Unit (DFU): Dealing With Cryptovariable Keys in Data Recorded Using the IRIG 106 Chapter 10 Format." International Foundation for Telemetering, 2006. http://hdl.handle.net/10150/604140.

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ITC/USA 2006 Conference Proceedings / The Forty-Second Annual International Telemetering Conference and Technical Exhibition / October 23-26, 2006 / Town and Country Resort & Convention Center, San Diego, California<br>Recent advancements in IRIG 106 Chapter 10 recording systems allow the recording of all on board 1553 bus and PCM traffic to a single media. These advancements have also brought about the issue of extracting data with different levels of classification that was written to single location. Carrying GPS “smart” weapons further complicates this issue since the recording of GPS

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Needham, Timothy G. "A Low Rate Data Link For A High Performance Differential Global Positioning System." Ohio University / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1212702229.

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Book chapters on the topic "GPI 1046"

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Robertazzi, Arturo. "9. Twitter per gli editori: come, quanto, perché?" In La lettura digitale e il web. Ledizioni, 2011. http://dx.doi.org/10.4000/books.ledizioni.1042.

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Traverso, Marta. "8. Il ruolo dei social network letterari per gli editori." In La lettura digitale e il web. Ledizioni, 2011. http://dx.doi.org/10.4000/books.ledizioni.1040.

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Politarczyk, K., Ł. Stepniak, M. Kozinoga, and T. Kotwicki. "Is there any difference in pulmonary testing parameters due to spirometry reference values? A study in adolescents with idiopathic scoliosis." In Studies in Health Technology and Informatics. IOS Press, 2021. http://dx.doi.org/10.3233/shti210476.

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The Global Lung Function Initiative (GLI 2012) presented multi-ethnic spirometry reference values that are recommended to be used instead previous Zapletals’ reference values. The study aimed to compare the values of the pulmonary parameters calculated according to the Zapletals’ versus the GLI 2012 reference values in adolescents with idiopathic scoliosis. Preoperative pulmonary testing and radiographic evaluation were performed in 39 adolescents (29 females, 10 males) aged 12–17 years. The thoracic Cobb angle ranged 50°–104°. Forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) were measured. The percentages of predicted values of FVC (%FVC) and the FEV1 (%FEV1) were calculated according to the Zapletals’ reference values and to the GLI 2012 reference values. The subgroup analysis was performed for the subjects with Cobb curve 50°–74° (N=26) versus the subjects with Cobb curve 75°–104° (N=13). Mean %FVC was significantly higher using the Zapletals’ reference values 86.1%±16.4 versus 84.6%±15.6 using the GLI 2012 reference values, p=0.0116. Mean %FEV1 was significantly higher using the Zapletals’ reference values 84.5%±18.2 versus 80.0%±16.3 using GLI 2012 reference values, p=0.000001. The subgroup analysis revealed significant difference of %FVC in moderate (p=0.033974) and no difference in severe curves (p=0.1993). The %FEV1 differences were significant in both moderate (p=0.000011) and severe curves (p=0.0334). The study demonstrated that a significant difference might be observed in the spirometry parameters due to the applied reference values. These differences might be taken into account during the spirometry examination interpretation.

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Taber, Douglass F. "Organocatalyzed C–C Ring Construction: The Hayashi Synthesis of PGE1 Me Ester." In Organic Synthesis. Oxford University Press, 2015. http://dx.doi.org/10.1093/oso/9780190200794.003.0073.

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Xiaohua Liu and Xiaoming Feng of Sichuan University devised (J. Org. Chem. 2013, 78, 6322) a catalyst that mediated the addition of the ylide 2 to the enone 1 to give 3. Peng-fei Xu of Lanzhou University found (Chem. Commun. 2013, 49, 4625) that the vinyl pyrrole 4 was sufficiently nucleophilic to add to 5, leading to the cyclobutane 6. Albert Moyano of the Universitat de Barcelona added (Eur. J. Org. Chem. 2013, 3103) 8 to the unsaturated aldehyde 7 to give the β-amino acid precursor 9. Eugenia Marqués-López and Mathias Christmann, now at Freie Universität Berlin effected (Synthesis 2013, 45, 1016) the intramolecular Michael cyclization of 10 to give 11. Delong Liu and Wanbin Zhang of Shanghai Jiao Tong University showed (Synthesis 2013, 45, 1612) that 12 and 13 could be combined to give the cyclopentane 14. Ismail Ibrahem and Armando Córdova of Mid Sweden University combined (Angew. Chem. Int. Ed. 2013, 52, 6050) 15 and 16 to give 17, with good control of the quaternary center. Kamal Nain Singh of Panjab University prepared (Synthesis 2013, 45, 1406) a proline-derived sulfoxide that mediated the addition of cyclohexanone 18 to 19. Intramolecular aldehyde alkylation is underdeveloped as a synthetic method. David W.C. MacMillan of Princeton University established (J. Am. Chem. Soc. 2013, 135, 9358) a single-electron transfer variant, cyclizing 21 to 22. Arianna Quintavalla of the University of Bologna effected (Adv. Synth. Catal. 2013, 355, 938) the double addition of nitromethane 24 to 23 to give 25. John Cong-Gui Zhao of the University of Texas at San Antonio reported (Chem. Eur. J. 2013, 19, 1666; J. Org. Chem. 2013, 78, 4153) parallel results (not pictured) with aryl enones as the acceptors. Bor-Cherng Hong of the National Chung Cheng University condensed (Eur. J. Org. Chem. 2013, 2472) 26 with the alcohol 27 to give 28. Again, good control of the quaternary center was observed. Marc C. Kimber of Loughborough University used (J. Org. Chem. 2013, 78, 3476) an organocatalyst to rearrange the prochiral endoperoxide 29 to the hydroxy enone, to which malonate 30 was added to give 31.

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Marks II, Robert J. "Signal Recovery." In Handbook of Fourier Analysis & Its Applications. Oxford University Press, 2009. http://dx.doi.org/10.1093/oso/9780195335927.003.0015.

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The literature on the recovery of signals and images is vast (e.g., [23, 110, 112, 257, 391, 439, 791, 795, 933, 934, 937, 945, 956, 1104, 1324, 1494, 1495, 1551]). In this Chapter, the specific problem of recovering lost signal intervals from the remaining known portion of the signal is considered. Signal recovery is also a topic of Chapter 11 on POCS. To this point, sampling has been discrete. Bandlimited signals, we will show, can also be recovered from continuous samples. Our definition of continuous sampling is best presented by illustration.Asignal, f (t), is shown in Figure 10.1a, along with some possible continuous samples. Regaining f (t) from knowledge of ge(t) = f (t)Π(t/T) in Figure 10.1b is the extrapolation problem which has applications in a number of fields. In optics, for example, extrapolation in the frequency domain is termed super resolution [2, 40, 367, 444, 500, 523, 641, 720, 864, 1016, 1099, 1117]. Reconstructing f (t) from its tails [i.e., gi(t) = f (t){1 − Π(t/T)}] is the interval interpolation problem. Prediction, shown in Figure 10.1d, is the problem of recovering a signal with knowledge of that signal only for negative time. Lastly, illustrated in Figure 10.1e, is periodic continuous sampling. Here, the signal is known in sections periodically spaced at intervals of T. The duty cycle is α. Reconstruction of f (t) from this data includes a number of important reconstruction problems as special cases. (a) By keeping αT constant, we can approach the extrapolation problem by letting T go to ∞. (b) Redefine the origin in Figure 10.1e to be centered in a zero interval. Under the same assumption as (a), we can similarly approach the interpolation problem. (c) Redefine the origin as in (b). Then the interpolation problem can be solved by discarding data to make it periodically sampled. (d) Keep T constant and let α → 0. The result is reconstructing f (t) from discrete samples as discussed in Chapter 5. Indeed, this model has been used to derive the sampling theorem [246]. Figures 10.1b-e all illustrate continuously sampled versions of f (t).

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Taber, Douglass F. "Heteroaromatic Construction: The Wipf Synthesis of Cycloclavine." In Organic Synthesis. Oxford University Press, 2013. http://dx.doi.org/10.1093/oso/9780199965724.003.0068.

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Wesley J. Moran of the University of Huddersfield cyclized (Tetrahedron Lett. 2011, 52, 2605) a propargylated ketone 1 with Au to give the furan 2. Shengming Ma of the Shanghai Institute of Organic Chemistry found (Synlett 2011, 931) that tri(2-furyl)phosphine catalyzed the rearrangement of cyclopropene diesters, prepared by the addition of diazomalonate to alkynes, to the corresponding alkoxy furan 4. Xihe Bi and Qian Zhang of Northeast Normal University established (Chem. Commun. 2011, 47, 809) that a simple Fe catalyst effected the condensation of 5 with 6 to give the pyrrole 7. Gianfranco Favi of the Università degli Studi di Urbino showed (J. Org. Chem. 2011, 76, 2860) that the three-component coupling of 8 with an amine 9 and a ketone 10 proceeded without catalyst to deliver the pyrrole 11. Timothy J. Donohoe of the University of Oxford homologated (Org. Lett. 2011, 13, 1036) 12 by cross-metathesis with methyl vinyl ketone, to give, after oxidation and condensation with NH4OAc, the substituted pyridine 13. Dale L. Boger of Scripps/La Jolla condensed ( Org. Lett. 2011, 13, 2492) the unsubstitued 1,2,3-triazine 15 with an enamine 14 to give 16. Shunsuke Chiba of Nanyang Technological University prepared (J. Am. Chem. Soc. 2011, 133, 6411) the pyridine 19 by oxidizing the cyclopropanol 17 in the presence of the alkenyl azide 18. Limin Wang of the East China University of Science and Technology prepared (Tetrahedron Lett. 2011, 52, 509) the 2-aminopyridine 23 by the four-component coupling of the aldehyde 20 and the ketone 22 with NH4OAc and malononitrile 21. Taking advantage of the Knochel protocol for aryl Grignard formation, Christopher J. Moody of the University of Nottingham combined (Chem. Commun. 2011, 47, 788) the adduct from 24 with the ketone 25 to give the indole 26. Carsten Bolm of RWTH Aachen extended (Org. Lett. 2011, 13, 2012) the Fe catalysis reported by Zheng to the azide 27 to give 28. Sang-gi Lee of Ewha Womans University found (Org. Lett. 2011, 13, 1350) that the Blaise adduct from the addition of 29 to the nitrile could be cyclized to the indole 30.

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Conference papers on the topic "GPI 1046"

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Ryu, Shinchiku, and Shigeaki Shiotani. "Small Craft Assistant Information System Based on GPS and Google Earth in Real Time." In ASME 2013 32nd International Conference on Ocean, Offshore and Arctic Engineering. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/omae2013-10467.

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The system is aimed at establishing the information support system for small craft operators. This system can also be used for playback and simulation purpose. The combination of 3D map service of Google earth and GPS can supply real time position and 3D geographic virtual circumstance. In this study, authors make the small craft assistant information system based on Microsoft.Net technology, GPS and Google Earth.

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Stan, Cornel, and Michel Lebrun. "Concept of Interactive Development of a GDI System with High-Pressure Modulation." In SAE 2000 World Congress. SAE International, 2000. http://dx.doi.org/10.4271/2000-01-1042.

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Sevik, James, Thomas Wallner, Michael Pamminger, Riccardo Scarcelli, Dan Singleton, and Jason Sanders. "Extending Lean and EGR-Dilute Operating Limits of a Modern GDI Engine Using a Low-Energy Transient Plasma Ignition System." In ASME 2015 Internal Combustion Engine Division Fall Technical Conference. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/icef2015-1048.

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The efficiency improvement and emissions reduction potential of lean and EGR dilute operation of spark-ignition gasoline engines is well understood and documented. However, dilute operation is generally limited by deteriorating combustion stability with increasing inert gas levels. The combustion stability decreases due to reduced mixture flame speeds resulting in significantly increased combustion initiation periods and burn durations. A study was designed and executed to evaluate the potential to extend lean and EGR-dilute limits using a low-energy transient plasma ignition system. The low-e

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Grimaldi, C. N., L. Postrioti, C. Stan, and R. Tröger. "Analysis Method for the Spray Characteristics of a GDI System with High Pressure Modulation." In SAE 2000 World Congress. SAE International, 2000. http://dx.doi.org/10.4271/2000-01-1043.

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Sharpe, W. N., J. Pulskamp, B. G. Mendis, et al. "Tensile Stress-Strain Curves of Gold Film." In ASME 2006 International Mechanical Engineering Congress and Exposition. ASMEDC, 2006. http://dx.doi.org/10.1115/imece2006-13290.

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Freestanding vapor-deposited gold films 0.15 μm, 0.5 μm, and 1.0 μm thick were tested in tension with strain measured directly in the gage section by digital imaging. The average grain size of all three films was ~ 60 nm with some large grains in the 0.15 μm material. Young's modulus decreased as the thickness decreased - from 73.1 ± 6.7 GPa to 64.7 ± 9.9 GPa to 51.4 ± 10.6 GPa respectively. The yield stress decreased from 365 ± 25 MPa to 328 ± 28 MPa, but was 371 ± 36 MPa for the 0.15 μm film, which was more brittle. Microstructural studies provide no clear explanation for this behavior.

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Harmon, J. T., and G. A. Jamieson. "TWO SIZES OF THROMBIN RECEPTORS IN SOLUBILIZED HUMAN PLATELET MEMBRANES." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644468.

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Thrombin receptors of two functional sizes (106 and 30,000) have been previously identified by the technique of radiation inactivation (Harmon and Jamieson, Biochemistry 24:58, 1985). To determine whether different s-ized populations are separable biochemically, platelet membranes solubilized in Triton X-100 were applied to a Sepharose 6B column after incubation with 125I-thrombin. Apart from unbound 125I-thrombin (40,000) the elution profile showed two radioactive peaks with apparent mol. wts. of 1−2×106 and 170,000. The bound radioactivity associated with these two peaks could be competed by

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Scarcelli, Riccardo, James Sevik, Thomas Wallner, Keith Richards, Eric Pomraning, and Peter K. Senecal. "Capturing Cyclic Variability in EGR Dilute SI Combustion Using Multi-Cycle RANS." In ASME 2015 Internal Combustion Engine Division Fall Technical Conference. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/icef2015-1045.

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Dilute combustion is an effective approach to increase the thermal efficiency of spark-ignition (SI) internal combustion engines (ICEs). However, high dilution levels typically result in large cycle-to-cycle variations (CCV) and poor combustion stability, therefore limiting the efficiency improvement. In order to extend the dilution tolerance of SI engines, advanced ignition systems are the subject of extensive research. When simulating the effect of the ignition characteristics on CCV, providing a numerical result matching the measured average in-cylinder pressure trace does not deliver usefu

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Carey, Kevin, Benjamin Abruzzo, David P. Harvie, and Christopher Korpela. "Performance Comparison of Inertial Measurement Units Fused With Odometry in Extended Kalman Filter for Dead-Reckoning Navigation." In ASME 2019 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/detc2019-98184.

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Abstract This paper aims to aid robot and autonomous vehicle designers by providing a comparison between four different inertial measurement units (IMUs) which could be used to aid in vehicle navigation in a GPS-denied or inertial-only scenario. A differential-drive ground vehicle was designed to carry the multiple different IMUs, mounted coaxially, to enable direct comparison of performance in a planar environment. The experiments focused on the growth of pose error of the ground vehicle originating from the odometry senors and the IMUs. An extended Kalman Filter was developed to fuse the odo

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Ramaekers, Wilhelmus J. S., Ferry A. Tap, Thijs W. F. M. Bouten, and Lars-Uno Axelsson. "Comparison of Different CFD Models for Predicting Emissions in an OPRA DLE Combustor." In ASME Turbo Expo 2019: Turbomachinery Technical Conference and Exposition. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/gt2019-91317.

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Abstract This paper presents a numerical investigation of natural gas combustion in an OPRA OP16 tubular DLE combustor operating in premixed mode. The aim of this study is to compare different CFD models for the accurate prediction of emissions. The numerical results are validated against experimental results obtained in an atmospheric combustion test rig. A CFD workflow using AVL FIRE software has been devised enabling accurate CO and NOx emission calculations. Different turbulence models have been employed for adiabatic flow simulations at nominal load: the k-ζ-f turbulence model, PANS and L

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Key, Christopher T., and C. Scott Alexander. "Numerical and Experimental Evaluations of a Glass-Epoxy Composite Material Under High Velocity Oblique Impacts." In 2019 15th Hypervelocity Impact Symposium. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/hvis2019-072.

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Abstract Composite materials are widely used in both the defense and commercial sectors for various applications. Many of these applications present the possibility of the composite material being subjected to high-velocity impacts, where the strain rates can be on the order of 106 s-1 or more and the pressures are often in the tens of GPa. The work presented in this paper expands upon previous work for the same materials where the impacts were normal to the composite material [1] by considering the non-ideal condition of oblique impacts that are more likely to occur in regular use.

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Reports on the topic "GPI 1046"

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Van Dierendonck, A. J., Ronald R. Hatch, and Fred Gloeckler. Proposed Revisions to RTCM SC-104 Recommended Standards for Differential NAVSTAR/GPS Service for Carrier Phase Applications. Defense Technical Information Center, 1992. http://dx.doi.org/10.21236/ada255276.

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