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Journal articles on the topic 'GPI 1046'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

Steiner, Joseph P., Kathryn B. Payne, Christopher Drummond Main, et al. "GPI-1046 Increases Presenilin-1 Expression and Restores NMDA Channel Activity." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 37, no. 4 (2010): 457–67. http://dx.doi.org/10.1017/s0317167100010465.

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Background:Previously we showed that 6-hydroxydopamine lesions of the substantia nigra eliminate corticostriatal LTP and that the neuroimmunolophilin ligand (NIL), GPI-1046, restores LTP.Methods:We used cDNA microarrays to determine what mRNAs may be over- or under-expressed in response to lesioning and/or GPI-1046 treatment. Patch clamp recordings were performed to investigate changes in NMDA channel function before and after treatments.Results:We found that 51 gene products were differentially expressed. Among these we found that GPI-1046 treatment up-regulated presenilin-1 (PS-1) mRNA abund

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2

Steiner, Joseph P., David Galey, Norman J. Haughey, Daniella Asch, and Avindra Nath. "Neuroprotective and Antiretroviral Effects of the Immunophilin ligand GPI 1046." Journal of Neuroimmune Pharmacology 2, no. 1 (2007): 49–57. http://dx.doi.org/10.1007/s11481-006-9060-0.

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3

Wu, Y. R., R. Levy, P. Ashby, R. R. Tasker, and J. O. Dostrovsky. "Does stimulation of the GPi control dyskinesia by activating inhibitory axons?" Movement Disorders 16, no. 2 (2001): 208–16. http://dx.doi.org/10.1002/mds.1046.

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4

Li, Feng, Takeshi Hayashi, Nobuhiko Omori, et al. "Protection against ischemic brain damage in rats by immunophilin ligand GPI-1046." Journal of Cerebral Blood Flow & Metabolism 25, no. 1_suppl (2005): S16. http://dx.doi.org/10.1038/sj.jcbfm.9591524.0016.

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5

Emborg, M. E., P. Shin, B. Roitberg, et al. "Systemic Administration of the Immunophilin Ligand GPI 1046 in MPTP-Treated Monkeys." Experimental Neurology 168, no. 1 (2001): 171–82. http://dx.doi.org/10.1006/exnr.2000.7592.

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6

Li, Feng, Nobuhiko Omori, Takeshi Hayashi, et al. "Protection against ischemic brain damage in rats by immunophilin ligand GPI-1046." Journal of Neuroscience Research 76, no. 3 (2004): 383–89. http://dx.doi.org/10.1002/jnr.20067.

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7

Moss, Sheldon J., Brenda Birkestrand, and Stephen C. Fowler. "The neuroimmunophilin GPI-1046 partially protects against 3-acetylpyridine toxicity in the rat." Neuroscience Letters 321, no. 1-2 (2002): 53–56. http://dx.doi.org/10.1016/s0304-3940(01)02571-x.

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8

Eberling, J. "The Immunophilin Ligand GPI-1046 Does Not Have Neuroregenerative Effects in MPTP-Treated Monkeys." Experimental Neurology 178, no. 2 (2002): 236–42. http://dx.doi.org/10.1006/exnr.2002.8023.

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9

Burnett, Arthur L., Melissa F. Kramer, Susan Dalrymple, and John T. Isaacs. "Nonimmunosuppressant immunophilin ligand GPI-1046 does not promote in vitro growth of prostate cancer cells." Urology 65, no. 5 (2005): 1003–7. http://dx.doi.org/10.1016/j.urology.2004.11.033.

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10

Sari, Y., and S. N. Sreemantula. "Neuroimmunophilin GPI-1046 reduces ethanol consumption in part through activation of GLT1 in alcohol-preferring rats." Neuroscience 227 (December 2012): 327–35. http://dx.doi.org/10.1016/j.neuroscience.2012.10.007.

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11

Höke, Ahmet, Michael Morris, and Norman J. Haughey. "GPI-1046 protects dorsal root ganglia from gp120-induced axonal injury by modulating store-operated calcium entry." Journal of the Peripheral Nervous System 14, no. 1 (2009): 27–35. http://dx.doi.org/10.1111/j.1529-8027.2009.00203.x.

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12

Zhao, Liqin, Hongying Liu, Lili Wang, and Song Li. "Modeling and synthesis of non-cyclic derivatives of GPI-1046 as potential FKBP ligands with neurotrophic properties." Bioorganic & Medicinal Chemistry Letters 16, no. 16 (2006): 4385–90. http://dx.doi.org/10.1016/j.bmcl.2006.05.044.

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13

Harper, S., J. Bilsland, L. Young, et al. "Analysis of the neurotrophic effects of GPI-1046 on neuron survival and regeneration in culture and in vivo." Neuroscience 88, no. 1 (1999): 257–67. http://dx.doi.org/10.1016/s0306-4522(98)00221-8.

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14

Parker, Eric M., Angela Monopoli, Ennio Ongini, Gianluca Lozza, and Carol M. Babij. "Rapamycin, but not FK506 and GPI-1046, increases neurite outgrowth in PC12 cells by inhibiting cell cycle progression." Neuropharmacology 39, no. 10 (2000): 1913–19. http://dx.doi.org/10.1016/s0028-3908(00)00028-9.

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15

Ross, Douglas T., Hongzhi Guo, Pamela Howorth, Yi Chen, Gregory S. Hamilton, and Joseph P. Steiner. "The small molecule FKBP ligand GPI 1046 induces partial striatal re-innervation after intranigral 6-hydroxydopamine lesion in rats." Neuroscience Letters 297, no. 2 (2001): 113–16. http://dx.doi.org/10.1016/s0304-3940(00)01683-9.

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16

Sauer, Hansjörg, Jonathan M. Francis, Hong Jiang, Gregory S. Hamilton, and Joseph P. Steiner. "Systemic treatment with GPI 1046 improves spatial memory and reverses cholinergic neuron atrophy in the medial septal nucleus of aged mice." Brain Research 842, no. 1 (1999): 109–18. http://dx.doi.org/10.1016/s0006-8993(99)01851-x.

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17

Khan, Z., G. Ferrari, M. Kasper, et al. "The non-immunosuppressive immunophilin ligand GPI-1046 potently stimulates regenerating axon growth from adult mouse dorsal root ganglia cultured in Matrigel." Neuroscience 114, no. 3 (2002): 601–9. http://dx.doi.org/10.1016/s0306-4522(02)00314-7.

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18

Graziani, Francesca, Laura Aldegheri, and Georg C. Terstappen. "High Throughput Scintillation Proximity Assay for the Identification of FKBP-12 Ligands." Journal of Biomolecular Screening 4, no. 1 (1999): 3–7. http://dx.doi.org/10.1177/108705719900400102.

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A high throughput scintillation proximity assay (SPA) was developed to identify novel ligands of FKBP-12, an immunophilin with peptidyl prolyl isomerase (rotamase) activity. Recombinant histidine-tagged FKBP-12 was expressed in Escherichia coli, purified by metal ion affinity chromatography, and immobilized to SPA beads by an antibody that recognizes the histidine tag of the recombinant protein. Using 1 nM [3H] FK506, a well-known macrolid ligand of FKBP-12, specific binding was saturable and accounted for 95% of total binding. Analysis of saturation and homologous displacement isotherms indic

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19

Winter, C., J. Schenkel, E. Bürger, C. Eickmeier, M. Zimmermann, and T. Herdegen. "The immunophilin ligand FK506, but not GPI-1046, protects against neuronal death and inhibits c-Jun expression in the substantia nigra pars compacta following transection of the rat medial forebrain bundle." Neuroscience 95, no. 3 (1999): 753–62. http://dx.doi.org/10.1016/s0306-4522(99)00486-8.

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20

McPhee, M. J., S. Harden, D. L. Robinson, R. W. Dicker, and V. H. Oddy. "Effects of backgrounding and finishing growth rates on P8 fat and intramuscular fat in Bos taurus steers." Animal Production Science 52, no. 5 (2012): 354. http://dx.doi.org/10.1071/an11184.

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The present study investigates the effects of backgrounding and finishing growth rates of Bos taurus steers grown out on three post-weaning growth pathways, across 4 years (1995–1998) on fat deposition. Scanned P8 fat at backgrounding exit (SP8exit), scanned P8 fat before slaughter (SP8sla) and carcass intramuscular fat (IMF, %) were evaluated. Four equations to predict SP8sla and four equations to predict carcass IMF across years were developed. Three post-weaning growth pathways (GPs) generated by different nutritional treatments across years were used in the study. Growth pathways were crea

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21

Karanam, Balasubramanyam, Ratish Gambhira, Shiwen Peng, et al. "Corrigendum to “Vaccination with HPV16 L2E6E7 fusion protein in GPI-0100 adjuvant elicits protective humoral and cell-mediated immunity” [Vaccine 27 (2009) 1040–1049]." Vaccine 32, no. 2 (2014): 309. http://dx.doi.org/10.1016/j.vaccine.2013.11.001.

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22

Pfeiffer, Ruth M., Joni L. Rutter, Mitchell H. Gail, Jeffery Struewing, and Joseph L. Gastwirth. "Efficiency of DNA pooling to estimate joint allele frequencies and measure linkage disequilibrium." Genetic Epidemiology 22, no. 1 (2001): 94–102. http://dx.doi.org/10.1002/gepi.1046.

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23

Wang, Yihong, Chahrzad Montrose-Rafizadeh, Lisa Adams, Margarita Raygada, Orna Nadiv, and Josephine M. Egan. "GIP regulates glucose transporters, hexokinases, and glucose-induced insulin secretion in RIN 1046-38 cells." Molecular and Cellular Endocrinology 116, no. 1 (1996): 81–87. http://dx.doi.org/10.1016/0303-7207(95)03701-2.

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24

Moin, Victor, and Shlomo A. Sharlin. "General Family Image in Intercultural Transition: Soviet Immigrant Families in Israel." Families in Society: The Journal of Contemporary Social Services 87, no. 2 (2006): 293–300. http://dx.doi.org/10.1606/1044-3894.3523.

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This article focuses on one of the important criteria in assessing one's family, namely, general family image (GFI), which directly connects to social comparison. General family image includes various representations about patterns, standards of family life, and couple relations. GFI also characterizes individual predispositions, as well as social cognition, and it plays essential epistemic and esteem maintenance functions in family life. This article examines GFI at both the theoretical and empirical levels, outlining the ways in which the concept can be utilized in the context of family stud

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25

Tardy, Brigitte, Kamel Haouchette, Patrick Mismetti, et al. "Long term prognosis of patients with myocardial infarction and normal coronary angiography: impact of inherited coagulation disorders." Thrombosis and Haemostasis 91, no. 02 (2004): 388–93. http://dx.doi.org/10.1160/th03-07-0442.

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SummaryThe prognosis of patients with myocardial infarction (MI) and normal coronary arteries (NCA) in the presence of an inherited coagulation disorder is unknown. The purpose of this study was to compare the clinical thrombosis outcome of patients with (GpI) or without (GpII), inherited coagulation disorders, who suffered from an acute MI with NCA. Eighty two consecutive patients (mean age 49 ± 15 years; 29 females) with MI, but NCA, were recruited. Twelve patients (15%) had an inherited coagulation disorder. GpI and GpII were statistically similar regarding age (45 ± 11 vs 50 ± 16 years-old

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26

Zhou, Wei, Dayong Tan, Wansheng Xiao, et al. "Structural properties of PbVO3perovskites under hydrostatic pressure conditions up to 10.6 GPa." Journal of Physics: Condensed Matter 24, no. 43 (2012): 435403. http://dx.doi.org/10.1088/0953-8984/24/43/435403.

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27

Witt, Karsten, and Bettina Möller. "Behandlung des Morbus Parkinson: Neuropsychologische Veränderungen nach Tiefer Hirnstimulation." Zeitschrift für Neuropsychologie 25, no. 1 (2014): 39–47. http://dx.doi.org/10.1024/1016-264x/a000112.

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Die Tiefenhirnstimulation (THS) ist beim Morbus Parkinson eine der effektivsten Therapieoptionen. Präoperativ wird nach einer dementiellen Entwicklung und nach Störungen in den Exekutivfunktionen gesucht, da letztere nach der Operation eine milde Verschlechterung erfahren können. Während neuropsychologische Veränderungen nach der VIM Stimulation nicht beobachtet werden, können leichte Defizite in der exekutiven Kontrolle nach der STN und der GPi Stimulation auftreten. Diese kognitiven Veränderungen haben keinen Einfluss auf die deutliche Besserung der Lebensqualität der Patienten durch die Ope

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28

Stringham, Heather M., and Michael Boehnke. "Lod scores for gene mapping in the presence of marker map uncertainty." Genetic Epidemiology 21, no. 1 (2001): 31–39. http://dx.doi.org/10.1002/gepi.1016.

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29

Seltman, Howard, Kathryn Roeder, and B. Devlin. "Evolutionary-based association analysis using haplotype data." Genetic Epidemiology 25, no. 1 (2003): 48–58. http://dx.doi.org/10.1002/gepi.10246.

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30

George, Varghese, and Purushottam W. Laud. "A Bayesian approach to the transmission/disequilibrium test for binary traits." Genetic Epidemiology 22, no. 1 (2001): 41–51. http://dx.doi.org/10.1002/gepi.1042.

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31

Greenberg, David A., and Paula C. Abreu. "Determining trait locus position from multipoint analysis: Accuracy and power of three different statistics." Genetic Epidemiology 21, no. 4 (2001): 299–314. http://dx.doi.org/10.1002/gepi.1036.

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32

Deng, Hong-Wen, Michael C. Mahaney, Jeff T. Williams, et al. "Relevance of the genes for bone mass variation to susceptibility to osteoporotic fractures and its implications to gene search for complex human diseases." Genetic Epidemiology 22, no. 1 (2001): 12–25. http://dx.doi.org/10.1002/gepi.1040.

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33

Liu, Ying, David Tritchler, and Shelley B. Bull. "A unified framework for transmission-disequilibrium test analysis of discrete and continuous traits." Genetic Epidemiology 22, no. 1 (2001): 26–40. http://dx.doi.org/10.1002/gepi.1041.

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34

Devlin, B., Bobby L. Jones, Silviu-Alin Bacanu, and Kathryn Roeder. "Mixture models for linkage analysis of affected sibling pairs and covariates." Genetic Epidemiology 22, no. 1 (2001): 52–65. http://dx.doi.org/10.1002/gepi.1043.

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35

Zhang, Shuanglin, and Hongyu Zhao. "Linkage disequilibrium mapping with genotype data." Genetic Epidemiology 22, no. 1 (2001): 66–77. http://dx.doi.org/10.1002/gepi.1044.

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36

Bacanu, Silviu-Alin, B. Devlin, and Kathryn Roeder. "Association studies for quantitative traits in structured populations." Genetic Epidemiology 22, no. 1 (2001): 78–93. http://dx.doi.org/10.1002/gepi.1045.

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37

Butters, Meryl A., Robert A. Sweet, Benoit H. Mulsant, et al. "APOE is associated with age-of-onset, but not cognitive functioning, in late-life depression." International Journal of Geriatric Psychiatry 18, no. 12 (2003): 1075–81. http://dx.doi.org/10.1002/gps.1006.

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38

Dias, Amit, Ravi Samuel, Vikram Patel, Martin Prince, R. Parameshwaran, and E. S. Krishnamoorthy. "The impact associated with caring for a person with dementia: a report from the 10/66 Dementia Research Group's Indian network." International Journal of Geriatric Psychiatry 19, no. 2 (2004): 182–84. http://dx.doi.org/10.1002/gps.1016.

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39

Bosworth, Hayden B., Rachel M. Bartash, Maren K. Olsen, and David C. Steffens. "The association of psychosocial factors and depression with hypertension among older adults." International Journal of Geriatric Psychiatry 18, no. 12 (2003): 1142–48. http://dx.doi.org/10.1002/gps.1026.

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40

Levy, Raymond. "Alzheimer—The Life of a Physician and the Career of a Disease. Konrad Maurer and Ulrike Maurer. Translated by Neil Levi with Alistair Burns, 2003. Columbia University Press, Columbia, OH. Pages: 270.$49.50." International Journal of Geriatric Psychiatry 19, no. 5 (2004): 498–99. http://dx.doi.org/10.1002/gps.1036.

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41

Bin Li, Zhi, Sai Yin Ho, Wai Man Chan, et al. "Obesity and depressive symptoms in Chinese elderly." International Journal of Geriatric Psychiatry 19, no. 1 (2004): 68–74. http://dx.doi.org/10.1002/gps.1040.

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42

Barber, Mark, and David J. Stott. "Validity of the Telephone Interview for Cognitive Status(TICS) in post-stroke subjects." International Journal of Geriatric Psychiatry 19, no. 1 (2004): 75–79. http://dx.doi.org/10.1002/gps.1041.

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43

Kalbe, E., J. Kessler, P. Calabrese, et al. "DemTect: a new, sensitive cognitive screening test to support the diagnosis of mild cognitive impairment and early dementia." International Journal of Geriatric Psychiatry 19, no. 2 (2004): 136–43. http://dx.doi.org/10.1002/gps.1042.

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44

Vinkers, David J., Jacobijn Gussekloo, Max L. Stek, Rudi G. J. Westendorp, and Roos C. van der Mast. "The 15-item Geriatric Depression Scale(GDS-15) detects changes in depressive symptoms after a major negative life event. The Leiden 85-plus Study." International Journal of Geriatric Psychiatry 19, no. 1 (2004): 80–84. http://dx.doi.org/10.1002/gps.1043.

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45

de Vugt, Marjolein E., Fred Stevens, Pauline Aalten, et al. "Do caregiver management strategies influence patient behaviour in dementia?" International Journal of Geriatric Psychiatry 19, no. 1 (2004): 85–92. http://dx.doi.org/10.1002/gps.1044.

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46

Politis, Antonis M., Lawrence S. Mayer, Maria Passa, Antonis Maillis, and Constantine G. Lyketsos. "Validity and reliability of the newly translated Hellenic Neuropsychiatric Inventory(H-NPI) applied to Greek outpatients with Alzheimer's disease: a study of disturbing behaviors among referrals to a memory clinic." International Journal of Geriatric Psychiatry 19, no. 3 (2004): 203–8. http://dx.doi.org/10.1002/gps.1045.

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47

Burgmer, Markus, and Gereon Heuft. "Occurrence and treatment of post-traumatic stress disorder in an elderly patient after a traffic accident." International Journal of Geriatric Psychiatry 19, no. 2 (2004): 185–88. http://dx.doi.org/10.1002/gps.1047.

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48

Steinberg, Martin, Cynthia A. Munro, Quincy Samus, Peter V.Rabins, Jason Brandt, and Constantine G. Lyketsos. "Patient predictors of response to treatment of depression in Alzheimer's disease: the DIADS study." International Journal of Geriatric Psychiatry 19, no. 2 (2004): 144–50. http://dx.doi.org/10.1002/gps.1048.

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49

Davis, Heather S., and Kenneth Rockwood. "Conceptualization of mild cognitive impairment: a review." International Journal of Geriatric Psychiatry 19, no. 4 (2004): 313–19. http://dx.doi.org/10.1002/gps.1049.

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50

Brodsky, Robert, Hubert Schrezenmeier, Petra Muus, et al. "A Global Registry of Patients with Paroxysmal Nocturnal Hemoglobinuria." Blood 114, no. 22 (2009): 3007. http://dx.doi.org/10.1182/blood.v114.22.3007.3007.

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Abstract Abstract 3007 Poster Board II-983 Paroxysmal nocturnal hemoglobinuria (PNH) is a rare clonal hematopoietic stem cell disease characterized by complement-mediated hemolysis which can lead to life-threatening complications including thrombosis, kidney disease, and pulmonary hypertension. The natural history of PNH is highly variable and has previously been captured by retrospective assessment. However, the clinical presentation and prognosis of the disease has changed with the increased awareness of PNH, the increased use of more sensitive diagnostic tests, and the availability of new t

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