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Journal articles on the topic 'Graded doses'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Abu, O.D., I.O. Onoagbe, and E. Ekugum. "Hepatotoxicity of Graded Doses of Ethanol Extract of Dialium guineense Stem Bark in Wistar Rats." International Journal Of Pharmaceutical And Bio-Medical Science 02, no. 09 (2022): 347–52. https://doi.org/10.5281/zenodo.7074637.

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<strong>Aim</strong>: To investigate the hepatotoxicity of graded doses of ethanol extract of Dialium guineense stem bark in Wistar rats.    <strong>Materials and Methods:</strong> Adult male Wistar rats (n = 35), which weighed between 160 and 180 g (mean weight = 170 ± 10 g) were assigned to seven (7) groups (5 rats per group). Group I rats served as control, while those in groups II - VII received graded doses of extract (200 - 5000 mg/kg body weight, bwt) for 28 days. Liver function tests (LFTs) were carried out.   <strong>Results:</strong> There were no significant di

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2

Mühlbachová, Gabriela, Pavel Čermák, Radek Vavera, et al. "Phosphorus Availability and Spring Barley Yields Under Graded P-Doses in a Pot Experiment." Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis 66, no. 1 (2018): 111–18. http://dx.doi.org/10.11118/actaun201866010111.

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The pot experiment with graded P doses was carried out in 2015 and 2016 in the Crop Research Institute, Prague – Ruzyně (undermentioned CRI). Three soil types were chosen for the experiment – Chernozem, Cambisol, Haplic Luvisol. The soils were treated by graded P doses (0.3–0.6–1.2 g P/5 kg of soil). The soil without any treatment served as a control. The spring barley (variety KWS Irina) was grown up to the milky ripeness stage. Plants were regularly watered with the deionised water. Two-year results of experiments showed that the increase of spring barley dry matter was noted under graded P

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3

Singh, A. B., L. Woodhouse, T. W. Storer, et al. "ALTERED RESPONSIVENESS OF OLDER MEN TO GRADED DOSES OF TESTOSTERONE." Journal of Investigative Medicine 52 (January 2004): S99. http://dx.doi.org/10.1097/00042871-200401001-00117.

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Singh, A. B., L. Woodhouse, T. W. Storer, et al. "Altered Responsiveness of Older Men to Graded Doses of Testosterone." Journal of Investigative Medicine 52, no. 1_suppl_part_1 (2001): 99. http://dx.doi.org/10.1177/108155890105201s117.

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5

Gabriel, Benjamin Ogunma, Christabel Osemudiame Uwaokhonye, and Emmanuel Ola Oshomoh. "Hepato-Safety Effect of the Poly-Herbal Aqueous Extract Using Animal Model." African Journal of Sciences and Traditional Medicine 1, no. 2 (2024): 458–69. https://doi.org/10.58578/ajstm.v1i2.3460.

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Poly-herbal formulation has been used all around the world due to its medicinal and therapeutic applications. These effects encompass mutual enhancement, mutual assistance, mutual restraint, and mutual antagonism.This research investigated the impact of a poly-herbal aqueous extract on the liver protective effect in Wistar rats. Plant samples were collected and processed into an extract. Twenty Wistar rats were divided into control group and graded doses (200, 400, and 800 mg/kg) of the poly-herbal aqueous extract. The rats were orally administered graded doses of the extract for 28 days. Vari

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6

Kaw, J. L., A. K. Khanna, M. Waseem, and S. Dogra. "Pulmonary response to graded doses of coal fly ash in rats." Journal of Environmental Science and Health . Part A: Environmental Science and Engineering 24, no. 7 (1989): 745–65. http://dx.doi.org/10.1080/10934528909375514.

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7

Singh, A. B., L. Woodhouse, T. W. Storer, et al. "117 ALTERED RESPONSIVENESS OF OLDER MEN TO GRADED DOSES OF TESTOSTERONE." Journal of Investigative Medicine 52, Suppl 1 (2004): S99.2—S99. http://dx.doi.org/10.1136/jim-52-suppl1-117.

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8

Ren, Jiaqian, Haibo Xu, Ji-Kyung Choi, Bruce G. Jenkins, and Y. Iris Chen. "Dopaminergic response to graded dopamine concentration elicited by four amphetamine doses." Synapse 63, no. 9 (2009): 764–72. http://dx.doi.org/10.1002/syn.20659.

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9

Kurpad, A. V., R. N. Kulkarni, M. L. Sheela, and P. S. Shetty. "Thermogenic responses to graded doses of noradrenaline in undernourished Indian male subjects." British Journal of Nutrition 61, no. 2 (1989): 201–8. http://dx.doi.org/10.1079/bjn19890109.

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1. Seventeen male subjects with an energy intake of 10.6 (sd 1.7) MJ/d and ten male undernourished labourers with an energy intake of 8.0 (sd 1.2) MJ/d were studied. The controls were subdivided into ten underweight controls with a body mass index (weight/height2; BMI) < 18 (17.2 (sd 0.9)) and seven normal-weight controls with a BMI > 20 (21.3 (sd 1.6)), while the undernourished labourers had a BMI < 18 (16.8 (sd 1.2)).2. Comparison of thermogenic responses to increasing doses of noradrenaline showed no overall significant inter-group differences when subjected to a nested analysis of

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10

Holst, N., T. G. Jenssen, P. G. Burhol, and E. Haug. "The effects of secretin on prolactin, estradiol, vasoactive intestinal polypeptide, and somatostatin levels in women." Acta Endocrinologica 122, no. 3 (1990): 313–18. http://dx.doi.org/10.1530/acta.0.1220313.

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Abstract. The effect of graded doses of intravenous secretin (0.5, 1.0, and 2.0 CU · kg−1 · h−1) on serum prolactin and estradiol levels, as well as plasma vasoactive intestinal polypeptide and somatostatin levels was studied in 6 normally cycling and healthy women, and compared with the hormone levels obtained by a control infusion with physiologic saline (0.15 mol/l). A significant decrease in serum prolactin concentrations was found with increasing doses of secretin at steady-state levels of plasma secretin (+30 to +60 min). A significant negative correlation (p<0.007, r=−0.2764) existed

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11

Okediran, B. S., A. S. Adah, F. Sanusi, and K. Y. Suleiman. "Lipid changes in male Albino rats exposed to graded doses of Lead." Ceylon Journal of Science 47, no. 2 (2018): 159. http://dx.doi.org/10.4038/cjs.v47i2.7512.

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12

Omoirri Moses Aziakpono, Uyovwiesevwa Ataihire Johnson, Orji Uchechukwu Harrison, et al. "Alcohol and Glucose D consumption decreases grip muscle strengths in graded doses." International Journal of Science and Research Archive 4, no. 1 (2021): 039–46. http://dx.doi.org/10.30574/ijsra.2021.4.1.0176.

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Alcohol, Blood Sugar, and Grip muscle strengths (GMS) may play key role in injury prevention and rehabilitation. In many cases, strengthening of the grip has been a prescription for rehabilitation from injuries such as golf and tennis elbow. In this study, the effects of alcohol and glucose consumption on grip muscle strength in early adult male subject was investigated. A total of thirty (200) human subjects of about18+ years old were recruited for the study. The subjects were administered varying doses of alcohol and glucose D, then allowed to rest for a period of 5 and 10 minutes before ass

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13

Brodkin, Marc A., Martin P. Simon, Andrea M. DeSantis, and Kevin J. Boyer. "Response of Rana pipiens to Graded Doses of the Bacterium Pseudomonas aeruginosa." Journal of Herpetology 26, no. 4 (1992): 490. http://dx.doi.org/10.2307/1565128.

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14

Mikus, Catherine R., Timothy S. Church, Conrad P. Earnest, Angela M. Thompson, and Steven N. Blair. "Graded Doses of Exercise and Insulin Resistance in Nondiabetic Post-Menopausal Women." Medicine & Science in Sports & Exercise 39, Supplement (2007): S236. http://dx.doi.org/10.1249/01.mss.0000273899.53513.4c.

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15

Rajkumar, L., and G. S. Sreenivasa Murthy. "Microfilariae recurrence in graded murrah buffalo treated with repeated doses of ivermectin." Journal of Parasitic Diseases 39, no. 2 (2013): 262–63. http://dx.doi.org/10.1007/s12639-013-0332-3.

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16

Bernardi, M., Paola E. D'Intino, F. Trevisani, et al. "Effects of prolonged ingestion of graded doses of licorice by healthy volunteers." Life Sciences 55, no. 11 (1994): 863–72. http://dx.doi.org/10.1016/0024-3205(94)90042-6.

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17

Harada, Seiki, Tsutomu Imaizumi, Michiko Momohara, Hiroyuki Masaki, Shin-Ichi Ando, and Akira Takeshita. "Arginine vasopressin attenuates phenylephrine-induced forearm vasoconstriction in men." Clinical Science 81, no. 6 (1991): 733–37. http://dx.doi.org/10.1042/cs0810733.

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1. The aim of this study was to examine whether arginine vasopressin modulates the vasoconstricting action of phenylephrine in human forearms. 2. In seven healthy subjects, we determined the percentage increases in forearm vascular resistance evoked by intra-arterial infusion of phenylephrine at graded doses during simultaneous intra-arterial infusion of saline or arginine vasopressin at two doses. Similarly, in another seven subjects, we examined the effects of intra-arterial infusions of saline or angiotensin II on the vasoconstricting action of intra-arterial phenylephrine. 3. Arginine vaso

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18

Green, Daniel M., Mingjuan Wang, Matthew J. Krasin, et al. "Renal function after treatment for childhood cancer: A report from the St. Jude Lifetime Cohort Study." Journal of Clinical Oncology 37, no. 15_suppl (2019): 10048. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.10048.

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10048 Background: We assessed renal function in a large, clinically assessed cohort of childhood cancer survivors. Methods: Creatinine and qualitative urine protein was measured in 2753 survivors (>10 years (years) post-diagnosis, age ≥18 years). Renal function was graded per the Kidney Disease International Global Outcomes 2012 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease (CKD). Multivariable logistic regression was used to estimate associations between demographics, treatment exposures, and CKD (grades 1-5 and 3-5). Radiation treatment was expres

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19

Rumahorbo, Cheryl Grace Pratiwi, Syafruddin Ilyas, Salomo Hutahaean, Cut Fatimah Zuhra, and Putri Cahaya Situmorang. "Chronic toxicity assessment of nano-formulated Bischofia javanica leaves: Implications for pharmacological use." Pharmacia 70, no. 4 (2023): 1101–9. http://dx.doi.org/10.3897/pharmacia.70.e110640.

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This study explores the chronic toxicity of nano-formulated Bischofia javanica leaves, a plant with pharmacological significance in Indonesia, following OECD guidelines 452. Graded doses (2, 4, 6, and 8 g/kg BW) of nano-formulated Bischofia javanica were administered to the treatment groups for 60 days, while the control group (K-) received only water. On the 61st day, the mice were euthanized, and samples for biochemical, hematological, and histopathological analysis were collected. Statistical analysis involved one-way ANOVA and Tukey’s post hoc tests. Graded doses of nano-formulated Bischof

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20

Rumahorbo, Cheryl Grace Pratiwi, Syafruddin Ilyas, Salomo Hutahaean, Zuhra Cut Fatimah, and Putri Cahaya Situmorang. "Chronic toxicity assessment of nano-formulated Bischofia javanica leaves: Implications for pharmacological use." Pharmacia 70, no. (4) (2023): 1101–9. https://doi.org/10.3897/pharmacia.70.e110640.

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This study explores the chronic toxicity of nano-formulated <i>Bischofia javanica</i> leaves, a plant with pharmacological significance in Indonesia, following OECD guidelines 452. Graded doses (2, 4, 6, and 8 g/kg BW) of nano-formulated <i>Bischofia javanica</i> were administered to the treatment groups for 60 days, while the control group (K-) received only water. On the 61st day, the mice were euthanized, and samples for biochemical, hematological, and histopathological analysis were collected. Statistical analysis involved one-way ANOVA and Tukey's post hoc tests. Graded doses of nano-form

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21

Sanda, Kyari Abba, Umar Kyari Sandabe, Ibrahim Bulama, et al. "Phytochemistry and effects of Ethanol Leaf Extract of Meytenus senengalensis (Lam) on Castor-oil Induced Diarrhoea in Albino Rats." Sahel Journal of Veterinary Sciences 17, no. 1 (2020): 1–6. http://dx.doi.org/10.54058/saheljvs.v17i1.89.

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Abstract Meytenus senengalensis (Lam). Ethanol leaf extract was investigated for its phytochemical contents as well as anti-diarrhoea effects. The ethanol leaf extract which is normally used in folkloric medicine was subjected to qualitative phytochemical screening. Graded doses of the extract (200, 400 and 800 mg per kg) were administered orally to the three groups of rats (n = 5) before induction of diarrhoea with castor oil. Another two groups of animals were treated with normal saline (control) and loperamide, a conventional anti-diarrhoea drug respectively. Gastro-intestinal transit

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22

Okwakpam, FN, SI Omeodu, T. Odinga, and SN Ijeoma. "REPRODUCTIVE HORMONE CHANGES IN MALE WISTAR RATS ADMINISTERED GRADED DOSES OF Chromolaena odorata LEAF EXTRACT." International Journal of Recent Research in Life Sciences (IJRRLS) 10, no. 1 (2023): 33–40. https://doi.org/10.5281/zenodo.7701708.

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<strong>Abstract:</strong> The effect of ethanol extract of <em>Chromolaena odorata</em> on reproductive hormones and histology of the testes in adult male albino rats was investigated in this study. Twenty male albino rats weighing between 120-130g were used for this study. They were randomly divided into four (4) groups, n=5. Group 1 served as control group and administered with distilled water only. Groups 2, 3, and 4 were orally administered with 250mg/kg, 500mg/kg and 100mg/kg body weight (b.w) of the extract respectively.  At the end of experimental period of 14 days, the animals we

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23

S, SENDUR KUMARAN, NATARAJAN S, MUTHVEL I, and SATHIYAMURTHY V A. "Efficacy of graded doses of polymers on processing quality of tomato Cv. Co.3." Madras Agricultural Journal 88, june (2001): 298–99. http://dx.doi.org/10.29321/maj.10.a00343.

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A study was undertaken at Horiticultural College & Research Institute, Coimbatore in tomato cv. Co.3 to optimize graded dose hydrophylic polymers and its effect on quality parameters. A total of three hydrophylic polymers viz., Terra Cottem, Polyvinyl alcohol and Polyacrylamide were selected for the study. The treatment included six levels each of Terra Cottem (T, to T, at 1.5, 3.0, 4.5, 6.0, 7.5 and 9.0 g per plant). Polyvinyl alcohol (T, to T,, at 3.0, 6.0, 12.0, 15.0 and 18.0 per plant), Polyacrylamide (T, to Tis at 2.5, 5.0, 7.5, 10.0, 12.5 and 15.0 per plant) and control (T,, at one p

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24

Saraswati, Indah, Desy Armalina, Fadila Risang Ayu, and Ratna Damma Purnawati. "Effect of Tiger Shrimp Shell Extract (Penaeus monodon) on Monosodium Glutamate-Induced Mice." Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) 12, no. 3 (2023): 150–66. http://dx.doi.org/10.14710/dmj.v12i3.38767.

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Background: The shell is a part of the tiger shrimp (Penaeus monodon) body that often becomes waste and has not been utilized properly, but it contains secondary antioxidants that can prevent oxidative stress in the form of astaxanthin. Although several studies have examined the function of astaxanthin as an antioxidant, the role of it in tiger shrimp shells against hepar mice induced by monosodium glutamate (MSG) is not well knownObjective: to determine the effect of tiger shrimp shell extract in graded doses on the histopathological picture of hepatic mice induced by MSG.Methods: Extraction

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25

Abu, O.D., I.O. Onoagbe, and E. Ekugum. "Nephrotoxic Evaluation of Aqueous Stem Bark Extract of Dialium guineense in Normal Wistar Rats." International Journal Of Pharmaceutical And Bio-Medical Science 02, no. 09 (2022): 353–57. https://doi.org/10.5281/zenodo.7088704.

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The present study investigated the nephrotoxic effect of aqueous extract of Dialium guineense stem bark in normal Wistar albino rats. Thirty-five male rats were used. Graded doses of the extract ranging from 200 to 5000 mg/kg body weight, bwt, were administered to the test rats daily for twenty-eight days. The control rats received distilled water. Thereafter plasma levels of creatinine, urea, electrolytes and urease activity were determined. There were no significant differences in the concentrations of the measured renal parameters, when compared with control group (p > 0.05). These resul

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26

Hart, Josiah Soipiriala, and Oghenefego Michael Adheke. "EVALUATING CARDIOTOXICITY UPON CHRONIC ADMINISTRATION OF GRADED DOSES OF PENTAZOCINE IN WISTAR RATS." Egyptian Journal of Forensic Sciences and Applied Toxicology 24, no. 2 (2024): 73–78. http://dx.doi.org/10.21608/ejfsat.2024.276378.1323.

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27

Roberts, S. O., R. A. Robergs, and P. Montner. "EFFECTS OF ORAL DOSES OF SODIUM DICHLOROACETATE (DCA) DURING CONTINUOUS GRADED EXERCISE 1415." Medicine &amp Science in Sports &amp Exercise 29, Supplement (1997): 249. http://dx.doi.org/10.1097/00005768-199705001-01414.

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28

Paditz, K., H. Kluth, and M. Rodehutscord. "Relationship between graded doses of three microbial phytases and digestible phosphorus in pigs." Animal Science 78, no. 3 (2004): 429–38. http://dx.doi.org/10.1017/s1357729800058835.

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AbstractThe efficacy of three microbial phytases to increase the amount of digestible phosphorus (dP) was studied in pigs. A basal diet was prepared meeting the requirements of 30-kg pigs with the exception of P. Concentrations (in g/kg dry matter) were: P 2·9, phytate P 1·3, calcium (Ca) 6·9, and crude protein 208. Intrinsic phytase activity was below detection limit. Microbial phytase was supplemented from three sources (Aspergillus niger (Asp), Peniophora lycii (Pen), and consensus phytase (Con)) at the following levels (phytase units (FTU) per kg diet): 150, 300, 450, 600 and 900. Diets we

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29

MULLERSPAHN, F., S. MODELL, M. ACKENHEIL, A. BRACHNER, and G. KURTZ. "Elevated response of growth hormone to graded doses of apomorphine in schizophrenic patients." Journal of Psychiatric Research 32, no. 5 (1998): 265–71. http://dx.doi.org/10.1016/s0022-3956(98)00005-3.

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30

Hopman, Wim P. M., Peter J. S. M. Kerstens, Jan B. M. J. Jansen, Gerd Rosenbusch, and Cornelis B. H. W. Lamers. "Effect of graded physiologic doses of cholecystokinin on gallbladder contraction measured by ultrasonography." Gastroenterology 89, no. 6 (1985): 1242–47. http://dx.doi.org/10.1016/0016-5085(85)90639-0.

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31

Burchfield, David J., Mark P. Preziosi, Victor W. Lucas, and Jian Fan. "Effects of graded doses of epinephrine during asphxia-induced bradycardia in newborn lambs." Resuscitation 25, no. 3 (1993): 235–44. http://dx.doi.org/10.1016/0300-9572(93)90120-f.

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32

Nilsson, M., G. Engström, and L. E. Ericson. "Graded response in the individual thyroid follicle cell to increasing doses of TSH." Molecular and Cellular Endocrinology 44, no. 2 (1986): 165–69. http://dx.doi.org/10.1016/0303-7207(86)90059-6.

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33

Singh, N. D., A. K. Sharma, P. Dwivedi, Shafiqur Rahman, G. Jamuna, and L. Geeta Devi. "Clinicohaemato-biochemical changes in F0female Wistar rats fed with graded doses of citrinin." Indian Journal of Veterinary Pathology 39, no. 1 (2015): 30. http://dx.doi.org/10.5958/0973-970x.2015.00007.3.

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34

Peter, Achukwu U., Ufelle A. Silas, Onyekwelu C. Kenechukwu, Amadi N. Millicent, Achukwu O. Ngozika, and Amadi N. Francis. "EFFECTS OF STEM-BARK EXTRACT OF OKOUBAKA AUBREVILLIE ON SOME VISCERAL ORGANS OF WISTAR RATS." African Journal of Traditional, Complementary and Alternative Medicines 15, no. 3 (2018): 57. http://dx.doi.org/10.21010/ajtcamv15i3.7.

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Background: Over the past two decades, there has been a tremendous increase in the use of herbal medicine; however, these herbs have not been properly evaluated to ascertain their effect on the body organs. Materials and Methods: Effects of stem bark extract of Okoubaka aubrevillie on some visceral organs were investigated in Wistar rats. For acute toxicity testing, Wistar rats (n=16), grouped into 4, (A-D) orally received graded doses of Okoubaka aubrevillie extract and deaths recorded within 24 hours. For sub-acute study, Wistar rats (n=20) grouped into 5, (A-E) orally received graded

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35

Hofman, W. F., and I. C. Ehrhart. "Effects of cyclooxygenase inhibition on pulmonary vascular responses to serotonin." Journal of Applied Physiology 62, no. 3 (1987): 1192–200. http://dx.doi.org/10.1152/jappl.1987.62.3.1192.

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The vasopressor response to graded bolus doses (50–500 micrograms) of serotonin (5-hydroxytryptamine; 5-HT) was examined in the isolated canine lower left lung lobe (LLL) perfused at constant flow with autogenous blood before and after cyclooxygenase inhibition (COI). Lobar vascular resistance (LVR) was partitioned into pre- (Ra) and postcapillary (Rv) segments by venous occlusion with lobar blood volume changes monitored gravimetrically. Before COI, 5-HT produced transient, dose-dependent increases in pulmonary arterial pressure (Ppa) of 43.8 +/- 4.8–123.0 +/- 8.5% (n = 22) and simultaneous d

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36

Eze, Ukamaka U., Ifeanyi G. Eke, Aruh O. Anaga, et al. "Clinico-toxicological effects of ceftriaxone after intramuscular administration of graded doses in Basenji dogs." Tropical Journal of Pharmaceutical Research 20, no. 10 (2021): 2089–97. http://dx.doi.org/10.4314/tjpr.v20i10.12.

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Purpose: The recent ceftriaxone-induced anaemia and mortalities at the dose of 50 mg/kg in Veterinary Teaching Hospital, University of Nigeria prompted this study which sought to assess the clinicotoxicological effects of ceftriaxone (CFZ) after intramuscular administration of graded doses in Basenji dogs.Methods: The effects of CFZ on the haematological indices, physiological parameters, liver and kidney functions were assessed in 4 group of dogs (n = 4) designated A – D. They were given CFZ intramuscularly for 21 days at doses of 12, 25 and 50 mg/kg for groups A, B, C, respectively, while th

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37

Korhonen, M., A. Vanhatalo, T. Varvikko, and P. Huhtanen. "Responses to Graded Postruminal Doses of Histidine in Dairy Cows Fed Grass Silage Diets." Journal of Dairy Science 83, no. 11 (2000): 2596–608. http://dx.doi.org/10.3168/jds.s0022-0302(00)75153-8.

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38

Pradhan, PP, AK Dash, N. Panda, PK Samant, and AP Mishra. "Effect of graded doses of neem coated urea on productivity of low land rice." ORYZA- An International Journal on Rice 56, no. 1 (2019): 68. http://dx.doi.org/10.5958/2249-5266.2019.00010.9.

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39

Kumaran, S. Sendur, Natarajan S, and Muthuvel I. "Efficacy of graded doses of polymers on processing quality of tomato Cv. CO-3." Scientific Transactions in Enviornment and Technovation 2, no. 1 (2008): 28–30. http://dx.doi.org/10.20894/stet.116.002.001.006.

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40

Huang, Yuguang, W. H. Yip, Scott W. McJames, and K. C. Wong. "INFLUENCE OF LACTIC-AND HYDROCHLORIC-ACIDOSIS ON CARDIOVASCULAR RESPONSES TO GRADED DOSES OF EPINEPHRINE." Anesthesiology 77, Supplement (1992): A661. http://dx.doi.org/10.1097/00000542-199209001-00661.

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41

Osterberg, K. L., J. L. Schriefer, J. Kessler, C. A. Horswill, D. H. Passe, and R. Murray. "IS THERE A GRADED EFFECT OF INGESTING VARYING DOSES OF FRUCTOSE ON GI DISTRESS?" Medicine & Science in Sports & Exercise 35, Supplement 1 (2003): S212. http://dx.doi.org/10.1097/00005768-200305001-01171.

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42

Hansen, Diethelm, and Stefanie Hansen. "The Effects of Three Graded Doses of Meperidine for Spinal Anesthesia in African Men." Anesthesia & Analgesia 88, no. 4 (1999): 827–30. http://dx.doi.org/10.1213/00000539-199904000-00027.

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Coviello, Andrea D., Beth Kaplan, Kishore M. Lakshman, Tai Chen, Atam B. Singh, and Shalender Bhasin. "Effects of Graded Doses of Testosterone on Erythropoiesis in Healthy Young and Older Men." Journal of Clinical Endocrinology & Metabolism 93, no. 3 (2008): 914–19. http://dx.doi.org/10.1210/jc.2007-1692.

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Abstract Context: Erythrocytosis is a dose-limiting adverse effect of testosterone therapy, especially in older men. Objective: Our objective was to compare the dose-related changes in hemoglobin and hematocrit in young and older men and determine whether age-related differences in erythropoietic response to testosterone can be explained by changes in erythropoietin and soluble transferrin receptor (sTfR) levels. Design: We conducted a secondary analysis of data from a testosterone dose-response study in young and older men who received long-acting GnRH agonist monthly plus one of five weekly

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Gisbert, Enric, Roberto D. Sainz, and Silas S. O. Hung. "Glycemic responses in white sturgeon after oral administration of graded doses of d-glucose." Aquaculture 224, no. 1-4 (2003): 301–12. http://dx.doi.org/10.1016/s0044-8486(03)00264-3.

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Huang, Susie Shih-Yin, Anders Bjerring Strathe, James G. Fadel, Pinpin Lin, Tsung-Yun Liu, and Silas S. O. Hung. "Absorption, distribution, and elimination of graded oral doses of methylmercury in juvenile white sturgeon." Aquatic Toxicology 122-123 (October 2012): 163–71. http://dx.doi.org/10.1016/j.aquatox.2012.06.003.

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Sunshine, A., N. Z. Olson, I. Marrero, S. Tirado, and E. Laska. "Onset and Duration of Analgesia for Graded Doses of Ketoprofen in Postoperative Dental Pain." Clinical Pharmacology & Therapeutics 59, no. 2 (1996): 133. http://dx.doi.org/10.1038/sj.clpt.1996.30.

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Hansen, Diethelm, and Stefanie Hansen. "The Effects of Three Graded Doses of Meperidine for Spinal Anesthesia in African Men." Anesthesia & Analgesia 88, no. 4 (1999): 827–30. http://dx.doi.org/10.1097/00000539-199904000-00027.

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S, MAHIMAIRAJA, HELKIASH J, and GOPALSWAMY A. "LONG TERM EFFECT OF GRADED DOSES OF FERTILIZERS AND MANURES ON SOIL PHYSICAL CONDITIONS." Madras Agricultural Journal 73, june (1986): 340–47. http://dx.doi.org/10.29321/maj.10.a02280.

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Long form application of graded doses of NPK fertilizers did not have signi ficant influence on bulk density and porespace, but significantly influenced the hydraulic conductivity and to some extent the soil nagrogate parameters. The combined application of inorganic fertilizers with organic manures viz., FYM impro- ved the physical condition of soil by increasing the hydraulic conductivity, poro- sity and aggregation and reducing the bulkdensity of soils. The improvement in Physical condition of soil due to the combined application of inorganic fortilizers and organic manures was reflected in

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Bhat, GhulamMohammad, Sameena Bashir, ShabirAhmad Khanday, and LateefAhmad Wani. "Effects of graded doses of sildenafil citrate on liver microanatomy in male albino rats." National Journal of Clinical Anatomy 12, no. 2 (2023): 77. http://dx.doi.org/10.4103/njca.njca_229_22.

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Gopinandhan, T. N., B. B. Channabasamma, T. N. Sandeep, and N. Chandrashekar. "Influence of Graded Doses of Coffee Biochar on the Growth of Arabica Coffee Seedling." Asian Research Journal of Agriculture 18, no. 2 (2025): 174–84. https://doi.org/10.9734/arja/2025/v18i2692.

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Biochar is a porous and carbon-rich product obtained from the thermal disintegration of solid agricultural waste biomasses in an oxygen-limited atmosphere. In recent years, the subject of biochar has increasingly become popular worldwide due to its potential to improve soil fertility and several studies have demonstrated the benefits of soil application of biochar in various crops. However, reports on the application of biochar in coffee farming are rather very limited. Thus, a study was undertaken to assess the influence of biochar application on the growth of arabica coffee seedlings, specif

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