Academic literature on the topic 'Halothane'

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Journal articles on the topic "Halothane"

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Raines, Douglas E., and Katie B. McClure. "Halothane Interactions with Nicotinic Acetylcholine Receptor Membranes." Anesthesiology 86, no. 2 (1997): 476–86. http://dx.doi.org/10.1097/00000542-199702000-00023.

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Background Although it has been suggested that anesthetics alter protein conformational states by binding to nonpolar sites within the interior regions of proteins, the rate and extent to which anesthetics penetrate membrane proteins has not been characterized. The authors report the use of steady-state and stopped-flow spectroscopy to characterize the interactions of halothane with receptor membranes. Methods Steady-state and stopped-flow fluorescence spectroscopy was used to characterize halothane quenching of nicotinic acetylcholine receptor (nAcChoR)-rich membrane intrinsic fluorescence an
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Williams, J. H., M. Holland, J. C. Lee, C. W. Ward, and K. P. Davy. "Effects of BAY K 8644, nifedipine, and low Ca2+ on halothane and caffeine potentiation." Journal of Applied Physiology 71, no. 2 (1991): 721–26. http://dx.doi.org/10.1152/jappl.1991.71.2.721.

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The purpose of this investigation was to examine the effects of the Ca2+ agonist BAY K 8644 and the Ca2+ antagonist nifedipine on halothane- and caffeine-induced twitch potentiation of mammalian skeletal muscle. Muscle fiber bundles were taken from normal Landrace pigs and exposed to BAY K 8644 (10 microM), nifedipine (1 microM), and low Ca2+ media administered alone and in combination with halothane (3%) or with increasing concentrations of caffeine (0.5–8.0 mM). Both BAY K 8644 and halothane potentiated twitches by approximately 80%; when they were administered in combination, twitch potenti
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Crowder, Michael C., Laynie D. Shebester, and Tim Schedl. "Behavioral Effects of Volatile Anesthetics in Caenorhabditis elegans." Anesthesiology 85, no. 4 (1996): 901–12. http://dx.doi.org/10.1097/00000542-199610000-00027.

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Background The nematode Caenorhabditis elegans offers many advantages as a model organism for studying volatile anesthetic actions. It has a simple, well-understood nervous system; it allows the researcher to do forward genetics; and its genome will soon be completely sequenced. C. elegans is immobilized by volatile anesthetics only at high concentrations and with an unusually slow time course. Here other behavioral dysfunctions are considered as anesthetic endpoints in C. elegans. Methods The potency of halothane for disrupting eight different behaviors was determined by logistic regression o
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Mason, Peggy, Casey A. Owens, and Donna L. Hammond. "Antagonism of the Antinocifensive Action of Halothane by Intrathecal Administration of GABA-A Receptor Antagonists." Anesthesiology 84, no. 5 (1996): 1205–14. http://dx.doi.org/10.1097/00000542-199605000-00023.

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Background The hind brain and the spinal cord, regions that contain high concentrations of gamma-aminobutyric acid (GABA) and GABA receptors, have been implicated as sites of action of inhalational anesthetics. Previous studies have established that general anesthetics potentiate the effects of gamma-aminobutyric acid at the GABAA receptor. It was therefore hypothesized that the suppression of nocifensive movements during anesthesia is due to an enhancement of GABAA receptor-mediated transmission within the spinal cord. Methods Rats in which an intrathecal catheter had been implanted 1 week ea
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Hemmings, Hugh C., and Anna I. B. Adamo. "Activation of Endogenous Protein Kinase C by Halothane in Synaptosomes." Anesthesiology 84, no. 3 (1996): 652–62. http://dx.doi.org/10.1097/00000542-199603000-00021.

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Background Protein kinase C is a signal transducing enzyme that is an important regulator of multiple physiologic processes and a potential molecular target for general anesthetic actions. However, the results of previous studies of the effects of general anesthetics on protein kinase C activation in vitro have been inconsistent. Methods The effects of halothane on endogenous brain protein kinase C activation were analyzed in isolated rat cerebrocortical nerve terminals (synaptosomes) and in synaptic membranes. Protein kinase C activation was monitored by the phosphorylation of MARCKS, a speci
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Alkire, Michael T., Chris J. D. Pomfrett, Richard J. Haier, et al. "Functional Brain Imaging during Anesthesia in Humans." Anesthesiology 90, no. 3 (1999): 701–9. http://dx.doi.org/10.1097/00000542-199903000-00011.

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Background Propofol and isoflurane anesthesia were studied previously with functional brain imaging in humans to begin identifying key brain areas involved with mediating anesthetic-induced unconsciousness. The authors describe an additional positron emission tomography study of halothane's in vivo cerebral metabolic effects. Methods Five male volunteers each underwent two positron emission tomography scans. One scan assessed awake-baseline metabolism, and the other scan assessed metabolism during halothane anesthesia titrated to the point of unresponsiveness (mean +/- SD, expired = 0.7+/-0.2%
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VARMA, R. R., R. C. WHITESELL, and M. M. ISKANDARANI. "Halothane Hepatitis Without Halothane." Survey of Anesthesiology 30, no. 4 (1986): 205. http://dx.doi.org/10.1097/00132586-198608000-00027.

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Conn, Harold O., and Jonas Skornicki. "Halothane hepatitis sans halothane." Hepatology 5, no. 6 (1985): 1238–40. http://dx.doi.org/10.1002/hep.1840050631.

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SATHER, A. P., A. L. SCHAEFER, A. K. W. TONG, C. GARIÉPY, and S. M. ZAWADSKI. "MUSCLE AND RECTAL TEMPERATURE RESPONSE CURVES TO A SHORT-TERM HALOTHANE CHALLENGE IN EIGHT-WEEK-OLD PIGLETS WITH KNOWN GENOTYPE AT THE HALOTHANE LOCUS." Canadian Journal of Animal Science 70, no. 1 (1990): 9–14. http://dx.doi.org/10.4141/cjas90-002.

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Each of the three genotypes (NN: normal, halothane negative; Nn: carrier, halothane negative; nn: halothane sensitive) at the halothane locus had a significantly different muscle temperature response curve to a 3-min halothane challenge, while only halothane positive (H+) and negative H−) phenotypes could be distinguished on the basis of the rectal temperature response curves. However, the among animal variation precludes its use as a diagnostic tool for the identification of heterozygous and homozygous normal among halothane negative pigs. Key words: Temperature, halothane gene, swine, genoty
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Spencer, G. E., N. I. Syed, K. Lukowiak, and W. Winlow. "Halothane-induced synaptic depression at both in vivo and in vitro reconstructed synapses between identified Lymnaea neurons." Journal of Neurophysiology 74, no. 6 (1995): 2604–13. http://dx.doi.org/10.1152/jn.1995.74.6.2604.

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1. In the present study we tested the ability of the general anesthetic, halothane, to affect synaptic transmission at in vivo and in vitro reconstructed peptidergic synapses between identified neurons of Lymnaea stagnalis. 2. An identified respiratory interneuron, visceral dorsal 4 (VD4), innervates a number of postsynaptic cells in the central ring ganglia of Lymnaea. Because VD4 has previously been shown to exhibit immunoreactivity for FMRFamide-related peptides, it was hypothesized that these peptides may be utilized by VD4 during synaptic transmission. In the intact, isolated CNS of Lymna
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Dissertations / Theses on the topic "Halothane"

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Provenat, Véronique. "Les effets toxiques et allergiques de l'halothane." Paris 5, 1989. http://www.theses.fr/1989PA05P046.

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Zhang, Ke. "Cardiac electrophysiology and cardiotoxicity of halothane /." The Ohio State University, 1989. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487676261012213.

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Knight, Trudy Lynn. "The molecular basis of halothane-induced hepatotoxicity." Thesis, Imperial College London, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321782.

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Siadat, Pajouh Majid 1959. "GENERATION OF HALOTHANE INDUCED ANTIBODY IN GUINEA PIGS AND ITS POSSIBLE ROLE IN THE PATHOGENESIS OF HALOTHANE INDUCED LIVER INJURY." Thesis, The University of Arizona, 1986. http://hdl.handle.net/10150/276363.

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LAUNAY, FREDERIC. "Toxicologie de l'halothane." Strasbourg 1, 1991. http://www.theses.fr/1991STR15020.

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Molliex, Serge. "Effets de l'halothane sur les pneumocytes II de rat en culture primaire." Saint-Etienne, 1991. http://www.theses.fr/1991STET6417.

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Vinh, Vu Huu. "Comparative contractile effects of halothane and sevoflurane in rat aorta." Kyoto University, 2001. http://hdl.handle.net/2433/150545.

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Goddard, Helen. "Electrophysiological effects of fentanyl, halothane and isoflurane on guinea-pig isolated ventricular myocytes." Thesis, University of Oxford, 2002. http://ora.ox.ac.uk/objects/uuid:58f6f4e2-aaa9-4913-a7c2-5568e2f8d72f.

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Torske, Kristine E. "An evaluation of epidural oxymorphone and bupivacaine during halothane anesthesia in dogs." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape16/PQDD_0026/NQ31906.pdf.

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Darling, John R. "The effects of halothane, isoflurane and sevoflurane on hepatic and renal function." Thesis, Queen's University Belfast, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.261937.

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Books on the topic "Halothane"

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Fisher, P. J. Halothane and membrane-bound enzymes. University of Birmingham, 1986.

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Hunt, Philip Andrew. The effect of halothane on phosphatidylcholine hydrolysis in rat cerebral cortex. University of Birmingham, 1987.

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Phillips, Marina. Leistungspsychologische und elektroenzephalographische Vigilanzmessungen der unmittelbaren postoperativen Phase nach standardisierten Inhalationsnarkosen mit Isofluran und Halothan. [s.n.], 1989.

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Gerdes, Christoph. Die Rolle des Serotoninsystems bei der Induktion der durch Halothan ausgelösten malignen Hyperthermie beim Schwein. [s.n.], 1992.

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Schurian, Felicitas. Zum Einsatz von Sevofluran beim Syrischen Goldhamster (Mesocricetus auratus) - eine Vergleichsstudie zu Halothan und Isofluran. Hieronymus, 2000.

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Prüssmann, Joachim. Einfluss einer Prämedikation mit Diazepam oder Promethazin auf die Biotransformation von Halothan beim Menschen und bei der Ratte. [s.n.], 1985.

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Breisgau, Universität Freiburg im, ed. Der Einfluss von Halothan und Isofluran auf die Blutfliessgeschwindigkeit in der Arteria cerebri media, gemessen mit der Transkraniellen Dopplersonographie. [s.n.], 1992.

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Laichinger, Andreas Hermann. Hepatotoxizität von Halothan: Gaschromatographische Analyse der Atemgase sowie histologische und enzymhistochemische Untersuchungen an der Rattenleber nach Halothanexposition unter normoxischen und hypoxischen Bedingungen. [s.n.], 1988.

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Zur Herzwirkung Von Inhalationsanaesthetica: Der Isolierte Katzenpapillarmuskel Als Myokard-Modell. Springer London, Limited, 2013.

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Mitchel, Marnie. Sevoflurane versus halothane for pediatric ent surgeries: Is the difference clinically significant for patients? 1997.

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Book chapters on the topic "Halothane"

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Maxwell, Robert A., and Shohreh B. Eckhardt. "Halothane." In Drug Discovery. Humana Press, 1990. http://dx.doi.org/10.1007/978-1-4612-0469-5_22.

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Gut, Josef. "Molecular Basis of Halothane Hepatitis." In Archives of Toxicology. Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-642-46856-8_1.

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Webb, A. J., O. I. Southwood, and S. P. Simpson. "The Halothane Test in Improving Meat Quality." In Evaluation and Control of Meat Quality in Pigs. Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-009-3301-9_23.

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Ahern, C. P., W. E. Rempel, J. H. Milde, and G. A. Gronert. "Porcine Malignant Hyperthermia: Dose/Response to Halothane." In Evaluation and Control of Meat Quality in Pigs. Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-009-3301-9_28.

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Pohl, Lance R., David Thomassen, Neil R. Pumford, et al. "Hapten Carrier Conjugates Associated with Halothane Hepatitis." In Advances in Experimental Medicine and Biology. Springer New York, 1991. http://dx.doi.org/10.1007/978-1-4684-5877-0_12.

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Mosteller, Frederick. "The Safety of Anesthetics: The National Halothane Study." In The Pleasures of Statistics. Springer New York, 2009. http://dx.doi.org/10.1007/978-0-387-77956-0_5.

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Bosnjak, Zeljko J., Sumio Hoka, Lawrence Turner, and John P. Kampine. "Cardiac Protection by Halothane Following Ischemia and Calcium Paradox." In Cell Calcium Metabolism. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4684-5598-4_61.

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Fischer, K. "The Importance of Reaction Intensity in the Halothane Test." In Evaluation and Control of Meat Quality in Pigs. Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-009-3301-9_29.

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Kathirvel, Paramasivam, and Alan L. Archibald. "The Halothane Gene, Leanness and Stress Susceptibility in Pigs." In Animal Models — Disorders of Eating Behaviour and Body Composition. Springer Netherlands, 2001. http://dx.doi.org/10.1007/978-94-015-9662-6_10.

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Arroyo, J. L., E. Dawson, R. P. Reiner, E. Gonima, and F. Carrascosa. "Effect of Isoflurane and Halothane on the Endocrine System." In Isoflurane. Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-71230-2_49.

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Conference papers on the topic "Halothane"

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Vijayan, Sujith, ShiNung Ching, Patrick L. Purdon, Emery N. Brown, and Nancy J. Kopell. "Biophysical modeling of alpha rhythms during halothane-induced unconsciousness." In 2013 6th International IEEE/EMBS Conference on Neural Engineering (NER). IEEE, 2013. http://dx.doi.org/10.1109/ner.2013.6696130.

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Sharma, Ashutosh, Sara E. Wilson, and Rob J. Roy. "EEG classification for estimating anesthetic depth during halothane anesthesia." In 1992 14th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 1992. http://dx.doi.org/10.1109/iembs.1992.5761515.

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Sharma, Wilson, and Roy. "EEG Classification For Estimating Anesthetic Depth During Halothane Anesthesia." In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 1992. http://dx.doi.org/10.1109/iembs.1992.592726.

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Letourneau, J. E., and R. Denis. "Variations of horizontal phoria at near during recovery from general anesthesia." In OSA Annual Meeting. Optica Publishing Group, 1988. http://dx.doi.org/10.1364/oam.1988.mr41.

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The purpose of the study was to evaluate recovery from general anesthesia in a day-care surgery unit. A group of forty-three patients underwent surgery under general anesthesia with enflurane (N = 14), isoflurane (N = 10), or halothane (N = 19). Anesthesia lasted 20-95 min (average, 45.3 min). Heterophoria was measured with the Maddox Wing; results are expressed in prism diopters. Patients were measured before anesthesia (condition 1) 1.5, 2.5, and 3.5 h after the end of anesthesia (conditions 2, 3, and 4).
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Pluháčková, Kristýna, Pavel Hobza, Theodore E. Simos, and George Maroulis. "Theoretical Investigation of the Unexpected Red Shift in the Halothane[ellipsis (horizontal)]Acetone Complex." In COMPUTATIONAL METHODS IN SCIENCE AND ENGINEERING: Theory and Computation: Old Problems and New Challenges. Lectures Presented at the International Conference on Computational Methods in Science and Engineering 2007 (ICCMSE 2007): VOLUME 1. AIP, 2007. http://dx.doi.org/10.1063/1.2835999.

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Van Reempts, J., B. Van Deuren, M. Borqers, and F. De Clerck. "R 68 070, A COMBINED TXA2-SYNTHETASE/TXA2-PROSTAGLANDIN ENDOPEROXIDE RECEPTOR INHIBITOR. REDUCES CEREBRAL INFARCT SIZE AFTER PHOTOCHEMICALLY INITIATED THROMBOSIS IN SPONTANEOUSLY HYPERTENSIVE RATS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643470.

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The effects of R 68 070, an oxime-alkane carboxylic acid derivative combining specific thromboxane A2 (TXA2) synthetase inhibition with TXA2/prostaglandin endoperoxide receptor blockade in one molecule, were investigated in a model of photochemically induced stroke in spontaneously hypertensive rats.Each experimental group was compared with an untreated control group. All animals were anesthetized with halothane in N20/02 and artificially ventilated. After incision of the scalp and stereotaxic positioning of a fibre optic light source, halothane was discontinued. When physiological variables r
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B. Maljković, Jelena, Jelena Vukalović, Francisco Blanco, Gustavo García, and Bratislav P. Marinković. "Experimental and theoretical investigation of electron interaction with molecules." In International scientific conference: Meeting on new trends in Astronomy & Earth Observation. Scientific Society Isaac Newton Belgrade, 2024. https://doi.org/10.69646/aob241217.

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Abstract: In response to escalating concerns regarding the environmental implications of anesthetic compounds on both global warming and ozone layer degradation, a rigorous investigation combining theoretical and experimental methodologies was conducted to elucidate the elastic electron scattering dynamics of halothane, sevoflurane, and isoflurane. These anesthetic gases, which are predominantly excreted into the atmosphere without degradation post-use, contribute to increasing concentrations of halogenated compounds that possess both elevated Global Warming Potentials (GWP) and significant Oz
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Borges, Marcos C., Cinzia L. Marchica, Venkatesan Narayanan, and Mara S. Ludwig. "Effect Of Allergen Challenge Under Isoflurane And Halothane Anesthesia In Hyperresponsiveness And Inflammation In A Murine Model Of Allergic Asthma." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a2882.

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Maljković, J. B., B. P. Marinković, and J. Kopyra. "Dissociative electron attachment to isoflurane molecule in the gas phase." In International Meeting on Data for Atomic and Molecular Processes in Plasmas: Advances in Standards and Modelling. Institute of Physics Belgrade, 2024. https://doi.org/10.69646/aob241124.

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Common halogenated anesthetic gases include halothane, isoflurane, sevoflurane, and desflurane. These gases can have varying global warming potential (GWP) and environmental effects (Langbein et al 1999). Halogenated aneastetics also contribute to greenhouse gas emissions, although their impact varies based on their global warming potential GWP. We studied DEA to gas phase target by means of a crossed electron-molecular beam technique (Kopyra et al 2017). Dissociative electron attachment processes were investigated utilizing the crossed beam apparatus. In this technique the incident electron b
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ALKIRE, M. T., B. ROOZENDAAL, and L. CAHILL. "TOWARD THE NEUROANATOMIC BASIS OF ANAESTHETIC-INDUCED AMNESIA: HALOTHANE-INDUCED AMNESIA, UNLIKE DIAZEPAM-INDUCED AMNESIA, MAY NOT BE REVERSED WITH BILATERAL LESIONING OF THE BASOLATERAL AMYGDALA." In Proceedings of the Fourth International Symposium. PUBLISHED BY IMPERIAL COLLEGE PRESS AND DISTRIBUTED BY WORLD SCIENTIFIC PUBLISHING CO., 2000. http://dx.doi.org/10.1142/9781848160231_0040.

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Reports on the topic "Halothane"

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Kirby, Albert W., Alfred T. Townsend, Carolyn D. Pope, Robert E. Stafford, and Thomas H. Harding. Effects of Halothane Anesthesia on Blood Cholinesterase Activity in Cats. Defense Technical Information Center, 1989. http://dx.doi.org/10.21236/ada212053.

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Knight, Travis, Kenneth J. Stalder, Rodney Goodwin, Steven M. Lonergan, and Donald C. Beitz. Influence of Breed, Gender, and Halothane Genotype on Lipids of longissimus dorsi Muscle of Pigs. Iowa State University, 2004. http://dx.doi.org/10.31274/ans_air-180814-105.

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