Academic literature on the topic 'Hematopoiesis Regulation'

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Journal articles on the topic "Hematopoiesis Regulation"

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Nathan, David G. "Regulation of Hematopoiesis." Pediatric Research 27, no. 5 (May 1990): 423–31. http://dx.doi.org/10.1203/00006450-199005000-00001.

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Li, Haiyan, Jin Jin, shao-Cong Sun, and Stephanie S. Watowich. "Molecular Regulation of Adult Hematopoiesis By GATA-2." Blood 124, no. 21 (December 6, 2014): 4337. http://dx.doi.org/10.1182/blood.v124.21.4337.4337.

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Abstract GATA-2 is a zinc finger-containing transcriptional regulator that plays important roles in embryonic and adult hematopoiesis. Mutations in human GATA2 are associated with myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML), as well as immunodeficiency disorders that present with a profound loss of monocytes, dendritic cells and other myeloid lineage populations. Recent work reveals crucial roles for GATA-2 in definitive hematopoietic stem/progenitor cell activity, vascular integrity and lymphatic development. However, the molecular mechanisms by which GATA-2 controls adult
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Zon, LI. "Developmental biology of hematopoiesis." Blood 86, no. 8 (October 15, 1995): 2876–91. http://dx.doi.org/10.1182/blood.v86.8.2876.bloodjournal8682876.

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The cellular and environmental regulation of hematopoiesis has been generally conserved throughout vertebrate evolution, although subtle species differences exist. The factors that regulate hematopoietic stem cell homeostasis may closely resemble the inducers of embryonic patterning, rather than the factors that stimulate hematopoietic cell proliferation and differentiation. Comparative study of embryonic hematopoiesis in lower vertebrates can generate testable hypotheses that similar mechanisms occur during hematopoiesis in higher species.
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Zon, LI. "Developmental biology of hematopoiesis." Blood 86, no. 8 (October 15, 1995): 2876–91. http://dx.doi.org/10.1182/blood.v86.8.2876.2876.

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Abstract The cellular and environmental regulation of hematopoiesis has been generally conserved throughout vertebrate evolution, although subtle species differences exist. The factors that regulate hematopoietic stem cell homeostasis may closely resemble the inducers of embryonic patterning, rather than the factors that stimulate hematopoietic cell proliferation and differentiation. Comparative study of embryonic hematopoiesis in lower vertebrates can generate testable hypotheses that similar mechanisms occur during hematopoiesis in higher species.
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de Rooij, Laura P. M. H., Derek C. H. Chan, Ava Keyvani Chahi, and Kristin J. Hope. "Post-transcriptional regulation in hematopoiesis: RNA binding proteins take control." Biochemistry and Cell Biology 97, no. 1 (February 2019): 10–20. http://dx.doi.org/10.1139/bcb-2017-0310.

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Normal hematopoiesis is sustained through a carefully orchestrated balance between hematopoietic stem cell (HSC) self-renewal and differentiation. The functional importance of this axis is underscored by the severity of disease phenotypes initiated by abnormal HSC function, including myelodysplastic syndromes and hematopoietic malignancies. Major advances in the understanding of transcriptional regulation of primitive hematopoietic cells have been achieved; however, the post-transcriptional regulatory layer that may impinge on their behavior remains underexplored by comparison. Key players at
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Chen, Sisi, and Omar Abdel-Wahab. "Splicing regulation in hematopoiesis." Current Opinion in Hematology 28, no. 4 (May 10, 2021): 277–83. http://dx.doi.org/10.1097/moh.0000000000000661.

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QUESENBERRY, PETER J., IAN K. MCNIECE, H. ELIZABETH MCGRATH, DANIEL S. TEMELES, GWEN B. BABER, and DONNA H. DEACON. "Stromal Regulation of Hematopoiesis." Annals of the New York Academy of Sciences 554, no. 1 Molecular and (May 1989): 116–24. http://dx.doi.org/10.1111/j.1749-6632.1989.tb22414.x.

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Sashida, Goro, and Atsushi Iwama. "Epigenetic regulation of hematopoiesis." International Journal of Hematology 96, no. 4 (September 29, 2012): 405–12. http://dx.doi.org/10.1007/s12185-012-1183-x.

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North, Trista. "Regulation of vertebrate hematopoiesis." Experimental Hematology 53 (September 2017): S40. http://dx.doi.org/10.1016/j.exphem.2017.06.042.

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Wimmer, Antonia, Sophia K. Khaldoyanidi, Martin Judex, Naira Serobyan, Richard G. DiScipio, and Ingrid U. Schraufstatter. "CCL18/PARC stimulates hematopoiesis in long-term bone marrow cultures indirectly through its effect on monocytes." Blood 108, no. 12 (December 1, 2006): 3722–29. http://dx.doi.org/10.1182/blood-2006-04-014399.

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AbstractChemokines play a role in regulating hematopoietic stem cell function, including migration, proliferation, and retention. We investigated the involvement of CCL18 in the regulation of bone marrow hematopoiesis. Treatment of human long-term bone marrow cultures (LTBMCs) with CCL18 resulted in significant stimulation of hematopoiesis, as measured by the total number of hematopoietic cells and their committed progenitors produced in culture. Monocytes/macrophages, whose survival was almost doubled in the presence of CCL18 compared with controls, were the primary cells mediating this effec
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Dissertations / Theses on the topic "Hematopoiesis Regulation"

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Huang, Hsuan-Ting. "Epigenetic Regulation of Hematopoiesis in Zebrafish." Thesis, Harvard University, 2012. http://dissertations.umi.com/gsas.harvard:10175.

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The initiation of the hematopoietic program is orchestrated by key transcription factors that recruit chromatin regulators in order to activate or inhibit blood target gene expression. To generate a complete compendium of chromatin factors that establish the genetic code during developmental hematopoiesis, we conducted a large-scale reverse genetic screen targeting 425 chromatin factors in zebrafish and identified over 30 novel chromatin regulators that function at distinct steps of embryonic hematopoiesis. In vertebrates, developmental hematopoiesis occurs in two waves. During the first and p
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Ullrich, Sebastian 1984. "Alternative mechanisms of gene regulation during hematopoiesis." Doctoral thesis, Universitat Pompeu Fabra, 2018. http://hdl.handle.net/10803/665801.

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Gene regulation orchestrates the development of different cell types and organs from the same genetic blueprint. While the basic mode of gene regulation is driven by transcription factors, there are a variety of other mechanisms that determine the amount of RNA produced per genes. In this work we first investigate specifically intron retention as a mode of alternative splicing that alters the cellular transcriptomes. As a model, we use hematopoiesis. We compare intron retention in different stages of human and mouse B-cell development to granulocyte differentiation. We further explore expressi
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Durand, Ellen Marie. "Regulation of hematopoietic stem cell migration and function." Thesis, Harvard University, 2014. http://dissertations.umi.com/gsas.harvard:11550.

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Hematopoietic stem cell transplantation (HSCT) is an effective treatment for blood disorders and autoimmune diseases. Following HSCT, these cells must successfully migrate to the marrow niche and replenish the blood system of the recipient. This process requires both non-cell and cell-autonomous regulation of hematopoietic stem and progenitor cells (HSPCs). A transgenic reporter line in zebrafish allowed the investigation of factors that regulate HSPC migration and function. To directly observe cells in their endogenous microenvironment, confocal live imaging was used to track runx1:GFP+ HSP
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Martin, Richard. "Regulation of SCL expression and function in hematopoiesis." Thesis, McGill University, 2004. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=85582.

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The development of the hematopoietic system occurs in two waves: a first wave of primitive erythropoiesis, which consists in the production of a single lineage, primitive erythrocytes, and a second wave of definitive hematopoiesis, which describes the generation of many specialized blood cell types from common hematopoietic stem cells. Whereas definitive hematopoiesis is fairly well understood, involves signals from the environment and the expression of lineage-specific transcription factors, the molecular mechanisms regulating primitive erythropoiesis remain to be defined. The aim of t
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Smith, Molly. "Alternative Splicing and Regulation of Innate Immune Mediators in Normal and Malignant Hematopoiesis." University of Cincinnati / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1563527303459942.

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Gronthos, Stan. "Stromal precursor cells : purification and the development of bone tissue." Title page, contents and abstract only, 1998. http://web4.library.adelaide.edu.au/theses/09PH/09phg8757.pdf.

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Bibliography: leaves 152-223. Experiments were designed to identify and purify human bone marrow stromal precursor cells by positive immunoselection, based on the cell surface expression of the VCAM-1 and STRO-1 antigens. The data presented demonstrates a hierarchy of bone cell development in vitro.
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Gaboury, Louis A. "Studies of the role of mesenchymal cells in the regulation of hemopoiesis." Thesis, University of British Columbia, 1988. http://hdl.handle.net/2429/28784.

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Hemopoiesis is thought to be regulated in part by specific, but as yet undefined, interactions between primitive hemopoietic cells and fixed, non-hemopoietic marrow elements collectively referred to as the stroma. Recently, a marrow culture system has been described that allows the maintenance of primitive human hemopoietic progenitor cells for many weeks in the absence of exogenously added hemopoietic growth factors. The formation of a heterogeneous adherent layer in which many stromal elements are found appears to be important to the maintenance of hemopoiesis in this system. As part of the
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Serbanovic-Canic, Jovana. "Using zebrafish to identify new regulators of haematopoiesis." Thesis, University of Cambridge, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.607950.

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Rothberg, Janet L. "Polycomb-like 2 (Mtf2/Pcl2) is Required for Epigenetic Regulation of Hematopoiesis." Thesis, Université d'Ottawa / University of Ottawa, 2016. http://hdl.handle.net/10393/35323.

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Polycomb proteins are epigenetic regulators that are critical in mediating gene repression at critical stages during development. Core and accessory proteins make up the Polycomb Repressive Complex 2 (PRC2), which is responsible for trimethylation of lysine 27 on histone 3 (H3K27me3), leading to maintenance of chromatin compaction and sustained gene repression. Classically, Polycomb accessory proteins are often thought of as having minor roles in fine-tuning the repressive action of PRC2. Their actions have often been attributed to chromatin recognition, targeting to specific loci and enhancin
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Jarratt, Andrew. "Locus-wide studies into the transcriptional regulation of Runx1 in developmental hematopoiesis." Thesis, University of Oxford, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.572521.

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Developmental hematopoiesis sees the generation of the first blood cells and definitive blood during embryonic development. The founding cell of definitive hematopoiesis, the hematopoietic stem cell (HSC), gives rise to all adult blood :I: ]] 1:: t '.1 '4 !..:. : 1 1 '.! . lineages throughout the the life span or an orgamism. It IS expected that future ex-vivo manipulation ofHSCs for therapeutic uses will benefit from a thorough understanding of the mechanisms, both cellular and genetic, that give rise to HSCs. One of the most critical regulators of HSC emergence in the embryo is the transcrip
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Books on the topic "Hematopoiesis Regulation"

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1963-, Brown Geoffrey, and Ceredig Rhodri, eds. Cell determination during hematopoiesis. Hauppauge, NY: Nova Science Publishers, 2009.

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Brown, Geoffrey, and Rhodri Ceredig. Cell determination during hematopoiesis. New York: Nova Biomedical Books, 2009.

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G, I͡Ushkov B., та Bolʹshakov Vladimir Nikolaevich, ред. Reguli͡at͡sii͡a gemopoėza pri vozdeĭstvii na organizm ėkstremalʹnykh faktorov. Sverdlovsk: Akademii͡a nauk SSSR, Uralʹskoe otd-nie, 1988.

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Pezcoller Symposium on Normal and Malignant Hematopoiesis: New Advances (6th 1994 Rovereto, Italy). Normal and malignant hematopoiesis: New advances. New York: Plenum Press, 1995.

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Albert, Najman, and Université Pierre et Marie Curie. Faculté de médecine Saint-Antoine. Département d'hématologie., eds. The inhibitors of hematopoiesis =: Les inhibiteurs de l'hématopoïèse : proceedings of the First International Symposium on Inhibiting Factors in the Regulation of Hematopoiesis, Paris, (France), 26-28 April, 1987). [Paris]: INSERM, 1987.

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George, Stamatoyannopoulos, and Nienhuis Arthur W, eds. Developmental control of globin gene expression: Proceedings of the Fifth Conference on Hemoglobin Switching, held in Airlie, Virginia, September 28-October 1, 1986. New York: Liss, 1987.

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International Conference on Negative Regulation of Hematopoiesis (3rd 1993 Paris, France). The negative regulation of hematopoiesis: From fundamental aspects to clinical applications : Régulation négative de l'hématopïèse : des aspects fondamentaux à l'application clinique : proceedings of the third International Conference on Negative Regulation of Hematopoiesis, Paris, France, 18-22 April, 1993. Paris: Editions INSERM, 1993.

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D, Licht Jonathan, and Ravid Katya, eds. Transcription factors: Normal and malignant development of blood cells. New York: Wiley-Liss, 2001.

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Broxmeyer, Hal E. Cord blood: Biology, transplantation, banking, and regulation. Bethesda, Md: AABB Press, 2011.

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Mihich, Enrico, and Donald Metcalf. Normal and Malignant Hematopoiesis. Springer, 2012.

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Book chapters on the topic "Hematopoiesis Regulation"

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Weiss, Leon. "Cellular Regulation in Hematopoiesis." In The Reticuloendothelial System, 1–22. Boston, MA: Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-5158-0_1.

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Metcalf, Donald. "Regulation of Normal Hemopoiesis." In Normal and Malignant Hematopoiesis, 1–10. Boston, MA: Springer US, 1995. http://dx.doi.org/10.1007/978-1-4615-1927-0_1.

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Ogawa, Makio, and Fumiya Hirayama. "Cytokine Regulation of Lymphohemopoietic Progenitors." In Normal and Malignant Hematopoiesis, 11–14. Boston, MA: Springer US, 1995. http://dx.doi.org/10.1007/978-1-4615-1927-0_2.

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Mustjoki, Satu, Riitta Alitalo, and Antti Vaheri. "Role of Plasminogen Activation in Hematopoietic Malignancies and in Normal Hematopoiesis." In Plasminogen: Structure, Activation, and Regulation, 217–35. Boston, MA: Springer US, 2003. http://dx.doi.org/10.1007/978-1-4615-0165-7_13.

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Rameshwar, Pranela, and Pedro Gascón. "Neural Regulation of Hematopoiesis by the Tachykinins." In Molecular Biology of Hematopoiesis 5, 463–70. Boston, MA: Springer US, 1996. http://dx.doi.org/10.1007/978-1-4613-0391-6_56.

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Cantrell, D. A., M. Izquierdo, J. Nunes, N. Osman, K. Reif, and M. Woodrow. "The Regulation and Function of p21Ras in T Cell Activation and Growth." In Normal and Malignant Hematopoiesis, 61–76. Boston, MA: Springer US, 1995. http://dx.doi.org/10.1007/978-1-4615-1927-0_7.

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Miller, Alan M. "Lipoxygenase Metabolism in the Regulation of Hematopoiesis." In Prostaglandins, Leukotrienes, Lipoxins, and PAF, 339–51. Boston, MA: Springer US, 1991. http://dx.doi.org/10.1007/978-1-4899-0727-1_33.

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Link, Daniel C. "Regulation of Hematopoiesis by CXCL12/CXCR4 Signaling." In Targeted Therapy of Acute Myeloid Leukemia, 593–605. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1393-0_30.

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Coccia, Eliana Marina, Emilia Stellacci, Giovanna Marziali, Roberto Orsatti, Edvige Perrotti, Nicoletta Del Russo, Ugo Testa, and Angela Battistini. "Iron Regulation of Transferrin Receptor and Ferritin Expression in Differentiating Friend Leukemia Cells." In Molecular Biology of Hematopoiesis 5, 693–703. Boston, MA: Springer US, 1996. http://dx.doi.org/10.1007/978-1-4613-0391-6_84.

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Marziali, Giovanna, Edvige Perrotti, Ramona Ilari, Eliana M. Coccia, Ugo Testa, and Angela Battistini. "Transcriptional Regulation of the Ferritin H-Chain and Transferrin Receptor in Hematopoietic Cells." In Molecular Biology of Hematopoiesis 6, 391–402. Boston, MA: Springer US, 1999. http://dx.doi.org/10.1007/978-1-4615-4797-6_48.

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Conference papers on the topic "Hematopoiesis Regulation"

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Greenwood, Dalton L., and Jeffrey C. Rathmell. "Abstract PR07: Connecting acetate and citrate metabolism with epigenetic regulation of hematopoiesis." In Abstracts: AACR Special Virtual Conference on Epigenetics and Metabolism; October 15-16, 2020. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.epimetab20-pr07.

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Jiang, Qingfei, Maria Anna Zipeto, Nathan Delos Santos, Sheldon Morris, and Catriona Jamieson. "Abstract 299: RNA editing enzyme ADAR1 accelerates normal hematopoiesis cell cycle by regulation microRNA biogenesis." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-299.

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Lee, Jennifer, Jae-Hung Shieh, Jianxuan Zhang, Liren Liu, Giovanni Morrone, Malcolm A. S. Moore, and Pengbo Zhou. "Abstract 211: Ubiquitin-proteolytic regulation of hematopoietic stem cell expansion." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-211.

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Asch, Adam S., Maria J. Ruiz-Echevarria, Jared Whelan, Thomas Green, Biree Andemariam, Douglas Weidner, and Nance Hamel. "Abstract 4234: Translational regulation mediates hematopoietic progenitor cell generation in embryonic stem cell culture." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-4234.

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Wu, Siyuan, Tiangang Cui, and Tianhai Tian. "Mathematical Modelling of Genetic Network for Regulating the Fate Determination of Hematopoietic Stem Cells." In 2018 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2018. http://dx.doi.org/10.1109/bibm.2018.8621476.

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Dorokhina, Yu A., and G. F. Ryzhkova. "Morphological and biochemical parameters of blood in rabbits when using energymetabolic compositions." In SPbVetScience. FSBEI HE St. Petersburg SUVM, 2023. http://dx.doi.org/10.52419/3006-2022-7-18-23.

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Modern animal husbandry can no longer be imagined without special biologically active additives and a variety of protein, vitamin and mineral complexes. Among all additives, a special place is occupied by energy-metabolic compositions that give animals all the most necessary and important substances. The composition of the EC includes: yantaric acid is a universal intracellular metabolite, widely involved in metabolic reactions in the body; citric acid is the main intermediate product of the metabolic cycle of tricarboxylic acids, plays an important role in the system of biochemical reactions
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Grigoriou, M., P. Verginis, C. Nikolaou, P. Pavlidis, E. Dermitzakis, G. Bertsias, D. Boumpas, and A. Banos. "S4D:7 Next generation sequencing in hematopoietic progenitors of murine sle model reveals aberrant regulation of cebp/a expression." In 11th European Lupus Meeting, Düsseldorf, Germany, 21–24 March 2018, Abstract presentations. Lupus Foundation of America, 2018. http://dx.doi.org/10.1136/lupus-2018-abstract.26.

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Khella, Christen A., and Michael L. Gatza. "Abstract 5858: Multiplatform analyses identify upregulated hematopoietic cell kinase activity in poorly prognostic high-grade serous ovarian cancer and its role in regulating tumor aggressiveness." In Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.am2020-5858.

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Reports on the topic "Hematopoiesis Regulation"

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Taub, Floyd E., and Richard E. Weller. Proline-Rich Polypeptide 1 and GX-NH2: Molecular and Genetic Mechanisms of Hematopoiesis Regulation. Office of Scientific and Technical Information (OSTI), September 2011. http://dx.doi.org/10.2172/1025686.

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