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Dissertations / Theses on the topic 'Host-parasite'

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Published: 4 June 2021

Last updated: 26 July 2025

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1

Morgan, Andrew. "Experimental host-parasite coevolution." Thesis, University of Oxford, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.424864.

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2

Pollok, Richard. "Cryptosporidium parvum : host-parasite interactions." Thesis, Queen Mary, University of London, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.402442.

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3

Watson, Andrew Keith. "Characterising microsporidian host-parasite interactions." Thesis, University of Newcastle upon Tyne, 2016. http://hdl.handle.net/10443/3504.

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Microsporidia are an enormously successful group of obligate intracellular fungal parasites that infect most eukaryotes including humans. In my thesis I have analysed and compared microsporidian genomes to identify which genes have been conserved, and which lost, during the transition of the group to parasitism, sequenced the transcriptome of a mixed infection of Trachipleistophora hominis in a rabbit kidney cell line, and provided a description of the T. hominis intracellular lifecycle. My results demonstrate that microsporidian genome evolution is extremely dynamic; with huge loss of genes i

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4

Edwards, J. C. "Parasite-induced changes in host behaviour." Thesis, University of Nottingham, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.380108.

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5

Mohamemd-Ahmed, Ahmed Gaafar. "Parasite-host studies with Orobanche SPP." Thesis, University of Reading, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.262494.

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6

Bartley, Paul Murdoch. "Host-parasite interactions of Neospora caninum." Thesis, University of Edinburgh, 2017. http://hdl.handle.net/1842/23592.

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The papers included in this thesis examine the host–parasite relationship in small and large animals following experimental challenges with Neospora caninum. This apicomplexan parasite is a major cause of abortion and reproductive losses in cattle worldwide. Economic and welfare issues make the development of a vaccine against the transplacental transmission of Neospora highly desirable. This thesis evaluates the host-parasite interactions in a non-pregnant mouse model examining whether the actively multiplying stage of the parasite (tachyzoite) could be attenuated through prolonged in vitro c

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7

Dobbie, Samuel Thormond. "Ecological perspectives on host-parasite coevolution." Thesis, University of East Anglia, 2013. https://ueaeprints.uea.ac.uk/48681/.

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It is a truth universally acknowledged that polymorphism at host immunity loci and corresponding parasite antigenicity loci, maintained by coevolution in pathosystems, is common and can persist for millions of years. Such polymorphisms and how they persist or break down are both fundamentally interesting and important for human health and agriculture. Examples include the major histocompatibility complex in vertebrates and the gene-for-gene (GFG) relationships in plants and their parasites. GFG systems are well-understood genetically and an important source of disease resistance for plant bree

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8

Schofield, Adrian Darcy. "Cellular interactions between host and parasite." Thesis, University of Edinburgh, 1987. http://hdl.handle.net/1842/14358.

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9

Halvarsson, Peter. "Host-Parasite Interactions in Natural Populations." Doctoral thesis, Uppsala, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-300023.

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Parasitism is one of the most common ways of living and it has arised in many taxa. Parasites feed and live inside or on their hosts resulting in both long and short term consequences for the host. This thesis is exploring the phenotypic and genotypic effects of animals living with parasitic infections. I have been studying three different parasite groups and their associated host species: the great snipe, a lekking freshwater wader bird that migrates between Africa and Northern Europe; the tree sparrow, a stationary passerine found close to human settlements and lastly the water vole, a large

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10

Schulte, Rebecca Daniela. "Evolution of host-parasite interactions : Experimental host-parasite coevolution of Caenorhabditis elegans and its microparasite Bacillus thuringiensis /." Tübingen, 2008. http://opac.nebis.ch/cgi-bin/showAbstract.pl?sys=000254311.

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11

Rethinavel, Natarajan [UNESP]. "Nonlinear dynamics of within-host parasite competition." Universidade Estadual Paulista (UNESP), 2013. http://hdl.handle.net/11449/108886.

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Made available in DSpace on 2014-08-27T14:36:43Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-05-29Bitstream added on 2014-08-27T15:57:07Z : No. of bitstreams: 1 000778127.pdf: 1378513 bytes, checksum: d1d6783639c75c24813a467c1ea25eae (MD5)<br>Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)<br>Nesta tese estudamos a biologia de populações de sistemas hospedeiro-parasita, com especial atenção para os efeitos produzidos por múltiplas infecções de diferentes parasitas numa dada população de hospedeiros. Tal situação se assemelha a múlpiplas espécies competindo por

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12

Kosciuch, Karl L. "Host-parasite interactions on an experimental landscape." Diss., Manhattan, Kan. : Kansas State University, 2006. http://hdl.handle.net/2097/186.

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13

Beadell, Jon Sumner. "Emerging infectious disease host and parasite perspectives /." College Park, Md. : University of Maryland, 2007. http://hdl.handle.net/1903/6744.

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Thesis (Ph. D.) -- University of Maryland, College Park, 2007.<br>Thesis research directed by: Biology. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.

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14

McCall, Laura-Isobel. "Parasite and host determinants of visceral leishmaniasis." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=116947.

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Leishmaniasis is a neglected tropical disease caused by Leishmania protozoa and transmitted by a sand fly vector. There are three main disease manifestations: self-healing but scarring cutaneous leishmaniasis, mucocutaneous leishmaniasis with destruction of the mucosal tissues in the nose, mouth and throat, and visceral leishmaniasis in which parasites disseminate to the bone marrow, liver and spleen, leading to high fever, hepatosplenomegaly, wasting, and death in the absence of treatment. Visceral leishmaniasis is the second most lethal tropical disease after malaria. A key question of le

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15

Gregory, Richard D. "Host-parasite interactions : population and community ecology." Thesis, University of Oxford, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.276582.

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16

Anderson, Laura Fay. "Malaria proteins implicated in host-parasite interactions." Thesis, University of Edinburgh, 2007. http://hdl.handle.net/1842/1965.

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The invasive and transmission stages of the malaria parasite Plasmodium falciparum express several proteins with domains implicated in host-parasite interactions, that are potential vaccine candidates or drug targets. The expression patterns of two proteins PfTRAMP (Plasmodium Related Apical Merozoite Protein) and PCRAGS (Plasmodium cysteine related antigen of gametocytes and schizonts), containing such putative domains, are examined and their potential roles in merozoite invasion and egress are discussed. PfTRAMP has a possible role in merozoite invasion. Transcription occurs in mature schizo

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17

Reverter, Miriam. "Host-parasite interactions of coral reef fish." Thesis, Paris, EPHE, 2016. http://www.theses.fr/2016EPHE3060/document.

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Les parasites sont une partie très importante des écosystèmes, néanmoins, dans certains cas tels que l’aquaculture ils causent des épidémies. Dans cette thèse j’ai étudié les interactions hôte-parasite chez les poissons coralliens, dans les milieux naturels et les milieux aquacoles. J’ai étudié l’arrangement des communautés de 13 espèces de monogènes de 34 espèces de poissons papillon dans l’Indo-Pacifique. Les résultats montrent qu’il existe un patron de distribution stable des espèces, ce qui, combiné avec les résultats de l’étude biogéographique, suggère que la spécificité parasitaire obser

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18

Rethinavel, Natarajan. "Nonlinear dynamics of within-host parasite competition /." São Paulo, 2013. http://hdl.handle.net/11449/108886.

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Orientador: Roberto André Kraenkel<br>Banca: Hilda Cerdeira<br>Banca: Fernando Fagundes Ferreira<br>Banca: Mario José de Oliveira<br>Banca: Stefanella Boatto<br>Resumo: Nesta tese estudamos a biologia de populações de sistemas hospedeiro-parasita, com especial atenção para os efeitos produzidos por múltiplas infecções de diferentes parasitas numa dada população de hospedeiros. Tal situação se assemelha a múlpiplas espécies competindo por um mesmo recurso. Com os parasitas competindo por hospedeiros, diversos resultados no nível populacional podem ocorrer. Se ambos parasitas não puderem infecta

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19

Nichol, Claire Patricia. "Host-parasite interactions of larval cestode infections." Thesis, University of Edinburgh, 1985. http://hdl.handle.net/1842/30579.

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20

Messick, Joanne B. "Ehrlichia risticii : host cells and parasite interactions /." The Ohio State University, 1992. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487841975358703.

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21

Cuco, Ana Patrícia Domingues. "Host-parasite interactions in environmental stress scenarios." Doctoral thesis, Universidade de Aveiro, 2017. http://hdl.handle.net/10773/22246.

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Doutoramento em Biologia<br>The overarching objective of this thesis was to explore ecologically relevant scenarios of contamination by agrochemical fungicides, in particular their interaction with disease (a ubiquitous and relevant natural stressor), using a host (Daphnia spp.) × parasite (Metschnikowia bicuspidata) system as an experimental model. Because parasites act as modulators of population dynamics and genetic diversity, interaction scenarios between disease and anthropogenic factors (namely pollution) are important to clarify. For this work, copper sulphate and tebuconazole we

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22

Coon, Courtney A. c. "Host-Parasite Interactions in an Invasive Songbird." Scholar Commons, 2014. https://scholarcommons.usf.edu/etd/5004.

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Introduced species are the greatest threat to biodiversity after habitat loss. Understanding the processes that permit organisms to become successful invaders may provide opportunities to prevent or limit their dispersal and establishment and thereby alleviate some of their harmful effects. The goal of my dissertation research has been to investigate whether invasive species have distinctive interactions with parasites, and some of the mechanisms that may underlie that variation. I used one of the world's most successful vertebrate invaders as a case study: the house sparrow (Passer domesticus

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23

Panagiotou, Aristeidis. "Single-cell transcriptomics of host-parasite interactions." Electronic Thesis or Diss., Université Paris Cité, 2024. http://www.theses.fr/2024UNIP5225.

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Apicomplexa est un phylum composé de parasites intracellulaires eucaryotes obligatoires à plusieurs stades de vie. Ces parasites doivent souvent infecter plus d'un hôte pour terminer leur cycle de vie et ont développé une multitude de mécanismes pour optimiser leur contagiosité, leur persistance et leur évasion du système immunitaire de l'hôte. Theileria annulata infecte les leucocytes des ruminants et est l'agent causal de la theilériose. Les cellules infectées développent un phénotype semblable à celui de la leucémie. Le parasite provoque la mort d'environ 1 million de bovins chaque année, m

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24

Rahn, Anna-Katrin [Verfasser]. "Ecological and host behavioural aspects of parasite dispersal in a simple and a complex host–parasite system / Anna-Katrin Rahn." Bonn : Universitäts- und Landesbibliothek Bonn, 2018. http://d-nb.info/1200019776/34.

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25

McCarthy, Helen Olga. "Adaptive variation in trematode parasite lifecycles : implications of 2-host and 3-host cycles for parasite reproductive strategies and transmission." Thesis, University of Ulster, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.342314.

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26

Mubarak, Jamil Salim. "The host-parasite relationship of schistosomes in mice." Thesis, Bangor University, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321389.

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27

Crosswaite, Matthew John. "Parasite distribution and specificity in anuran host complexes." Thesis, Queen Mary, University of London, 1994. http://qmro.qmul.ac.uk/xmlui/handle/123456789/26224.

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This study was based on the parasite fauna of three anuran systems. In two of the systems; the spadefoot toads, Scaphiopus bombifrons and S. multiplicatus and the fire and yellow-bellied toads, Bombina bombina and B.variegata, inter-species hybridisation occurs. In the third system an autopolyploid species complex involves the Gray treefrogs, Hyla chrysoscelis and H.versicolor. The status of the Scaphiopus hybrid zone in Arizona was re-assessed by cellulose-acetate gel electrophoresis. Genotypic frequencies were comparable to those previously documented, indicating that a region of 'balanced i

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28

Craig, Barbara Hutchison. "Parasite diversity in a free-living host population." Thesis, University of Edinburgh, 2005. http://hdl.handle.net/1842/14732.

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The isolated and un-managed Soay sheep population of Hirta, St. Kilda, which has been monitored intensively since 1985, is a model system for host-parasite studies. In hosts that died in the 2001/2 population crash, hitherto unknown and unexpected trends in the abundance of the main parasite species with host age were revealed. Specifically, previous studies in this system have failed to identify large <i>Trichostrongylus axei </i>and <i>T. vitrinus </i>burdens in the abomasum and small intestine respectively, which declined with host age, whereas <i>Teladorsagia circumcincta </i>burdens actua

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29

Gillingham, Emma. "The effect of climate on host-parasite interactions." Thesis, Cardiff University, 2015. http://orca.cf.ac.uk/84409/.

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Ecological systems are responding to changes in climate, and due to their ubiquitous nature, parasites will not be exempt from such changes. Understanding the effect that global climate change will have on parasites is of utmost importance, because there will be climate-driven implications for them and their hosts. This thesis addresses fundamental questions about the effect that a changing global climate will have on host-parasite interactions. First, a meta-analysis investigating general trends of parasites exposed to climatic perturbations found that warmer temperatures increased parasite a

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30

Masui, Hironori. "STUDIES ON HOST-PARASITE INTERACTIONS IN TARO TUBERS." Kyoto University, 1993. http://hdl.handle.net/2433/168920.

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本文データは平成22年度国立国会図書館の学位論文(博士)のデジタル化実施により作成された画像ファイルを基にpdf変換したものである<br>Kyoto University (京都大学)<br>0048<br>新制・論文博士<br>博士(農学)<br>乙第8374号<br>論農博第1864号<br>新制||農||666(附属図書館)<br>学位論文||H5||N2636(農学部図書室)<br>UT51-94-B227<br>(主査)教授鬼頭誠, 教授小清水弘一, 教授木村光<br>学位規則第4条第2項該当

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31

Li, Jia. "Metabonomic characterisation of host-parasite interactions in vivo." Thesis, Imperial College London, 2009. http://hdl.handle.net/10044/1/11805.

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32

Prior, Kimberley Faith. "The evolutionary ecology of circadian rhythms in malaria parasites." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/29562.

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Biological rhythms are thought to have evolved to enable organisms to organise their activities according to the Earth’s predictable cycles, but quantifying the fitness advantages of rhythms is challenging and data revealing their costs and benefits are scarce. More difficult still is explaining why parasites that exclusively live within the bodies of other organisms have biological rhythms. Rhythms exist in the development and traits of parasites, in host immune responses, and in disease susceptibility. This raises the possibility that timing matters for how hosts and parasites interact and,

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33

Ofong, Anthony Ukaobasi. "Rosellinia ring dying of Salix repens L. : host range; and host-parasite interactions." Thesis, University of Oxford, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.279992.

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34

Li, Dongmei. "Immune reactions involved in parasitoid-host interactions /." Title page, contents and abstract only, 2002. http://web4.library.adelaide.edu.au/theses/09PH/09phl6926.pdf.

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35

DEBOLT, JACK WARNER. "PARASITIZATION OF LYGUS LINEOLARIS (HEMIPTERA: MIRIDAE) BY LEIOPHRON UNIFORMIS (HYMENOPTERA: BRACONIDAE): HOST DEFENSE AND HOST ACCEPTANCE." Diss., The University of Arizona, 1987. http://hdl.handle.net/10150/184000.

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The ability of Leiophron uniformis (Gahan) to parasitize 4 Lygus spp. was determined. While L. uniformis readily attacked Lygus hesperus (Knight), L. lineolaris (Palisot de Beauvois), L. elisus Van Duzee, and L. desertinus Knight, only 6.7% of the L. lineolaris attacked were parasitized compared to 84-87% parasitization of the other species. Two factors were found to cause the low rate of parasitism of L. lineolaris. L. uniformis oviposited in (accepted) few of the L. lineolaris nymphs attacked and most eggs found were encapsulated by the host. Nymphs less than 48-hr old were readily parasitiz

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36

Méléard, Sylvie, and Sylvie Roelly. "A host-parasite multilevel interacting process and continuous approximations." Universität Potsdam, 2011. http://opus.kobv.de/ubp/volltexte/2011/5169/.

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We are interested in modeling some two-level population dynamics, resulting from the interplay of ecological interactions and phenotypic variation of individuals (or hosts) and the evolution of cells (or parasites) of two types living in these individuals. The ecological parameters of the individual dynamics depend on the number of cells of each type contained by the individual and the cell dynamics depends on the trait of the invaded individual. Our models are rooted in the microscopic description of a random (discrete) population of individuals characterized by one or several adaptive traits

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37

Kanatani, Sachie. "Host-parasite interactions in the dissemination of Toxoplasma gondii." Doctoral thesis, Stockholms universitet, Institutionen för molekylär biovetenskap, Wenner-Grens institut, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-148573.

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Toxoplasma gondii is an obligate intracellular parasite that infects virtually all warm-blooded organisms. Systemic dissemination of T. gondii in the organism can cause life-threatening infection that manifests as Toxoplasma encephalitis in immune-compromised patients. In addition, mounting evidence from epidemiological studies indicates a link between chronic Toxoplasma infection and mental disorders. To better understand the pathogenesis of toxoplasmosis, basic knowledge on the host-parasite interactions and the dissemination mechanisms are essential. Previous findings have established that,

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38

Otti, Oliver. "Host-parasite interactions : experimental studies on virulence and transmission." kostenfrei, 2007. http://e-collection.ethbib.ethz.ch/view/eth:29734.

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39

Keeling, Matthew James. "The ecology and evolution of spatial host-parasite systems." Thesis, University of Warwick, 1995. http://wrap.warwick.ac.uk/30/.

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All ecological and epidemiological systems are embedded in space and composed of individuals; these facts often have a profound effect on the dynamics and means many tools and definitions require reformulation. Modelling has always been about taking highly complex dynamical systems, such as the natural environment, and attempting to simplify them to a leve that can be conceptualised, in the process losing all the features that are not understood or not anticipated. The individual based spatial models which form the basis of this work start from the simple rules for individuals and build up to

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40

Allan, Fiona Elizabeth. "Host-parasite interactions : studies on schistosome diagnosis and transmission." Thesis, University of Leeds, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.550421.

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The trematode Schistosoma haematobium, which causes urinary schistosomiasis in humans, is endemic to Unguja island, Zanzibar and the freshwater snail Bulinus globosus acts as the intermediate host in this setting. Hence the distribution and infectivity of these snails are directly implicated in control of the disease within the human population. In this thesis, a variety of different experiments were undertaken to assess various aspects of the transmission process encompassing S. haematobium levels in snail populations, miracidial choice patterns and development of molecular tools for assessin

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41

Gharbawi, W. Y. A. "Host-parasite relationships of the common goby, Pomatoschistus microps." Thesis, Swansea University, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.637049.

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<i>Pomatoschistus microps</i> at Salthouse Point, Burry Inlet, Wales return to the estuary and spawn during June, the 1-group adults then disappear and presumably die but the developing juveniles become heavily parasitized with overdispersed, innocuous, encysted digenean metacercariae namely <i>Cryptocotyle jejuna</i> and <i>C.lingua</i> in subcutaneous muscle, <i>C.concava</i> (Heterophydae), in the body cavity, <i>Labratrema minimus</i> (Bucephalidae), in the liver, <i>Timoniella imbutiforme</i> and <i>T.praeterita</i> (Acanthostoidae) in subcutaneous muscle. Host weight, condition and other

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42

Pascua, Laura del Carmen Lopez. "Environmental and genetic determinants of host-parasite coevolutionary dynamics." Thesis, University of Oxford, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.531978.

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43

Bray, Daniel Peter. "Host-parasite interactions in the common shrew (Sorex araneus)." Thesis, University of Liverpool, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.408575.

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Barr, Kathryn J. "Aspects of the host-parasite relationships of Polymyxa betae." Thesis, University of East Anglia, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.334265.

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45

Dusi, Eike. "Experimental Host-Parasite Co-Evolution in a Changing Environment." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2016. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-199218.

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Parasites with exclusive vertical transmission from host parent to offspring are an evolutionary puzzle. Any fitness costs for infected hosts risk the selective elimination of these parasites because their fitness is linked to host reproduction. One of the main evolutionary transitions from parasitism towards beneficial or mutualistic associations may therefore encompass a change from horizontal transmission to vertical transmission. In this thesis, the experimental evolution study on Paramecium and Holospora supports this hypothesis. The parasite nearly entirely lost horizontal transmission c

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46

Prada, Jimenez de Cisneros Joaquin M. "Quantification of host-parasite interactions : sheep and their nematodes." Thesis, University of Glasgow, 2014. http://theses.gla.ac.uk/6156/.

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The objective of this dissertation is to use modelling and statistical approaches to expand our knowledge of the immune responses against gastrointestinal nematode infections, to assess the impact of nematode infection, and to use our improved knowledge to examine novel means of selective breeding in farm animals (sheep) as a control strategy. To expand the knowledge of the host immune response against infection, Chapter 2 of this dissertation focuses on immunoglobulin A (IgA), an antibody that binds nematode molecules, and its transfer through the body from the abomasal mucus (i.e. site of in

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47

Liesbeth, Martina Frias Villarroel. "Host -parasite community interactions in a human-modified habitat." Kyoto University, 2019. http://hdl.handle.net/2433/242654.

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付記する学位プログラム名: 霊長類学・ワイルドライフサイエンス・リーディング大学院<br>Kyoto University (京都大学)<br>0048<br>新制・課程博士<br>博士(理学)<br>甲第21616号<br>理博第4523号<br>新制||理||1649(附属図書館)<br>京都大学大学院理学研究科生物科学専攻<br>(主査)教授岡本宗裕, 准教授 Andrew MacIntosh, 教授髙井正成<br>学位規則第4条第1項該当

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48

Pritchard, J. "Host specificity in aphid parasitoids (Hymenoptera : Aphidiidae)." Thesis, Bucks New University, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.384680.

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49

White, Emily Claire. "Infection by the gastrointestinal parasite Trichuris muris : defining the microbiota of the parasite and the host." Thesis, University of Manchester, 2016. https://www.research.manchester.ac.uk/portal/en/theses/infection-by-the-gastrointestinal-parasite-trichuris-muris-defining-the-microbiota-of-the-parasite-and-the-host(e29ed75d-014d-4e36-87ed-a6db82845511).html.

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Intestinal dwelling parasites live in close association with the complex microbiota that inhabit our intestinal tracts. The intestinal helminth, Trichuris muris, depends on these bacteria for egg hatching and successful establishment of infection within the epithelium of the caecum and colon. Infection causes significant alterations to the host intestinal microbiota, including a decrease in bacterial diversity and shifts in proportions of certain bacterial groups. This is accompanied by a decrease in Foxp3+ regulatory T cells and changes to the metabolic potential of the host microbiota, conse

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Arnold, Markus F. F. "Host-pathogen interactions in chronic infections." Thesis, University of Aberdeen, 2012. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=192267.

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Abstract:

The BacA protein plays a key role in the symbiosis of Sinorhizobium meliloti with the leguminous plant alfalfa (Medicago sativa) and is proposed to be the transmembrane subunit of an ATP‐binding cassette (ABC) transporter. BacA homologues are also present in Brucella species, enteric bacteria (known as SbmA) and Mycobacterium tuberculosis. The S. meliloti‐alfalfa symbiosis, although beneficial to both partners, can also be viewed as a chronic infection. The M. tuberculosis BacA protein is important for M. tuberculosis for the maintenance of a chronic infection. In order to study the M. tubercu

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