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Dissertations / Theses on the topic 'HPLC method development'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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1

Wintergerst, Mieke. "Detection of inositol phosphates with HPLC-ICP-AES : Method development." Thesis, Uppsala universitet, Analytisk kemi, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-202003.

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Inositol phosphates (IPs) represent a major part of the organic phosphorus found in the environment, which makes their identification and quantification very important. The goal of this project was to explore the possibility of quantification of IPs with inductively coupled plasma - atomic emission spectrometry (ICP - AES). This paper deals with the creation of an in-house IP standard and the considerations for the successful linking of high performance liquid chromatography (HPLC) with ICP - AES. Experiments with different nebulizers, mobile phases, standard solutions and model substance were

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2

Pretorius, Marguerite. "PheroidTM-based anti-malarial formulations : HPLC method development and stability studies." Thesis, North-West University, 2008. http://hdl.handle.net/10394/4180.

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Malaria remains one on the world's most common infectious diseases with 300 to 500 million cases every year. The current treatment of malaria is restricted due to ever increasing drug resistance, cost of treatment and the availability of treatment. When looking at solutions for these problems, new drug delivery systems should be taken into consideration. The Pheroid™ drug delivery system which incorporates Pheroid™ technology can be placed in this category and the stability of anti-malarial drugs in combination with the Pheroid™ drug delivery system was investigated. The main objectives of thi

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3

Ganti, Satyakala. "DEVELOPMENT OF HPLC METHODS FOR PHARMACEUTICALLY RELEVANT MOLECULES; METHOD TRANSFER TO UPLC: COMPARING METHODS STATISTICALLY FOR EQUIVALENCE." Diss., Temple University Libraries, 2011. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/118587.

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Chemistry<br>Ph.D.<br>High Pressure Liquid Chromatography (HPLC) is a well-known and widely used analytical technique which is prevalent throughout the pharmaceutical industry as a research tool. Despite its prominence HPLC possesses some disadvantages, most notably slow analysis time and large consumption of organic solvents. Ultra Pressure Liquid Chromatography (UPLC) is a relatively new technique which offers the same separation capabilities of HPLC with the added benefits of reduced run time and lower solvent consumption. One of the key developments which facilitate the new UPLC technology

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4

Undin, Torgny. "Development and improvement of methods for characterization of HPLC stationary phases." Licentiate thesis, Uppsala universitet, Analytisk kemi, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-166978.

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High Performance Liquid Chromatography (HPLC) is a widely used tech-nique both for detecting and purifying substances in academy and in the industry. In order to facilitate the use of, and knowledge in HPLC, character-ization of stationary phases is of utmost importance. Tailor made characteri-zation methods and workflows are steadily increasing the speed and accura-cy in which new separation systems and methods are developed. In the field fundamental separation science and of preparative chromatography there is always the need for faster and more accurate methods of adsorption isotherm determ

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5

Andersson, Anja. "Method development for the determination of thiols using HPLC with fluorescence detection." Thesis, Umeå universitet, Kemiska institutionen, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-59827.

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6

Zhong, Fanyi. "DEVELOPMENT AND APPLICATIONS OF HPLC-MS/MS BASED METABOLOMICS." Miami University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=miami1524792637748877.

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7

Kühn, Antoinette. "Pro-Pheroid-based antiretroviral formulations : HPLC method development and stability studies / Antoinette Kühn." Thesis, North-West University, 2008. http://hdl.handle.net/10394/2320.

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8

Oteef, Mohammed Dhafer Y. "Analysis of the potato sprout inhibitor 1, 4-dimethylnapthalene : HPLC method development and applications." Thesis, University of Glasgow, 2008. http://theses.gla.ac.uk/319/.

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1,4-Dimethylnaphthalene (1,4-DMN) is a pesticide used for inhibiting the sprouting of stored potatoes, and therefore prolonging the storage time. It is registered for commercial use in different parts of the world (e.g. USA and New Zealand) and its registration process in the EU is at an advanced stage. Limited information is available regarding the behaviour and fate of this pesticide in the environment, and therefore, various studies are required in this field. In such studies, analytical methods for the determination of 1,4-DMN in the different environmental samples are a core element. This

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9

Schmidt, Alexander H. [Verfasser]. "Innovative HPLC Method Design (Development & Understanding) within the Pharmaceutical Lifecycle / Alexander H. Schmidt." Berlin : Freie Universität Berlin, 2018. http://d-nb.info/1150238100/34.

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10

Lindholm, Johan. "Development and Validation of HPLC Methods for Analytical and Preparative Purposes." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis, Univ.-bibl. [distributör], 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4442.

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11

Wang, Yu. "HPLC method development for the evaluation of pheromones from the dwarf African clawed frog Hymenochirus." Scholarly Commons, 2003. https://scholarlycommons.pacific.edu/uop_etds/587.

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12

Juaristi, Ane Iruretagoiena. "HPLC-FL for determination of hormones in bivalves." Master's thesis, Universidade de Aveiro, 2014. http://hdl.handle.net/10773/14301.

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Mestrado em Química - Química Analítica e Qualidade<br>The main objective of this work was the application of an isocratic high performance liquid chromatography (HPLC) method coupled with a fluorescence detector to find the best conditions for the separation and quantification of 17β-estradiol (E2) and 17α-ethinyl estradiol (EE2) hormones in bivalve samples. A reversed phase column (Kromasil 100 C18, 5μm, 15 x 0.21cm), was employed with a fluorescence detector operating at excitation and emission wavelengths of 280nm and 305nm, respectively. A calibration curve was obtained with a good correl

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13

Van, den Berg Elaine. "Development of a stability indicating HPLC method for the Pheroid™ delivery system / Elaine van den Berg." Thesis, North-West University, 2010. http://hdl.handle.net/10394/5105.

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Stability plays an important role in the development of a new drug product. High Performance Liquid Chromatography (HPLC) is considered a stability indicating method of analysis. It is widely used in the pharmaceutical industry for the quantification of small organic molecules during stability testing. Previous stability studies conducted on Pheroid™-based drug products, experienced problems with the generation of reliable data by means of HPLC analysis. With these studies it was concluded that the inconclusive results could either be attributed to the stability of the delivery system itself a

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14

Wang, Yu. "HPLC method development for the evaluation of pheromones from the dwarf African clawed frog Hymenochirus : a thesis." Scholarly Commons, 2001. https://scholarlycommons.pacific.edu/uop_etds/587.

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15

Tu, Travis Y. "HPLC and MS/MS Method for the Separation and Identification of Inositol Phosphates in C. Reinhardtii." Scholarship @ Claremont, 2016. http://scholarship.claremont.edu/cmc_theses/1306.

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Inositol phosphates (IPs) have important cellular functions from teleomere maintenance (IP7 and IP8) to Ca2+ signaling pathways (1, 4, 5-IP3). Yet there is no robust, quantitative method to separate all the inositol phosphate isomers from IP1 to IP8. Four findings contributed heavily towards the development of a robust, quantitative IP isomer separation and identification method on the EskpertTM MicroLC 200+ QTrap 6500 system with a SelexIonTM DMS attachment. 1) TCA from inositol phosphate algal extractions was removed by elution with 100 mM ammonium carbonate, ammonium formate, or ammonium bi

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16

Elmroth, Edvin. "Method development for quality control of the primary explosive, Potassium 4,6-Dinitrobenzofuroxan (KDNBF)." Thesis, Örebro universitet, Institutionen för naturvetenskap och teknik, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-84289.

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“Green” explosives are an important sub-family of explosives due to the banning of explosives based on heavy metals, such as lead azide and lead styphnate, according to the REACH list. A substitute to lead azide is potassium 4,6-dinitrobenzofuroxane (KDNBF) which is an alternative “green” explosive. Hence there is an upcoming need for analytical and quality control protocols for KDNBF. In this report is HPLC-UV/VIS, GC-FID and potentiometric titration evaluated for their suitability as methods for testing of KDNBF. The results implies that KDNBF can be analyzed by GC-FID, when dissolved in DMS

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17

Beelders, Theresa. "HPLC method development for the characterisation of the flavonoid and phenolic acid composition of rooibos (Aspalathus linearis) infusions." Stellenbosch : Stellenbosch University, 2011. http://hdl.handle.net/10019.1/17818.

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Thesis (MSc Food Sc)--Stellenbosch University, 2011.<br>ENGLISH ABSTRACT: Rooibos tea, produced from the endemic South African fynbos plant Aspalathus linearis, has various healthpromoting benefits which can largely be attributed to its phenolic composition. In this study, the reversedphase liquid chromatographic (RP-LC) separation of the principal phenolic constituents of aqueous rooibos infusions was optimised on conventional high-performance liquid chromatography (HPLC) instrumentation. The phenolic constituents comprised dihydrochalcones (aspalathin and nothofagin), flavones (orientin,

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18

McBride, M. B. "The development and evaluation of an HPLC method of analysis for nicotine and its major metabolites in urine." Thesis, University of Bristol, 1988. http://hdl.handle.net/1983/9268fc8e-2d95-426e-b6a3-7cdfd849fc15.

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This dissertation details the development and evaluation of an HPLC method of analysis for nicotine and the metabolites cotinine, nicotine-1'-N-oxide and 3' hydroxycotinine in urine samples. The significance of nicotine, its absorption, metabolism and excretion in man and other animals have been described in Chapter 1. Chapter 2 deals with the development of the HPLC method of analysis using both isocratic and gradient elution with W detection. A selection of packing materials/mobile phases covering different retention mechanisms was investigated. A separation of nicotine, cotinine, nicotine-

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19

Amann, Laura. "Development and Validation of an Analytical Method for Phenolic Acid Extraction from Cereals and Quantification using HPLC-UV." Thesis, Linnéuniversitetet, Institutionen för kemi och biomedicin (KOB), 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-77227.

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Cereals are rich in phenolic acids, a group of secondary plant metabolites that are associated with reduced risk of chronic diseases. The objective was to develop and internally validate a method for extraction and quantification of phenolic acids in cereals using HPLC-UV and to apply this method for quantification of the content of phenolic acids in several species of Swedish cereals. Different procedures for extraction of phenolic acids from cereal grains using acid or base hydrolysis with and without subsequent enzymatic treatment were tested. Both the extraction procedure and the chromatog

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20

LA, MAIDA NUNZIA. "Development and validation of analytical methods with hyphenated chromatographic techniques for the determination of NPS and drugs of abuse in biological matrices." Doctoral thesis, Università Politecnica delle Marche, 2022. https://hdl.handle.net/11566/299808.

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Sin dal 1990 l'apparizione sul mercato di nuove sostanze psicoattive (NPS) è un fenomeno mondiale sempre crescente. Ogni anno vengono introdotte nuove sostanze nel mercato della droga come alternative legali alle sostanze controllate dalla legge. L’identificazione di queste nuove sostanze in matrici biologiche rappresenta una continua sfida per i laboratori di analisi. È estremamente importante sviluppare metodologie analitiche in grado di identificare sostanze sconosciute consentendone il monitoraggio e fornendo informazioni scientifiche riguardo la farmacocinetica, possibili range di tossici

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21

Keenan, Helen Elizabeth. "The development of a SPE-HPLC method of analysis to assess the environmental fate of natural and synthetic oestrogens." Thesis, University of Strathclyde, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.367077.

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22

Hillberg, Paulina. "Development of a quantitative chromatographic method for the determination of Imatinib and its main metabolite in human plasma." Thesis, Linköping University, Department of Physics, Chemistry and Biology, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-56627.

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<p>The objective of this master thesis was to develop an analytical method for the quantification of the cancer drug Imatinib and its main metabolite CGP74588 in plasma. Imatinib is used in the treatment of chronic myeloid leukemia and gastrointestinal stroma tumors. A quantitative analytical method was developed where reversed-phase columns with different stationary phases were studied and the sensitivity was tested with both UV detectors and a mass spectrometric detection. Since the substances were measured in plasma a solid-phase extraction was developed to purify the samples before analysi

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23

Troalen, Lore Gertrud. "Historic dye analysis : method development and new applications in cultural heritage." Thesis, University of Edinburgh, 2013. http://hdl.handle.net/1842/11717.

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A review of the main natural dyes (particularly yellow flavonoids and red anthraquinones) and proteinaceous substrates used in Historical Tapestries and North American porcupine quill work was undertaken, and is summarised in Chapter 1. The analysis of natural dyes which have been used on museum artefacts other than textiles has received little systematic study, particularly those of non-European origin. In this research, the use of Ultra Performance Liquid Chromatography (UPLC) for study of natural dyes found on historical textiles and ethnographical objects decorated with porcupine quill wor

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24

Aras, Ebru. "Characterization Of Skeletal Muscle Lipids In Obese Mice Lines." Master's thesis, METU, 2012. http://etd.lib.metu.edu.tr/upload/12614568/index.pdf.

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Obesity becomes an epidemic health problem in developing and developed countries, which arises due to stable life style and increase in the consumption of high fat diets. Obesity is generally accompanied with various clinical disorders, such as insulin resistance, type II diabetes, hypertension, dyslipidemia and cardiovascular diseases. This study aims to characterize and quantify different lipid classes in longissimus dorsi (LD) and quadriceps (Q) skeletal muscles of control (DBA/2J), obese Berlin fat mouse inbred (BFMI) and Berlin muscle mouse inbred (BMMI) lines, which display high fat and

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25

Mamunooru, Manasa. "DEVELOPMENT OF NOVEL METHODS FOR THE RAPID SEPARATION OF BIOMOLECULES." Diss., Temple University Libraries, 2013. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/214806.

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Chemistry<br>Ph.D.<br>Successful methods for the separation of biomolecules like amino acids, proteins, peptides, and DNA have been developed previously using HPLC, GC, GC-MS, and CE. Recently CE has become a routine laboratory technique in the analysis of biological molecules. Even though high-resolution separations with small sample volumes is the main advantage, CE is limited by lower sensitivity detection of analytes when universal detectors like UV absorption or refractive index detectors are used. Therefore, sensitivity enhancement can be obtained by either using different detection sche

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26

Nou, Tepneth, University of Western Sydney, of Science Technology and Environment College, and of Science Food and Horticulture School. "Development of an analytical method for the analysis of Quizalofop-p-ethyl and its metabolite Quizalofop acid in soybean by HPLC." THESIS_CSTE_SFH_Nou_T.xml, 2002. http://handle.uws.edu.au:8081/1959.7/606.

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Quizalofop-p-ethyl is a herbicide introduced in the mid 1980's with apparent low toxicity and is readily degradable.Quizalofop-p-ethyl is a member of the aryloxyphenoxypropionate group of herbicides and is a postemergence herbicide used for pulses (including soybean) and vegetables. The aim of the project discussed in this study is to develop an analytical method for the sensitive and reliable determination of quizalofop-p-ethyl and quizalofop acid in soybean using HPLC. Soybean is chosen as a typical agricultural crop. It has 15 to 20 percent oil content and is a crop which has been successfu

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Nou, Tepneth. "Development of an analytical method for the analysis of Quizalofop-p-ethyl and its metabolite Quizalofop acid in soybean by HPLC." Thesis, View thesis View thesis, 2002. http://handle.uws.edu.au:8081/1959.7/606.

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Quizalofop-p-ethyl is a herbicide introduced in the mid 1980's with apparent low toxicity and is readily degradable.Quizalofop-p-ethyl is a member of the aryloxyphenoxypropionate group of herbicides and is a postemergence herbicide used for pulses (including soybean) and vegetables. The aim of the project discussed in this study is to develop an analytical method for the sensitive and reliable determination of quizalofop-p-ethyl and quizalofop acid in soybean using HPLC. Soybean is chosen as a typical agricultural crop. It has 15 to 20 percent oil content and is a crop which has been successfu

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Nou, Tepneth. "Development of an analytical method for the analysis of Quizalofop-p-ethyl and its metabolite Quizalofop acid in soybean by HPLC /." View thesis View thesis, 2002. http://library.uws.edu.au/adt-NUWS/public/adt-NUWS20030401.172911/index.html.

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Thesis (Ph.D.) -- University of Western Sydney, [2002].<br>"A thesis presented to the University of Western Sydney in partial fulfillment of the requirements for the degree of Doctor of Philosophy " Includes references and appendices.

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29

Jones, Jennifer Ruth Miller. "Development of a complementary chemiluminescence/HPLC method for predicting the chemical fate of 1-Bromo-3-Chloro-5,5-Dimethylhydantoin under aqueous conditions /." Electronic version (PDF), 2003. http://dl.uncw.edu/etd/2003/jonesj/jenniferjones.html.

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30

Pickering, M., and Stacy D. Brown. "Development and Validation of a High-Performance Liquid Chromatography with Ultraviolet Detection (HPLC-UV) Method for the Quantification of Ertapenem in Human Plasma." Digital Commons @ East Tennessee State University, 2011. https://dc.etsu.edu/etsu-works/5290.

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31

Mills, Heidi Clare Maria. "Development of a Method of Analysis by High Performance Liquid Chromatography for Products of the Nitric Acid Oxidation of D-Glucose." The University of Waikato, 2007. http://hdl.handle.net/10289/2517.

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This thesis explored the development of a faster and more efficient means of qualitative and quantitative analysis of the products of the nitric acid oxidation of D-glucose and other simple sugars, for the Shafizadeh Rocky Mountain Center for Wood and Carbohydrate Chemistry. During the research, analysis was carried out based on previous work completed in a similar area using two Aminex HPX-87H+ cation-exchange columns at different temperatures, and plumbed in series. Standards were filtered and injected on to the columns, then eluted with 5 mM sulfuric acid. A total run time of 33 minutes

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Schulze, Alexandra Elizabeth. "HPLC method development for characterisation of the phenolic composition of Cyclopia subternata and C. maculata extracts and chromatographic fingerprint analysis for quality control." Thesis, Stellenbosch : Stellenbosch University, 2013. http://hdl.handle.net/10019.1/85773.

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Thesis (MScFoodSc)--Stellenbosch University, 2013.<br>ENGLISH ABSTRACT: The phenolic composition of Cyclopia species is believed to be partially responsible for the numerous health promoting properties associated with their extracts. Current quality control measures do not accommodate variation in phenolic profiles of Cyclopia species. In this study, comprehensive high performance liquid chromatography (HPLC) methods were developed for the improved characterisation of the phenolic composition of aqueous extracts of two Cyclopia species (C. subternata and C. maculata). The methods were deve

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33

Lemasson, Elise. "Stratégies chromatographiques en phase liquide et supercritique pour l'analyse de candidats médicaments." Thesis, Orléans, 2018. http://www.theses.fr/2018ORLE2005/document.

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Le profilage d’impuretés de candidats médicaments est une préoccupation majeure des industries pharmaceutiques. L’identification et la quantification des impuretés doivent être strictement contrôlées pour assurer l’efficacité et la toxicité limitée du principe actif. Il est donc nécessaire de disposer de méthodes analytiques performantes afin de s’assurer que l’ensemble des impuretés est identifié. L’HPLC phase inverse sur phase C18 reste aujourd’hui la méthode de choix pour cette tâche. Cependant, il arrive que cette méthode échoue, notamment lorsque le principe actif n’est pas suffisamment r

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34

Durner, Bernhard [Verfasser], Frank-Michael [Akademischer Betreuer] Matysik, and Christian [Akademischer Betreuer] Neusüss. "Analyzing the chemical heterogeneity of poly(dimethylsiloxanes) and other polymers: Development and optimization of a polymer HPLC method / Bernhard Durner ; Frank-Michael Matysik, Christian Neusüss." Regensburg : Universitätsbibliothek Regensburg, 2020. http://d-nb.info/121670354X/34.

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SOUZA, JEFFERSON RODRIGUES DE. "METHOD DEVELOPMENT FOR THE DETERMINATION OF TOTAL SE BY ICP-MS AND ITS SPECIES BY HPLC-ICP-MS IN FOOD SUPPLEMENT AND IN ISOTOPICALLY ENRICHED YEAST." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2017. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=33733@1.

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PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO<br>COORDENAÇÃO DE APERFEIÇOAMENTO DO PESSOAL DE ENSINO SUPERIOR<br>PROGRAMA DE SUPORTE À PÓS-GRADUAÇÃO DE INSTS. DE ENSINO<br>O consumo de suplementos alimentares tem apresentado um aumento significativo nos últimos anos principalmente pelo grande apelo desse produto em relação a complementação da dieta com elementos essenciais e a melhora e manutenção da saúde. A combinação do crescente consumo e o livre acesso a esse produto, aliado a ausência de fiscalização por parte dos órgãos governamentais torna seu consumo descontrolado, um potencial r

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36

Onuoha, Mary Remigius Agatha Verfasser], and Ekkehard [Akademischer Betreuer] [Haen. "Therapeutic Drug Monitoring of Antipsychotics - HPLC Analytical Method Development and Pharmaceutical Advices to the Ward Clinicians - For Successful Individualized Therapy / Mary Remigius Agatha Onuoha ; Betreuer: Ekkehard Haen." Regensburg : Universitätsbibliothek Regensburg, 2016. http://d-nb.info/1121302726/34.

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Onuoha, Mary Remigius Agatha [Verfasser], and Ekkehard [Akademischer Betreuer] Haen. "Therapeutic Drug Monitoring of Antipsychotics - HPLC Analytical Method Development and Pharmaceutical Advices to the Ward Clinicians - For Successful Individualized Therapy / Mary Remigius Agatha Onuoha ; Betreuer: Ekkehard Haen." Regensburg : Universitätsbibliothek Regensburg, 2016. http://d-nb.info/1121302726/34.

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Monteiro, Sérgio Henrique. "Desenvolvimento e validação de metodologia para determinação de resíduos de pesticidas piretróides por HPLC em feijão." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/46/46133/tde-22062016-160326/.

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Um método rápido utilizando cromatografia liquida (LC) foi desenvolvido para determinação simultânea de 7 pesticidas piretróides (bifentrina, cipermetrina, fenpropatrina, fenvalerato, permetrina, lambda-cialotrina, e deltametrina). Os resíduos são extraídos com acetona e a partição realizada de acordo com o método multi-resíduos DFG-S19, substituindo diclorometano por acetato de etila/ciclohexano (1+1) e purificação usando cromatografia de permeação a gel com uma coluna Biobeads SX3 e acetato de etila/ciclohexano (1+1) como eluente. A separação por LC é realizada com uma coluna LiChrospher 100

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Goetz, Hilary Jane. "Development and application of an HPLC-MS/MS method for the characterization and quantification of a-retinyl esters and vitamin A in human plasma after consumption of a-carotene." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1408551701.

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Ram, Vijay [Verfasser], Hitendra S. [Verfasser] Joshi, and Paras P. Vekariya Rajesh [Verfasser] Ram. "Development and validation of HPLC method for simultaneous quantitative determination of Azilsartan medoxomil potassium and Chlorthalidone in human plasma / Vijay Ram, Hitendra S. Joshi, Paras P. Vekariya Rajesh Ram." München : GRIN Verlag, 2014. http://d-nb.info/1184031495/34.

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Ram, Vijay [Verfasser], Hitendra S. [Verfasser] Joshi, and Paras P. Vekariya Rajesh [Verfasser] Ram. "Development and validation of HPLC method for simultaneous quantitative determination of Azilsartan medoxomil potassium and Chlorthalidone in human plasma / Vijay Ram, Hitendra S. Joshi, Paras P. Vekariya Rajesh Ram." Munich : GRIN Verlag, 2015. http://d-nb.info/1097478874/34.

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Murphy, Kellyann M. "Analysis of Biodiesel Quality Using Reversed Phase High-Performance Liquid Chromatography." Scholarship @ Claremont, 2012. http://scholarship.claremont.edu/pomona_theses/45.

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The alternative fuel biodiesel is produced from the transesterification of vegetable oils or animal fat to fatty acid methyl esters. Pomona has a reactor on campus that can be used to run this reaction and produce biodiesel. The use of biodiesel has been found to lower air pollutant and greenhouse gas emissions, but can be potentially harmful to the engines if it contains impurities. This paper proposes a method using high-performance liquid chromatography to test the quality of biodiesel. This method utilizes instrumentation and materials that are available in Pomona College's Chemistry Depar

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Henriksson, Emma, and Martin Holm. "Kvantitativ analys av organiska syror i kylvätska." Thesis, Högskolan i Borås, Akademin för textil, teknik och ekonomi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:hb:diva-13499.

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Volvo Cars är ett välkänt företag som säljer bilar över hela världen. Idag skickar Volvo Cars sin kylvätska till leverantörer för analys. Processen är komplicerad och tar mycket tid. Det finns ett intresse hos Volvo Cars att själva kunna analysera kylvätskan. För att kunna göra detta krävs det att en metod som de kan använda för att analysera kylvätskan utvecklas. Examensarbetet syftar till att utveckla en metod som gör det möjligt att analysera koncentrationen av organiska syror i Volvos kylvätska. Analysen ska göras med hjälp av en High Performance Liquid Chromatography - HPLC. De organiska

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44

Brown, Jenelle Daria. "Development of a method for the simultaneous detection of mycotoxins in corn using supercritical fluid extraction (SFE), high performance liquid chromatography (HPLC), and electrospray-atmospheric pressure ionization/mass spectrometry (ES-API/MS) for extraction, separation, and identification." Thesis, University of Iowa, 1999. https://ir.uiowa.edu/etd/2802.

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Ammar, Amal [Verfasser]. "Analysis of drug substances by using new concepts of HPLC and development of some HPTLC methods / Amal Ammar." Berlin : Freie Universität Berlin, 2009. http://d-nb.info/1023956632/34.

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Raj, P. Mohan. "UV and HPLC methods development and validation of anti-retroviral drugs." Thesis, University of North Bengal, 2009. http://hdl.handle.net/123456789/1432.

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McCulloch, Melissa. "Development of Quantitative Bioanalytical Methods for the Measurement of Pharmaceutical Compounds via HPLC-UV and HPLC-MS/MS." Cleveland State University / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=csu1255046678.

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Pingeon, Marine. "Development and validation of analytical methods for therapeutic drug monitoring." Doctoral thesis, Universita degli studi di Salerno, 2019. http://elea.unisa.it:8080/xmlui/handle/10556/4509.

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2017 - 2018<br>The U.S. Food and Drug Administration defines as Precision or Personalized Medicine (PM) an innovative therapeutic approach that tailors therapy and prevention on patients based on inter-individual variabilities in molecular or environmental features and in lifestyles. The major goals of PM are to maximize treatment efficacy and to reduce cost, toxicities and therapy failure rates by early identification of patients who might benefit or not of a specific treatment. In this scenario, therapeutic drug monitoring (TDM) is an important laboratory tool for PM because of the poss

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Wilson, Michael Andrew. "Analysis of complex distributions of bacteriochlorophylls : development and application of HPLC and LC-MS methods." Thesis, University of York, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.422530.

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Latreche, Linda. "Development of HPLC/UV and HPLC/MS analytical methods for FR-900098 : a novel antimalarial compound experimental pharmacokinetic studies on rat and micro-pig." Strasbourg, 2009. http://www.theses.fr/2009STRA6239.

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FR-900098, un dérivé proche de la fosmydomicine, inhibite la croissance du parasite Plasmodium falciparum de manière deux fois plus efficace. Une méthode analytique basée sur la chromatographie ionique a été développée en vue de la détermination des paramètres pharmacocinétiques de FR-900098 dans le plasma humain, le plasma de rat, de micro-porc et dans la matrice d'urine de rat. La séparation de FR-900098 s'est faite sur une colonne AS11-HC (250 mm x 2 mm, Dionex), avec un temps de rétention tr =12. 25 min ± 0. 2 min et une détection UV à 230 nm. La phase mobile a consisté en une solution d'h

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