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Relevant bibliographies by topics / Hydrazide-Hydrazone

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Academic literature on the topic 'Hydrazide-Hydrazone'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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Journal articles on the topic "Hydrazide-Hydrazone"

1

Shalini, Agarwal, and Goyal Anju. "Exploring the Therapeutic Potential of Hydrazide-Hydrazone Derivatives: A Comprehensive Review." Pharmaceutical and Chemical Journal 7, no. 3 (2020): 100–107. https://doi.org/10.5281/zenodo.13954554.

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The exploration of novel compounds with antibacterial, anticancer, and anticonvulsant activities is a significant area of research due to the rising challenges posed by drug-resistant bacterial strains, cancer, and neurological disorders. The continual rise of drug-resistant bacterial strains, the complex challenges associated with cancer, and the persistent enigma of neurological disorders have fueled an ongoing quest for innovative therapeutic agents. Among the myriad compounds under investigation, hydrazide-hydrazone derivatives have emerged as promising candidates with diverse biological a

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Prateeptongkum, Saisuree, Nongnaphat Duangdee, and Wiratchanee Mahavorasirikul. "Evaluation of Cytotoxicity and Apoptosis Induced by Coumarin Hydrazide-Hydrazone Derivatives in Human Hepatocellular Carcinoma Cell Line." Trends in Sciences 21, no. 7 (2024): 7628. http://dx.doi.org/10.48048/tis.2024.7628.

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Coumarin and aryl hydrazide-hydrazone have attracted our attention due to their vast biological properties. Previous studies suggested that coumarin-tethered aryl hydrazide-hydrazone showed potent activities against HepG2. In the present study, we investigated the cytotoxic potency of the coumarin derivatives 1 - 3 to compare with coumarin hydrazine-hydrazone hybrids 4 and 5 against hepatocellular carcinoma HepG2 and LH86 cell lines. Among the tested coumarins, hybrids 4 and 5 showed highly potent activity against HepG2 with IC50 values of 17.82 ± 2.79 and 7.87 ± 0.88 𝜇g/mL, respectively. The

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Fatullayeva, P. A. "COMPLEXES OF METALS WITH HYDRAZONE HYDRAZIDE SALICYLIC ACID." Chemical Problems 19, no. 2 (2021): 79–83. http://dx.doi.org/10.32737/2221-8688-2021-2-79-83.

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Complexes of Cu (II), Ni (II), and Co (II) with hydrazone derivatives of salicylic acid hydrazide and 3,5-di-tert-butyl salicylic aldehyde (LH) were synthesized and the structure of these compounds studied by means of elemental analysis methods, IR and electronic spectroscopy, magnetochemistry and thermal analysis. It revealed that the complexes are monomeric and have a composition [MLXSoI] where M is a metal ion, L is a ligand, X is an inorganic anion, and Sol is a solvent molecule. LH- in the complexes behaves like a monoanionic tridentate ligand. It found that the resulting complexes exhibi

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Mateev, Emilio, Muhammed Tilahun Muhammed, Ali Irfan, Shubham Sharma, Maya Georgieva, and Alexander Zlatkov. "Hydrazide-hydrazones as novel antioxidants - in vitro, molecular docking and DFT studies." Pharmacia 71 (October 16, 2024): 1–8. http://dx.doi.org/10.3897/pharmacia.71.e133114.

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The pathogenesis of many diseases, such as obesity, depression, cancer, cataract, and neurodegenerative diseases, is related to the generation of reactive oxygen species (ROS). Structures possessing radical-scavenging properties act as antioxidants and they could prevent the progression of the aforementioned diseases. Therefore, the current work was focused on the resynthesis and the antioxidant evaluation of 13 hydrazide-hydrazones. Two in vitro tests - DPPH and ABTS, were applied for the determination of the antioxidant capacities. The free-radical scavenging assays displayed that the hydraz

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Mateev, Emilio, Muhammed Muhammed Tilahun, Ali Irfan, Shubham Sharma, Maya Georgieva, and Alexander Zlatkov. "Hydrazide-hydrazones as novel antioxidants - in vitro, molecular docking and DFT studies." Pharmacia 71 (October 16, 2024): 1–8. https://doi.org/10.3897/pharmacia.71.e133114.

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The pathogenesis of many diseases, such as obesity, depression, cancer, cataract, and neurodegenerative diseases, is related to the generation of reactive oxygen species (ROS). Structures possessing radical-scavenging properties act as antioxidants and they could prevent the progression of the aforementioned diseases. Therefore, the current work was focused on the resynthesis and the antioxidant evaluation of 13 hydrazide-hydrazones. Two <i>in vitro</i> tests - DPPH and ABTS, were applied for the determination of the antioxidant capacities. The free-radical scavenging assays displayed that the

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6

Shaji, Neethu, Sandhya M J Nair, and Shaiju S Dharan. "Coumarin Hydrazide: Chemistry, Synthesis and Pharmacological Activities - A Review." International Journal of Research and Review 9, no. 12 (2022): 16–26. http://dx.doi.org/10.52403/ijrr.20221202.

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Coumarins are heterocyclic compound with a benzopyrone structure. Coumarins are a large group of organic compounds found in several plants even in bacteria and fungi. The biological activities of coumarins and its derivatives includes anticoagulant, anticancer, antiulcer, antifungal, anti-HIV, antimicrobial, antiosteoporosis, antioxidant and anti- inflammatory activity. Hydrazide-hydrazone derivatives act as structural sub units in many pharmacologically active compounds including coumarins to give biological activities like antimicrobial, anticancer, antifungal, anti-inflammatory, antiviral,

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7

Wu, Jiale, Jiafeng Wang, Yinglong Han, Yu Lin, Jing Wang, and Ming Bu. "Synthesis and Cytotoxic Activity of Novel Betulin Derivatives Containing Hydrazide-Hydrazone Moieties." Natural Product Communications 16, no. 10 (2021): 1934578X2110553. http://dx.doi.org/10.1177/1934578x211055345.

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A series of novel betulin derivatives containing hydrazide-hydrazone moieties were synthesized. All compounds were evaluated for their cytotoxicity against four human carcinoma cell lines (HepG2, A549, MCF-7 and HCT-116) and a normal human gastric epithelial cell line (GES-1). Among them, compound 6i was the most potent against HepG2 and MCF-7 cell lines, with IC50 values of 9.27 and 8.87 μM, respectively. The results suggest that the incorporation of a hydrazide-hydrazone side chain at the C-28 position of betulin is beneficial for compounds to display significant cytotoxicity. Compound 6i ma

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8

Gera, Ankur, Chander Mohan, and Sandeep Arora. "Synthesis of Phthaloylglycyl Hydrazide Derivatives: Selective Protection of Phthalimide Group from Hydrazinolysis." Current Organic Synthesis 15, no. 6 (2018): 839–45. http://dx.doi.org/10.2174/1570179415666180601083256.

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Background: N-phthalimide amino acid hydrazide is a class of compounds that have the potential therapeutic use. In general, hydrazinolysis of N-substituted amino acid(s) ester removes the ester group and yields the corresponding hydrazide. However, in case if N-substitution group is phthalimide, phthalimide group is cleaved and not the ester group. The resulted compound, therefore, is amino acid ester rather than Nphthalimide amino acid hydrazide. The above class of compounds, because of susceptibility of phthalimide group to hydrazinolysis, has previously been synthesized by a lengthy three-s

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Abd El-Salam, N. M., Z. Y. Al Shoaibi, and G. A. Ahmed. "Chemical Studies on 3,6-Dichloropyridazine (Part 2)." E-Journal of Chemistry 8, no. 4 (2011): 1944–50. http://dx.doi.org/10.1155/2011/612825.

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3,6-Dichloropyridazine (1) reacted with 2-aminophenol, phenylalanine, acetophenone hydrazone derivatives, acid hydrazide derivatives and amino-aromatic acids (anthranilic acid and 5-bromoanthranilic acid) and yield the compounds (2), (3), (4a,b), (5a,b) and (6a,b) respectively. Reaction of compounds (5a,b) with acid hydrazide gave (8a,b). Also, compounds (6a,b) reacted with aromatic amino acid and gave (7a-c).

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GOKLANI, POONAM, and ANIL GUPTA. "Synthesis, Structural Characterization and Study of Biological Activity of Hydrazine Derivatives." Material Science Research India 14, no. 2 (2017): 190–93. http://dx.doi.org/10.13005/msri/140217.

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Hydrazide-hydrazone derivatives play vital role in development of various pharmacological activities such as anti-tubercular, antiproliferative and antitumor activities. Some novel biologically active Hydrazide derivatives substituted with heterocyclic moiety have been synthesized. All the synthesized compounds structures were confirmed by IR, NMR and Mass spectra. Synthesized compounds were subjected to antibacterial screening in vitro and biological activity in vivo.

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Book chapters on the topic "Hydrazide-Hydrazone"

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of oxovanadium(IV) complex with hydrazone of isonicotinic acid hydrazide." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 5. Springer Berlin Heidelberg, 2022. http://dx.doi.org/10.1007/978-3-662-65098-1_7.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of chromium(III) complex with hydrazone of isonicotinic acid hydrazide." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 5. Springer Berlin Heidelberg, 2022. http://dx.doi.org/10.1007/978-3-662-65098-1_31.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of manganese(III) complex with hydrazone of isonicotinic acid hydrazide." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 5. Springer Berlin Heidelberg, 2022. http://dx.doi.org/10.1007/978-3-662-65098-1_79.

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Pardasani, R. T., and P. Pardasani. "Molar magnetic moment of oxovanadium(IV) derivative with bis(hydrazone) derived from 1,1′-diacetylferrocene and isonicotinic acid hydrazide." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 1. Springer Berlin Heidelberg, 2021. http://dx.doi.org/10.1007/978-3-662-62478-4_41.

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Pardasani, R. T., and P. Pardasani. "Molar magnetic moment of oxovanadium(IV) derivative with bis(hydrazone) derived from 1,1′-diacetylferrocene and benzoic acid hydrazide." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 1. Springer Berlin Heidelberg, 2021. http://dx.doi.org/10.1007/978-3-662-62478-4_38.

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Pardasani, R. T., and P. Pardasani. "Molar magnetic moment of oxovanadium(IV) derivative with bis(hydrazone) derived from 1,1′-diacetylferrocene and nicotinic acid hydrazide." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 1. Springer Berlin Heidelberg, 2021. http://dx.doi.org/10.1007/978-3-662-62478-4_40.

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Pardasani, R. T., and P. Pardasani. "Molar magnetic moment of oxovanadium(IV) derivative with bis(hydrazone) derived from 1,1′-diacetylferrocene and 4-nitrobenzoic acid hydrazide." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 1. Springer Berlin Heidelberg, 2021. http://dx.doi.org/10.1007/978-3-662-62478-4_39.

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Pardasani, R. T., and P. Pardasani. "Molar magnetic moment of oxovanadium(IV) derivative with bis(hydrazone) derived from 1,1′-diacetylferrocene and 4-chlorobenzoic acid hydrazide." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 1. Springer Berlin Heidelberg, 2021. http://dx.doi.org/10.1007/978-3-662-62478-4_37.

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Conference papers on the topic "Hydrazide-Hydrazone"

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Bruckdorfer, Thomas, Pavel S. Chelushkin, Ksenia V. Polyanichko, Maria Leko, Marina Dorosh, and Sergey V. Burov. "Convenient method of peptide hydrazide synthesis using a new hydrazone resin." In 35th European Peptide Symposium. Prompt Scientific Publishing, 2018. http://dx.doi.org/10.17952/35eps.2018.084.

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Antonijević, Marko, Žiko Milanović, Dušica Simijonović, Zoran Marković, and Snežana Marković S. Zoran. "ANTIOXIDATIVE POTENCY AND RADICAL SCAVENGING ACTIVITY OF SELECTED COUMARIN-HYBRIDS." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac,, 2021. http://dx.doi.org/10.46793/iccbi21.458a.

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In previous studies, it was found that coumarins with hydrazide moiety show good antioxidative potential, while similar coumarins with hydrazone moiety are good anticancer agents. In this paper, the antioxidative potency and radical scavenging activity of two coumarin hydrazone derivatives were investigated. For this purpose, density functional theory method M062X with 6-311G++(d,p) basis set was implemented. It was found that investigated compounds exhibit good antioxidative potency, with very similar BDE values regardless of the position involved. On the other hand, PA values show that a pre

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