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Dissertations / Theses on the topic 'Hypercapnic'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Heinert, Gideon. "Hypoxic and hypercapnic cerebral vasodilatation." Thesis, University of Oxford, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.389003.

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2

Kelly, Julia Louise. "Autotitrating non-invasive ventilation (NIV) in patients with hypercapnic ventilatory failure." Thesis, Imperial College London, 2015. http://hdl.handle.net/10044/1/32008.

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Non-invasive ventilation (NIV) is an evidenced based treatment of alveolar hypoventilation in patients with hypercapnic respiratory failure (HRF). Volume assured pressure support (VAPS) is a new mode of NIV that aims to maintain alveolar ventilation (VA) by autotitration of the pressure support (PS) delivered to a patient in response to changes in respiratory physiology. The overall aim of this thesis was to investigate the use of VAPS ventilation in patients with chronic HRF during wakefulness and sleep, specifically in the detection and treatment of acute exacerbations. Specific aims were to

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3

Elhossaini, Hawraa. "Proliferation and Primitivity of Hematopoietic Progenitor Cells in Hypoxic Hypercapnic Conditions." Thesis, The University of Sydney, 2022. https://hdl.handle.net/2123/30010.

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This thesis aims to improve the in vitro cultivation of hematopoietic stem cells (HSCs) by exploring the effects of various biophysical and biochemical factors. The study uses KG-1a cells as a model for HSCs and evaluates the impact of different O2/CO2 conditions on apoptosis, proliferation, and primitivity. Additionally, the effect of differently-treated cuttlefish bone (CB) on mouse bone marrow hematopoietic cells is examined. The results show that combining hypoxia and hypercapnia is more effective in maintaining CD34+ cell count, survival, and primitivity compared to other gas combinations

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4

Tinworth, Kellie. "Arousal, Sleep and Cardiovascular Responses to Intermittent Hypercapnic Hypoxia in Piglets." Thesis, The University of Sydney, 2003. http://hdl.handle.net/2123/1116.

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Clinical studies have demonstrated an arousal deficit in infants suffering Obstructive Sleep Apnoea (OSA), and that treatment to alleviate the symptoms of OSA appears to reverse the deficit in arousability. Some sudden infant deaths are thought to be contingent upon such an arousal deficit. This research utilised young piglets during early postnatal development, and exposed them to intermittent hypercapnic hypoxia (IHH) as a model of clinical respiratory diseases. Arousal responses of control animals were compared to the animals exposed to IHH. Comparisons were also made between successive exp

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5

Tinworth, Kellie. "Arousal, Sleep and Cardiovascular Responses to Intermittent Hypercapnic Hypoxia in Piglets." University of Sydney, 2003. http://hdl.handle.net/2123/1116.

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Master of Science (Medicine)<br>Clinical studies have demonstrated an arousal deficit in infants suffering Obstructive Sleep Apnoea (OSA), and that treatment to alleviate the symptoms of OSA appears to reverse the deficit in arousability. Some sudden infant deaths are thought to be contingent upon such an arousal deficit. This research utilised young piglets during early postnatal development, and exposed them to intermittent hypercapnic hypoxia (IHH) as a model of clinical respiratory diseases. Arousal responses of control animals were compared to the animals exposed to IHH. Comparisons were

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6

Nickol, Annabel Henrietta. "Mechanism of action of nocturnal non-invasive ventilation in chronic hypercapnic respiratory failure." Thesis, Imperial College London, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.411971.

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7

Oscroft, Nicholas Stephen. "The effects of long-term non-invasive positive pressure ventilation in hypercapnic chronic obstructive pulmonary disease." Thesis, University of London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.542958.

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8

Ciarlone, Geoffrey Edward. "Hypercapnic Hyperoxia Increases Free Radical Production and Cellular Excitability in Rat Caudal Solitary Complex Brain Slice Neurons." Scholar Commons, 2016. http://scholarcommons.usf.edu/etd/6481.

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The caudal solitary complex (cSC) is a cardiorespiratory integrative center in the dorsal medulla oblongata that plays a vital role in the central CO2-chemoreceptive network. Neurons in this area respond to hypercapnic acidosis (HA) by a depolarization of the membrane potential and increase in firing rate, however a definitive mechanism for this response remains unknown. Likewise, CO2-chemoreceptive neurons in the cSC respond to hyperoxia in a similar fashion, but via a free radical mediated mechanism. It remains unknown if the response to increased pO2 is merely an increase in redox signaling

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9

Jeton, Florine. "Etude du rôle de l’Erythropoïétine et des systèmes de neurotransmission dans la mise en place des réponses ventilatoires à l’hypoxie et à l’hypercapnie." Thesis, Sorbonne Paris Cité, 2016. http://www.theses.fr/2016USPCD078/document.

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Lors de variations de PO2 et PCO2, différents mécanismes se mettent en place afin demaintenir l’oxygénation des tissus, notamment au niveau du métabolisme et de la ventilation. En casde stimulation hypoxique ou hypercapnique, on observe alors une réponse ventilatoire, caractériséepar une augmentation progressive de la ventilation. Parmi les facteurs qui influencent la réponse àl’hypoxie, on trouve l’érythropoïétine (Epo) qui, en plus de son rôle dans l’érythropoïèse, possèded’autres rôles, notamment au sein du système nerveux central. Cette thèse présente l’étude del’implication de l’Epo et de

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10

Nanagas, Vivian C. "Clamping of Intracellular pH in Neurons from Neonatal Rat Brainstem during Hypercapnia." Wright State University / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=wright1246393988.

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11

Chidambaran, Vidya. "Study of Association of FAAH Genotypes with Clinical Outcomes and Hypercapnic Ventilatory Response Related to Morphine Administration in Post-Surgical Adolescents." University of Cincinnati / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1491317932872925.

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12

Parnell, Scott E., Jayanth Ramadoss, Michael D. Delp, et al. "Chronic Ethanol Increases Fetal Cerebral Blood Flow Specific to the Ethanol-Sensitive Cerebellum Under Normoxaemic, Hypercapnic and Acidaemic Conditions: Ovine Model." Digital Commons @ East Tennessee State University, 2007. https://dc.etsu.edu/etsu-works/4134.

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Cerebral hypoxia has been proposed as a mechanism by which prenatal ethanol exposure causes fetal alcohol spectrum disorder (FASD) in children, but no study had tested this hypothesis using a chronic exposure model that mimicks a common human exposure pattern. Pregnant sheep were exposed to ethanol, 0.75 or 1.75 g kg−1 (to create blood ethanol concentrations of 85 and 185 mg dl−1, respectively), or saline 3 days per week in succession (a ‘binge drinking’ model) from gestational day (GD) 109 until GD 132. Fetuses were instrumented on GD 119–120 and studied on GD 132. The 1.75 g kg−1 dose result

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13

Eichner, Michael [Verfasser]. "Effects of thoracic trauma on in vitro efferocytic and phagocytic activity of alveolar macrophages under normoxic, hypoxic and hypercapnic conditions / Michael Eichner." Ulm : Universität Ulm, 2019. http://d-nb.info/1175526703/34.

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14

Corcione, Nadia <1984&gt. "Change in pulmonary mechanics and the effect on breathing pattern of high flow oxygen therapy in stable hypercapnic Chronic Obstructive Pulmonary Disease." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2018. http://amsdottorato.unibo.it/8627/1/tesi%20-%20DA%20INVIARE.pdf.

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Chronic hypercapnic respiratory failure (CHF) represents a major issue in stable chronic obstructive pulmonary disease (COPD). Non-invasive Ventilation (NIV) improves pulmonary gas exchange function with decrease in PaCO2 and rise in pH. Long-term NIV reduces mortality in these patients and time to first exacerbations, but adherence to ventilatory therapy is poor. High Flow Oxygen Therapy (HFOT) could counterbalance the effect of intrinsic Positive End Expiratory Pressure (PEEPi) and optimize Ventilation/Perfusion ratio through the modification of breathing pattern; then, HFOT could be an appe

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15

Wang, Zhen. "Adjunctive therapies in a clinical revelant ovine model of septic shock." Doctoral thesis, Universite Libre de Bruxelles, 2009. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210196.

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Sepsis has been defined as a systemic response to an infection. With an incidence of 3 per 1000 population per year or about 750 000 cases a year, this syndrome ranks as the 10th leading cause of death in the United States (1). Increasing severity of sepsis correlates with increasing mortality, which rises from 30-40% for severe sepsis up to 40-60% for septic shock. This thesis examines the effectiveness of adjunctive therapies, including activated protein C, hypercapnia and acidosis, and sodium selenite, in a clinically relevant ovine model of septic shock. The results from these studies can

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16

Ratliff-Rang, Christine Annette. "The Hypercapnic Ventilatory Response and Behavior in Ca2+-Activated K+ (BK) Channel Knock Out Mice And T-Cell Death-Associated Gene 8 (TDAG8) Receptor Knock Out Mice." Wright State University / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=wright1491907677483129.

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17

Bailey, Elizabeth Fiona. "Breathing behavior during speech production in hypercapnia." Diss., The University of Arizona, 1998. http://hdl.handle.net/10150/282812.

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This investigation was designed to examine speech production, the motion of the chest wall, and breathing-related perceptions under a condition of heightened respiratory drive. Ten healthy young men were studied during spontaneous breathing and during speaking in three gas conditions: room air, air delivered from a pressurized tank, and a gas mixture high in carbon dioxide (7% CO₂) delivered from a pressurized tank. Magnetometers that transduced diameter changes of the rib cage and abdomen were used to study chest wall motion. Subjects also reported their breathing-related perceptions. Results

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18

Tansley, John Guion. "Human ventilatory responses to prolonged hypoxia and hypercapnia." Thesis, University of Oxford, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.363954.

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19

Khemiri, Hanan. "Caractérisation des effets périphériques et centraux de l'érythropoïétine sur la sensibilité chimique à l'O2 et au CO2." Thesis, Aix-Marseille, 2014. http://www.theses.fr/2014AIXM5034.

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L'érythropoïétine (EPO) est une cytokine ayant un rôle important dans l'homéostasie de l'oxygène (O2). Lors d'une hypoxie chronique, l'EPO stimule la maturation des progéniteurs érythroïdes en globules rouges augmentant ainsi le transport de l'O2 aux tissus. Outre cet effet érythropoïétique, l'EPO module la réponse ventilatoire à l'hypoxie (RVH) par une action directe sur la commande centrale respiratoire (CCR) et les chémorécepteurs périphériques. Cet effet a été principalement caractérisé chez des souris mutantes surexprimant l'EPO. Cependant, plusieurs aspects de l'effet de l'EPO sur l'acti

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20

Jarsky, Tim M. "The effects of hypoxia and hypercapnia on hamster activity rhythms." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape16/PQDD_0009/MQ29356.pdf.

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21

Binks, Andrew Paul. "Breathlessness and the pattern of breathing." Thesis, University of Newcastle Upon Tyne, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.263019.

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22

Taylor, John Andrew 1960. "RESPIRATORY CHEMOSENSITIVITY IN SYNCHRONIZED SWIMMERS AND SWIM-TRAINED WOMEN." Thesis, The University of Arizona, 1987. http://hdl.handle.net/10150/276444.

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23

Delapille, Pascal. "Etude de l'activité respiratoire centrale en respiration normale et à l'issue d'apnées volontaires." Rouen, 2000. http://www.theses.fr/2000ROUEL369.

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Le but de cette étude est de rechercher, dans un premier temps, les modifications d'origine mécanique (volumes pulmonaires) et les influences d'origine chimique (tolérance à l'hypercapnie) entre 2 populations et selon différentes postures, puis dans un deuxième temps, de dissocier les facteurs chimiques et dynamiques (contractions involontaires du diaphragme) afin de montrer les effets de la durée de l'apnée et de la PACO2 sur l'activité des centres respiratoires en mesurant la ventilation (Ve), le débit inspiratoire moyen (Vt / Ti) et la pression d'occlusion (PO,1). 8 plongeurs experts et 8 t

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24

Menuet, Clément. "Vieillissement physiologique et pathologique du contrôle nerveux de la respiration : étude chez des souris sauvages et transgéniques." Thesis, Aix-Marseille 2, 2011. http://www.theses.fr/2011AIX22072/document.

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De nouveaux enjeux émergent dans le domaine de la Santé en raison du vieillissement de la population et du développement inquiétant de la Maladie d’Alzheimer (MA). Chez le sujet sain ou pathologique, peu d’études ont porté sur le vieillissement du contrôle nerveux de la respiration, en dépit de son rôle crucial pour l’oxygénation du cerveau. Cette thèse présente des recherches translationnelles, réalisées chez la souris, pour étudier le vieillissement physiologique et pathologique du contrôle nerveux de la respiration. Chez des souris transgéniques, modèles reconnus de la MA et du syndrome de

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25

Miller, Scott. "Cardiac Responses to Carbon Dioxide in Developing Zebrafish (Danio rerio)." Thèse, Université d'Ottawa / University of Ottawa, 2013. http://hdl.handle.net/10393/24210.

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The ontogeny of carbon dioxide (CO2) sensing in zebrafish (Danio rerio) has not been studied. In this thesis, CO2-mediated increases in heart rate were used to gauge the capacity of zebrafish larvae to sense CO2. CO2 is thought to be sensed through neuroepithelial cells (NECs), which are homologous to mammalian carotid body glomus cells. Owing to its role in facilitating intracellular acidification during exposure to hypercapnia, it was hypothesized that carbonic anhydrase (CA) is involved in CO2 sensing, and that inhibition of CA would blunt the downstream responses. The cardiac response

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26

Woorons, Xavier. "Conséquences physiologiques de l'entraînement en hypoventilation volontaire réalisée à de faibles volumes pulmonaires." Paris 13, 2007. http://www.theses.fr/2007PA132026.

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Cette thèse avait deux objectifs principaux 1) démontrer que l'exercice en hypoventilation volontaire (HV) réalisée à de faibles volumes pulmonaires peut entraîner une désaturation artérielle suffisamment forte pour obtenir une hypoxémie sévère 2) déterminer les conséquences physiologiques d'un entraînement en HV. Nous avons tout d'abord montré qu'une HV à de faibles volumes pulmonaires pouvait entraîner une chute de la saturation artérielle en oxygène à 87% au cours de l'exercice sous maximal. Les résultats ont également révélé que cette hypoxémie sévère s'accompagnait d'une augmentation sign

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27

VIVET, PHILIPPE. "Hypoxemie et hypercapnie diurnes chez les patients avec syndrome d'apnees du sommeil." Angers, 1989. http://www.theses.fr/1989ANGE1079.

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28

Martin, James. "The Responses of Blue Crabs (Callinectes sapidus) to Hypoxia/Hypercapnia in Freshwater." VCU Scholars Compass, 2009. http://scholarscompass.vcu.edu/etd/1847.

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The present research examined respiratory responses of blue crabs to long term (4, 13, and 21 days) hypercapnic hypoxia in freshwater at 23 C. Hypoxic conditions (50-60 & 75-85 mmHg O2) were induced by allowing the crabs to consume their oxygen supply, resulting in a hypercapnic induced decrease in pH that remained through the exposure. Postbranchial hemolymph responses to hypoxia/hypercapnia in freshwater demonstrate decreases in PO2, increases in PCO2, and decreases in pH. Lactate levels decreased over time, but hemocyanin concentration was highly variable with no trends. PH, lactate, and

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29

Abdallah, Sara. "Role of Intracellular Ca2+ and pH in CO2/pH Chemosensitivity in Neuroepithelial Cells of the Zebrafish (Danio rerio) Gill Filament." Thèse, Université d'Ottawa / University of Ottawa, 2013. http://hdl.handle.net/10393/23775.

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Neuroepithelial cells (NECs) of the zebrafish gill filament have been previously identified as bimodal O2 and CO2/H+ sensors that depolarize in response to chemostimuli via inhibition of background K+ channels. To further elucidate the signaling pathway underlying CO2/H+ chemoreception in the NECs we employed microspectrofluorometric techniques to examine the effects of hypercapnia on [Ca2+]i and pHi. NECs increased their [Ca2+]i in response to acidic hypercapnia (5% CO2, pH 6.6) and isocapnic acidosis (normocapnia, pH 6.6), but not to isohydric hypercapnia (5% CO2, pH 7.8). The acid- induced

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30

Schnedecker, Blandine. "Etude du contrôle ventilatoire par les tests d'hypoxie et d'hypercapnie progessives : application au syndrome d'apnéees du sommeil." Université Louis Pasteur (Strasbourg) (1971-2008), 1990. http://www.theses.fr/1990STR1M116.

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31

Accili, Eric Anthony. "The effects of systematic hypercapnia on the hindlimb perfusion pressures of acute spinal cats." Thesis, University of British Columbia, 1987. http://hdl.handle.net/2429/26158.

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Normal levels of CO₂ are responsible for the maintenance of approximately 30% of sympathetic neurogenic vascular tone in intact cats. The central medullary chemoreceptors have been implicated as the major source of this CO₂ dependent neurogenic vascular tone. However, it is possible that spinal cord CO₂ sensitivity could also have mediated a portion of neurogenic vascular tone. Cats with acute and chronic spinal transections can maintain near normal levels of systemic arterial blood pressure, and show cardiovascular and sympathetic reflex changes in response to a variety of stimuli. Thus, it

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32

Turner, Mark John. "The effects of hypercapnia on CFTR-dependent HCOb3p-s secretion in human airway epithelia." Thesis, University of Newcastle upon Tyne, 2014. http://hdl.handle.net/10443/2876.

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Hypercapnia is clinically defined as an arterial blood partial pressure of CO2 of above 40mm Hg and is a symptom of chronic lung disease. In renal epithelia, hypercapnia can reduce agonist-stimulated cAMP levels and impair regulation of cAMP-dependent ion transporters. In the airways, elevations in intracellular cAMP in serous cells of the submucosal glands, activates CFTR-mediated HCO3- and fluid secretion, which contributes to airway surface liquid homeostasis. The aim of the current work was to investigate the effects of both acute and chronic hypercapnia on cAMP-regulated ion and fluid tra

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33

Kunert, Emma. "The Role of Carbonic Anhydrase in Cardiorespiratory Responses to CO2 in Zebrafish (Danio rerio)." Thesis, Université d'Ottawa / University of Ottawa, 2021. http://hdl.handle.net/10393/42098.

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Adaptation to environmental fluctuations, through sensing and appropriate physiological responses, is crucial to homeostasis. Neuroepithelial cells (NECs) are putative chemoreceptors resembling mammalian Type I (glomus) cells. They have been shown to respond in vitro to changes in O2, CO2, NH3 and pH. Cytosolic carbonic anhydrase (Ca17a) is thought to be involved in CO2 sensing owing to its presence in NECs. A mutant line of zebrafish (Danio rerio) lacking functional Ca17a was generated using CRISPR/Cas9 technology and used to assess the role of Ca17a in initiating the cardiorespiratory respon

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34

JIRARI, AMINE. "Syndrome d'apnee du sommeil et etude retrospective : etude des anomalies gazometriques ; etude d'un questionnaire soumis aux candidats a la polygraphie ; a propos de 87 patients." Nice, 1992. http://www.theses.fr/1992NICE6531.

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35

Croft, Quentin. "Human responses to simulated high altitude." Thesis, University of Oxford, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.711614.

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36

Heyer, Laurent. "Effets respiratoires du propofol et de l'halothane chez le jeune enfant." Lyon 1, 1993. http://www.theses.fr/1993LYO1M336.

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Bartlett, Kate. "Changes in Cortical Tissue Oxygenation in rodent somatosensory cortex produced by sensory stimuli and hypercapnia." Thesis, University of Sheffield, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.500531.

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38

Hypes, Sandra R. "Sub-Lethal Effects of Hypoxia/Hypercapnia on Callinectes Sapidus in the York River Estuary, Virginia." VCU Scholars Compass, 1999. http://scholarscompass.vcu.edu/etd/1346.

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This research examined effects of hypoxic environments on blue crabs, Callinectes sapidus in an estuarine environment. Hypoxic conditions were treated as a multiple stressor involving low dissolved oxygen (D.O.), increased carbon dioxide (hypercapnia), and low pH concurrently. The objectives were to: 1) identify hypoxiahypercapnia by monitoring D.O. and pH as an indicator of hypercapnia in shallow regions of the York River, 2) measure blue crab abundance, and 3) describe blue crab responses to hypoxiahypercapnia via field work at Taskinas Creek and lab measurements of respiration. Ambient D.O.

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Marschand, Rachel E. "Effects of Airway Pressure, Hypercapnia, and Hypoxia on Pulmonary Vagal Afferents in the Alligator (Alligator Misssissippiensis)." Thesis, University of North Texas, 2013. https://digital.library.unt.edu/ark:/67531/metadc407750/.

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The American alligator (Alligator mississippiensis) is an aquatic diving reptile with a periodic breathing pattern. Previous work has identified pulmonary stretch receptors (PSR), both rapidly- and slowly-adapting, and intrapulmonary chemoreceptors (IPCs) that modulate breathing patterns in alligators. The purpose of the present study was to identify the effects of prolonged lung inflation and deflation (simulated dives) on PSR and/or IPC firing characteristics in the alligator. The effects of airway pressure, hypercapnia, and hypoxia on dynamic and static responses of pulmonary stretch recept

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Hammer, Karen M. "Acid-base regulation and metabolite responses in shallow- and deep-living marine invertebrates during environmental hypercapnia." Doctoral thesis, Norges teknisk-naturvitenskapelige universitet, Institutt for biologi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-19773.

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Global warming is considered to be the most adverse consequence from the increasing anthropogenic emissions of CO2. However, in the marine environment additional problems related to the elevated levels atmospheric CO2 may arise; the increased amount of CO2 absorbed by the oceans may lead to a moderate, but consistent and global reduction in seawater pH due to the acidifying effect of CO2, a phenomenon referred to as ocean acidification. Another potential problem may occur as a result of sub-seabed storage of anthropogenic CO2, a disposal alternative introduced by the gas industry to mitigate C

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Hamad, Mouna. "Toward an Understanding of How Hypercapnia Affects Apoptosis in Human Promyeloblasts in 3D Suspension Culture Systems." Thesis, The University of Sydney, 2017. http://hdl.handle.net/2123/16960.

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Stem cells have more recently attracted interest in scientific research and their use is increasingly developing in many therapeutic applications. A great deal of cell-based work is conducted at 5% CO2 concentration and is predominantly cultured on two-dimensional surfaces. These methods are straightforward and of low economic costs but do not necessarily replicate the microenvironment; also, evidence to provide justification for selecting this specific concentration of CO2 in hematopoietic progenitor cell (KG-1a) proliferation studies is lacking. Our work herein pursues to prove the following

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42

Berquin, Patrick. "Mise en évidence des neurones impliqués dans les mécanismes d'adaptation à l'hypoxie et à l'hypercapnie chez l'animal adulte et au cours du développement postnatal : étude immunohistochimique de l'expression de c-fos au niveau du tronc cérébral et de l'hypothalamus." Amiens, 1999. http://www.theses.fr/1999AMIED007.

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Les réponses à l'hypoxie et l'hypercapnie font intervenir différentes structures du névraxe. Les populations neuronales activées au cours de l'hypoxie ou de l'hypercapnie modérées ont été visualisées par une technique immunohistochimique de détection de l'expression c-fos au niveau du tronc cérébral et de l'hypothalamus. Chez le chat et le rat adultes, l'expression de c-fos est évoquée par les 2 types de stimulation au niveau du noyau du faisceau solitaire, de l'aire parabrachiale, de la substance grise périaqueducale, de l'hypothalamus caudal (noyaux hypothalamique postérieur, dorsomédian), d

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43

Jacoupy-Essouri, Sandrine Fauroux Brigitte. "Insuffisance respiratoire aiguë hypercapnique de l'enfant bases physiopathologiques et implications pour la ventilation mécanique noninvasive /." Créteil : Université de Paris-Val-de-Marne, 2007. http://doxa.scd.univ-paris12.fr:8080/theses-npd/th0367739.pdf.

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44

Dodd, Graham Alan Andrew. "The effects of acute and chronic hypercapnia upon ventilation and acid-base status in the pekin duck." Thesis, University of British Columbia, 1989. http://hdl.handle.net/2429/27417.

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In this study, awake Pekin ducks (Anas platyrhynchos) were exposed to periods of acute and chronic hypercapnia (0.05 F₁CO₂). Measurements were made of ventilation and acid-base status in both adult and juvenile male ducks as well as in adult female ducks. All Pekin ducks, regardless of age or sex, responded acutely to inspired CO₂ with a marked hypercapnic-hyperpnea. Inhalation of CO₂ resulted in a significant increase in arterial CO₂ tension (PaCO₂) and decrease in arterial pH (pHa). The increase (3 times (x)) in minute ventilation (V[sub E]), while primarily a function of an increase (2x) in

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45

Najarian, Taline. "Hypercapnia-induced, potassium channel and prostaglandin dependent modulation of endothelial constitutive nitric oxide synthase in neonatal brain." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0034/MQ64414.pdf.

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Buchbinder, Benno Andreas [Verfasser]. "Impact of hypercapnia on alveolar Na+-transport : Establishing a system for ENaC-protein detection / Benno Andreas Buchbinder." Gießen : Universitätsbibliothek, 2013. http://d-nb.info/1065478976/34.

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Kiely, David Gerard. "Cardiopulmonary interactions of hypoxia and hypercapnia and the role of vasoactive mediators in the pulmonary circulation in man." Thesis, University of Edinburgh, 2000. http://hdl.handle.net/1842/22375.

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We have examined the cardiopulmonary effects of hypoxia and hypercapnia in the integrated physiological system of normal man using non-invasive pulsed-wave Doppler echocardiography and phonocardiography and have extended this work to study the role vasoactive mediators in the pulmonary circulation in man. We have demonstrated that systolic and diastolic function are unaffected by acute hypercapnia in normal man. Acute hypoxaemia significantly impairs both right and left ventricular diastolic function, in a dose dependent manner, although systolic function remains well preserved. In addition to

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Ratnavadivel, Rajeev, and rajeev ratnavadivel@health sa gov au. "The Importance of Non-Anatomical Factors in the Pathogenesis of Obstructive Sleep Apnoea." Flinders University. Medicine, 2009. http://catalogue.flinders.edu.au./local/adt/public/adt-SFU20090901.162141.

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Obstructive sleep apnoea (OSA) is a common condition characterized by recurrent complete and partial upper airway obstruction. OSA sufferers have been shown to have a significantly smaller upper airway lumen compared to non-OSA sufferers. However, non-anatomical factors of sleep stage, arousability and neuromechanical responses to airway occlusion and chemosensitivity are likely to play a significant part in influencing OSA severity across the night. An exploration of these non-anatomical factors forms the basis for the experiments in this thesis. In the first experimental chapter presented i

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Fehsenfeld, Sandra. "Linking acid-base balance with nitrogen regulation in the decapod crustacean, Carcinus maenas." Comparative Biochemistry and Physiology, Part A, 2013. http://hdl.handle.net/1993/30977.

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As one of the most successful invasive species in the marine environment around the globe, the green crab Carcinus maenas possesses efficient regulatory mechanisms to quickly acclimate to environmental changes. The most important organs in this process are the nine pairs of gills that not only allow for osmoregulation, but have been shown to be involved in ammonia excretion and respiratory gas exchange. To date, however, little is known about the gills’ contribution to acid-base regulation that might become increasingly important in a “future ocean scenario” whereby surface ocean pH is predict

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Toshiyuki, Mizota. "The clinical course of anesthetic induction in lung transplant recipients." Kyoto University, 2015. http://hdl.handle.net/2433/202778.

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