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Dissertations / Theses on the topic 'IL-5'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Lundberg, Elin. "Utomståenderegeln i 57:5 IL." Thesis, Jönköping University, JIBS, Commercial Law, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-12225.

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<p><strong><p>Abstract</p><p>This bachelor thesis deals with the close company rules in chapter 56-57 within the Swedish income tax law (IL). The purpose of this thesis is to analyse the outsider rule in 57:5 IL. If a shareholder or a family member works or have worked actively within the company within the fiscal year or the last five fiscal years then the partner has qualified shares and is to be taxed according to the special closed company rules.</p><p>If an outsider, directly or indirectly, is a significant shareholder within the company, and directly or indirectly, are entitled to divide

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2

Krisiukėnienė, Algirda. "Rūkymo sąlygoti imuninio atsako ypatumai sergant astma." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2009. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2009~D_20090604_110354-67472.

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Astma-lėtinė kvėpavimo takų liga, pasireiškianti dusulio ar kosulio epizodais bei padidėjusiu bronchų reaktyvumu. Eksperimentiniai bei klinikiniai tyrimai parodė, kad lėtinis neinfekcinis kvėpavimo takų uždegimas- svarbiausia astmos patogenezės grandis, lemianti šios ligos klinikinę eigą, sunkumą bei skiriamo gydymo efektyvumą. Nėra aišku, ar alerginė bei nealerginė astma skiriasi ne tik klinikiniu pasireiškimu, bet ir patomorfologiniais bei patofiziologiniai kvėpavimo takų pakitimais. Rūkymas- svarbus veiksnys, sukeliantis reikšmingus pokyčius kvėpavimo takų gleivinėje. Tačiau kaip rūkymas įt

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3

Nilsson, Linda, and Jenny Palm. "Utomståenderegeln 57 kap 5§ IL - är den ändamålsenlig?" Thesis, Kristianstad University College, Department of Business Administration, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:hkr:diva-3767.

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<p>Uppsatsens syfte är att beskriva vad utomståenderegeln innebär, vilka rekvisit som måste uppfyllas för att den ska vara tillämpbar och om den är ändamålsenlig enligt lagstiftarens syfte. Metoden som används är den rättsdogmatiska rättsvetenskapen, vilken innebär att en redogörelse gör för gällande rätt med hjälp av de olika rättskällorna, lag, förarbeten, praxis och doktrin. För att ge en helhetsbild används exempel för att illustrera olika situationer.</p><p>Till kategorin fåmansföretag räknas aktiebolag och ekonomisk förening, där fyra eller färre fysiska personer äger, direkt eller indir

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4

Stomski, Frank Charles. "The molecular basis of IL-3, Il-5 and GM-CSF receptor activation /." Title page, contents and abstract only, 1997. http://web4.library.adelaide.edu.au/theses/09PH/09phs8766.pdf.

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5

Porte, Liliane Medianeira Favero. "Síntese de 5-hidróxi-3-(1,1-dimetoxietan-2-il)-5-trifluormetil-2-pirazolinas e 3-(1,1-difluoretan-2-il)-1H-pirazóis análogos." Universidade Federal de Santa Maria, 2008. http://repositorio.ufsm.br/handle/1/10417.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>This work describes, at first, the synthesis of 4,6,6-trimethoxy-1,1,1-trifluorohex-3-en-2-one by the acylation reaction of 1,1,3,3-tetramethoxybutane, in 65% yields. Afterwards, the synthesis of a new series of 4,5-dihydro-1H-pyrazoles, which contain a ketal-protected aldehyde function as substituent, is described. These compounds are obtained by the reaction of 4,6,6-trimethoxy-1,1,1-trifluorohex-3-en-2-one with hydrazines (NH2NHR, R= 2-furoyl, C6F5, COOMe, COMe, Nicotinoyl), in 90-97% yields. In a subsequent step, dehydration re

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6

Paim, Gisele Rocha. "Síntese de 2-(1h-pirazol-1-il)-5-(1h-pirazol-1-il-1-carbonil) piridinas." Universidade Federal de Santa Maria, 2008. http://repositorio.ufsm.br/handle/1/10419.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>This work describes the synthesis of a new series of 2-[3-alkyl(aryl/heteroaryl)-5-trihalomethyl-5-hydroxy-4,5-dihydro-1H-pyrazol-1-il]-5-[3-alkyl(aryl/heteroaryl)-5-trihalomethyl-5-hydroxy-4,5-dihydro-1H-pyrazol-1-il-1-carbonyl]pyridines by the cyclocondensation reaction of 1,1,1-trihalo-4-alkoxy-4-alkyl(aryl/heteroaryl)-3-alken-2- ones [CX3C(O)CH=CR1OR, where R = Me, Et; R1 = H, Me, Ph, 4-MeOPh, 4-NO2Ph, 4,4 -Biphenyl, 1-Naftyl, 2-Furyl, 2-Thienyl and X = F, Cl] with 6-hydraninonicotinic hydrazide hydrate. Yields of 67 to 97% was

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7

Nogara, Pablo Andrei. "Síntese de (5-trifluormetil-1H-pirazol-1-IL)(quinolin-4-IL)metanonas de interesse farmacológico." Universidade Federal de Santa Maria, 2016. http://repositorio.ufsm.br/handle/1/10627.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>A convergent synthesis of a series of 16 new polysubstituted (5-hydroxy-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-1-yl)(quinolin-4-yl)methanones, starting from isatin and alky(aryl/heteroaryl) ketones, is described. The diheteroaryl methanones were achieved at yields of up to 95% by a (3 + 2) cyclocondensation reaction involving 4-alkyl(aryl/heteroaryl)-4-methoxy-1,1,1-trifluorobut-3-en-2-ones (by two-step reaction) and 2-alkyl(aryl/heteroaryl)-4-carbohydrazides (by three-step reaction). Subsequently, representative dehydrated het

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8

Monduzzi, Pietro. "Applicare il design thinking a progetti ad elevato TRL (5-7): riflessioni metodologiche e il caso M.A.T.R.I.C.S." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2022.

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La ricerca presentata nell’elaborato trova origine a seguito dell’esperienza maturata nel progetto M.A.T.R.I.C.S., in cui si è cercato di applicare il design thinking in un contesto che vede una tecnologia a TRL elevato (5-7) e, dunque, con vincolo tecnologico.  Il team di progetto si è accorto del fatto che fosse necessario uscire dagli schemi dell’approccio tradizionale per creare valore, e si è riadattato in corso d’opera, al fine di includere la prospettiva human-centred in un ambiente fortemente vincolato dal campo applicativo e con una tecnologia scelta (vincolo tecnologico) per ricoprir

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9

Sun, Qiyu. "Human GM-CSF, IL-3 and IL-5 receptor expression and their functional domains studied with monoclonal antibodies /." Title page, contents and abstract only, 1997. http://web4.library.adelaide.edu.au/theses/09PH/09phs9569.pdf.

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10

Rosales, Pauline Fagundes. "Bi-heterociclos a partir do Ácido Levulínico: Síntese de 5-[(5-(trifluormetil)-5-hidroxi-(3-substituido)-4,5-diidro-1H-pirazol-1-il)-1-propan-1-ona-3-il]-2-metil-7-trifluormetil)pirazolo[1,5-a]pirimidinas." Universidade Federal de Santa Maria, 2013. http://repositorio.ufsm.br/handle/1/10535.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>An efficient method to obtain 2-methyl-5-(methylpropanoate-3-yl)-7-trifluoromethylpyrazolo[1,5-a]pyrimidine 2 from the reaction of compound methyl 7,7,7-trifluoro-4-methoxy-6-oxo-heptenoate with 3-amino-5-methyl-1H-pyrazol. This compound 2 brought to reaction with hydrazine monohydrate to obtain 2-methyl-7-trifluoromethylpyrazolo[1,5-a]pyrimidine-5-propanehydrazine 3 and after were later brought to cyclocondensation reaction with a series of β-alkoxyvinyltrifluoromethyl ketones giving the series of news bi-heterocyclic 5-[(5-(trifl

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11

Borgwardt, Derek Steven. "Histatin 5 attenuates IL-8 dendritic cell response to gingivalis Hemagglutinin B." Thesis, University of Iowa, 2011. https://ir.uiowa.edu/etd/926.

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Histatins, a group of proteins produced by human salivary glands, have a variety of innate immune functions including the ability to: kill oral microorganisms, neutralize toxins, inactivate protease/collagenase activities, inhibit co-aggregation of oral bacteria, and inhibit lipopolysaccharide mediated activities. Hemagglutinin B (HagB), a virulence factor of the periodontal pathogen Porphyromonas gingivalis, induces a robust cytokine and chemokine response in human myeloid dendritic cells. In this study, I hypothesize that histatin 5 can attenuate a HagB-induced chemokine response. Objectives

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12

VIGANO', ELENA. "Study of caspase - 5 regulation during inflammasome activation in human monocytes." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2014. http://hdl.handle.net/10281/52430.

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The NLRP3 inflammasome is a multiprotein complex regulating the secretion of IL-1β and IL-18 in response to a variety of stimuli, including pathogen- and danger-associated molecular patterns (PAMPs and DAMPs). Upon activation, the apoptosis associated speck-like protein (ASC) adaptor recruits caspase-1 to the NLRP3 inflammasome complex, where it first undergoes auto-cleavage and then processes the inactive precursors of IL-1β and IL-18. Importantly, NLRP3 is not responsive to stimulation unless primed by an NF-κB-triggering signal, such as LPS. Recent studies have identified an alternative mec

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13

Fiss, Gabriela Fehn. "Síntese de 2-[5-Aril-3-(E-estir-1-il)-4,5-Diidro-1H-pirazol-1-il]-4-Fenil-6-Trifluormetilpirimidinas." Universidade Federal de Santa Maria, 2005. http://repositorio.ufsm.br/handle/1/10636.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico<br>The synthesis of a series of 2-[5-aryl-3-(E-styr-1-yl)-4,5-dihydro-1H-pyrazol-1-yl]-4-phenyl-6-trifluoromethylpyrimidines (where aryl = C6H5, 2-MeC6H4, 2-MeOC6H4, 4-MeOC6H4, 3,4-(MeO)2C6H3, 3,4,5-(MeO)3C6H2, 4-ClC6H4) in 61-99% yields from the cyclocondensation reaction of 5-aryl-3-(E-styr-1-yl)-4,5-dihydro-1H-pyrazol-1-carboxamidines with 1,1,1-trifluoro-4-methoxy-4-phenyl-3-buten-2-one in the presence of catalytic amounts of BF3⋅OEt2, dichloromethane as solvent at room temperature (20-25 °C) for 15 minutes, is reported. The 5-a

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14

Lystedt, Edin Josephine. "Omfattningen av begreppet delägare i handelsbolag i 22:3 och 23:5 IL : En kritisk granskning av HFD 2015 ref. 30." Thesis, Uppsala universitet, Juridiska institutionen, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-272538.

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15

Romeo, Diego. "Dal post al commento: la lingua e il discorso del Movimento 5 Stelle." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2017. http://amslaurea.unibo.it/13777/.

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La politica ha ormai da alcuni anni abbracciato la Rete. Internet offre un’immediatezza preziosa e senza precedenti in fatto di comunicazione, sia perché consente un inedito senso di vicinanza tra elettori ed eletti, sia perché permette a partiti e politici di discutere ogni questione nei termini a loro più congeniali. Il blog di Grillo, da sempre il più seguito d’Italia e oggi fulcro ideologico del Movimento 5 Stelle, è in questo senso precursore, avendo fatto la sua comparsa ben prima delle grandi reti sociali di cui oggi la maggior parte dei politici si serve. Data la grande rilevanza assun

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16

Maccanico, Roberta <1992&gt. "Turismo di lusso e hotel 5 stelle a Venezia. Il caso dell'Hotel Bauer." Master's Degree Thesis, Università Ca' Foscari Venezia, 2018. http://hdl.handle.net/10579/12392.

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L’elaborato ha come oggetto il fenomeno del luxury tourism, segmento in costante evoluzione. Ci si concentrerà sul concetto di lusso rapportato all’ambito alberghiero, prendendo in esame alcune celebri catene operanti nel suddetto segmento presenti sul territorio veneziano. In particolare, verrà esaminato il caso dell’Hotel Bauer, storica struttura con anni di tradizione ed esperienza nell’accoglienza dei clienti alle spalle. Il discorso si articolerà partendo da una contestualizzazione del fenomeno turistico in generale, delineando le principali tappe che hanno portato al turismo come lo cono

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17

Silva, Tarcimara Moreira da. "Perfil das citocinas IL-4, IL-5, IL-8 e IFN- analisadas por RT-PCR em tecido de mucosa nasal de pacientes portadores de rinite alérgica." Universidade Federal de Minas Gerais, 2007. http://hdl.handle.net/1843/ECJS-772Q3Q.

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The allergic rhinitis is an inflammatory reaction of the nasal mucosa, in consequence of the hypersensitive reaction to inhaling allergens and, eventually, alimentary, mediated by IgE, involving different mediators and cytokines cells. The purpose of this study was to evaluate the transcriptions for the following cytokines: IL-4, IL-5, IL- 8 and IFN-ã, particularly important in the allergic nasal process, mainly IL-4 and IL-5, following one of the research lines of the Otorhinolaryngology Service of UFMG. In this study, it was opted to evaluate the atopic patients that were free from allergic

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18

Mortuaire, Geoffrey. "Modulation des mécanismes inflammatoires impliquant les polynucléaires éosinophiles au cours de la polypose naso-sinusienne associée à l'asthme." Thesis, Lille 2, 2015. http://www.theses.fr/2015LIL2S010/document.

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Contexte : La polypose naso-sinusienne (PNS) est une maladie inflammatoire chronique multifactorielle dont l’étiologie reste imprécise. Les acteurs de l’immunité innée et acquise sont diversement impliqués avec un rôle central joué par l’éosinophile(EO). L’asthme associé à la PNS est un facteur de résistance à la corticothérapie constituant à l’heure actuelle la seule option thérapeutique médicale.Objectifs : Caractériser sur le plan histologique, biologique et cellulaire les patients atteints de PNS afin de définir des profils phénotypiques inflammatoires en relation avec l’asthme et de préci

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19

Souza, Alessandra Hübner de. "Avaliação do potencial antinociceptivo e mecanismo de ação do 2-[5-triclorometil-5-hidroxi-3-fenil-4,5-dihidro-1hpirazol- 1-il] 4-(4 bromofenil)- 5 metiltiazol (b50) em camundongos." Universidade Federal de Santa Maria, 2005. http://repositorio.ufsm.br/handle/1/11110.

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Pain is a common symptom in the clinical practice. Therefore, novel analgesic drugs, with more favorable pharmacological properties have been searched. Previous studies from our group showed that the systemic administration of the 2-[5-triclorometyl-5-hidroxy-3-phenyl-4,5-dihydro-1H-pyrazole-1-yl]-4-(4-bromophenyl)-5-metyl-thiazole(B50) causes antinociception in the acetic acid writhing test. However, it is not know whether such an antinociceptive action involves central or peripheral mechanisms. In this study we investigated the antinociceptive effect of the intrathecal administration of the

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20

Soares, Pedro Marcos Gomes. "Mucosite intestinal experimental induzida por 5-fluorouracil : papel de IL-1β, IL-4 e PAF e avaliação das alterações da motilidade digestiva". reponame:Repositório Institucional da UFC, 2008. http://www.repositorio.ufc.br/handle/riufc/3740.

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SOARES, Pedro Marcos Gomes. Mucosite intestinal experimental induzida por 5-fluorouracil : papel de IL-1ß, IL-4 e PAF e avaliação das alterações da motilidade digestiva. 2008. 142 f. Tese (Doutorado em Farmacologia) - Universidade Federal do Ceará. Faculdade de Medicina, Fortaleza, 2008.<br>Submitted by denise santos (denise.santos@ufc.br) on 2012-09-06T12:15:24Z No. of bitstreams: 1 2008_tese_pmgsoares.pdf: 14518787 bytes, checksum: 6a4dbe6ae7c642ebca0081619b1b39a2 (MD5)<br>Approved for entry into archive by Eliene Nascimento(elienegvn@hotmail.com) on 2012-09-06T12:25:49Z (GMT) No. of bitstr

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21

Oliveira, Lanussy Porfiro de. "Atividade analgésica, anti-inflamatóriae vasorelaxante de dois derivados pirazólicos: 5-[1-(4- fluorfenil)-1H-pirazol-4-IL]-2H-tetrazola(LQFM 020) e 5- [1-(2-fluorofenil)-1H-pirazol-4-IL]-2H-tetrazola (LQFM 039)." Universidade Federal de Goiás, 2014. http://repositorio.bc.ufg.br/tede/handle/tede/4876.

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Submitted by Cláudia Bueno (claudiamoura18@gmail.com) on 2015-11-11T20:45:46Z No. of bitstreams: 2 Dissertação - Lanussy Porfiro de Oliveira - 2014.pdf: 1478536 bytes, checksum: 2646f221282c9b288ef2da403ef374d4 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)<br>Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2015-11-12T09:40:17Z (GMT) No. of bitstreams: 2 Dissertação - Lanussy Porfiro de Oliveira - 2014.pdf: 1478536 bytes, checksum: 2646f221282c9b288ef2da403ef374d4 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b

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Soares, Pedro Marcos Gomes. "Mucosite intestinal experimental induzida por 5-fluorouracil: Papel de IL-1β, IL-4 e PAF e avaliaÃÃo das alteraÃÃes da motilidade digestiva." Universidade Federal do CearÃ, 2008. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=1456.

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Conselho Nacional de Desenvolvimento CientÃfico e TecnolÃgico<br>Objetivos: Avaliar os mediadores inflamatÃrios e as alteraÃÃes motoras gastrintestinais no curso da mucosite intestinal experimental induzida por 5-FU. MÃtodos: Para avaliar as citocinas utilizamos camundongos balb-c ou c57/black (25-30g), tratados com IL-1Ra (100mg/Kg, i.p., diariamente) ou deficientes para IL-4 (IL-4 -/-) ou para IL-18 (IL-18 -/-). A fim de estudar a participaÃÃo de PAF e 5-LO, utilizamos o BN52021 (20mg/Kg, s.c., diariamente) ou camundongos deficientes para o receptor de PAF (PAF -/-) ou para 5-LO (5-LO -/-).

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23

McCormack, Matthew Paul. "The biological effects of constitutively active mutants of the common [beta] subunit of the human IL-3, IL-5 and GM-CSF receptors /." Title page, contents and abstract only, 1998. http://web4.library.adelaide.edu.au/theses/09PH/09phm1305.pdf.

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Thesis (Ph.D.)--University of Adelaide, Dept. of Medicine, 1999?<br>Amendments to thesis in pocket on back cover. Copy of author's previously published article in pocket on back cover. Bibliography: leaves 124-172.

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24

Marangoni, Mário André. "Síntese de 4-trifluormetil-5-(propan-1-ol-3-il)-1H-piridin-2-iminas Nsubstituídas." Universidade Federal de Santa Maria, 2013. http://repositorio.ufsm.br/handle/1/10540.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>This work presents a simple and accessible synthetic route for the preparation of a series, of nineteen new N-substituted 4-trifluormethyl-5- (propan-1-ol-3-yl)-pyridin-2-(1H)-imines, obtained from the reaction between 3- (3,4-dihydro-2H-pyran-5-yl)-4,4,4-trifluorobut-2-enenitrile with the following amines: methylamine, ethylamine, propylamine, iso-propylamine, butylamine, sec-butylamine, benzylamine, phenethylamine, 2-methoxy-phenethylamine, 4- methoxy-phenethylamine, 3,4-methoxy-phenethylamine, 4-fluorophenethylamine, 2-chloro-ph

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25

Dumont, Adélie. "L'action ambivalente de l'agent anti-cancéreux 5-Fluorouracile sur les cellules myéloïdes immunosuppressives sous contrôle de l'acide docosahexaénoïque : Rôle de l'inflammasome NLRP3 et de la voie JNK dans la sécrétion de l'IL-1beta." Thesis, Bourgogne Franche-Comté, 2018. http://www.theses.fr/2018UBFCI013/document.

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Selon une étude précédente, une limitation à l'efficacité anticancéreuse du 5-Fluorouracile (5-FU) repose sur la sécrétion d'IL-1β par des cellules myéloïdes immunosuppressives (MDSC). La libération d'IL-1β mature provient de l'activation de NLRP3 induite par le 5- FU et de l’augmentation de l’activité de la caspase-1 dans les MDSC, qui favorise la reprise de la croissance tumorale chez des souris traitées avec 5-FU. L'acide docosahexaénoïque (DHA) appartient à la famille des acides gras oméga-3 et possède des propriétés anticancéreuses et anti-inflammatoires qui pourraient améliorer la chimio

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Grund, Lidiane Zito. "Papel das citocinas IL-5 e IL-17A na diferenciação de células produtoras de anticorpos de vida longa (ASC) induzida pelo veneno do peixe Thalassophryne nattereri." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/42/42133/tde-09022010-114250/.

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O veneno do T.nattereri induz uma resposta de memória com a diferenciação de células B B220neg, indicativo de células produtoras de anticorpos de vida longa (ASC). Para avaliar o efeito do veneno na diferenciação de ASCs, camundongos BALB/c foram imunizados e sacrificados nos dias 21, 28, 48, 74 e 120 para avaliação de anticorpos plasmáticos e células B no peritônio, baço e medula óssea. O veneno induziu intensa esplenomegalia, formação de centros germinativos e persistentes níveis de anticorpos específicos IgG1, IgG2a e IgE anafilática. Células B1a e ASC apareceram rapidamente e a população d

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27

Colin, Olivier. "L'enfant autiste en-jeu, joue-t-il un jeu ludique ? : évaluation du niveau ludique du jeu chez 5 enfants autistes et 5 enfants témoins." Montpellier 1, 1996. http://www.theses.fr/1996MON11107.

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28

Gartenschläger, Sören. "Untersuchung der Interleukin-5-Rezeptor-Expression und der Aktivierung humaner eosinophiler Granulozyten Einfluss von Interferon [gamma], transforming growth factor [beta]1 sowie der hämatopoetischen Zytokine IL-3, IL-5 und GM-CSF auf den Aktivierungsmarker CD69 sowie auf die Interleukin-5-Rezeptor-[alpha]-Expression humaner eosinophiler Granulozyten /." [S.l.] : [s.n.], 1999. http://deposit.ddb.de/cgi-bin/dokserv?idn=963698958.

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Bergami, Giulia. "Il paleolago del Timpone Pataso nel contesto evolutivo del Monte Sant'Angelo (Lipari) durante l'Epoca Eruttiva 5." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2020.

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In questo lavoro di tesi si è proceduto ad analizzare i depositi piroclastici delle Epoche Eruttive 5a e 5b relative all’attività del Monte Sant'Angelo nell’intervallo temporale tra <114 e 104 ka. Sono state analizzate in dettaglio le sequenze di depositi delle formazioni Timpone Pataso e Serra Pirrera e la loro origine è stata ricondotta a pyroclastic density current (PDC), a variabile concentrazione e contenuto d'acqua (wet), come testimoniato anche dalla presenza di strutture da slumping, di frane sin deposizionali e della presenza di resti vegetali (Chamaerops humilis, Laurus, Pinus, Querc

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Borri, Enza. "Progettazione sismica di un edificio a 5 piani in c.a. secondo il D.M.14/01/2008." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2010. http://amslaurea.unibo.it/1328/.

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Ratto, Neto Carlos Alberto. "Planejamento, síntese e caracterização de derivados do 9,10-bis(5-fenil-1,3,4-oxadiazol-2-IL)Antraceno." reponame:Repositório Institucional da UFSC, 2015. https://repositorio.ufsc.br/xmlui/handle/123456789/133216.

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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2015<br>Made available in DSpace on 2015-06-02T04:07:50Z (GMT). No. of bitstreams: 1 333783.pdf: 2392904 bytes, checksum: bfaf8671475ab5ad53a518e5ffa9d85b (MD5) Previous issue date: 2015<br>Neste trabalho é descrito o planejamento, síntese e caracterização de uma série de novos compostos contendo o centro 9,10-bis(5-fenil-1,3,4-oxadiazol-2-il)antraceno com sua geometria planejada de modo a apresentar propriedades líquido-cristalinas.

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Mirey, Emilie. "L' interleukine-33, un nouvel acteur de la réponse anti-tumorale dans un modèle murin de cancer du côlon." Toulouse 3, 2014. http://www.theses.fr/2014TOU30116.

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L'interleukine-33 (IL-33) est une cytokine nucléaire de la famille des interleukines-1. L'IL-33 est exprimée par de nombreux épithéliums en contact avec l'environnement et peut être libérée sous sa forme pleine taille lors de nécrose. Cette forme active peut interagir avec le récepteur ST2 appartenant à la famille des récepteurs de l'IL-1 (IL-1R4). ST2 est présent sur de nombreuses cellules du système immunitaire aussi bien impliquées dans l'immunité innée (cellules lymphoïdes innées de type 2 ou ILC2, mastocytes, NK,. . . ) qu'adaptative (lymphocytes Th2, T CD8,. . . ). L'ensemble de ces prop

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Codlin, Sandra Maria Susan. "A novel palindromic element common to the granulocyte macrophage colony stimulating factor gene and the Th2 expressed cytokine genes : interleukin (IL) 4, IL 5 and IL 13 acts as a potent enhancer of transcription." Thesis, King's College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.249674.

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Su, Yung-Chang University of New South Wales &amp Garvan Institute of Medical Research St Vincent's Clinical School UNSW. "Immune regulation in mouse models of allergic asthma." Awarded by:University of New South Wales & Garvan Institute of Medical Research. St. Vincent's Clinical School, 2006. http://handle.unsw.edu.au/1959.4/26978.

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Allergic asthma is an immunological disease, mediated by CD4+ Th2 cells, and its prevalence has increased over recent decades. Features of allergic asthma include airway hyperresponsiveness (AHR), airway eosinophilia, excessive airway mucus production, and increased IgE and Th2 cytokine levels. Airway remodeling with pulmonary fibrosis is noted in the progress of asthma. In this thesis, a murine model of allergic asthma was used to investigate the effect of cyclophosphamide (CY) on asthma and the involvement of regulatory T cells (Treg), and the role of Granulocyte-macrophage colony stimulatin

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Sakiyama, Toshio. "Requirement of IL-5 for induction of autoimmune hemolytic anemia in anti-red blood cell autoantibody transgenic mice." Kyoto University, 2000. http://hdl.handle.net/2433/151441.

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Christianne, Batista de Lacerda Pedrosa Sybelle. "Síntese, caracterização e avaliação antitumoral de novos derivados 3-Benzil-5-(Indol-3-il-Metileno)-Tiazolidina-2,4-Diona." Universidade Federal de Pernambuco, 2011. https://repositorio.ufpe.br/handle/123456789/3657.

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Made available in DSpace on 2014-06-12T16:32:48Z (GMT). No. of bitstreams: 2 arquivo6584_1.pdf: 750267 bytes, checksum: b8b39d466d0551d86f2d927a7175838b (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) Previous issue date: 2011<br>Fundação de Amparo à Ciência e Tecnologia do Estado de Pernambuco<br>The thiazolidine-2,4-dione are a class of compounds derived thiazolidine. It is a 5-membered ring containing a sulfur atom and a nitrogen atom in positions 1 and 3, respectively, and carbonyl in position 4 and 2. Data in the literature demonstrate the synthetic thiaz

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Ubertone, Michele <1987&gt. "Il giudice e l'esperto: deferenza epistemica e deferenza semantica nel processo." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2019. http://amsdottorato.unibo.it/9118/5/Il%20giudice%20e%20l%27esperto.%20Deferenza%20epistemica%20e%20deferenza%20semantica%20nel%20processo.pdf.

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Esperti in materie diverse dal diritto stanno assumendo un ruolo sempre più importante nei sistemi giuridici contemporanei. Professionisti specializzati nelle più varie discipline (medici, ingegneri, chimici, urbanisti...) sono spesso tanto indispensabili quanto i giuristi per l’applicazione di molte disposizioni di legge. Ma come può il giudice servirsi del sapere tecnico degli esperti senza che questi usurpino il suo ruolo decisorio? Il giudice dovrebbe capire la deposizione dell’esperto prima di potersene servire? E se sì in che misura? Deve essere educato dall’esperto e acquisire da lui

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Stamford, Henrique da Silva Guerra Aline. "Estudo das Atividades Anti-inflamatória e Antinociceptiva dos Derivados Indol-imidazolidínicos 5-(1H-Indol-3-il-metileno)-2-tioxo-imidazolidin-4- ona (LPSF/NN-56) e 3-(4-Bromo-benzil)-5-(1H-indol-3-il-metileno)-2- tioxo-imidazolidin-4-ona(LPSF/NN-52)." Universidade Federal de Pernambuco, 2011. https://repositorio.ufpe.br/handle/123456789/9111.

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Made available in DSpace on 2014-06-12T23:13:13Z (GMT). No. of bitstreams: 2 arquivo2926_1.pdf: 1107682 bytes, checksum: 415c654211b59d782e8e45eded4938da (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) Previous issue date: 2011<br>Faculdade de Amparo à Ciência e Tecnologia do Estado de Pernambuco<br>A inflamação é uma resposta vital provocada por patógenos, danos físicos, isquemia, injúrias tóxicas ou auto-imunes com o objetivo de proteger o organismo. É um processo complexo, incluindo atividades de vários tipos de células e dezenas de mediadores protéicos

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De, Gregorio Davide. "Analisi elettromiografica durante il cammino: confronto di 5 algoritmi per la stima dell'attivazione muscolare del tibiale anteriore e del gastrocnemio." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2020. http://amslaurea.unibo.it/21366/.

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Lo studio del movimento umano è un ramo dell’ingegneria biomedica in forte espansione e di grande interesse sia dal punto di vista clinico-riabilitativo che dal punto di vista sportivo. I laboratori di analisi del movimento (LAM), in continua diffusione ed espansione, consentono la valutazione e l’analisi funzionale della deambulazione attraverso l’individuazione e l’osservazione di parametri cinematici, dinamici ed elettromiografici. La strumentazione contenuta in un LAM deve permettere la realizzazione di analisi multifattoriali ovvero deve consentire l’acquisizione in contemporanea d

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Lindberg, Carl. "Svensk uttagsbeskattnings förenlighet med etableringsfriheten : En analys av 22 kap. 5§ 4 pkt. och 7§ IL samt 17a kap. SBL." Thesis, Internationella Handelshögskolan, Högskolan i Jönköping, IHH, Rättsvetenskap, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-14429.

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The Swedish exit tax legislation in Chapter 22. § 5 p. 4 IL states that businesses who change its tax residence to another Member State within the EES are taxed as having its assets sold at the time of the change of domicile. This legislation was declared incompatible with the freedom of establishment in case RÅ 2009 ref. 30 due to the fact that businesses who changed tax residence were treated worse than businesses that remained within the Member State of origin. Of importance for the outcome of the case was the fact that ECJ had declared exit tax incompatible with the freedom of establishmen

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De, Wekker Lisvia. "Le nombre élevé d’heures de travail perturbe-t-il le rôle parental chez les parents d’enfants de 2-5 ans ?" Thesis, Université Laval, 2014. http://www.theses.ulaval.ca/2014/30776/30776.pdf.

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OBJECTIF: Évaluer l’association entre le nombre d’heures de travail des parents et leur rôle parental dans les familles d’enfants d’âge préscolaire qui ont fait partie de l’ELNEJ, 2004-2005. MÉTHODES : Le devis de l’étude est transversal. Le rôle parental a été mesuré par un instrument validé. Des analyses de régression linéaire ont été réalisées, en ajustant pour les facteurs de confusion potentiels. L’effet modifiant de plusieurs facteurs a été évalué. RÉSULTAT : Un nombre élevé d’heures de travail (40h et plus) n’était pas associé à un score parental plus faible, comparativement à un hora

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GOUVEIA, Allana Lemos Andrade. "Síntese, elucidação estrutural e avaliação da atividade biológica de novas 5-(indol-3-il-metileno)-4-tioxo-tiazolidin-2-onas." Universidade Federal de Pernambuco, 2015. https://repositorio.ufpe.br/handle/123456789/14959.

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Submitted by Haroudo Xavier Filho (haroudo.xavierfo@ufpe.br) on 2016-01-22T13:42:59Z No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) Dissertação Allanaa.pdf: 2503314 bytes, checksum: 4bf1facdbf4938006dc579126d83a52e (MD5)<br>Made available in DSpace on 2016-01-22T13:42:59Z (GMT). No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) Dissertação Allanaa.pdf: 2503314 bytes, checksum: 4bf1facdbf4938006dc579126d83a52e (MD5) Previous issue date: 2015-07-31<br>FACEPE<br>A leishmaniose visceral (LV) é uma doença

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Almeida, Leonardo Viana de. "Síntese e determinação da atividade antimicrobiana de 2-[5-nitro-tiofen-2-il]-3-acetil-5-[4-fenil-substituído]-2,3-diidro-1,3,4-oxadiazol frente à cepa ATCC 25923 de Staphylococcus aureus." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/9/9135/tde-07042010-131506/.

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A introdução de um grupo substituinte na molécula de um fármaco promove alterações químico-estruturais que, por sua vez, modificam suas propriedades físicoquímicas. O arranjo espacial de átomos ou grupos de átomos, em especial grupos funcionais, na molécula de um fármaco, expressos por meio de suas propriedades físico-químicas, influenciam direta ou indiretamente na interação fármaco-receptor. Esta, por sua vez, determina aspectos farmacológicos e farmacocinéticos que influem na eficácia terapêutica do medicamento. Assim, uma série de compostos 2-[5-nitro-tiofen-2-il]-3-acetil-5-[4-fenil-subst

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Jaime, Bezerra Mendonça Junior Francisco. "Síntese de Glicopiranosídeos 2,3 - insaturados acoplados a heterociclos em C-4. Funcionalização da posição C-5 de glicoheterociclos 4 (5 halo uracil l il) através de reações catalisadas por Pd (0)." Universidade Federal de Pernambuco, 2005. https://repositorio.ufpe.br/handle/123456789/2136.

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Made available in DSpace on 2014-06-12T15:54:49Z (GMT). No. of bitstreams: 2 arquivo5250_1.pdf: 2079339 bytes, checksum: e9e25a54bf34a791ec9cd207a86bb39d (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) Previous issue date: 2005<br>Reações catalíticas promovidas por paládio(0) têm sido utilizadas nos últimos anos com sucesso para diversas reações de acoplamento entre carboidratos e bases nitrogenadas como nucleófilos para síntese de nucleosídeos e nucleotídeos com pronunciadas propriedades antivirais e anticancerígenas. Nos últimos 20 anos, paládio(0) também

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Wolf, Lucas. "Síntese de heterociclos: 2-alquil/arilcalcogeno-n-(4-aril-1,3-tiazol-2-il)acetamidas e (s)-n-(1-(3-aril-1,2,4-oxadiazol-5-il)alquil)-2-(calcogenofenil) acetamidas derivados de organocalcogênios." Universidade Federal de Santa Maria, 2015. http://repositorio.ufsm.br/handle/1/4271.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>In the present work, a series of 2-alkyl/arylchalcogenide-N-(4-aryl-1,3-thiazol-2-yl)acetamide was prepared via addition of aryl or alkyl chalcogenides. This methodology allowed the preparation of new derivatives of 2-amino-1,3-thiazoles in good yields. The compound synthesized is intended to evaluate the biological potential from the antioxidant activity by scavenging capacity of the assay by ABTS and DPPH. Was also developed a methodology for obtaining the compounds (S)-N-(alkyl-1-(3-aryl-1,2,4-oxadiazol-5-yl)-2-(phenylchalcogeni

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Woschnagg, Charlotte. "The oxidative metabolism by eosinophils : Effects of allergen exposure and interleukin-5." Doctoral thesis, Uppsala University, Department of Medical Sciences, 2000. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-514.

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<p>In this thesis the oxidative metabolism by blood eosinophils from birch pollen allergic subjects was studied and compared to that by eosinophils from healthy controls, during and out of the pollen season. The effects and mechanisms of <i>in vitro</i> IL-5 priming on blood eosinophils were investigated and compared to the effects of <i>in vivo</i> priming during pollen exposure.</p><p>The main findings of this work were that the oxidative metabolism by blood eosinophils taken from pollen allergic subjects is reduced during the pollen season. The eosinophils taken from asymptomatic allergics

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Reyes, Zelayarán Joan Manuel. "Determinación de la expresión de los genes de IgA y citoquinas asociadas IL-5, IL-6 Y TGF-Β en mucosa intestinal de crías de alpacas (Vicugna pacos) vacunadas con antígeno clostridial". Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2015. https://hdl.handle.net/20.500.12672/5764.

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Determina y compara los niveles de expresión de los genes de IgA y citoquinas asociadas IL-5, IL-6 y TGF-β en la mucosa intestinal de crías de alpaca clínicamente sanas, las cuales recibieron una vacuna oral de antígeno clostridial en dos dosis.<br>Tesis

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Jenkins, Brendan John. "Activating point mutations in the common ?gb?s[beta]-subunit of the human GM-CSF, IL-3 and IL-5 receptors : implications for receptor function and role in disease / by Brendan John Jenkins." Title page, contents and summary only, 1998. http://web4.library.adelaide.edu.au/theses/09PH/09phj518.pdf.

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Granlund, Annelie, and Ida Karlsson. "Avdragsförbudet för valutakursförluster på näringsbetingade andelar i 25 a kap. 5 § IL : I strid med etableringsfriheten och den fria rörligheten för kaptial?" Thesis, Internationella Handelshögskolan, Högskolan i Jönköping, IHH, Redovisning och Rättsvetenskap, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-26617.

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En valutakursförlust som uppstår till följd av att ett bolag avyttrar näringsbetingade andelar i ett utländskt dotterbolag är enligt svensk gällande rätt inte avdragsgill, vilket följer av 25 a kap. 5 § IL. Det råder oklarhet om huruvida det svenska avdragsförbudet för valutakursförluster på näringsbetingade andelar i utländska dotterbolag strider mot EU-rättens etableringsfrihet och fria rörlighet för kapital. Oklarheterna uppstår på grund av att det inte är tydligt vad som anses hindrande mot en EU-frihet och hur detta bedöms. Det har anförts att hinder anses föreligga om en medlemsstats nat

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Costantini, Tommaso <1995&gt. ""Financial Fair Play ed equilibrio competitivo: come la nuova normativa UEFA ha modificato il livello di competitività nei 5 maggiori campionati europei"." Master's Degree Thesis, Università Ca' Foscari Venezia, 2021. http://hdl.handle.net/10579/19371.

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L'elaborato, partendo da una descrizione generale del fenomeno "calcio" e, nello specifico, della sua evoluzione da gioco a sport. Analizzando varie tematiche ruotanti attorno al business del calcio, pone quale obiettivo principale quello di rispondere ad una specifica domanda: il Fair Play Finanziario ha ridotto o aumentato le disparità competitive tra i club? Dando una descrizione generale del mondo del pallone, passa da ambiti generali ad altri più specifici, quali ad esempio le voci più rilevanti interne ai bilanci delle società sportive, analizzandone alcune nello specifico. Vengono enun

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