Relevant bibliographies by topics / IL-7 receptor alpha

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Conference papers

Academic literature on the topic 'IL-7 receptor alpha'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'IL-7 receptor alpha.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "IL-7 receptor alpha"

1

Fahlman, C., FW Jacobsen, OP Veiby, IK McNiece, HK Blomhoff, and SE Jacobsen. "Tumor necrosis factor-alpha (TNF-alpha) potently enhances in vitro macrophage production from primitive murine hematopoietic progenitor cells in combination with stem cell factor and interleukin-7: novel stimulatory role of p55 TNF receptors." Blood 84, no. 5 (1994): 1528–33. http://dx.doi.org/10.1182/blood.v84.5.1528.1528.

Full text
Abstract:
Abstract Tumor necrosis factor-alpha (TNF-alpha) is a bifunctional regulator of hematopoiesis, and its cellular responses are mediated by two distinct cell surface receptors. TNF-alpha generally inhibits the growth of primitive murine hematopoietic progenitor cells (Lin-Scal+) in response to multiple cytokine combinations, and the p75 TNF receptor is essential in signaling such inhibition. In the present study we show the reverse phenomenon in that TNF-alpha on the same progenitor cell population in combination with stem cell factor (SCF) and interleukin-7 (IL-7) through the p55 TNF receptor c
APA, Harvard, Vancouver, ISO, and other styles
2

Fahlman, C., FW Jacobsen, OP Veiby, IK McNiece, HK Blomhoff, and SE Jacobsen. "Tumor necrosis factor-alpha (TNF-alpha) potently enhances in vitro macrophage production from primitive murine hematopoietic progenitor cells in combination with stem cell factor and interleukin-7: novel stimulatory role of p55 TNF receptors." Blood 84, no. 5 (1994): 1528–33. http://dx.doi.org/10.1182/blood.v84.5.1528.bloodjournal8451528.

Full text
Abstract:
Tumor necrosis factor-alpha (TNF-alpha) is a bifunctional regulator of hematopoiesis, and its cellular responses are mediated by two distinct cell surface receptors. TNF-alpha generally inhibits the growth of primitive murine hematopoietic progenitor cells (Lin-Scal+) in response to multiple cytokine combinations, and the p75 TNF receptor is essential in signaling such inhibition. In the present study we show the reverse phenomenon in that TNF-alpha on the same progenitor cell population in combination with stem cell factor (SCF) and interleukin-7 (IL-7) through the p55 TNF receptor can recrui
APA, Harvard, Vancouver, ISO, and other styles
3

SON, Min-Young, Kwang-Min CHOI, Min-Soo JOO та Chan-Il PARK. "Molecular Characterization and Expression Analysis of the Interleukin 7 Receptor Alpha Chain (IL-7Rα) Gene from Red Sea Bream (Pagrus major)". JOURNAL OF FISHRIES AND MARINE SCIENCES EDUCATION 32, № 2 (2020): 560–69. http://dx.doi.org/10.13000/jfmse.2020.4.32.2.560.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Sanyal, Mrinmoy, Kira Y. Dionis, Alireza Baradaran-Heravi, et al. "Lack of IL-7 Receptor Alpha Chain (CD127) Expression In T Cells Is a Hallmark of T-Cell Immunodeficiency In Schimke Immuno-Osseous Dysplasia (SIOD)." Blood 116, no. 21 (2010): 2767. http://dx.doi.org/10.1182/blood.v116.21.2767.2767.

Full text
Abstract:
Abstract Abstract 2767 Schimke immuno-osseous dysplasia (SIOD) is an autosomal recessive, incompletely penetrant, childhood disorder associated with biallelic loss-of-function mutations of SMARCAL1 (swi/snf-related matrix-associated actin-dependent regulator of chromatin, subfamily-a-like-1) gene. The SMARCAL1 gene encodes for the DNA annealing helicase although it is unknown why this impairment results in skeletal dysplasia, renal dysfunction, and T-cell lymphopenia. The representation of T-cell subsets in SIOD patients is further characterized by a high proportion of memory (CD45RA−CD45RO+)
APA, Harvard, Vancouver, ISO, and other styles
5

He, Y. W., and T. R. Malek. "Interleukin-7 receptor alpha is essential for the development of gamma delta + T cells, but not natural killer cells." Journal of Experimental Medicine 184, no. 1 (1996): 289–93. http://dx.doi.org/10.1084/jem.184.1.289.

Full text
Abstract:
Mice that lack a functional gamma c subunit of the receptors for interleukin (IL)-2, IL-4, IL-7, IL-9, and IL-15 display profound defects in lymphoid development. The IL-7/IL-7R system represents a critical interaction for conventional T and B cell development. In this report, the role of IL-7R alpha in the development of lymphoid lineages other than conventional T and B cells was examined. We demonstrate that gamma delta + T cells were absent in IL-7R alpha-deficient mice, whereas the development and function of natural killer cells were normal. Thus, IL-7R alpha function is required for the
APA, Harvard, Vancouver, ISO, and other styles
6

Kawahara, A., Y. Minami, and T. Taniguchi. "Evidence for a critical role for the cytoplasmic region of the interleukin 2 (IL-2) receptor gamma chain in IL-2, IL-4, and IL-7 signalling." Molecular and Cellular Biology 14, no. 8 (1994): 5433–40. http://dx.doi.org/10.1128/mcb.14.8.5433.

Full text
Abstract:
The high-affinity interleukin 2 receptor (IL-2R) consists of at least three distinct subunits: the IL-2R alpha chain (IL-2R alpha), beta chain (IL-2R beta), and gamma chain (IL-2R gamma). It has been shown that the cytoplasmic region of IL-2R beta, but not of IL-2R alpha, is essential for IL-2 signalling to the cell interior. In the present study, we examined the functional role of the IL-2R gamma cytoplasmic region in the IL-3-dependent mouse hematopoietic cell line BAF-B03, which expresses the endogenous IL-2R alpha and IL-2R gamma, or its subline F7, which additionally expresses human IL-2R
APA, Harvard, Vancouver, ISO, and other styles
7

Kawahara, A., Y. Minami, and T. Taniguchi. "Evidence for a critical role for the cytoplasmic region of the interleukin 2 (IL-2) receptor gamma chain in IL-2, IL-4, and IL-7 signalling." Molecular and Cellular Biology 14, no. 8 (1994): 5433–40. http://dx.doi.org/10.1128/mcb.14.8.5433-5440.1994.

Full text
Abstract:
The high-affinity interleukin 2 receptor (IL-2R) consists of at least three distinct subunits: the IL-2R alpha chain (IL-2R alpha), beta chain (IL-2R beta), and gamma chain (IL-2R gamma). It has been shown that the cytoplasmic region of IL-2R beta, but not of IL-2R alpha, is essential for IL-2 signalling to the cell interior. In the present study, we examined the functional role of the IL-2R gamma cytoplasmic region in the IL-3-dependent mouse hematopoietic cell line BAF-B03, which expresses the endogenous IL-2R alpha and IL-2R gamma, or its subline F7, which additionally expresses human IL-2R
APA, Harvard, Vancouver, ISO, and other styles
8

Marsh, C. B., S. A. Moore, H. A. Pope, and M. D. Wewers. "IL-1ra suppresses endotoxin-induced IL-1 beta and TNF-alpha release from mononuclear phagocytes." American Journal of Physiology-Lung Cellular and Molecular Physiology 267, no. 1 (1994): L39—L45. http://dx.doi.org/10.1152/ajplung.1994.267.1.l39.

Full text
Abstract:
The proinflammatory effects of lipopolysaccharide (LPS) are modulated in large part through the induction of interleukin-1 beta (IL-1 beta) and tumor necrosis factor-alpha (TNF-alpha) release by mononuclear phagocytes. However, IL-1's target cell effects can be suppressed by IL-1 receptor agonist (IL-1ra). Because mononuclear phagocytes produce and respond to IL-1 via IL-1 receptors, we hypothesized that IL-1ra may also be able to block receptors on IL-1 producer cells and inhibit secondary IL-1-induced IL-1 production. To test this hypothesis, mononuclear cells and alveolar macrophages were s
APA, Harvard, Vancouver, ISO, and other styles
9

Hara, T., M. Ichihara, M. Takagi, and A. Miyajima. "Interleukin-3 (IL-3) poor-responsive inbred mouse strains carry the identical deletion of a branch point in the IL-3 receptor alpha subunit gene." Blood 85, no. 9 (1995): 2331–36. http://dx.doi.org/10.1182/blood.v85.9.2331.bloodjournal8592331.

Full text
Abstract:
Interleukin-3 (IL-3) stimulates colony formation of multiple lineages of hematopoietic cells. Bone marrow cells of A/J mice are nonresponsive to IL-3, and this observation has recently been correlated with aberrant mRNA splicing and impaired expression of the IL-3 receptor alpha subunit (IL-3R alpha), a binding component of the high-affinity receptors. We examined the IL-3R alpha gene in 27 inbred mouse strains and found the identical mutation, a 5-bp deletion at the branch point of intron 7, in 10 of these mouse strains. Bone marrow cells isolated from these 10 mouse strains did not express I
APA, Harvard, Vancouver, ISO, and other styles
10

Plum, J., M. De Smedt, G. Leclercq, B. Verhasselt, and B. Vandekerckhove. "Interleukin-7 is a critical growth factor in early human T-cell development." Blood 88, no. 11 (1996): 4239–45. http://dx.doi.org/10.1182/blood.v88.11.4239.bloodjournal88114239.

Full text
Abstract:
Highly purified human CD34+ fetal liver stem cells differentiate to mature T cells when seeded in vitro into isolated fetal thymic lobes of severe combined immunodeficient (SCID) mice followed by fetal thymus organ culture (FTOC). Here, this chimeric human-mouse FTOC was used to address the role of interleukin-7 (IL-7) and of the alpha chain of the IL-7 receptor (IL-7R alpha) in early human T-cell development. We report that addition of either the monoclonal antibody (MoAb) M25, which neutralizes both human and mouse IL-7, or the MoAb M21, which recognizes and blocks exclusively the human high
APA, Harvard, Vancouver, ISO, and other styles
More sources

Dissertations / Theses on the topic "IL-7 receptor alpha"

1

Al-Ghazawi, Feras. "Understanding the Mechanisms by which Interleukin (IL)-7 Down-Regulates Expression of the IL-7 Receptor Alpha-Chain (CD127) in Human CD8 T Cells." Thesis, Université d'Ottawa / University of Ottawa, 2013. http://hdl.handle.net/10393/24355.

Full text
Abstract:
Interleukin (IL)-7 is an essential non-redundant cytokine and throughout the life-span of a T cell signaling via the IL-7 receptor influences cell survival, proliferation and function. It is therefore no surprise that expression of the IL-7 receptor alpha-chain (CD127) is tightly regulated. In this study I establish IL-7 down regulates CD127 gene transcription and surface protein expression in primary human CD8 T cells through two mechanisms. Upon binding IL-7, surface CD127 is rapidly internalized and phosphorylated at the critical tyrosine residue Y449. Concurrent activation of the JAK/STAT5
APA, Harvard, Vancouver, ISO, and other styles
2

Henriques, Catarina Martins de Oliveira 1983. "The regulation of interleukin 7 receptor alpha internalization, recycling and degradation by IL-7:-possible implications in T-cell homeostasis, migration and." Doctoral thesis, 2009. http://hdl.handle.net/10451/6501.

Full text
Abstract:
Tese de doutoramento, Ciências Biomédica (Ciências Biopatológicas), Universidade de Lisboa, Faculdade de Medicina, 2010<br>Although leukaemia arises in the bone marrow, patients often present infiltration of other organs, such as the spleen, CNS, liver, lungs and peripheral blood. Mechanisms of cell migration, invasion, vasculogenesis and angiogenesis have been shown to play a crucial role in haematological cancers. Moreover, micro-environmental factors such as chemokines and cytokines were already shown to enhance T-cell acute lymphoblastic leukaemia (T-ALL) viability, proliferation and migra
APA, Harvard, Vancouver, ISO, and other styles
3

Lawson, Maxx. "Modulating the T cell response: using anti-interleukin-7 receptor-alpha monoclonal antibodies with autoantigen-specific immunotherapy to prevent type-1-diabetes." Thesis, 2019. https://hdl.handle.net/2144/37107.

Full text
Abstract:
Autoimmunity develops over an extended period of time as the result of an amalgamation of genetic, environmental, and immunologic events. Though the precise etiological factors leading to most autoimmune disease are awaiting consensus, a common thread of the autoimmune paradigm is the inappropriate activation of tissue-specific immune cells by one or more autoantigen, which begins the destruction of the tissue. To prohibit immunopathology and fine-tune the immune responses in healthy individuals, the stimulatory activities of effector/memory T (Teffs) cells must be counteracted by the suppress
APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "IL-7 receptor alpha"

1

Sobus, Samantha L., Michelle A. Romano, Janelle Mackowiak, and Graham W. Warren. "Abstract 3456: Nicotine and the alpha-7 nicotinic acetylcholine receptor in the regulation of response to radiotherapy." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-3456.

Full text
APA, Harvard, Vancouver, ISO, and other styles
You might also be interested in the extended bibliographies on the topic 'IL-7 receptor alpha' for particular source types:
Journal articles
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography