Academic literature on the topic 'Imidazole; Benzothiazole and Antibacterial and Antifungal activities'

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Journal articles on the topic "Imidazole; Benzothiazole and Antibacterial and Antifungal activities"

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Purvesh, J. Shah. "Preparation, Characterization and Biological Screening of Novel Imidazoles." Journal of Progressive Research in Chemistry 2, no. 1 (2015): 54–60. https://doi.org/10.5281/zenodo.3970044.

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The 4-benzylidene-2-(4-methoxyphenyl)oxazol-5(4H)-one (B) has been prepared from cyclo condensation reaction between hippuric acid (A) with p-anisaldehyde. A series of 4-benzylidene-1-(substitued-2- benzothiazolyl)-2-(4-methoxyphenyl)-1H-imidazol-5(4H)-one (D1-6) have been synthesized from 2-amino substituted benzothiazole (C1-6) by condensation reaction with 4-benzylidene-2-(4-methoxyphenyl) oxazol-5(4H)-one (B). The synthesized compounds were characterized by IR, 1H-NMR, 13C-NMR and Mass spectral data. All the compounds were screened for their antibacterial and antifungal activities.
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Rawat, Bhupender Singh, and S. C. Mehra. "SYNTHESIS OF SOME NEW 1, 3-DI METHYL SUBSTITUTED GUANIDINE WITH POSSIBLE ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY." Green Chemistry & Technology Letters 2, no. 3 (2016): 138–40. http://dx.doi.org/10.18510/gctl.2016.233.

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The compounds containing thiazole, thiadiazole, oxazole, oxadiazole, imidazole, pyrimidine, pyridine & benzothiazole rings have been found to exhibit broad spectrum of biological activities.Derivatives of 1, 2, 4-thiadiazole and 1, 2, 4-thiadiazolidines exhibit antibacterial and antifungal activity1. Thiazolyl guanidines2 and various substituted aryl guanidine’s have been found to exhibit antibacterial & antifungal activities3.Keeping all these views in mind attempts were made to synthesized some new 1,3-di methyl Substituted Guanidine.In the present work 2,4 Dimethyl -3,5-(di Aryl imi
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Baldaniya, B. B. "Synthesis, Characterization and Biological Activity of 5-Arylidene-3-(6,7-dicloro-1,3-benzothiazol-2-yl)-phenyl-3,5-dihydro-4H-imidazol-4-ones." E-Journal of Chemistry 7, no. 1 (2010): 81–84. http://dx.doi.org/10.1155/2010/264036.

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Some novel 5-arylidene-3-(6,7-dichloro-1,3-benzothiazol-2-yl)-2-phenyl-3,5-dihydro-4H-imidazol-4-ones (6a-q)have been synthesized and characterized by elemental analyses, IR, NMR, and mass spectra. The products have been evaluated for antibacterial and antifungal activities against different strains of bacteria and fungi.
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Eriamiatoe, I. O., B. J. Owolabi, V. Mzozoyana, H. C. Ndibe, and T. Eriamiatoe. "The Potential Antifungal and Antibacterial of 5- Chloro-1- Methyl- 4- Nitroimidazole." International Journal of Research and Scientific Innovation XI, no. VII (2024): 366–72. http://dx.doi.org/10.51244/ijrsi.2024.1107027.

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Imidazole is a nitrogen-containing heterocyclic ring that possesses biological and pharmaceutical importance. The imidazole ring is a constituent of several important natural products, including purine, histamine, histidine, and nucleic acid, while the nitroimidazole and its derivatives possess an extensive spectrum of biological activities such as antibacterial, anticancer, antitubercular, antifungal, analgesic, and anti-HIV activities. This paper aims to evaluate the in vitro antifungal and antibacterial activities of 5-chloro-1-methyl-4-nitroimidazole. The synthesis of this compound was car
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Morsy, Mohamed A., Enas M. Ali, Mahmoud Kandeel, et al. "Screening and Molecular Docking of Novel Benzothiazole Derivatives as Potential Antimicrobial Agents." Antibiotics 9, no. 5 (2020): 221. http://dx.doi.org/10.3390/antibiotics9050221.

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The burden of antibiotic resistance necessitates a continued search for new antimicrobials. We evaluated the antimicrobial activities of novel benzothiazoles synthesized by our group. Antibacterial activity was evaluated in vitro in Staphylococcus aureus, Bacillus subtilis, and Escherichia coli, while the antifungal activity was tested in Candida albicans and Aspergillus niger, and expressed as the minimum inhibitory concentration (MIC; µg/mL). MIC values of benzothiazole compounds ranged from 25 to 200 µg/mL. Compounds 3 and 4 gave high antibacterial and moderate antifungal activities, while
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Jasiewicz, Beata, Karolina Babijczuk, Beata Warżajtis, et al. "Indole Derivatives Bearing Imidazole, Benzothiazole-2-Thione or Benzoxazole-2-Thione Moieties—Synthesis, Structure and Evaluation of Their Cytoprotective, Antioxidant, Antibacterial and Fungicidal Activities." Molecules 28, no. 2 (2023): 708. http://dx.doi.org/10.3390/molecules28020708.

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In the search for new bioactive compounds, a methodology based on combining two molecules with biological properties into a new hybrid molecule was used to design and synthesize of a series of ten indole derivatives bearing imidazole, benzothiazole-2-thione, or benzoxazole-2-thione moieties at the C-3 position. The compounds were spectroscopically characterized and tested for their antioxidant, antibacterial, and fungicidal activities. The crystal structures were determined for five of them. Comparison of the closely related structures containing either benzothiazole-2-thione or benzoxazole-2-
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ZOMORODIAN, K., S. KHABNADIDEH, L. ZAMANI, K. PAKSHIR, and M. TAJADDOD. "EVALUATION OF ANTIFUNGAL AND ANTIBACTERIAL ACTIVITY OF SOME NEW BENZIMIDAZOLE DERIVATIVES." Latin American Applied Research - An international journal 48, no. 2 (2018): 125–29. http://dx.doi.org/10.52292/j.laar.2018.270.

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The extensive use of antifungal drugs and their resistance against fungal infections have led to discover new antimicrobial compounds. We previously described synthesis of some new derivatives of 2-methylbenzimidazole (1a-5a) and 5,6dimethylbenzimidazol (1b-5b). Here we evaluated the antimicrobial activities of these compounds against different species of micro organisms including gram positive and gram negative bacteria as well as fungi. Broth micro-dilution method as recommended by clinical and laboratory standard institute (CLSI) was used for this purpose. The results show compounds 2-Methy
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Duong Quoc, Hoan, Du Nguyen Duc, Luong Truong Minh, Thao Nguyen Thi Thach, and Hien Nguyen Thi Thu. "SYNTHESIS OF SOME BENZOTHIAZOLE ANILINE DERIVATIVES AND THEIR BIOLOGICAL ACTIVITIES." Journal of Science Natural Science 67, no. 3 (2022): 68–74. http://dx.doi.org/10.18173/2354-1059.2022-0042.

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Three benzothiazole aniline derivatives 2a, 2b, and 2c were synthesized successfully by the reduction reaction of the respective nitro compound in neutral condition with Na2S2O4 in moderate yield. Structures of these derivatives were elucidated by IR, NMR, and MS analysis that referred to a strong agreement between spectral data and structures. Three compounds 2a, 2b, and 2c showed weak antioxidant, antibacterial and antifungal activities.
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Vaishnavi P. Bansod, Vinayak A. Katekar, and Swati Deshmukh. "A review: Synthesis characterization and in vitro anti-mycobacterial activity of some novel benzothiazole." GSC Biological and Pharmaceutical Sciences 25, no. 2 (2023): 169–79. http://dx.doi.org/10.30574/gscbps.2023.25.2.0433.

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Heterocyclic compounds, analogs, and derivatives have received a lot of interest recently because of their advantageous biological and pharmacological properties. Flexible substrates include the heterocyclic compounds that benzothiazole and its analogs can be used to synthesize. The benzothiazole nucleus is utilized to create a wide variety of pharmaceuticals. The biological activity of benzothiazole derivatives has recently undergone some intriguing alterations. These compounds stand out in the world of medicinal chemistry due to their high pharmacological potential. According to the World He
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Vaishnavi, P. Bansod, A. Katekar Vinayak, and Deshmukh Swati. "A review: Synthesis characterization and in vitro anti-mycobacterial activity of some novel benzothiazole." GSC Biological and Pharmaceutical Sciences 25, no. 2 (2023): 169–79. https://doi.org/10.5281/zenodo.10609199.

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Heterocyclic compounds, analogs, and derivatives have received a lot of interest recently because of their advantageous biological and pharmacological properties. Flexible substrates include the heterocyclic compounds that benzothiazole and its analogs can be used to synthesize. The benzothiazole nucleus is utilized to create a wide variety of pharmaceuticals. The biological activity of benzothiazole derivatives has recently undergone some intriguing alterations. These compounds stand out in the world of medicinal chemistry due to their high pharmacological potential. According to the World He
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Book chapters on the topic "Imidazole; Benzothiazole and Antibacterial and Antifungal activities"

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Thatikayala, Mahender, Anil Kumar Garige, and Hemalatha Gadegoni. "Benzimidazole: Pharmacological Profile." In Benzimidazole [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.102091.

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Benzimidazole is a bicyclic heterocyclic aromatic compound in which benzene fused to imidazole moiety. Benzimidazole holds a vital role in the field of medicinal chemistry which possesses wide variety of pharmacological activities like antibacterial, anti cancer, antifungal, antileishmanial, anti tubercular, anti viral and anti malarial respectively, hence the benzimidazole moiety attracting the medicinal chemist to synthesize the different benzimidazole derivatives with wide variety of pharmacological activities. The book chapter mainly discussed the anti cancer, anti HIV, antileishmanial and
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