Academic literature on the topic 'Imipramine and antioxidant'

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Journal articles on the topic "Imipramine and antioxidant"

1

Chang, Geng-Ruei, Po-Hsun Hou, Chao-Min Wang, et al. "Imipramine Accelerates Nonalcoholic Fatty Liver Disease, Renal Impairment, Diabetic Retinopathy, Insulin Resistance, and Urinary Chromium Loss in Obese Mice." Veterinary Sciences 8, no. 9 (2021): 189. http://dx.doi.org/10.3390/vetsci8090189.

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Imipramine is a tricyclic antidepressant that has been approved for treating depression and anxiety in patients and animals and that has relatively mild side effects. However, the mechanisms of imipramine-associated disruption to metabolism and negative hepatic, renal, and retinal effects are not well defined. In this study, we evaluated C57BL6/J mice subjected to a high-fat diet (HFD) to study imipramine’s influences on obesity, fatty liver scores, glucose homeostasis, hepatic damage, distribution of chromium, and retinal/renal impairments. Obese mice receiving imipramine treatment had higher
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2

Réus, Gislaine Z., Roberto B. Stringari, Bruna de Souza, et al. "Harmine and Imipramine Promote Antioxidant Activities in Prefrontal Cortex and Hippocampus." Oxidative Medicine and Cellular Longevity 3, no. 5 (2010): 325–31. http://dx.doi.org/10.4161/oxim.3.5.13109.

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A growing body of evidence has suggested that reactive oxygen species (ROS) may play an important role in the physiopathology of depression. Evidence has pointed to the β-carboline harmine as a potential therapeutic target for the treatment of depression. The present study we evaluated the effects of acute and chronic administration of harmine (5, 10 and 15 mg/kg) and imipramine (10, 20 and 30 mg/kg) or saline in lipid and protein oxidation levels and superoxide dismutase (SOD) and catalase (CAT) activities in rat prefrontal cortex and hippocampus. Acute and chronic treatments with imipramine
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3

Hadjimitova, Vera, Trayko Traykov, Milka Mileva, and Stefan Ribarov. "Effect of Some Psychotropic Drugs on Luminol - Dependent Chemiluminescence Induced by O2–, •OH, HOCl." Zeitschrift für Naturforschung C 57, no. 11-12 (2002): 1066–71. http://dx.doi.org/10.1515/znc-2002-11-1220.

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We studied antioxidant activity of six neuroleptics (chlorpromazine, levomepromazine, promethazine, trifluoperazine and thioridazine) and two antidepressants (imipramine and amitriptyline) in the range of concentration of 10−7−10−4 м. We applied luminol-dependent chemiluminescence to test the ability of these drugs to scavenge the biologically relevant oxygen-derived species: hydroxyl radical, superoxide radical, hypochlorous acid in vitro. We found that the phenothiazines were powerful scavengers of hydroxyl and superoxide radicals. Chlorprothixene, amitriptyline and imipramine had no scaveng
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Mohan, Gaanappriya, and Amala Kesavan. "Dose-dependent anxiolytic and antioxidant efficacy of Piper betle." BIOINFOLET - A Quarterly Journal of Life Sciences 22, no. 2 (2025): 229–33. https://doi.org/10.5958/0976-4755.2025.00114.9.

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Present study was undertaken to investigate anxiolytic and antioxidant properties of a methanolic extract of Piper betle Linn. leaves in female Wistar rats subjected to Chronic Unpredictable Mild Stress (CUMS). Two doses (100 and 200 mg/kg) of the extract were administered orally and compared with imipramine – a standard anxiolytic agent. Behavioral assessments using the Elevated Plus Maze (EPM) indicated that the dose of 100 mg/kg body weight notably increased the transfer latency and decreased the time spent in the closed arms, signifying anxiolytic activity similar to that of imipramine. Co
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Parikshit, V. Choudhari, G. Kanse Vanita, Venkatachalam A., and R. Pal Punam. "Antidepressant and nootropic activity of aqueous extract of Bougainvillea glabra." World Journal of Advanced Research and Reviews 10, no. 1 (2021): 334–39. https://doi.org/10.5281/zenodo.4734597.

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The aim of this analysis was to assess antidepressant & nootropic capacity of Bougainvillea Glabra aqueous extract (BGAE). Forced swim test, tail suspension test, & tetrabenazine mediated catalepsy & ptosis models were used to assess BGAE's antidepressant efficacy in mice at doses of 250 & 500 mg/kg orally. Morris water maze with elevated plus maze (EPM) was used to test nootropic behaviour. Normal medications for antidepressant & nootropic function were imipramine (25 mg/kg) & piracetam (300 mg/kg), respectively. Antioxidant assays such as DPPH & TBARS were use
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6

Sinharoy, Debalina, Debanjan Mukhopadhyay, Shauroseni Palchoudhuri, Bidisha Ghosh, Sukhen Das, and Sujata G. Dastidar. "Distinct Antioxidant Activity of a Common Antidepressant Drug Imipramine." Free Radicals and Antioxidants 6, no. 2 (2016): 151–54. http://dx.doi.org/10.5530/fra.2016.2.4.

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Parikshit V. Choudhari, Vanita G. Kanse, A. Venkatachalam, and Punam R. Pal. "Antidepressant and nootropic activity of aqueous extract of Bougainvillea glabra." World Journal of Advanced Research and Reviews 10, no. 1 (2021): 334–39. http://dx.doi.org/10.30574/wjarr.2021.10.1.0163.

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The aim of this analysis was to assess antidepressant & nootropic capacity of Bougainvillea Glabra aqueous extract (BGAE). Forced swim test, tail suspension test, & tetrabenazine mediated catalepsy & ptosis models were used to assess BGAE's antidepressant efficacy in mice at doses of 250 & 500 mg/kg orally. Morris water maze with elevated plus maze (EPM) was used to test nootropic behaviour. Normal medications for antidepressant & nootropic function were imipramine (25 mg/kg) & piracetam (300 mg/kg), respectively. Antioxidant assays such as DPPH & TBARS were used to
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8

Todirascu-Ciornea, Elena, Heba A. S. El-Nashar, Nada M. Mostafa, et al. "Schinus terebinthifolius Essential Oil Attenuates Scopolamine-Induced Memory Deficits via Cholinergic Modulation and Antioxidant Properties in a Zebrafish Model." Evidence-Based Complementary and Alternative Medicine 2019 (December 2, 2019): 1–11. http://dx.doi.org/10.1155/2019/5256781.

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Schinus terebinthifolius is a plant well recognized for its therapeutic profile such as anti-inflammatory and antitumor activities, promoting antibacterial activity and antioxidant and antidiabetic properties. This study aimed at examining whether Schinus terebinthifolius memory-enhancing activities are mediated by cholinergic and brain antioxidant systems in a scopolamine zebrafish model. Schinus terebinthifolius essential oil (10, 25, and 50 μL/L) was delivered to zebrafish by immersion in water for 8 days. Memory deficits were induced by scopolamine (100 μM) administration. Zebrafish were d
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Choudhury Barua, Chandana, Lipika Buragohain, Farida Rahman, Ramakrishna Elancheran, and Hooriyah Rizavi. "Zanthoxylum Alatum Attenuates Chronic Restraint Stress Adverse Behavioral Effects Via the Mitigation of Oxidative Stress and Modulating the Expression of Genes Involved in Endoplasmic Reticulum Stress in Mice." Basic and Clinical Neuroscience Journal 13, no. 5 (2022): 647–60. http://dx.doi.org/10.32598/bcn.2022.1477.1.

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Introduction: The functions of the endoplasmic reticulum (ER) are important, particularly in the proteins’ synthesis, folding, modification, and transport. Based on traditional medicine and our previous studies on Zanthoxylum alatum in lipopolysaccharide-induced depressive behavior and scopolamine-induced impaired memory, the present study explored the role of hydroalcoholic extract of Z. alatum (ZAHA) seeds in reducing the ER stress in mice. Methods: The mice were restrained for 28 days in polystyrene tubes. ZAHA (100 and 200 mg/kg, PO) and imipramine (10 mg/kg, IP) were administered daily, 4
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Asadi, Kosar, Saeid Abbasi-Maleki, and Goudarz Sadeghi Hashjin. "Antidepressant-like effect of Cuminum cyminum essential oil on the forced swim and tail suspension tests in male mice." Journal of Shahrekord University of Medical Sciences 22, no. 4 (2020): 167–72. http://dx.doi.org/10.34172/jsums.2020.27.

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Background and aims: Several pharmacological and biological activities have been attributed to Cuminum cyminum L. (CC), including analgesic, antioxidant, anti-inflammatory, and anti-epileptic effects. In this regard, the present study evaluated the antidepressant-like effects of the CC essential oil (EO) on the forced swim test (FST) and tail suspension test (TST) in male mice. Materials and Methods: The gas chromatography-mass spectrometry (GC-MS) apparatus was used for detecting the chemical compounds of CC EO. In the present study, 72 male NMRI mice were randomly allocated to 12 groups (eac
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