Relevant bibliographies by topics / In situ injectable implant

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'In situ injectable implant'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "In situ injectable implant"

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Christian, Ruby, Vaishali Thakkar, Tushar Patel, et al. "Development of Biodegradable Injectable In situ Forming Implants for Sustained Release of Lornoxicam." Current Drug Delivery 16, no. 1 (2018): 66–78. http://dx.doi.org/10.2174/1567201815666180927155710.

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Objective: The focus of this study was to develop in situ injectable implants of Lornoxicam which could provide sustained drug release. Methods: Biodegradable in situ injectable implants were prepared by polymer precipitation method using polylactide-co-glycolide (PLGA). An optimized formulation was obtained on the basis of drug entrapment efficiency, gelling behavior and in vitro drug release. The compatibility of the formulation ingredients were tested by Fourier transform infrared (FT-IR) spectroscopy, and differential scanning colorimetry (DSC). SEM study was performed to characterize in v
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Feig, Vivian R., Sanghyun Park, Pier Giuseppe Rivano, et al. "Self-aggregating long-acting injectable microcrystals." Nature Chemical Engineering 2, no. 3 (2025): 209–19. https://doi.org/10.1038/s44286-025-00194-x.

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Abstract Injectable drug depots have transformed our capacity to enhance medication adherence through dose simplification. Central to patient adoption of injectables is the acceptability of needle injections, with needle gauge as a key factor informing patient discomfort. Maximizing drug loading in injectables supports longer drug release while reducing injection volume and discomfort. Here, to address these requirements, we developed self-aggregating long-acting injectable microcrystals (SLIM), an injectable formulation containing drug microcrystals that self-aggregate in the subcutaneous spa
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Kim, Yu Han, Mi Hee Cho, In Bum Song, et al. "Injectable Chitosan Carrier for Demineralized Bone Matrix." Key Engineering Materials 342-343 (July 2007): 177–80. http://dx.doi.org/10.4028/www.scientific.net/kem.342-343.177.

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In this study, we developed an injectable carrier for demineralized bone matrix (DBM) which consists of chitosan and glycerol phosphate (GP). The phase transition behaviors of chitosan and GP solution characterized as a function of temperature. The chitosan and GP solutions were shown to form a sol at room temperature, and the chitosan solution with 10-20 wt% concentrations were found to undergo sol-to-gel phase transitions as the temperature was increased. In situ gel forming implant in vivo was successfully fabricated by simple subcutaneous injection of chitosan and GP solutions with deminer
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Demyanenko, I. A., A. V. Shishkina, Yu S. Hats, and N. V. Kalmykova. "Comparative Study of Injectable Implants Based on Microparticles of Various Biodegradable Materials in a Murine Model of Subcutaneous Implantation." Journal Biomed 18, no. 2 (2022): 63–76. http://dx.doi.org/10.33647/2074-5982-18-2-63-76.

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A comparative study of two commercially available injectable implants based on microparticles of various biodegradable materials (calcium hydroxyapatite and cross-linked collagen) was carried out using a murine model of subcutaneous implantation. The developed experimental model showed that both implants effectively replace the volume of soft tissues. Implant resorption was accompanied by a moderate chronic inflammatory response. The implant based on calcium hydroxyapatite microparticles caused pronounced post-injection swelling at 1 day after administration and demonstrated a more pronounced
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Young, Isabella C., Allison L. Thorson, Roopali Shrivastava, et al. "Dose-Ranging Plasma and Genital Tissue Pharmacokinetics and Biodegradation of Ultra-Long-Acting Cabotegravir In Situ Forming Implant." Pharmaceutics 15, no. 5 (2023): 1487. http://dx.doi.org/10.3390/pharmaceutics15051487.

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HIV continues to affect millions of men and women worldwide. The development of long-acting injectables for HIV prevention can overcome adherence challenges with daily oral prevention regimens by reducing dosing frequency and stigma. We previously developed an ultra-long-acting injectable, biodegradable, and removeable in situ forming implant (ISFI) with cabotegravir (CAB) that demonstrated protection after multiple rectal SHIV challenges in female macaques. Here, we sought to further characterize CAB ISFI pharmacokinetics (PK) in mice by assessing the effect of dose and number of injections o
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Brans, Veerle A., Anna P. Constantinou, Matthew J. Kibble, et al. "Ultrasound-triggered in situ hydrogel formation for spinal disc repair." Journal of the Acoustical Society of America 155, no. 3_Supplement (2024): A324. http://dx.doi.org/10.1121/10.0027676.

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Over 600 million people suffer from lower back pain attributable to spinal disc degeneration. Treatments range from conservative physiotherapy to costly, invasive options like spinal fusion surgery. Injectable engineered materials may allow minimally invasive disc repair, but self-curing lacks process control, and optical in situ curing is depth-limited. We, therefore, propose ultrasound-triggered implant formation, enabling spatiotemporal control at clinically relevant tissue depths. We developed an anionic polysaccharide-based hydrogel, seeded with calcium-loaded thermosensitive liposomes. F
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Cho, Kuk Young, Seongnam Lee, and Jung-Ki Park. "In Situ Micro-Sized Gel-Forming Injectable Implant Using Biodegradable Amphiphilic Graft Copolymer." Macromolecular Bioscience 7, no. 6 (2007): 784–88. http://dx.doi.org/10.1002/mabi.200700045.

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Berdichevski, Alexandra, Haneen Simaan Yameen, Hagit Dafni, Michal Neeman, and Dror Seliktar. "Using bimodal MRI/fluorescence imaging to identify host angiogenic response to implants." Proceedings of the National Academy of Sciences 112, no. 16 (2015): 5147–52. http://dx.doi.org/10.1073/pnas.1502232112.

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Therapies that promote angiogenesis have been successfully applied using various combinations of proangiogenic factors together with a biodegradable delivery vehicle. In this study we used bimodal noninvasive monitoring to show that the host response to a proangiogenic biomaterial can be drastically affected by the mode of implantation and the surface area-to-volume ratio of the implant material. Fluorescence/MRI probes were covalently conjugated to VEGF-bearing biodegradable PEG-fibrinogen hydrogel implants and used to document the in vivo degradation and liberation of bioactive constituents
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Chen, Yan, Yuting Yan, Xiaoming Li, et al. "Osteogenesis Capability and Degradation Property Evaluation of Injectable Biomaterials: Comparison of Computed Tomography and Ultrasound." Journal of Nanomaterials 2013 (2013): 1–8. http://dx.doi.org/10.1155/2013/763937.

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Injectable biomaterials, which can be physically inserted into a target site without the use of surgery, have received increasing attention in tissue engineering during the last decade. There is also a growing need for quantitative evaluation of the injectable biomaterial directly and noninvasively. The objectives of this study are to originate a quantitative noninvasive technique for evaluation of in situ forming bone biomaterials and to validate the feasibility of diagnostic ultrasound images analysis technique. The potential of ultrasound for quantitative evaluation of tissue development wa
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Smiga-Matuszowicz, Monika, Anna Korytkowska-Walach, and Jan Lukaszczyk. "Polymeric in situ forming systems for biomedical applications. Part I. Injectable implants." Polimery 60, no. 03 (2015): 149–59. http://dx.doi.org/10.14314/polimery.2015.149.

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Dissertations / Theses on the topic "In situ injectable implant"

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Jones, Tanya. "Development of a Novel Implant for Drug Delivery." Thesis, Griffith University, 2011. http://hdl.handle.net/10072/367574.

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Background and aim: In situ gelling formulations are liquids that undergo a phase transition to form semi-solid gel structures within the physiological environment. Sustained release of drug products can therefore be delivered via injectable in situ gelling formulations where the gel formed in vivo acts as a drug reservoir, releasing drug via diffusion and/or degradation of the gel. Due to limitations of previously described in situ gelling formulations, the current research project aimed to address these issues and develop a biocompatible injectable in situ gelling formulation/s containing a
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Gomes, Rodrigues Alexandre [Verfasser]. "Parenteral controlled drug delivery by novel direct injectable polymer (DIPO) : in situ forming implant / Alexandre Gomes Rodrigues." Halle, 2018. http://d-nb.info/1160514518/34.

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Fisher, Paul. "Additives to Control Mechanical Properties and Drug Delivery of Injectable Polymeric Scaffolds." UKnowledge, 2014. http://uknowledge.uky.edu/cbme_etds/25.

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In situ forming implants (ISIs) are popular due to their ease of use and local drug delivery potential, but they suffer from high initial drug burst, and release behavior is tied closely to solvent exchange and polymer properties. Additionally, such systems are traditionally viewed purely as drug delivery devices rather than potential scaffold materials due to their poor mechanical properties and minimal porosity. The aim of this research was to develop an injectable ISI with drug release, mechanical, and microstructural properties controlled by micro- and nanoparticle additives. First, an inj
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SHENG, LI. "In Vitro and in Vivo Long-Term Release of Injectable 3-Branch PLA-Retinylamine Conjugate Implant." Case Western Reserve University School of Graduate Studies / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=case1446220233.

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Hess, Jeremy. "In-Situ Testing of Uretek's Injectable Barrier as a Mechanism for Groundwater Control." Scholar Commons, 2016. http://scholarcommons.usf.edu/etd/6095.

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Construction projects involving the installation or repair of subsurface structures or utilities often require dewatering to induce a temporary lowering of the local groundwater elevation to facilitate construction. In the event that a known contaminant plume is present in an adjacent area, this dewatering may inadvertently draw the contaminant into the previously uncontaminated work area. Uretek Holdings, Inc. has developed its Injectable BarrierSM to be installed prior to dewatering exercises to provide a groundwater cut-off by reducing the potential movement of groundwater due to the hydr
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Nizamoglu, Mehmet. "Injectable, in situ crosslinked hydrogels by Fenton’s Reagent (Fe (II) & H2O2) for corneal perforations." Thesis, Uppsala universitet, Institutionen för medicinsk biokemi och mikrobiologi, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-383128.

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Corneal perforations are medical emergencies in which the cornea is partially or completely ruptured, resulting in the loss of stability of the whole eye. Such situations can be caused by bacterial or fungal keratitis, autoimmune, or ocular-surface related disorders. Corneal perforations, if left untreated, can cause partial or total blindness. Therefore, immediate treatment is necessary. The best treatment available is corneal transplantation; however, due to donor limitation, this treatment is non-feasible. Alternatively, applying cyanoacrylate or fibrin glue is the treatment used clinically
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Tran, Anh Hien. "Bacterial biofilm treatment and in situ antimicrobial coatings for orthopaedic implant retention surgery." Thesis, Queensland University of Technology, 2021. https://eprints.qut.edu.au/207850/1/Anh%20Hien_Tran_Thesis.pdf.

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Bacterial biofilms are involved in most device-associated infections. This thesis has developed an in-situ method to treat biofilm and a coculture for testing new antimicrobial biomaterials. We used surface immobilisation to promote Alpha-amylase and silver ion’s disruption of S. aureus biofilms. The treatment also helped coating the surface with silver particles to prevent recurrence. We also formed a coculture of S. aureus and pre-osteoblastic cells and showed that bacteria preferentially attached to the osteoblasts and became more resistant to antibiotic treatment. Overall, this thesis has
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Becerra, Fajardo Laura. "Microcontrolled injectable stimulators based on electronic rectification of high frequency current bursts." Doctoral thesis, Universitat Pompeu Fabra, 2016. http://hdl.handle.net/10803/402433.

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Neuroprostheses based on dense networks of wireless microstimulators have been proposed in the past for restoring movement in paralysis patients. Yet existing implantable microstimulators are too bulky and invasive for implementing such networks because of the powering approaches they employ. To overcome this limitation, it was recently proposed an innovative electrical stimulation method incorporating electronic implants. The method consist in delivering, by means of superficial textile electrodes, high frequency current bursts which innocuously flow through tissues by galvanic coupling and
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Karnaushenko, Dmitriy D. "Compact Helical Antenna for Smart Implant Applications." Doctoral thesis, Universitätsbibliothek Chemnitz, 2017. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-qucosa-230942.

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Medical devices have made a big step forward in the past decades. One of the most noticeable medical events of the twenties century was the development of long-lasting, wireless electronic implants such as identification tags, pacemakers and neuronal stimulators. These devices were only made possible after the development of small scale radio frequency electronics. Small radio electronic circuits provided a way to operate in both transmission and reception mode allowing an implant to communicate with an external world from inside a living organism. Bidirectional communication is a vital featur
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Vialle-Presles, Marie-José. "Etude biochimique et immunohistochimique des collagènes de la peau du rat : application à l'étude de la réhabilitation d'un implant de collagène injectable." Lyon 1, 1985. http://www.theses.fr/1985LYO11681.

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Utilisation de methodes immunohistochimiques pour etudier la repartition dans le derme du rat des macromolecules suivantes: isotypes 1,3,4,5 du collagene, fibronectine et fibres elastiques. Les collagenes des types 1,3 et 5 extraits de la peau du rat ont ete utilises pour la preparation d'anticorps specifiques. Ceux-ci ont permis de localiser ces antigenes dans le derme du rat et de suivre avec precision les phases precoses de la rehabilitation d'un implant de collagene injectable chez le rat
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Books on the topic "In situ injectable implant"

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Copeland, Stephen, and Jai Relwani. Surface replacement of the shoulder. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199550647.003.004008.

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♦ The design of the surface replacement arthroplasty has evolved over the past 20 years. From cemented prostheses such as the SCAN, to cementless prostheses such as the Copeland, the basic concept and design of the surface replacement favouring maximal bone preservation has remained constant.♦ Indications and surgical technique have been refined over this period, the latest modification being the use of computer-assisted navigation to optimise the size and position the implant in situ.♦ Surface replacement prosthesis has demonstrated clinical results at least equal to those of conventional ste
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Book chapters on the topic "In situ injectable implant"

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Rad-Malekshahi, Mazda, and Zahra Kheyri. "Biodegradable In Situ Forming and Preformed Implants." In Biodegradable Long Acting Injectables and Implants. Springer Nature Switzerland, 2025. https://doi.org/10.1007/978-3-031-72302-5_4.

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Deyhle, Hans, Georg Schulz, Bert Müller, et al. "Injectable In Situ-Forming Gel." In Encyclopedia of Nanotechnology. Springer Netherlands, 2012. http://dx.doi.org/10.1007/978-90-481-9751-4_100319.

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Sirivisoot, Sirinrath. "Carbon Nanotube-Based Orthopedic Implant Sensors." In Nanotechnology Enabled In situ Sensors for Monitoring Health. Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-7291-0_7.

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Park, Seung Hun, Yun Bae Ji, Joon Yeong Park, et al. "Injectable In Situ-Forming Hydrogels for Protein and Peptide Delivery." In Advances in Experimental Medicine and Biology. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-3262-7_3.

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Marx, Robert E. "Alveolar Bone Augmentation via In Situ Tissue Engineering." In Horizontal Alveolar Ridge Augmentation in Implant Dentistry: A Surgical Manual. John Wiley & Sons, Inc., 2016. http://dx.doi.org/10.1002/9781119019916.ch31.

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Marx, Robert E. "Alveolar Bone Augmentation via In Situ Tissue Engineering." In Vertical Alveolar Ridge Augmentation in Implant dentistry : A Surgical Manual. John Wiley & Sons, Inc., 2016. http://dx.doi.org/10.1002/9781119082835.ch29.

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Yao, Q., Dong Xiao Li, K. W. Liu, et al. "Primary Study of an Injectable In Situ Composite of Collagen/Calcium Phosphate Porous Scaffold for Bone Substitute." In Bioceramics 18. Trans Tech Publications Ltd., 2006. http://dx.doi.org/10.4028/0-87849-992-x.857.

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Lhotský, Ondřej. "Field Study VII: Field Study of Three Different Injectable Oxygen Sources to Enhance Mono-Aromatic Solvents In Situ Biodegradation." In Advanced Nano-Bio Technologies for Water and Soil Treatment. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-29840-1_19.

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Vaisman, Boris, Ariella Shikanov, Abraham J. Domb, and R. Langer. "Poly(ester-co-anhydride) of Ricinoleic Acid and Sebacic Acid." In Polymer Data Handbook. Oxford University PressNew York, NY, 2009. http://dx.doi.org/10.1093/oso/9780195181012.003.0101.

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Abstract Major Applications Biodegradable polymers for controlled drug delivery in a form of implant or injectable implant (e.g. for the treatment of solid tumors, delivery of local anesthetics, and delivery of antibiotics). Properties of Special Interest Polyester-anhydride of ricinoleic acid (RA) with aliphatic diacids such as sebacic acid (SA) are viscous liquids at low contents of sebacic acid, <40% w/w, (pasty polymers). Pasty polymers that can be mixed with drugs at room temperature and injected into tissue as neat composition are advantageous as they allow simple preparation of d
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Tipton, Arthur, and Richard Dunn. "In Situ Gelling Systems." In Sustained-Release Injectable Products. CRC Press, 2000. http://dx.doi.org/10.1201/b14421-11.

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Conference papers on the topic "In situ injectable implant"

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Bhuckory, Mohajeet B., Nicharee Monkongpitukkul, Andrew Shin, et al. "Enhanced prosthetic vision by upgrading a subretinal photovoltaic implant in-situ." In Ophthalmic Technologies XXXV, edited by Yuankai K. Tao, Daniel X. Hammer, and Derek Nankivil. SPIE, 2025. https://doi.org/10.1117/12.3042241.

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Asadian, Mitra, Fariba Ganji, and Ladan Rashidi. "Sustained release drug delivery system based on MSNs dispersed in an injectable in-situ gelling chitosan hydrogel." In 2024 31st National and 9th International Iranian Conference on Biomedical Engineering (ICBME). IEEE, 2024. https://doi.org/10.1109/icbme64381.2024.10895086.

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Manaspon, C., P. Nittayacharn, K. Vejjasilpa, C. Fongsuk, and N. Nasongkla. "SN-38:β-cyclodextrin inclusion complex for in situ solidifying injectable polymer implants." In 2011 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2011. http://dx.doi.org/10.1109/iembs.2011.6090881.

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Jaafar, Banafsaj, Ahmed Soltan, Jeff Neasham, and Patrick Degenaar. "Optical Recording and stimulation of an Injectable Wireless Medical Implant." In 2018 IEEE British and Irish Conference on Optics and Photonics (BICOP). IEEE, 2018. http://dx.doi.org/10.1109/bicop.2018.8658330.

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"Research on the Preparation of Poloxamer-based Strong Intensity Injectable In-Situ Gel." In 2018 International Conference on Medicine, Biology, Materials and Manufacturing. Francis Academic Press, 2018. http://dx.doi.org/10.25236/icmbmm.2018.39.

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Bishop, Steve, Robert Kaim, Sharad Yedave, Josep Arnó, Frank DiMeo, and Mike Wodjenski. "The Development of In-Situ Ion Implant Cleaning Processes." In ION IMPLANTATION TECHNOLOGY: 16th International Conference on Ion Implantation Technology - IIT 2006. AIP, 2006. http://dx.doi.org/10.1063/1.2401560.

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Ashfaq, Rabia, and Mária Budai-Szűcs. "Factorial design of injectable chlorhexidine in situ gelling system for the treatment of periodontitis." In VI. Symposium of Young Researchers on Pharmaceutical Technology,Biotechnology and Regulatory Science. Institute of Pharmaceutical Technology and Regulatory Affairs, University of Szeged, Faculty of Pharmacy, 2024. http://dx.doi.org/10.14232/syrptbrs.2024.19.

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McKay, C. A., and R. J. Gilbert. "Using cerebrospinal fluid for in situ fabrication of injectable alginate hydrogels for spinal cord repair." In 2011 37th Annual Northeast Bioengineering Conference (NEBEC). IEEE, 2011. http://dx.doi.org/10.1109/nebc.2011.5778586.

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Arno, J. "Report on in-situ antimony fluoride generation for ion implant processes." In Proceedings of the 2002 14th International Conference on Ion Implantation Technology. IEEE, 2002. http://dx.doi.org/10.1109/iit.2002.1258038.

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Martins, Gabriela, Margarida Figueiredo, and Helena Gil. "Development of Injectable and In Situ Solidifying Biomaterials for Vertebral Body Repair—Synthesis, Characterization, and Application." In MATERIAIS. MDPI, 2022. http://dx.doi.org/10.3390/materproc2022008153.

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Reports on the topic "In situ injectable implant"

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Robles, Marcelo, Claudio Dachevsky, and Héctor Llovera. Prospective study: evaluation of the efficacy and longevity of cross-linked hyaluronic acid in nasolabial folds filling. Editorial Lugones, 2023. http://dx.doi.org/10.47196/0574.

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Introduction: the choice of minimally invasive methods positions hyaluronic acid fillers as a leading facial rejuvenation technique. Injectable hyaluronic acid fillers have been widely used in the clinical treatment of facial wrinkles. However, additional information and clinical evidence on the longevity of hyaluronic acid filler after injection is limited. Objectives: to demonstrate the efficacy, safety and longevity of cross-linked HA (AHR) 30 mg/ml (Estrianon Hyaluronic Implant 30® Allanmar International Company S.R.L., Argentina) for filling nasolabial folds (NLF). Design: multicenter, pr
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