Relevant bibliographies by topics / Indolizine

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Indolizine'

Author: Grafiati
Published: 4 June 2021
Last updated: 25 July 2025

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Journal articles on the topic "Indolizine"

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Albota, Florin, Mino R. Caira, Constantin Draghici, Florea Dumitrascu, and Denisa E. Dumitrescu. "Sydnone C-4 heteroarylation with an indolizine ring via Chichibabin indolizine synthesis." Beilstein Journal of Organic Chemistry 12 (November 23, 2016): 2503–10. http://dx.doi.org/10.3762/bjoc.12.245.

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The synthesis of sydnones heteroarylated at C-4 with an indolizine was achieved by Chichibabin (Tschitschibabin) indolizine synthesis starting from the corresponding sydnone-N-pyridinium bromides. The latter compounds were also transformed to sydnone-indolizines connected through a keto group at the C-4 position by refluxing them in 1,2-epoxybutane with an activated alkyne. The structures of the new compounds were assigned by FTIR, NMR spectroscopy and X-ray analysis.
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Guidotti, Bruno Boni, Thiago Sabino da Silva, José Tiago Menezes Correia, and Fernando Coelho. "Brønsted-acid-catalyzed selective Friedel–Crafts monoalkylation of isatins with indolizines in water." Organic & Biomolecular Chemistry 18, no. 37 (2020): 7330–35. http://dx.doi.org/10.1039/d0ob01714k.

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Chan, Siu-Chung, Chi-Fung Yeung, Hau-Lam Shek, et al. "Iron(ii)-induced cycloisomerization of alkynes via “non-vinylidene” pathways for iron(ii)-indolizine and -indolizinone complexes." Chemical Communications 56, no. 83 (2020): 12644–47. http://dx.doi.org/10.1039/d0cc05081d.

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Botezatu (Dediu), Andreea Veronica, Georgiana Horincar, Ioana Otilia Ghinea, et al. "Whole-Cells of Yarrowia lipolytica Applied in “One Pot” Indolizine Biosynthesis." Catalysts 10, no. 6 (2020): 629. http://dx.doi.org/10.3390/catal10060629.

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A series of yeast strains was tested in order to evaluate their catalytic potential in biocatalysis of one-pot indolizine’s synthesis. Yeast cultivation was performed in a submerged system at 28 °C for 72 h at 180 rpm. An assessment of the reagents’ toxicity on yeast viability and metabolic functionality concluded that the growth potential of three Yarrowia lipolytica strains were least affected by the reactants compared to the other yeast strains. Further, crude fermentation products (biomass and cell-free supernatant)—obtained by submerged cultivation of these yeasts—were used in multistep c
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Venugopala, Katharigatta N., Sandeep Chandrashekharappa, Subhrajyoti Bhandary, et al. "Efficient Synthesis and Characterization of Novel Substituted 3-Benzoylindolizine Analogues via the Cyclization of Aromatic Cycloimmoniumylides with Electrondeficient Alkenes." Current Organic Synthesis 15, no. 3 (2018): 388–95. http://dx.doi.org/10.2174/1570179414666171024155051.

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Background: Indolizine pharmacophore is known to exhibit various promising pharmacological properties such as analgesic, anticancer, antihistaminic, antidiabetic, anti-inflammatory, antileishmanic, antimicrobial, antimutagenic, antioxidant, antitubercular, antiviral, larvicidal and herbicidal activities. Objective: In the present investigation, it was envisaged to synthesize a series of novel ethyl-7-substituted-3-(4- substituted benzoyl)-2-substituted indolizine-1-carboxylates by employing chromium(IV)oxide as dehydrogenating agent with triethylamine combination. Method: Synthesis of a series
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Ma, Lanchao, Bing Chen, Yunlong Guo, et al. "NIR polymers and phototransistors." Journal of Materials Chemistry C 6, no. 47 (2018): 13049–58. http://dx.doi.org/10.1039/c8tc03917h.

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A novel bisthiophene-fused diketopyrrolopyrrole unit (4,11-bis(2-octyldodecyl)-7H,14H-thieno[3′,2′:7,8]indolizino[2,1-a]thieno[3,2-g]indolizine-7,14-dione, BTI) has been designed as an electron acceptor and used to copolymerize with thiophene and bithiophene as electron donors to construct two D–A conjugated polymers, P1 and P2via Stille coupling, respectively.
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Chudík, Miloslav, Štefan Marchalín, and Katarína Havrilová. "Synthesis and Spectral Properties of Methyl 6-Acetyl- or 6-Cyano-3-amino-2-benzoyl-7-furyl-5-methylindolizine-8-carboxylates." Collection of Czechoslovak Chemical Communications 63, no. 6 (1998): 826–34. http://dx.doi.org/10.1135/cccc19980826.

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Good yields of methyl 6-acetyl- or 6-cyano-3-amino-2-benzoyl-5-methyl-7-(5-substituted-2-furyl)indolizine-8-carboxylates (5a-5f) were obtained in the reaction of corresponding 5-acetyl- or 5-cyano-2-formyl-4-(5-substituted-2-furyl)-6-methyl-1,4-dihydropyridine-3-carboxylated (4a-4f) with 3-phenyl-3-oxopropanenitrile. Spectral properties of the indolizines 5 are discussed.
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Mizuno, Shohta, Takashi Nishiyama, Hana Bessho, et al. "Total Synthesis and Biological Evaluation of 22-Hydroxyacuminatine and the Related Natural Products Norketoyobyrine and Naucleficine." Molecules 30, no. 12 (2025): 2650. https://doi.org/10.3390/molecules30122650.

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Aromathecin compounds—which contain the same indolizine core structure as camptothecin-like compounds—are expected to show anticancer activity. Among them, 22-hydroxyacuminatine—which has a substituent on the E-ring of the pentacyclic scaffold—exhibits topoisomerase 1 inhibitory activity; therefore, the development of efficient methods for its synthesis has been actively pursued. Herein, we report a versatile synthetic methodology for introducing various substituents on the E-ring, leading to the total synthesis of 22-hydroxyacuminatine as a model compound of the aromathecin family. The synthe
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Venugopala, Katharigatta N., Christophe Tratrat, Melendhran Pillay, et al. "Anti-Tubercular Activity of Substituted 7-Methyl and 7-Formylindolizines and In Silico Study for Prospective Molecular Target Identification." Antibiotics 8, no. 4 (2019): 247. http://dx.doi.org/10.3390/antibiotics8040247.

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Novel series of diversely substituted indolizines were designed, synthesized, and evaluated for their in vitro anti-mycobacterial activity against H37Rv and multi-drug-resistant (MDR) strains of Mycobacterium tuberculosis (MTB). Many compounds exhibited significant inhibitory activity against MTB H37Rv strains. Indolizines 2d, 2e, and 4 were also found to be active against MTB clinical isolates with multi-resistance to rifampicin and isoniazid. Indolizine 4 was identified as the most promising anti-mycobacterial agent, displaying minimum inhibitory concentration (MIC) values of 4 and 32 μg/mL
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Matsumoto, Kiyoshi, Yukio Ikemi, Motoo Shiro, Takane Uchida, and James William Lown. "Reactions of 5-cyano-1,4-diphenylpyridazino[4,5-a]indolizines with dimethyl acetylenedicarboxylate: regioselective formation of 1:2 Michael type adducts." Canadian Journal of Chemistry 71, no. 4 (1993): 529–33. http://dx.doi.org/10.1139/v93-075.

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Reactions of 5-cyano-1,4-diphenylpyridazino[4,5-a]indolizines with dimethyl acetylenedicarboxylate afforded the 1:2 adducts regioselectively and, unexpectedly, in a Michael fashion rather than in a 1,3-dipolar manner. The structure of the products was established by X-ray crystallography. Regiospecific formation of the observed product 3 can be explained by the higher nucleophilicity of the nitrogen at the 2 position than at the 3 position of the 5-cyano-1,4-diphenylpyridazino[4,5-a]indolizine 1 owing to the contribution of a resonance structure 5 to the hybrid. This favors two successive Mich
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Dissertations / Theses on the topic "Indolizine"

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Bode, Moira Leanne. "Synthetic and spectroscopic studies of indolizine derivatives." Thesis, Rhodes University, 1994. http://hdl.handle.net/10962/d1005050.

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The crystalline compound resulting from thermal cyclization of the Baylis-Hillman product, methyl 3-hydroxy-2-methylene-3-(2-pyridyl)propanoate, has been identified as the indolizine derivative, methyl indolizine-2-carboxylate, and this approach involving the reaction of pyridine-2-carboxaldehydes and acrylate analogues has been established as a general route to 2-substituted indolizines. The ease of cyclization the Baylis-Hillman products to indolizines has been shown to increase by converting the hydroxy group to an acetoxy group, and a range of acetylated Baylis-Hillman products were prepar
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Sevrain, Nicolas. "Synthèse de nouveaux systèmes phosphorés à chiralité axiale et leurs applications." Thesis, Montpellier, Ecole nationale supérieure de chimie, 2017. http://www.theses.fr/2017ENCM0019.

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La demande croissante de molécules énantiopures pour la chimie pharmaceutique et agrochimique est l'un des enjeux majeurs actuels de l'industrie chimique. De plus, les nouvelles réglementations environnementales récentes forcent l'émergence de procédés efficaces, rentables et respectueux de l'environnement pour la fabrication de ces nouvelles entités chimiques. Les méthodes impliquant l'utilisation de catalyseurs présentent des avantages évidents par rapport à des méthodes stœchiométriques. À ce titre, les ligands phosphorés ont joué un rôle clé dans l'évolution de la catalyse asymétrique. Leu
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Stegarescu-Furdui, Bianca. "Synthèse en série bipyridine. Etude de l'interaction avec l'ADN." Phd thesis, Université Joseph Fourier (Grenoble), 2006. http://tel.archives-ouvertes.fr/tel-00166634.

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Nous avons développé la synthèse d'hétérocycles indoliziniques fonctionnalisés par un cation pyridinium et étudié leur interaction avec L'ADN. L'étape-clé pour accéder aux indolizines est la cycloaddition [3+2]-dipolaire des ylures dérivés des sels quaternaires de la 4,4'-bipyridine avec des dipolarophiles. La synthèse a été effectuée par la voie classique (chauffage en solvant) et par irradiation avec des micro-ondes (“chimie verte”). Nous avons étudié les propriétés acido-basiques des sels diquaternaires et leur activité biologique sur une série de microorganismes. Par ailleurs les propriété
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Martinez, Thibaut. "Cyclisation de 2-pyridylallènes : vers de nouveaux dérivés d’indolizines et ligands carbéniques chiraux." Thesis, Sorbonne université, 2019. https://accesdistant.sorbonne-universite.fr/login?url=http://theses-intra.upmc.fr/modules/resources/download/theses/2019SORUS273.pdf.

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Les travaux réalisés dans le cadre de cette thèse sont consacrés à l’étude de réactions de cyclisations de 2-pyridylallènes à l’aide de différentes espèces électrophiles. Des 2-pyridylallènes tétrasubstitués ont ainsi été synthétisés et cyclisés en conditions acides, avec différents halogènes électrophiles, des chalcogènes ainsi que de l’or (I) pour donner de nouveaux motifs indoliziniums. Des indolizines 1,3-substitués iodées en position 2 ont également été obtenues permettant une post-fonctionnalisation par couplage croisé. L’utilisation d’or (I) comme électrophile mène à de nouveaux complex
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Stegarescu-Furdui, Bianca. "Synthèse en série bipyridine. Etude de l'interaction avec l'ADN." Phd thesis, Grenoble 1, 2006. http://www.theses.fr/2006GRE10187.

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Nous avons développé la synthèse d’hétérocycles indoliziniques fonctionnalisés par un cation pyridinium et étudié leur interaction avec L’ADN. L’étape-clé pour accéder aux indolizines est la cycloaddition [3+2]-dipolaire des ylures dérivés des sels quaternaires de la 4,4’-bipyridine avec des dipolarophiles. La synthèse a été effectuée par la voie classique (chauffage en solvant) et par irradiation avec des micro-ondes (“chimie verte”). Nous avons étudié les propriétés acido-basiques des sels diquaternaires et leur activité biologique sur une série de microorganismes. Par ailleurs les propriété
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Beck, Daniel Antony Speedie, and beckautomatic@gmail com. "Stereoselective intramolecular Michael addition reactions of pyrrole and their application to natural product syntheses." The Australian National University. Research School of Chemistry, 2006. http://thesis.anu.edu.au./public/adt-ANU20070130.130009.

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Chapter one; “(-)-Rhazinilam and (-)-Rhazinal: Alkaloids with Anti-mitotic Properties Derived from Kopsia teoi”, provides the background information behind the motives that initiated this research project. The plant alkaloid (-)-rhazinilam [(-)-1] and its naturally-occurring derivative (-)-rhazinal [(-)-13] both exhibit potent anti-mitotic activities and, as such, are interesting targets for total synthesis. Chapter one is a review of the literature regarding these two compounds and discusses the occurrence, proposed biosynthetic origins, structural elucidation and biological activites of c
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Gizolme, Marie. "Réactions multicomposants et isonitriles." Phd thesis, Ecole Polytechnique X, 2007. http://pastel.archives-ouvertes.fr/pastel-00003258.

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Les couplages de Passerini et de Ugi, réactions multicomposants impliquant des isonitriles, ont suscité un grand intérêt ces dernières années. En effet elles permettent d'obtenir en une étape, avec de bons rendements globaux, des produits complexes et diversifiés. Tout d'abord, une nouvelle méthode de synthèse d'indolizines a été développée à partir d'un couplage entre réaction d'Ugi et cycloaddition [3+2] de sel de pyridinium. Cette étape-clé s'insère dans une cascade Sonogashira/cycloaddition/oxydation qui permet d'accéder de manière rapide à des systèmes hétérocycliques d'une grande complex
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Tukulula, Matshawandile. "The design and synthesis of novel HIV-1 protease inhibitors." Thesis, Rhodes University, 2009. http://eprints.ru.ac.za/1563/.

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Delattre, François. "Nouveaux senseurs fluorescents à base de β-cyclodextrine incorporant l'unité pyridinoindolizinique : synthèse, détermination structurale et étude de l'inclusion". Littoral, 2003. http://www.theses.fr/2003DUNK0097.

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Ce travail concerne la synthèse et la caractérisation d'une série de nouveaux senseurs fluorescents, à base de β-cyclodextrine, incorporant l'unité pyridinoindolizinique. Ces dispositifs macromoléculaires ont pour caractéristiques d'induire une variation d'intensité de leurs émissions de fluorescence lors de l'inclusion de molécules invitées, à l'intérieur de leur partie macrocyclique. Dans une première partie, nous avons mis au point deux voies de synthèse dont le principe général repose sur des réactions de cycloadditions-1,3 dipolaires, à partir de sels quaternaires de 4,4'-bipyridinium et
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Granger, Devin B. "ACENES, HETEROACENES AND ANALOGOUS MOLECULES FOR ORGANIC PHOTOVOLTAIC AND FIELD EFFECT TRANSISTOR APPLICATIONS." UKnowledge, 2017. http://uknowledge.uky.edu/chemistry_etds/76.

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Polycyclic aromatic hydrocarbons composed of benzenoid rings fused in a linear fashion comprise the class of compounds known as acenes. The structures containing three to six ring fusions are brightly colored and possess band gaps and charge transport efficiencies sufficient for semiconductor applications. These molecules have been investigated throughout the past several decades to assess their optoelectronic properties. The absorption, emission and charge transport properties of this series of molecules has been studied extensively to elucidate structure-property relationships. A wide variet
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Books on the topic "Indolizine"

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Lee, Youngjun. Systematic Exploration of Indolizine-Based Small Fluorescent Molecules. Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-13-1645-6.

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Kallatsa, Oili. Polyhydroxylated indolizidine alkaloids: The synthesis of castanospermine analogues. Oulun yliopisto, 1999.

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Jaecques, Ryan Patrick. Studies toward the synthesis of indolizidine alkaloids and analogues using ring-closing metathesis. National Library of Canada, 2003.

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Lee, Youngjun. Systematic Exploration of Indolizine-Based Small Fluorescent Molecules: Synthesis, Analysis and Application. Springer, 2018.

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Lee, Youngjun. Systematic Exploration of Indolizine-Based Small Fluorescent Molecules: Synthesis, Analysis and Application. Springer, 2018.

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Maier, Wolfram. Cyclisierungsreaktionen von konjugierten, heteroaromatischen Dipolsystemen: Ein neuer Zugang zu Derivaten des Indolizins, Chinolizins und Pyrido[1,2-a]azepins. 1993.

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Book chapters on the topic "Indolizine"

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Lee, Youngjun. "Introduction." In Systematic Exploration of Indolizine-Based Small Fluorescent Molecules. Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-13-1645-6_1.

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Lee, Youngjun. "A Comprehensive Studies of an Indolizine-Based Seoul-Fluor System." In Systematic Exploration of Indolizine-Based Small Fluorescent Molecules. Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-13-1645-6_2.

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Lee, Youngjun. "Tetrazine-Containing Colorful Bioorthogonal Probes Based on the Indolizine Core Skeleton." In Systematic Exploration of Indolizine-Based Small Fluorescent Molecules. Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-13-1645-6_3.

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Lee, Youngjun. "Rational Development of Furoindolizine Core Skeleton Guided by Oscillator Strength." In Systematic Exploration of Indolizine-Based Small Fluorescent Molecules. Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-13-1645-6_4.

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Blewitt, H. L. "Indolizine and Aza Derivatives With Additional Nitrogens in the 5-Membered Ring." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470187005.ch2.

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Brandi, Alberto, Francesca Cardona, Stefano Cicchi, Franca M. Cordero, and Andrea Goti. "Enantiopure Pyrroline-N-Oxides for the Synthesis of Pyrrolizine and Indolizine Alkaloids." In Current Trends in Organic Synthesis. Springer US, 1999. http://dx.doi.org/10.1007/978-1-4615-4801-0_27.

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Shelke, R. N., A. B. Kanagare, S. U. Deshmukh, et al. "An Overview of the Synthesis of Pyrroline, Indolizine, and Quinolizinium Derivatives Using Different Nanocatalysts." In Nanocatalysis. CRC Press, 2022. http://dx.doi.org/10.1201/9781003141488-3.

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Babaev, Eugene V. "Fluorinated Indolizines." In Fluorine in Heterocyclic Chemistry Volume 1. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-04346-3_4.

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Seigler, David S. "Pyrrolizidine, Quinolizidine, and Indolizidine Alkaloids." In Plant Secondary Metabolism. Springer US, 1998. http://dx.doi.org/10.1007/978-1-4615-4913-0_30.

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Dorling, P. R., S. M. Colegate, and C. R. Huxtable. "Swainsonine: A Toxic Indolizidine Alkaloid." In Toxicants of Plant Origin. CRC Press, 2024. http://dx.doi.org/10.1201/9781003575030-9.

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Conference papers on the topic "Indolizine"

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Yang, Zhen, Yefei Wang, Fengtao Zhan, et al. "Investigation of High-efficient Acidizing Inhibitors: Structure and Anti-corrosion Performance of Novel Indolizine Derivatives." In CORROSION 2019. NACE International, 2019. https://doi.org/10.5006/c2019-12744.

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Abstract The novel indolizine derivative inhibitor for acidizing shows an effective corrosion inhibition without the synergism of propargyl alcohol. The inhibitive indolizine derivatives were generated from BQC (Benzyl Quinolinium Chloride, a commonly used key compound in acidizing inhibitor) via a moderate 1,3-dipolar cycloaddition mechanism. High Resolution Mass Spectrometry (HRMS) and NMR were used to confirm the detailed chemical structure. The inhibition of two indolizine derivatives in 15 wt.% HCl for N80 steel were studied by weight loss measurement and electrochemical analysis. Without
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Ciorteanu, Roxana Elena, Monica Sardaru, Dumitrela Diaconu, Ionel Mangalagiu, and Ramona Danac. "Synthesis and anticancer properties of new indolizinic derivatives." In Scientific seminar with international participation "New frontiers in natural product chemistry". Institute of Chemistry, Republic of Moldova, 2023. http://dx.doi.org/10.19261/nfnpc.2023.ab25.

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Natural compounds with indolizine scaffolds have demonstrated numerous biological activities and have found use in medical research laboratories. Thys, the unique indolizine scaffold became an important system for the development of new drug candidates in medicinal chemistry. [1,2] Several indolizines with excellent anticancer activity and tubulin polymerization inhibitory potency have been reported recently, and our group contributed also to the field. [1,3] The goal of this study was the design, synthesis and anticancer evaluation of several new derivatives with symmetrical or unsymmetrical
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Yang, Zhen, Yefei Wang, Matjaž Finšgar, Jiajia Wu, and Wengang Ding. "Novel High-Efficient Key Component of Steel Corrosion Inhibitors Formulation for Acidification: Indolizine Derivatives of the Conventional N-Heterocyclic Quaternary Ammonium Salts." In SPE International Conference on Oilfield Chemistry. SPE, 2023. http://dx.doi.org/10.2118/213814-ms.

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Abstract Acidizing, the widely used technique for well stimulation, requires a great consumption of effective Corrosion Inhibitors (CIs), due to the severe and fast corrosion of metallic equipment caused by strong hot acid as soon as the acidizing fluids are pumping down to reservoir. This paper presents a new concept of indolizine derivative inhibitors with remarkable inhibition effectiveness for steel under acidizing condition, which will reduce the cost and environmental burden of acidizing CIs significantly. Indolizine derivatives of several quinolinium salts (serves as main component of c
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Yang, Zhen, Yefei Wang, Matjaž Finšgar, et al. "Novel High-Effective Component for Acidizing Corrosion Inhibitors: Indolizine Derivatives of the Quaternary Quinolinium Salts." In SPE Asia Pacific Oil & Gas Conference and Exhibition. Society of Petroleum Engineers, 2020. http://dx.doi.org/10.2118/202369-ms.

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Yang, Zhen, Yefei Wang, Renzhuo Wang, et al. "Insight of New Eco-Friendly Acidizing Corrosion Inhibitor: Structure and Inhibition of the Indolizine Derivatives." In SPE International Conference on Oilfield Chemistry. Society of Petroleum Engineers, 2019. http://dx.doi.org/10.2118/193555-ms.

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Wang, Renzhuo, Zhen Yang, Wuhua Chen, Yefei Wang, Mingchen Ding, and Fengtao Zhan. "Structure and Inhibition of the Indolizine Derivative: New Concept of High-Efficient Corrosion Inhibitors for Acidizing." In International Petroleum Technology Conference. International Petroleum Technology Conference, 2019. http://dx.doi.org/10.2523/19413-ms.

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Wang, Renzhuo, Zhen Yang, Wuhua Chen, Yefei Wang, Mingchen Ding, and Fengtao Zhan. "Structure and Inhibition of the Indolizine Derivative: New Concept of High-Efficient Corrosion Inhibitors for Acidizing." In International Petroleum Technology Conference. International Petroleum Technology Conference, 2019. http://dx.doi.org/10.2523/iptc-19413-ms.

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Wang, Yefei, Zhen Yang, Renzhuo Wang, et al. "High-efficiency Corrosion Inhibitor for Acidizing: Synthesis, Characterization and Anti-corrosion Performance of Novel Indolizine Derivative." In SPE International Conference on Oilfield Chemistry. Society of Petroleum Engineers, 2019. http://dx.doi.org/10.2118/193587-ms.

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Shalin, N. I., O. D. Fominykh, A. A. Kalinin, and M. Yu Balakina. "Molecular modeling in design of nonlinear-optical polymer materials doped with indolizine chromophores with isolating groups in donor and acceptor moieties." In ACTUAL PROBLEMS OF ORGANIC CHEMISTRY AND BIOTECHNOLOGY (OCBT2020): Proceedings of the International Scientific Conference. AIP Publishing, 2022. http://dx.doi.org/10.1063/5.0069653.

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Amaral, Mônica F. Z. J., Amanda A. Baumgartner, and Giuliano C. Clososki. "Base/Electrophile-Controlled Regioselective Functionalization of 1-Substituted-Indolizines." In 15th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_2013912181622.

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You might also be interested in the extended bibliographies on the topic 'Indolizine' for particular source types:
Journal articles Dissertations / Theses
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