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1

Slyvka, N. O. "Systemic inflammatory response as a part of hepatorenal syndrome." Thesis, БДМУ, 2020. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/18059.

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Chen, Xu-wu. "Neutrophil-endothelium interactions in patients with systemic inflammatory response syndrome." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ29673.pdf.

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3

Chen, Xu-wu 1955. "Neutrophil-endothelium interactions in patients with systemic inflammatory response syndrome." Thesis, McGill University, 1996. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=27298.

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Multiple Organ Dysfunction Syndrome (MODS) is associated with high mortality in patients admitted to the surgical intensive care unit (SICU). MODS begins with a systemic response described as Systemic Inflammatory Response Syndrome (SIRS). Studies on SIRS patients may provide an insight into the mechanisms by which SIRS progresses to MODS. In this thesis, the interactions between circulating polymorphonuclear neutrophils (PMNs) from patients with SIRS and endothelial cells (ECs) from human umbilical veins were measured in order to elucidate the mechanism for PMN adhesion and subsequent cytotox
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Sydorchuk, Ryslan Ihorovuch, Oleg Yosypovych Khomko, Ruslan Ihorovych Polyanskyi, and Oleksandr Matviyovych Plegutsa. "Systemic inflammatory response syndrome associated with pancreatitis: efficacy of passive immunotherapy." Thesis, Вінницький національний медичний університет ім. М.І.Пирогова, 2015. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/10764.

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5

Price, Susanna. "Role of vasoactive mediators in the modulation of cardiac function in sepsis." Thesis, Imperial College London, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.271284.

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6

Pevec, Till. "Dexamethason-21-isonicotinat als Begleittherapie bei Kühen mit Systemic Inflammatory Response Syndrome." Doctoral thesis, Universitätsbibliothek Leipzig, 2007. http://nbn-resolving.de/urn:nbn:de:bsz:15-20071210-143013-1.

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Dexamethason-21-isonicotinat als Begleittherapie bei Kühen mit Systemic Inflammatory Response Syndrome Schlüsselwörter: Dexamethason, SIRS, Phagozytoseaktivität/Burstaktivität von Monozyten und neutrophilen Granulozyten, Tumornekrose Faktor alpha
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7

Keyser, Eric J. "Exhaled nitric oxide and the Systemic Inflammatory Response Syndrome (SIRS) after cardiac surgery." Thesis, McGill University, 2001. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=31247.

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Background. Septic patients produce increased nitric oxide (NO). We postulated increased exhaled nitric oxide (exNO) in SIRS after cardiopulmonary bypass surgery (CPB).<br>Methods. Forty-two intubated patients were studied postoperatively and at two-hour intervals for eight hours or until extubated. Hemodynamic indices, including indexed systemic vascular resistance (SVRi) and cardiac index (CI) were measured. ExNO was analyzed by ozone chemiluminescence.<br>Results. Six patients (14%) Manifested SIRS, defined as SVRI <1800 dynes&middot;sec/cm5/m2. ExNO indexed by expired volume of minute vent
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8

Lewis, A. "Modulation of the systemic inflammatory response syndrome in lower limb ischaemia-reperfusion injury." Thesis, Queen's University Belfast, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.421004.

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9

Harkin, Denis William. "Modulation of the systemic inflammatory response syndrome in lower limb ischaemia-reperfusion injury." Thesis, Queen's University Belfast, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326388.

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10

Hoffman, Crystal Joyce. "Glucocorticoid Receptor Density and Binding Affinity in Horses with Systemic Inflammatory Response Syndrome." Thesis, Virginia Tech, 2014. http://hdl.handle.net/10919/48423.

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There were three objectives of this study. The first was to determine if commercially available fluorochromes could be used to determine the glucocorticoid receptor (GR) density and binding affinity (BA) in equine peripheral blood mononuclear cells. The second was to determine if there was a correlation between elevated plasma cortisol and GR density or binding affinity in healthy adult horses. The third objective was to evaluate the HPA axis in adult horses presenting with systemic inflammatory response syndrome (SIRS), and to determine where any alterations in HPA axis function occur in t
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11

Sutherland, Ainsley M. "Genetic determinants of the host response to infection in critically ill adults with systemic inflammatory response syndrome." Thesis, University of British Columbia, 2007. http://hdl.handle.net/2429/31527.

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Background. Activation of a systemic inflammatory response to infection varies significantly between individuals with important clinical implications. Genotype contributes substantially to outcome of infectious disease. Hypothesis. Allelic variants of inflammatory and innate immunity genes affect protein levels and function and are predictive of outcome in critically ill adults who have systemic inflammatory response syndrome (SIRS). Methods. Clinical data for derivation and validation cohorts of critically ill Caucasian patients with SIRS were collected for 28 days after admission to ICU and
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Pilypienė, Ingrida. "Significance of Foetal Inflammatory Response Syndrome on Health and Psychomotor Development in Premature Infants." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2012. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120601_102857-39598.

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Improved perinatal care during the last few years has led to higher survival rates for preterm infants. However, with higher survival rates, the number of children demonstrating long-term health disorders that result in a poorer quality of life is increasing. The most common complications in those preterm children include motion disorders, vision and hearing impairment, mental disorders, and chronic lung disease. Intrauterine infection may cause foetal infection and inflammation thus inducing the inflammatory response in foetus, defined by foetal inflammatory response syndrome (FIRS). FIRS may
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13

Davarya, Shekar Ligia. "Inflammatory and Thrombotic Responses to Microbial Products in Fetal Vessels Are Mediated through Divergent Toll-Like Receptor Signaling Pathways: Implications in Fetal Inflammatory Response Syndrome." Yale University, 2008. http://ymtdl.med.yale.edu/theses/available/etd-08072007-132134/.

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Placental vessels and the umbilical circulatory network function to carry oxygen and nutrients to the fetus. It is at this level that placental lesions such as villitis, obliterative vasculopathy, and thrombotic vasculopathy have been observed in association with fetal inflammatory response syndrome (FIRS) and cerebral palsy. We used human umbilical vein endothelial cells (HUVECs) as a model to study the regulation of inflammation and thrombosis in fetal vessels by microbial products. In this thesis we measured interleukin-8 (IL-8) and tissue factor (TF) expression by HUVECs treated with lipop
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Davarya, Shekar Ligia. "Inflammatory and thrombotic responses to microbial products in fetal vessels are mediated through divergent toll-like receptor signaling pathways implications in fetal inflammatory response syndrome /." [New Haven, Conn. : s.n.], 2007. http://ymtdl.med.yale.edu/theses/available/etd-08072007-132134/.

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15

Boyes, Simon Ashley. "The role of preoperative antioxidant status in the development of the systematic inflammatory response syndrome in elective aortic aneurysm repair." Thesis, University of Southampton, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.430709.

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16

Lahiri, Rajiv. "Changes in innate immune function predict post-operative systemic inflammatory response syndrome (SIRS) following major hepatico-pancreatico-biliary (HPB) surgery." Thesis, Queen Mary, University of London, 2014. http://qmro.qmul.ac.uk/xmlui/handle/123456789/8952.

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Introduction Patients undergoing major surgery are at risk of life-threatening complications including systemic inflammatory response syndrome (SIRS) and sepsis. Early identification of patients at risk of SIRS would allow tailored post-operative care and improve survival. Elevated serum IL-6 levels have been shown patients with poor post-operative outcomes, but the mechanisms underlying this response are unknown. We studied these mechanisms in patients undergoing major surgery to identify early biomarkers of altered inflammatory responses and poor clinical outcomes. Methods Serial blood sampl
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Engel, Julia [Verfasser]. "Mittels Multiplate® Analyzer bestimmte Thrombozytenfunktion bei Kleinpferden und Ponys sowie bei Equiden mit Systemic Inflammatory Response Syndrome / Julia Engel." Gieߟen : Universitätsbibliothek, 2020. http://d-nb.info/1216143684/34.

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18

Schaefer, Helen Leanne [Verfasser]. "Investigations on the quantitative and qualitative protein excretion in urine of dogs with Severe Inflammatory Response Syndrome (SIRS) / Helen Leanne Schaefer." Berlin : Freie Universität Berlin, 2012. http://d-nb.info/1027151302/34.

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19

Gebhardt, Constance. "Systemic-inflammatory-response-Syndrome und Sepsis beim Hund : Untersuchung von klinischen, hämatologischen, blutchemischen und gerinnungsdiagnostischen Parametern sowie des C-reaktiven Proteins /." Berlin : Mbv, Mensch-und-Buch-Verl, 2009. http://d-nb.info/998071498/04.

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20

Cavalcante, Ana Augusta Monteiro. "Enteral nutrition supplemented with l-glutamine and its action on the inflammatory process, the glycolytic metabolism, the immune system and the oxidative stress of patients with systemic inflammatory response syndrome." Universidade Federal do CearÃ, 2010. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=5260.

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Conselho Nacional de Desenvolvimento CientÃfico e TecnolÃgico<br>The Systemic Inflammatory Response Syndrome (SIRS) is characterized by an excessive release of inflammatory mediators as a systemic inflammatory response to a serious clinical injuries. The use of glutamine in nutraceutical doses has been studied as a strategy in tissue protection and preservative of tissue metabolic function in stressful situations, helping to improve the immune response of patients. The effects of enteral glutamine supplementation in nutraceutical doses on the inflammatory markers, of glycolytic metabolism, of
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21

Machaca, Quea Nancy Roxana, Ventura Sonia Salazar, and Teves Pedro Montes. "Síndrome de respuesta inflamatoria sistémica como indicador pronóstico en pacientes cirróticos hospitalizados." Sociedad de Gastroenterología del Perú, 2014. http://hdl.handle.net/10757/331955.

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narmq2@hotmail.com<br>Objetivo: La inflamación sistémica empeora los trastornos circulatorios en el paciente cirrótico y recientemente el síndrome de respuesta inflamatoria sistémica (SRIS) podría ser un indicador pronóstico en ellos. El objetivo del estudio fue determinar si la presencia de SRIS al ingreso en pacientes cirróticos hospitalizados está asociada a complicaciones o mortalidad. Materiales y métodos: Estudio de cohortes retrospectiva, realizado en el Hospital Nacional Daniel Alcides Carrión. Se admitieron pacientes cirróticos hospitalizados desde julio 2008 hasta diciembre 2
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22

Ortlieb, Lutz Volker [Verfasser]. "Bedeutung eines Fast-Track-Konzeptes für die systemische Inflammation (systemic inflammatory response syndrome = SIRS) nach offener Aneurysmaausschaltung [[Elektronische Ressource]] / Lutz Volker Ortlieb." Ulm : Universität Ulm. Medizinische Fakultät, 2013. http://d-nb.info/1036215199/34.

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23

Gebhardt, Constance [Verfasser]. "Systemic Inflammatory Response Syndrome und Sepsis beim Hund : Untersuchung von klinischen, hämatologischen, blutchemischen und gerinnungsdiagnostischen Parametern sowie des C-reaktiven Proteins / Constance Gebhardt." Berlin : Freie Universität Berlin, 2009. http://d-nb.info/1023751461/34.

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24

Pilypienė, Ingrida. "Vaisiaus uždegiminio atsako sindromo įtaka neišnešioto naujagimio sveikatai ir psichomotorinei raidai." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2012. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120601_102908-05709.

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Dėl pagerėjusios perinatalinės priežiūros per pastaruosius metus neišnešiotų naujagimių išgyvenamumas labai pagerėjo. Tačiau, kai neišnešiotų naujagimių išgyvena vis daugiau, daugėja ir vaikų, kuriems augant, išryškėja ilgalaikiai sveikatos sutrikimai, pabloginantys jų gyvenimo kokybę. Nurodoma, kad dažniausia neišnešioto naujagimio gimimo priežastis yra intrauterinė infekcija, kuri progresuodama gali inicijuoti vaisiaus uždegiminio atsako sindromą, kurio metu vaisiuje suintensyvėja uždegiminių citokinų IL-1, IL-6, IL-8, TNF-α, augimo veiksnių gamyba. Šio sindromo pasekmė - sunkūs vaisiaus ir
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25

Corrêa, Sílvia Verônica de Magalhães e. "Avaliação da tromboelastografia em cães clinicamente normais e na detecção precoce da coagulação intravascular disseminada (CID) em cães com pancreatite." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/10/10136/tde-08052017-100403/.

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A Coagulação Intravascular Disseminada (CID) é uma síndrome caracterizada pela ativação sistêmica da coagulação sanguínea, levando à trombose microvascular difusa e podendo comprometer a função de múltiplos órgãos. O acelerado consumo de plaquetas e fatores de coagulação pode, no entanto, dar origem a um estado de hipocoagulabilidade, o que confere à CID uma característica paradoxal na qual o excesso de coagulação pode causar uma diátese hemorrágica. Doenças que levam à Síndrome de Resposta Inflamatória Sistêmica (SIRS) estão entre os principais gatilhos da CID. A pancreatite é uma dessas doen
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Luo, Karen Yao. "Assessment of the Effect of Induced Hypothermia in Experimental Sepsis Using a Cecal Ligation and Perforation Mouse Model." Thèse, Université d'Ottawa / University of Ottawa, 2011. http://hdl.handle.net/10393/20119.

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Sepsis-induced organ failure is associated with high morbidity and mortality rates. The onset of an exaggerated host response to microbial invasion and/or trauma, is believed to be the primary cause of excessive inflammation and the subsequent tissue hypoperfusion observed in patients with severe sepsis. In our mouse model of sepsis induced by cecal ligation and perforation (CLP), symptoms indicative of the disease, including diarrhea, increased ventilation and persistent hypothermia, are present at six hours after the surgery (T6). In the untreated CLP mice, mortality occurs starting at T15
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Alves, Maxley Martins. "INFLUÊNCIA DO SORO LÁTEX NATURAL DA SERINGUEIRA Hevea Brasiliensis SOBRE A RESPOSTA INFLAMATÓRIA AGUDA INDUZIDA POR SEPSE: ESTUDO EXPERIMENTAL EM RATOS." Pontifícia Universidade Católica de Goiás, 2014. http://localhost:8080/tede/handle/tede/2985.

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Made available in DSpace on 2016-08-10T10:54:27Z (GMT). No. of bitstreams: 1 MAXLEY MARTINS ALVES.pdf: 10774103 bytes, checksum: d2c2ae244a11db0a98fe9c83ada4e1c8 (MD5) Previous issue date: 2014-09-03<br>The acute inflammatory answer is a manifestation of the organism triggered by an infectious or non-infectious taunting. Predisposal factors are, for instance: bacteria, viruses, amongst other microorganisms or traumas. It is an internal survival mechanism. The development of a cascade of immunological events in an attempt of destroying an aggressive agent, with cardiologic, hemodynamic, respi
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Geerken, Luer Christian [Verfasser], and Frank [Akademischer Betreuer] Hildebrand. "Effekte des Interleukin-6 im Rahmen des Systemic Inflammatory Response Syndrome (SIRS) beim Polytrauma an einem Interleukin-6-knock-out-Modell der Maus / Luer Christian Geerken. Unfallchirurgische Klinik der Medizinischen Hochschule Hannover. Betreuer: Frank Hildebrand." Hannover : Bibliothek der Medizinischen Hochschule Hannover, 2011. http://d-nb.info/1017732655/34.

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Mercke, William L. "Diagnosis of Systemic Inflammation Using Transendothelial Electrical Resistance and Low-Temperature Co-fired Ceramic Materials." UKnowledge, 2013. http://uknowledge.uky.edu/cme_etds/21.

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Systemic inflammation involves a complex array of cytokines that can result in organ dysfunction. Mortality remains high despite the vast amount of research conducted to find an effective biomarker. The cause of systemic inflammation can be broad and non-specific; therefore, this research investigates using transendothelial electrical resistance (TEER) measurements to better define systemic inflammatory response syndrome (SIRS)/sepsis within a patient. Results show a difference in TEER measurements between healthy individuals and SIRS-rated patients. This research also displays correlations be
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30

Sauer, Carlos Roberto de Oliveira 1968. "Avaliação da prevalência da síndrome da resposta inflamatória sistêmica no pós-operatório da cirurgia estética de mama : uma contribuição para os cuidados perioperatórios." [s.n.], 2014. http://repositorio.unicamp.br/jspui/handle/REPOSIP/309374.

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Orientador: Francisco Hideo Aoki<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-26T19:53:42Z (GMT). No. of bitstreams: 1 Sauer_CarlosRobertodeOliveira_M.pdf: 4893312 bytes, checksum: 191dcebcc690c95e22eb505e300a4963 (MD5) Previous issue date: 2014<br>Resumo: Introdução: Síndrome da resposta inflamatória sistêmica (SRIS) é uma situação clínica na qual ocorrem as alterações fisiológicas da sepse, mas que é desencadeada por uma agressão não infecciosa ao organismo. Foi definida em 1991, em consenso internaciona
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Silva, André Augusto Botêga. "Alterações funcionais de mitocondrias hepáticas na tolerância ao lipopolissacarídeo (LPS)." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/5/5164/tde-03012018-110429/.

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O presente estudo tem por objetivo principal avaliar as alterações funcionais precoces de mitocôndrias hepáticas de ratos wistar submetidos ao estímulo de sepse através da técnica de ligadura cecal e punção (cecal ligation and puncture-CLP) e indução de tolerância ao lipopolissacarídeo (LPS) de Escherichia coli. As mitocôndrias exercem papel na alteração do metabolismo celular de pacientes sépticos. Os objetivos do presente trabalho foram: (1) padronizar a técnica de indução a tolerância para ratos wistar com LPS de E. coli (2) avaliar a função mitocondrial fosforilativa e oxidativa; (3) quant
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32

Chevalier, Geoffroy. "Analyse de la variabilité de la fréquence cardiaque en cas de syndrome de réponse inflammatoire fœtale aigu isolé ou associé à une hypoxie : Étude expérimentale chez le foetus de brebis." Electronic Thesis or Diss., Université de Lille (2022-....), 2024. http://www.theses.fr/2024ULILS060.

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Introduction : L'infection foetale avec syndrome de réponse inflammatoire foetale (SRIF) pendant le travail est associée au risque de développer une septicémie néonatale, des troubles du développement neurologique, une paralysie cérébrale, voire un décès. Lorsque l’acidose se surajoute au SRIF pendant le travail, cela induit une situation à très haut risque pour le foetus. Les méthodes actuelles pour diagnostiquer le SRIF sont insuffisantes. Nous avons émis l'hypothèse que l'analyse de la variabilité de la fréquence cardiaque foetale (VFC) pourrait être utilisée pour détecter le SRIF. Par cons
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Arshid, Samina. "Avaliação do efeito do précondicionamento isquêmico no proteoma e fosfoproteoma de neutrófilos de ratos após isquemia/reperfusão." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/5/5132/tde-18012017-142837/.

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Introdução: O trauma é um fenômeno que cursa com lesão tecidual, sendo que o trauma cirúrgico (TC) apresenta a referida lesão como consequência de um ato cirúrgico. A isquemia seguida de reperfusão (IR) é um evento comum em várias condições patológicas, bem como em diversos procedimentos cirúrgicos, principalmente transplantes. É frequente o desenvolvimento de lesões teciduais locais e remotas após trauma e após a I/R, parte de um fenômeno conhecido como síndrome da resposta inflamatória sistêmica (SRIS), frequentemente seguida pela falência de múltiplos órgãos (FMO). Estudos provaram o envolv
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Ferreira, Cesar Augusto. "Efeitos da aprotinina em crianças com cardiopatia congênita acianogênica operadas com circulação extracorpórea." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/17/17137/tde-11042010-210547/.

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Introdução. A Aprotinina parece reduzir o uso de transfusões, o processo inflamatório e o dano miocárdico, pós-CEC. Material e Métodos. Estudo prospectivo randomizado em crianças de 30 dias a 4 anos de idade, submetidas à correção de cardiopatia congênita acianogênica, com CEC e divididas em dois grupos, um denominado Controle (n=9) e o outro, Aprotinina (n=10). Neste, a droga foi administrada imediatamente antes da CEC. A resposta inflamatória sistêmica e disfunções hemostáticas e multiorgânicas foram analisadas por marcadores clínicos e bioquímicos. Foram consideradas significantes as difere
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Albrecht, Madlin [Verfasser], and Ingo [Akademischer Betreuer] Ahrens. "The role of platelet immuno-receptors in patients with acute coronary syndrome and C-reactive protein induced pro-inflammatory gene response in early endothelial progenitor cells = Die Rolle von Plättchen Immuno-Rezeptoren bei Patienten mit akutem Koronarsyndrom und Einfluss von C-reaktivem Protein auf endotheliale Progenitorzellen." Freiburg : Universität, 2014. http://d-nb.info/1123481938/34.

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Islam, Md Hamidul. "Mathematical Modelling of the Inflammatory Response in Coronary Artery Disease." Thesis, Griffith University, 2017. http://hdl.handle.net/10072/365469.

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Atherosclerosis is a condition whereby fatty material is deposited in the walls of arteries resulting in a thickening of the wall. It is the leading cause of morbidity and mortality in much of the world, including Australia. Some of the clinical manifestations of atherosclerosis include acute ischaemic syndromes such as heart attacks and strokes. Despite continuous eorts over the past four decades, the biology of atherosclerosis and its clinical manifestations are still poorly understood. According to the response-to-injury hypothesis, this disease is initiated by an injury to or dysfunctional
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Rocha, Tais Sica da. "Marcadores de síndrome da resposta inflamatória sistêmica e sepse no pós-operatório de cirurgia cardíaca em crianças." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2012. http://hdl.handle.net/10183/77225.

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Objetivo geral: estudar a síndrome da resposta inflamatória sistêmica após a cirurgia cardíaca com circulação extracorpórea (CEC) e a sua relação com marcadores inflamatórios. Objetivos específicos: 1) avaliar a prevalência de síndrome da resposta inflamatória sistêmica (SIRS), sepse e disfunção de múltiplos órgãos (DMO); 2) avaliar a relação da SIRS, sepse e DMO com certos biomarcadores; 3) avaliar a relação desses biomarcadores com mortalidade no pós-operatório de cirurgia cardíaca com CEC em crianças; 4) estudar a cinética do soluble triggering receptor on myeloid cells-1 (sTREM-1), procalc
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Suppa, Alessandra Paes. "Estudo da expressão dos genes regulatórios de hipóxia durante a inflamação pulmonar produzida pela isquemia e reperfusão intestinal em camundongos AIRmax e AIRmin." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/87/87131/tde-29042010-103419/.

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Homeostase do O2 é essencial para a sobrevivência e desenvolvimento fisiológico dos organismos. A falta de O2 nos tecidos é um fator subjacente comum na morbidade e mortalidade de situações clínicas como na Síndrome do Desconforto Respiratório Agudo (ARDS). Na retomada da homeostase as células mielóides exercem suas funções especializadas nas áreas de hipóxia. A adaptação destas células nesta condição depende dos produtos do gene HIF-1<font face=\"Symbol\">&#945, fator de transcrição que responde às mudanças de O2. Neste trabalho caracterizamos os mecanismos celulares e moleculares operantes n
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Chimabucuro, Wilson Kohama. "Isquemia mesentérica e reposição do volume intravascular. Estudo comparativo entre duas soluções salinas com diferentes concentrações de cloreto de sódio nos eventos desencadeados pela reperfusão intestinal. Um modelo experimental em ratos." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/5/5159/tde-10062010-143136/.

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A isquemia do intestino delgado ocorre nas oclusões arteriais dos vasos mesentéricos ou associada à baixa perfusão tecidual causada por choque circulatório. Seus efeitos deletérios locais e sistêmicos frequentemente agravam a evolução clínica de muitas doenças. Este estudo experimental investiga como a reposição do volume intravascular utilizando duas soluções salinas com diferentes concentrações de sódio (solução salina fisiológica e solução 7,5% de cloreto de sódio) modifica a resposta inflamatória e o estresse oxidativo causados pela isquemia do intestino delgado. Ratos Wistar, machos, peso
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Carvalho, Luiz Sérgio Fernandes de 1986. "Influência da lipoproteína de alta densidade (HDL) e de seu metabolismo intravascular sobre a resposta inflamatória e função endotelial na fase aguda do infarto do miocárdio." [s.n.], 2015. http://repositorio.unicamp.br/jspui/handle/REPOSIP/312490.

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Orientadores: Andrei Carvalho Sposito, Valéria Nasser Figueiredo<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-26T20:27:16Z (GMT). No. of bitstreams: 1 Carvalho_LuizSergioFernandesde_D.pdf: 19288751 bytes, checksum: ea3c4fda36c00d542fbe2d8c4f4242e8 (MD5) Previous issue date: 2015<br>Resumo: Introdução: A resposta de fase aguda (RFA) transforma a lipoproteína de alta densidade (HDL) em uma partícula disfuncional que pode favorecer o estresse oxidativo/inflamatório e disfunção da enzima óxido nítrico sintase endote
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Rosario, Andre Loureiro. "Efeito da ressuscitação volêmica precoce na resposta inflamatória e no estresse oxidativo cardiovascular do choque séptico experimental." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/5/5160/tde-01122014-113948/.

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Os mecanismos fisiopatológicos associados aos efeitos benéficos da reanimação guiada pela saturação venosa mista de oxigênio (SvO2) durante a sepse não são claros. Nosso objetivo foi avaliar os efeitos de um algoritmo de reanimação guiado pela SvO2 incluindo fluidos, noradrenalina e dobutamina na hemodinâmica, resposta inflamatória e estresse oxidativo cardiovascular durante um modelo experimental que se assemelha clinicamente ao choque séptico. Dezoito porcos anestesiados e cateterizados (35-45 kg) foram submetidos à peritonite por inoculação fecal (0,75 g/Kg). Depois de permanecerem hipotens
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Beppler, Jaqueline. "Identificação de peptídeos de Escherichia coli capazes de inibir a própria fagocitose em sepse." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/5/5164/tde-06062016-084247/.

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Introdução: Sepse é uma síndrome complexa definida por resposta inflamatória sistêmica, de origem infecciosa e caracterizada por manifestações múltiplas que podem determinar disfunção ou falência de um ou mais órgãos ou sistemas. É a principal causa de morte em unidades de terapia intensiva em pacientes críticos e tem representado uma fonte constante de preocupação para os sistemas de saúde em todo o mundo, devido, principalmente, às taxas elevadas de morbimortalidade. O tratamento da sepse é um desafio e continua a ser uma tarefa difícil devido a inúmeros fatores interferentes. Um estudo do n
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Garib, Ricardo Alexandre. "Efeito da administração parenteral de glutamina sobre a modulação da resposta inflamatória sistêmica, morbidade e mortalidade de ratos submetidos à pancreatite aguda." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/5/5168/tde-21012016-154946/.

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INTRODUÇÃO: Relatos conflitantes têm dificultado para se estabelecer o potencial benefício da glutamina (GLN) no tratamento de condições inflamatórias agudas. Nós avaliamos o efeito da infusão parenteral de GLN, prévia à pancreatite aguda (PA) experimental, nos mediadores inflamatórios, morbidade e mortalidade. MÉTODOS: Ratos Lewis (n = 131) receberam glutamina parenteral (grupo GG), solução salina (grupo SS ou controle), ou permaneceram sem infusão parenteral (grupo Sham) por 48h. Após este período, foi induzida PA por meio da injecção retrógrada de taurocolato de sódio no ducto pancreático.
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Gürsoy, Dilek. "Die Bedeutung des Gerinnungs- und Komplementsystems bei der Ausbildung eines "systemic inflammatory response syndroms" (SIRS) nach Eingriffen mit Hilfe extrakorporaler Zirkulation (EKZ) /." Düsseldorf, 2008. http://opac.nebis.ch/cgi-bin/showAbstract.pl?sys=000254035.

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Georgieff, Roland. "Untersuchungen zum Verlauf von hämodynamischen und gasanalytischen Parametern während der isolierten hyperthermen Extremitätenperfusion mit Tumornekrosefaktor Alpha und Melphalan." Doctoral thesis, Humboldt-Universität zu Berlin, Medizinische Fakultät - Universitätsklinikum Charité, 2004. http://dx.doi.org/10.18452/15068.

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Fragestellung: Es wird untersucht, ob die isolierte hypertherme Extremitätenperfusion (ILP) mit TNF-alpha und Melphalan eine akute systemische inflammatorische Reaktion (SIRS) auslöst. Weiterhin soll der Einfluß von zwei verschiedenen total intravenösen Narkoseverfahren sowie der Zusammenhang der unabhängig voneinander bestimmten Meßgrößen Herzindex/Sauerstoffverbrauchsindex (HI/VO2I) und Sauerstoffverbrauchsindex/Sauerstoffangebotsindex (VO2I/DO2I) beim Entstehen eines SIRS analysiert werden. Methodik: 73 Patienten, die sich einer ILP mit TNF-alpha und Melphalan in Allgemeinanästhesie unterz
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Hassen, Tiffany Alicia. "Systemic inflammatory response syndrome and sepsis in major vascular surgery." Thesis, 2006. http://hdl.handle.net/2440/69444.

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This study aimed to identify relationships between post-operative systemic inflammatory response syndrome (SIRS) and sepsis, and markers of immunological, neuroendocrine, nutritional and psychological status ; to examine relationships between psychological variables and neuroendocrine responses to surgery; and to identify differences in immunological and neuroendocrine responses to open abdominal aortic aneurysm (AAA) repair compared with endovascular aneurysm repair (EVAR). It was concluded that higher pre-operative CD11b may be associated with more severe SIRS following major vascular surger
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Bien, Mauo-Ying, and 邊苗瑛. "Breathing Pattern Variability in Patients with Systemic Inflammatory Response Syndrome or Persistent Vegetative State." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/79825846055512767205.

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博士<br>國立陽明大學<br>生理學研究所<br>92<br>The breathing pattern in normal subjects displays a certain variability, which is maintained by a central neural mechanism, feedback loops of arterial chemoreceptors and lung vagal sensory receptors, and cortical influences. Deviations in breathing pattern variability from the normal level have been found in individuals in pathological conditions. Quantitative methods, including calculations of coefficients of variation, the Poincaré plot, and the spectral analysis have been applied to analyze the breathing pattern variability to serve as indicators of pathoph
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Niu, Shuo. "Regulation Of Innate Immune Cell Response Under Sub-acute/Chronic Inflammatory Conditions." 2017. http://scholarworks.gsu.edu/biology_diss/191.

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Sub-acute/chronic inflammatory diseases are often associated with altered inflammatory response, leading to increased host vulnerability to secondary inflammatory challenges. In the first study, by employing streptozotocin (STZ)-induced diabetes in mice, we further investigate mechanisms leading to enhanced polymorphonuclear leukocytes (PMN) response under hyperglycemia. We show that existence of a proinflammatory state associated with broad increases of macrophages in various organs plays a dominant role in promoting PMN response in diabetic mice. Studies of PMN infiltration during zymosan-in
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Peng, Chia-Lin, and 彭佳琳. "Sea Buckthron Leave extracts decrease Lipopolysaccharide-Induced systemic inflammatory response syndrome in C57BL/6 Mice." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/39529333189384927727.

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碩士<br>中山醫學大學<br>營養學研究所<br>102<br>Systemic inflammatory response syndrome (SIRS)is a serious and fatal disease in clinic. Lipopolysaccharide (LPS), derived from the cell wall of gram-negative bacteria, can induce a series of physiological or pathological changes resulting in septic shock and cause multiple organ dysfunctions. LPS-mediated endotoxinas well as a number of catabolic factors can cause severe inflammation and eventually lead to septic shock.Studies have shown that reactive oxygen species (ROS) is overproduced by the stimulation of LPS, and directly implicated as the second messenger
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Pevec, Till [Verfasser]. "Dexamethason-21-isonicotinat als Begleittherapie bei Kühen mit Systemic Inflammatory Response Syndrome / eingereicht von Till Pevec." 2007. http://d-nb.info/986797782/34.

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