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1

Dennis, Kevin. "A mathematical model to describe haemophilus influenzae type B within Western Australia." Thesis, Edith Cowan University, Research Online, Perth, Western Australia, 1995. https://ro.ecu.edu.au/theses/1160.

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This work is primarily aimed at determining the effect that an immunisation policy Is likely to have on the incidence of Haemophllus influenzae Type B (HIB) and systematic HIB in Western Australia. There was a significant effort made to collect data pertinent to the estimation of parameter values but since HIB has only been a notifiable disease since 1992, there was a distinct lack of relevant data available. Private communication with individual’s such as Dr Jeffrey Hanna and Dr Beryl Wild resulted in practical information being obtained that was used to estimate certain parameters. The deter
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2

Fiedler, Lindsey J. "Evolutionary Dynamics of Influenza Type B in the Presence of Vaccination: An Ecological Study." Scholar Commons, 2019. https://scholarcommons.usf.edu/etd/7786.

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Understanding the evolutionary dynamics of influenza type B in human hosts is a public health concern as we strive to minimize the disease burden in seasonal epidemics. Vaccination is considered the best defense against contracting influenza, and everyone over the age of 6 months is advised to get vaccinated before each season. The effect that vaccine-acquired immunity has on the evolution of influenza B remains unclear. In the U.S., vaccine-uptake is irregular across the states, and the differing coverages present an opportunity to study how vaccination influences viral evolution. This thesis
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3

Tissot, Alice. "Caractérisation Structurale et Biochimique de la Nucléoprotéine des virus grippaux de type A, B et D." Thesis, Université Grenoble Alpes (ComUE), 2017. http://www.theses.fr/2017GREAV014/document.

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Le virus de la grippe est un virus à ARN négatif appartenant à la famille des Orthomyxoviridae qui se compose de 7 membres dont les virus influenza A, B, C et D. Le génome viral comprend 7 à 8 particules ribonucléoprotéiques (RNP) au sein desquelles l’ARN viral (ARNv) est recouvert de multiples copies de nucléoprotéines (NP) et est associé à l’ARN polymérase virale via ses extrémités 3’ et 5’. Au cours de ce travail de thèse, nous nous sommes tout d’abord focalisés sur l’étude biochimique de NP A et NP B et avons pu mettre en évidence des comportements différents en ce qui concerne leurs propr
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4

Gravel, Emilie. "Hepsine et matriptase activent l’hémagglutinine des virus influenza A et B et leur inhibition représente une nouvelle stratégie thérapeutique n’entraînant pas le développement de résistance." Mémoire, Université de Sherbrooke, 2016. http://hdl.handle.net/11143/9464.

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Résumé: Chaque année, les épidémies saisonnières d’influenza causent de 3 à 5 millions de cas sévères de maladie, entraînant entre 250 000 et 500 000 décès mondialement. Seulement deux classes d’antiviraux sont actuellement commercialisées pour traiter cette infection respiratoire : les inhibiteurs de la neuraminidase, tels que l’oseltamivir (Tamiflu) et les inhibiteurs du canal ionique M2 (adamantanes). Toutefois, leur utilisation est limitée par l’apparition rapide de résistance virale. Il est donc d’un grand intérêt de développer de nouvelles stratégies thérapeutiques pour le traitement de
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5

Bidard, Isabelle. "Le vaccin anti-"Haemophilus influenzae" type b." Paris 5, 1994. http://www.theses.fr/1994PA05P075.

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6

Parsons, Tina. "Receptor-mediated iron and haem transport in Haemophilus." Thesis, University of Nottingham, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.282581.

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7

Kalies, Helen. "Invasive Haemophilus influenzae type b disease in German children." Diss., lmu, 2007. http://nbn-resolving.de/urn:nbn:de:bvb:19-65220.

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8

Barbour, Marina Louise. "Conjugate vaccine and carriage of Haemophilus influenzae type b." Thesis, University of Oxford, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.358581.

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9

PYNEEANDEE, LE GALL ANNICK. "Vaccination contre haemophilus influenzae de type b : etude dans les bouches-du-rhone." Aix-Marseille 2, 1994. http://www.theses.fr/1994AIX20049.

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10

Coen, Pietro G. "Mathematical models of Haemophilus influenzae type b and Neisseria meningitidis." Thesis, University of Oxford, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.298260.

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11

Brophy, Lisa. "The molecular biology of capsulation of Haemophilus influenzae type b." Thesis, University of Oxford, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.260718.

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12

Kodituwakku, Aruna Poojitha. "Antigen specific B cells in the immune response to Haemophilus influenzae type b PRP conjugate vaccine /." Title page, table of contents and summary only, 2004. http://web4.library.adelaide.edu.au/theses/09PH/09phk769.pdf.

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13

Lorthiois, Ana Paula de Almeida Aranha. "Desenvolvimento de processo para obtenção do método de conjugação do polissacarídeo capsular de Haemophilus influenzae tipo b com toxóide tetânico." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/87/87131/tde-05012009-132129/.

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Haemophilus influenzae type b (Hib) é uma importante bactéria Gram-negativa causadora de pneumonia, meningite e septicemia em crianças abaixo dos 5 anos de idade. A prevenção contra a doença pode ser alcançada pela imunização da população com vacina conjugada polissacarídeo-proteína, uma vez que a vacina de polissacarídeo não é eficiente. As vacinas conjugadas disponíveis comercialmente custam para o governo brasileiro cerca de US2,7 a dose, sendo necessárias no mínimo 3 doses para imunização completa. O presente estudo desenvolveu um novo método de conjugação de polissacarídeo capsular de Hib
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14

Miranzi, Sybelle de Souza Castro. "Análise de tendência temporal: uma alternativa para avaliação do impacto da vacinação contra Haemophilus influenzae tipo b, no Brasil." Universidade de São Paulo, 2004. http://www.teses.usp.br/teses/disponiveis/22/22133/tde-18122007-153143/.

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As meningites representam um importante agravo no quadro sanitário nacional, por suas características epidemiológicas e por seu impacto sócio-econômico. O Haemophilus influenzae tipo b (HIB), causa infecções respiratórias e doenças invasivas como meningites, pneumonias, epiglotites, sinusites, bacteremias, otites e artrites. Entre essas enfermidades, a meningite tem sido a mais estudada, em virtude de sua alta morbi-mortalidade e por ser de notificação compulsória. A proposta deste trabalho foi a de avaliar a tendência, em série histórica, da morbimortalidade e da letalidade das meningites cau
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15

Patel, Alpesh. "Purification and crystallization of recombinant porins from Haemophilus influenzae type B." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0017/MQ55084.pdf.

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16

Vachon, Vincent. "The permeability of the outer membrane of Haemophilus influenzae type b /." Thesis, McGill University, 1987. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=75369.

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Phospholipids and lipopolysaccharide were purified from Haemophilus influenzae type b and combined by sonication to form liposomes which were impermeable to sucrose and to high molecular weight polysaccharides. When outer membrane proteins were incorporated into such liposomes, they became permeable to saccharides up to a molecular weight of about 1,400 daltons. The outer membrane proteins were fractionated on DEAE-Sepharose. Three protein-containing peaks were eluted from the column. Two of these peaks contained mixtures of proteins while the third peak contained only a single species of prot
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17

Le, hir Jerome. "Compréhension du métabolisme cellulaire et de la synthèse du polyoside capsulaire chez Haemophilus influenzae de type b." Thesis, Toulouse, INSA, 2012. http://www.theses.fr/2012ISAT0013.

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Réalisé au sein du LISBP (Laboratoire d’Ingénierie des Systèmes Biologiques et des Procédés, INSA Toulouse), ce travail porte sur l’étude du germe pathogène Haemophilus influenzae de type b (Hib). L’objectif du travail est l’amélioration de la compréhension du métabolisme cellulaire et de la synthèse du polyoside capsulaire chez Hib, utilisé pour la fabrication du vaccin. Ainsi, une étude bibliographique associée à une analyse in silico et à une démarche expérimentale rationnelle a permis de développer un milieu chimiquement défini répondant aux critères de robustesse du procédé et de qualité
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18

Rodrigues, Elô de Oliveira. "Elaboração de material de referência in house para vacina contra Hib e produtos intermediários: uma proposta para normalização de testes físico-químicos do controle de qualidade." Instituto de Tecnologia em Imunobiológicos, 2009. https://www.arca.fiocruz.br/handle/icict/5860.

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Submitted by Priscila Nascimento (pnascimento@icict.fiocruz.br) on 2012-11-23T15:50:27Z No. of bitstreams: 1 elo-de-oliveira-rodrigues.pdf: 697936 bytes, checksum: fb3899c2c6d659498d8e8ab0a1a0b33a (MD5)<br>Made available in DSpace on 2012-11-23T15:50:27Z (GMT). No. of bitstreams: 1 elo-de-oliveira-rodrigues.pdf: 697936 bytes, checksum: fb3899c2c6d659498d8e8ab0a1a0b33a (MD5) Previous issue date: 2009<br>Fundação Oswaldo Cruz. Instituto de Tecnologia em Imunobiológicos. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.<br>O Instituto de
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19

Lyew, Darwin J. "The exclusion limit of the outer membrane of Haemophilus influenzae type b /." Thesis, McGill University, 1985. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=63292.

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20

Barra, Anne. "Etude des anticorps humains anti-polyoside capsulaire (prp) d'haemophilus influenzae type b." Poitiers, 1990. http://www.theses.fr/1990POIT2337.

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L'haemophilus influenzae de type b est responsable d'un grand nombre d'infections systemiques, notamment chez l'enfant de moins de 5 ans. Leur severite potentielle a conduit a rechercher une protection active par vaccination. Le polyoside capsulaire polyribosylribitolphosphate (prp) est l'antigene majeur et le principal facteur de virulence. Il induit la production d'anticorps mais est peu immunogene chez l'enfant avant 24 mois et chez des sujets presentant un terrain particulier (deficits immunitaires ou drepanocytose, par exemple). Nous avons etudie les anticorps seriques acquis spontanement
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21

Dahan, David. "Biophysics of porin, the major outer membrane protein of Haemophilus influenzae type b." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape16/PQDD_0025/NQ29916.pdf.

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22

Srikumar, Ramakrishnan. "Topology of porin, the major outer membrane protein of Haemophilus influenzae type b." Thesis, McGill University, 1995. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=40261.

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Haemophilus influenzae type b (Hib) is a Gram-negative bacterium that causes meningitis in infants. A protein called porin of 341 amino acids, M$ rm sb{r}$ 37,782 daltons, is located in the outer membrane of Hib and allows for the diffusion into the periplasmic space of small solutes up to a molecular mass of 1400 daltons.<br>Based on parameters of hydrophilicity and amphiphilicity a model for Hib porin was generated. The model proposed an organization of sixteen anti-parallel $ beta$-strands that traverse the outer membrane, eight long loops that connect the $ beta$-strands on one side and sh
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23

Chan, Chun Kong Laval. "Syntheses of oligomers of the capsular polysaccharide of Haemophilus influenzae type b bacteria." Thesis, McGill University, 1989. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=75949.

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A new approach to the ribosyl-ribitol unit of the capsular polysaccharide of Haemophilus influenzae type b (Hib) was developed. Oligomers (n = 1-5) of the polysaccharide attached to a ribose spacer were synthesized. These compounds have potential use as a synthetic vaccine component for immunization against Hib meningitis.<br>An attempt to synthesize fragments of Escherichia coli K100 bacteria polysaccharide which is cross-reactive with the Hib polysaccharide was made.<br>In connection with the synthesis of Goniothalenol, a new protecting group, the $p,p sp prime$-dinitrobenzhydryl ether was d
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24

Dahan, David. "Biophysics of porin : the major outer membrane protein of Haemophilus influenzae type b." Thesis, McGill University, 1996. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=42009.

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Haemophilus influenzae type b (Hib) is a Gram-negative bacterium that causes meningitis in infants. Located in the outer membrane, Hib porin (342 amino acids, M$ rm sb{r}$ 37,782 daltons) forms channels that allow for the diffusion into the periplasm of small solutes up to a molecular mass of 1400 daltons.<br>Based on predictions of porin secondary structure, a model of Hib porin was generated. The model proposed sixteen membrane spanning $ beta$-strands connected by eight long loops on one side and eight short $ beta$-turns on the other side. To refine further this model, the epitopes of nine
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25

Cardoso, Elaine Cristina. "Avaliação da transferência materno-infantil de anticorpos séricos e secretores dirigidos ao polissacarídeo da cápsula de Haemophilus influenzae tipo B (HIB) em amostras pré e pós-vacinais de mães com PRP conjugado ao toxóide tetânico (PRP-T)." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/42/42133/tde-17092008-112422/.

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Introdução: O Haemophilus influenzae type b (Hib) é a primeira maior causa de meningites e pneumonias provocadas por bactérias encapsuladas. Trabalhos revelam que anticorpos maternos, séricos e secretores, podem proteger recém nascidos (RN) destes patógenos encapsulados e contribuem para a maturação do sistema imune do infante. Objetivo: O presente estudo teve como objetivo investigar a transferência materno-infantil de anticorpos anti-Hib em mães vacinadas e que não receberam a vacina anti-Hib. Materiais e Métodos: Nós avaliamos 29 mulheres saudáveis, das quais 13 foram vacinadas e 16 não rec
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26

Wang, Zhi Yuan. "Total synthesis of methyl 8(S)-, 9(S)-, 11(S)- and 12(S)- hydroxyeicosatetraenoates & of oligosaccharides from Haemophilus influenzae type B." Thesis, McGill University, 1987. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=75423.

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A general approach to the asymmetric syntheses of HETEs in both enantiomeric forms was developed. The syntheses of 8(S)-, 9(S)-, 11(S)- and 12(S)-HETE methyl esters, starting from D-arabinose, were accomplished.<br>A practical approach to the solution synthesis of fragments from Haemophilus influenzae type b capsular polymer was established, which opens a route to the development of a new vaccine against meningitis. The major aspects of this approach, stereocontrolled glycosidation, selective protection and deprotection, and efficient phosphorylation were detailed. The normal solution synthese
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27

Behr, Heinrich Richard. "The development of physico-chemical quality control methods for Haemophilus influenzae type b vaccine production." Master's thesis, University of Cape Town, 2013. http://hdl.handle.net/11427/6581.

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The development of a low cost Haemophilus influenzaetype b (Hib) manufacturing platform at The Biovac Institute (TBI) required analytical method development in parallel with the production process development. Technology transfer enabled TBI to develop Hib vaccine production which could lead to the development of vaccine manufacturing capacity in subSaharan Africa. Initial studies were conducted in the Research and Development (R&D) department from where the process was transferred to the Good Manufacturing Process (GMP) environments of the Production and Quality Control departments respective
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28

Geiger, Stephanie. "Influence of the expression of mutated B-type lamins on nuclear architecture and function." [S.l. : s.n.], 2007. http://nbn-resolving.de/urn:nbn:de:bsz:16-opus-83247.

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29

Karlström, Patric. "Heart failure : biomarker effect and influence on quality of life." Doctoral thesis, Linköpings universitet, Avdelningen för kardiovaskulär medicin, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-124560.

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Background and aims: Heart failure (HF) is a life threatening condition and optimal handling is necessary to reduce risk of therapy failure. The aims of this thesis were: (Paper I) to examine whether BNP (B-type natriuretic peptide)-guided HF treatment improves morbidity and mortality when compared with HF therapy implemented by a treating physician at sites experienced in managing patients with HF according to guidelines; (Paper II) to investigate how to define a responder regarding optimal cut-off level of BNP to predict death, need for hospitalisation, and worsening HF and to determine the
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30

PREZIOSI, MARIE-PIERRE. "Prevention des infections a haemophilus influenzae de type b par la vaccination : etude de 400 nourrissons vaccines par le polyoside capsulaire couple a la proteine tetanique." Lyon 1, 1990. http://www.theses.fr/1990LYO1M044.

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31

Albani, Silvia Maria Ferreira. "Métodos alternativos de purificação do polissacarídeo capsular de Haemophilus influenzae tipo b." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/87/87131/tde-17042009-174554/.

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Haemophilus influenzae tipo b é uma bactéria Gram-negativa, patogênica causadora de meningites em crianças. A cápsula polissacarídica (PSb) é o principal fator de virulência e é usado como antígeno vacinal. O método clássico de purificação do PSb envolve várias etapas de precipitação com etanol, fenol e detergente catiônico (inflamável, corrosivo e tóxico), e etapas de ultracentrifugação. O objetivo deste estudo foi substituir total ou parcial as precipitações e/ou uso das centrífugas por cromatografia, digestão enzimática, microfiltração e ultrafiltração tangencial. As cromatografias de troca
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32

McVernon, Jodie. "Evaluation of the continuing effectiveness of the United Kingdom's Haemophilus influenzae type b national immunisation programme." Thesis, Open University, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.409553.

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33

Griffiths, Ulla Kou. "Haemophilus influenzae type b vaccine in low- and middle-income countries : impact, costs and incremental cost-utility." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2012. http://researchonline.lshtm.ac.uk/2869500/.

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Haemophilus influenzae type b (Hib) is an infectious bacterium transmitted from person to person through close contact. Hib can cause meningitis, pneumonia and a number of rarer forms of disease, primarily in children less than five years. Hib conjugate vaccines became available during the early 1990s and high-income countries quickly introduced this vaccine into their routine programmes and have now achieved a near disappearance of Hib disease. However, relatively high vaccine prices and uncertainties about Hib disease burden led to a slow uptake in low- and middle-income countries. The aim o
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34

Trück, Johannes. "B cell response to pneumococcal vaccines." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:4bbccd8c-febd-4713-a97b-d6a8a08e3979.

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Streptococcus pneumoniae is a significant cause of mortality and morbidity in both children and older adults, with infection resulting in invasive disease, pneumonia and otitis media. The inclusion of pneumococcal conjugate vaccines in routine infant immunisation programmes has had a major impact on disease rates. Vaccine-induced protection against pneumococcal infection is thought to be mediated by the generation of persistent serotype-specific functional antibodies and antigen-specific memory B cells, the latter capable of generating a rapid secondary antibody response on re-exposure to anti
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Palmigiani, Ana Lucia Martins de Luna. "Avaliação das incertezas de medições analíticas em implementação de um modelo de controle." Instituto de Tecnologia em Imunobiológicos, 2005. https://www.arca.fiocruz.br/handle/icict/5760.

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Submitted by Priscila Nascimento (pnascimento@icict.fiocruz.br) on 2012-11-08T17:19:50Z No. of bitstreams: 1 01d.pdf: 1587828 bytes, checksum: 1a8694d38c20b5c410d6e957fd6a2575 (MD5)<br>Made available in DSpace on 2012-11-08T17:19:50Z (GMT). No. of bitstreams: 1 01d.pdf: 1587828 bytes, checksum: 1a8694d38c20b5c410d6e957fd6a2575 (MD5) Previous issue date: 2005-06<br>Fundação Oswaldo Cruz. Instituto de Tecnologia em Imunobiológicos. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.<br>O objetivo deste trabalho foi aprimorar a qualidadean
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Renard, Delphine Grimprel Emmanuel. "Méningite à Haemophilus influenzae de type b chez l'enfant étude de 13 cas, enfants ayant reçu au moins 1 injection du vaccin anti-Haemophilus influenzae b, entre janvier 2001 et juin 2005 /." Créteil : Université de Paris-Val-de-Marne, 2006. http://doxa.scd.univ-paris12.fr:80/theses/th0237246.pdf.

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37

Goddard, Elizabeth Anne. "IgG subclasses, specific antibodies and immunoglobulin allotypes in children with invasive Haemophilus influenzae type B and Staphylococcus aureus infections." Doctoral thesis, University of Cape Town, 1994. http://hdl.handle.net/11427/27003.

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OBJECTIVE: The principal objective of this study was to measure various aspects of immunity in children with invasive infections due to Haemophilus influenzae type b and Staphylococcus aureus. These serious infections are a significant cause of childhood morbidity and mortality in all populations and affect healthy as well as compromised children. Evidence suggests that imbalances or deficiencies in certain aspects of immunity such as IgG subclasses, the capacity to make specific subclass antibodies, antibody affinities, complement isotypes, immunoglobulin allotypes or mannose binding protein
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38

Cuperus, Florence Silvie. "Influence of UV-B radiation on quality determining compounds in must and wine and suspension cell cultures of Vitis vinifera /." Zürich : ETH, 2007. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=16974.

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39

Balzano-Foucher, Marielle. "Influence du microenvironnement stromal de la moelle osseuse sur le développement des lymphocytes B normaux et pathologiques." Thesis, Aix-Marseille, 2016. http://www.theses.fr/2016AIXM4048.

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Chez l’adulte les premières étapes du développement hématopoïétique se déroulent dans la moelle osseuse (MO). La contribution de cellules d’origine mésenchymateuse, appelées niches stromales, a été démontrée dans le cas de la maintenance des cellules souches hématopoïétiques (CSH) et du développement des lymphocytes B (LB). Ainsi la maintenance des CSH dépend de niches périvasculaires sécrétant CXCL12 et SCF. Par ailleurs les LB les plus précoces (preproB) sont en contact de cellules stromales CXCL12+, puis migrent vers des cellules stromales exprimant l’interleukine-7 lors de leur différentia
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40

Williamson, Nancy Jean. "Evaluation of risk factors associated with diminished immune response to Haemophilus influenzae type b PRP-D vaccine among Inuit infants of the Northwest Territories." Thesis, University of Ottawa (Canada), 1994. http://hdl.handle.net/10393/10081.

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Haemophilus influenzae type b (Hib) is the most important cause of serious invasive bacterial disease in young children in many countries, particularly industrialized countries. A 1986 study using PRP-D vaccine among Aboriginal infants in the Northwest Territories (N.W.T.) reported that all ethnic groups responded poorly, but the proportion of Inuit (44%) who responded with protective anti-PRP antibody levels of $\geq0.15\ \mu$/mL was smaller than that of the Dene (60%). This study was undertaken to explore possible reasons for the poorer results of the Inuit infants. Results. The results sugg
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41

Silva, Mateus Ribeiro da. "Estratégias de cultivo para a produção de polissacarídeo capsular por Haemophilus influenzae tipo b e determinação de parâmetros de qualidade para o produto." Universidade Federal de São Carlos, 2010. https://repositorio.ufscar.br/handle/ufscar/6967.

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Made available in DSpace on 2016-08-17T18:39:34Z (GMT). No. of bitstreams: 1 3277.pdf: 7015864 bytes, checksum: 9834075e819d2bb62213cf25d21ce5e5 (MD5) Previous issue date: 2010-08-27<br>Haemophilus influenzae type b (Hib) is a Gram negative bacterium responsible for causing meningitis worldwide. The capsular polysaccharide b, a polymer composed by repeating units of ribosyl-ribitol phosphate (PRP), is the major virulence factor and it is used in the formulation of the vaccine against this microorganism. Despite their high efficiency, the conjugated vaccine against Hib is a product of high pr
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Cavalcante, Rejane Silva [UNIFESP]. "Capacitação de profissionais da saúde no componente peri-neonatal da atenção integrada às doenças prevalentes na infância: conhecimento e percepção de mudança na prática clínica em região Amazônica." Universidade Federal de São Paulo (UNIFESP), 2010. http://repositorio.unifesp.br/handle/11600/9158.

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Made available in DSpace on 2015-07-22T20:49:40Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-06-30<br>Introdução: Apesar de relatos sobre a Atenção Integrada às Doenças Prevalentes na Infância (AIDPI) melhorar a assistência à saúde da criança até cinco anos, não são identificados estudos direcionados ao componente peri-neonatal dessa estratégia. Objetivo: avaliar, após a capacitação em AIDPI Neonatal, o conhecimento e a percepção de médicos e enfermeiros quanto à assistência à gestante e à criança do nascimento até os dois meses de vida, e sua aplicabilidade prática em uma região
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Jiguet-Jiglaire, Carine. "Influence de la présence d’un mélanome de type b16 sur le recrutement de cellules immunitaires par voie sanguine chez la souris mus musculuse." Toulouse 3, 2006. http://www.theses.fr/2006TOU30261.

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La tumeur est capable d'échapper au système immunitaire. Mes travaux de thèse ont permis de montrer que la tumeur est capable de perturber le recrutement des lymphocytes naïfs au sein d'un ganglion lymphatique drainant une tumeur. Ce défaut de recrutement est corrélé à une diminution de l'expression de la chimiokine CCL21, impliquée dans l'adhésion ferme des lymphocytes à la surface des cellules cuboïdales des High Endothelial Venules, veinules spécialisées dans la capture des lymphocytes. Ce défaut de recrutement des lymphocytes est généralisable à d'autres organes lymphoïdes secondaires. J'a
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Lucas, Valérie. "Influence de la teneur en gallium sur les propriétés des matrices de type alumine B : élaboration, activation par Cr3+, Nd3+, Yb3+, Yb2+ et spectroscopie optique." Paris 6, 1993. http://www.theses.fr/1993PA066600.

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L'objectif de ce travail a ete d'evaluer les potentialites de la methode d'echange ionique pour creer de nouveaux materiaux pour l'optique. Les materiaux synthetises sont des matrices de type alumine beta: aluminates et alumino-gallates de sodium et baryum. Ce sont des conducteurs ioniques pour lesquels il est possible d'echanger les ions alcalins ou alcalino-terreux par des ions luminescents comme les lanthanides: neodyme et ytterbium. Les variations selon la teneur en gallium des parametres cristallins et la localisation des differents ions gallium, aluminium et sodium ont ete etudies par di
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Berrington, Janet Elizabeth. "Haemophilus influenzae type b and tetanus antibody responses in UK infants : effects of the acellular DTPHib combination vaccine, preterm delivery, and a booster dose of PRP-T." Thesis, University of Newcastle upon Tyne, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.413255.

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Moser, Rebekka. "IgG Antiköperbestimmung gegen Haemophilus influenza Typ b, Streptococcus pneumoniae Stereotypen 14 und 19F und Clostridium tetani Toxin in Nabelschnurseren und Seren von 0-6 Monate alten Säuglingen /." [S.l.] : [s.n.], 1998. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.

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Goka, Edward Anthony Chilongo. "Influenza A viruses dual and multiple infections with other respiratory viruses and risk of hospitalization and mortality." Thesis, University of Manchester, 2014. https://www.research.manchester.ac.uk/portal/en/theses/influenza-a-viruses-dual-and-multiple-infections-with-other-respiratory-viruses-and-risk-of-hospitalization-and-mortality(256eb122-a52a-4276-8dc1-28b5a2cc6662).html.

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Introduction: Epidemiological studies have indicated that 5-38% of influenza like illnesses (ILI) develop into severe disease due to, among others, factors such as; underlying chronic diseases, age, pregnancy, and viral mutations. There are suggestions that dual or multiple virus infections may affect disease severity. This study investigated the association between co-infection between influenza A viruses and other respiratory viruses and disease severity. Methodology: Datum for samples from North West England tested between January 2007 and June 2012 was analysed for patterns of co-infection
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Wong, Chiu-Wai, and 黃昭偉. "Retrospective study on Type A and B influenza with bacterial co-infection." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/55238717978998553772.

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碩士<br>中山醫學大學<br>醫學研究所<br>101<br>Background: To review the presentation of type A and B influenza with bacterial co-infection in medical center and describe the epidemiology of co-infection. We also discuss the clinical course, pathogenesis, and rational clinical management of co-infection. Material and method: We retrospectively analyzed the medical records of 1702 influenza-like patients who underwent nasopharyngeal swab, from January 2011 to March 2012, at the medical center of Chung Shan Medical University Hospital. Totally 750 patients were included in this study. Patients were divided in
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Peer, Abdool Kader Cassim. "Microbiology and molecular epidemiology of multiresistant haemophilus influenza type B in Durban, South Africa." Thesis, 1988. http://hdl.handle.net/10413/7610.

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Microbiological and molecular epidemiological studies were conducted on 36 multi-resistant Haemophilus influenzae strains, isolated from paediatric patients, over a 26 month period (April 1986 to May 1988). The majority of strains (80,5%) had been isolated from blood and cerebrospinal fluid. More than 80% of isolates tested belonged to biotype II and 90% were of serotype B. Minimal inhibitory concentrations against 6 antibiotics (ampicillin, chloramphenicol, tetracycline, rifampicin, streptomycin and cefotaxime) confirmed the presence of multi-resistant strains. Resistance to rifampicin was co
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Zmora, Pawel. "Activation of the influenza virus hemagglutinin by type II transmembrane serine proteases." Thesis, 2015. http://hdl.handle.net/11858/00-1735-0000-0028-871A-B.

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