Log in

Relevant bibliographies by topics / Inhibitio / Dissertations / Theses

To see the other types of publications on this topic, follow the link: Inhibitio.

Dissertations / Theses on the topic 'Inhibitio'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 dissertations / theses for your research on the topic 'Inhibitio.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.

1

Bajul, Audrey. "Influence des carboxymethylcelluloses sur la cristallisation des sels tartriques dans les solutions hydroalcooliques et les vins." Thesis, Toulouse, INPT, 2018. http://www.theses.fr/2018INPT0048.

Full text

Abstract:

Un problème majeur de l’industrie vinicole est la difficulté à contrôler la cristallisation des sels tartriques. Ce phénomène confère une image négative chez les consommateurs, en particulier pour les vins effervescents dont l’instabilité tartrique provoque le débordement (ou gerbage) de la bouteille. La cristallisation de ces sels ioniques modifie l’équilibre acido-basique des vins qui influence leurs qualités organoleptiques. Parmi les méthodes de contrôle préventif, l’utilisation de carboxyméthylcellulose (CMC) a été autorisée dans les vins depuis 2009. Les CMC sont des polyélectrolytes que

APA, Harvard, Vancouver, ISO, and other styles

2

Booker, Samuel A. "Inhibiting inhibition : interactions amongst interneurons of the hippocampus." Thesis, University of Glasgow, 2011. http://theses.gla.ac.uk/2995/.

Full text

Abstract:

Cortical networks comprise excitatory principal cells and interneurons (IN); the latter showing large neurochemical, morphological and physiological heterogeneity. GABA release from IN axon terminals activates fast ionotropic GABAA or slow metabotropic GABAB receptors (GABABR); ionotropic GABA mechanisms are well described in INs, whereas GABABR activity is less well understood. The primary aim of this thesis is to ascertain GABABR mediated inhibition in different IN types containing the neurochemicals parvalbumin (PV), cholecystokinin (CCK) or somatostatin (SSt). Using immunocytochemical tech

APA, Harvard, Vancouver, ISO, and other styles

3

Shkirskiy, Viacheslav. "Corrosion inhibition of galvanized steel by LDH - inhibitor hybrids : Mechanisms of Inhibitor Release and Corrosion Reactions." Thesis, Paris 6, 2015. http://www.theses.fr/2015PA066216/document.

Full text

Abstract:

Le travail présenté essaie de comprendre les mécanismes de l’action d’un inhibiteur de corrosion présent dans un revêtement hybride sous forme de pigments intercalés dans les hydroxydes double lamellaires (HDL) pour la protection de l’acier galvanisé. Trois étapes clés ont été choisies pour ce travail : (1) l’identification d’un inhibiteur de corrosion hydrosoluble pour l’acier galvanisé avec une compréhension de sa réactivité, (2) la détermination des facteurs et des mécanismes contrôlant la libération de l’inhibiteur à partir d’HDL et (3) la compréhension des mécanismes de protection dans un

APA, Harvard, Vancouver, ISO, and other styles

4

Rodkey, Elizabeth A. "INHIBITOR RESISTANCE MECHANISMS AND INHIBITOR DESIGN IN ¿¿-LACTAMASES." Case Western Reserve University School of Graduate Studies / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=case1354463033.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Roweth, Harvey George. "Mechanisms of platelet inhibition by the selective serotonin reuptake inhibitor citalopram." Thesis, University of Cambridge, 2018. https://www.repository.cam.ac.uk/handle/1810/275477.

Full text

Abstract:

Background: Selective serotonin reuptake inhibitor (SSRI) antidepressants prevent serotonin (5-HT) uptake by the serotonin transporter (SERT). Since blood platelets express SERT, SSRIs may modify platelet function and the risk of cardiovascular disease. However, the beneficial or adverse effects of SSRIs on arterial thrombosis are poorly characterised and detailed in vitro experimental data is limited. The SSRI citalopram is a racemate, the (S)-isomer being the more potent SERT inhibitor. Although citalopram has been shown to inhibit platelets in vitro, it is unclear whether this is mediated v

APA, Harvard, Vancouver, ISO, and other styles

6

Elfant, David J. "Inhibiting inhibition : GABAergic networks in the CA1 area of the rat hippocampus." Thesis, University of Oxford, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.496867.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

McCready, Tara Lyn. "Inhibition of protein phosphatase-1 by endogenous inhibitor proteins and natural product toxins." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0032/NQ46885.pdf.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Scavone, M. "DOES THE INHIBITION OF P2Y12 INHIBIT THE PRODUCTION OF THROMBOXANE A2 BY PLATELETS?" Doctoral thesis, Università degli Studi di Milano, 2014. http://hdl.handle.net/2434/233989.

Full text

Abstract:

Patients with acute coronary syndromes (ACS) are treated with dual antiplatelet therapy (DAPT), which includes aspirin, an inhibitor of thromboxane A2 (TxA2) production, and an antagonist of the P2Y12 receptor for ADP. Based on the recent observation that P2Y12 antagonists also inhibit the platelet production of TxA2, it has been suggested that patients with ACS might be safely treated with P2Y12 antagonists only. However, the observation that platelets congenitally deficient of P2Y12 synthesize normal amounts of TxA2 contrasts the results obtained with P2Y12 antagonists. To test whether the r

APA, Harvard, Vancouver, ISO, and other styles

9

Moraal, Christina Maria. "The design, synthesis and evaluation of aminocaffeine derivatives as inhibitors of monoamine oxidase B / Moraal C." Thesis, North-West University, 2011. http://hdl.handle.net/10394/7268.

Full text

Abstract:

Monoamine oxidase (MAO) is responsible for dopamine catabolism in the brain and therefore is especially important in the treatment of Parkinson's disease (PD). MAO–B inhibition provides symptomatic relief by indirectly elevating dopamine levels in the PD brain. PD is caused by the loss of dopaminergic neurons in the substantia nigra and the formation of proteinaceous structures in the brain. The cause of idiopathic PD is unknown, but one theory states that reactive oxygen species (ROS), partly derived from the catalytic cycle of MAO, may be to blame for damaging dopaminergic neurons. Since MAO

APA, Harvard, Vancouver, ISO, and other styles

10

Ahmed, Mohamed. "Inhibition of mild steel corrosion in cooling systems by low- and non-toxic corrosion inhibitors." Thesis, University of Manchester, 2017. https://www.research.manchester.ac.uk/portal/en/theses/inhibition-of-mild-steel-corrosion-in-cooling-systems-by-low-and-nontoxic-corrosion-inhibitors(7dc2367d-7352-4ab2-85b1-39b09d6487d8).html.

Full text

Abstract:

The aim of the research in this thesis was to study how environmentally friendly corrosion inhibitors for cooling water systems might be developed and used. Firstly, reduced toxicity inorganic corrosion inhibitors (i.e. nitrite/molybdate) were considered. Secondly, non-toxic inhibitors based on mono and di-basic salts of carboxylic acids were studied systematically as a function of carbon chain length. For nitrite inhibitor alone, a concentration of 7 mM NaNO2 was effective to inhibit carbon steel in chloride media of 10 mM NaCl, while 10 mM nitrite was needed in sulphate media of 3.66 mM Na2S

APA, Harvard, Vancouver, ISO, and other styles

11

Aduri, Dasharatha Radha Krishna Chaitanya. "Mechanistic Studies of Inhibitors of DNA Replication Restart Pathways in Neisseria Gonorrhoeae." University of Dayton / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=dayton1380732786.

Full text

APA, Harvard, Vancouver, ISO, and other styles

12

Horsch, Laura Marie. "Continuity of Behavioral Inhibition in Early Childhood: The Impact of Parental Attitudes toward Socially Inhibited Behavior." Diss., Virginia Tech, 2006. http://hdl.handle.net/10919/77993.

Full text

Abstract:

Although behavioral inhibition has been found to be relatively stable, such stability has not always been shown. Moreover, although an association between parental shyness and child behavioral inhibition has been reported, this relationship is imperfect and indirect. The present study proposed that one factor that may impact these relationships is the attitudes parents hold toward having a shy, inhibited child. Although shyness is typically regarded as a negative and maladaptive trait, it is not necessarily viewed as problematic by all parents. The present study investigated a series of te

APA, Harvard, Vancouver, ISO, and other styles

13

Noma, Naruto. "Inhibition of MMP-2-Mediated Mast Cell Invasion by NF-κB Inhibitor DHMEQ in Mast Cells". 京都大学 (Kyoto University), 2017. http://hdl.handle.net/2433/225446.

Full text

APA, Harvard, Vancouver, ISO, and other styles

14

Tuck, Benjamin. "Investigating Multispecies Biofilms on Steel Surfaces in Seawater and Biofilm Inhibition by a Novel, Multifunctional Inhibitor." Thesis, Curtin University, 2022. http://hdl.handle.net/20.500.11937/89066.

Full text

Abstract:

Biofilm formation is a global, $multi-billion phenomenon spanning a plethora of stakeholders. This thesis investigates critical fundamental aspects of biofilm formation on steel and evaluates the efficacy of a novel, environmentally sustainable and multifunctional inhibitor compound developed through a broader Australian Research Council Discovery Project collaboration. Focused on sustainable and effective biofilm disruption, results from this thesis are used to expand fundamental knowledge and generate a targeted approach to biofilm mitigation that improves biocide function.

APA, Harvard, Vancouver, ISO, and other styles

15

Wang, Hansheng. "Electrochemical investigation of "green" film-forming corrosion inhibitors :." Thesis, KTH, Skolan för kemivetenskap (CHE), 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-40888.

Full text

Abstract:

In this work, a comparative electrochemical study has been performed to evaluate corrosion inhibition property of several film-forming corrosion inhibitors provide by Akzo Nobel on carbon steel in a chloride solution. For carbon steel exposed to 1 M NaCl solution with and without added inhibitor, electrochemical measurements including electrochemical impedance spectroscopy (EIS), linear polarization resistance (LPR) at different exposure time intervals, and potentiodynamic polarization at the termination of the exposure, have been performed to investigate the film forming process and to evalua

APA, Harvard, Vancouver, ISO, and other styles

16

Park, Junguk. "Development of neutral phosphotyrosine memetics as a protein tyrosine phosphatase inhibitor and studies on its inhibition mechanism." Columbus, Ohio : Ohio State University, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1133278132.

Full text

APA, Harvard, Vancouver, ISO, and other styles

17

Pardali, Katerina. "Mechanisms of Regulation of the Cell Cycle Inhibitor p21Waf1/Cip1 in TGF-β-Mediated Cell Growth Inhibition". Doctoral thesis, Uppsala universitet, Ludwiginstitutet för cancerforskning, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5892.

Full text

Abstract:

TGF-β is the founding member of a multifunctional family of cytokines that regulate many aspects of cell physiology, including cell growth, differentiation, motility and death and play important roles in many developmental and pathological processes. TGF-β signals by binding to a heterotetrameric complex of type I and type II serine/threonine kinase receptors. The type I receptor is phosphorylated and activated by the type II receptor and propagates the signal to the nucleus by phosphorylating and activating receptor-regulated Smad proteins (R-Smads). Once activated, the R-Smads translocate to

APA, Harvard, Vancouver, ISO, and other styles

18

Visal, Savita D. "Inhibition of Colorado potato beetle (Leptinotarsa decemlineata Say) digestive proteinases, the search for a broad-spectrum inhibitor." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/NQ36335.pdf.

Full text

APA, Harvard, Vancouver, ISO, and other styles

19

Guan, Hua. "Investigation of wettability effects and non-aqueous scale inhibitor applications during the design of scale inhibition treatments." Thesis, Heriot-Watt University, 2004. http://hdl.handle.net/10399/335.

Full text

APA, Harvard, Vancouver, ISO, and other styles

20

Niwano, Mototaka. "The Inhibition of Tumor Growth and Microvascular Angiogenesis by the Potent Angiogenesis inhibitor, TNP-470 in Rats." Kyoto University, 1998. http://hdl.handle.net/2433/156992.

Full text

Abstract:

本文データは平成22年度国立国会図書館の学位論文(博士)のデジタル化実施により作成された画像ファイルを基にpdf変換したものである<br>Kyoto University (京都大学)<br>0048<br>新制・課程博士<br>博士(医学)<br>甲第7486号<br>医博第2039号<br>新制||医||697(附属図書館)<br>UT51-98-U153<br>京都大学大学院医学研究科分子医学系専攻<br>(主査)教授千葉勉, 教授山岡義生, 教授今村正之<br>学位規則第4条第1項該当

APA, Harvard, Vancouver, ISO, and other styles

21

Kreienbühl, Peter Lukas. "Protein phosphatase inhibitor okadaic acid alters cell shape and F-action distribution and inhibits /." Bern, 1992. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

Estrada, Sergio. "Cystatin A, a mammalian cysteine proteinase inhibitor : mechanism of inhibition of target proteinases by recombinant cystatin A variants /." Uppsala : Swedish Univ. of Agricultural Sciences (Sveriges lantbruksuniv.), 1998. http://epsilon.slu.se/avh/1998/91-576-5448-4.gif.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

Cho, Moonjeong. "Attenuation of Egr-1 induced apoptosis by inhibition of p53 and its implications as potential inhibitor of Alzheimer's Disease." Thesis, McGill University, 2014. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=123316.

Full text

Abstract:

The mechanism in which neurodegeneration occurs in Alzheimer's disease (AD) is unclear but apoptosis is a conjectured trigger in multiple studies. Moreover, studies with post-mortem brains of AD patients showed increased levels of early growth response-1 (Egr-1), particularly in regions primarily manifested with AD pathology, such as hippocampus and frontal cortex. However, its pathological significance is unknown. Egr-1 is a critical transcription factor involved in various biological processes which include apoptosis, cell proliferation and cell survival. Depending on cellular context and al

APA, Harvard, Vancouver, ISO, and other styles

24

Leitch, Andrew Edward. "Cyclin-dependent kinase inhibitor drugs drive neutrophil granulocyte apoptosis by transcriptional inhibition of the key survival protein MCL-1." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/5922.

Full text

Abstract:

The normal physiological response to bacterial infection or wounding with threat of infection, termed inflammation, has been shown to be dysregulated in certain human diseases including (but not limited to): idiopathic pulmonary fibrosis, acute lung injury, arthritis and glomerulonephritis. The earliest arriving and most abundant cell responding to an inflammatory stimulus is the neutrophil granulocyte. It has been shown that under inflammatory conditions neutrophil granulocytes have extended longevity, enhanced responsiveness and upregulated activation parameters. In the setting of non-infect

APA, Harvard, Vancouver, ISO, and other styles

25

Debord, Jean. "Relation structure chimique-activité biologique pour quelques phosphoramides et benzamides." Poitiers, 1988. http://www.theses.fr/1988POIT2331.

Full text

Abstract:

Les constantes d'inhibition reversible de la butylcholinesterase par une serie de 16 phosphoramides aliphatiques ont ete determinees par spectrophotometrie et par microcalorimetrie. L'activite des substituants amines augmente avec la lipophilie. L'inhibition irreversible de la butylcholinesterase par le thio-tepa et le methyl-parathion a ete etudiee en suivant l'hydrolyse d'une faible concentration de substrat en presence de l'inhibiteur

APA, Harvard, Vancouver, ISO, and other styles

26

Subramanian, Gayatri. "TDRD7, a Novel Viral Restriction Factor, Inhibits Cellular AMP-dependent Kinase to Inhibit Virus Replication." University of Toledo Health Science Campus / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=mco1596574176173965.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

Pardali, Katerina. "Mechanisms of Regulation of the Cell Cycle Inhibitor p21^Waf1/Cip1 in TGF-β-Mediated Cell Growth Inhibition". Doctoral thesis, Uppsala University, Ludwig Institute for Cancer Research, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5892.

Full text

Abstract:

<p>TGF-β is the founding member of a multifunctional family of cytokines that regulate many aspects of cell physiology, including cell growth, differentiation, motility and death and play important roles in many developmental and pathological processes. TGF-β signals by binding to a heterotetrameric complex of type I and type II serine/threonine kinase receptors. The type I receptor is phosphorylated and activated by the type II receptor and propagates the signal to the nucleus by phosphorylating and activating receptor-regulated Smad proteins (R-Smads). Once activated, the R-Smads translocate

APA, Harvard, Vancouver, ISO, and other styles

28

CRACCHIOLO, SALVATORE. "Is suramin truly a good inhibitor of the bacterial RecA protein? Inhibition and activation, two sides of the same coin." Doctoral thesis, Università degli Studi dell'Aquila, 2021. http://hdl.handle.net/11697/169597.

Full text

Abstract:

Bacteria live in a hostile habitat and are continuously exposed to a multitude of environmental stress that can compromise the survival of the cells in the absence of an efficient adaptation system. To survive and adapt to these “hard” conditions, bacteria have developed a global response system that modulates the expression of specific genes and, consequently, the cellular metabolism, allowing the microorganisms to respond to the modification of the environment. This inducible system is termed SOS response, which is mainly triggered by lesion to DNA. The SOS response entails the induction of

APA, Harvard, Vancouver, ISO, and other styles

29

Wolf, Nicola M. [Verfasser], Bertold [Akademischer Betreuer] Hock, Bruce D. [Akademischer Betreuer] Hammock, and Siegfried [Akademischer Betreuer] Scherer. "Inhibition studies of soluble epoxide hydrolase : Development of two novel fluorescence-based inhibitor assay systems and cellular inhibition by RNAi / Nicola M. Wolf. Gutachter: Siegfried Scherer. Betreuer: Bertold Hock ; Bruce D. Hammock." München : Universitätsbibliothek der TU München, 2006. http://d-nb.info/1058141368/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

Martins, Nádia Helena. "Ensaios enzimáticos de proteases de HIV-1 de subtipos brasileiros." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/76/76132/tde-27042008-122417/.

Full text

Abstract:

Mesmo com o grande número de estudos relacionados à proteases do subtipo B e de como suas mutações podem interferir na estrutura, na resistência a inibidores e na eficiência catalítica da enzima, existe ainda uma lacuna de como as mudanças polimórficas de proteases de HIV de outros subtipos de HIV-1 interferem nesses fatores. Nesse contexto insere-se esse trabalho, que utilizou proteases de HIV-1 isoladas de pacientes brasileiros HIV-1 infectados com o subtipo F, e outros dois mutantes, sendo que um do subtipo F e outro do subtipo B para ensaios frente a seis inibidores comercialmente disponív

APA, Harvard, Vancouver, ISO, and other styles

31

Lembo, Gaia. "Substrate targeting and inhibition of editing deaminases." Doctoral thesis, Università di Siena, 2021. http://hdl.handle.net/11365/1144295.

Full text

Abstract:

Identification of small molecules against APOBEC3B The APOBECs are deaminases that act on DNA and RNA to restrict exogenous nucleic acids. Yet, the signature of their mutagenic activity –especially that of APOBEC3A and APOBEC3B- has been observed in the cancer genomes and their ability to increase the genetic heterogeneity of tumours has been linked to the onset of drug resistance in cancer. As such inhibition of their enzymatic activity represents a potential target for anticancer therapies. During my PhD I worked at the identification of APOBEC3B small-molecule inhibitors. To this aim, I us

APA, Harvard, Vancouver, ISO, and other styles

32

Huynh, Ngoc Huu. "The Inhibition Of Copper Corrosion In Aqueous Environments With Heterocyclic Compounds." Thesis, Queensland University of Technology, 2004. https://eprints.qut.edu.au/15951/1/Ngoc_Huu_Huynh_Thesis.pdf.

Full text

Abstract:

Benzotriazole (BTAH) has been used as a corrosion inhibitor for copper and copper-, based alloys for more than 40 years. It has been successfully employed for the, prevention of both atmospheric corrosion and particularly for the protection of, copper under immersed conditions. Whilst BTAH is an excellent inhibitor in alkaline, solution its efficiency drops off markedly as the pH decreases. It was hypothesized, that a possible way to increase surface adsorption and subsequent better inhibition, over a wide pH range might be through the preparation of derivatives, particularly, carboxybenzotria

APA, Harvard, Vancouver, ISO, and other styles

33

Huynh, Ngoc Huu. "The Inhibition Of Copper Corrosion In Aqueous Environments With Heterocyclic Compounds." Queensland University of Technology, 2004. http://eprints.qut.edu.au/15951/.

Full text

Abstract:

Benzotriazole (BTAH) has been used as a corrosion inhibitor for copper and copper-, based alloys for more than 40 years. It has been successfully employed for the, prevention of both atmospheric corrosion and particularly for the protection of, copper under immersed conditions. Whilst BTAH is an excellent inhibitor in alkaline, solution its efficiency drops off markedly as the pH decreases. It was hypothesized, that a possible way to increase surface adsorption and subsequent better inhibition, over a wide pH range might be through the preparation of derivatives, particularly, carboxybenzotria

APA, Harvard, Vancouver, ISO, and other styles

34

Glossop, Paul. "Thrombin inhibition." Thesis, University of Oxford, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.244533.

Full text

APA, Harvard, Vancouver, ISO, and other styles

35

Bonardi, C. "Discriminative inhibition." Thesis, University of Cambridge, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.384313.

Full text

APA, Harvard, Vancouver, ISO, and other styles

36

Chase, Alexander J. "Inhibition of transcription factor NF-#kappa#B : a potential strategy to inhibit metalloproteinase secretion by atherosclerosis plaque-resident cells." Thesis, University of Bristol, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.288559.

Full text

APA, Harvard, Vancouver, ISO, and other styles

37

Brian, Jessica Ann. "Inhibition in autism evidence of excessive inhibition-of-return /." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp02/NQ56219.pdf.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

Heduy, Fabrice. "Inhibition cognitive et schizophrénie : étude en situation d'auto-inhibition." Lille 3, 2001. http://www.theses.fr/2001LIL30010.

Full text

Abstract:

L'inhibition cognitive est généralement représentée comme un processus qui limite et contrôle l'accès des informations à la conscience. Sa défaillance participerait à la genèse des hallucinations et des délires et pourrait sous-tendre un grand nombre de troubles observés dans la schizophrénie. Par ailleurs, deux processus différents sont proposés pour rendre compte de l'inhibition. Le premier, étudié principalement grâce au paradigme d'amorçage négatif, est appelé inhibition latérale. Son étude a montré qu'il était souvent déficient chez les patients schizophrènes. En revanche, le second proce

APA, Harvard, Vancouver, ISO, and other styles

39

Geng, Xinyan. "Investigations into how best to target FGFR2 mutant endometrial cancer." Thesis, Queensland University of Technology, 2017. https://eprints.qut.edu.au/123437/1/Xinyan%20Geng%20Thesis.pdf.

Full text

Abstract:

Endometrial cancer (EC) is the fourth most common cancer in women in developed countries, such as North America, Europe and Australia. Patients with low-grade, early-stage disease usually have a favourable survival rate. However, patients that present at an advanced stage of disease have an average survival of only 12 months. Current treatments for these patients are radiation and chemotherapy, which offer limited clinical benefit. There is no efficient treatment for advanced EC. Improved therapeutic approaches are needed for the treatment of recurrent and metastatic endometrial cancer. Recent

APA, Harvard, Vancouver, ISO, and other styles

40

Fowell, Andrew. "The investigation of strategies to inhibit liver fibrosis by targeting tissue inhibitor of metalloproteinases with RNA interference." Thesis, University of Southampton, 2010. https://eprints.soton.ac.uk/362765/.

Full text

Abstract:

Current evidence suggests that tissue inhibitor of metalloproteinase (TIMP)-l and -2 are expressed by hepatic stellate cells (HSC during the course of their activation to a profibrotic myofibroblastic phenotype and play an important role in liver fibrogenesis. Therefore, inhibition of these key molecules represents an attractive strategy for treatment of liver fibrosis. RNA interference (RNAi) is a naturally occurring cellular mechanism involving sequence-dependent silencing of target gene expression througn degradation of messenger RNA {m RNA). Evidence has rapidly emerged that components of

APA, Harvard, Vancouver, ISO, and other styles

41

Pagnussatt, Fernanda Arnhold. "Inibidores enzimáticos de cereais e seu potencial de atividade antifúngica." reponame:Repositório Institucional da FURG, 2010. http://repositorio.furg.br/handle/1/2959.

Full text

Abstract:

Dissertação(mestrado) - Universidade Federal do Rio Grande, Programa de Pós-Graduação em Engenharia e Ciência de Alimentos, Escola de Química e Alimentos, 2010.<br>Submitted by Caroline Silva (krol_bilhar@hotmail.com) on 2012-08-19T20:54:12Z No. of bitstreams: 1 dissertao -fernanda pagnussatt.pdf: 1418590 bytes, checksum: 8967b30d06e7a8e26859db843f84ec54 (MD5)<br>Approved for entry into archive by Bruna Vieira(bruninha_vieira@ibest.com.br) on 2012-12-06T18:47:43Z (GMT) No. of bitstreams: 1 dissertao -fernanda pagnussatt.pdf: 1418590 bytes, checksum: 8967b30d06e7a8e26859db843f84ec54 (MD5)<br>Ma

APA, Harvard, Vancouver, ISO, and other styles

42

Bowditch, William Antony. "Response inhibition and associative learning : training stimulus specific response inhibition." Thesis, University of Exeter, 2016. http://hdl.handle.net/10871/24923.

Full text

Abstract:

Response inhibition, which refers to the ability to cancel an already initiated motor response, is often considered to be a hallmark of Executive Control. The popular view conceptualises these control processes as deliberate and top-down. How- ever, what if you have cancelled the same response (say stopping at a pedestrian crossing) to a given stimulus (in this example the red do not cross pictogram) many times before? Does the resulting action cancellation remain an exclusively top down act of control, or does it become bottom-up with practise. Research suggests that repeatedly pairing a stim

APA, Harvard, Vancouver, ISO, and other styles

43

Chowdhury, Nahian Shahmat. "Intracortical Inhibition and Response Inhibition in healthy adults and gamblers." Thesis, The University of Sydney, 2019. https://hdl.handle.net/2123/21945.

Full text

Abstract:

This thesis investigated whether the strength of primary motor cortex (M1) short-interval Intracortical inhibition (SICI) can predict an individual’s ability to stop prepotent actions. Experiments involved measuring SICI at rest (i.e. during relaxed muscle activity) or during a stop signal task. Chapter 3 showed that stronger resting-state SICI predicted more efficient stopping. Chapter 4 showed that more efficient stopping was associated with stronger SICI during action stopping. Chapter 5 showed that SICI in left and right M1 uniquely predicted stopping ability of the contralateral hand but

APA, Harvard, Vancouver, ISO, and other styles

44

Lejmi, Mrad Rim. "Genetic and Pharmacologic Inhibition of Cellular Inhibitor of Apoptosis 1 (cIAP1) Protein Expression Protects Against Denervation-Induced Skeletal Muscle Atrophy In Vivo." Thesis, Université d'Ottawa / University of Ottawa, 2016. http://hdl.handle.net/10393/34260.

Full text

Abstract:

Skeletal muscle atrophy is a debilitating condition caused by pathological conditions including cancer cachexia, disuse and denervation. Disuse atrophy is characterized by reduction in fiber size, fiber-type change and induction of markers of atrophy such as MuRF1 and Fn14. Recent studies have focused on understanding the fundamental role of signalling pathways and the proteolytic system in response to muscle atrophy. Unfortunately the exact mechanisms behind atrophy remain poorly understood. I recently demonstrated that cIAP1 and/or cIAP2 proteins are critical regulators of NF-kB activation,

APA, Harvard, Vancouver, ISO, and other styles

45

Frings, Christian. "Inhibition von Distraktorinformation." Kassel : Kassel Univ. Press, 2004. http://deposit.d-nb.de/cgi-bin/dokserv?idn=97180110X.

Full text

APA, Harvard, Vancouver, ISO, and other styles

46

Smith, Gary Thomas. "Inhibition of IPNS." Thesis, University of Oxford, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.276831.

Full text

APA, Harvard, Vancouver, ISO, and other styles

47

Satou, Yorifumi. "Proteasome inhibitor, bortezomib, potently inhibits the growth of adult T-cell leukemia cells both in vivo and in vitro." Kyoto University, 2005. http://hdl.handle.net/2433/144734.

Full text

APA, Harvard, Vancouver, ISO, and other styles

48

Painter, Palak Rajeshkumar. "Quantitative analysis of glycinergic neurons including Ia inhibitory interneurons in the ventral spinal cord using a BAC-GlyT2-eGFP transgenic mouse model." Wright State University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=wright1347911464.

Full text

APA, Harvard, Vancouver, ISO, and other styles

49

Martínez, Høyer Sergio 1983. "Unraveling the molecular mechanisms involved in RCAN-peptide mediated inhibition of calcineurin-NFAT signaling and its potential as an inhibitor of tumor progressions." Doctoral thesis, Universitat Pompeu Fabra, 2012. http://hdl.handle.net/10803/123913.

Full text

Abstract:

The calcineurin-NFATc signaling pathway is involved in many aspects of the development and function of the immune, neural, skeletal, cardiovascular and muscular system of vertebrates. Regulators of Calcineurin (RCAN) proteins constitute a family of endogenous regulators of calcineurin, which play an important role in the modulation of the calcineurin-NFATc pathway. Here, we identifiy a novel protein kinase CK2 dependent mechanism by which the CIC motif of RCAN proteins modulate the final signaling output of the pathway. Moreover, we show that the functional CIC motif of RCANs responsib

APA, Harvard, Vancouver, ISO, and other styles

50

Nagao, Rina. "Growth inhibition of imatinib-resistant CML cells with the T315I mutation and hypoxia-adaptation by AV65 - a novel Wnt/β-catenin signaling inhibitor". Kyoto University, 2012. http://hdl.handle.net/2433/157488.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!