Academic literature on the topic 'Integrative Conjugative Elements (ICEs)'

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Journal articles on the topic "Integrative Conjugative Elements (ICEs)"

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Bellanger, Xavier, Adam P. Roberts, Catherine Morel, et al. "Conjugative Transfer of the Integrative Conjugative Elements ICESt1 and ICESt3 from Streptococcus thermophilus." Journal of Bacteriology 191, no. 8 (2009): 2764–75. http://dx.doi.org/10.1128/jb.01412-08.

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ABSTRACT Integrative and conjugative elements (ICEs), also called conjugative transposons, are genomic islands that excise, self-transfer by conjugation, and integrate in the genome of the recipient bacterium. The current investigation shows the intraspecies conjugative transfer of the first described ICEs in Streptococcus thermophilus, ICESt1 and ICESt3. Mitomycin C, a DNA-damaging agent, derepresses ICESt3 conjugative transfer almost 25-fold. The ICESt3 host range was determined using various members of the Firmicutes as recipients. Whereas numerous ICESt3 transconjugants of Streptococcus py
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Zakharova, I. B., and D. V. Viktorov. "Integrative conjugative elements (ICEs) of microorganisms." Molecular Genetics, Microbiology and Virology 30, no. 3 (2015): 114–23. http://dx.doi.org/10.3103/s0891416815030076.

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Iannelli, Francesco, Francesco Santoro, Marco R. Oggioni, and Gianni Pozzi. "Nucleotide Sequence Analysis of Integrative Conjugative Element Tn5253of Streptococcus pneumoniae." Antimicrobial Agents and Chemotherapy 58, no. 2 (2013): 1235–39. http://dx.doi.org/10.1128/aac.01764-13.

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ABSTRACTConjugative transposon Tn5253, an integrative conjugative element (ICE) ofStreptococcus pneumoniaecarrying thecatandtet(M) genes, was shown to be 64,528 bp in size and to contain 79 open reading frames, of which only 38 could be annotated. Two distinct genetic elements were found integrated into Tn5253: Tn5251(18,033 bp), of the Tn916-Tn1545family of ICEs, and Ωcat(pC194) (7,627 bp), which could not conjugate but was capable of intracellular mobility by excision, circularization, and integration by homologous recombination. The highest conjugation frequency of Tn5253was observed whenSt
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Bioteau, Audrey, Romain Durand, and Vincent Burrus. "Redefinition and Unification of the SXT/R391 Family of Integrative and Conjugative Elements." Applied and Environmental Microbiology 84, no. 13 (2018): e00485-18. http://dx.doi.org/10.1128/aem.00485-18.

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ABSTRACT Integrative and conjugative elements (ICEs) of the SXT/R391 family are key drivers of the spread of antibiotic resistance in Vibrio cholerae, the infectious agent of cholera, and other pathogenic bacteria. The SXT/R391 family of ICEs was defined based on the conservation of a core set of 52 genes and site-specific integration into the 5′ end of the chromosomal gene prfC. Hence, the integrase gene int has been intensively used as a marker to detect SXT/R391 ICEs in clinical isolates. ICEs sharing most core genes but differing by their integration site and integrase gene have been recen
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Lei, Chang-Wei, An-Yun Zhang, Hong-Ning Wang, Bi-Hui Liu, Li-Qin Yang, and Yong-Qiang Yang. "Characterization of SXT/R391 Integrative and Conjugative Elements in Proteus mirabilis Isolates from Food-Producing Animals in China." Antimicrobial Agents and Chemotherapy 60, no. 3 (2016): 1935–38. http://dx.doi.org/10.1128/aac.02852-15.

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SXT/R391 integrative and conjugative elements (ICEs) were detected in 8 out of 125Proteus mirabilisisolates from food-producing animals in China. Whole-genome sequencing revealed that seven ICEs were identical to ICEPmiJpn1, carrying the cephalosporinase geneblaCMY-2. Another one, designated ICEPmiChn1, carried five resistance genes. All eight ICEs could be transferred toEscherichia colivia conjugation. The results highlight the idea that animal farms are important reservoir of the SXT/R391 ICE-containingP. mirabilis.
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Libante, Virginie, Yves Nombre, Charles Coluzzi, et al. "Chromosomal Conjugative and Mobilizable Elements in Streptococcus suis: Major Actors in the Spreading of Antimicrobial Resistance and Bacteriocin Synthesis Genes." Pathogens 9, no. 1 (2019): 22. http://dx.doi.org/10.3390/pathogens9010022.

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Streptococcus suis is a zoonotic pathogen suspected to be a reservoir of antimicrobial resistance (AMR) genes. The genomes of 214 strains of 27 serotypes were screened for AMR genes and chromosomal Mobile Genetic Elements (MGEs), in particular Integrative Conjugative Elements (ICEs) and Integrative Mobilizable Elements (IMEs). The functionality of two ICEs that host IMEs carrying AMR genes was investigated by excision tests and conjugation experiments. In silico search revealed 416 ICE-related and 457 IME-related elements. These MGEs exhibit an impressive diversity and plasticity with tandem a
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Haskett, Timothy L., Jason J. Terpolilli, Amanuel Bekuma, et al. "Assembly and transfer of tripartite integrative and conjugative genetic elements." Proceedings of the National Academy of Sciences 113, no. 43 (2016): 12268–73. http://dx.doi.org/10.1073/pnas.1613358113.

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Integrative and conjugative elements (ICEs) are ubiquitous mobile genetic elements present as “genomic islands” within bacterial chromosomes. Symbiosis islands are ICEs that convert nonsymbiotic mesorhizobia into symbionts of legumes. Here we report the discovery of symbiosis ICEs that exist as three separate chromosomal regions when integrated in their hosts, but through recombination assemble as a single circular ICE for conjugative transfer. Whole-genome comparisons revealed exconjugants derived from nonsymbiotic mesorhizobia received three separate chromosomal regions from the donorMesorhi
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Hirose, Jun. "Diversity and Evolution of Integrative and Conjugative Elements Involved in Bacterial Aromatic Compound Degradation and Their Utility in Environmental Remediation." Microorganisms 11, no. 2 (2023): 438. http://dx.doi.org/10.3390/microorganisms11020438.

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Integrative and conjugative elements (ICEs) are mobile DNA molecules that can be transferred through excision, conjugation, and integration into chromosomes. They contribute to the horizontal transfer of genomic islands across bacterial species. ICEs carrying genes encoding aromatic compound degradation pathways are of interest because of their contribution to environmental remediation. Recent advances in DNA sequencing technology have increased the number of newly discovered ICEs in bacterial genomes and have enabled comparative analysis of their evolution. The two different families of ICEs
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Iannelli, Francesco, Francesco Santoro, Valeria Fox, and Gianni Pozzi. "A Mating Procedure for Genetic Transfer of Integrative and Conjugative Elements (ICEs) of Streptococci and Enterococci." Methods and Protocols 4, no. 3 (2021): 59. http://dx.doi.org/10.3390/mps4030059.

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DNA sequencing of whole bacterial genomes has revealed that the entire set of mobile genes (mobilome) represents as much as 25% of the bacterial genome. Despite the huge availability of sequence data, the functional analysis of the mobile genetic elements (MGEs) is rarely reported. Therefore, established laboratory protocols are needed to investigate the biology of this important part of the bacterial genome. Conjugation is a mechanism of horizontal gene transfer which allows the exchange of MGEs among strains of the same or different bacterial species. In streptococci and enterococci, integra
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Dimopoulou, Ioanna D., Sofia I. Kartali, Rosalind M. Harding, Tim E. A. Peto, and Derrick W. Crook. "Diversity of antibiotic resistance integrative and conjugative elements among haemophili." Journal of Medical Microbiology 56, no. 6 (2007): 838–46. http://dx.doi.org/10.1099/jmm.0.47125-0.

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The objective of this study was to investigate the sequence diversity in a single country of a family of integrative and conjugative elements (ICEs) that are vectors of antibiotic resistance in Haemophilus influenzae and Haemophilus parainfluenzae, and test the hypothesis that they emerged from a single lineage. Sixty subjects aged 9 months – 13 years were recruited and oropharyngeal samples cultured. Up to 10 morphologically distinct Pasteurellaceae spp. were purified, and then the species were determined and differentiated by partial sequence analysis of 16S rDNA and mdh, respectively. ICEs
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Dissertations / Theses on the topic "Integrative Conjugative Elements (ICEs)"

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Lao, Julie. "Conception et mise en oeuvre d’une approche bioinformatique dédiée à l’identification des ICE, IME et éléments composites dans les génomes de Firmicutes." Electronic Thesis or Diss., Université de Lorraine, 2021. http://www.theses.fr/2021LORR0063.

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Les ICE (Éléments intégratifs conjugatifs) et les IME (Éléments intégratifs mobilisables) sont des éléments mobiles bactériens qui jouent un rôle clé dans les transferts horizontaux. Ils ont la capacité de s'intégrer et de se transférer par conjugaison d'une bactérie à une autre. Ces éléments sont très répandus dans les génomes bactériens mais sont encore mal connus. Leur identification automatique est un défi et ils ne sont en général pas annotés dans les génomes. Jusqu'à présent, seules deux approches bioinformatiques permettent la détection des ICE et la détection des IME, mais leur fiabili
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Coluzzi, Charles. "L'exploration des génomes par l'outil ICEFinder révèle la forte prévalence et l'extrême diversité des ICE et des IME de streptocoques." Thesis, Université de Lorraine, 2017. http://www.theses.fr/2017LORR0352/document.

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Les éléments génétiques mobiles contribuent grandement à la diversité et à l’évolution des génomes bactériens par le biais du transfert horizontal. Parmi eux, les éléments intégratifs conjugatifs (ICE) codent leur propre excision, leur transfert par conjugaison et leur intégration. En revanche, les éléments intégratifs et mobilisables (IME) ne sont autonomes que pour leur excision et intégration et ne codent seulement que certaines des protéines/fonctions (oriT) dont ils ont besoin pour leur transfert conjugatif. Par conséquent, les IME ont besoin d’un élément conjugatif « helper » pour se tra
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Wright, Laurel D. "Autonomous replication of integrative and conjugative elements." Thesis, Massachusetts Institute of Technology, 2016. http://hdl.handle.net/1721.1/106738.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, 2016.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references.<br>Mobile genetic elements facilitate movement of genes, including those conferring antibiotic resistance and other traits, between bacteria. Integrative and conjugative elements (ICEs), also known as conjugative transposons, are a large family of mobile genetic elements that can transfer between neighboring cells. ICEs are found integrated in the chromosome of their host bacterium, where they are transmitted to daughter cells by c
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Nouvel, Laurent-Xavier. "Etude de la diversité génétique de Mycoplasma agalactiae : plasticité des génomes, mobilome et dynamique de surface." Thesis, Toulouse, INPT, 2009. http://www.theses.fr/2009INPT013A/document.

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Mycoplasma agalactiae est responsable de l'agalactie contagieuse, maladie des petits ruminants difficilement contrôlée et figurant sur la liste de l’OIE. Afin d’évaluer la diversité génétique de ce pathogène, 101 isolats ont été comparés par trois techniques (VNTR, RFLP, répertoire vpma). Les résultats révèlent une grande homogénéité génétique dont la souche type PG2 est représentative. Quelques isolats font exception telle la souche 5632 que nous avons séquencée et analysée ici. La comparaison des génomes et des protéomes entre 5632 et PG2 indiquent que la plasticité de ces génomes est liée à
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Haskett, Timothy L. "Discovery and characterisation of tripartite Integrative & Conjugative Elements." Thesis, Haskett, Timothy L. (2018) Discovery and characterisation of tripartite Integrative & Conjugative Elements. PhD thesis, Murdoch University, 2018. https://researchrepository.murdoch.edu.au/id/eprint/41086/.

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Bacterial integrative & conjugative elements (ICEs) are chromosomally-integrated DNA islands that excise to form circular molecules capable of horizontal self-transmission via conjugation (cell-to-cell contact). Symbiosis ICEs, such as ICEMlSymR7A of Mesorhizobium loti, are a group of ICEs that carry genes enabling rhizobial bacteria to engage in N2-fixing symbioses with leguminous plants. Transfer of symbiosis ICEs can convert non-symbiotic rhizobia into legume symbionts in a single evolutionary step. In this thesis, a novel form of “tripartite” ICE (ICE3) is reported that exists as three
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Stagg, Georgina. "Creation and characterisation of genetically-marked Mesorhizobium integrative and conjugative elements." Thesis, Stagg, Georgina (2018) Creation and characterisation of genetically-marked Mesorhizobium integrative and conjugative elements. Honours thesis, Murdoch University, 2018. https://researchrepository.murdoch.edu.au/id/eprint/42888/.

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Rhizobia are soil-dwelling bacteria capable of forming symbiotic associations with legumes, where they reduce atmospheric dinitrogen (N2) into ammonia (NH3), providing the host plant with a bioavailable nitrogen source. For rhizobia in the genus Mesorhizobium, genes essential to the establishment (nod) and maintenance of nitrogen fixing-legume symbioses (nif and fix) are chromosomally-encoded on mobile segments of DNA known as symbiosis integrative and conjugative elements (ICEs). Symbiosis ICEs are capable of excising from the host chromosome and transferring to a recipient ICE-free cell via
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Farzand, Robeena. "Occurrence and roles of two integrative and conjugative elements in Klebsiella pneumoniae." Thesis, University of Leicester, 2017. http://hdl.handle.net/2381/40665.

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The genome of Klebsiella pneumoniae HS11286 carries two integrative and conjugative elements (ICEs), ICEKpnHS-1 and ICEKpnHS-2; the former belongs to the ICEKp1 family and the latter was unexplored. This study was designed to further characterise the two ICEs, and investigate their prevalence in local clinical K. pneumoniae isolates. Sequence analysis showed that ICEKpnHS-2 belonged to the subfamily of PAPI elements with XerC-like integrases and PCR screening revealed that ICEKpnHS-1 associated elements were more (30%) prevalent in local isolates compared to ICEKpnHS-2 (12.5%). Contributions o
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fox, Valeria. "Mobile genetic elements carrying stress response systems, antibiotic resistance determinants, and catabolic pathways." Doctoral thesis, Università di Siena, 2021. http://hdl.handle.net/11365/1159250.

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In the present thesis, I studied the activation of an SOS-like response in Streptococcus pneumoniae encoded by the Streptococcus pyogenes prophage φ1207.3. This system leads to the temporary activation of an hypermutable phenotype, which resulted in increased survival and increased mutation rate upon exposure to mitomycin C or UV-C light. Then, a different type of stress response, the Envelope Stress Response (ESR), was exploited as a strategy for sensitization of Escherichia coli to several antibiotics, by disbalancing five pathways, namely σE, Cpx, Rcs, Bae, and Psp. Disbalancing the Psp pat
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Laroussi, Haifa. "Étude des mécanismes moléculaires d'initiation du transfert conjugatif d'ICESt3, médiée par une relaxase MOBT chez la bactérie Gram+ Streptococcus thermophilus." Electronic Thesis or Diss., Université de Lorraine, 2022. http://www.theses.fr/2022LORR0176.

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Les génomes bactériens évoluent principalement grâce au transfert horizontal de gènes. La conjugaison bactérienne en est un des mécanismes majeurs. Elle est notamment médiée par les éléments intégratifs et conjugatifs (ICE). En plus de leur transfert, les ICE codent d'autres fonctions conférant à leur hôte un avantage adaptatif, comme par exemple des résistances aux antibiotiques dont la diffusion est un enjeu majeur en santé publique. Il est donc nécessaire de comprendre comment les ICE se transfèrent si l'on veut limiter leur dissémination. Le transfert d'un ICE d'une cellule donatrice vers
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SPAGNOLETTI, MATTEO. "Comparative genomics of V. cholerae 7th pandemic strains. Analysis of integrative conjugative elements, genomic islands and prophages." Doctoral thesis, 2012. http://hdl.handle.net/11573/917386.

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Book chapters on the topic "Integrative Conjugative Elements (ICEs)"

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Cury, Jean, Sophie S. Abby, Olivia Doppelt-Azeroual, Bertrand Néron, and Eduardo P. C. Rocha. "Identifying Conjugative Plasmids and Integrative Conjugative Elements with CONJscan." In Horizontal Gene Transfer. Springer US, 2019. http://dx.doi.org/10.1007/978-1-4939-9877-7_19.

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Cunha, Violette Da, Romain Guérillot, Mathieu Brochet, and Philippe Glaser. "Integrative and Conjugative Elements Encoding DDE Transposases." In Bacterial Integrative Mobile Genetic Elements. CRC Press, 2022. http://dx.doi.org/10.1201/9780367813925-15.

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Ciric, Lena, Azmiza Jasni, Lisbeth Elvira de Vries, Yvonne Agersø, Peter Mullany, and Adam P. Roberts. "The Tn916/Tn1545 Family of Conjugative Transposons." In Bacterial Integrative Mobile Genetic Elements. CRC Press, 2022. http://dx.doi.org/10.1201/9780367813925-9.

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Garriss, Geneviéve, and Vincent Burrus. "Integrating Conjugative Elements of the SXT/R391 Family." In Bacterial Integrative Mobile Genetic Elements. CRC Press, 2022. http://dx.doi.org/10.1201/9780367813925-13.

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Salyers, Abigail A., Jeffrey F. Gardner, and Nadja B. Shoemaker. "Excision and Transfer of Bacteroides Conjugative Integrated Elements." In Bacterial Integrative Mobile Genetic Elements. CRC Press, 2022. http://dx.doi.org/10.1201/9780367813925-14.

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Berkmen, Melanie B., Stephanie J. Laurer, Bridget K. Giarusso, and Rodrigo Romero. "The Integrative and Conjugative Element ICEBs1 of Bacillus subtilis." In Bacterial Integrative Mobile Genetic Elements. CRC Press, 2022. http://dx.doi.org/10.1201/9780367813925-12.

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Esnault, Emilie, Alain Raynal, and Jean-Luc Pernodet. "pSAM2, a Paradigm for a Family of Actinomycete Integrative and Conjugative Elements." In Bacterial Integrative Mobile Genetic Elements. CRC Press, 2022. http://dx.doi.org/10.1201/9780367813925-8.

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A., Minimol V., Pankaj Kishore, and Mukteswar Prasad Mothadaka. "Evolution and the Role of SXT-Related Integrative Conjugative Elements in Multidrug-Resistant Vibrio cholerae." In Handbook on Antimicrobial Resistance. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-16-9723-4_22-1.

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Minimol, V. A., Pankaj Kishore, and Mukteswar Prasad Mothadaka. "Evolution and the Role of SXT-Related Integrative Conjugative Elements in Multidrug-Resistant Vibrio cholerae." In Handbook on Antimicrobial Resistance. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-19-9279-7_22.

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Armshaw, Patricia, and J. Tony Pembroke. "UV Stress-Responsive Genes Associated with Enterobacterial Integrative Conjugative Elements of the ICE SXT/R391 Group." In Stress and Environmental Regulation of Gene Expression and Adaptation in Bacteria. John Wiley & Sons, Inc., 2016. http://dx.doi.org/10.1002/9781119004813.ch48.

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