Academic literature on the topic 'Intracellular signals'

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Journal articles on the topic "Intracellular signals"

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Imboden, J. B., and G. A. Koretsky. "Intracellular Signalling: Switching off signals." Current Biology 5, no. 7 (July 1995): 727–29. http://dx.doi.org/10.1016/s0960-9822(95)00145-x.

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Kalaidzidis, Yannis, Hernán Morales-Navarrete, Inna Kalaidzidis, and Marino Zerial. "Intracellular Background Estimation for Quantitative Fluorescence Microscopy." Proceedings 33, no. 1 (December 6, 2019): 22. http://dx.doi.org/10.3390/proceedings2019033022.

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Fluorescently targeted proteins are widely used for studies of intracellular organelles dynamic. Peripheral proteins are transiently associated with organelles and a significant fraction of them are located at the cytosol. Image analysis of peripheral proteins poses a problem on properly discriminating membrane-associated signal from the cytosolic one. In most cases, signals from organelles are compact in comparison with diffuse signal from cytosol. Commonly used methods for background estimation depend on the assumption that background and foreground signals are separable by spatial frequency
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IKATAYAMA, Yoshiki. "Polymer Drugs Responding to Intracellular Signals." Kobunshi 55, no. 5 (2006): 326–29. http://dx.doi.org/10.1295/kobunshi.55.326.

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Song, Jianxun, Fengyang Tylan Lei, Xiaofang Xiong, and Rizwanul Haque. "Intracellular Signals of T Cell Costimulation." Cellular & Molecular Immunology 5, no. 4 (August 2008): 239–47. http://dx.doi.org/10.1038/cmi.2008.30.

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Cao, Y., A. T. Pearman, G. A. Zimmerman, T. M. McIntyre, and S. M. Prescott. "Intracellular unesterified arachidonic acid signals apoptosis." Proceedings of the National Academy of Sciences 97, no. 21 (September 26, 2000): 11280–85. http://dx.doi.org/10.1073/pnas.200367597.

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Konieczny, Vera, Michael V. Keebler, and Colin W. Taylor. "Spatial organization of intracellular Ca2+ signals." Seminars in Cell & Developmental Biology 23, no. 2 (April 2012): 172–80. http://dx.doi.org/10.1016/j.semcdb.2011.09.006.

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Rüdiger, Sten. "Stochastic models of intracellular calcium signals." Physics Reports 534, no. 2 (January 2014): 39–87. http://dx.doi.org/10.1016/j.physrep.2013.09.002.

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Seuwen, Klaus, and Jaques Pouysségur. "Intracellular signals in the mitogenic response." Fresenius' Zeitschrift für analytische Chemie 330, no. 4-5 (January 1988): 308–9. http://dx.doi.org/10.1007/bf00469223.

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Ramseyer, Lorenz T. H., Janet Barker-Harrel, David J. Smith, Kari A. McBride, Robert N. Jarman, and Robert H. Broyles. "Intracellular signals for developmental hemoglobin switching." Developmental Biology 133, no. 1 (May 1989): 262–71. http://dx.doi.org/10.1016/0012-1606(89)90317-5.

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Gruol, D. L., J. G. Netzeband, and K. L. Parsons. "Ca2+ signaling pathways linked to glutamate receptor activation in the somatic and dendritic regions of cultured cerebellar purkinje neurons." Journal of Neurophysiology 76, no. 5 (November 1, 1996): 3325–40. http://dx.doi.org/10.1152/jn.1996.76.5.3325.

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1. Ca2+ signaling elicited by ionotropic alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)/kainate (iGluR) and metabotropic (mGluR) glutamate receptor agonists was studied in the somatic and dendritic regions of cultured cerebellar Purkinje neurons using microscopic video imaging and the Ca2+ sensitive dye fura-2. 2. iGluR and mGluR agonists and K+ depolarization applied by brief micropressure pulses evoked Ca2+ signals in both the somatic and dendritic regions of all Purkinje neurons studied. The Ca2+ signals were generated simultaneously in both cellular regions. The Ca+ signal
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Dissertations / Theses on the topic "Intracellular signals"

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Nair, Prashant. "Signals involved in protein intracellular sorting /." Basel : [s.n.], 2005. http://edoc.unibas.ch/diss/DissB_6999.

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劉思恩 and See-yan Lau. "A study of intracellular signals of K-opioids in non-neuronal cells." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1997. http://hub.hku.hk/bib/B31214290.

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Lau, See-yan. "A study of intracellular signals of K-opioids in non-neuronal cells /." Hong Kong : University of Hong Kong, 1997. http://sunzi.lib.hku.hk/hkuto/record.jsp?B19667139.

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Liu, Ke, University of Western Sydney, of Science Technology and Environment College, and of Science Food and Horticulture School. "Role of second messengers in controlling growth patterns of corneal epithelial cells." THESIS_CSTE_SFH_Liu_K.xml, 2002. http://handle.uws.edu.au:8081/1959.7/387.

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The purpose of this thesis was to investigate mechanisms contolling the growth of corneal epithelial cells, particularly the intracellular signals involved with stratification compared with cellular migration and maturation. Buttons of epithelium were cultured in different culture media. The explants were monitored microscopically for their growth patterns and finally fixed and examined for cytokeratin, vimentin and actin. Different growth patterns were observed in the different media, indicating that different signalling patterns must be operating in these cells depending upon the media in wh
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Levings, Megan K. "Biological and biochemical analyses of the distinctive intracellular signals activated by interleukin-4." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape8/PQDD_0025/NQ38928.pdf.

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Raraty, Michael Gordon Thomas. "Cytosolic calcium signals and intracellular enzyme activation in the pathogenesis of acute pancreatitis." Thesis, University of Liverpool, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.250238.

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Bradley, J. "Analysis of the mechanisms responsible for the generation and decoding of intracellular calcium signals." Thesis, University of Cambridge, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.596849.

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In many cells, including hepatocytes, receptors coupled to phosphoinositide hydrolysis stimulate oscillatory changes in cytosolic [Ca<SUP>2+</SUP>] ([Ca<SUP>2+</SUP>]<SUB>i</SUB>). I have used two methods to examine the means whereby such [Ca<SUP>2+</SUP>]<SUB>i</SUB> transients are linked to the stimulation of glycogenolysis. By perifusing rat hepatocytes prelabelled with [<SUP>3</SUP>H]-glucose, I showed that phenylephrine increases the rate of [<SUP>3</SUP>H]-glucose release by 2-3 fold, and confirmed this effect using a colorimetric assay for glucose. When cultured hepatocytes were loaded
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Righetti, Karima Maria. "Study of Rsm/Gac post-transcriptional regulation by quorum sensing, extracellular and intracellular signals in Pseugomonas aeruginosa." Thesis, University of Nottingham, 2011. http://eprints.nottingham.ac.uk/13853/.

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Bacteria have evolved ways to sense and respond to changes in their population density through quorum sensing (QS) systems, and to adapt to changes in the extracellular environment through two component systems (TCS). In Pseudomonas aeruginosa, QS and the GacS/GacA TCS are global regulatory systems that modulate the expression of virulence genes at the transcriptional and post-transcriptional level, respectively. Although in P. aeruginosa the QS network has been extensively characterized, the way the Gac/Rsm global regulatory system is regulated is still unclear. The study of QS and Gac/Rsm ne
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Huang, Yun. "Integration of Extracellular and Intracellular Calcium Signals: Roles of Calcium-Sensing Receptor (CASR), Calmodulin and Stromal Interaction Molecule 1 (STIM1)." Atlanta, Ga. : Georgia State University, 2008. http://digitalarchive.gsu.edu/chemistry_diss/28/.

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Thesis (Ph. D.)--Georgia State University, 2008.<br>Title from title page (Digital Archive@GSU, viewed July 1, 2010) Jenny J. Yang, committee chair; Edward Brown, Giovanni Gadda, Zhi-ren Liu, committee members. Includes bibliographical references (p. 230-258).
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Lemaire, Mathieu. "Intracellular signals underlying the inductive effects of agrin during neuromuscular junction formation : study on the roles of ras and Shc." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0030/MQ64388.pdf.

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Books on the topic "Intracellular signals"

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1961-, Yang Zhenbiao, ed. Intracellular signaling in plants. Oxford: Wiley-Blackwell Pub., 2008.

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Wilks, Andrew F. Intracellular signal transduction: The JAK-STAT pathway. New York: Springer, 1996.

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Wilks, Andrew F., and Ailsa G. Harpur. Intracellular Signal Transduction: The JAK-STAT Pathway. Berlin, Heidelberg: Springer Berlin Heidelberg, 1996. http://dx.doi.org/10.1007/978-3-662-22050-4.

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Intracellular parasitism of microorganisms. New York: Springer, 1996.

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C, Mobley William, Christen Yves, and SpringerLink (Online service), eds. Intracellular Traffic and Neurodegenerative Disorders. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009.

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B, Hoek Jan, and National Institute on Alcohol Abuse and Alcoholism (U.S.), eds. Ethanol and intracellular signaling: From molecules to behavior. Bethesda, MD (6000 Executive Blvd., Bethesda 20892): U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, National Institute on Alcohol Abuse and Alcoholism, 2000.

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Hoek, Jan B. Ethanol and intracellular signaling: From molecules to behavior. Bethesda, MD (6000 Executive Boulevard, Bethesda, 20892): U.S. Department of Health and Human Services, Public Health Service, National Institute of Health, National Institute on Alcohol Abuse and Alcoholism, 2000.

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R, Nahorski S., ed. Transmembrane signalling, intracellular messengers, and implications for drug development. Chichester: Wiley, 1990.

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Jeroen, Pasterkamp R., ed. Semaphorins: Receptor and intracellular signaling mechanisms. New York, N.Y: Springer Science+Business Media, 2007.

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Karin, Müller-Decker, and Klingmüller Ursula, eds. Cellular signal processing. New York, NY: Garland Science, 2009.

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Book chapters on the topic "Intracellular signals"

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Atherton, Philip J., and Nathaniel J. Szewczyk. "Chapter 5. Regulation of Muscle Proteostasis via Extramuscular Signals." In Extracellular and Intracellular Signaling, 77–104. Cambridge: Royal Society of Chemistry, 2011. http://dx.doi.org/10.1039/9781849733434-00077.

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Salehi, Ahmad, Chengbiao Wu, Ke Zhan, and William C. Mobley. "Axonal Transport of Neurotrophic Signals: An Achilles' Heel for Neurodegeneration?" In Intracellular Traffic and Neurodegenerative Disorders, 87–101. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-87941-1_7.

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Denizot, Audrey, Hugues Berry, and Sharmila Venugopal. "Intracellular Calcium Signals in Astrocytes, Computational Modeling of." In Encyclopedia of Computational Neuroscience, 1–12. New York, NY: Springer New York, 2020. http://dx.doi.org/10.1007/978-1-4614-7320-6_100693-1.

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Hessels, Anne M., and Maarten Merkx. "Genetically Encoded Fluorescent Probes for Intracellular Zn2+ Imaging." In Zinc Signals in Cellular Functions and Disorders, 135–59. Tokyo: Springer Japan, 2014. http://dx.doi.org/10.1007/978-4-431-55114-0_7.

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Iino, Masamitsu. "Dynamic regulation of intracellular calcium signals through calcium release channels." In Muscle Physiology and Biochemistry, 185–90. Boston, MA: Springer US, 1999. http://dx.doi.org/10.1007/978-1-4615-5543-8_23.

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Schulz, I., H. Streb, and F. Thevenod. "Intracellular Signals in Stimulation of Enzyme Secretion from Exocrine Glands." In Calcium Electrogenesis and Neuronal Functioning, 166–75. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-70744-5_15.

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Negro-Vilar, A., M. M. Valenca, and M. D. Culler. "Transmembrane Signals and Intracellular Messengers Mediating LHRH and LH Secretion." In Advances in Experimental Medicine and Biology, 85–108. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-5395-9_5.

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Graff van Creveld, Shiri, Avia Mizrachi, and Assaf Vardi. "An Ocean of Signals: Intracellular and Extracellular Signaling in Diatoms." In The Molecular Life of Diatoms, 641–78. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-92499-7_22.

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Neagu, Monica, and Carolina Constantin. "Signal Transduction in Immune Cells and Protein Kinases." In Advances in Experimental Medicine and Biology, 133–49. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-49844-3_5.

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AbstractImmune response relies upon several intracellular signaling events. Among the protein kinases involved in these pathways, members of the protein kinase C (PKC) family are prominent molecules because they have the capacity to acutely and reversibly modulate effector protein functions, controlling both spatial distribution and dynamic properties of the signals. Different PKC isoforms are involved in distinct signaling pathways, with selective functions in a cell-specific manner.In innate system, Toll-like receptor signaling is the main molecular event triggering effector functions. Various isoforms of PKC can be common to different TLRs, while some of them are specific for a certain type of TLR. Protein kinases involvement in innate immune cells are presented within the chapter emphasizing their coordination in many aspects of immune cell function and, as important players in immune regulation.In adaptive immunity T-cell receptor and B-cell receptor signaling are the main intracellular pathways involved in seminal immune specific cellular events. Activation through TCR and BCR can have common intracellular pathways while others can be specific for the type of receptor involved or for the specific function triggered. Various PKC isoforms involvement in TCR and BCR Intracellular signaling will be presented as positive and negative regulators of the immune response events triggered in adaptive immunity.
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Li, Ming, and Songwei Wu. "Regulation of T-Type Ca2+ Channels by Intercellular and Intracellular Signals." In T-type Calcium Channels in Basic and Clinical Science, 19–35. Vienna: Springer Vienna, 2014. http://dx.doi.org/10.1007/978-3-7091-1413-1_2.

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Conference papers on the topic "Intracellular signals"

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Harootunian, A. T., J. P. Kao, and Roger Y. Tsien. "Fluorescence Ratio Imaging Of Dynamic Intracellular Signals." In 33rd Annual Techincal Symposium, edited by John E. Wampler. SPIE, 1989. http://dx.doi.org/10.1117/12.962706.

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Erickson, Geoffrey R., and Farshid Guilak. "Osmotic Stress Initiates Intracellular Calcium Waves in Chondrocytes Through Extracellular Influx and the Inositol Phosphate Pathway." In ASME 1999 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1999. http://dx.doi.org/10.1115/imece1999-0580.

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Abstract The biophysical environment of the chondrocytes plays an important role in the health, turnover, and homeostasis of articular cartilage. Under normal physiologic loading, chondrocytes are exposed to a complex and diverse array of biophysical signals, including mechanical and osmotic stresses, fluid flow, and fluid pressures [4]. Due to the charged and hydrated nature of the extracellular matrix, mechanical compression causes exudation of interstitial fluid in cartilage, which alters the osmotic environment of the chondrocytes. Confocal microscopy studies have shown that chondrocytes l
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Nolte, David, Shadia Jalal, and Ran An. "Twin-Neural-Network Differential Autoencoder and Dynamic-Contrast Optical Coherence Tomography for Cancer Diagnostics." In CLEO: Applications and Technology. Washington, D.C.: Optica Publishing Group, 2022. http://dx.doi.org/10.1364/cleo_at.2022.am5i.6.

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Dynamic-contrast optical coherence tomography (OCT) using en face digital holography senses intracellular dynamics in living tumor tissue. Intracellular motions produce ultra-low-frequency Doppler shifts for speeds down to nanometers per second (10 mHz) and up to microns per second (10 Hz). Cancer drugs applied to human tumor biopsies induce changes in these dynamics and produce specific Doppler signatures of therapeutic efficacy. We have developed a new type of deep neural network that performs as a differential autoencoder with high common-mode rejection that isolates Doppler signatures asso
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Mayalu, Michaëlle N., and H. Harry Asada. "Integrated Mechanistic-Empirical Modeling of Cellular Response Based on Intracellular Signaling Dynamics." In ASME 2013 Dynamic Systems and Control Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/dscc2013-3806.

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A hybrid modeling framework integrating a highly specific mechanistic model with highly abstract empirical model is presented. With the growing interest in the scientific and medical community for identification of therapeutic targets in treatment of disease, it is necessary to develop predictive models that can describe cellular behavior in response to environmental cues. Intracellular signaling pathways form complex networks that regulate cellular response in both health and disease. Mechanistic (or white-box) models of biochemical networks are often unable to explain comprehensive cellular
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Shiraishi, Toshihiko, Kazuhiro Sakata, Shin Morishita, and Ryohei Takeuchi. "Investigation of a Cell Mechanosensing System by Measuring Cytoskeletal Deformation and Intracellular Calcium Ion Concentration." In ASME 2011 International Mechanical Engineering Congress and Exposition. ASMEDC, 2011. http://dx.doi.org/10.1115/imece2011-64843.

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This paper describes a method to investigate the relationship between cytoskeletal deformation by mechanical stimulation and its corresponding intracellular signals for identifying mechanosensors of cells. Gene transfection of green fluorescent protein to osteoblasts enabled visualization of actin in cells. When local deformation was applied to a cell by a micropipette, the distribution of cytoskeletal actin deformation in the whole cell was automatically obtained from the two images of the cell before and after deformation by using KLT method. Calcium ion signaling response to the same mechan
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Sun, Xuanhao, Vipuil Kishore, Kateri Fites, and Ozan Akkus. "Mechanically Induced Calcium Release From Bone Matrix Triggers Intracellular Ca2+ Signalling in Osteoblasts: A Novel Mechanotransduction Mechanism." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53446.

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Bone cells are responsible for sensing and converting the mechanical signals into cellular signals to drive bone adaptation and damage repair [1]. Cell-mediated repair of bone is reported to be in preferential association with regions filled with microdamage [2]. Although different theories have been proposed for mechanisms involved in those processes (such as substrate deformation, fluid flow shear, and hydrostatic pressure in mechanotransduction [3], or microcrack and osteocyte apoptosis in damage detection [4]), knowledge on the exact form of physical stimuli which trigger bone cells, espec
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Lages, B., and H. J. Weiss. "TIME DEPENDENCE OF AEQUORIN-INDICATED CALCIUM SIGNALS IN STIMULATED AND UNSTIMULATED PLATELETS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644530.

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The photoprotein aequorin (aeq) has been used as an indicator of intracellular calcium levels ([Ca]i) in platelets (pits). Aeq is believed to monitor aspects of [Ca]i somewhat different from those reported by quin-2, since it reports a higher basal [Ca]i than quin-2 and the presence, rather than the absence, of increased [Ca]i following epinephrine (epi) stimulation. To characterize further aeq-indicated pit Ca signals we measured their time dependence in both stimulated and untimulated pits. Aeq was loaded into pits by membrane permeabilization and resealing at 0°C. The maximum aeq signal (Lm
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Rich, T., N. S. Annamdevula, A. Britain, and S. Leavesley. "PGE1 Triggers Camp Signals Generated at the Plasma Membrane and at Intracellular Locations in Pulmonary Microvascular Endothelial Cells." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a7844.

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Gu, W. Y., W. M. Lai, C. T. Hung, Z. P. Liu, and V. C. Mow. "Analysis of Transient Swelling and Electrical Responses of an Isolated Cell to Sudden Osmotic Loading." In ASME 1997 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1997. http://dx.doi.org/10.1115/imece1997-0292.

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Abstract The cell volume changes in response to changes in the osmolality of an extracellular medium. When the medium osmolality decreases, extracellular water will move into the cell so that the cell volume increases (swelling). The rate of change in cell volume depends on the material properties of the cell, such as the tensile stiffness and hydraulic permeability. During cell swelling, the cell membrane is stretched, possibly affecting membrane permeability to various ions (i.e., stretch-activated ion-channels). The transport of ions and water will result in a change in membrane potential [
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Oswald, Elizabeth S., Pen-hsiu Grace Chao, J. Chloe Bulinski, Gerard A. Ateshian, and Clark T. Hung. "The Role of Microtubule Organization in Chondrocyte Response to Osmotic Loading." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-176634.

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The cytoskeleton, including actin filaments and microtubules, provides chondrocytes with structure, cytoplasmic organization, and intracellular transport. The cytoskeleton is known to be involved in cellular responses to physiologic mechanical and osmotic loading signals, including morphological changes and mechanostransduction [1, 2]. Here, we examine microtubule (MT) involvement in volume response of chondrocytes to osmotic loading, as well as organization of stable MT with hypoosmotic loading. We also explore the hypothesis that chondrocytes from different zones of cartilage possess cytoske
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Reports on the topic "Intracellular signals"

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Bazer, Fuller W., Arieh Gertler, and Elisha Gootwine. Role of Placental Lactogen in Sheep. United States Department of Agriculture, January 2001. http://dx.doi.org/10.32747/2001.7574339.bard.

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Central problems in sheep and dairy cattle production are reproductive failure due to embryonic/fetal mortality and low birth weights, especially in prolific breeds, and reduced milk yields which adversely affect neonatal survival and economy of production. The sheep placenta expresses lactogenic (ovine placental lactogen, oPL) and somatogenic (ovine placental growth hormone, oGH) hormones. Our research has focused on the biological roles of oPL and oGH in function of the uterine endometrium during gestation and the mammary gland during pregnancy and lactation. Major conclusions were that: ( 1
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Horwitz, Benjamin, and Nicole M. Donofrio. Identifying unique and overlapping roles of reactive oxygen species in rice blast and Southern corn leaf blight. United States Department of Agriculture, January 2017. http://dx.doi.org/10.32747/2017.7604290.bard.

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Plants and their fungal pathogens both produce reactive oxygen species (ROS). CytotoxicROS act both as stressors and signals in the plant-fungal interaction. In biotrophs, a compatible interaction generates little ROS, but is followed by disease. An incompatible interaction results in a strong oxidative burst by the host, limiting infection. Necrotrophs, in contrast, thrive on dead and dying cells in an oxidant-rich local environment. Rice blast, Magnaportheoryzae, a hemibiotroph, occurs worldwide on rice and related hosts and can decimate enough rice each year to feed sixty million people. Co
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Avni, Adi, and Gitta L. Coaker. Proteomic investigation of a tomato receptor like protein recognizing fungal pathogens. United States Department of Agriculture, January 2015. http://dx.doi.org/10.32747/2015.7600030.bard.

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Maximizing food production with minimal negative effects on the environment remains a long-term challenge for sustainable food production. Microbial pathogens cause devastating diseases, minimizing crop losses by controlling plant diseases can contribute significantly to this goal. All plants possess an innate immune system that is activated after recognition of microbial-derived molecules. The fungal protein Eix induces defense responses in tomato and tobacco. Plants recognize Eix through a leucine-rich-repeat receptor- like-protein (LRR-RLP) termed LeEix. Despite the knowledge obtained from
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Naim, Michael, Andrew Spielman, Shlomo Nir, and Ann Noble. Bitter Taste Transduction: Cellular Pathways, Inhibition and Implications for Human Acceptance of Agricultural Food Products. United States Department of Agriculture, February 2000. http://dx.doi.org/10.32747/2000.7695839.bard.

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Historically, the aversive response of humans and other mammals to bitter-taste substances has been useful for survival, since many toxic constituents taste bitter. Today, the range of foods available is more diverse. Many bitter foods are not only safe for consumption but contain bitter constituents that provide nutritional benefits. Despite this, these foods are often eliminated from our current diets because of their unacceptable bitterness. Extensive technology has been developed to remove or mask bitterness in foods, but a lack of understanding of the mechanisms of bitterness perception a
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Or, Etti, David Galbraith, and Anne Fennell. Exploring mechanisms involved in grape bud dormancy: Large-scale analysis of expression reprogramming following controlled dormancy induction and dormancy release. United States Department of Agriculture, December 2002. http://dx.doi.org/10.32747/2002.7587232.bard.

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The timing of dormancy induction and release is very important to the economic production of table grape. Advances in manipulation of dormancy induction and dormancy release are dependent on the establishment of a comprehensive understanding of biological mechanisms involved in bud dormancy. To gain insight into these mechanisms we initiated the research that had two main objectives: A. Analyzing the expression profiles of large subsets of genes, following controlled dormancy induction and dormancy release, and assessing the role of known metabolic pathways, known regulatory genes and novel se
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