Log in

Relevant bibliographies by topics / Isoquinoline derivatives / Dissertations / Theses

To see the other types of publications on this topic, follow the link: Isoquinoline derivatives.

Dissertations / Theses on the topic 'Isoquinoline derivatives'

Author: Grafiati

Published: 4 June 2021

Last updated: 27 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 20 dissertations / theses for your research on the topic 'Isoquinoline derivatives.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.

1

McNaught, Kevin St Patrick. "The neurotoxic potential of isoquinoline derivatives structurally related to the Parkinsonism-inducing neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine." Thesis, King's College London (University of London), 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321681.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Charpentier, Langlois Patricia. "Activation d'une réaction entre un acide et une amine par reconnaissance moléculaire. Synthèse d'un récepteur d'amine." Rouen, 1995. http://www.theses.fr/1995ROUES027.

Full text

Abstract:

Notre objectif a été de définir un récepteur hétérocyclique susceptible de faciliter, de manière générale, la réaction entre un acide carboxylique et une amine afin de conduire à un amide. La première partie de ce travail a consisté en l'examen de diverses stratégies d'approche de la partie tricyclique du récepteur. Nous nous sommes notamment intéressés à des dérivés de la tétrahydroisoquinoléine. A cette occasion, nous avons été amenés à apporter une contribution intéressante à la chimie de ce type de dérivés. Dans une seconde partie, nous nous sommes attachés à synthétiser la partie simplifi

APA, Harvard, Vancouver, ISO, and other styles

3

Berk, Mujde. "Development Of New Synthetic Methodologies For Isoquinolone And Isoindolinone Derivatives." Master's thesis, METU, 2010. http://etd.lib.metu.edu.tr/upload/3/12612145/index.pdf.

Full text

Abstract:

ABSTRACT DEVELOPMENT OF NEW SYNTHETIC METHODOLOGIES FOR ISOQUINOLONE AND ISOINDOLINONE DERIVATIVES M&uuml<br>jde, Berk M.Sc., Department of Chemistry Supervisor: Prof. Dr. Metin Balci July 2010, 146 pages Due to the wide range of physiological activities, heterocycles containing nitrogen and oxygen have always attracted the interest of chemists. The objective of this research is to develop new synthetic routes to the synthesis of isoquinolone and isoindolinone derivatives starting from 2-(2-carboxyethyl)benzoic acid and homophthalic acid, respectively. The half ester produced from 2-(2-carboxy

APA, Harvard, Vancouver, ISO, and other styles

4

Liu, Shih-I., and 劉士毅. "Synthesis of Tetrahydroisoquinoline Derivatives Molecular Library and Gold-Assisted Synthesis of Isoquinolino[1,2-a]isoquinoline Derivatives." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/22843163564865086291.

Full text

Abstract:

碩士<br>國立交通大學<br>應用化學系碩博士班<br>105<br>Use Pictet-Spengler reaction to synthesize tetrahydroisoquinoline then react with isocyanate, isothiocyanate, isoselenocyanate via [3 + 2] cycloaddition to obtain imidazo[1,5-b]isoquinoline, or react with chloroacetyl chloride then follow by primary amine to obtain pyraz[1,2-b]isoquinoline, and build up the molecular libraries. Gold-Assisted one-pot two-step synthesis of isoquinolino[1,2-a]isoquinoline. First step undergo Pictet-Spengler reaction, then second step follow by gold catalyze 6-endo-dig cyclization to give the isoquinolino[1,2-a]isoquinoline.

APA, Harvard, Vancouver, ISO, and other styles

5

Yu-Chen, Wu, and 吳育真. "Nickel-Catalyzed Synthesis of Isoquinoline Derivatives." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/91992194016068934547.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Yang, Huei-Ting, and 楊惠婷. "Synthesis of Benzofuran, Fused Isoindolinone and Isoquinoline Derivatives." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/28459742252781734765.

Full text

Abstract:

碩士<br>國立臺灣師範大學<br>化學系<br>104<br>The content of the thesis is divided into two parts. The first part focuses on the chemistry of the nitro alkenes and its application in the synthesis of naphthofuran derivatives. The methodology is based on one-pot base mediated tandem reaction of β-nitrostyrene derivatives and 2-naphthol, 1,4-Michael addition and intramolecular cyclization. A wide variety of naphthofuran derivatives were synthesized in relatively good yields under mild condition. The second part describes about the synthesis of fused isoindolinone and isoquinoline derivatives in two step proc

APA, Harvard, Vancouver, ISO, and other styles

7

Chen, Chih-Jen, and 陳致壬. "Synthesis of Isoquinoline via Aerobic Oxidation of Indene Derivatives." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/h3wbqg.

Full text

Abstract:

碩士<br>中原大學<br>化學研究所<br>102<br>The purpose of this study was to investigate the synthesis of isoquinolines, from indene derivatives with urea and oxygen via one-pot reaction. It was found that the best yield was obtained by using of a 3:2 mixture of 1,4-dioxane and toluene as solvent. Transition metal catalyst was not needed in this reaction. Previausly reported syntheses of isoquinoline derivatives were carried out in acidic conditions or needed a transition metal as catalyst in the reaction. In this research, out method is metal-free and the reaction condition is relativily mild.

APA, Harvard, Vancouver, ISO, and other styles

8

Chen, Ying-Hui, and 陳盈惠. "Novel Synthesis of 1-Phenyl-4-hydroxy-isoquinoline Derivatives." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/z8dggr.

Full text

Abstract:

碩士<br>中國醫藥大學<br>藥學系碩士班<br>101<br>For many years isoquinolines have been an interesting structural class of compounds, and their derivatives, 4-hydroxyisoquinolines, exhibited a range of physiological activities. Due to its wide applications in the field of pharmaceuticals, this type of compounds has attracted our attention. We developed an efficient method to synthesize 4-hydroxy-1-phenylisoquinolines from methyl N-(diphenylmethylene)glycinates via the loss of methanol followed by intramolecular electronic cyclization. A series of 3-substituted 4-hydroxy-1-phenylisoquinolines was synthesized,

APA, Harvard, Vancouver, ISO, and other styles

9

Kuo, Reen-Yen, and 郭荏耘. "Chemical and Biological Studies on the Constituents of Rollinia mucosa Baill. and the Synthesis of Isoquinoline Derivatives." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/84767661870035281015.

Full text

Abstract:

博士<br>高雄醫學大學<br>藥學研究所<br>91<br>In the continuing research of Formosan Annonaceous plants, the methanolic extracts of leaves and stems of Rollinia mucosa Baill. were investigated for their chemical constituents and biological activities, respectively. Fifty-one compounds were isolated including twenty-eight alkaloids, three flavonoids, six lignans, five steroids, one acetogenin, one pyrrole, and seven benzenoids. Among these compounds, eight of them including (-)-artabonatine A (AP-10), romucosine A-D (AP-13~16), promucosine (PA-2), rollipyrrole (PY-1) and romucosine I (PH-1) are isolated as ne

APA, Harvard, Vancouver, ISO, and other styles

10

Wu, Jian-Lin, and 吳建霖. "Quinoline and Isoquinoline Derivatives as Red and Green Phosphorescent Iridium Complexes and Their Application in Organic Electroluminescent Devices." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/92436570960687309743.

Full text

Abstract:

博士<br>國立清華大學<br>化學系<br>97<br>Abstract The thesis includes three parts that focuses on synthesizing various red and green phosphorescent iridium complexes. In the first part, the alkenylquinoline and alkenylisoquinoline derivatives were prepared by two different procedures. The iridium(III) complex cyclometalated with alkenylquinoline or alkenylisoquinoline ligangs as red-light emitters for OLED application. Those complexes show deep red phosphorescent emissions. The optimed device structure is NPB(10nm)/TCTA(20nm)/Dopants(5%):CBP(or o-CzOXD)(30nm)/BCP (10nm)/Alq(50nm)/LiF(1nm)/Al(100nm). When

APA, Harvard, Vancouver, ISO, and other styles

11

Huang, Tzu-Lin, and 黃子霖. "Acid-Promoted Intramolecular Cyclization of Silyl-Protected 2-(3-Arylpropargyltosylaminomethyl)cyclohex-2-en-1-ols－ Synthesis of Isoquinoline Derivatives." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/49709291962998077934.

Full text

Abstract:

碩士<br>國立臺灣師範大學<br>化學系<br>101<br>Lewis acid and TfOH-mediated intramolecular cyclization reaction of tert-butyldimethylsilyl-protected 2-(3-arylpropargyltosylaminomethyl) cyclohex-2-en-1-ols afforded isoquinoline derivatives. 　　The use of BF3•OEt2 for the cyclization/fluorination of silyl-protected 2-(3-arylpropargyltosylaminomethyl)cyclohex-2-en-1-ols produced isoquinoline derivatives containing a C(sp2)-F bond. In this reaction, BF3•OEt2 reacted as both the Lewis acid and the fluoride source. The reaction generates a new C(sp2)-F bond and an octahydroisoquinoline skeleton at ambient temperatu

APA, Harvard, Vancouver, ISO, and other styles

12

Chuang, Sheng-Cheh, and 莊勝絜. "Rhodium-Catalyzed C－H Bond Activation and the Application to the Synthesis of Isoquinoline Derivatives from Hydrazones and Alkynes." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/79627772430231301289.

Full text

APA, Harvard, Vancouver, ISO, and other styles

13

Li, Chien-Le, and 李建樂. "Organic Light-Emitting Diode Materials based on Finite Oligo(arylenevinylene) Derivatives and Iridium-Isoquinoline Complexes: Synthesis, Photochemical Study and Device Application." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/45787269972149221047.

Full text

Abstract:

博士<br>國立清華大學<br>化學系<br>91<br>Part I : A series of oligo(phenylenevinylene) (OPV) derivatives with finite conjugation units were prepared in short steps from few building blocks. The central and terminal aryl groups of these OPV dyes contain a cyano and Ph2N substituents respectively, which affect color of fluorescence. The wavelength ranges from 472 nm (blue) to 614 nm (red) depending on the position of the cyano group. Part II : We report the synthesis and OLED devicesof a series of iridium-phenyl-1- isoquino line complexes with fluoro-substituents on the isoq

APA, Harvard, Vancouver, ISO, and other styles

14

Makelane, Hlamulo Reply. "Regioselectivity of palladium-catalyzed sonogashira cross-coupling of 2-aryl-4-chloro-3-iodoquinoline- derivatives with terminal alkynes." Diss., 2010. http://hdl.handle.net/10500/3838.

Full text

Abstract:

Please note that the structures do not display correctly in the pdf document. Therefore the original manuscript in MSWord has also been uploaded. Please contact us email if you cannot view these files.<br>Sonogashira cross-coupling of 2-aryl-4-chloro-3-iodoquinoline derivatives with stoichiometric amount of terminal alkynes in the presence of bis(triphenylphosphine)palladium(II)chloride and copper iodide in triethylamine afforded the 3-(alkynyl)-2-aryl-4-chloroquinoline, exclusively. On the other hand, the 2-aryl-4-chloro-3-iodoquinolines with excess (2.5 equiv.) of terminal alkynes in the pre

APA, Harvard, Vancouver, ISO, and other styles

15

黃鈺雅. "(一) Lewis Acid-Promoted Intramolecular Cyclization of Silyl- Protected 2-(3-Arylpropargyltosylamino)methylcyclohex- 2-en-1-ols : Synthesis of Isoquinoline Derivatives (二) Brønsted Acid-Assisted Alkyne-Aldehyde Metathesis of 1-(3-Arylprop-2-yn-1-yl)-2-formylpyrrolidine : Synthesis of Pyrrolizine Derivatives". Thesis, 2014. http://ndltd.ncl.edu.tw/handle/09935030685465322120.

Full text

Abstract:

碩士<br>國立臺灣師範大學<br>化學系<br>102<br>This thesis focuses on acid-promoted intramolecular cyclization of N-containing O-silyl-protected enynols and N-containing ynals. Three major reactions are discussed. First, FeCl3-promoted cyclization of O-silyl-protected 2-(3-arylpropargyltosylamino)methylcyclohex-2-en-1-ols in the air at room temperature produced isoquinoline derivatives containing an aryl(chloro)methylene moiety. In this process, FeCl3 acts as both the activating group and the chloride source. Second, BF3-promoted intramolecular cyclization of O-silyl-protected 2-(3-arylpropargyltosylamino)me

APA, Harvard, Vancouver, ISO, and other styles

16

Kuo, Chen-Yuan, and 郭振源. "The Synthesis of Derivatives of 1-Substituted Isoquinolines and Their Biological Activity." Thesis, 2006. http://ndltd.ncl.edu.tw/handle/26822841844904444597.

Full text

Abstract:

博士<br>高雄醫學大學<br>藥學研究所博士班<br>94<br>Isoquinoline alkaloids are interested due to their widespread occurrence in nature and broad biological effects. A series of 1-(2-nitro phenyl)-3,4-dihydroisoquinolines were reduced under very mild reaction conditions in the presence of Tin(Ⅱ) chloride dihydrate (SnCl2.2H2O) to give 5,6-dihydroindazolo[3,2-a]isoquinolines 4a-i. A mechanism for this reaction is proposed and their antitumor activity was evaluated. Besides, phenoxyalkylamino moiety is known to be the mother structure of α-blockers and many benzylisoquimoline- based alkaloids exhibitd excellent an

APA, Harvard, Vancouver, ISO, and other styles

17

MING-CHANG, LIU, and 劉明昌. "Effects of a New Isoquinolinone Derivative on the Action Potentials of Snail Central Neurons." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/26716491765362883193.

Full text

Abstract:

碩士<br>國立臺灣大學<br>藥理學研究所<br>91<br>Effects of BDPBI [ 7-bromo-1,4-dihydro-2-phenyl-4,4-bis( 4-pyridinylmethyl )-2H-isoquinolin-3-one] on the spontaneous action potentials of central neuron of giant African snails (Achatina fulica Ferussac) were studied pharmacologically and electrophysiologically. The RP4, RP2 and LP4 neurons showed a tendency to have a spontaneous firing of action potentials. Extracellular application of BDPBI (>150 μM) elicited burst firing of action potentials in RP4 neuron, but not in LP4 and RP2 neuron. BDPBI (50 μM) did not alter the spontaneous action potentials of RP4 neu

APA, Harvard, Vancouver, ISO, and other styles

18

Liu, Chuan-Che, and 劉全哲. "Cobalt, Nickel and Rhodium Complexes as Catalyst: Synthesis of Indenamine, Indenone, Isoquinolone and Isoindolinone Derivatives Via a Annulation Methodology." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/97231502589951488506.

Full text

Abstract:

博士<br>國立清華大學<br>化學系<br>98<br>In this thesis, we have demonstrated a series of cobalt, nickel and rhodium-catalyzed annulations and their application in organic synthesis are discussed in detail. The thesis is divided into five chapters. The first chapter explains the synthesis of indenamines, indene–enamines and indenones derivatives, the second chapter describes the preparation of indenoisoquinolinones derivatives, the third chapter describes the synthesis of indenones derivatives, the fourth and fifth chapter describes the synthesis of isoquinolone and isoindolinone derivatives. Chapter 1 :

APA, Harvard, Vancouver, ISO, and other styles

19

YANG, YA-AN, and 楊雅安. "Part I、Synthesis of Coumarin-fused Pyrido[2,1-a]isoquinolin-8-ium Heterocycles and Their DerivativesPart II、Multicomponent Synthesis of (3E)-3-[Alkylamino(aryl)methylidene]chroman-2,4-diones and -Nitro Amide Derivatives." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/z6e558.

Full text

Abstract:

碩士<br>東海大學<br>化學系<br>106<br>Part I、Synthesis of Coumarin-fused Pyrido[2,1-a]isoquinolin -8-ium Heterocycles and Their Derivatives Protoberberines are alkaloids that exhibit a wide range of biological activities such as antimicrobial, anti-inflammatory, antimalarial, and antitumor. Previous synthetic efforts have been primarily focused on the biological and therapeutic applications of protoberberines, their intrinsic photochemical properties were much less explored. In this study, a coumarin and pyrido[2,1-a]isoquinolin-8-ium-fused heterocycles were synthesized by p-TsOH-mediated coupling

APA, Harvard, Vancouver, ISO, and other styles

20

Chiu, Wei-Jung, and 邱偉榕. "(1)Catalyst-Controlled Chemodivergent Annulation to Indolo/Pyrrolo- Fused Diazepine and Quinoxaline(2)Metal-catalyzed regioselective synthesis of isoquino [1,2-a] isoquinolines via Aza-Claisen type rearrangement(3)Synthesis of Tetrahydroisoquinoline Heterocyclic Small Molecule Derivatives via Radical Pictet-Spengler Reaction." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/97rybg.

Full text

Abstract:

碩士<br>國立交通大學<br>應用化學系碩博士班<br>107<br>The first part: Compounds containing heteroatoms are the most prominent entities in commercially available drugs that are sold in large quantities.Among all heteroatom molecules, benzimidazole,benzoselenazole, guanidine and pyrrole are considered to be the privileged core of drug and drug discovery.In particular, these biologically important heterocyclic fused/linked heterocyclic molecules are considered to be well known scaffolds in medical and drug discovery research. Therefore, the synthesis of fused and linked heterocyclic molecules must be taken care of

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!