Academic literature on the topic 'L1210-leukemia'

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Journal articles on the topic "L1210-leukemia"

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Saprykina, N. S., L. M. Borisova, M. P. Kiseleva, et al. "Antitumor activity of Ormustine against transplanted leukemia in mice." Russian Journal of Biotherapy 15, no. 2 (2016): 24–31. http://dx.doi.org/10.17650/1726-9784-2016-15-2-24-31.

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Objective: Evaluation of antitumor activity of a novel alkylnitrosoureas derivative Ormustine (an alkylnitrosocarbamoyl L-ornithine) in mouse lymphoid leukemia models. Materials and methods Antitumor activity of Ormustine has been evaluated in B6D2F1 mice with ascites form of leukemia (L1210, L1210/arenosa, L1210/citrullin and P388) and the solid (P388) form. In this study we used preparations from the alkylnitrosourea group: Ormustine, Aranoza and Lizomustine. Treatment of animals was started 24 hours after inoculation of leukemia intraperitoneally, and 48 hours after inoculation subcutaneous
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Miller, Merrill C., Anup Sood, Bernard F. Spielvogel, Ken Bastow, and Iris H. Hall. "Cytotoxic Action of Carboxyborane Heterocyclic Amine Adducts." Metal-Based Drugs 4, no. 4 (1997): 229–41. http://dx.doi.org/10.1155/mbd.1997.229.

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The heterocyclic carboxyborane amines were found to be potent cytotoxic agents in the murine L1210 lymphoid leukemia and human HeLa suspended carcinoma cells. These agents were observed to inhibit HeLa DNA topoisomerase II activity ~ 200 μM and L1210 topoisomerase II activity ≥ 100 μM. These agents did not cause DNA protein linked breaks themselves, but upon incubation for 14-24 hr did enhance the ability of VP-16 to cause cleavable complexes. The heterocyclic amineboranes inhibited DNA synthesis and caused DNA strand scission. They were additive with VP-16 in affording these results as well a
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Chekhun, V. F., A. Mokhir, S. Daum, et al. "PHARMACOLOGICAL EFFECT OF AMINOFERROCENE IN MICE WITH L1210 LEUKEMIA." Experimental Oncology 37, no. 2 (2015): 120–25. http://dx.doi.org/10.31768/2312-8852.2015.37(2):120-125.

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Aim: To study the cytostatic and some biological effects of aminoferrocene using mice with L1210 lymphoid leukemia. Materials and Methods: Experiments were performed on BDF1 male mice (DBA/2, female × C57Bl/6, male) with transplantable L1210 lymphoid leukemia. Determination of antitumor activity of Benzyl-Fc Boron (Bn), it was injected intraperitoneally 6 times daily, starting on day 2 after L1210 leukemia cell transplantation. Doses of Bn such as 26; 260 and 2600 μg/kg were used. The determination of intracellular content of cardiolipin, thiols, reactive oxygen species (ROS) and also analysis
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Kawiak, J., T. Skorski, A. Ciechanowicz, et al. "Cytochemical Characterization of Mouse L1210 Leukemia." Immunological Investigations 17, no. 6-7 (1988): 543–50. http://dx.doi.org/10.3109/08820138809030587.

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Graczyk, Julita, Grzegorz Guzowski, and Izabella Kręźel. "Experimental Studies of the Effect of Cyclic Mitoguazone Analogues on Antineoplastic Activity of Methotrexate." Pteridines 9, no. 4 (1998): 217–21. http://dx.doi.org/10.1515/pteridines.1998.9.4.217.

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Summary In the presented study we tested the effect of the bi- and monocyclic analogues of mitoguazone on neoplastic activity of methotrexate in the model of L1210 leukemia in mice. We have demonstrated that combined therapy involving administration of methotrexate with 2-oxo-propanal bis (4,5,6,7 -tetrahydroIH- l,3-diazepin-2-yl)methylhydrazone dihydroiodide (aM 7) at different doses is more effective than methotrexate monotherapy in mice inoculated with L1210 leukemia.
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Vilpo, J. A., L. M. Vilpo, D. E. Szymkowski, A. O'Donovan, and R. D. Wood. "An XPG DNA repair defect causing mutagen hypersensitivity in mouse leukemia L1210 cells." Molecular and Cellular Biology 15, no. 1 (1995): 290–97. http://dx.doi.org/10.1128/mcb.15.1.290.

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One of the most widely used antitumor drugs is cis-diamminedichloroplatinum(II) (cisplatin), and mechanisms of cisplatin resistance have been investigated in numerous model systems. Many studies have used mouse leukemia L1210/0 as a reference wild-type cell line, and cisplatin-resistant subclones have been derived from it. Increased DNA excision repair capacity is thought to play a key role in the acquired cisplatin resistance, and this has influenced development of drugs for clinical trials. We report here that the L1210/0 line is in fact severely deficient in nucleotide excision repair of da
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Winarno, Hendig, and Ermin Katrin W. "BENZOPHENONE GLUCOSIDE ISOLATED FROM THE ETHYL ACETATE EXTRACT OF THE BARK OF MAHKOTA DEWA [Phaleria macrocarpa (Scheff.) Boerl.] AND ITS INHIBITORY ACTIVITY ON LEUKEMIA L1210 CELL LINE." Indonesian Journal of Chemistry 9, no. 1 (2010): 142–45. http://dx.doi.org/10.22146/ijc.21576.

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Isolation and elucidation of benzophenone glucoside from ethyl acetate extract of Phaleria macrocarpa bark and its inhibitory activity test against leukemia L1210 cell line have been done. The Phaleria macrocarpa bark were macerated using n-hexane, ethyl acetate, and ethanol, respectively. The ethyl acetate extract was then chromatographed on silica gel column and gradiently eluted by n-hexane - ethyl acetate - ethanol with the composition from 20:1:0 until 0:0:1, gave eight fractions. Separation of fraction 6 using semipreparative HPLC on reverse phase column (Capcell Pak C-18 SG120, 15 mm I.
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Katiyar, Arpit, Mahesh Hegde, Sujeet Kumar, et al. "Synthesis and evaluation of the biological activity of N′-[2-oxo-1,2 dihydro-3H-indol-3-ylidene] benzohydrazides as potential anticancer agents." RSC Advances 5, no. 56 (2015): 45492–501. http://dx.doi.org/10.1039/c5ra01528f.

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New N′-[2-oxo-1,2-dihydro-3H-indol-3-ylidene]benzohydrazide derivatives were synthesized and evaluated for their cytotoxic properties against murine leukemia, L1210, human leukemia, REH, K562 and CEM and human cervix carcinoma, HeLa cells.
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Basir, Dasril, and Julinar Julinar. "THE RESTORATIVE COSMETIC CONSTITUENTS OF Fragraea fragrans FRUITS." Indonesian Journal of Chemistry 12, no. 1 (2012): 84–88. http://dx.doi.org/10.22146/ijc.21376.

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This paper describes 3-hydroxyurs-12-en-28-oic acid and its structural isomer 3-hydroxyolean-12-en-28-oic acid isolated from Fragraea fragrans fruits and their biological activities; anti-tumor, anti-inflammation, anti-microbial, and anti-fungal included their ultra violet photo-protective effect after exposed under sunlight radiation. They are useful for cosmetic ingredient. The above triterpenes are very promoting compounds for leukemia L1210 anti-tumor due to limited reports dealing with this type triterpenoid anti-tumor test. They significantly gave IC50 value of 5.78 µg/mL against leukemi
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Brtko, J., P. Filipčík, J. Knopp, and V. Sedláková. "Thyroid hormone responsiveness of the L1210 murine leukemia cell line." Acta Endocrinologica 126, no. 4 (1992): 374–77. http://dx.doi.org/10.1530/acta.0.1260374.

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The presence of saturable and high affinity 3,5,3′-triiodothyronine (T3) binding sites was demonstrated in LI 210 murine leukemia cell nuclei. Scatchard analysis revealed one class of receptors for T3 with Ka = 2.187 × 109l/mol and a maximum binding capacity (Bmax) of 3.96 fmol/106 cells. The effects of T3 on protein phosphorylation and growth rate of L1210 cells were investigated in a medium containing T3-depleted fetal calf serum. T3 was observed to be effective in enhancing protein phosphorylation (153.06%±5.99 sd) compared to cells grown in the absence of T3 (81.49%±13.50 sd). Moreover, in
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Dissertations / Theses on the topic "L1210-leukemia"

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Nsonzi, Frances. "Biophysical studies of the structure-function of alpha-Lactalbumin-Oleic acid complexes cytotoxic against lymphocytic leukemia (L1210 mouse) cell line." Thesis, McGill University, 2014. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=121137.

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Complexes of the bovine whey protein alpha-lactalbumin and oleic acid that have been reported to have cytotoxic effects against tumor cells but not against healthy cells are of potential interest as new ingredients for functional foods. Understanding the relationship between the structures of the protein and lipid in alpha-lactalbumin-oleic acid complexes, as mediated by the conditions employed in their preparation, and their efficacy as cytotoxic agents against tumor cells is an important prerequisite for the production of such ingredients. The overall aim of the present study was to advance
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Sautereau, Anne-Marie. "Etude du mode d'interaction d'antitumoraux de la famille des ellipticines avec les membranes biologiques : role des potentiels de membranes dans les mecanismes d'interaction, d'entree et de cytotoxicite du celiptium chez la bacterie streptococcus." Toulouse 3, 1986. http://www.theses.fr/1986TOU30218.

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Books on the topic "L1210-leukemia"

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Farone, Anthony Louis. Interleukin-2 chemoimmunotherapy of murine L1210 leukemia. 1988.

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Farone, Anthony Louis. Interleukin-2 chemoimmunotherapy of murine L1210 leukemia. 1988.

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Bryson, James Scott. Characteristics of reovirus-mediated chemoimmunotherapy of murine L1210 leukemia. 1985.

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Gowrikanthan, Jayanthi. Cytotoxic responses during chemoimmunotherapy for a murine L1210 leukemia-induced tumor. 1991.

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Farone, Anthony L. Characterization of the immune responses during chemoimmunotherapy of murine L1210 leukemia. 1992.

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Koenigsberg, Adam David. Alpha/Beta and Gamma interferon responses during reovirus-mediated chemoimmunotherapy of L1210 leukemia. 1988.

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Haas, David Gerard. Cytotoxic T lymphocyte and natural killer cell responses following chemoimmunotherapy of murine L1210 leukemia. 1986.

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Baracka, Cheryl Anne. Characterization of the association of reovirus serotype 3 with EL-4 lymphoma and L1210 leukemia cells. 1991.

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Williams, Megan E. Effect of in vitro treatment with BCNU and reovirus on rejection of L1210 leukemia cells by mice. 1985.

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Book chapters on the topic "L1210-leukemia"

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Brown, A. C., and J. D. Lutton. "The Significance of Free Radicals and Free Radical Scavengers in L1210 Leukemia." In Advances in Experimental Medicine and Biology. Springer US, 1988. http://dx.doi.org/10.1007/978-1-4684-5571-7_17.

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Wood, Richard D., Juhani A. Vilpo, Leena M. Vilpo, David E. Szymkowski, Anne O’Donovan, and Jonathan G. Moggs. "Hypersensitivity to Cisplatin in Mouse Leukemia L1210/0 Cells: An XPG DNA Repair Defect." In Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy 2. Springer US, 1996. http://dx.doi.org/10.1007/978-1-4899-0218-4_30.

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Chaney, S. G., S. K. Mauldin, and G. Gibbons. "Biotransformations of Platinum Compounds with the 1,2-Diaminocyclohexane Carrier Ligand in Cultured L1210 Leukemia Cells." In Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy. Springer US, 1988. http://dx.doi.org/10.1007/978-1-4613-1717-3_31.

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"Effects of Polyglutamylation on Folate Cofactor and Antifolate Activity in the Thymidylate Synthase Cycle of Permeabilized Murine Leukemia L1210 Cells." In Montreal, Canada, June 15–20, 1986. De Gruyter, 1986. http://dx.doi.org/10.1515/9783110856262-143.

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Conference papers on the topic "L1210-leukemia"

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Liu, Tuoen, Zech Rios, Peter P. Sheridan, Alok Bhushan, James C. K. Lai, and Christopher Daniels. "Abstract 1720: Tyrosine phosphorylation of HSC70 located in the cell membrane may regulate methotrexate transportation in murine L1210 leukemia cells." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-1720.

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Rodríguez-Borges, J., Liane Saíz-Urra, Yunierkis Pérez-Castillo, et al. "Theoretical Prediction of Antiproliferative Activity against Murine Leukemia Tumor Cell Line (L1210). 3D-Morse Descriptors and its Application in Computational Chemistry." In The 12th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2008. http://dx.doi.org/10.3390/ecsoc-12-01277.

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Reports on the topic "L1210-leukemia"

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Shackelford, M., and R. Tobey. Attempted use of zinc in vivo to protect against nitrogen mustard toxicity in tumor-free and in L1210 leukemia-bearing B6D2F sub 1 mice. Office of Scientific and Technical Information (OSTI), 1989. http://dx.doi.org/10.2172/5404384.

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