Academic literature on the topic 'LASI-DAD'

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Journal articles on the topic "LASI-DAD"

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Lee, Jinkook. "Late-Life Cognition and Dementia in India: New Insights From LASI-DAD." Innovation in Aging 4, Supplement_1 (2020): 659. http://dx.doi.org/10.1093/geroni/igaa057.2277.

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Abstract With more than1.35 billion people, India, the second-most populous country in the world, is soon to experience rapid aging of its population. By2050, India’s older population is projected to reach320 million (about the current size of the entire U.S. population). In this session we introduce the Longitudinal Aging Study in India – Diagnostic Assessment of Dementia (LASI-DAD), a new cohort study designed to advance dementia research to better understand late-life cognition, cognitive aging, cognitive impairment, and dementia, as well as their risk and protective factors. LASI is a pros
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Lee, Jinkook, Pranali Khobragade, Joyita Banerjee, and Sandy Chien. "Design and Methodology of the Longitudinal Aging Study in India—Diagnostic Assessment of Dementia." Innovation in Aging 4, Supplement_1 (2020): 660. http://dx.doi.org/10.1093/geroni/igaa057.2279.

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Abstract Longitudinal Aging Study in India is a nationally representative survey of the health, economic, and social wellbeing of the Indian population aged 45 and older. LASI-DAD is an in-depth study of late-life cognition and dementia, drawing a sub-sample of over 4,000 LASI respondents aged 60 or older. Respondents underwent a battery of cognitive tests, while their informants were interviewed about their cognitive and health conditions. A common set of cognitive tests was selected to enable international comparisons, and additional cognitive tests suitable for illiterate and innumerate pop
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Gross, Alden, Pranali Khobragade, Erik Meijer, and Judith Saxton. "Measurement and Structure of Cognition in the Longitudinal Aging Study in India—Diagnostic Assessment of Dementia." Innovation in Aging 4, Supplement_1 (2020): 660. http://dx.doi.org/10.1093/geroni/igaa057.2280.

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Abstract We tested whether a complex model of human cognitive abilities based on Cattell-Horn-Carroll (CHC) theory, developed in English-speaking samples, adequately describes correlations among tests in the Longitudinal Aging Study in India-Diagnostic Assessment of Dementia (LASI-DAD) (N=3,224). Tests in the neuropsychological battery were chosen for their appropriateness for measuring cognition in older adults in India and suitability for co-calibration with the core LASI survey (N=72,000). We evaluated the factor structure and its conformity with a classical CHC factor model incorporating m
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Jin, Haomiao, Sandy Chien, Erik Meijer, Pranali Khobragade, and Jinkook Lee. "Learning From Clinical Consensus Diagnosis in India to Facilitate Automatic Classification of Dementia: Machine Learning Study." JMIR Mental Health 8, no. 5 (2021): e27113. http://dx.doi.org/10.2196/27113.

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Background The Harmonized Diagnostic Assessment of Dementia for the Longitudinal Aging Study in India (LASI-DAD) is the first and only nationally representative study on late-life cognition and dementia in India (n=4096). LASI-DAD obtained clinical consensus diagnosis of dementia for a subsample of 2528 respondents. Objective This study develops a machine learning model that uses data from the clinical consensus diagnosis in LASI-DAD to support the classification of dementia status. Methods Clinicians were presented with the extensive data collected from LASI-DAD, including sociodemographic in
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Lee, Jinkook, Joyita Banerjee, Pranali Yogiraj Khobragade, Marco Angrisani, and A. B. Dey. "LASI-DAD study: a protocol for a prospective cohort study of late-life cognition and dementia in India." BMJ Open 9, no. 7 (2019): e030300. http://dx.doi.org/10.1136/bmjopen-2019-030300.

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IntroductionAlzheimer’s disease and related dementias can be considered the epidemic of the 21st century. Particularly, the predicted growth in the size of elderly populations in low-income and middle-income countries is expected to produce a dramatic surge in dementia prevalence and incidence. Although a rising burden of dementia presents an urgent challenge for India, previous efforts to study dementia in the country have relied on non-representative samples in geographically restricted regions. The Harmonised Diagnostic Assessment of Dementia for the Longitudinal Aging Study in India (LASI-
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Dhankhar, Anushikha, Pranali Khobragade, Joyita Banerjee, et al. "Methodology of community-based venous blood specimen collection for the harmonized diagnostic assessment of dementia for the Longitudinal Aging Study in India (LASI-DAD): Wave 2." PLOS One 20, no. 7 (2025): e0326917. https://doi.org/10.1371/journal.pone.0326917.

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The prevalence of dementia is on the rise, with 60% of dementia cases existing in low- and middle-income countries. In India, the prevalence was reported to be 7.4%. Since the pathophysiology of dementia is multifactorial, the Harmonized Longitudinal Aging Study in India for the Diagnostic Assessment of Dementia (LASI-DAD) collected data to capture multiple domains, including venous blood specimens (VBS). VBS collection and assays help ascertain the overall health status of an individual, understand disease pathogenesis, and diagnose diseases. In community settings, blood assays also help iden
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Vonk, Jet M. J., Alden L. Gross, Andrea R. Zammit, et al. "Cross-national harmonization of cognitive measures across HRS HCAP (USA) and LASI-DAD (India)." PLOS ONE 17, no. 2 (2022): e0264166. http://dx.doi.org/10.1371/journal.pone.0264166.

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Background As global populations age, cross-national comparisons of cognitive health and dementia risk are increasingly valuable. It remains unclear, however, whether country-level differences in cognitive function are attributable to population differences or bias due to incommensurate measurement. To demonstrate an effective method for cross-national comparison studies, we aimed to statistically harmonize measures of episodic memory and language function across two population-based cohorts of older adults in the United States (HRS HCAP) and India (LASI-DAD). Methods Data for 3,496 HRS HCAP (
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Jayakody, Oshadi, Helena Blumen, and Joe Verghese. "A CROSS-NATIONAL COMPARISON OF RISK FACTORS ASSOCIATED WITH THE MOTORIC COGNITIVE RISK (MCR) SYNDROME." Innovation in Aging 7, Supplement_1 (2023): 284. http://dx.doi.org/10.1093/geroni/igad104.0945.

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Abstract The Motoric Cognitive Risk (MCR) syndrome predicts risk of Alzheimer’s disease and vascular dementia. Cross-national comparisons of risk factors for MCR are important for identifying region-specific factors to design regionally tailored preventive interventions. We examined risk factors associated with MCR in 20,468 adults aged ≥65 years from the U.S Health and Retirement Study (HRS), English Longitudinal Study of Ageing (ELSA), Mexican Health and Aging Study (MHAS), China Health and Retirement Study (CHARLES), Harmonized Diagnostic Assessment of Dementia for the Longitudinal Aging St
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Abu-Amara, Hasan, Wei Zhao, Zheng Li, et al. "Region-Based Analysis with Functional Annotation Identifies Genes Associated with Cognitive Function in South Asians from India." Genes 16, no. 6 (2025): 640. https://doi.org/10.3390/genes16060640.

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Background/Objectives: The prevalence of dementia among South Asians across India is high among those who are 65 years and older, yet little is known about genetic risk factors for dementia in this population. Methods: Using whole-genome sequence data from 2680 participants from the Diagnostic Assessment of Dementia for the Longitudinal Aging Study of India (LASI-DAD), we performed a gene-based analysis on the missense/loss-of-function (LoF) and brain-specific promoter/enhancer variants of 84 genes, previously associated with AD in European Ancestry (EA). These analyses were performed separate
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Pan, Xi, Uma Kelekar, and T. Muhammad. "THE RELATIONSHIP BETWEEN ORAL HEALTH AND COGNITIVE FUNCTION: EVIDENCE FROM THE LASI." Innovation in Aging 7, Supplement_1 (2023): 920. http://dx.doi.org/10.1093/geroni/igad104.2957.

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Abstract The present study aimed to examine the association between oral health and cognitive function among older adults in India. Data for the study were selected from the Longitudinal Aging Survey of India (LASI, 2017-2019) and the LASI Diagnostic Assessment of Dementia (LASI-DAD) and 4,096 respondents aged 60 and above were included. Oral health was measured by self-reported physician-diagnosed oral health problems including presence of painful teeth, ulcers for more than two weeks, bleeding gums, swelling gums, loose teeth, dental cavities or caries, soreness or cracks in the corners of t
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Conference papers on the topic "LASI-DAD"

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Logan, Danielle, AB Dey, Alka Mohan Chutani, et al. "The Development of a Nutrient Database to Analyse the Dietary Intake of Older Indians in the Longitudinal Aging Study in India—Diagnostic Assessment of Dementia (LASI-DAD)." In European Nutrition Conference. MDPI, 2023. http://dx.doi.org/10.3390/proceedings2023091070.

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