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Journal articles on the topic 'LC/MS analysis'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Kim, Jaehyun, Jinhee Kim, Jangmi Hong, et al. "LC–MS/MS analysis of chitooligosaccharides." Carbohydrate Research 372 (May 2013): 23–29. http://dx.doi.org/10.1016/j.carres.2013.02.007.

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2

Hopfgartner, Gérard, Antoine Lesur, and Emmanuel Varesio. "Analysis of biopharmaceutical proteins in biological matrices by LC-MS/MS II. LC-MS/MS analysis." TrAC Trends in Analytical Chemistry 48 (July 2013): 52–61. http://dx.doi.org/10.1016/j.trac.2013.03.008.

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3

Mohammed, Navaziya. "HPLC Hyphenations in Advanced Analytical World." Journal of Physical Chemistry & Biophysics 12, no. 2 (2022): 5. https://doi.org/10.5281/zenodo.14604252.

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Traditional analytical approaches of HPLC found to be insufficient for solving upcoming challenges in species specificity and sensitivity analysis. Modern analytical hybrid techniques which are referred as hyphenations have been introduced from the traditional techniques to overcome the challenges in the analysis of components. Hyphenated approaches combine separation and detection procedures through the use of chromatographic and spectroscopic techniques. The various hyphenations of that are developed until now are LC-MS, LC-NMR, LC-IR, LC-DAD and it also includes multi hyphenations like LC-M

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4

Kerns, Edward H., Kevin J. Volk, Susan E. Hill, and Mike S. Lee. "Profiling new taxanes using LC/MS and LC/MS/MS substructural analysis techniques." Rapid Communications in Mass Spectrometry 9, no. 15 (1995): 1539–45. http://dx.doi.org/10.1002/rcm.1290091514.

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5

Krajčová, A., V. Schulzová, J. Lojza, L. Křížová, and J. Hajšlová. "Phytoestrogens in bovine plasma and milk – LC-MS/MS analysis." Czech Journal of Food Sciences 28, No. 4 (2010): 264–74. http://dx.doi.org/10.17221/138/2010-cjfs.

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Phytoestrogens belong to a group of polyphenolic plant metabolites which induce biological responses, based on their structural similarity to 17&beta;-estradiol. In order to investigate the relationship between the levels of these biologically active compounds and beneficial health effects, it is neccesary to quantify accurately their levels in foods and biological fluids. In this study, HPLC-MS/MS method for the determination of isoflavones genistein, daidzein, and estrogenic metabolite-equol in bovine plasma and milk was optimised and validated. The method allowed low limits of detection

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6

Kobayashi, Hiroko. "Development of Residue Analysis for Pesticides by LC/MS and LC/MS/MS Methods." BUNSEKI KAGAKU 58, no. 12 (2009): 985–97. http://dx.doi.org/10.2116/bunsekikagaku.58.985.

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7

SHIRANE, Yoshiharu. "Environmental Analysis by LC/MS." Journal of Environmental Chemistry 5, no. 3 (1995): 689–92. http://dx.doi.org/10.5985/jec.5.689.

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8

Lu, Xin, Xinjie Zhao, Changmin Bai, Chunxia Zhao, Guo Lu, and Guowang Xu. "LC–MS-based metabonomics analysis." Journal of Chromatography B 866, no. 1-2 (2008): 64–76. http://dx.doi.org/10.1016/j.jchromb.2007.10.022.

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9

Kim, Eun-Hee, Mi-Ra Jang, Jae-Min Shin, et al. "Simultaneous Analysis of Plant Growth Regulators using LC-MS/MS." Korean Journal of Pesticide Science 24, no. 2 (2020): 231–39. http://dx.doi.org/10.7585/kjps.2020.24.2.231.

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10

Radović, Radmila, Bojana Radić, Sanja Đekić, Sanja Belić, and Jovana Kos. "State-of-the-art mycotoxin analysis: Insights from LC/MS-MS method." Food and Feed Research, no. 00 (2025): 73. https://doi.org/10.5937/ffr0-55401.

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Mycotoxins are secondary metabolites produced by fungi, known for their chemical and thermal stability, which makes them resistant to common food and feed processing methods. These toxins can contaminate food and feed, and cause a range of toxic effects upon ingestion, including mutagenic, teratogenic, carcinogenic, immunotoxic, neurotoxic, hepatotoxic, and dermatotoxic effects. In recent years, the application of liquid chromatography combined with tandem mass spectrometry has grown significantly for mycotoxin analysis, owing to its remarkable sensitivity and specificity. Recent literature hi

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11

Song, Miok, Hyunjeong Kim, Eunsun Yun, et al. "Validation of LC-MS/MS and GC-MS/MS based analysis for 7 pesticides using QuEChERS." Korean journal of food science and technology 55, no. 1 (2023): 10–20. http://dx.doi.org/10.9721/kjfst.2023.55.1.10.

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12

Cummings, Jeffrey, Richard Unwin, and Timothy D. Veenstra. "Quantitative analysis of biomarkers by LC–MS/MS." Journal of Chromatography B 877, no. 13 (2009): 1221. http://dx.doi.org/10.1016/j.jchromb.2009.03.001.

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13

Nam, Hye-Seon, Kyong-Hee Nam, Su-Hee Jung, et al. "Analysis of dutasteride in human serum by LC-MS/MS." Analytical Science and Technology 25, no. 1 (2012): 76–82. http://dx.doi.org/10.5806/ast.2012.25.1.076.

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14

Griffiths, William J., and Yuqin Wang. "Analysis of neurosterols by GC–MS and LC–MS/MS." Journal of Chromatography B 877, no. 26 (2009): 2778–805. http://dx.doi.org/10.1016/j.jchromb.2009.05.017.

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15

Medvedovici, Andrei, Karel Lazou, André d'Oosterlinck, Yining Zhao, and Pat Sandra. "Analysis of jojoba oil by LC-coordination ion spray-MS (LC-CIS-MS)." Journal of Separation Science 25, no. 3 (2002): 173–78. http://dx.doi.org/10.1002/1615-9314(20020201)25:3<173::aid-jssc173>3.0.co;2-k.

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16

TSUCHIDA, Sayaka, Takanari HATTORI, Akiko SAWADA, Koretsugu OGATA, Jun WATANABE, and Kazunari USHIDA. "Fecal metabolite analysis of Japanese macaques in Yakushima by LC-MS/MS and LC-QTOF-MS." Journal of Veterinary Medical Science 83, no. 6 (2021): 1012–15. http://dx.doi.org/10.1292/jvms.21-0076.

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17

Dmitrovic, Jasna, and David A. Durden. "Analysis of Fumagillin in Honey by LC-MS/MS." Journal of AOAC INTERNATIONAL 96, no. 3 (2013): 687–95. http://dx.doi.org/10.5740/jaoacint.12-174.

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Abstract An LC/MS/MS method has been optimized and validated for the quantification and confirmation of fumagillin in honey. Fumagillin is isolated and concentrated by RP polymeric SPE. Final extracts are analyzed using electrospray ionization LC/MS/MS in positive mode with a formic acid and ammonium formate–acetonitrile mobile phase. Method uncertainty was determined using two analytical systems from different manufacturers. The validation of this LC/MS/MS method for the detection of fumagillin demonstrated overall recovery of 99.3%, precision of 5.9%, expanded uncertainty of 13.2%, and LOD o

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18

Park, Na-Youn, Eun-Hee Lee, and Younglim Kho. "Analysis Method of Parabens in Human Breast Milk by LC-MS/MS System." Journal of the Korean Chemical Society 60, no. 2 (2016): 118–24. http://dx.doi.org/10.5012/jkcs.2016.60.2.118.

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19

Sherma, Joseph. "High-Performance Liquid Chromatography/Mass Spectrometry Analysis of Botanical Medicines and Dietary Supplements: A Review." Journal of AOAC INTERNATIONAL 86, no. 5 (2003): 873–81. http://dx.doi.org/10.1093/jaoac/86.5.873.

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Abstract This article reviews research on the qualitative and quantitative analysis by high-performance column liquid chromatography/mass spectrometry (LC/MS) and LC/tandem mass spectrometry (LC/MS/MS) of botanical drugs, drug substances or preparations, and finished botanical products. In addition, LC/MS and LC/MS/MS techniques and commercial instruments are described and compared briefly, and prospects for future use of these methods for the analysis of botanicals are suggested. Some applications of direct MS without LC are also described.

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20

Goeringer, Kabrena E., Iain M. McIntyre, and Olaf H. Drummer. "LC-MS Analysis of Serotonergic Drugs." Journal of Analytical Toxicology 27, no. 1 (2003): 30–35. http://dx.doi.org/10.1093/jat/27.1.30.

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21

Lüderwald, I. "Routine analysis with LC-MS coupling?" Fresenius' Zeitschrift für analytische Chemie 323, no. 3 (1986): 287–88. http://dx.doi.org/10.1007/bf00464093.

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22

Pražáková, Kateřina, Vladimír Vrkoslav, Štěpán Strnad, et al. "LC-MS Lipidomic Analysis of Macrophages." Czech Chemical Society Symposium Series 22, no. 2 (2024): 66–69. http://dx.doi.org/10.54779/ccsss20240066.

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Currently, an increasing incidence of cardiovascular diseases is observed in the population. Factors contributing to their development are obesity and pro-inflammatory processes occurring in the adipose tissue. Macrophages, cells of the non-specific immune system, which can be divided into pro-inflammatory and anti-inflammatory, play a significant role in these processes. For a better understanding of these phenomena, it is necessary to analyze the lipidome of macrophages of the two mentioned groups. The presented work was focused on the optimization of selected parameters of the LC-MS method

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23

Riswahyuli, Riswahyuli, Loise RS, and Niza Nemara. "Multi Mycotoxins Analysis in Rice Using LC-MS/MS." MPI (Media Pharmaceutica Indonesiana) 1, no. 2 (2017): 77–84. http://dx.doi.org/10.24123/mpi.v1i2.189.

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Multi mycotoxins analysis in this research has the purpose to develop method of analysisfor rice sample with a simple and fast preparation and novel technology using LC-MS/MS. Several blankrice samples were spiked with standards of 8 classes of mycotoxins (Aflatoxin B1, Aflatoxin B2, AflatoxinG1, Aflatoxin G2, Deoxynivalenol, Zearalenon, T-2, and HT-2). Parameter of linearity, precision, recovery,limit of detection and limit of quantification were obtained and calculated. The result shows that all thevalidation parameters comply with criteria of method validation. Sonication method that was ch

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24

Núñez, Oscar, Encarnación Moyano, and Maria Teresa Galceran. "LC–MS/MS analysis of organic toxics in food." TrAC Trends in Analytical Chemistry 24, no. 7 (2005): 683–703. http://dx.doi.org/10.1016/j.trac.2005.04.012.

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25

Koal, Therese, Diane Schmiederer, Hai Pham-Tuan, Cornelia Röhring, and Manfred Rauh. "Standardized LC–MS/MS based steroid hormone profile-analysis." Journal of Steroid Biochemistry and Molecular Biology 129, no. 3-5 (2012): 129–38. http://dx.doi.org/10.1016/j.jsbmb.2011.12.001.

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26

Mata, A. T., J. P. Ferreira, B. R. Oliveira, et al. "Bottled water: Analysis of mycotoxins by LC–MS/MS." Food Chemistry 176 (June 2015): 455–64. http://dx.doi.org/10.1016/j.foodchem.2014.12.088.

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27

Khoury, Spiro, Corinne Pouyet, Bernard Lyan, and Estelle Pujos-Guillot. "Evaluation of oxidized phospholipids analysis by LC-MS/MS." Analytical and Bioanalytical Chemistry 410, no. 2 (2017): 633–47. http://dx.doi.org/10.1007/s00216-017-0764-1.

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28

Park, Na-Youn, Woong Jung, and Younglim Kho. "Analysis Method of N-Nitrosamines in Human Urine by LC-MS/MS System." Journal of the Korean Chemical Society 61, no. 2 (2017): 51–56. http://dx.doi.org/10.5012/jkcs.2017.61.2.51.

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29

Moon, Ji Young, Hyun Jung Han, Hyemin Dong, et al. "Analysis of LC-MS/MS in Discrimination of the Origin of Commercial Red Ginseng Concentrates." Korean Journal of Food Science and Technology 46, no. 5 (2014): 549–55. http://dx.doi.org/10.9721/kjfst.2014.46.5.549.

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30

Coulot, M., B. Domon, H. Grossenbacher, et al. "LC-MS and MS/MS in the analysis of recombinant proteins." Journal of Molecular Structure 292 (March 1993): 89–103. http://dx.doi.org/10.1016/0022-2860(93)80092-a.

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31

Morikawa, Kouhei, Ken Tanaka, Feng Li, et al. "Analysis of MS/MS Fragmentation of Taxoids." Natural Product Communications 5, no. 10 (2010): 1934578X1000501. http://dx.doi.org/10.1177/1934578x1000501007.

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The fragmentation pathways of seven types of taxoids were investigated by using a LC-MS/MS method, namely: (1) neutral taxoids with a C-4(20) double bond; (2) taxoids with a C-4(20) double bond and oxygenation at C-14; (3) 5-cinnamoyl taxoids with a C-4(20) double bond; (4) a basic taxoid with a C-4(20) double bond; (5) a taxoid with a C-4(20) epoxide; (6) taxoids with an oxetane ring; and (7) taxoids with an oxetane ring and a phenylisoserine C-13 side chain. Depending on the class of core structure and the substitution pattern, each taxoid gave either the molecular adduct ion [M+NH4]+ or [M+

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32

Trifani, Rina, Oren Rabinowitz, Syamsudin Abdillah, and Ernawati Sinaga. "GC-MS and LC-MS/MS Analysis of Bouea macrophylla Fruit Juice." International Journal of Biological, Physical and Chemical Studies 4, no. 2 (2022): 01–10. http://dx.doi.org/10.32996/ijbpcs.2022.4.2.1.

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Bouea macrophylla Griff is a member of the Anacardiaceae family, which has edible fruits. Due to the high nutritional value, appealing taste, and attractive color, the fruit juice of B. macrophylla has the potential to be developed as a functional beverage. The present study was conducted to determine the phytochemical profile of B. macrophylla fruit juice using GC-MS and LC-MS/MS. GC-MS analysis was performed with the Agilent Technologies 7890 Gas Chromatograph with automated sampling and tandem Agilent 5975 Mass Selective Detector and peak analysis with the Chemistation data system. LC-MS/MS

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33

Song, Liguo, Kyoung‐Soo Choi, Young‐Mee Park, et al. "Capillary‐LC‐µESI‐MS/MS and Nano‐LC‐Nano ESI‐MS/MS Analysis Using a Single Binary Pump Capillary LC System: Applications in Proteomics." Journal of Liquid Chromatography & Related Technologies 28, no. 9 (2005): 1271–89. http://dx.doi.org/10.1081/jlc-200054754.

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34

Xu, Mengmeng, Jessica Legradi, and Pim Leonards. "Evaluation of LC-MS and LC×LC-MS in analysis of zebrafish embryo samples for comprehensive lipid profiling." Analytical and Bioanalytical Chemistry 412, no. 18 (2020): 4313–25. http://dx.doi.org/10.1007/s00216-020-02661-1.

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35

Son, Bo-young, Jun-il Kim, Chi-hwa An, Su-won Lee, Bogsoon Kim та Deukmo Chung. "Simultaneous analysis of β-lactam antibiotics and β-blockers by LC-MS/MS". Analytical Science and Technology 29, № 4 (2016): 179–85. http://dx.doi.org/10.5806/ast.2016.29.4.179.

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36

Alfazema, Louisa N., Don S. Richards, Sylvie Gélébart, John C. Mitchell, and Martin J. Snowden. "Rapid, Accurate and Precise Quantitative Drug Analysis: Comparing Liquid Chromatography Tandem Mass Spectrometry and Chip-Based Nanoelectrospray Ionisation Mass Spectrometry." European Journal of Mass Spectrometry 11, no. 4 (2005): 393–402. http://dx.doi.org/10.1255/ejms.772.

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We have developed a liquid chromatography tandem mass spectrometry (LC-MS/MS) system capable of achieving better than 2% accuracy, routinely over a wide concentration range of 1–800 ng mL−1. We demonstrate that the necessary high precision, high accuracy and rapid analysis can be achieved using LC-MS/MS technology. Automated nanoelectrospray ionisation tandem mass spectrometry (nanoESI-MS/MS) technology can be employed to eliminate the chromatographic step completely. In this paper, nanoESI-MS/MS is evaluated and compared directly with LC-MS/MS for the quantitative analysis of two-test analyte

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37

Pang, Bingyao, Ying Zhu, Longqing Lu, Fangbing Gu, and Hailong Chen. "The Applications and Features of Liquid Chromatography-Mass Spectrometry in the Analysis of Traditional Chinese Medicine." Evidence-Based Complementary and Alternative Medicine 2016 (2016): 1–7. http://dx.doi.org/10.1155/2016/3837270.

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With increasingly improved separation of complex samples and detection of unknown material capabilities, liquid chromatography coupled with mass spectrometry (LC-MS) has been widely used in traditional Chinese medicine (TCM) research. This article describes the principles of liquid chromatography (LC) and mass spectrometry (MS) and their advantages and disadvantages in qualitative and quantitative analysis of TCM. We retrieved research literatures about the application of LC-MS in TCM published during the past five years at home and abroad. To better guide the analysis of TCM, this review main

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38

Andrews, Christine L., Andreas Harsch, and Paul Vouros. "Analysis of the in vitro digestion of modified DNA to oligonucleotides by LC–MS and LC–MS/MS." International Journal of Mass Spectrometry 231, no. 2-3 (2004): 169–77. http://dx.doi.org/10.1016/j.ijms.2003.10.005.

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39

Cui, Lijie, Kasem Nithipatikom, and William B. Campbell. "Simultaneous analysis of angiotensin peptides by LC–MS and LC–MS/MS: Metabolism by bovine adrenal endothelial cells." Analytical Biochemistry 369, no. 1 (2007): 27–33. http://dx.doi.org/10.1016/j.ab.2007.06.045.

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40

Zhang, Kai. "Comparison of Flow Injection-MS/MS and LC-MS/MS for the Determination of Ochratoxin A." Toxins 13, no. 8 (2021): 547. http://dx.doi.org/10.3390/toxins13080547.

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Two methods for measuring ochratoxin A in corn, oat, and grape juice were developed and compared. Flow injection (FI) and on-line liquid chromatography (LC) performances were evaluated separately, with both methods using a triple quadrupole tandem mass spectrometer (MS/MS) for quantitation. Samples were fortified with 13C uniformly labeled ochratoxin A as the internal standard (13C-IS) and prepared by dilution and filtration, followed by FI- and LC-MS/MS analysis. For the LC-MS/MS method, which had a 10 min run time/sample, recoveries of ochratoxin A fortified at 1, 5, 20, and 100 ppb in corn,

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41

HAYASHI, Takako, Teruhisa FUJIMAKI, and Maki MIYAZAWA. "Quantitative Analysis of Clenbuterol in Pig Liver by LC-MS/MS/MS." CHROMATOGRAPHY 39, no. 3 (2018): 131–37. http://dx.doi.org/10.15583/jpchrom.2018.011.

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42

Alencar Filho, José M. T. de, Hyany A. P. Teixeira, Pedrita A. Sampaio, et al. "Phytochemical analysis in Alternanthera brasiliana by LC-MS/MS and GC-MS." Natural Product Research 34, no. 3 (2019): 429–33. http://dx.doi.org/10.1080/14786419.2018.1533827.

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43

KAGEYAMA, Naoko, Mina NAKAMURA, Kazutaka SHIMBO, Toshimi MIZUKOSHI, and Hiroshi MIYANO. "Comprehensive Dipeptide Analysis by Pre-column Derivatization LC/MS/MS." BUNSEKI KAGAKU 69, no. 4.5 (2020): 173–78. http://dx.doi.org/10.2116/bunsekikagaku.69.173.

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44

MOCHIZUKI, Naoki, Eri AOKI, Keiko SUGA, Rie ISHII, and Masakazu HORIE. "Analysis of Chloramphenicol in Propolis Extract by LC/MS/MS." Journal of the Food Hygienic Society of Japan (Shokuhin Eiseigaku Zasshi) 49, no. 6 (2008): 399–402. http://dx.doi.org/10.3358/shokueishi.49.399.

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45

MOCHIZUKI, Naoki. "Basic Technology of LC-MS/MS Analysis in Food Safety." Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi) 54, no. 4 (2013): 251–58. http://dx.doi.org/10.3358/shokueishi.54.251.

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46

KAI, Shigemi, Ken ISHIKAWA, Hajime ITO, et al. "Simultaneous Analysis of Oral Antidiabetic Drug by LC-MS/MS." CHROMATOGRAPHY 36, no. 1 (2015): 19–24. http://dx.doi.org/10.15583/jpchrom.2015.003.

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47

Hayano, Toshiya, Yoshio Yamauchi, Kazunobu Asano, et al. "Automated SPR-LC−MS/MS System for Protein Interaction Analysis." Journal of Proteome Research 7, no. 9 (2008): 4183–90. http://dx.doi.org/10.1021/pr700834n.

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48

MOCHIZUKI, Naoki. "Problems on LC-MS/MS Analysis to Ensure Food Safety." YAKUGAKU ZASSHI 131, no. 7 (2011): 1019–25. http://dx.doi.org/10.1248/yakushi.131.1019.

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49

Roach, John A. G., Denis Andrzejewski, Martha L. Gay, David Nortrup, and Steven M. Musser. "Rugged LC-MS/MS Survey Analysis for Acrylamide in Foods." Journal of Agricultural and Food Chemistry 51, no. 26 (2003): 7547–54. http://dx.doi.org/10.1021/jf0346354.

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50

Hauck, Zane Z., Douglas L. Feinstein, and Richard B. van Breemen. "LC–MS-MS Analysis of Brodifacoum Isomers in Rat Tissue." Journal of Analytical Toxicology 40, no. 4 (2016): 304–9. http://dx.doi.org/10.1093/jat/bkw008.

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