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1

Dries, David J. Right ventricle: The neglected neighbor of the left. R.G. Landes, 1994.

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2

Kantor, B. I͡A. Noninvasive diagnostics of the left heart: Biomechanical disturbances. Nova Science Publishers, 1995.

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3

Qiao, Bin, Zhong Min Liu, Yu Guo Weng, and Ajit P. Yoganathan, eds. Surgical Atlas of Functional Single Ventricle and Hypoplastic Left Heart Syndrome. Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-8435-5.

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4

Cosyns, Bernard, Thor Edvardsen, Krasimira Hristova, and Hyung-Kwan Kim. Left ventricle: systolic function. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198726012.003.0020.

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The assessment of left ventricular (LV) systolic function is one of the most important parts of correct diagnosis, selection of treatment strategy or medications, and prediction of prognosis. Although cardiac magnetic resonance imaging is generally accepted as the gold standard in vivo imaging modality for assessing LV systolic function, its practical use is limited due to its limited availability, high cost, and the presence of conditions precluding its performance such as a pacemaker, claustrophobia, and severe arrhythmia. Thus, transthoracic echocardiography is a first-line imaging modality
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5

Smiseth, Otto A., Maurizio Galderisi, and Jae K. Oh. Left ventricle: diastolic function. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198726012.003.0021.

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Evaluation of diastolic function by echocardiography is useful to diagnose heart failure with preserved ejection fraction by showing signs of diastolic dysfunction, and regardless of ejection fraction, echocardiography can be used to estimate left ventricular (LV) filling pressure. Diastolic dysfunction occurs in a number of cardiac diseases other than heart failure and mild diastolic dysfunction is part of the normal ageing process. The fundamental disturbances in diastolic dysfunction are slowing of myocardial relaxation, loss of restoring forces, and reduced LV chamber compliance. As a comp
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6

Zhang, Peng-Fei, Yun Zhang, and Siew Yen Ho. Left ventricle: morphology and geometry. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198726012.003.0018.

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The left ventricle is a cone-shaped muscular pump which receives the blood from the left atrium through the inflow tract and ejects it to the aorta through the outflow tract. The double helical myocardial fibre formation is the basis of efficient motion, function, and morphology of the left ventricle. Physiological or pathological changes of these characteristics of the left ventricle can be evaluated by echocardiography. This chapter describes the morphology and geometry of the left ventricle, including the inflow tract, the outflow tract, double helix formation of left ventricle myocardium,
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7

Donal, Erwan, Seisyou Kou, and Partho Senguptadd. Left ventricle: cardiac mechanics and left ventricular performance. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198726012.003.0019.

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The complexity of left ventricular (LV) function(s) assessment in heart failure patients is related to the complexity of heart anatomy, but also to the complexity of electromechanical interaction, and to the load dependency of all the parameters that could be applied in clinical practice. Three perpendicular axes orienting the global geometry of the LV define the local cardiac coordinate system: radial, circumferential, and longitudinal. Speckle tracking is the technique of choice for quantifying myocardial deformation (regional and global). Longitudinal LV deformation, which is predominantly
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8

Colebourn, Claire, and Jim Newton. The left ventricle in critical illness. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198757160.003.0002.

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This chapter reviews the structure and physiology of the left ventricle and details assessment methods and their safe usage. It looks in detail at the effects of critical illness on left ventricular function, specifically including the effect of sepsis, ischaemia, and drug toxicity.
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9

The effect of oral smokeless tobacco on left ventricular function. 1987.

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10

The effect of oral smokeless tobacco on left ventricular function. 1989.

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11

Nihoyannopoulos, Petros, Gustavo Restrepo Molina, and André La Gerche. Right ventricular dilatation and function. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198726012.003.0048.

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Assessing the right ventricle by any imaging modality is a challenge because of the thin wall and crescent shape that wraps around the left ventricle. Structured echocardiographic examination using two-dimensional imaging provides a detailed regional and global qualitative assessment for routine evaluation. Quantitation is possible using one or more methods including tricuspid annulus plane systolic excursion, fractional area change, and myocardial performance index but speckle tracking deformation imaging and three-dimensional echocardiography are emerging as more robust quantitative methods.
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12

Rosca, Monica, Sergio Mondillo, and Kim O’Connor. Left atrium. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198726012.003.0022.

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The left atrium (LA) in a close interdependence with the left ventricle plays an essential role in the overall cardiovascular performance. The impact of LA remodelling on prognosis and risk stratification has gathered increasing evidence. With advances in imaging technology, the assessment of LA size and function become more accessible and precise. LA volume provides the most accurate estimate of LA size and superior prognostic information. Accounting for complex geometry and motion, three-dimensional echocardiography emerges as the preferred technique for the assessment of dynamic changes in
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13

van den Bosch, Annemien E., Luigi P. Badano, and Julia Grapsa. Right ventricle and pulmonary arterial pressure. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198726012.003.0023.

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Right ventricular (RV) performance plays an important role in the morbidity and mortality of patients with left ventricular dysfunction, congenital heart disease, and pulmonary hypertension. Assessment of RV size, function, and haemodynamics has been challenging because of its complex geometry. Conventional two-dimensional echocardiography is the modality of choice for assessment of RV function in clinical practice. Recent developments in echocardiography have provided several new techniques for assessment of RV dimensions and function, include tissue Doppler imaging, speckle-tracking imaging,
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14

Kantor, B. Ia, N. I. Iabluchanskii, and A. V. Martynenko. Noninvasive Diagnostics of the Left Heart: Biomechanical Disturbances. Nova Science Pub Inc, 1996.

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15

Gonçalves, Alexandra, Pedro Marcos-Alberca, Peter Sogaard, and José Luis Zamorano. Assessment of systolic function. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199599639.003.0008.

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This chapter describes the different modalities for assessment of systolic function by transthoracic echocardiography. Firstly, the basic principles of physiology and the determinants of left ventricular (LV) performance are considered, followed by a systematic appraisal of the methodologies for global LV systolic function assessment. Starting with M-mode echocardiography, passing through the traditional two-dimensional echocardiography evaluation to three-dimensional echocardiography approaches, main strengths and limitations are described. Power Doppler usefulness, regarding stroke volume ca
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16

Myocardial structure and function differences between steroid using and non-steroid using elite powerlifters and endurance athletes. 1992.

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17

Myocardial structure and function differences between steroid using and non-steroid using elite powerlifters and endurance athletes. 1989.

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18

D’Andrea, Antonello, André La Gerche, and Christine Selton-Suty. Systemic disease and other conditions: athlete’s heart. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198726012.003.0055.

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The term ‘athlete’s heart’ refers to the structural, functional, and electrical adaptations that occur as a result of habitual exercise training. It is characterized by an increase of the internal chamber dimensions and wall thickness of both atria and ventricles. The athlete’s right ventricle also undergoes structural, functional, and electrical remodelling as a result of intense exercise training. Some research suggests that the haemodynamic stress of intense exercise is greater for the right heart and, as a result, right heart remodelling is slightly more profound when compared with the lef
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19

Yoganathan, Ajit P., Bin Qiao, Zhong Min Liu, and Yu Guo Weng. Surgical Atlas of Functional Single Ventricle and Hypoplastic Left Heart Syndrome. Springer, 2018.

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20

Yoganathan, Ajit P., Bin Qiao, Zhong Min Liu, and Yu Guo Weng. Surgical Atlas of Functional Single Ventricle and Hypoplastic Left Heart Syndrome. Springer, 2019.

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21

Galderisi, Maurizio, Juan Carlos Plana, Thor Edvardsen, Vitantonio Di Bello, and Patrizio Lancellotti. Cardiac oncology. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198726012.003.0064.

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Cancer therapeutics may induce cardiac damage in the left and the right ventricle. Radiotherapy most frequently induces valvular damage, carotid stenosis, and coronary artery disease. Pericardial disease may be due to both chemo- and radiotherapy. The manifestations of both chemo- and radiotherapy can develop acutely but also become overt years after their performance, in particular after radiotherapy. The main cardiac damage of cancer therapeutics-related cardiac dysfunction (CTRCD) corresponds to the reduction of left ventricular (LV) systolic function. The Expert Consensus document from ASE
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22

Alonso Salinas, Gonzalo Luis, Marina Pascual Izco, Covadonga Fernández-Golfín, Luigi P. Badano, and José Luis Zamorano. Ischaemic heart disease: acute coronary syndrome. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198726012.003.0029.

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Transthoracic echocardiography (TTE) is a non-invasive and accessible tool that should be widely used in the evaluation of patients with suspected or known acute coronary syndrome (ACS). Its role is crucial in the management of patients with suspected ACS without electrocardiographic changes or elevation of cardiac markers, allowing the formulation of differential diagnosis between cardiac and extracardiac aetiologies. If the ACS is confirmed, initial assessment of regional and global left and right ventricle contractile function is fundamental in establishing the management strategy and may h
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23

Sedmera, David, and Robert P. Thompson. Building the cardiovascular system: the acquisition of a functional form. Edited by José Maria Pérez-Pomares, Robert G. Kelly, Maurice van den Hoff, et al. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198757269.003.0013.

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In this chapter we discuss key aspects of heart morphogenesis, namely the formation of the cardiac conduction system, coronary vascularization, and septation. We discuss functional studies and their contribution to our understanding of normal and abnormal development. Finally, we provide some explanations for particular shapes of the left ventricle in different species, reasoning that it is due to combination of physical constrains and functional optimization.
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24

La Canna, Giovanni. Heart valve disease (mitral valve disease): anatomy and morphology of the mitral valve. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198726012.003.0034.

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The mitral valve is a complex anatomical structure that includes the valve tissue (leaflets), the left atrioventricular junction (annulus), and the valve suspension system (chordae tendineae, papillary muscles, and left ventricle). Its functional anatomy can be analysed using two- and three-dimensional transthoracic and transoesophageal echocardiography. Based on certain hallmarks (commissures, clefts), in vivo mitral valve tissue anatomy can be accurately categorized. In addition, three-dimensional reconstruction provides a quantitative model for comprehensive valve analysis. This chapter des
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25

Rigo, Fausto, Covadonga Fernández-Golfín, and Bruno Pinamonti. Dilated cardiomyopathy. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198726012.003.0043.

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Dilated cardiomyopathy (DCM) is characterized by a globally dilated and dysfunctioning left ventricle (LV). Therefore, echocardiographic diagnostic criteria for DCM are a LV end-diastolic diameter greater than 117% predicted value corrected for age and body surface area and a LV ejection fraction less than 45% (and/or fractional shortening less than 25%). Usually, the LV is also characterized by a normal or mildly increased wall thickness with eccentric hypertrophy and increased mass, a spherical geometry (the so-called LV remodelling), a dyssynchronous contraction (typically with left bundle
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