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1

Söderqvist, Emil. "New approaches to monitoring of cardiac function." Doctoral thesis, KTH, Skolan för teknik och hälsa (STH), 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4211.

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Left ventricular pumping performance may be described by intraventricular pressure and volume variables, usually presented as a pressure-volume plot. However, on-line monitoring of left ventricular pressure and volume with high temporal resolution requires the use of an invasive catheter technique such as, for example, the conductance catheter method. On the other hand, the very invasiveness and complexity of this approach makes it less suitable for clinical use. It is then not surprising that there has been long-felt need to make the conductance method less invasive and attempts have been mad
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2

Labombarda, Fabien. "Μyοcardial mechanics and cardiac remοdeling in cοngenital left ventricular οutflοw οbstructiοn Increasing Prevalence of Atrial Fibrillation and Permanent Atrial Arrhythmias in Congenital Heart Disease Left atrial stiffness in corrected congenital left ventricular outflow obstruction Impaired left atrial function in adults and adolescents with corrected aortic coarctation Right Ventricular Strain Impairment in Adults and Adolescents with Repaired Aortic Coarctation". Thesis, Normandie, 2021. http://www.theses.fr/2021NORMC401.

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L’objectif de cette thèse est d'analyser en échocardiographie le remodelage et la fonction cardiaque après correction optimale d’un obstacle congénital du cœur gauche et d’identifier de potentiels marqueurs de risque de survenue de fibrillation atriale. Le premier axe de ce travail est une étude prospective multicentrique qui présente le profil évolutif des arythmies atriales chez les adultes porteurs d’une cardiopathie congénitale. Cette étude démontre l’importance de la fibrillation atriale qui devient l’arythmie prédominante après l’âge de 50 ans chez ces patients. Le deuxième axe de travai
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3

Dodd-o, Jeffrey M. (Jeffrey Michael). "The effects of coronary α₁-adrenergic stimulation on coronary blood flow and left ventricular function". Thesis, University of North Texas, 1991. https://digital.library.unt.edu/ark:/67531/metadc332773/.

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This study examines the α-adrenergic constrictor tone varies with intensity of exercise, the effects of coronary α1-adrenergic blockade on left ventricular contractile function and regional myocardial perfusion, and compares the effects of increasing coronary blood flow by removing α1-constrictor tone.
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4

Sarembock, Ian J. "A sequential evaluation of left ventricular function in asymptomatic and symptomatic patients with chronic severe aortic regurgitation." Doctoral thesis, University of Cape Town, 1987. http://hdl.handle.net/11427/25737.

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The optimal timing of valve replacement surgery in chronic severe aortic regurgitation (AR) has remained a major clinical problem in the management of these patients. Although the onset of symptoms is the generally accepted indication for aortic valve replacement (AVR), the unpredictable development of pre-symptomatic left ventricular (LV) dysfunction as a result of prolonged volume overload has resulted in numerous reports attempting to formulate a risk profile for these patients. Although aortic root and LV cineangiography have been the "gold standard" for defining the severity of AR and its
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5

Meyers, Brett Albert. "Feasibility of Echocardiographic Particle Image Velocimetry for evaluation of cardiac left ventricular filling function." Thesis, Virginia Tech, 2014. http://hdl.handle.net/10919/78159.

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Heart disease is one of the primary causes of morbidity and mortality for the adult population over the age of 65. Furthermore, ailments such as hypertension can affect as many as 50% of the adult population over the age of 45. If left untreated, these ailments eventually precipitate the onset of diastolic dysfunction and heart failure. Diastolic dysfunction is the alteration or impairment of performance in either the left or right ventricle of the heart. Although there has been a marked increase in study of this disease, there is still an apparent difficulty to diagnose patients. Flow visuali
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6

Badano, Luigi P. "Age- and gender-specific reference values for cardiac chamber geometry and function using three-dimensional echocardiography." Doctoral thesis, Università degli studi di Padova, 2014. http://hdl.handle.net/11577/3423660.

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Background. Three-dimensional echocardiography (3DE) enables a comprehensive, accurate and reproducible quantification of cardiac chamber size and function without any geometric assumption about their shape. Superior accuracy and reproducibility of 3DE over stabdard two-dimensional (2DE) approach for cardiac chamber volume measurements in comparison to cardiac magnetic resonance (CMR) has been well documented in a number of studies. Both the European Association of Cardiovascular Imaging and the American Society of Echocardiography recommend 3DE, rather than 2DE, for routine clinical asses
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7

CARAVITA, SERGIO. "Clinical phenotypes, right ventricular function, exercise pathophysiology and outcomes of pulmonary hypertension due to left heart disease: role of the precapillary component." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2019. http://hdl.handle.net/10281/323932.

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Razionale. Nell’ipertensione polmonare (PH), alterazioni sia post- sia pre-capillari possono influire sul postcarico del ventricolo destro (RV), contribuendo alla limitazione della capacità di esercizio, alla disfunzione del RV e alla prognosi. Obiettivi. Caratterizzare l’impatto dell’emodinamica polmonare sul RV, sulla fisiopatologia dell’esercizio e sulla prognosi in pazienti con PH. Metodi. Abbiamo innanzitutto condotto una analisi retrospettiva (2007-2014) presso un centro di riferimento per PH, confrontando pazienti con PH secondaria a malattia del cuore sinistro (LHD) e pazienti con ip
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8

Cioffi, U. "Effects of chronic inflammatory bowel diseases on left ventricular structure and function : dottorato di ricerca in fisiopatologia chirurgica." Doctoral thesis, Università degli Studi di Milano, 2003. http://hdl.handle.net/2434/69556.

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Background: Experimental evidences suggest an increased collagen deposition in inflammatory bowel diseases (IBD). In the hypothesis that chronic inflammation and increased collagen metabolism are reflected also in the systemic circulation, we aimed this study to evaluate the effects on left ventricular wall structure by assessing splanchnic and systemic collagen metabolism (procollagen III), its deposition (ultrasonic tissue characterization), and cardiac function (echocardiography) in patients with different longstanding history of IBD, before and after surgery.Methods: Twenty-seven patients
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9

Koh, Carline, and 許上冕. "Effects of right ventricular pacing and its interruption on left ventricular torsional mechanics and diastolic function in congenitalheart block." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B45167199.

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10

Casero, Cañas Ramón. "Left ventricle functional analysis in 2D+t contrast echocardiography within an atlas-based deformable template model framework." Thesis, University of Oxford, 2008. http://ora.ox.ac.uk/objects/uuid:b17b3670-551d-4549-8f10-d977295c1857.

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This biomedical engineering thesis explores the opportunities and challenges of 2D+t contrast echocardiography for left ventricle functional analysis, both clinically and within a computer vision atlas-based deformable template model framework. A database was created for the experiments in this thesis, with 21 studies of contrast Dobutamine Stress Echo, in all 4 principal planes. The database includes clinical variables, human expert hand-traced myocardial contours and visual scoring. First the problem is studied from a clinical perspective. Quantification of endocardial global and local funct
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11

Jashari, Haki. "The effect of pressure afterload due to aortic coarctation on left ventricular function in children." Doctoral thesis, Umeå universitet, Medicin, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-128126.

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Background: Coarctation of the aorta (CoA) is a congenital heart disease which represents a narrowing of the proximal descending aorta, hence increasing pressure afterload to the left ventricle (LV). Conventional treatment of native CoA is surgical repair, however potential recurrence or other related complications e.g. aortic rupture, heart failure and cerebrovascular events are common. Thus, lifelong follow-up of these patients is required. Echocardiography is the most patient’s friendly method to evaluate CoA and in particular its effect on LV function. Moreover, the novel speckle tracking
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12

Madan, Ashish. "In vitro assessment of the effects of valvular stenosis on aorta hemodynamics and left ventricular function." Wright State University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=wright1527085221854915.

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13

Barbosa, Daniel. "Automated assessment of cardiac morphology and function : An integrated B-spline framework for real-time segmentation and tracking of the left ventricle." Thesis, Lyon, INSA, 2013. http://www.theses.fr/2013ISAL0111.

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L’objectif principal de cette thèse est le développement de techniques de segmentation et de suivi totalement automatisées du ventricule gauche (VG) en RT3DE. Du fait de la nature difficile et complexe des données RT3DE, l’application directe des algorithmes classiques de vision par ordinateur est le plus souvent impossible. Les solutions proposées ont donc été formalisées et implémentées de sorte à satisfaire les contraintes suivantes : elles doivent permettre une analyse complètement automatique (ou presque) et le temps de calcul nécessaire doit être faible afin de pouvoir fonctionner en tem
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14

Marciniak, Anna. "Ventricular function in left-sided regurgitant valve disease : when does the ventricle fail irreversibly? : could this be detected by strain rate echocardiography?" Thesis, St George's, University of London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.511946.

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15

Guzzoni, Vinicius. "Remodelamento da matriz extracelular e respostas cardíacas funcionais em ratos idosos submetidos a treinamento resistido." Universidade Federal de São Carlos, 2016. https://repositorio.ufscar.br/handle/ufscar/7766.

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Submitted by Luciana Sebin (lusebin@ufscar.br) on 2016-09-28T12:49:43Z No. of bitstreams: 1 TeseVG.pdf: 16725561 bytes, checksum: 4a535b068b4ee7e66f0e74094c0f1ed0 (MD5)<br>Approved for entry into archive by Marina Freitas (marinapf@ufscar.br) on 2016-10-10T18:43:03Z (GMT) No. of bitstreams: 1 TeseVG.pdf: 16725561 bytes, checksum: 4a535b068b4ee7e66f0e74094c0f1ed0 (MD5)<br>Approved for entry into archive by Marina Freitas (marinapf@ufscar.br) on 2016-10-10T18:43:12Z (GMT) No. of bitstreams: 1 TeseVG.pdf: 16725561 bytes, checksum: 4a535b068b4ee7e66f0e74094c0f1ed0 (MD5)<br>Made available in DS
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16

Silva, Samuel de Sousa. "Left ventricle functional analysis from coronary CT angiography." Doctoral thesis, Universidade de Aveiro, 2012. http://hdl.handle.net/10773/8077.

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Doutoramento em Engenharia Informática<br>Coronary CT angiography is widely used in clinical practice for the assessment of coronary artery disease. Several studies have shown that the same exam can also be used to assess left ventricle (LV) function. LV function is usually evaluated using just the data from end-systolic and end-diastolic phases even though coronary CT angiography (CTA) provides data concerning multiple cardiac phases, along the cardiac cycle. This unused wealth of data, mostly due to its complexity and the lack of proper tools, has still to be explored in order to asse
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17

Nguyen, Thi-Hong-Minh. "Functional defects and molecular mechanisms of Left Ventricular Noncompaction (LVNC) in Nkx2.5 mutant mice." Thesis, Aix-Marseille, 2016. http://www.theses.fr/2016AIXM4039.

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La LVNC est une cardiomyopathie rare, caractérisée par une hypertrabéculation et de profonds replis du ventricule gauche. A ce jour, nous ne savons toujours pas si la LVNC résulte d'un défaut se produisant durant le développement cardiaque et si sa gravité dépend du stade embryonnaire auquel l'arrêt de la compaction se produit. Notre objectif a été d'étudier l'évolution pathologique de la LVNC en caractérisant les défauts fonctionnels et en identifiant les mécanismes moléculaires dans des modèles de souris présentant un développement anormal des trabécules ventriculaires. Pour établir un modèl
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18

Josse, Matthieu. "L’exercice physique per-dialytique : un rôle cardioprotecteur ?" Electronic Thesis or Diss., Avignon, 2023. http://www.theses.fr/2023AVIG0723.

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Les patients atteints d’insuffisance rénale chronique terminale (IRCT) ont un risque de décès d’origine cardiovasculaire 10 à 30 fois plus élevé que la population saine. L’hémodialyse, essentielle à leur survie, induit en effet des anomalies de contraction segmentaires ventriculaires gauches, certes transitoires mais qui répétées au fil des dialyses contribuent sur le long terme à un remodelage morpho-fonctionnel délétère et à une augmentation du risque d’événements cardiaques majeurs et de mortalité cardiovasculaire. L’exercice physique a été proposé comme une contremesure intéressante, perme
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19

Leung, Dominic Y. C. South Western Sydney Clinical School UNSW. "Exercise and left ventricular function in chronic mitral valve insufficiency." Awarded by:University of New South Wales. South Western Sydney Clinical School, 2002. http://handle.unsw.edu.au/1959.4/18808.

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The projects of this thesis examine the complex interaction between isotonic exercise, functional capacity, exercise-induced myocardial ischaemia, severity of regurgitation and left ventricular function in patients with significant chronic mitral regurgitation. The concept of left ventricular contractile reserve, i.e. the ability of the left ventricle to increase its contractility and decrease its end systolic volume with isotonic exercise, is explored. In patients with chronic isolated mitral regurgitation without coronary disease, isotonic exercise was associated with a slight decrease in le
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20

Grechko, S. I. "Effect of hypertension on the functional state of the left ventricle in patients with stable angina." Thesis, БДМУ, 2017. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/17087.

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21

Read, Philip Alexander. "Investigation of the effect of glucagon-like peptide-1 on left ventricular function during myocardial ischaemia." Thesis, University of Cambridge, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.609154.

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22

Iwanaga, Yoshitaka. "Cardiac Endothelin-1 Plays a Critical Role in the Functional Deterioration of Left Ventricles During the Transition From Compensatory Hypertrophy To Congestive Heart Failure in Salt-Sensitive Hypertensive Rats." Kyoto University, 1999. http://hdl.handle.net/2433/181706.

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23

Gaiotto, Fábio Antonio. "Substituição da valva mitral com tração e fixação dos músculos papilares em pacientes com miocardiopatia dilatada." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/5/5156/tde-02042007-143138/.

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Introdução: A insuficiência cardíaca é uma síndrome clínica grave e freqüente. Nos estágios avançados, pode se apresentar em associação com a insuficiência mitral secundária. O quadro clínico piora e a sobrevida diminui quando a insuficiência mitral está presente. A abordagem cirúrgica da insuficiência mitral secundária tem sido motivo de investigação e a tração quádrupla dos músculos papilares com implante de prótese biológica pode ser uma opção. Objetivo: Avaliar, através da ecocardiografia trans-torácica, a geometria e a função do ventrículo esquerdo após a troca da valva mitral com tração
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24

Leal, Gabriela Nunes. "Estudo ecocardiográfico da função ventricular esquerda em pacientes com lúpus eritematoso sistêmico juvenil através da técnica de Speckle-Tracking bidimensional." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/5/5141/tde-20062016-102845/.

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Objetivo: O principal propósito do estudo foi pesquisar a disfunção ventricular esquerda subclínica em pacientes com lúpus eritematoso sistêmico juvenil (LESJ) através da técnica de speckle-tracking bidimensional. Foi investigada ainda uma possível correlação entre o comprometimento da deformação miocárdica e o SLEDAI-2K (Systemic Lupus Erithematosus Disease Activity Index 2000), bem como a presença de fatores de risco cardiovascular, tanto tradicionais como ligados à doença. Métodos: 50 pacientes assintomáticos do ponto de vista cardiovascular e 50 controles saudáveis (14,74 vs. 14,82 anos, p
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25

Valadão, Tainá Fabri Carneiro. "Impacto do exercício físico combinado na função diastólica de pacientes com insuficiência cardíaca e fração de ejeção reduzida." Botucatu, 2016. http://hdl.handle.net/11449/137985.

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Orientador: Meliza Goi Roscani<br>Resumo: Os efeitos favoráveis de um programa de exercício físico combinado (EFC) em pacientes com insuficiência cardíaca (IC) e fração de ejeção ventricular esquerda reduzida (FEVER) são bem reconhecidos na literatura. Acredita-se que os efeitos benéficos do EF não se devam à melhora da FEVE. Por outro lado, alguns estudos apontaram para efeitos benéficos do EF na função diastólica do VE. Tendo em vista a importância da pressão de enchimento do VE na sintomatologia dos pacientes com IC, levantou-se a hipótese de que de que um programa de EFC e supervisionado é
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26

Lee, Chien-Yi, and 李建沂. "Evaluation of left ventricle ejection function by left ventricle center line." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/8v7958.

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碩士<br>中原大學<br>生物醫學工程研究所<br>107<br>In this study, the shape of left ventricle and the left ventricular function was evaluated. The shape of left ventricle was represented using the flow ejection vector of LV. The performance of LV function was evaluated using the LV ejection fraction of LV. We assume that the LV flow ejection vector of LV will be aligned with the aortic central vector, if the left ventricular function is in its normal, healthy condition. The changes of the LV flow ejection vector will be significantly related to the contraction of myocardium. In this thesis, the cardiac image p
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MASSOLO, ANNA CLAUDIA. "Pulmonary hypertension and cardiac function in congenital diaphragmatic hernia: relationship to disease severity and outcomes." Doctoral thesis, 2019. http://hdl.handle.net/11573/1215973.

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Abstract Objective To assess patterns of postnatal biventricular function and their relationship to prenatal and postnatal markers of disease severity in infants with congenital diaphragmatic hernia (CDH). To investigate clusters of micro RNA as 17-92 expressed in pulmonary hypoplasia in patients with CDH. Study Design Observational case-control study of cardiac function in infants with CDH in the first 5 days of life. Systolic and diastolic function in the right (RV) and left (LV) ventricles were assessed using speckle tracking-derived global strain and tissue Doppler imaging of myo
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28

Krishnamurthy, Ramkumar. "Cardiac MRI: Improved Assessment of Left Ventricular Function, Wall Motion, and Viability." Thesis, 2013. http://hdl.handle.net/1911/71979.

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Heart failure is the clinical syndrome accompanying the inability of the heart to maintain a cardiac output required to meet the metabolic requirements and accommodate venous return, and is one of the leading causes of mortality in United States. Accurate imaging of the heart and its failure is important for successful patient management and treatment. Multiple cardiac imaging modalities provide complementary information about the heart – LV function and wall motion, anatomy, myocardial viability and ischemia. In many instances, it is necessary for a patient to undergo multiple imaging session
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29

Kao, Li-wen, and 高莉玟. "Comparison of Discrimination between Logistic Model with Distance Indicator and Regularized Function for Cardiology Ultrasound in Left Ventricle." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/78010706318240513634.

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碩士<br>國立中山大學<br>應用數學系研究所<br>99<br>Most of the cardiac structural abnormalities will be examined by echocardiography. With more understanding of heart diseases, it is commonly recognized that heart failures are closely related to left ventricular systolic and diastolic functions. This work discusses the association between gray-scale differences and the risk of heart disease from the changes in left ventricular systole and diastole of ultrasound image. Owing to the large dimension of data matrix, following Chen (2011), we also simplify the influence factors by factor analysis and calculate fact
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Huang, Yu-Fang, and 黃于芳. "Study on cardiovascular toxicity of ambient particles in rats with left ventricular dysfunction 1. Decreased left ventricular function in spontaneously hypertensive rats exposed to diesel exhaust particles2. Establishment of a left ventricle-dysfunctio." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/e9v8kn.

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碩士<br>國立臺灣大學<br>職業醫學與工業衛生研究所<br>95<br>Decreased left ventricular function in spontaneously hypertensive rats exposed to diesel exhaust particles Objective: Epidemiologic studies have shown that the death and hospital admissions of heart failure are associated with particulate matter, but the association is not consistent. Resent studies reported that patients with heart failure were more sensitive to particulate matter with median aerodynamic diameter <2.5μg/m3 (PM2.5). Here, we conducted an animal study to further investigate the causal relationship between diesel exhaust particles (DEP) exp
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Huang, Yu-Fang. "Study on cardiovascular toxicity of ambient particles in rats with left ventricular dysfunction 1. Decreased left ventricular function in spontaneously hypertensive rats exposed to diesel exhaust particles 2. Establishment of a left ventricle-dysfunction animal model induced by isoproterenol." 2007. http://www.cetd.com.tw/ec/thesisdetail.aspx?etdun=U0001-3007200711402100.

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Hrdlička, Jaroslav. "Echokardiografické hodnocení systolické funkce levé srdeční komory u potkanů adaptovaných na hypoxii a zvýšenou fyzickou zátěž." Master's thesis, 2013. http://www.nusl.cz/ntk/nusl-321090.

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- 4 - Abstract Adaptation to hypoxia or exercise training has cardioprotective effects against acute ischemic injury, but can potentially negatively influence heart function. Possible negative changes depend on the degree of hypoxia and exercise training intensity. It is therefore necessary to evaluate the effects of the specific adaptation protocols used. The ideal technique is echocardiography, which enables non-invasive, repeated and long-term measurements of the same individual allowing to study the development of changes in the course of adaptation. The aim of this study was to determine
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"Non-invasive assessment of left ventricular diastolic function: the impact of systole on diastole." 2002. http://library.cuhk.edu.hk/record=b6073485.

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Wang Mei.<br>"July 2002."<br>Thesis (Ph.D.)--Chinese University of Hong Kong, 2002.<br>Includes bibliographical references (p. 208-233).<br>Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web.<br>Mode of access: World Wide Web.<br>Abstracts in English and Chinese.
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CHEN, KUAN-YU, and 陳冠宇. "Unsupervised Left Ventricle Segmentation Based on Cardiovascular Magnetic Resonance Imaging for Providing Indicators of Cardiac Functions." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/5538q3.

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碩士<br>輔仁大學<br>資訊工程學系碩士班<br>107<br>Left Ventricle (LV) segmentation is one of the important and challenging task in medical image analysis. Accurate segmentation helps physicians to make the clinical decision for heart dysfunction more easily. One of the most challenging issue for automatic LV segmentation is that the intensity and shape of LV can be similar to other organs in cardiac magnetic resonance imaging (CMRI) which may result into inaccurate LV boundaries. Therefore, in order to provide reliable clinical indices for evaluating cardiac function and diagnosing heart diseases, it is neces
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Medvedev, Roman. "Structural and functional differences between cardiomyocytes from right and left ventricles in health and disease." Doctoral thesis, 2020. http://hdl.handle.net/11562/1017728.

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Several disorders including pulmonary hypertension (PH) and heart failure (HF) could lead to right ventricle (RV) hypertrophy and failure. RV failure is one of the most important prognostic factors for morbidity and mortality in these disorders. However, there is still no therapy to prevent the RV hypertrophy in PH. Treatments developed for the left ventricle (LV) failure do not improve the survival in patients with RV failure probably due to the significant differences in the chambers physiology and hemodynamic function. A better understanding of the cellular and molecular mechanisms of RV hy
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Moberly, Steven Paul. "Impaired cardiovascular responses to glucagon-like peptide 1 in metabolic syndrome and type 2 diabetes mellitus." Thesis, 2013. http://hdl.handle.net/1805/3216.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>Recent advancements in the management of systemic glucose regulation in obesity/T2DM include drug therapies designed to utilize components of the incretin system specifically related to glucagon-like peptide 1 (GLP-1). More recently, GLP-1 has been investigated for potential cardioprotective effects. Several investigations have revealed that acute/sub-acute intravenous administration of GLP-1 significantly reduces myocardial infarct size following ischemia/reperfusion injury and improves cardiac contractile function in the settings o
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Disha, Kushtrim. "New insights into the left ventricular morphological and functional changes in patients with bicuspid aortic valve disease." 2018. https://ul.qucosa.de/id/qucosa%3A32347.

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