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Relevant bibliographies by topics / Liquid Coupled Method (LCM) / Dissertations / Theses

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Dissertations / Theses on the topic 'Liquid Coupled Method (LCM)'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Allard, Erik. "Metabolic Studies with Liquid Separation Coupled to Mass Spectrometry." Doctoral thesis, Uppsala universitet, Analytisk kemi, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-110310.

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Metabolism is the sum of all chemical processes with the purpose to maintain life, as well as enable reproduction, in a living organism. Through the study of metabolism, increased understanding of pharmacological mechanisms and diseases can be achieved. This thesis describes several ways of doing so, including targeted analysis of selected metabolites and investigations of systematic metabolic differences between selected groups through pattern recognition. A method for exploring metabolic patterns in urine samples after intake of coffee or tea was developed. The methodology was later used wit

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2

Arvidsson, Björn. "Quantitative Bioanalysis : Liquid separations coupled to targeted mass spectrometric measurements of bioactive compounds." Doctoral thesis, Uppsala universitet, Analytisk kemi, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8581.

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Performing quantitative analysis of targeted bioactive compounds in biological samples, such as blood plasma, cerebrospinal fluid or extracts from pig liver, put high demands on the ruggedness of the method acquiring the results. In addition to the complexity of the sample matrix, the bioactive compounds targeted for analysis usually have low levels of natural abundance, further increasing the demand on the analytical method sensitivity. Furthermore, quantitation of analytes at trace levels in the presence of large amounts of interfering species in biofluids must aim for repeatable precision,

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3

Owen, Linda Mary Welsh. "Development of a liquid chromatography-inductively coupled plasma mass spectrometry method for zinc specification in an in vitro enzyme digest of cooked food." Thesis, Lancaster University, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.314443.

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4

WANDEKOKEN, FLÁVIA GALVÃO. "DEVELOPMENT OF METHOD FOR THE QUANTIFICATION OF VANADYL PORPHYRINS IN CRUDE OIL FRACTIONS BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY WITH FLOW INJECTION AND INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2016. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=30343@1.

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PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO<br>COORDENAÇÃO DE APERFEIÇOAMENTO DO PESSOAL DE ENSINO SUPERIOR<br>CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO<br>PROGRAMA DE SUPORTE À PÓS-GRADUAÇÃO DE INSTS. DE ENSINO<br>A cromatografia líquida de alta eficiência hifenada por injeção em fluxo com espectrometria de massa com plasma indutivamente acoplado (HPLC-FI-ICP-MS) foi utilizada para investigar vanádio ligado a porfirinas presente em frações de óleo cru. Em primeiro lugar, a amostra de óleo cru foi submetida a um fracionamento por meio de cromatografia líquida prepara

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5

Lee, Kim Chung. "Liquid chromatography coupled with electrospray-ionization mass spectrometry and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry method development and applications for the analysis of food and medicinal herbs." HKBU Institutional Repository, 2009. http://repository.hkbu.edu.hk/etd_ra/995.

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6

Nygren, Yvonne. "Advances in analytical methodologies for studies of the platinum metallome in malignant cells exposed to cisplatin." Doctoral thesis, Umeå universitet, Kemiska institutionen, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-37400.

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The scientific progress about the important chemotherapeutic drug substance cisplatin (CDDP) and its function has often been rendered by data difficult to interpret, and still many questions about its mode of action remains to be clarified by the scientific community. However, studies of CDDP possess a high complexity due to; i) low intracellular concentration, ii) many potential biomolecule targets, iii) poor or unknown stability of the intact drug and its biomolecule adducts and iv) complex and varying sample matrices. Metallomic studies, using advanced analytical techniques may contribute t

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7

Huynh, Huu Hien. "Développement d’une méthode de référence candidate pour la quantification de la procalcitonine dans le sérum humain." Thesis, Université Paris sciences et lettres, 2021. http://www.theses.fr/2021UPSLS037.

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Le dosage de la procalcitonine (PCT) est un outil de choix pour le diagnostic précoce du sepsis et la gestion du traitement antibiotique. Comme les prises de décision médicales et la stratégie de prise en charge thérapeutique des patients reposent en général sur des valeurs seuil de concentration de PCT, il apparaît primordial de disposer de résultats de mesure fiables et comparables, quelle que soit la méthode de dosage employée, dans le temps, et dans l’espace. Or, de nombreuses méthodes de dosage de la PCT de type immunoessai sont actuellement disponibles et les résultats fournis par celles

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8

Catonné, Jean-Claude. "Contribution à l'étude du défaut de sélectivité présenté par les membranes échangeuses d'anions, dans le cadre de leurs applications au traitement électrochimique de régénération des solutions aqueuses d'acides minéraux." Paris 6, 1986. http://www.theses.fr/1986PA066030.

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Essai d'identification de l'origine de la "fuite h+" et de celle des différentes sources susceptibles d'alimenter le mouvement d'eau au sein des membranes échangeuses d'anions, selon que le matériau est fortement ou non "élusterisé", puis d'établissement de l'existence d'une corrélation étroite entre l'intensité de fuite protonique et celle de la perméabilité osmotique des membranes (ainsi que le laisse prévoir la théorie de Gierke dans le cas des membranes échangeuses de cations). Et enfin, évaluation du rôle du champ électrique, ainsi que celui de la composition de l'électrolyte sur les résu

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9

COUSIN, JACKY. "Couplage entre la chromatographie en phase supercritique et la spectrometrie de masse." Paris 6, 1987. http://www.theses.fr/1987PA066776.

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Conception et realisation d'un couplage entre un chromatographe en phase supercritique avec des colonnes capillaires et un spectrometre de masse, en mode d'ionisation chimique. L'appareil cps-sm a ete monte et a ete ensuite applique a l'analyse de substances peu volatiles ou thermosensibles, telles que des hydrocarbures polyaromatiques, des esters d'acides gras, des triglycerides et des peg. Comparaison avec le couplage chromatographie en phase liquide spectrometrie de masse

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10

DUMAS, HERBIN CHRISTINE. "Chromatographie en phase liquide et synthese organique, exemple d'un produit industriel : la cylcododecanone oxime." Paris 6, 1987. http://www.theses.fr/1987PA066104.

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Les techniques de la chromatographie en phase liquide ont permis de mettre au point une separation optimisee des impuretes de la cyclododecanone oxime. La methode la plus performante est la chromatographie de partage a polarite de phases inversee sur un gel de silice greffee octadecyle avec une phase mobile ayant la composition suivante : methanol-acetonitrile-tetrahydrofurane-eau 33:24:3,5:39,5 (v/v). Une trentaine d'impuretes sont ainsi mises en evidence grace a l'emploi d'une colonne de petit calibre de 1 metre de long et de 1 millimetre de diametre interieur. Cette colonne contient 30000 p

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11

Li, Sin-Ling, and 李心羚. "Development and validation of a high performance liquid chromatography coupled with photodiode array detection method for the simultaneous quantification of eight bioactive compounds in functional foods." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/81837094577615870673.

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碩士<br>國立中興大學<br>食品暨應用生物科技學系所<br>103<br>Chlorogenic acid, andrographolide, apigenin, schisandrin, curcumin, sesamin, schisandrin B and tanshinone IIA are bioactive compounds commonly used in functional foods. In the literatures, numerous studies have been attempted to quantify these compounds, mostly focused on single compound examination. In this study, a reversed-phase high performance liquid chromatography (HPLC) method for simultaneous quantification of eight bioactive compounds was developed and validated. A Mightysil RP-18 column was performed with the mobile phase composed of 0.025% (v/v

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12

Chiang, Wen-Chieh, and 江玟潔. "Simple and Rapid Screening Method for the Simultaneous Determination of Urinary VOC Metabolites Using On-line Solid-phase Extraction Coupled with Liquid Chromatography-electrospray Ionization Mass Spectrometry." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/40623325310318179984.

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碩士<br>輔仁大學<br>化學系<br>102<br>Recently, the International Agency for Research on cancer classified outdoor air pollution and particulate matter from outdoor air pollution as carcinogenic to humans (IARC Group 1), based on sufficient evidence of carcinogenicity in humans and experimental animals and strong mechanistic evidence. In particular, a wide variety of volatile organic compounds (VOCs) are volatized or released into the atmosphere and can become ubiquitous, as they originate from many different natural and anthropogenic sources, such as paints, pesticides, vehicle exhausts, cooking fumes,

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13

Wei, Po-Hsien, and 魏伯憲. "Evaluate the Effect on Detecting Vitamin K2-MK7 in the Serum with High-Performance Liquid Chromatography-Tandem Mass Spectrometry Coupled with Electrospray and Atmospheric Pressure Chemical Ionizer and the Method Validation." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/80083825889187417502.

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碩士<br>國立陽明大學<br>環境與職業衛生研究所<br>103<br>The incidence and prevalence of dialysis in Taiwan are keeping at high rates every single year. In accordance with the data from Taiwan's Nation Health Insurance Administration (NHIA) in 2013, the total number of dialysis patients is 66,606 in 2012; the incidence and prevalence of dialysis per million people are 325.0 and 2,833.5 , respectively. Vascular calcification usually occurs to long-term dialysis patients. Some research has found that menaquinone-7 (MK-7) intake is able to prevent dialysis patients from vascular calcification. However, due to the la

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14

Kuo, Chun-Ting, and 郭俊廷. "Part I: Development of a solid phase extraction coupled with high performance liquid chromatography method for the determination of aripiprazole and dehydroaripiprazole in biological fluidPart II: Fingerprint analysis of rhubarb by capillary electrophore." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/03021115787050941796.

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碩士<br>國立臺灣大學<br>藥學研究所<br>97<br>Part I: Development of a solid phase extraction coupled with high performance liquid chromatography method for the determination of aripiprazole and dehydroaripiprazole in biological fluid Aripiprazole is the first drug with dopamine partial agonist effect for schizophrenia. Dehydroaripiprazole is its major metabolite. The determination and validation of aripiprazole and dehydroaripiprazole in human serum and urine were performed by a combination of solid phase extraction (SPE) and high performance liquid chromatography (HPLC) in this study. The method includes t

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15

Chen, Yuan-Chin, and 陳沅情. "1. Rotating hollow fiber-liquid phase microextraction coupled to GC/MS to determine isomers. 2. A rapid quantitative method for pharmacokinetic approach from direct fish analysis by coupling single drop microextraction with AP-MALDI/MS." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/97732595936850596843.

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碩士<br>淡江大學<br>化學學系碩士班<br>95<br>1. A rapid and dynamic liquid phase microextraction technique named Rotating hollow fiber - liquid phase microextraction (RHF-LPME) was developed to couple to GC/MS using electronic ionization (EI) under selective ion monitor (SIM) for quantitative analysis and using self-ion/molecule reaction (SIMR) in conjunction with tandem mass spectrometry for discrimination of five aromatic hydrocarbon isomers including cumene, propylbenzene, 2-ethyltoluene, 1,2,3-trimethylbenzene and 1,2,4-trimethylbenzene. The optimized parameters of this approach was: organic solvent tol

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