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Journal articles on the topic 'Liquid Coupled Method (LCM)'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Mobarak, Mohammad, Bernhard Gatternig, and Antonio Delgado. "On the Simulations of Thermal Liquid Foams Using Lattice Boltzmann Method." Energies 16, no. 1 (2022): 195. http://dx.doi.org/10.3390/en16010195.

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Liquid foams exist in a wide variety of chemical and industrial processes, and they can contaminate the end-product and cause time and economical losses. Understanding and simulating foam is not a straightforward task, due to the highly dispersed time and length scales where the physical phenomena occur. Surfactants’ or proteins’ length scales are far beyond the capability of macroscopic and even mesoscopic numerical fluid solvers, yet the macroscales are still required to be resolved. Meanwhile, the lattice Boltzmann method (LBM) has gained much attention and success as a mesoscopic approach

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2

Du, Kun-ze, Jin Li, Xinrong Guo, Yuhong Li, and Yan-xu Chang. "Quantitative Analysis of Phenolic Acids and Flavonoids in Cuscuta chinensis Lam. by Synchronous Ultrasonic-Assisted Extraction with Response Surface Methodology." Journal of Analytical Methods in Chemistry 2018 (December 20, 2018): 1–10. http://dx.doi.org/10.1155/2018/6796720.

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An effective ultrasonic-assisted extraction method for the separation of phenolic acids and flavonoids in Cuscuta chinensis Lam. was conducted by combining uniform design (UD) coupled with response surface methodology (RSM) and orthogonal design (OD) experiment. A sensitive and selective high-performance liquid chromatography-electrospray ionization tandem triple quadrupole mass spectrometry (HPLC-ESI-MS/MS) method was applied to quantify the sixteen active ingredients (chlorogenic acid, cryptochlorogenic acid, neochlorogenic acid, isochlorogenic acid A, isochlorogenic acid B, isochlorogenic a

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3

LI, ZHI-TAO, GAO-JIN LI, HAI-BO HUANG, and XI-YUN LU. "LATTICE BOLTZMANN STUDY OF ELECTROHYDRODYNAMIC DROP DEFORMATION WITH LARGE DENSITY RATIO." International Journal of Modern Physics C 22, no. 07 (2011): 729–44. http://dx.doi.org/10.1142/s0129183111016580.

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The lattice Boltzmann method (LBM) has been applied to electrohydrodynamics (EHD) in recent years. In this paper, Shan–Chen (SC) single-component multiphase LBM is developed to study large-density-ratio EHD problems. The deformation/motion of a droplet suspended in a viscous liquid under an applied external electric field is studied with three different electric field models. The three models are leaky dielectric model, perfect dielectric model and constant surface charge model. They are used to investigate the effects of the electric field, electric properties of liquids and electric charges.

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Mollee, Peter, Patricia Renaut, Samuel Boros, Dorothy Loo, and Michelle Hill. "Diagnosis Of Amyloidosis Subtype By Laser-Capture Microdissection (LCM) and Tandem Mass Spectrometry (MS) Proteomic Analysis." Blood 122, no. 21 (2013): 5295. http://dx.doi.org/10.1182/blood.v122.21.5295.5295.

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Abstract Aim Correct identification of the protein that is causing amyloidosis is crucial for clinical management. Current standard diagnostic methods have limited ability to detect the full range of amyloid forming proteins. We assessed combining specific sampling of amyloid deposits by LCM and analysis of tryptic digests by tandem MS proteomic analysis to determine whether the majority of amyloidosis clinical samples can be correctly classified as reported by the Mayo Clinic pathology department. Methods We studied 58 cases of well characterised amyloid deposition and 10 cases in which the a

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S., J. Momin*1 S. R. Shahi2 L. P. Jain3 N. D. Kulkarni4 S. S. Gotpagar5 R. M. Savakhande6. "A Concise Review on Hyphenated Techniques: Liquid Chromatography Coupled Mass Spectroscopy (Lc-Ms/Ms)." International Journal of Pharmaceutical Sciences 3, no. 2 (2025): 1856–68. https://doi.org/10.5281/zenodo.14913274.

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Hyphenated techniques combine spectroscopic and chromatographic methods like LC/MS for toxicology, drug monitoring, pharmacokinetic studies, and bioanalysis with interfaces like APCI and ESI for natural product analysis. Mass spectroscopy (MS) is an analytical technique used to determine the m/e ratio of charged analytes, calculate particle masses, and reveal chemical structures using ionization sources. HPLC and mass spectrometry coupling is complex due to high vacuum requirements, but interfaces like TSP, CFAB, API, and ESI overcome this, integrating detectors with liquid chromatographic sep

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Tian, Shuge, Qian Yu, Lude Xin, Zhaohui Sunny Zhou, and Halmuart· Upur. "Chemical Fingerprinting by RP-RRLC-DAD and Principal Component Analysis of Ziziphora clinopodioides from Different Locations." Natural Product Communications 7, no. 9 (2012): 1934578X1200700. http://dx.doi.org/10.1177/1934578x1200700919.

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An efficient and accurate fingerprinting method using reversed-phase rapid-resolution liquid-chromatography coupled with photodiode array detection has been developed and optimized to examine the variance in active compounds among Ziziphora clinopodioides Lam from different locations. Three active components, diosmin, linarin and pulegone, were identified by matching their retention times and UV spectra with the corresponding reference compounds. Our results indicated that chromatographic fingerprints, in combination with principal component analysis (PCA) and hierarchical clustering analysis

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7

Su, Te Cheng, Catherine O'Sullivan, Hideyuki Yasuda, and Christopher M. Gourlay. "Understanding the Rheological Transitions in Semi-Solid Alloys by a Combined <i>In Situ</i> Imaging and Granular Micromechanics Modeling Approach." Solid State Phenomena 327 (January 10, 2022): 127–32. http://dx.doi.org/10.4028/www.scientific.net/ssp.327.127.

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To gain better understanding of rheological transitions from suspension flow to granular deformation and shear cracking, this research conducted shear-deformation on globular semi-solid Al-Cu alloys to study the rheological behavior of semi-solid as a function of solid fraction (38% - 85%) and shear rate (10-4 – 10-1 s-1) under real-time synchrotron radiography observation. By analyzing 17 X-ray imaging datasets, we define three rheological transitions: (i) the critical solid fraction from a suspension to a loosely percolating assembly; (ii) from the net contraction of a loose assembly to the

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8

Riccius, Jörg R., and Evgeny B. Zametaev. "HCF and LCF Analysis of a Generic Full Admission Turbine Blade." Aerospace 10, no. 2 (2023): 154. http://dx.doi.org/10.3390/aerospace10020154.

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A numerical turbine-blade fatigue-life analysis method is suggested. This method comprises a stationary thermal 3D finite element (FE) analysis of the hot run for the combined high-cycle fatigue (HCF) and creep analysis, and a follow-on (one-way coupled) quasi-stationary structural 3D FE analysis (including six load steps) of a single and two half turbine blades and the related disk and rotor section and a (modified Goodman equation based) post-processing fatigue life analysis for the highest HCF-loaded point of the turbine blade. For the low-cycle fatigue (LCF) analysis, this includes a trans

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Mollee, Peter, Patricia Renaut, Samuel Boros, Dorothy Loo, and Michelle Hill. "Diagnosis of Amyloidosis Subtype By Laser-Capture Microdissection (LCM) and Tandem Mass Spectrometry (MS/MS) Proteomic Analysis." Blood 126, no. 23 (2015): 1779. http://dx.doi.org/10.1182/blood.v126.23.1779.1779.

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Abstract Aim Correct identification of the protein that is causing amyloidosis is crucial for clinical management. Current standard laboratory methods have limited ability to detect the full range of amyloid forming proteins. We assessed the diagnostic value of LCM-MS/MS, which combines specific sampling of amyloid deposits by LCM with protein identification by MS/MS. Methods Biopsy specimens were referred to the Princess Alexandra Hospital Amyloidosis Centre. For all specimens, 10µm sections of formalin-fixed paraffin embedded tissue were stained with Congo Red using a standard technique. LCM

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10

Supharoek, Sam-ang, Watsaka Siriangkhawut, Kate Grudpan, and Kraingkrai Ponhong. "A Simple and Reliable Dispersive Liquid-Liquid Microextraction with Smartphone-Based Digital Images for Determination of Carbaryl Residues in Andrographis paniculata Herbal Medicines Using Simple Peroxidase Extract from Senna siamea Lam. Bark." Molecules 27, no. 10 (2022): 3261. http://dx.doi.org/10.3390/molecules27103261.

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A simple and reliable dispersive liquid-liquid microextraction (DLLME) coupled with smartphone-based digital images using crude peroxidase extracts from cassia bark (Senna siamea Lam.) was proposed to determine carbaryl residues in Andrographis paniculata herbal medicines. The method was based on the reaction of 1-naphthol (hydrolysis of carbaryl) with 4-aminoantipyrine (4-AP) in the presence of hydrogen peroxide, using peroxidase enzyme simple extracts from cassia bark as biocatalysts under pH 6.0. The red product, after preconcentration by DLLME using dichloromethane as extraction solvent, w

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11

Meng, Qingyan, Guozhu Li, Bi Luo, Lijun Wang, Yaling Lu, and Wenjie Liu. "Screening and isolation of natural antioxidants from Ziziphora clinopodioides Lam. with high performance liquid chromatography coupled to a post-column Ce(iv) reduction capacity assay." RSC Advances 6, no. 67 (2016): 62378–84. http://dx.doi.org/10.1039/c6ra08588a.

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Hou, Yaqi, Wei Zhang, Jiahua Hu, Feiyu Gao, and Xuexue Zong. "Low Capillary Elastic Flow Model Optimization Using the Lattice Boltzmann Method and Non-Dominated Sorting Genetic Algorithm." Micromachines 16, no. 3 (2025): 298. https://doi.org/10.3390/mi16030298.

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In simulations of elastic flow using the lattice Boltzmann method (LBM), the steady-state behavior of the flow at low capillary numbers is typically poor and prone to the formation of bubbles with inhomogeneous lengths. This phenomenon undermines the precise control of heat transfer, mass transfer, and reactions within microchannels and microreactors. This paper establishes an LBM multiphase flow model enhanced by machine learning. The hyperparameters of the machine learning model are optimized using the particle swarm algorithm. In contrast, the non-dominated sorting genetic algorithm (NSGA-I

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13

Lin, Baofu, Shaoju Guo, Xinxin Hong, et al. "Chemical Characterization and Metabolic Profiling of the Compounds in the Chinese Herbal Formula Li Chang Decoction by UPLC-QTOF/MS." Evidence-Based Complementary and Alternative Medicine 2022 (April 13, 2022): 1–22. http://dx.doi.org/10.1155/2022/1322751.

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Background. Li Chang decoction (LCD), a Chinese medicine formula, is commonly used to treat ulcerative colitis (UC) in clinics. Purpose. This study aimed to identify the major components in LCD and its prototype and metabolic components in rat biological samples. Methods. The chemical constituents in LCD were identified by establishing a reliable ultra-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry (UPLC-QTOF/MS) method. Afterwards, the rats were orally administered with LCD, and the biological samples (plasma, urine, and feces) were collected

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Puderbach, Vanessa, Kilian Schmidt, and Sergiy Antonyuk. "A Coupled CFD-DEM Model for Resolved Simulation of Filter Cake Formation during Solid-Liquid Separation." Processes 9, no. 5 (2021): 826. http://dx.doi.org/10.3390/pr9050826.

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In cake filtration processes, where particles in a suspension are separated by forming a filter cake on the filter medium, the resistances of filter cake and filter medium cause a specific pressure drop which consequently defines the process energy effort. The micromechanics of the filter cake formation (interactions between particles, fluid, other particles and filter medium) must be considered to describe pore clogging, filter cake growth and consolidation correctly. A precise 3D modeling approach to describe these effects is the resolved coupling of the Computational Fluid Dynamics with the

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Zhou, Chongbo, Lingyi Guo, Li Chen, Xin Tian, Tiefeng He, and Qinghua Yang. "Pore-Scale Modeling of Air–Water Two Phase Flow and Oxygen Transport in Gas Diffusion Layer of Proton Exchange Membrane Fuel Cell." Energies 14, no. 13 (2021): 3812. http://dx.doi.org/10.3390/en14133812.

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Understanding multiphase flow and gas transport occurring in electrodes is crucial for improving the performance of proton exchange membrane fuel cells. In the present study, a pore-scale model using the lattice Boltzmann method (LBM) was proposed to study the coupled processes of air–water two-phase flow and oxygen reactive transport processes in porous structures of the gas diffusion layer (GDL) and in fractures of the microscopic porous layer (MPL). Three-dimensional pore-scale numerical results show that the liquid water generation rate is gradually reduced as the oxygen consumption reacti

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Tian, Miao, Zhonglong Lin, Xu Wang, et al. "Pure Ion Chromatograms Combined with Advanced Machine Learning Methods Improve Accuracy of Discriminant Models in LC–MS-Based Untargeted Metabolomics." Molecules 26, no. 9 (2021): 2715. http://dx.doi.org/10.3390/molecules26092715.

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Untargeted metabolomics based on liquid chromatography coupled with mass spectrometry (LC–MS) can detect thousands of features in samples and produce highly complex datasets. The accurate extraction of meaningful features and the building of discriminant models are two crucial steps in the data analysis pipeline of untargeted metabolomics. In this study, pure ion chromatograms were extracted from a liquor dataset and left-sided colon cancer (LCC) dataset by K-means-clustering-based Pure Ion Chromatogram extraction method version 2.0 (KPIC2). Then, the nonlinear low-dimensional embedding by uni

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Zoroddu, Stefano, Angelo Zinellu, Ciriaco Carru, and Salvatore Sotgia. "Analytical Insights into Methods for Measuring Ischemia-Modified Albumin." Molecules 29, no. 19 (2024): 4636. http://dx.doi.org/10.3390/molecules29194636.

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Ischemia-modified albumin (IMA) has emerged as a pivotal biomarker for the early detection of ischemic conditions, particularly myocardial ischemia, where timely diagnosis is crucial for effective intervention. This review provides an overview of the analytical methods for assessment of IMA, including Albumin Cobalt Binding (ACB), Albumin Copper Binding (ACuB), Enzyme-Linked Immunosorbent Assay (ELISA), new techniques such as liquid crystal biosensors (LCB), quantum dot coupled X-ray fluorescence spectroscopy (Q-XRF), mass spectrometry (MS), and electron paramagnetic resonance (EPR) spectrosco

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18

Romagnoli, Francesco, Alessandro Thedy, Baiba Ievina, and Maksims Feofilovs. "Life Cycle Assessment of an Innovative Microalgae Cultivation System in the Baltic Region: Results from SMORP Project." Environmental and Climate Technologies 27, no. 1 (2023): 117–36. http://dx.doi.org/10.2478/rtuect-2023-0010.

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Abstract Microalgae cultivation at biogas plants creates joint benefits for using liquid digestate and exhaust gas from the CHP unit as nutrient and carbon sources for microalgae growing. This circular approach increases biogas production’s sustainability towards a bioeconomy and zero-waste perspective. This study aims to evaluate the potential environmental impacts in connection to a novel microalgae growing technology named Stacked Modular Open Raceway Pond (SMORP) as a side-stream process coupled with centrate and exhaust gases from a biogas plant. A comparative LCA according to ISO 14044 i

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Svyetlichnyy, Dmytro, Michal Krzyzanowski, Robert Straka, Lukasz Lach, and W. Mark Rainforth. "Application of cellular automata and Lattice Boltzmann methods for modelling of additive layer manufacturing." International Journal of Numerical Methods for Heat & Fluid Flow 28, no. 1 (2018): 31–46. http://dx.doi.org/10.1108/hff-10-2016-0418.

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Purpose The holistic numerical model based on cellular automata (CA) and lattice Boltzmann method (LBM) are being developed as part of an integrated modelling approach applied to study the interaction of different physical mechanisms in laser-assisted additive layer manufacturing (ALM) of orthopaedic implants. Several physical events occurring in sequence or simultaneously are considered in the holistic model. They include a powder bed deposition, laser energy absorption and heating of the powder bed by the moving laser beam, leading to powder melting or sintering, fluid flow in the melted poo

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20

Cheng, Ming, Jiali He, Yu Gu, et al. "Changes in Phenolic Compounds and Antioxidant Capacity of Artocarpus heterophyllus Lam. (Jackfruit) Pulp during In Vitro Gastrointestinal Digestion." Antioxidants 13, no. 1 (2023): 37. http://dx.doi.org/10.3390/antiox13010037.

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An in vitro gastrointestinal digestion model was applied to investigate the effect of digestion on the phenolic compounds and antioxidant capacity of Artocarpus heterophyllus Lam. (jackfruit) pulp. The total phenol content (TPC) was determined using Folin–Ciocalteu method, and the antioxidant activities were evaluated by DPPH and ABTS assays. Phenolic compounds were analyzed using ultra-performance liquid chromatography coupled with electrospray ionization, followed by quadrupole time-of-flight mass spectrometry (UPLC-ESI-Q-TOF-MS/MS). The results showed that TPC was significantly higher after

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Vorspohl, J., L. Burchardt, M. Meinke, A. Brümmer, and W. Schröder. "High-resolution simulations of gas-liquid Couette-type sealing gap flows." IOP Conference Series: Materials Science and Engineering 1322, no. 1 (2024): 012004. https://doi.org/10.1088/1757-899x/1322/1/012004.

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Abstract The two-phase flow in sealing gaps of twin-screw compressors is investigated using highly resolved coupled multiphase simulations. Oil-injected rotary-type positive displacement compressors (RPDC) such as twin-screw machines are used for the compression of refrigerants in HVAC (Heating, Ventilation, and Air Conditioning) systems. The efficiency of such machines is largely determined by the inevitable two-phase surge and gap flows. The simulation of flows in such compressors is still a challenge due to the complexity of the two-phase flow in the narrow gaps (<0.3mm) with organic wor

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Villarreal Romero, Wilson Leonardo, Jorge Eliecer Robles Camargo, and Geison Modesti Costa. "Phytochemical Standardization of an Extract Rich in Flavonoids from Flowers of Kalanchoe pinnata (Lam) Pers." Scientia Pharmaceutica 91, no. 4 (2023): 50. http://dx.doi.org/10.3390/scipharm91040050.

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Kalanchoe pinnata is a species widely used in traditional medicine in Latin America and southern Africa. This species has been reported to have different activities, such as antioxidant, anti-inflammatory, and cytotoxic, the latter being related to its flavonoid content. The aim of this study was to contribute to the standardization of the aqueous extract of flowers from Kalanchoe pinnata. Purification of chemical markers was carried out by centrifugal partition chromatography (CPC). Stability tests under stress conditions were conducted for the extract by using the chromatographic profiles an

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Su, Yanwen, Xuelin Tang, Fujun Wang, Xiaoqin Li, and Xiaoyan Shi. "Three-Dimensional Cavitation Bubble Simulations based on Lattice Boltzmann Model Coupled with Carnahan-Starling Equation of State." Communications in Computational Physics 22, no. 2 (2017): 473–93. http://dx.doi.org/10.4208/cicp.oa-2016-0112.

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AbstractThe Shan-Chen multiphase lattice Boltzmann model (LBM) coupled with Carnahan-Starling real-gas equation of state (C-S EOS)was proposed to simulate three-dimensional (3D) cavitation bubbles. Firstly, phase separation processes were predicted and the inter-phase large density ratio over 2×104was captured successfully. The liquid-vapor density ratio at lower temperature is larger. Secondly, bubble surface tensions were computed and decreased with temperature increasing. Thirdly, the evolution of creation and condensation of cavitation bubbles were obtained. The effectiveness and reliabili

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Rao, Sai Sashankh, and Harris Wong. "The motion of long drops in rectangular microchannels at low capillary numbers." Journal of Fluid Mechanics 852 (August 2, 2018): 60–104. http://dx.doi.org/10.1017/jfm.2018.521.

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Drop flow in rectangular microchannels has been utilized extensively in microfluidics. However, the pressure-gradient versus flow-rate relation is still not well understood. We study the motion of a long drop in a rectangular microchannel in the limit the capillary number $Ca\rightarrow 0$ ($Ca=\unicode[STIX]{x1D707}U/\unicode[STIX]{x1D70E}$, where $U$ is the constant drop velocity, $\unicode[STIX]{x1D707}$ is the viscosity of the carrier liquid and $\unicode[STIX]{x1D70E}$ is the interfacial tension). In this limit, the moving drop looks like the static drop and has two end caps connected by

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Dimitrienko, Yu, S. Karimov, and D. Kolzhanova. "Coupled micro-macroscopic modeling of layered composites with finite deformations." E3S Web of Conferences 376 (2023): 01030. http://dx.doi.org/10.1051/e3sconf/202337601030.

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A coupled micro- and macroscopic modeling of an incompressible layered composite material under finite deformations is performed based on the asymptotic homogenization method and universal semi-linear models. The deformation diagrams of the periodicity cell are calculated. A method for searching for effective transversally isotropic properties of LCM based on the obtained diagrams is considered. Cylindrical bending of an LCM plate is simulated using the model of a transversally isotropic medium. The microstresses in the periodicity cell are calculated based on the homogenized stresses.

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Azonsivo, Rufine, Kelly Cristina Oliveira de Albuquerque, Ana Laura Gadelha Castro, et al. "Cytotoxicity and Genotoxicity Evaluation of Zanthoxylum rhoifolium Lam and In Silico Studies of Its Alkaloids." Molecules 28, no. 14 (2023): 5336. http://dx.doi.org/10.3390/molecules28145336.

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The alkaloids isolated from Zanthoxylum rhoifolium have demonstrated great pharmacological potential; however, the toxic profiles of these extracts and fractions are still not well elucidated. This study evaluated the toxicity of the ethanol extract (EEZR) and neutral (FNZR) and alkaloid (FAZR) fractions. Chemical characterization was performed by chromatographic methods: thin-layer chromatography (TLC) and high-performance liquid chromatography coupled with diode array detection (HPLC–DAD). The cytotoxicity of the samples was evaluated in human hepatocellular carcinoma (HepG2) cells using the

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Feng, Yi, Gao Li, Yingfeng Meng, and Boyun Guo. "A Novel Approach to Investigating Transport of Lost Circulation Materials in Rough Fracture." Energies 11, no. 10 (2018): 2572. http://dx.doi.org/10.3390/en11102572.

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The drilling fluid loss or lost circulation via fractures is one of the critical engineering problems in the development of deep oil and gas resources. The conventional treatment is to introduce granular lost circulation material (LCM) into the drilling fluid system to plug fractures. In this work, a method incorporating the fracture surface scanning technique and coupled Computational Fluid Dynamics-Discrete Element Method (CFD-DEM) numerical simulation is proposed for the first time to investigate how the LCM particles plug rough fractures. The rough fracture model is built utilizing a high

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Roy, Anirban, Frida H. Roenning, Yu-Kai Weng, Douglas S. Aaron, Jacob A. Wrubel, and Matthew M. Mench. "An Advanced Allen-Cahn Navier-Stokes Coupled Lbm Model to Predict Two-Phase Flow Dynamics at the Pore-Scale inside a Polymer Electrolyte Water Electrolyzer." ECS Meeting Abstracts MA2024-02, no. 45 (2024): 3163. https://doi.org/10.1149/ma2024-02453163mtgabs.

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Polymer Electrolyte Water Electrolyzers (PEWEs) stand as promising energy storage solutions, leveraging variable renewable energy sources to produce hydrogen. Simulating the intricate two-phase fluid dynamics within these systems necessitates the use of complex numerical models since direct experimentation to capture these dynamics is difficult. Currently, most models adopt a macroscopic continuum approach. However, integrating various modeling scales, especially coupling two-phase flow interactions between channels and the porous media within such systems, remains challenging1. This works att

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Lee, C. F., S. I. Jeng, and M. T. Liu. "Temperature and Frequency Modified Fatigue Initiation Life of Solder Alloys Predicted by Endochronic Cyclic Damage-Coupled Viscoplasticity." Journal of Mechanics 27, no. 2 (2011): 267–77. http://dx.doi.org/10.1017/jmech.2011.30.

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ABSTRACTIn this paper, an evolution equation of cyclically internal damage in the intrinsic damage time scale after the threshold cycles N0 was extended by employing its damage parameters proposed to be dependent of frequency (v) and temperature (T) under cyclic fatigue loading. The resulting damage-coupled endochronic viscoplasticity can drive v and T modified power form equations of cyclic damage and its fatigue initiation life = N1 + N0. Under fatigue tests with T effect and N0 = 0, the power form equation of N1(T)/(Th), named as T-LCM (T modified Lee Coffin-Manson) equation for fatigue ini

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Gantois, Renaud, Arthur Cantarel, Gilles Dusserre, Jean Noel Félices, and Fabrice Schmidt. "Mold Filling Simulation of Resin Transfer Molding Combining BEM and Level Set Method." Applied Mechanics and Materials 62 (June 2011): 57–65. http://dx.doi.org/10.4028/www.scientific.net/amm.62.57.

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Liquid Composite Molding (LCM) is a popular manufacturing process used in many industries. In Resin Transfer Molding (RTM), the liquid resin flows through the fibrous preform placed in a mold. Numerical simulation of the filling stage is a useful tool in mold design. In this paper the implemented method is based on coupling a Boundary Element Method (BEM) with a Level Set tracking. The present contribution is a two-dimensional approach, decoupled from kinetics, thermal analysis and reinforcement deformation occurring during the flow. Applications are presented and tested, including a flow clos

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Gantois, Renaud, Arthur Cantarel, Jean Noel Félices, Nicolas Pirc, and Fabrice Schmidt. "BEM Simulation of 3D Updated Resin Front for LCM Processes." Key Engineering Materials 446 (July 2010): 131–36. http://dx.doi.org/10.4028/www.scientific.net/kem.446.131.

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The use of composite materials in large structures has increased in recent years. Aircraft industry has recently begun to investigate the field of Liquid Composite Molding (LCM) through research programs because of its ability to produce large parts at low cost. The present paper focuses on modeling a 3D radial impregnation through an anisotropic fibrous perform. As a preliminary work, it is assumed an isothermal flow and no hydro-mechanical coupling. Governing equations are Darcy’s law and mass conservation. Simulation is performed combining Boundary Element Method (BEM) with a lagrangian mov

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Schwenkel, Johannes, and Björn Maronga. "Towards a Better Representation of Fog Microphysics in Large-Eddy Simulations Based on an Embedded Lagrangian Cloud Model." Atmosphere 11, no. 5 (2020): 466. http://dx.doi.org/10.3390/atmos11050466.

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The development of radiation fog is influenced by multiple physical processes such as radiative cooling and heating, turbulent mixing, and microphysics, which interact on different spatial and temporal scales with one another. Once a fog layer has formed, the number of fog droplets and their size distribution have a particularly large impact on the development of the fog layer due to their feedback on gravitational settling and radiative cooling at the fog top, which are key processes for fog. However, most models do not represent microphysical processes explicitly, or parameterize them rather

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Zhang, Yuhe, Xiuxiu Wang, Wenlong Yang, et al. "Programmable Complex Shape Changing of Polysiloxane Main-Chain Liquid Crystalline Elastomers." Molecules 28, no. 12 (2023): 4858. http://dx.doi.org/10.3390/molecules28124858.

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Liquid crystal elastomers (LCEs) are shape-morphing materials whose large and reversible shape transformations are caused by the coupling between the mobile anisotropic properties of liquid crystal (LC) units and the rubber elastic of polymer networks. Their shape-changing behaviors under certain stimuli are largely directed by the LC orientation; therefore, various strategies have been developed to spatially modulate the LC alignments. However, most of these methods are limited as they require complex fabrication technologies or have intrinsic limitations in applicability. To address this iss

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Alotaibi, Hatim, Constantinos Soutis, Dianyun Zhang, and Masoud Jabbari. "A Numerical Framework of Simulating Flow-Induced Deformation during Liquid Composite Moulding." Journal of Composites Science 8, no. 10 (2024): 401. http://dx.doi.org/10.3390/jcs8100401.

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Fibre deformation (or shearing of yarns) can develop during the liquid moulding of composites due to injection pressures or polymerisation (cross-linking) reactions (e.g., chemical shrinkage). On that premise, this may also induce potential residual stress–strain, warpage, and design defects in the composite part. In this paper, a developed numerical framework is customised to analyse deformations and the residual stress–strain of fibre (at a micro-scale) and yarns (at a meso-scale) during a liquid composite moulding (LCM) process cycle (fill and cure stages). This is achieved by linking flow

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Li, Ying, Brian Via, Qingzheng Cheng, and Yaoxiang Li. "Lifting Wavelet Transform De-noising for Model Optimization of Vis-NIR Spectroscopy to Predict Wood Tracheid Length in Trees." Sensors 18, no. 12 (2018): 4306. http://dx.doi.org/10.3390/s18124306.

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The data analysis of visible-near infrared (Vis-NIR) spectroscopy is critical for precise information extraction and prediction of fiber morphology. The objectives of this study were to discuss the de-noising of Vis-NIR spectra, taken from wood, to improve the prediction accuracy of tracheid length in Dahurian larch wood. Methods based on lifting wavelet transform (LWT) and local correlation maximization (LCM) algorithms were developed for optimal de-noising parameters and partial least squares (PLS) was employed as the prediction method. The results showed that: (1) The values of tracheid len

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Ahmed Ouezgan, Mouad Bellahkim, Said Adima, Aziz Maziri, El Hassan Mallil, and Jamal Echaabi. "Resin Film Infusion Process: Numerical Algorithm." Journal of Advanced Research in Fluid Mechanics and Thermal Sciences 90, no. 2 (2022): 20–31. http://dx.doi.org/10.37934/arfmts.90.2.2031.

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The liquid composite molding (LCM) belongs to the composite manufacturing processes. In this family, a fabric preform material is placed into the mold cavity, and then it is impregnated with a thermosetting resin of low viscosity, until the fiber skeleton is entirely filled and finally polymerized to create a polymeric composite product. Due to its advantages, LCM has gained attention and competitiveness against other composite manufacturing processes. The resin film infusion (RFI) belongs to the LCM family, but unlike the other variants, such as resin transfer molding (RTM) and vacuum assiste

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Wardana, Raka Sudira, and Khansa Rasyidah. "Evaluation of Aerated Drilling in K-01 Geothermal Well using Guo Ghalambor’s Gas-Liquid Rate Window." PETRO:Jurnal Ilmiah Teknik Perminyakan 9, no. 4 (2020): 190–99. http://dx.doi.org/10.25105/petro.v9i4.8158.

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Common problem in geothermal drilling is loss circulation problem. One of the common methods to cure loss circulation problem is using Lost Circulation Materials (LCM), but in the production zone, using LCM can damage the production zone. Therefore, underbalanced drilling is method that can be used to prevent loss circulation problems in production zone in geothermal well. One of the most common underbalanced drilling methods is aerated drilling or foam drilling. Aerated drilling was used to overcome the loss of circulation problem in production zone in K-01 Geothermal Well. Even though, the a

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Jiang, Jin Hua, Ze Xing Wang, and Nan Liang Chen. "Measurement of Transverse Permeability of Fabric Preforms Using Ultrasound Monitoring Technique in LCM Processes." Advanced Materials Research 311-313 (August 2011): 214–17. http://dx.doi.org/10.4028/www.scientific.net/amr.311-313.214.

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Processes of the Liquid Composite Molding (LCM) are widely used in composites produced by impregnation of a dry preform with liquid resin. The resin flow through the preform is usually described by Darcy’s law and the permeability tensor must be obtained for filling process analysis and characterizing the ability of a porous material to be impregnated by a resin ﬂuid. In generally, resin flow in the thickness direction can be neglected for thin parts, but the resin flow in the transverse direction is important for thicker parts. In this study, the transverse permeability measurement device usi

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Carlone, Pierpaolo, and Gaetano S. Palazzo. "Flow Monitoring and Permeability Measurements in LCM Processes by the Means of a Dielectric Sensor." Key Engineering Materials 504-506 (February 2012): 289–94. http://dx.doi.org/10.4028/www.scientific.net/kem.504-506.289.

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Liquid Composite Molding (LCM) processes, widely used to manufacture thermosetting matrix composite materials, are characterized by the impregnation of a dry fibrous perform, by the means of injection or infusion of the catalyzed resin. The increasing industrial application of LCM processes is due to the demand for high performances materials and constant quality productions, combined with the need to reduce human intervention and costs due manufacturing inefficiency. The opportune planning of LCM processes results, however, very complex, being the process characterized by non-stationary multi

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Philipson, Thomas, Marissa Howard, Kevin Johnson, et al. "Abstract 3768: Optimization of digital pathology through laser capture microdissection with a 405 nm laser." Cancer Research 84, no. 6_Supplement (2024): 3768. http://dx.doi.org/10.1158/1538-7445.am2024-3768.

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Abstract Tumor cellular heterogeneity is a complex problem in cancer molecular diagnostics and personalized therapy. The tumor is a product of the different types and interactions of host and immune cells. Investigators have created a variety of methods to procure separate subpopulations of the tumor microenvironment for individual analysis. One of the most successful methods of this is laser capture microdissection (LCM). This method captures specific subpopulations of cells under direct microscopic visualization. This LCM technology has successfully been used for over 20 years, revealing a v

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Lee, Lu, and Arash Dahi Taleghani. "Simulating Fracture Sealing by Granular LCM Particles in Geothermal Drilling." Energies 13, no. 18 (2020): 4878. http://dx.doi.org/10.3390/en13184878.

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Lost circulation occurs when the returned fluid is less than what is pumped into the well due to loss of fluid to pores or fractures. A lost-circulation event is a common occurrence in a geothermal well. Typical geothermal reservoirs are often under-pressured and have larger fracture apertures. A severe lost-circulation event is costly and may lead to stuck pipe, well instability, and well abandonment. One typical treatment is adding lost-circulation materials (LCMs) to seal fractures. Conventional LCMs fail to properly seal fractures because their mechanical limit is exceeded at elevated temp

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Anwar, Fauzia Fadhila, and Raka Sudira Wardana. "Designing Liquid-Gas Rate Window of Aerated Drilling Using Guo-Ghalambor Method." Jurnal Migasian 4, no. 2 (2020): 1–10. http://dx.doi.org/10.36601/jurnal-migasian.v4i2.135.

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Loss circulation is a common problem in geothermal drilling due to naturally fractured formation and depleted reservoir pressure. This problem might lead to another problem such as a stuck pipe. In some cases, LCM is not effective in curing loss in a naturally fractured formation and cannot be used to cure loss circulation in the production zone. One of the methods that can be used to prevent loss circulation and also preventing reservoir damage in geothermal drilling is underbalanced drilling or aerated drilling. In an underbalanced or aerated drilling operation, the ratio of air injection ra

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Johann, Donald Joseph, Ikjae Jae Shin, Michael Tangrea, and Michael Emmert-Buck. "Advancing drug development by leveraging microdissection for proteogenomic analysis of histological sections." Journal of Clinical Oncology 42, no. 16_suppl (2024): e14660-e14660. http://dx.doi.org/10.1200/jco.2024.42.16_suppl.e14660.

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e14660 Background: Combining laser capture microdissection (LCM) with proteogenomics in cancer research offers a targeted way to way to explore the intricate interactions between the tumor microenvironment and tumor cells proper. For immuno-oncology (IO) research, this is especially important, since improvements in the predictability of patient response to IO-based drugs is greatly needed. An improved understanding of the spatial relationships involving tumor cells, stromal cells, blood supply and immune cell interactions may help to inform drug development and improve the indicators of succes

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Bărar, Andrada A., Ioana E. Pralea, Ioana Berindan-Neagoe, et al. "Proteomic patterns in glomerular research, a laser capture microdissection and liquid chromatography-tandem mass spectrometry approach." Revista Romana de Medicina de Laborator 31, no. 4 (2023): 263–74. http://dx.doi.org/10.2478/rrlm-2023-0029.

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Abstract Introduction: Molecular techniques have the potential to shed light on glomerular diseases that conventional renal pathology may be unable to reveal. The aim of this study was to investigate whether proteomic patterns of glomeruli obtained from kidney biopsies can differentiate between minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS) and control groups (CTR). Methods: 18 formalin-fixed, paraffin-embedded (FFPE) renal biopsies comprising three groups of samples (CTR=3, MCD=6, FSGS=9) were subjected to label-free quantitative mass spectrometry. Glomeruli were exci

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Alotaibi, Hatim, Chamil Abeykoon, Constantinos Soutis, and Masoud Jabbari. "A Numerical Thermo-Chemo-Flow Analysis of Thermoset Resin Impregnation in LCM Processes." Polymers 15, no. 6 (2023): 1572. http://dx.doi.org/10.3390/polym15061572.

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This paper presents a numerical framework for modelling and simulating convection–diffusion–reaction flows in liquid composite moulding (LCM). The model is developed in ANSYS Fluent with customised user-defined-functions (UDFs), user-defined-scalar (UDS), and user-defined memory (UDM) codes to incorporate the cure kinetics and rheological characteristics of thermoset resin impregnation. The simulations were performed adopting volume-of-fluid (VOF)—a multiphase flow solution—based on finite volume method (FVM). The developed numerical approach solves Darcy’s law, heat transfer, and chemical rea

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Ngaosi, Niphaphon, Ketsarin Seebunrueng, and Supalax Srijaranai. "In-syringe reversed dispersive liquid–liquid microextraction coupled to high performance liquid chromatography for the determination of sulfonylurea herbicide residues in cereal samples." Analytical Methods 8, no. 21 (2016): 4254–62. http://dx.doi.org/10.1039/c5ay03380b.

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Yan, Shi Lin, Hang Lu, Hua Tan, and Zhong Qi Qiu. "Microscopic Analysis of Flow and Prediction of Effective Permeability for Dual-Scale Porous Fiber Fabrics." Advanced Materials Research 97-101 (March 2010): 1776–81. http://dx.doi.org/10.4028/www.scientific.net/amr.97-101.1776.

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In this paper, the permeability of fiber fabric used in liquid composite molding (LCM) is predicted by the method of numerical simulation. The three-dimensional finite element model of unit cell representing the periodic micro-structure of a plaid is established. In the process of numerical simulation, each fiber bundle in unit cell is treated as a porous medium. Stokes equation and Darcy's law are employed to model the saturated flow between the fiber bundles and the saturated flow in the fiber bundle, respectively. Steady state flow of the finite element model of unit cell is simulated. The

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Wiggert, D. C., F. J. Hatfield, and S. Stuckenbruck. "Analysis of Liquid and Structural Transients in Piping by the Method of Characteristics." Journal of Fluids Engineering 109, no. 2 (1987): 161–65. http://dx.doi.org/10.1115/1.3242638.

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Since liquid-filled piping systems are composed of slender elements, their transient behavior can be described as one-dimensional wave phenomena. Seven wave components are identified: coupled axial compression of liquid and pipe material; coupled transverse shear and bending of the pipe elements in two principal directions; and torsion of the pipe wall. Utilizing the method of characteristics, the combined system of difference equations for pipe elements and the pipe junction boundary conditions comprise a general mathematical tool for predicting the liquid pressure and pipe stress responses t

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Srinivasarao, Pakalapati, Swamy Rumalla Chidananda, Babu Korupolu Raghu, and Kaliyaperumal Muralidharan. "Development and validation of bio analytical liquid chromatography and mass spectrometry method for quantification of upadacitinib in human plasma." Research Journal of Chemistry and Environment 25, no. 8 (2022): 7–16. http://dx.doi.org/10.25303/258rjce0716.

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In the present investigation, a simple, rapid and sensitive liquid chromatography and mass spectrometry (LC/MS) method was developed for quantification of Upadacitinib (UCB) in spiked human plasma. The drug UCB was extracted by liquid –liquid extraction using diethyl ether and chloroform in the ratio of 75:25 (v/v). The drug Leflunomide (LFM) was used as an internal standard. The extracted drug mixture was followed by the liquid chromatography mass spectrometry (LC/MS) analysis and electrospray ionization interface. The chromatographic separation of UCB was carried out on Phenomenex Luna C18 c

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Shin, Ik Jae, Michael Tangrea, Michael R. Emmert-Buck, and Donald J. Johann. "Abstract 730: Leveraging microdissection for proteogenomic analysis of histological sections to advance drug development." Cancer Research 84, no. 6_Supplement (2024): 730. http://dx.doi.org/10.1158/1538-7445.am2024-730.

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Abstract Background: Combining proteogenomics with laser capture microdissection (LCM) in cancer research offers a targeted way to explore the intricate interactions between tumor cells and the tumor microenvironment. This is especially important for immuno-oncology (IO) research where improvements in the predictability of patient response to IO-based drugs is sorely needed. An improved understanding of the spatial relationships involving tumor cells proper, stromal cells, blood supply and immune cell interactions may help to inform drug development and improve the indicators of success for IO

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