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Journal articles on the topic 'Long-term memory in adolescence'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 January 2023

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1

Skalaban, Lena J., Alexandra O. Cohen, May I. Conley, et al. "Adolescent-specific memory effects: evidence from working memory, immediate and long-term recognition memory performance in 8–30 yr olds." Learning & Memory 29, no. 8 (2022): 223–33. http://dx.doi.org/10.1101/lm.053539.121.

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Working memory and recognition memory develop across adolescence, but the relationship between them is not fully understood. We investigated associations between n-back task performance and subsequent recognition memory in a community sample (8–30 yr, n = 150) using tasks from the Adolescent Brain Cognitive Development Study (ABCD Study) to cross-sectionally assess memory in an age range that will be sampled longitudinally. We added a 24-h delay condition to assess long-term recognition. Overall working memory, immediate and long-term recognition performance peaked in adolescence. Age effects

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Potkin, Katya Trudeau, and William E. Bunney. "Sleep Improves Memory: The Effect of Sleep on Long Term Memory in Early Adolescence." PLoS ONE 7, no. 8 (2012): e42191. http://dx.doi.org/10.1371/journal.pone.0042191.

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Wade, Mark, Nathan A. Fox, Charles H. Zeanah, and Charles A. Nelson. "Long-term effects of institutional rearing, foster care, and brain activity on memory and executive functioning." Proceedings of the National Academy of Sciences 116, no. 5 (2019): 1808–13. http://dx.doi.org/10.1073/pnas.1809145116.

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Children experiencing psychosocial deprivation as a result of early institutional rearing demonstrate many difficulties with memory and executive functioning (EF). To date, there is scant evidence that foster care placement remediates these difficulties during childhood. The current study examined longitudinal trajectories of memory and EF from childhood to adolescence in the Bucharest Early Intervention Project, a randomized controlled trial of foster care for institutionally reared children. We demonstrate that both ever- and never-institutionalized children show age-related improvements on

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Green, Matthew R., and Cheryl M. McCormick. "Effects of social instability stress in adolescence on long-term, not short-term, spatial memory performance." Behavioural Brain Research 256 (November 2013): 165–71. http://dx.doi.org/10.1016/j.bbr.2013.08.011.

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Hunter, Colton L., and Grant S. Shields. "Mediators of the associations between family income during adolescence and adult long-term memory and working memory." Cognitive Development 61 (January 2022): 101140. http://dx.doi.org/10.1016/j.cogdev.2021.101140.

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de Bruijn, Marienke A. A. M., Femke K. Aarsen, Marielle P. van Oosterhout, et al. "Long-term neuropsychological outcome following pediatric anti-NMDAR encephalitis." Neurology 90, no. 22 (2018): e1997-e2005. http://dx.doi.org/10.1212/wnl.0000000000005605.

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ObjectiveTo provide detailed long-term outcome data of children and adolescents following pediatric anti-N-methyl-d-aspartate receptor (anti-NMDAR) encephalitis, to identify neuropsychological impairments, and to evaluate the influence of these factors on quality of life (QoL).MethodsAll Dutch children diagnosed with anti-NMDAR encephalitis were identified. Patients currently aged 4 years or older were included in the follow-up study, consisting of a visit to our clinic for a detailed interview and a standardized neuropsychological assessment. The following domains were included: attention, me

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Yin, Y., H. Li, J. Wang, Y. Kong, J. Chang, and G. Chu. "Implication of microglia in ketamine-induced long-term cognitive impairment in murine pups." Human & Experimental Toxicology 41 (January 2022): 096032712211287. http://dx.doi.org/10.1177/09603271221128739.

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Background Ketamine, a non-competitive N-methyl-D-aspartate receptor (NMDAR) antagonist, is widely applicable to anesthesia, analgesia, and sedation. However, the function and mechanisms of ketamine in the long-term learning and memory function of neonatal mice are unclear. Objective The present study aims to investigate whether long-term learning and memory function will be affected by multiple ketamine exposures in the early development period. Methods The mRNA and protein levels were measured by RT-qPCR and western blot, respectively. The Morris Water Maze test was performed to assess spati

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Yurgelun-Todd, Deborah A., William D. S. Killgore, and Christina B. Cintron. "Cognitive Correlates of Medial Temporal Lobe Development across Adolescence: A Magnetic Resonance Imaging Study." Perceptual and Motor Skills 96, no. 1 (2003): 3–17. http://dx.doi.org/10.2466/pms.2003.96.1.3.

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Adolescent development involves progressive changes in brain structure and cognitive function, but relatively few studies have documented the cognitive correlates of differences in structural brain volumes in this age group. We examined the relations among age, cognitive processing, and mesial temporal lobe volume in 37 children and adolescents. Participants completed a brief cognitive assessment battery and underwent volumetric structural magnetic resonance imaging. For the sample as a whole, amygdala volume correlated positively with age, and larger volumes of both the left and right amygdal

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Rico-Barrio, Irantzu, Sara Peñasco, Leire Lekunberri, et al. "Environmental Enrichment Rescues Endocannabinoid-Dependent Synaptic Plasticity Lost in Young Adult Male Mice after Ethanol Exposure during Adolescence." Biomedicines 9, no. 7 (2021): 825. http://dx.doi.org/10.3390/biomedicines9070825.

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Binge drinking (BD) is a serious health concern in adolescents as high ethanol (EtOH) consumption can have cognitive sequelae later in life. Remarkably, an enriched environment (EE) in adulthood significantly recovers memory in mice after adolescent BD, and the endocannabinoid, 2-arachydonoyl-glycerol (2-AG), rescues synaptic plasticity and memory impaired in adult rodents upon adolescent EtOH intake. However, the mechanisms by which EE improves memory are unknown. We investigated this in adolescent male C57BL/6J mice exposed to a drinking in the dark (DID) procedure four days per week for a d

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Ryan, Christopher M. "Age‐related improvement in short‐term memory efficiency during adolescence." Developmental Neuropsychology 6, no. 3 (1990): 193–205. http://dx.doi.org/10.1080/87565649009540460.

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Grochecki, Pawel, Irena Smaga, Malgorzata Lopatynska-Mazurek, et al. "Effects of Mephedrone and Amphetamine Exposure during Adolescence on Spatial Memory in Adulthood: Behavioral and Neurochemical Analysis." International Journal of Molecular Sciences 22, no. 2 (2021): 589. http://dx.doi.org/10.3390/ijms22020589.

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A synthetic cathinone, mephedrone is widely abused by adolescents and young adults. Despite its widespread use, little is known regarding its long-term effects on cognitive function. Therefore, we assessed, for the first time, whether (A) repeated mephedrone (30 mg/kg, i.p., 10 days, once a day) exposure during adolescence (PND 40) induces deleterious effects on spatial memory and reversal learning (Barnes maze task) in adult (PND 71–84) rats and whether (B) these effects were comparable to amphetamine (2.5 mg/kg, i.p.). Furthermore, the influence of these drugs on MMP-9, NMDA receptor subunit

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Grochecki, Pawel, Irena Smaga, Malgorzata Lopatynska-Mazurek, et al. "Effects of Mephedrone and Amphetamine Exposure during Adolescence on Spatial Memory in Adulthood: Behavioral and Neurochemical Analysis." International Journal of Molecular Sciences 22, no. 2 (2021): 589. http://dx.doi.org/10.3390/ijms22020589.

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A synthetic cathinone, mephedrone is widely abused by adolescents and young adults. Despite its widespread use, little is known regarding its long-term effects on cognitive function. Therefore, we assessed, for the first time, whether (A) repeated mephedrone (30 mg/kg, i.p., 10 days, once a day) exposure during adolescence (PND 40) induces deleterious effects on spatial memory and reversal learning (Barnes maze task) in adult (PND 71–84) rats and whether (B) these effects were comparable to amphetamine (2.5 mg/kg, i.p.). Furthermore, the influence of these drugs on MMP-9, NMDA receptor subunit

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Skerry, Ciaran M., and Bernard P. Mahon. "A Live, AttenuatedBordetella pertussisVaccine Provides Long-Term Protection against Virulent Challenge in a Murine Model." Clinical and Vaccine Immunology 18, no. 2 (2010): 187–93. http://dx.doi.org/10.1128/cvi.00371-10.

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ABSTRACTDespite successful mass vaccination programs, whooping cough remains a significant cause of neonatal mortality. Immunity induced by current vaccines wanes in adolescence, requiring additional immunizations to prevent resurgence. There is a need for a new generation of vaccines capable of conferring long-lasting immunity from birth. Recently, a live, attenuated whooping cough vaccine, BPZE1, has been developed. Here, an established murine immunization model was used to examine the induction and longevity of immunological memory. In this predictive model, BPZE1 conferred a level of prote

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Nakamura, Emi, Hiroyuki Kinoshita, Guo-Gang Feng, et al. "Sevoflurane Inhalation Accelerates the Long-Term Memory Consolidation via Small GTPase Overexpression in the Hippocampus of Mice in Adolescence." PLOS ONE 11, no. 9 (2016): e0163151. http://dx.doi.org/10.1371/journal.pone.0163151.

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Rovio, Suvi P., Jukka Pihlman, Katja Pahkala, et al. "Childhood Exposure to Parental Smoking and Midlife Cognitive Function." American Journal of Epidemiology 189, no. 11 (2020): 1280–91. http://dx.doi.org/10.1093/aje/kwaa052.

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Abstract We studied whether exposure to parental smoking in childhood/adolescence is associated with midlife cognitive function, leveraging data from the Cardiovascular Risk in Young Finns Study. A population-based cohort of 3,596 children/adolescents aged 3–18 years was followed between 1980 and 2011. In 2011, cognitive testing was performed on 2,026 participants aged 34–49 years using computerized testing. Measures of secondhand smoke exposure in childhood/adolescence consisted of parental self-reports of smoking and participants’ serum cotinine levels. Participants were classified into 3 ex

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Bilecki, Wiktor, Agnieszka Wawrzczak-Bargieła, Iwona Majcher-Maślanka, Magdalena Chmelova, and Marzena Maćkowiak. "Inhibition of BET Proteins during Adolescence Affects Prefrontal Cortical Development: Relevance to Schizophrenia." International Journal of Molecular Sciences 22, no. 16 (2021): 8710. http://dx.doi.org/10.3390/ijms22168710.

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Background: The present study investigated the role of proteins from the bromodomain and extra-terminal (BET) family in schizophrenia-like abnormalities in a neurodevelopmental model of schizophrenia induced by prenatal methylazoxymethanol (MAM) administration (MAM-E17). Methods: An inhibitor of BET proteins, JQ1, was administered during adolescence on postnatal days (P) 23–P29, and behavioural responses (sensorimotor gating, recognition memory) and prefrontal cortical (mPFC) function (long-term potentiation (LTP), molecular and proteomic analyses) studies were performed in adult males and fem

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Peñasco, Sara, Irantzu Rico-Barrio, Nagore Puente, et al. "Intermittent ethanol exposure during adolescence impairs cannabinoid type 1 receptor-dependent long-term depression and recognition memory in adult mice." Neuropsychopharmacology 45, no. 2 (2019): 309–18. http://dx.doi.org/10.1038/s41386-019-0530-5.

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van den Buuse, Maarten, Laetitia Buret, and Rachel Hill. "Involvement of brain-derived neurotrophic factor (BDNF) in the long-term memory effects of glucocorticoid stimulation during adolescence/young adulthood." Behavioural Brain Research 377 (January 2020): 112223. http://dx.doi.org/10.1016/j.bbr.2019.112223.

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Sjöwall, Douglas, Lisa B. Thorell, Mirko Mandic, and Maria Westerståhl. "No effects of a long-term physical activity intervention on executive functioning among adolescents." SAGE Open Medicine 7 (January 2019): 205031211988073. http://dx.doi.org/10.1177/2050312119880734.

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Objectives: We investigated whether a school-based physical activity intervention would lead to improvements in working memory, inhibition and cognitive flexibility in adolescents aged 13–15 years. Methods: The adolescents at the active school ( n = 108) participated in an intervention that included increased physical activity for 20 min/day, focused on aerobic activity with low cognitive demands for an entire school year. The adolescents at the control school ( n = 59) received no extra physical activity. At the beginning (baseline) and end (follow-up) of the school year, the participants per

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Mancini, Giulia Federica, Enrico Marchetta, Irene Pignani, Viviana Trezza, and Patrizia Campolongo. "Social Defeat Stress during Early Adolescence Confers Resilience against a Single Episode of Prolonged Stress in Adult Rats." Cells 10, no. 2 (2021): 360. http://dx.doi.org/10.3390/cells10020360.

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Early-life adverse experiences (first hit) lead to coping strategies that may confer resilience or vulnerability to later experienced stressful events (second hit) and the subsequent development of stress-related psychopathologies. Here, we investigated whether exposure to two stressors at different stages in life has long-term effects on emotional and cognitive capabilities, and whether the interaction between the two stressors influences stress resilience. Male rats were subjected to social defeat stress (SDS, first hit) in adolescence and to a single episode of prolonged stress (SPS, second

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Froudist-Walsh, Sean, Diana López-Barroso, María José Torres-Prioris, Paula L. Croxson, and Marcelo L. Berthier. "Plasticity in the Working Memory System: Life Span Changes and Response to Injury." Neuroscientist 24, no. 3 (2017): 261–76. http://dx.doi.org/10.1177/1073858417717210.

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Working memory acts as a key bridge between perception, long-term memory, and action. The brain regions, connections, and neurotransmitters that underlie working memory undergo dramatic plastic changes during the life span, and in response to injury. Early life reliance on deep gray matter structures fades during adolescence as increasing reliance on prefrontal and parietal cortex accompanies the development of executive aspects of working memory. The rise and fall of working memory capacity and executive functions parallels the development and loss of neurotransmitter function in frontal cort

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Windjatika, Hafshah Haudli, and Warih Maharani. "Depression Detection on Social Media Twitter Using Long Short-Term Memory." JURNAL MEDIA INFORMATIKA BUDIDARMA 6, no. 4 (2022): 1835. http://dx.doi.org/10.30865/mib.v6i4.4457.

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Mental health problems in the world, especially in Indonesia are still significant. According to the Ministry of Health of the Republic of Indonesia stated that depression is experienced by adolescents from the age of 15 to 24 years. The depression experienced by a person is sometimes not realized by the sufferer, so social media becomes an intermediary to express feelings in text form. From the available data, this case pushes the research to detect depression disorder. Detecting depression performs to know the Twitter user who experiences depression. Data used from 159 Twitter users for ever

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Queiroz, Letícia Yoshitome, Igor Gonçalves de Oliveira, Sabrina de Carvalho Cartágenes, et al. "Repeated Cycles of Binge-Like Ethanol Exposure Induces Neurobehavioral Changes During Short- and Long-Term Withdrawal in Adolescent Female Rats." Oxidative Medicine and Cellular Longevity 2022 (October 25, 2022): 1–11. http://dx.doi.org/10.1155/2022/7207755.

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Alcohol consumption is spread worldwide and can lead to an abuse profile associated with severe health problems. Adolescents are more susceptible to addiction and usually consume ethanol in a binge drinking pattern. This form of consumption can lead to cognitive and emotional disorders, however scarce studies have focused on long-term hazardous effects following withdrawal periods after binge drinking in adolescents. Thus, the present study aims at investigating whether behavioral and cognitive changes persist until mid and late adulthood. Female Wistar rats (9-10 animals/group) received intra

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Pugin, Fiona, Andreas J. Metz, Madlaina Stauffer, Martin Wolf, Oskar G. Jenni, and Reto Huber. "Working memory training shows immediate and long-term effects on cognitive performance in children and adolescents." F1000Research 3 (April 2, 2014): 82. http://dx.doi.org/10.12688/f1000research.3665.1.

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Working memory is important for mental reasoning and learning processes. Several studies in adults and school-age children have shown performance improvement in cognitive tests after working memory training. Our aim was to examine not only immediate but also long-term effects of intensive working memory training on cognitive performance tests in children and adolescents. Fourteen healthy male subjects between 10 and 16 years trained a visuospatial n-back task over 3 weeks (30 min daily), while 15 individuals of the same age range served as a passive control group. Significant differences in im

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Richards, Marcus, Rebecca Hardy, and Michael EJ Wadsworth. "Long-term effects of breast-feeding in a national birth cohort: educational attainment and midlife cognitive function." Public Health Nutrition 5, no. 5 (2002): 631–35. http://dx.doi.org/10.1079/phn2002338.

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Abstract:Objective:A recent meta-analysis showed that breast-feeding confers a 3.2 point increment in cognitive function through adolescence. Little is known, however, about possible longer-term effects of breast-feeding. We investigated the effect of breast-feeding on educational attainment, and on a range of cognitive skills in midlife, in the British 1946 birth cohort.Objective:Design: Regression analyses were used to test the association between breast-feeding, likelihood of obtaining advanced educational qualifications by age 26 years, and three cognitive test scores at age 53 years: i.e.

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Schweren, Lizanne, Pieter Hoekstra, Marloes van Lieshout, et al. "Long-term effects of stimulant treatment on ADHD symptoms, social–emotional functioning, and cognition." Psychological Medicine 49, no. 2 (2018): 217–23. http://dx.doi.org/10.1017/s0033291718000545.

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AbstractBackgroundMethodological and ethical constraints have hampered studies into long-term lasting outcomes of stimulant treatment in individuals with attention-deficit/hyperactivity disorder (ADHD). Lasting effects may be beneficial (i.e. improved functioning even when treatment is temporarily ceased) or detrimental (i.e. worse functioning while off medication), but both hypotheses currently lack empirical support. Here we investigate whether stimulant treatment history predicts long-term development of ADHD symptoms, social–emotional functioning or cognition, measured after medication was

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Chieffo, Daniela, Gianpiero Tamburrini, Luca Massimi, et al. "Long-term neuropsychological development in single-suture craniosynostosis treated early." Journal of Neurosurgery: Pediatrics 5, no. 3 (2010): 232–37. http://dx.doi.org/10.3171/2009.10.peds09231.

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Object The authors evaluated the results of complete cognitive function examinations in a series of 65 adolescents who had undergone surgery for sagittal or unicoronal craniosynostosis when they were younger than 1 year old. Methods Each of the 65 study participants was evaluated individually. The neuropsychological assessment, consisting of a battery of tests tailored to the patient's age, cognitive level, and level of cooperation, was conducted in 2 separate sessions on the same day. The main outcome measures included fine motor skills, language, visual motor spatial and visual perceptual sk

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Schalbetter, Sina-Maria, Kara Dawson, Flavia Müller, et al. "T179. WHEN TOO LITTLE IS TOO MUCH: TEMPORARY PREFRONTAL MICROGLIA DEFICIENCY DURING ADOLESCENCE IMPAIRS ADULT BRAIN FUNCTIONS." Schizophrenia Bulletin 46, Supplement_1 (2020): S299—S300. http://dx.doi.org/10.1093/schbul/sbaa029.739.

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Abstract Background Aberrant activity of microglia, the primary innate immune cells of the brain parenchyma, may play a role in the etiology and pathophysiology of schizophrenia and related disorders. While current immunopsychiatric research indicates that microglial hyperactivity may contribute to psychotic illness in some cases, the diametrical opposite (i.e. microglial hypoactivity) may be pathologically and therapeutically relevant for others. The latter hypothesis, however, remains largely unexplored and thus warrants investigation. Methods We aimed at developing a model system in mice, i

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Geier, Charles F., Krista Garver, Robert Terwilliger, and Beatriz Luna. "Development of Working Memory Maintenance." Journal of Neurophysiology 101, no. 1 (2009): 84–99. http://dx.doi.org/10.1152/jn.90562.2008.

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The neural circuitry supporting mature visual spatial working memory (VSWM) has been well delineated in nonhuman primates and in human adults. However, we still have limited understanding about developmental change through adolescence in this network. We present results from a fast event-related functional MRI (fMRI) study aimed at characterizing developmental changes in brain mechanisms supporting VSWM across different delay periods. Forty-three healthy subjects (17 adults, 18–30 yr; 13 adolescents, 13–17 yr; 13 children, 8–12 yr) were scanned as they performed an oculomotor delayed response

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Evans, Danielle, Darya Gaysina, and Andy P. Field. "Internalizing symptoms and working memory as predictors of mathematical attainment trajectories across the primary–secondary education transition." Royal Society Open Science 7, no. 5 (2020): 191433. http://dx.doi.org/10.1098/rsos.191433.

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The transition from primary to secondary education is a critical period in early adolescence which is related to increased anxiety and stress, increased prevalence of mental health issues, and decreased maths performance, suggesting it is an important period to investigate maths attainment. Previous research has focused on anxiety and working memory as predictors of maths, without investigating any long-term effects around the education transition. This study examined working memory and internalizing symptoms as predictors of children's maths attainment trajectories (age 7–16) across the trans

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Chen, Zekun, Huanhuan Yang, Dongqing Wang, et al. "Effect of Oral Iron Supplementation on Cognitive Function among Children and Adolescents in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis." Nutrients 14, no. 24 (2022): 5332. http://dx.doi.org/10.3390/nu14245332.

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Background: There is abundant evidence showing that iron deficiency is closely linked with delayed brain development, worse school performance, and behavioral abnormalities. However, evidence on the impact of iron supplementation among children and adolescents in low- and middle-income countries (LMICs) has been inconsistent. This study aims to examine the effect of oral iron supplementation on cognitive function among children and adolescents in LMICs. Methods: A systematic review and meta-analysis was conducted to examine the impact of iron supplementation on cognitive function (including in

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Siegel, Linda S. "Working Memory and Reading: A Life-span Perspective." International Journal of Behavioral Development 17, no. 1 (1994): 109–24. http://dx.doi.org/10.1177/016502549401700107.

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The relationships among working memory, memory span, and reading skills were studied in 1266 individuals, aged 6-49. They were administered tests of word recognition, pseudoword decoding, reading comprehension, a working memory (listening span) task that required the simultaneous processing of syntax and the recall of linguistic information, and a short-term memory task that required the recall of rhyming or nonrhyming letters presented visually. The results indicated that there is a gradual growth in the development of working memory skills from ages 6 to 19 and a gradual decline after adoles

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Fodor, Miklós, and Gyula Sófi. "Az ifjúsági drogkarrier veszélyei." Orvosi Hetilap 156, no. 46 (2015): 1843–46. http://dx.doi.org/10.1556/650.2015.30284.

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It is determinative, when a teenager meets drugs first. Research have shown that 70% of later dependents try the drugs during the five-year periods of adolescence. Youngsters are tend to try out new experinces; they are high risk-takings, seek for novelties and are sensitive for the pressure of community. However, the juvenile central nervous system reacts differently if meets drugs, than it is happens in an older age. Damage could occur on critical regions of the brain. Addictive drugs may give rise changes in the multiplex system of memory, that could maintain the addiction long term. Drug u

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Abe, Yushi, Daigo Ochiai, Yu Sato, et al. "Prophylactic Therapy with Human Amniotic Fluid Stem Cells Improves Long-Term Cognitive Impairment in Rat Neonatal Sepsis Survivors." International Journal of Molecular Sciences 21, no. 24 (2020): 9590. http://dx.doi.org/10.3390/ijms21249590.

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A systemic inflammatory response induces multiple organ dysfunction and results in poor long-term neurological outcomes in neonatal sepsis. However, there is no effective therapy for treating or preventing neonatal sepsis besides antibiotics and supportive care. Therefore, a novel strategy to improve neonatal sepsis-related morbidity and mortality is desirable. Recently, we reported that prophylactic therapy with human amniotic stem cells (hAFSCs) improved survival in a rat model of lipopolysaccharide (LPS)-induced neonatal sepsis through immunomodulation. Besides improving the mortality, incr

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Raymond, Julie, Alexandre Morin, Marilou Poitras, and Hélène Plamondon. "Short-Term Fish Oil Supplementation during Adolescence Supports Sex-Specific Impact on Adulthood Visuospatial Memory and Cognitive Flexibility." Nutrients 14, no. 17 (2022): 3513. http://dx.doi.org/10.3390/nu14173513.

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Numerous studies have supported benefits of omega-3 supplementation using Menhaden fish oil (FO) to promote brain maturation and plasticity during critical developmental periods. The goal of this study was to determine sex-specific immediate and delayed impact of adolescent omega-3 supplementation on visuospatial memory and cognitive flexibility. Sixty-four Wistar rats (n = 32 males and females) received daily FO or soybean oil (CSO) supplementation via oral gavage (0.3 mL/100 g body weight) from postnatal day 28–47. The Barnes Maze Test (BMT) was used to measure visuospatial memory and revers

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Thompson, Deanne K., Joseph Y. M. Yang, Jian Chen, et al. "Brain White Matter Development Over the First 13 Years in Very Preterm and Typically Developing Children Based on the T₁-w/T₂-w Ratio." Neurology 98, no. 9 (2021): e924-e937. http://dx.doi.org/10.1212/wnl.0000000000013250.

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Background and ObjectivesTo investigate brain regional white matter development in full-term (FT) and very preterm (VP) children at term equivalent and 7 and 13 years of age based on the ratio of T1- and T2-weighted MRI (T1-w/T2-w), including (1) whether longitudinal changes differ between birth groups or sexes, (2) associations with perinatal risk factors in VP children, and (3) relationships with neurodevelopmental outcomes at 13 years.MethodsProspective longitudinal cohort study of VP (born <30 weeks' gestation or <1,250 g) and FT infants born between 2001 and 2004 and followed up at

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Baudou, Eloïse, Jérémie Pariente, Patrice Péran, et al. "A prospective behavioral and imaging study exploring the impact on long-term memory of radiotherapy delivered for a brain tumor in childhood and adolescence." Clinical and Translational Radiation Oncology 33 (March 2022): 7–14. http://dx.doi.org/10.1016/j.ctro.2021.10.006.

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Fraello, David, Jill Maller-Kesselman, Betty Vohr, et al. "Consequence of Preterm Birth in Early Adolescence: The Role of Language on Auditory Short-term Memory." Journal of Child Neurology 26, no. 6 (2011): 738–42. http://dx.doi.org/10.1177/0883073810391904.

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Kumar, Parvathi, Pamela Hair, Kenji Cunnion, Neel Krishna, and Thomas Bass. "Classical complement pathway inhibition reduces brain damage in a hypoxic ischemic encephalopathy animal model." PLOS ONE 16, no. 9 (2021): e0257960. http://dx.doi.org/10.1371/journal.pone.0257960.

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Perinatal hypoxic ischemic encephalopathy (HIE) remains a major contributor of infant death and long-term disability worldwide. The role played by the complement system in this ischemia-reperfusion injury remains poorly understood. In order to better understand the role of complement activation and other modifiable mechanisms of injury in HIE, we tested the dual-targeting anti-inflammatory peptide, RLS-0071 in an animal model of HIE. Using the well-established HIE rat pup model we measured the effects of RLS-0071 during the acute stages of the brain injury and on long-term neurocognitive outco

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Macht, Victoria, Natalie Elchert, and Fulton Crews. "Adolescent Alcohol Exposure Produces Protracted Cognitive-Behavioral Impairments in Adult Male and Female Rats." Brain Sciences 10, no. 11 (2020): 785. http://dx.doi.org/10.3390/brainsci10110785.

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Binge drinking is common in adolescence. Rodent studies modeling adolescent binge drinking find persistent effects on the brain’s physiology, including increased expression of neuroimmune genes, impaired neurogenesis, and changes in behavioral flexibility. This study used females and males to investigate the effects of adolescent intermittent ethanol (AIE) on a battery of behaviors assessing spatial navigation using a radial arm water maze, working memory using the Hebb-Williams maze, non-spatial long-term memory using novel object recognition, and dominance using a tube dominance test. Result

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Conti-Ramsden, Gina, and Kevin Durkin. "Phonological short-term memory, language and literacy: developmental relationships in early adolescence in young people with SLI." Journal of Child Psychology and Psychiatry 48, no. 2 (2007): 147–56. http://dx.doi.org/10.1111/j.1469-7610.2006.01703.x.

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Edalati, Hanie, and Marvin D. Krank. "Childhood Maltreatment and Development of Substance Use Disorders." Trauma, Violence, & Abuse 17, no. 5 (2016): 454–67. http://dx.doi.org/10.1177/1524838015584370.

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Exposure to childhood maltreatment (CM) is associated with increased risk for developing substance use disorders (SUDs). CM exerts negative effects on cognitive abilities including intellectual performance, memory, attention, and executive function. Parallel cognitive impairments have been observed in SUDs. Hence, limited studies have examined the mediating effect of cognitive impairments in the relationship between CM and SUDs. In addition, most studies used concurrent self-report assessments in adult populations. Longitudinal studies that investigated the long-term consequences of CM on psyc

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Stefanatou, P., C. S. Karatosidi, E. Kattoulas, N. Stefanis, and N. Smyrnis. "The relationship between premorbid adjustment and cognitive dysfunction in schizophrenia." European Psychiatry 33, S1 (2016): S78—S79. http://dx.doi.org/10.1016/j.eurpsy.2016.01.023.

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IntroductionPremorbid adjustment (PA) is one of the main prognostic indicators of schizophrenia. Both social and cognitive deficits observed during the premorbid period hold a predictive value for the onset of schizophrenia.ObjectivesTo investigate how cognitive functions are related to aspects of PA.AimsTo examine the relationship of each PA domain (academic and social) at each of the three developmental stages (childhood, early adolescence and late adolescence), as well as their course with the cognitive functions in schizophrenia patients.MethodsPA, intellectual quotient (IQ), verbal learni

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POST, ROBERT M., GABRIELE S. LEVERICH, GUOQIANG XING, and SUSAN R. B. WEISS. "Developmental vulnerabilities to the onset and course of bipolar disorder." Development and Psychopathology 13, no. 3 (2001): 581–98. http://dx.doi.org/10.1017/s0954579401003091.

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Different types of psychosocial stressors have long been recognized as potential precipitants of both unipolar and bipolar affective episodes and the causative agents in posttraumatic stress disorder (PTSD). New preclinical data have revealed some of the neurobiological mechanisms that could convey the long-term behavioral and biochemical consequences of early stressors. Depending on the timing, quality, quantity, and degree of repetition, maternal deprivation stress in the neonatal rodent can be associated with lifelong anxiety-like behaviors, increases in stress hormones and peptides, and pr

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Yang, Yingying, Zachary M. Himmelberger, Trent Robinson, Megan Davis, Frances Conners, and Edward Merrill. "Everyday Memory in People with Down Syndrome." Brain Sciences 11, no. 5 (2021): 551. http://dx.doi.org/10.3390/brainsci11050551.

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Although memory functions in people with Down Syndrome (DS) have been studied extensively, how well people with DS remember things about everyday life is not well understood. In the current study, 31 adolescents/young adults with DS and 26 with intellectual disabilities (ID) of mixed etiology (not DS) participated. They completed an everyday memory questionnaire about personal facts and recent events (e.g., school name, breakfast). They also completed a standard laboratory task of verbal long-term memory (LTM) where they recalled a list of unrelated words over trials. Results did not indicate

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Stojanovic, Tamara, David Velarde Gamez, Gabor Jorrid Schuld, et al. "Age-Dependent and Pathway-Specific Bimodal Action of Nicotine on Synaptic Plasticity in the Hippocampus of Mice Lacking the miR-132/212 Genes." Cells 11, no. 2 (2022): 261. http://dx.doi.org/10.3390/cells11020261.

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Nicotine addiction develops predominantly during human adolescence through smoking. Self-administration experiments in rodents verify this biological preponderance to adolescence, suggesting evolutionary-conserved and age-defined mechanisms which influence the susceptibility to nicotine addiction. The hippocampus, a brain region linked to drug-related memory storage, undergoes major morpho-functional restructuring during adolescence and is strongly affected by nicotine stimulation. However, the signaling mechanisms shaping the effects of nicotine in young vs. adult brains remain unclear. Micro

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Krupina, Nataliya A., Sophie D. Shirenova, and Nadezhda N. Khlebnikova. "Prolonged Social Isolation, Started Early in Life, Impairs Cognitive Abilities in Rats Depending on Sex." Brain Sciences 10, no. 11 (2020): 799. http://dx.doi.org/10.3390/brainsci10110799.

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Background: The chronic stress of social isolation is a valid predictor of cognitive pathology. This study aimed to compare the effects of long-term social isolation on female versus male Wistar rats’ learning and memory. We hypothesized that prolonged social isolation stress, which starts early in life, would affect learning in a sex-dependent manner. Methods: Social isolation started at the edge of early to mid-adolescence and lasted 9 months. The rat’s cognitive abilities were assessed by habituation and reactivity to novelty in the open field (OF) test, spatial memory in the Morris water m

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Allgulander, Christer, Borwin Bandelow, Eric Hollander, et al. "WCA Recommendations for the Long-Term Treatment of Generalized Anxiety Disorder." CNS Spectrums 8, S1 (2003): 53–61. http://dx.doi.org/10.1017/s1092852900006945.

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ABSTRACTWhat are the current recommendations for the long-term treatment of generalized anxiety disorder (GAD)? GAD is a common disorder with a lifetime prevalence of 4% to 7% in the general population. GAD is characterized by excessive, uncontrollable worry or anxiety about a number of events or activities that the individual experiences on more days than not over a 6-month period. Onset of GAD symptoms usually occurs during an individual's early twenties; however, high rates of GAD have also been seen in children and adolescents. The clinical course of GAD is often chronic, with 40% of patie

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Castellanos-Ryan, Natalie, Jean-Baptiste Pingault, Sophie Parent, Frank Vitaro, Richard E. Tremblay, and Jean R. Séguin. "Adolescent cannabis use, change in neurocognitive function, and high-school graduation: A longitudinal study from early adolescence to young adulthood." Development and Psychopathology 29, no. 4 (2016): 1253–66. http://dx.doi.org/10.1017/s0954579416001280.

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AbstractThe main objective of this prospective longitudinal study was to investigate bidirectional associations between adolescent cannabis use (CU) and neurocognitive performance in a community sample of 294 young men from ages 13 to 20 years. The results showed that in early adolescence, and prior to initiation to CU, poor short-term and working memory, but high verbal IQ, were associated with earlier age of onset of CU. In turn, age of CU onset and CU frequency across adolescence were associated with (a) specific neurocognitive decline in verbal IQ and executive function tasks tapping trial

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Smith, Nina ZY, Pablo J. Vasquez, Nnenna A. Emelogu, Alexis E. Hayes, Joan Engebretson, and Angela J. Nash. "The Good, the Bad, and Recovery: Adolescents Describe the Advantages and Disadvantages of Alternative Peer Groups." Substance Abuse: Research and Treatment 14 (January 2020): 117822182090935. http://dx.doi.org/10.1177/1178221820909354.

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In 2017, approximately 1.5 million American adolescents had a substance use disorder (SUD). Adolescents with SUD risk hindering their neurological development, which can result in problems with memory and self-regulation, and in turn disrupt their education, relationships, and life opportunities. Treating adolescents with SUD is challenging. Thus, effective models that help adolescents engage in long-term recovery are needed. The Alternative Peer Group (APG) is an adolescent recovery support model that incorporates pro-recovery peers and sober social activities into standard continuing care pr

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