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Journal articles on the topic 'Male wistar rats'

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Published: 2 June 2025

Last updated: 31 July 2025

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1

Trumper, Laura, Guillermina Girardi, and María Mónica Elías. "Acetaminophen nephrotoxicity in male Wistar rats." Archives of Toxicology 66, no. 2 (1992): 107–11. http://dx.doi.org/10.1007/bf02342503.

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2

Adekilekun, TijaniAhmad, MusaAbdus-Semiu Adewale, AbayomiTaiwo Adekemi, and AdeniyiTemidayo Daniel. "Cyanide-induced hyperthyroidism in male Wistar rats." Nigerian Medical Journal 55, no. 3 (2014): 246. http://dx.doi.org/10.4103/0300-1652.132060.

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3

Augustine, BD, U. Farrau, M. Olubiyi, T. Danboyi, FA Dawud, and IA Umar. "Lung Oxidative and Nitrosative Changes in Type II Diabetic Male Wistar Rats Treated." J Med & Bas Sci Res 3, no. 1 (2022): 13–22. https://doi.org/10.5281/zenodo.6342043.

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ASTRACT Background: Sustained hyperglycemia in diabetes has been reported to cause excessive production of reactive oxygen and nitrogen species that mediate oxidative and nitrosative stress in the lungs. Lauric acid was reported to possess antioxidant, anti-inflammatory and insulinotropic properties.  Methodology: This study was designed to investigate the effect of lauric acid on the activity of inducible nitric oxide synthase (iNOS), malondialdehyde (MDA) concentration and activities of antioxidant enzymes superoxide dismutase (SOD) and catalase (CAT) in the lungs of type II diabetic ma

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4

Li, Yan, and Kenneth E. McMartin. "Strain differences in urinary factors that promote calcium oxalate crystal formation in the kidneys of ethylene glycol-treated rats." American Journal of Physiology-Renal Physiology 296, no. 5 (2009): F1080—F1087. http://dx.doi.org/10.1152/ajprenal.90727.2008.

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Ethylene glycol (EG)-induced hyperoxaluria is the most commonly employed experimental regimen as an animal model of calcium oxalate (CaOx) stone formation. The variant sensitivity to CaOx among different rat strains has not been fully explored, although the Wistar rat is known to accumulate more CaOx in kidney tissue after low-dose EG exposure than in the Fischer 344 (F344) rats. Supersaturation of CaOx in tubular fluid contributes to the amount of CaOx crystal formation in the kidney. We hypothesized that the urinary supersaturation of CaOx in Wistar rats is higher than that of F344 rats, the

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5

Gautam, Rohit, Neelu Singh, and Usha Singh. "Hematological Changes Induced By 3G Mobile Phone Radiation in Male Wistar Rats." Journal of Advances and Scholarly Researches in Allied Education 15, no. 5 (2018): 124–27. http://dx.doi.org/10.29070/15/57557.

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6

SUNDAR, S. T. BINO, T. J. HARIKRISHNAN, BHASKARAN RAVI LATHA, et al. "Prevalence of syphaciosis in laboratory rodents with emphasis on species identification, treatment and Th2 cytokine response." Indian Journal of Animal Sciences 88, no. 7 (2018): 765–70. http://dx.doi.org/10.56093/ijans.v88i7.81404.

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Prevalence of syphaciosis (pinworm infection) in laboratory rats and mice, species identification, chemotherapy with ivermectin and its effect on pinworm infection, and Th2 cytokine response was studied. Using perianal tape test examination, the highest rate of pinworm infection was found in male Wistar rats (69.44%) followed by female Wistar rats (62.50%), male Balb C mice (60.60%), female Swiss Albino mice (51.42%), male Swiss Albino mice (33.33%) and female Balb C mice (32.69%). Wistar rats had maximum infection (65.97%) followed by Balb C mice (46.64%) and Swiss albino mice (42.37%). Overa

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7

Nitiprodjo, Abdul Hakim, and Titik Kusumawinakhyu. "Perbedaan Penurunan Suhu Tubuh Tikus Wistar Jantan Dan Betina Yang Mati Akibat Diinduksi Metanol." Herb-Medicine Journal 4, no. 2 (2021): 51. http://dx.doi.org/10.30595/hmj.v4i2.10217.

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Someone who dies will experience a decrease in body temperature from body temperature at the beginning of death, both within normal and abnormal limits to room temperature. Decrease in body temperature according to sex may differ in duration. Coupled with exposure to methanol, it is also possible to influence a decrease in body temperature of the corpse. This study aimed to analyze the differences in body temperature reduction in male and female Wistar rats induced with methanol.This research is an experimental study with a pre and post test control group design approach. The design of this st

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8

Saronee, F., D. Dan-Jumbo, and P. Azosibe. "Aphrodisiac properties of Craterispemum schweinfurthi Leaf Extract in Lead Induced Testicular Toxicity in Male Wistar Rats." Journal of Applied Sciences and Environmental Management 28, no. 5 (2024): 1513–18. http://dx.doi.org/10.4314/jasem.v28i5.23.

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The current study was designed to evaluate the aphrodisiac properties of Craterispemum schweinfurthi leaf extract in lead induced testicular toxicity in male Wistar rats using appropriate standard techniques. Adult male Wistar rats were divided into 7 groups and daily treated with different concentrations of extract and phytosterol only. Compared to group 1 (Control) rats, significantly higher values of mount, intromission, ejaculatory latencies as well as post ejaculatory interval and decreased values of mount, intromission and ejaculatory frequencies were observed amongst group 2 (2.25mg/kg

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9

Malfará, Wilson Roberto, Ana Maria de Souza, and Regina Helena Costa Queiroz. "Ranitidine treatment inducing methemoglobinemia in male Wistar rats." Revista Brasileira de Ciências Farmacêuticas 41, no. 2 (2005): 247–52. http://dx.doi.org/10.1590/s1516-93322005000200013.

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10

Ligha, A. E., B. Bokolo, and B. C. Didia. "Antifertility Potentials of Metronidazole in Male Wistar Rats." Pakistan Journal of Biological Sciences 15, no. 5 (2012): 224–30. http://dx.doi.org/10.3923/pjbs.2012.224.230.

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11

Rašić, D., D. Želježić, V. Micek, et al. "Sterigmatocystin induces oxidative stress in male Wistar rats." Toxicology Letters 295 (October 2018): S199—S200. http://dx.doi.org/10.1016/j.toxlet.2018.06.887.

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12

Fekkes, D., B. Bernard, and S. Cappendijk. "Norharman and alcohol-dependency in male wistar rats." European Neuropsychopharmacology 12 (October 2002): 389–90. http://dx.doi.org/10.1016/s0924-977x(02)80644-7.

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13

Selmanoğlu, Güldeniz, Gökçen Mülayimçelik Özgün, and Elif Karacaoğlu. "Acrolein-mediated neurotoxicity in growing Wistar male rats." Pesticide Biochemistry and Physiology 149 (July 2018): 37–43. http://dx.doi.org/10.1016/j.pestbp.2018.05.006.

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14

FEKKES, D. "Norharman and alcohol-dependency in male Wistar rats." European Neuropsychopharmacology 14, no. 5 (2004): 361–66. http://dx.doi.org/10.1016/j.euroneuro.2003.10.007.

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15

Ernawati, Ernawati, and Theresia Ratnasari Widjaja. "Pemanfaatan Seduhan Daun Ashitaba dengan Simvastatin dalam Menurunkan Kadar LDL Tikus Putih Jantan Strain Wistar." Jurnal Ilmiah Kedokteran Wijaya Kusuma 7, no. 1 (2018): 31. http://dx.doi.org/10.30742/jikw.v7i1.256.

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High levels of blood cholesterol or hypercholesterolemia is an important risk factor for a cardiovascular disease. In order to overcome this problem, giving statins drug such as simvastatin is an intervention that is often applied. Besides using this drug, it can also be accompanied by consuming herbal plants which is Ashitaba leaves (Angelica keiskei). It contains Chalcones which demonstrates anti tumour property and also antioxidant activity that can lower cholesterol levels, especially LDL in the blood. This study aimed to investigate the effect of Ashitaba leaves (Angelica keiskei) steepin

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Y. Parmar, Mihir. "Toxicological Evaluation of Methanolic Extract of Vetiveria Zizanioides Roots in Male and Female." Clinical Research Notes 3, no. 1 (2022): 01–07. http://dx.doi.org/10.31579/2690-8816/044.

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Vetiveria zizanioides roots were used from tradition in the treatment of various types of liver disorder. The objective of present study was to evaluate the oral acute and sub-acute toxicity (28 days) of the methanolic extract of Vetiveria zizanioides roots (MEVZ) in Wistar albino rats of both sexes. In the acute toxicity study, Wistar rats were treated orally with a single dose of 5 g/kg of body weight, and were observed for 14 days. Animals were monitored continuously for the first 4 h, for every 6 h for the next 24 h, upto 14 days. In the sub-acute toxicity study, MEVZ was administered oral

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17

Madla, Christine M., Yujia Qin, Francesca K. H. Gavins, et al. "Sex Differences in Intestinal P-Glycoprotein Expression in Wistar versus Sprague Dawley Rats." Pharmaceutics 14, no. 5 (2022): 1030. http://dx.doi.org/10.3390/pharmaceutics14051030.

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Wistar and Sprague Dawley are the most common strains of rat used in pharmaceutical research and are used interchangeably in pre-clinical drug development. No studies have assessed whether Wistar and Sprague Dawley rats are equivalent in the gastrointestinal factors that influence oral drug absorption, specifically in relation to intestinal transporters. Enzyme-linked immunosorbent assay (ELISA) and liquid chromatography–tandem mass spectrometry (LC-MS/MS) are two reliable methods for quantifying intestinal protein levels with their own distinct advantages and limitations. In this study, P-gly

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18

Grace Olufunmilayo, Isehunwa, Chimezie Joseph, and Oyelade Ruth Oluwakemi. "EFFECTS OF PETROL CONTAMINATED DIET AND WATER ONGLUCOSE, LIVER GLYCOGEN, PLASMA LACTATE AND LIPID PROFILE IN MALE WISTAR RATS." International Journal of Advanced Research 12, no. 03 (2024): 244–54. http://dx.doi.org/10.21474/ijar01/18389.

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Exposure to petrol have been shown to cause detrimental health effects. Literature is sparse on whether exposure to petrol causes metabolic disorders. This study investigated the effects of petrol contaminated diet andwater on blood glucose, liver glycogen, plasma lactate, triglycerides and lipid profile in male Wistar rats. The study was divided into two phases. Phase one study consisted of 15 male Wistar rats divided into three groups (n = 5/group). Groups 1-3 were given distilled water, petrol-contaminated diet (20 mL petrol/200 g rodent chow PCD), and petrol-contaminated water (0.5 mL/kg P

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19

Korobova, V. N., I. I. Bobyntsev, and A. O. Vorvul. "Features of Heart Rate Variability in Male and Female Wistar Rats." Journal Biomed 19, no. 1 (2023): 22–33. http://dx.doi.org/10.33647/2074-5982-19-1-22-33.

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In this study, we investigated the heart rate variability (HRV) of awake male and female Wistar rats using a non-invasive technique of electrocardiosignal recording. We established significant differences in the value of HRV indicators in groups of animals differing in spectral parameters (total power of the spectrum (TP), high-(HF) and low-frequency (LF) components of the spectrum). The following HRV indicators were shown to be highly informative: statistical (SDNN — the standard deviation of the complete array of RR intervals, RMSSD — the square root of the standard deviations of successive

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20

Surati, Surati, Lilik Setyowatiningsih, Qurrotu A’yuni Aulia, Santo Yoseph Didik Widiyanto та EM Sutrisna. "Effect of Bamboo Shoot (Gigantochloa Nigrociliata) Extract on Decreased Blood Pressure and Tnf-Α in Male Wistar Rats (Rattus Norvegicus)". Indonesian Journal of Medicine 8, № 1 (2023): 121–27. https://doi.org/10.26911/theijmed.v8i1.639.

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Background: Hypertension is a non-communicable disease based on increased pathologies such as RAS, inflammation, and oxidative stress. Bamboo shoot extract contains BSP, phenol, and flavonoids that can reduce inflammatory status, oxidative stress, and ACE. The study aims to determine the effect of bamboo shoot extract on decreased blood pressure and TNF-α in male Wistar Rats made hypertensive.Subjects and Method: This study used a True Experimental Design with the Posttest Only Control Group Design. The study was located at the Integrated Biomedical Laboratory of the Faculty of Medicine, Sulta

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Surati, Surati, Lilik Setyowatiningsih, Qurrotu A’yuni Aulia, Santo Yoseph Didik Widiyanto та EM Sutrisna. "Effect of Bamboo Shoot (Gigantochloa Nigrociliata) Extract on Decreased Blood Pressure and Tnf-Α in Male Wistar Rats (Rattus Norvegicus)". Indonesian Journal of Medicine 8, № 1 (2023): 121–27. https://doi.org/10.26911/theijmed.2023.8.1.639.

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Background: Hypertension is a non-communicable disease based on increased pathologies such as RAS, inflammation, and oxidative stress. Bamboo shoot extract contains BSP, phenol, and flavonoids that can reduce inflammatory status, oxidative stress, and ACE. The study aims to determine the effect of bamboo shoot extract on decreased blood pressure and TNF-α in male Wistar Rats made hypertensive.Subjects and Method: This study used a True Experimental Design with the Posttest Only Control Group Design. The study was located at the Integrated Biomedical Laboratory of the Faculty of Medicine, Sulta

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22

Alabi, Quadri K., Rufus O. Akomolafe, Modinat A. Adefisayo, et al. "Kolaviron attenuates diclofenac-induced nephrotoxicity in male Wistar rats." Applied Physiology, Nutrition, and Metabolism 43, no. 9 (2018): 956–68. http://dx.doi.org/10.1139/apnm-2017-0788.

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The beneficial effects of kolaviron, a natural biflavonoid from the seeds of Garcinia kola, have been attributed to its antioxidant and anti-inflammatory activities. This study was designed to investigate the renoprotective effect of kolaviron in rat model of diclofenac (DFC)-induced acute renal failure. Thirty-five male Wistar rats were divided into 7 groups of 5 rats each as follows: a control group that received propylene glycol orally and treatment groups that received DFC, DFC recovery, DFC followed by kolaviron at 3 different doses, and kolaviron only. DFC-treated rats showed sluggishnes

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23

Rosida, Holdin Eka Prilia,. "UJI AKTIVITAS EKSTRAK LABU AIR (Lagenaria siceria) TERHADAP LUKA BAKAR TIKUS JANTAN GALUR WISTAR." JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 2, no. 2 (2021): 57–62. http://dx.doi.org/10.53864/jifakfar.v2i2.29.

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Water pumpkin (Lagenaria siceria) is a useful plant in Indonesian. People used water pumpkin flesh as a drug wound, especially as wound burning. This study was prove the activity of water pumpkin flesh extract as wound burning in male rats Wistar strain. The method in this research used experimental. This study used 25 male rats Wistar strain divided into 5 groups. The positive control group was given bioplacenton, the negative control group was given CMC-Na base gel, the other group was given water pumpkin gel extract at doses 2.5%, 5% and 7.5%. compount of water pumpkin extract are flavonoid

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24

Ewuola, E. O., and P. C. Emerue. "Mitigating dietary aflatoxins in Wistar rat using selected phyto-antioxidant sources." Nigerian Journal of Animal Production 48, no. 2 (2021): 38–52. http://dx.doi.org/10.51791/njap.v48i2.2931.

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This study was conducted to investigate the mitigation of dietary aflatoxin in Wistar rats using extract from selected phyto-antioxidant sources. A total of one hundred and twenty Wistar rats weighing between 180-190g (80 females and 40 males) at six weeks old were allotted to eight treatments with 15 rats per treatment (10 females and 5 males), in a completely randomized design. The treatments were Treatment 1 (Normal diet + no extract and no aflatoxin), Treatment 2 (Aflatoxin contaminated diet + no extract), Treatment 3 (Aflatoxin contaminated diet + 100mg/kg BW Carrot extract), Treatment 4

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Svensson, Annika M., Claes-Göran Östenson, Birgitta Bodin, and Leif Jansson. "Lack of compensatory increase in islet blood flow and islet mass in GK rats following 60% partial pancreatectomy." Journal of Endocrinology 184, no. 2 (2005): 319–27. http://dx.doi.org/10.1677/joe.1.05676.

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The effects of a 60% partial pancreatectomy were studied in hyperglycemic GK (Goto–Kakizaki) rats. Partial pancreatectomy or a sham operation was performed on 12-week-old female Wistar rats, GK rats or hybrids between male GK rats and female Wistar rats. Measurements of pancreatic blood flow and islet blood flow were performed by a microsphere technique 2 weeks after surgery. Glucose tolerance was decreased in hybrid compared with Wistar rats, and in GK rats compared with both hybrid and Wistar rats before surgery. Partial pancreatectomy induced minor changes in glucose tolerance. Wistar rats

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Olateju, Bolade S., Serah F. Ige, Adejumo Ridwanullahi, Olasupo Abiodun Samuel, Abiala Grace Asegunloluwa, and Akande Mary Ibukunoluwa. "Gender Differences in the Effects of Cadmium Exposure on Hematological Parameters in Wistar Rats." Asian Journal of Medicine and Health 22, no. 9 (2024): 65–79. http://dx.doi.org/10.9734/ajmah/2024/v22i91091.

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This study aims to investigate the gender dimorphism in cadmium exposure on hematological parameters in male and female Wistar rats. Twenty Wistar rats (120g-150g) were divided into four groups: male control, male cadmium-treated, female control, and female cadmium-treated. Cadmium chloride (50 mg/kg) was administered orally to the experimental groups for 45 days. Hematological parameters were analyzed using an auto hematological analyzer. Data were statistically evaluated using two-way ANOVA with significance set at p < 0.05. Cadmium exposure significantly increased white blood cell (WBC)

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Akintunde, O. G., E. S. Ajibola, S. A. V. Abakpa, B. O. Oluwo, and J. O. Olukunle. "Cardioprotective effects of Citrullus lanatus rinds in male wistar rats." Nigerian Journal of Animal Production 44, no. 1 (2020): 123–29. http://dx.doi.org/10.51791/njap.v44i1.448.

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Water melon, citrullus lanatus is a common edible fruit belongs to the family of cucumber (Cucurbitacea). The outer part of citrullus lanatus known as the rind is always discarded. This study investigated the effects of ethanol extract of citrullus lanatus rinds orally administered on some liver function enzymes, kidney function markers, cardiac risk ratio, and the atherogenic coefficient indices in male wistar rats. Twenty-five male Wistar albino rats were randomly distributed into five groups (I, II, III, IV and V) of five rats each received 0mg/kg, 100 mg/kg, 200mg/kg, 400mg/kg and 800mg/kg

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Akpotu, J. O., S. J. Oniye, S. A. Abdullahi, and B. T. Magaji. "Haematological and hepatho-renal effect of cashew nut oil on male Wistar rats." Nigerian Journal of Basic and Applied Sciences 30, no. 1 (2022): 55–61. http://dx.doi.org/10.4314/njbas.v30i1.8.

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The aim of this study was to evaluate the biosafety of Anacardium occidentale (cashew) nut oil using male Wistar rats as model. Cashew nut oil was extracted from cashew nuts with the aid of a Soxhlet apparatus using n-hexane as solvent. Twelve male Wistar rats were randomly assigned to four groups labeled I, II, III and IV (3 rats per group). Group I served as the control group and were administered distilled water. Group II received 1.53 mL/kg of the nut oil; group III received 4 mL/kg of the nut oil while group IV received 8.13 mL/kg of the nut oil. The administrations were via the oral rout

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29

F, Saronee, Amadi J, and Azosibe P. "Effects of the Hydromethanol Leaf Extract of Craterispermum schweinfurthi on Sperm Characteristics and Haematological Indices in Male Wistar Rats." Cross Current International Journal of Medical and Biosciences 6, no. 01 (2024): 21–25. http://dx.doi.org/10.36344/ccijmb.2024.v06i01.005.

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Sexual and haematological abnormalities are on the increase, hence the need to identify possible ameliorative agents. The present study evaluates the effects of the hydromethanol leaf extract of Craterispermum schweinfurthi on sperm characteristics and haematological indices in male wistar rats. A total of 20 male wistar rats weighing between 100-250g were randomly divided into 4 groups of 5 rats each and treated as follows for 28days: Group A: Negative control: Group B, C and D received 250mg/kgbw, 500mg/kg bw and 750mg/kg bw of extract. On day 29, the rats were placed under chloroform anaest

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Natasya Sushera, Ferren, Aprilia Yuanita Anwaristi, Ikmal Hafizi, and Nur Ariska Nugrahani. "Effect Of Coenzyme Q10 On Osteoblasts Cells Number In Male Wistar Rats Gingiva Undergoing Periodontitis." Jurnal EduHealth 14, no. 3 (2023): 1134–40. http://dx.doi.org/10.54209/jurnaleduhealth.v14i3.2521.

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Inflammatory conditions in periodontitis can lead to increased production of free radicals. This study aims to determine the effect of coenzyme Q10 on the number of osteoblast cells in the gingiva of male wistar rats with periodontitis. The method used in this research is true experimental laboratory with posttest only control group design. 24 male wistar rats were divided into 4 groups, negative control group and treatment group on days 7 and 14 with each group of 6 rats. Induction of periodontitis by tying using silk ligature in the subgingival area and induced Porphyromonas gingivalis bacte

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Schlenker, E. H., T. Tamura, and A. M. Gerdes. "Gender-specific effects of thyroid hormones on cardiopulmonary function in SHHF rats." Journal of Applied Physiology 95, no. 6 (2003): 2292–98. http://dx.doi.org/10.1152/japplphysiol.00594.2003.

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Spontaneously hypertensive heart failure (SHHF) rats develop hypertension and heart failure. We hypothesized that induction of hyperthyroidism should accelerate development of heart failure in male SHHF rats. Male and female SHHF rats received diets containing desiccated thyroid glands (DTG) or a control diet for 8 wk. Male and female Wistar-Kyoto rats were used as normotensive controls. DTG treatment reduced body weight in male, but not female, SHHF rats but increased body temperature and heart weight-to-body weight ratio in both genders. In DTG-treated male SHHF rats, serum triiodothyronine

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Mayasari, Shinta, and Lindawati Setyaningrum. "Effectiveness Of Antihypercholesterolemia Ethanol Extract Of Bay Leaf (Syzygyum Polyanthum) In Male Rats With Diabetes Mellitus Strain Wistar." Jurnal Kesehatan dr. Soebandi 10, no. 1 (2022): 33–38. http://dx.doi.org/10.36858/jkds.v10i1.331.

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Introduction: Cholesterol was one part of fat as one of the nutrients that the body needs and a high calorie producer. Plants made from natural ingredients, for example, bay leaves contain high flavonoids and are hypolipidemic as well as antioxidants that can inhibit oxidative stress. Objective: This study aims to to determine the effectiveness of the ethanol extract of bay leaves (Syzygyum polyanthum) against male white rats wistar strain diabetes mellitus with hypercholesterolemia. Methode: The experimental animals used were male wistar rats induced with streptozotocin at a dose of 30mg/kg B

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Okoronkwo, C.A., O.E. Edebiri, A. Ogedegbe, et al. "The Histological Effects of Chloroquine on the Kidney in Male wistar Rats." Research and Reviews in Intensive and Critical Care Nursing 3, no. 2 (2024): 13–21. https://doi.org/10.5281/zenodo.15463364.

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<em>The aim of this study is to determine the histological effects of chloroquine on the Kidney in Male wistar Rats. Twenty (20) adult wistar rat (weighing 195g) were used for the study. The animals were randomly assigned into four group with five rats in each group. Group A was tag as control, while B, C, and D were labeled as test groups. Group A control was not given other thing but water and field. Group B was given chloroquine once a day for 7 days; animal in group C were given chloroquine once in a day for 14 days, while group D animals given chloroquine once in a day for 21 days. All th

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Calabrese, Edward J., Denise A. Leonard, Xiaoqiang Zhao, and Kamala Lakshmanan. "Role of Tissue Repair in Carbon Tetrachloride Hepatotoxicity in Male and Female Sprague-Dawley and Wistar Rats." Journal of the American College of Toxicology 15, no. 1 (1996): 62–69. http://dx.doi.org/10.3109/10915819609008707.

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This study was designed to assess the hypothesis that large differences between male and female Wistar and Sprague-Dawley rats in susceptibility to carbon tetrachloride (CCl4)-induced hepatotoxicity are related to the differential capacity to repair tissue damage. This hypothesis was evaluated via two complementary approaches, (a) Separate groups of rats were administered a minimum lethal dose (LD10) of CC14, with colchicine (CLC) given at 24, 48, or 72 h after CCl4, and assessed for survival, (b) Rats were given a modestly hepatotoxic dose of CC14 and evaluated in terms of the rate and magnit

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Susanti, Yuyun Erlina, Bambang Wirjatmadi, and Merryana Adriani. "Pengaruh ekstrak melon terhadap kadar HbCO pada tikus Wistar jantan yang dipapar asap rokok." Jurnal Gizi Klinik Indonesia 13, no. 3 (2017): 105. http://dx.doi.org/10.22146/ijcn.17832.

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Background: Smoking is something that is usual for most Indonesian society, especially adult males. According to Riskesdas, smoking behavior of the population trends to increase. A previous study suggested that exposure to cigarette smoke produce CO bond to hemoglobin. Melon (Cucumis melo) contains antioxidants that prevent tissue damage.Objective: Analyze differences in levels HbCO Wistar male rats in treated and untreated extracts of melon.Method: The research was a laboratory experiment with the post test control group design and complete random design. The subjects were 25 male Wistar rats

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Diarti, Maruni Wiwin, Erlin Yustin Tatontos, Yunan Jiwintarum, and Anggun Sari Mianti. "THE EFFECT OF MELON SEEDS FLOUR (Cucumis Melo L.) TOWARD TOTAL CHOLESTEROL LEVEL IN WHITE MALE WISTAR STRAIN RATS (Rattus Norvegicus)." Jurnal Kesehatan Prima 12, no. 2 (2018): 151. http://dx.doi.org/10.32807/jkp.v12i2.188.

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Abstract: Cholesterol is an important element in the body, but in high quantities, it can cause atherosclerosis that will eventually possess an impact on coronary heart disease. One of the foods that can reduce cholesterol is a food contains flavonoids which is found in melon seeds (Cucumis melo l.). It contains high fiber that can reduce either of excessive insulin or blood fat levels. The objective study was to determine the effect of Melon seeds flour Toward Total Cholesterol Level in White Male Wistar Strain Rats. This research was carried out with pre-expriment research design, used One g

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Egbono, Frank Fubara, Enigheni Andrew Alali, and Dr Ruth Obomanu Tamunotonjo. "Effect of Caffeine on Stress Biomarkers on Male Wister Rats." Saudi Journal of Biomedical Research 8, no. 05 (2023): 50–56. http://dx.doi.org/10.36348/sjbr.2023.v08i05.001.

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Caffeine is widely consumed by the world population because its presence in major constitute of beverages like coffee and tea. This study was aimed at determining the biochemical effect on caffeine consumption in male wistar rats. This was a case-control study of the effect of exposing 180gram-220gram male wistar rats to caffeine for 3 days. Blood cortisol, FBG and FBC were measured in all the animals. Serum cortisol was significantly lower in the control group (P<0.001) and there was a significant weight loss in the caffeine-treated rats (P<0.001). Caffeine consumption had a significant

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Khvatov, Ivan A., Polina N. Ganza, Alexander N. Kharitonov, and Maria V. Samuleeva. "Wistar Male Rats (Rattus norvegicus domestica) Are Aware of Their Dimensions." Animals 14, no. 23 (2024): 3384. http://dx.doi.org/10.3390/ani14233384.

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Body size awareness is the ability of animals to consider the size of their bodies when interacting with environmental objects. It is one of the manifestations of body self-awareness. We studied body size awareness in laboratory rats of Wistar strain. In the experiment, rats had to pass through one of three holes in a partition to reach the bait. In each trial, the shape, size, and position of the holes varied. The task of the first experiment was to establish whether rats prefer to pass through the larger holes, given that all the three were penetrable for their bodies. The task of the second

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Santos, Ehebha Ehizokhale, Ogwu Chineye Sylvia, Obohwemu Oberhiri Kennedy, and Egbowawa Ufuoma Pearl. "HISTOLOGICAL EVALUATION OF THE EFFECTS OF ACTION BITTERS ON THE TESTES OF ADULT MALE WISTAR RATS." American Journal of Interdisciplinary Innovations and Research 06, no. 11 (2024): 194–203. http://dx.doi.org/10.37547/tajiir/volume06issue11-11.

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Action Bitters, a popular herbal concoction, has been traditionally used to treat various health conditions, including those related to the male reproductive system. Despite its widespread use, there is a dearth of scientific evidence on its effects on the testes. This study aimed to investigate the histological changes in the testes of adult male Wistar rats following administration of Action Bitters. Methods: Fifteen adult male Wistar rats were randomly divided into three groups (n = 5). Group A served as the normal control, while groups B and C received 10% (0.66ml/kg) and 5% (0.33ml/kg) le

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Irawan, Muhammad Andi, Antje Irmella Tarigan, and Siti Aisyah Dalimunthe. "The Effect of Administering Kelor Flower (Moringa Oleifera) Extract on Reducing Cholesterol Levels and Histopathological Features of The Testis of White Rats (Rattus norvegicus) Male Wistar Strain Obesity." International Journal of Public Health Excellence (IJPHE) 3, no. 2 (2024): 597–606. http://dx.doi.org/10.55299/ijphe.v3i2.756.

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Obesity and high cholesterol levels have garnered clinical attention for male infertility. The numerous compounds in Kelor flowers or Moringa make it a potential cholesterol medication. The research data were analyzed using SPSS, and the study was conducted as a true experiment using test animal samples of twenty-four male Wistar rats (Rattus norvegicus). The purpose of this study was to examine the histopathological features of obese male Wistar rats (Rattus norvegicus) and to determine whether or not the administration of Kelor flower extract (Moringa ternatea) reduced cholesterol levels and

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Okekpa, U.O., O.E. Edebiri, M.O. Oyakhire, et al. "The Histological Effects of Marijuana in the Kidney of Male Wistar Rats." Research and Reviews: Journal of Forensic Nursing 3, no. 1 (2025): 38–49. https://doi.org/10.5281/zenodo.15281185.

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<em>Marijuana, derived from the Cannabis sativa plant, has garnered increased attention in recent years due to its widespread use for recreational and medicinal purposes. </em><em>Given the widespread use and potential misuse of marijuana, as well as the ongoing research into its harmful effects, particularly concerning kidney injuries, there is a notable lack of scientific literature on how cannabis affects kidney histology.</em><em> As a result, </em><em>the histological effects of marijuana in the kidney of male wistar rats was carried out in this study. A total of twenty (20) adult male wi

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Onochie, A. U., V. O. Mamah, and J. C. Ifemeje. "Biochemical Evaluations of Male Wistar Rats Exposed to Pesticides." Tropical Journal of Applied Natural Sciences 2, no. 2 (2018): 119–25. http://dx.doi.org/10.25240/tjans.2018.2.2.15.

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Sayama, M., M. A. Mori, Y. Maruyama, M. Inoue, and H. Kozuka. "Intestinal transformation of 2,6-dinitrotoluene in male Wistar rats." Xenobiotica 23, no. 2 (1993): 123–31. http://dx.doi.org/10.3109/00498259309059368.

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Mahalmani, Vidya M., Anil P. Hogade, and Sanjay K. Mishra. "Effect of sitagliptin on depression in male wistar rats." International Journal of Basic & Clinical Pharmacology 9, no. 1 (2019): 200. http://dx.doi.org/10.18203/2319-2003.ijbcp20195787.

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Background: Growing evidence supports relationship between depression and inflammation. The hypothesis of involvement of inflammatory pathways in depression is supported by the findings of increased levels of proinflammatory cytokines. So, we decided to evaluate the effect of sitagliptin on depression using forced swim test (FST) and possible effects of sitagliptin on serum oxidative stress markers and cytokine gene expression in rat hippocampus.Methods: FST model was used to evaluate antidepressant effect in male wistar rats. Rats in group I (control group) were given normal saline, group II

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Newby, F. D., M. DiGirolamo, G. A. Cotsonis, and M. H. Kutner. "Model of spontaneous obesity in aging male Wistar rats." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 259, no. 6 (1990): R1117—R1125. http://dx.doi.org/10.1152/ajpregu.1990.259.6.r1117.

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We analyzed retrospectively data from 148 chow-fed male Wistar rats killed between the age of 6 wk and 2 yr while varying in body weight from 136 to 917 g. The purpose of this study was to clarify the relationship of body weight and body lipid content with the composition and cellularity of the epididymal and retroperitoneal fat depots. A positive linear association was found between body weight and body water or fat-free dry residue, whereas total body lipid exhibited a curvilinear relationship with body weight. The weight of the epididymal pads was linearly related to body weight but not to

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Miachon, S., S. Augier, M. Jouvenet, P. Boucher, and J. J. Vallon. "Nutritional parameters modify muricidal behavior of male Wistar rats." Life Sciences 69, no. 23 (2001): 2745–57. http://dx.doi.org/10.1016/s0024-3205(01)01344-3.

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Kasuba, Vilena, Davor Zeljezic, Marin Mladinic, et al. "Genotoxic effects of ZnO nanoparticles in male wistar rats." Toxicology Letters 229 (September 2014): S194. http://dx.doi.org/10.1016/j.toxlet.2014.06.658.

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Ivanova, L., N. Shepelskaya, M. Prodanchuk, I. Lepeshkin, and O. Kravchuk. "Age-dependent gonadotoxicity of carbofuran in male Wistar rats." Toxicology Letters 238, no. 2 (2015): S343. http://dx.doi.org/10.1016/j.toxlet.2015.08.980.

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Tulinska, J., A. Sovcikova, A. Liskova, J. Kubova, and K. Horakova. "Immunotoxicity of ethyl-4-isothiocyanatobutanoate in male Wistar rats." Toxicology 145, no. 2-3 (2000): 217–25. http://dx.doi.org/10.1016/s0300-483x(99)00225-5.

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Certa, H., N. Fedtke, H. J. Wiegand, A. M. F. Müller, and H. M. Bolt. "Toxicokinetics of p -tert-octylphenol in male Wistar rats." Archives of Toxicology 71, no. 1-2 (1996): 112–22. http://dx.doi.org/10.1007/s002040050365.

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