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1

PONZONE, ALBERTO, ROBERTO FERRERO, and PAOLO AROSIO. "Mamary Control of Iron Secretion in Milk." Annals of the New York Academy of Sciences 464, no. 1 Endocrinology (1986): 470–72. http://dx.doi.org/10.1111/j.1749-6632.1986.tb16039.x.

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2

Sriyati, Sriyati, and Yeni Kartika Sari. "The Effect of Back Massage to Breastmilk Production of Post Partum Mother in Cempaka Room Ngudi Waluyo Wlingi Hospital." Jurnal Ners dan Kebidanan (Journal of Ners and Midwifery) 2, no. 2 (2015): 136–43. http://dx.doi.org/10.26699/jnk.v2i2.art.p136-143.

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Breast milk is an emulsion of fat in the protein solution, laktosa, and inorganic salts secreted by the mamary glands of the mother. The oxytocin hormone is a hormone that affects of lactation process. Oxytocin is up to the alveoli of the mammry myoepithelial cell contraction causes surrounding the mammary alveoli and lactiferous ducts. Back massage on cervical 5-6 until the bottom of the shoulder blade stimulate endorphins and oxytocin secretion and improves blood circulation breast area. The purpose of research to determine the effect of back massage on milk production an mothers post partum
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3

Heap, R. B., I. R. Fleet, M. Hamon, J. M. Booth, and V. M. Chaplin. "Hormone changes in milk at the onset of lactogenesis and parturition in Friesland sheep." Journal of Agricultural Science 106, no. 2 (1986): 265–69. http://dx.doi.org/10.1017/s002185960006384x.

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SUMMARYOestrone sulphate, progesterone, total protein, Na and K concentrations in mammary secretions of Friesland sheep have been determined from 11 days before until 8 days after parturition. Mammary secretions were obtained on most days for at least 1 week before parturition in 9 of 14 ewes, and in all animals after lambing. Oestrone sulphate concentration had doubled on the morning of parturition compared with the value 24 h earlier, and this sharp rise was a useful indicator that delivery was imminent. Values continued to rise during the day of delivery, remained high for a further 24 h an
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4

Watanabe, Atsushi, Jiro Hirota, Shinya Shimizu, Shigeki Inumaru, and Kazuhiro Kimura. "Single Intramammary Infusion of Recombinant Bovine Interleukin-8 at Dry-Off Induces the Prolonged Secretion of Leukocyte Elastase, Inflammatory Lactoferrin-Derived Peptides, and Interleukin-8 in Dairy Cows." Veterinary Medicine International 2012 (2012): 1–8. http://dx.doi.org/10.1155/2012/172072.

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A single intramammary infusion of recombinant bovine interleukin-8 (IL-8) at 50 μg/quarter/head, but not 10 μg/quarter/head, induced clinical mastitis in three of four cows during the dry-off period, resulting in an elevated rectal temperature, redness and swelling of the mammary gland, extensive polymorphonuclear leukocyte (PMNL) infiltration, and milk clot formation from 1 to 28 days post infusion (PI). In the mammary secretions of the mastitic glands, high levels of IL-8 were sustained from 8 hours to 28 days PI, peaking at 1–3 days PI. The levels of leukocyte-derived elastase and inflammat
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5

Ho, Chin H., Chai J. Chang, Wen B. Liu, et al. "In situ generation of milk protein-derived peptides in drying-off cows." Journal of Dairy Research 77, no. 4 (2010): 487–97. http://dx.doi.org/10.1017/s0022029910000634.

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Our previous studies demonstrated prompt elevation of proteinase activity in mammary secretion of drying-off cows and goats. The current study examined the progressive changes in composition of cow mammary secretion following drying-off and, in parallel, characterized the mode of peptide neogenesis using matrix-assisted laser desorption ionization-time-of-flight mass spectrometry (MALDI-TOF MS) and liquid chromatography-electrospray-ionization (LC-ESI) MS/MS. The results show that the percentage of casein of total milk protein at time of drying-off was 76%, which dropped to 41%, 24%, and 16%,
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6

Barrington, GM, TE Besser, CC Gay, et al. "Regulation of the immunoglobulin G1 receptor: effect of prolactin on in vivo expression of the bovine mammary immunoglobulin G1 receptor." Journal of Endocrinology 163, no. 1 (1999): 25–31. http://dx.doi.org/10.1677/joe.0.1630025.

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Induction of colostrogenesis in non-pregnant cows was used to evaluate the relationship between prolactin (PRL) and mammary immunoglobulin G1 (IgG1) receptor expression. Six of eleven non-pregnant, non-lactating Holstein cattle responded to a standard lactation induction protocol by development of elevated IgG1 concentrations in mammary secretions. In order to increase the diversity in PRL concentrations, two of the six cattle were treated with bromocriptine, and two others were treated with recombinant bovine PRL. Serum alpha-lactalbumin, serum PRL and mammary secretion IgG1 concentrations we
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7

Wilson, Eric, and Eugene C. Butcher. "CCL28 Controls Immunoglobulin (Ig)A Plasma Cell Accumulation in the Lactating Mammary Gland and IgA Antibody Transfer to the Neonate." Journal of Experimental Medicine 200, no. 6 (2004): 805–9. http://dx.doi.org/10.1084/jem.20041069.

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The accumulation of immunoglobulin (Ig)A antibody-secreting cells (ASCs) in the lactating mammary gland leads to secretion of antibodies into milk and their passive transfer to the suckling newborn. This transfer of IgA from mother to infant provides transient immune protection against a variety of gastrointestinal pathogens. Here we show that the mucosal epithelial chemokine CCL28 is up-regulated in the mammary gland during lactation and that IgA ASCs from this tissue express CCR10 and migrate to CCL28. In vivo treatment with anti-CCL28 antibody blocks IgA ASC accumulation in the mammary glan
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8

Varatanovic, Nazif, Amela Katica, Tarik Mutevelic, Nadzida Mlaco, and Edin Hamzic. "Analysis of mammary gland according to results of CMT (California Mastitis Test) and bacteriological findings in secretion." Veterinarski glasnik 63, no. 5-6 (2009): 359–67. http://dx.doi.org/10.2298/vetgl0906359v.

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Health control of the mammary gland was conducted comparing results of CMT (California Mastitis Test) and bacteriological findings of milk samples during one year. A total of 3863 secretion samples of mammary glands were collected. There were 85.3% matches for CMT and bacteriological findings. The most frequently isolated causative agents were: staphylococci (52.4%), streptococcus bacteria (23.5%), mixed infections (13.1%), and enterobacteria (10.3%). Secretions disorder and inflammations of mammary gland are most common for the warm period of the year, and very rare for the winter period. Wit
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9

McCormick, Nicholas H., and Shannon L. Kelleher. "ZnT4 provides zinc to zinc-dependent proteins in the trans-Golgi network critical for cell function and Zn export in mammary epithelial cells." American Journal of Physiology-Cell Physiology 303, no. 3 (2012): C291—C297. http://dx.doi.org/10.1152/ajpcell.00443.2011.

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Zinc (Zn) transporter 4 (ZnT4) plays a key role in mammary gland Zn metabolism. A mutation in ZnT4 ( SLC30A4) that targets the protein for degradation is responsible for the “lethal milk” ( lm/lm) mouse phenotype. ZnT4 protein is only detected in the secreting mammary gland, and lm/lm mice have ∼35% less Zn in milk, decreased mammary gland size, and decreased milk secretion. However, the precise contribution of ZnT4 is unknown. We used cultured mouse mammary epithelial cells (HC11) and determined that ZnT4 was localized to the trans-Golgi network (TGN) and cell membrane and transported Zn from
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10

Lyster, R. L. J. "Mammary gland secretion." Transactions of the Zoological Society of London 33, no. 2 (2010): 141–45. http://dx.doi.org/10.1111/j.1096-3642.1976.tb00046.x.

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11

Freeman, ME. "The Nonpregnant Uterus as an Endocrine Organ." Physiology 3, no. 1 (1988): 31–32. http://dx.doi.org/10.1152/physiologyonline.1988.3.1.31.

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The mammalian uterus is well known as an endocrine organ whose secretions are responsible for the maintenance of pregnancy and the preparation of the mammary gland for lactation. There is now evidence that the nonpregnant uterus secretes a hormone that regulates pituitary function in the nonpregnant mammal. It secretes a protein that enters the bloodstream and is transported to the pituitary gland where it acts to inhibit prolactin secretion.
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12

Stewart, Harriet J., and Felicity M. Maule Walker. "ACTH initiation of mammary secretion in pregnant goats is influenced by the stage of gestation and pre partum milking." Journal of Dairy Research 54, no. 2 (1987): 179–91. http://dx.doi.org/10.1017/s0022029900025322.

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SummaryPregnant goats were treated with ACTH by intramuscular injection (1 mg/d for 2 d) at various stages of pregnancy to investigate its effect on initiation of mammary secretion. ACTH stimulated lactose secretion and increased udder volume at or after 84 d of gestation, when compared with untreated controls. Treatment with ACTH between d 109 and 127 of gestation increased circulating plasma glucose concentration, mammary blood flow and mammary uptake of glucose which returned to pre injection levels 6 d after treatment. Arterial concentrations of progesterone were not affected by ACTH but m
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13

Kostenko, V. I. "ON THE MATTER OF MILK SECRETION INTENSITY BY COW’S MAMMARY GLAND." Animal Science and Food Technology 11, no. 4 (2020): 54–60. http://dx.doi.org/10.31548/animal2020.04.054.

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The secretion of milk in the intervals between milkings has its own patterns, and therefore researchers have different opinions about the intensity of the secretory process. Some scientists believe that the secretion of milk is uneven. Immediately after emptying the udder, it is higher, and with increasing interval, the intensity of the secretory process decreases, i.e. it is curved. This issue is still not clarified scientifically. The aim of our research was to study the change in the intensity of milk secretions during lactation under the condition of "voluntary", physiologically motivated
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14

Marshall, Valerie M. E., Wendy M. Cole, and A. John Bramley. "Influence of the lactoperoxidase system on susceptibility of the udder toStreptococcus uberisinfection." Journal of Dairy Research 53, no. 4 (1986): 507–14. http://dx.doi.org/10.1017/s0022029900033033.

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SummaryLactoperoxidase (LP), thiocyanate (SCN-), pH and somatic cell counts (SCC) were measured in mammary secretions from 20 cows collected 14 d before drying-off, 7 and 21 d after drying-off, and 3–18 d postcalving. The inhibitory activity of the secretions onStreptococcus uberiswas determined and the susceptibility of the udder to infection by this organism was tested by intramammary infusion of 250 colony forming units at the above stages. LP, SCN-, pH and SCO increased during involution and fell postcalving. The secretions collected before drying-off, 7 d after drying-off and postcalving
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15

Hadsell, D. L., C. R. Baumrucker, and R. S. Kensinger. "Effects of elevated blood insulin-like growth factor-I (IGF-I) concentration upon IGF-I in bovine mammary secretions during the colostrum phase." Journal of Endocrinology 137, no. 2 (1993): 223–30. http://dx.doi.org/10.1677/joe.0.1370223.

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ABSTRACT The objectives of these studies were to determine if the concentration of insulin-like growth factor-I (IGF-I) in mammary colostrum secretions could be altered through manipulation of IGF-I concentrations in blood and to compare the temporal changes of IGF-I in mammary secretions to those occurring for IgG1. Milking of 15 pregnant Holstein cows was stopped at 8 weeks prepartum and they were randomly assigned to one of three treatments. A control (C) treatment consisted of feeding the animals 100% of NRC requirements for protein and energy. A second group of cows was fed as the control
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16

Sudlow, A. W., C. J. Wilde та R. D. Burgoyne. "Transforming growth factor-β1 inhibits casein secretion from differentiating mammary-gland explants but not from lactating mammary cells". Biochemical Journal 304, № 2 (1994): 333–36. http://dx.doi.org/10.1042/bj3040333.

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Transforming growth factor-beta (TGF beta) is important in the maturation and function of the mammary gland and is present in milk. We have examined whether, in addition to inhibiting lactogenesis, TGF beta exerts acute regulatory effects on lactating mammary cells. The isoform TGF beta 1 at 5 and 50 ng/ml suppressed the onset of lactation and the subsequent production of beta-casein by differentiating mouse mammary explants from pregnant mice. By contrast, it did not inhibit protein synthesis or secretion from acini isolated from lactating-mouse mammary gland or protein secretion from explant
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17

Wilde, C. J., and M. Peaker. "Autocrine control in milk secretion." Journal of Agricultural Science 114, no. 3 (1990): 235–38. http://dx.doi.org/10.1017/s0021859600072592.

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The mammary gland is controlled at two levels in the body. The genetically controlled pattern of parental investment during lactation is modified by nutritional status and signalled to the mammary gland by the endocrine system (see Peaker 1989). The response to this strategic control of the rate of milk secretion is modulated by a tactical control mechanism operating within each mammary gland. The local intramammary mechanism responds to changes in the frequency or completeness of milk removal and acts to match the rate of milk secretion to the rate of milk removal by the young or, in dairy an
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18

Thompson, Gordon E. "Local control of the onset of mammary extraction of plasma triglycerides during lactogenesis in the goat." Journal of Dairy Research 57, no. 4 (1990): 489–93. http://dx.doi.org/10.1017/s0022029900029538.

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SummaryIn five untreated goats, mammary extraction of plasma triglycerides increased at parturition. In five goats that had as much secretion as possible regularly removed from one mammary gland beginning on d 143 of gestation, the change of triglyceride extraction occurred several d before parturition in the emptied gland but at parturition in the contralateral control gland. The experimentally induced early increase of extraction of plasma triglycerides preceded the increase of prostaglandin Fα concentration in mammary secretion at parturition, and occurred despite abnormally high concentrat
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19

Chou, Wen K., Ting C. Yu, Shuen E. Chen та ін. "TNFα-mediated plasminogen activation on neutrophils is involved in the high plasmin activity in mammary secretion of drying-off cows". Journal of Dairy Research 76, № 4 (2009): 459–68. http://dx.doi.org/10.1017/s0022029909990069.

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Interactions between inflammatory cytokines and plasminogen (Pg) activation system on immune cells are yet to be established. In previous studies we reported a somatic cell-associated elevation of proteolytic activity in mammary secretion of drying-off goats and cows. The purposes of the present study were to examine the role of TNF-α in polymorphonuclear neutrophil (PMN)-associated Pg activation, and the significance of this activation pathway for overall plasmin (Pm) activity in mammary secretion of drying-off cows. Results of experiments in vitro showed that the spontaneous Pg activation ob
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20

McManaman, James L., and Margaret C. Neville. "Mammary physiology and milk secretion." Advanced Drug Delivery Reviews 55, no. 5 (2003): 629–41. http://dx.doi.org/10.1016/s0169-409x(03)00033-4.

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21

Passchyn, Pieter, Sofie Piepers, Ellen Schmitt-Van de Leemput, Christian Guidarini, and Sarne De Vliegher. "Concentration of penicillin G in mammary tissue and secretion of end-term dairy heifers following systemic prepartum administration of penethamate hydriodide." Journal of Dairy Research 77, no. 1 (2009): 33–36. http://dx.doi.org/10.1017/s0022029909990288.

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The aim of this study was to assess the concentration of penicillin G in mammary tissue and secretion of dry heifers following systemic administration of penethamate hydriodide. Six dairy heifers in late gestation received a single intramuscular injection of 10 g penethamate hydriodide and were sacrificed 24, 48 or 144 h after treatment. Penicillin G concentrations were measured in mammary tissue and secretion samples using HPLC. Penicillin G was detected in the udder of two animals euthanized at 24 h (mammary tissue and secretion) and at 48 h post treatment (mammary secretion only) after admi
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22

Wilde, C. J., C. V. P. Addey, L. M. Boddy, and M. Peaker. "Autocrine regulation of milk secretion by a protein in milk." Biochemical Journal 305, no. 1 (1995): 51–58. http://dx.doi.org/10.1042/bj3050051.

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Frequency or completeness of milk removal from the lactating mammary gland regulates the rate of milk secretion by a mechanism which is local, chemical and inhibitory in nature. Screening of goat's milk proteins in rabbit mammary explant cultures identified a single whey protein of M(r) 7600 able to inhibit synthesis of milk constituents. The active whey protein, which we term FIL (Feedback inhibitor of Lactation), also decreased milk secretion temporarily when introduced into a mammary gland of lactating goats. FIL was synthesized by primary cultures of goat mammary epithelial cells, and was
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23

Holmes, Mark A., and Peter E. Hartmann. "Concentration of citrate in the mammary secretion of sows during lactogenesis II and established lactation." Journal of Dairy Research 60, no. 3 (1993): 319–26. http://dx.doi.org/10.1017/s0022029900027667.

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SummaryThe functional significance of citrate in the mammary secretion of six sows was investigated during the second stage of lactogenesis (lactogenesis II) and established lactation. The changes in the concentrations of progesterone and lactose in the maternal blood, and lactose, Na and K in the mammary secretion, suggested that lactogenesis II began during the final day of pregnancy. The concentration of citrate in the mammary secretion of the sows during lactogenesis II was high and varied from 5·4 (SEM 0·5) mai at day 0·5 post partum to 6·8 (SEM 0·4) mM at day 1·5 post partum. There was a
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24

McManaman, James L. "Milk lipid secretion: recent biomolecular aspects." BioMolecular Concepts 3, no. 6 (2012): 581–91. http://dx.doi.org/10.1515/bmc-2012-0025.

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AbstractNeonates of most species depend on milk lipids for calories, fat-soluble vitamins, and bioactive lipid components for growth and development during the postnatal period. To meet neonatal nutrition and development needs, the mammary gland has evolved efficient mechanisms for synthesizing and secreting large quantities of lipid during lactation. Although the biochemical steps involved in milk lipid synthesis are understood, the identities of the genes mediating these steps and the molecular physiology of milk lipid production and secretion have only recently begun to be understood in det
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25

Feuermann, Yonatan, Sameer J. Mabjeesh, and Avi Shamay. "Mammary Fat Can Adjust Prolactin Effect on Mammary Epithelial Cells via Leptin and Estrogen." International Journal of Endocrinology 2009 (2009): 1–8. http://dx.doi.org/10.1155/2009/427260.

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Leptin, like estrogen, is one of the endo/paracrine factors, which are synthesized in and secreted from mature adipocytes. The roles of the mammary fat pad and mammary adipocytes in the initiation of lactation are not clear. In this study, we showed that combination of prolactin, leptin and estrogen elevated the expression of the milk protein beta-lactoglobulin. We also showed that after prolactin stimulate the secretion of leptin from the mammary fat, leptin upregulated the expression of estrogen receptor alpha in the mammary epithelial cells. Also, prolactin affected aromatase mRNA expressio
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RINCHEV-ALARNOLD, AURORE, LUCETTE BELAIR, and JEAN DJIANE. "Developmental expression of pIgR gene in sheep mammary gland and hormonal regulation." Journal of Dairy Research 69, no. 1 (2002): 13–26. http://dx.doi.org/10.1017/s0022029901005362.

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Secretory IgA found in external secretions are constituted by polymeric IgA (pIgA) bound to the extra-cellular part of the polymeric immunoglobulin receptor (pIgR). The receptor mediates transcytosis of pIgA across epithelial cells. The aim of the present study was to analyse the evolution of pIgR expression in the sheep mammary gland during the development of the mammary gland and to analyse its hormonal regulation. Gene expression of the pIgR was analysed in sheep mammary gland during pregnancy and lactation. By Northern Blot analysis, we observed that low levels of pIgR mRNA are expressed u
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27

Neville, MC. "Mammary Cultures on Floating Gels: A Model System for Mammary Function." Physiology 2, no. 3 (1987): 107–11. http://dx.doi.org/10.1152/physiologyonline.1987.2.3.107.

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Cultures of mammary epithelium on collagen gels can be induced to secrete the normal complement of milk proteins if the gels are released from the culture dish, allowing them to contract. During the contraction the epithelial cells undergo a shape change from flattened to columnar that initiates secretion of milk proteins. These floating cultures are dependent on hormones and offer a valuable model system for the study of milk secretion and its regulation.
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Thompson, Gordon E., and Jane A. Goode. "Pre partum milk fat secretion and concentrations of progestins, prostaglandin and oestrone sulphate in mammary fluid of the goat." Journal of Dairy Research 54, no. 2 (1987): 193–97. http://dx.doi.org/10.1017/s0022029900025334.

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SummaryAs much secretion as possible was removed manually twice daily, from both mammary glands of 6 late-pregnant goats beginning on d 137 of gestation. Removing mammary fluid before parturition stimulated fluid secretion by different amounts in individual goats. The mean volume of fluid secreted pre partum by the goats correlated directly with their secretion of triglyceride and the percentage composition of C18 fatty acids in the triglyceride fatty acids; the volume also correlated with the concentration of progestins, but not prostaglandin F2α or oestrone sulphate, in the fluid.
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Barber, Michele R., and T. J. Yang. "Chemotactic Activities in Nonmastitic and Mastitic Mammary Secretions: Presence of Interleukin-8 in Mastitic but Not Nonmastitic Secretions." Clinical Diagnostic Laboratory Immunology 5, no. 1 (1998): 82–86. http://dx.doi.org/10.1128/cdli.5.1.82-86.1998.

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ABSTRACT Due to its association with low-quality milk and a decrease in milk production in bovines, mastitis is a major cause of economic loss. Additionally, mastitis can be harmful to suckling newborns and can cause damage to the mammary gland. In mastitic mammary secretions there is a substantial increase in somatic cells, specifically neutrophils. In this study we examined the ability of mastitic and nonmastitic mammary secretions to cause in vitro neutrophil chemotaxis using a microchemotaxis assay. Also, the role of the inflammatory chemokine interleukin-8 (IL-8) in neutrophil recruitment
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30

Thompson, Gordon, and Anne Faulkner. "The onset of mammary secretion of medium-chain-length triglyceride fatty acids in the cow milked pre-partum." Journal of Dairy Research 57, no. 1 (1990): 1–5. http://dx.doi.org/10.1017/s0022029900026546.

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SummarySix Friesian cows were milked daily, and arterial and mammary venous blood samples were taken between day 266 of gestation and day 6 after parturition. Samples of blood plasma were analysed for their content of acetate and progesterone, and mammary secretion for potassium, isocitrate, 2-oxoglutarate and triglyceride fatty acids.The onset of secretion of medium-chain triglyceride fatty acids was preceded by, or coincided with, increases of potassium and isocitrate concentration in the secretion. The onset of fatty acid secretion was not accompanied by any change in the gland's extraction
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31

Poonsuk, Korakrit, and Jeff Zimmerman. "Historical and contemporary aspects of maternal immunity in swine." Animal Health Research Reviews 19, no. 1 (2017): 31–45. http://dx.doi.org/10.1017/s1466252317000123.

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AbstractMaternal immunity plays a pivotal role in swine health and production because piglets are born agammaglobulinemic and with limited cell-mediated immunity, i.e. few peripheral lymphoid cells, immature lymphoid tissues, and no effector and memory T-lymphocytes. Swine do not become fully immunologically competent until about 4 weeks of age, which means that their compromised ability to respond to infectious agents during the first month of life must be supplemented by maternal immune components: (1) circulating antibodies derived from colostrum; (2) mucosal antibodies from colostrum and m
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Isakova, M. N., U. V. Sivkova, M. V. Ryaposova, I. A. Shkuratova, and A. V. Lysov. "Quality profile of milk from high producing dairy cows vaccinated against mastitis." Veterinary Science Today, no. 4 (January 13, 2021): 255–60. http://dx.doi.org/10.29326/2304-196x-2020-4-35-255-260.

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One of the raw milk quality criteria is the count of somatic cells, produced by the cow’s immune system to fight infectious diseases of the mammary gland. The paper presents the analysis of somatic cell count and total bacteria count of milk from cows, vaccinated against mastitis using Startvac vaccine. Tests were performed as a comparison between a dairy unit and a farm under different management conditions and using different milking techniques. Six months after the start of the vaccine application the somatic cell count at the dairy unit decreased by 60 thousand/ml, at the farm by 182 thous
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Schollenberger, A., A. Degorski, T. Frymus, and Ada Schollenberger. "Cells of Sow Mammary Secretions." Journal of Veterinary Medicine Series A 33, no. 1-10 (1986): 31–38. http://dx.doi.org/10.1111/j.1439-0442.1986.tb00502.x.

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Schollenberger, A., T. Frymus, A. Degorski, and Ada Schollenberger. "Cells of Sow Mammary Secretions." Journal of Veterinary Medicine Series A 33, no. 1-10 (1986): 39–46. http://dx.doi.org/10.1111/j.1439-0442.1986.tb00503.x.

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35

Schollenberger, A., T. Frymus, A. Degórski, and Ada Schollenberger. "Cells of Sow Mammary Secretions." Journal of Veterinary Medicine Series A 33, no. 1-10 (1986): 353–59. http://dx.doi.org/10.1111/j.1439-0442.1986.tb00543.x.

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36

Turner, MD, ME Rennison, SE Handel, CJ Wilde, and RD Burgoyne. "Proteins are secreted by both constitutive and regulated secretory pathways in lactating mouse mammary epithelial cells." Journal of Cell Biology 117, no. 2 (1992): 269–78. http://dx.doi.org/10.1083/jcb.117.2.269.

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Lactating mammary epithelial cells secrete high levels of caseins and other milk proteins. The extent to which protein secretion from these cells occurs in a regulated fashion was examined in experiments on secretory acini isolated from the mammary glands of lactating mice at 10 d postpartum. Protein synthesis and secretion were assayed by following the incorporation or release, respectively, of [35S]methionine-labeled TCA-precipitable protein. The isolated cells incorporated [35S]methionine into protein linearly for at least 5 h with no discernible lag period. In contrast, protein secretion w
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THOMPSON, GORDON E., S. KHAWAR ABBAS, CARL HOLT, and ANTHONY D. CARE. "Cortisol, parathyroid hormone-related protein and the onset of calcium secretion by the mammary gland of the goat." Journal of Dairy Research 64, no. 4 (1997): 633–36. http://dx.doi.org/10.1017/s0022029997002409.

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During lactogenesis in the goat, the onset of secretion of calcium into milk occurs at parturition (Thompson et al. 1995) at approximately the same time as the onset of secretion of parathyroid hormone-related protein (PTHrP) by the mammary gland (Ratcliffe et al. 1992); these events may be unrelated or PTHrP may be involved in calcium transport from blood to milk.Parturition in goats is initiated by fetal secretion of cortisol (Flint et al. 1978) and maternal secretion of cortisol also increases (Paterson & Linzell, 1971). Injecting cortisol locally into the sinus of a mammary gland of th
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Pidada, I. B. Rai. "PENGARUH PEMBERIAN OKSITOSIN DAUN KATU DAN DAUN LAMPES TERHADAP SEKRESI AIR SUSU DAN GAMBARAN HISTOLOGI KELENJAR AMBING PADA MENCIT." Berkala Penelitian Hayati 5, no. 1 (1999): 1. http://dx.doi.org/10.23869/bphjbr.5.1.19991.

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A comparative study on the effect of oxytocin, extracted leaf of katu (Sauropus androgynous, Merr) and lampes (Ocimum sanctum, Linn) against secretions of milk and histologically mammary gland of mice was carried out under laboratory conditions. The study was designed by using totally 40 mice pp and divided into four groups treatment which consisted 10 females mice post partum (pp) of each group. The control group, katu (S.androginus), lampes (O. sanctum), and oxytosin were given orally 0.5 ml physiological solution, 10 mg/0.5 ml leaf extract of S. androgynus , 10 mg/0.5 ml leaf extract of O.
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39

Camussone, Cecilia M., Ana I. Molineri, Marcelo L. Signorini, Verónica E. Neder, Carlos A. Vitulich, and Luis F. Calvinho. "Risk factors of S. aureus intramammary infection in pre partum dairy heifers under grazing conditions and molecular characterization of isolates from heifers and cows." Journal of Dairy Research 87, no. 1 (2020): 82–88. http://dx.doi.org/10.1017/s0022029919001018.

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AbstractThe aims of the research reported here were to identify potential risk factors associated with the presence of Staphylococcus aureus intramammary infection (IMI) in pre partum dairy heifers on 17 dairy farms from three provinces of Argentina and to characterize, at molecular level, isolates from those heifers and lactating cows from two selected herds. A total of 1474 heifers and 4878 lactating cows were studied. The prevalence of Staphylococcus aureus IMI in the heifers, heifers at quarter level and lactating cow mammary quarters was 14.41, 4.82, and 14.65%, respectively. Univariate a
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40

Corps, A. N., D. M. Blakeley, J. Carr, L. H. Rees, and K. D. Brown. "Synergistic stimulation of Swiss mouse 3T3 fibroblasts by epidermal growth factor and other factors in human mammary secretions." Journal of Endocrinology 112, no. 1 (1987): 151–59. http://dx.doi.org/10.1677/joe.0.1120151.

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ABSTRACT The concentration of epidermal growth factor (EGF) in human mammary secretions was about 50 nmol/l for several weeks prepartum. It then fell to about 13 nmol/l within 4 days after parturition, in parallel with the decrease in protein concentration which is associated with the onset of lactation. In contrast, the concentration of EGF in urine samples from the same donors remained constant throughout this period. All the immunoreactive EGF in mammary secretions competed at the EGF receptors on Swiss mouse 3T3 fibroblasts. The stimulation of these cells by samples of mammary secretions w
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41

Steinetz, Bernard G., Lori Horton, and Sally Lasano. "The Source and Secretion of Immunoactive Relaxin in Rat Milk." Experimental Biology and Medicine 234, no. 5 (2009): 562–65. http://dx.doi.org/10.3181/0811-bc-341.

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The milk of many mammalian species contains hormones and growth factors in addition to nutrients and immuocompetent substances. These factors can be absorbed into the circulation of suckling neonates to exert important effects on metabolism and promote tissue and organ growth. Frequently, there is uncertainty as to whether such substances are gene products of the mammary glands themselves or are produced elsewhere and concentrated from the systemic circulation. The 6 kD polypeptide, relaxin, appears in milk of several mammalian species, including that of the rat, but proof of its source of sec
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Thompson, Gordon E. "Release of cholesteryl esters by the mammary gland of the pre-partum cow." Journal of Dairy Research 56, no. 2 (1989): 161–65. http://dx.doi.org/10.1017/s0022029900026376.

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SummaryIn five cows that were regularly milked before parturition, cholesteryl esters were continuously released into the mammary fluid; their concentration in the fluid was initially high, but decreased a few days before parturition when mammary secretion of fluid and triglyceride was increasing. The composition of fatty acids in the cholesteryl esters of mammary fluid and in blood plasma was different, suggesting mammary synthesis of cholesteryl esters.
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43

Ikawa, Hiroshi, Minoru Irahara, Toshiya Matsuzaki, Seiichiro Saito, Toshiaki Sano, and Toshihiro Aono. "Impaired induction of prolactin secretion from the anterior pituitary by suckling in streptozotocin-induced diabetic rat." Acta Endocrinologica 126, no. 2 (1992): 167–72. http://dx.doi.org/10.1530/acta.0.1260167.

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Prolactin (PRL) secretion in streptozotocin-induced diabetic rats postpartum was examined to elucidate the reason for the reduced milk secretion of diabetic mothers. Pregnant Wistar rats were given citrate buffer (control group) or streptozotocin only (DM group) or with insulin (insulin group). Growth of pups was significantly lower in the DM group than in the control group, but similar in the insulin and control groups. Suckling-induced PRL secretion was significantly lower in the DM group than in the control group, and intermediate in the insulin group. TRH-induced PRL secretion was signific
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44

Talhouk, R. S., J. R. Chin, E. N. Unemori, Z. Werb, and M. J. Bissell. "Proteinases of the mammary gland: developmental regulation in vivo and vectorial secretion in culture." Development 112, no. 2 (1991): 439–49. http://dx.doi.org/10.1242/dev.112.2.439.

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The extracellular matrix (ECM) is an important regulator of mammary epithelial cell function both in vivo and in culture. Substantial remodeling of ECM accompanies the structural changes in the mammary gland during gestation, lactation and involution. However, little is known about the nature of the enzymes and the processes involved. We have characterized and studied the regulation of cell-associated and secreted mammary gland proteinases active at neutral pH that may be involved in degradation of the ECM during the different stages of mammary development. Mammary tissue extracts from virgin
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45

Wilde, C. J., A. J. Clark, M. A. Kerr, C. H. Knight, M. McClenaghan та J. P. Simons. "Mammary development and milk secretion in transgenic mice expressing the sheep β-lactoglobulin gene". Biochemical Journal 284, № 3 (1992): 717–20. http://dx.doi.org/10.1042/bj2840717.

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Mammary development and milk secretion were studied in transgenic mice which exhibited mammary tissue-specific expression of the sheep beta-lactoglobulin gene, and secreted significant quantities of the foreign protein in milk. Mammary development was unaffected by transgenesis. Tissue DNA content and the activities of several key enzyme markers of cell differentiation were similar in transgenic mice and non-transgenic controls. Milk yield, whether estimated by pup weight gain or measured by a 3H2O-dilution method, was unchanged by foreign gene expression. Gross milk composition, including mil
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Radojkovic, Danijela, Slobodan Antic, Milica Pesic, et al. "Significance of hyperprolactinemia for cytomorphologic features of breast secretions." Vojnosanitetski pregled 67, no. 1 (2010): 42–47. http://dx.doi.org/10.2298/vsp1001042r.

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Background/Aim. Nipple discharge syndrome is a clinical entity capable of presenting various disorders such is mammary infection (nonpuerperal and puerperal mastitis), intraductal papillomas, fibrodenoma, breast cancer and hyperprolactinemia syndrome. The aim of the study was to determine differencies in cytological features of mammary secretion in patients with hyperprolactinemia and those with normal serum prolactin levels and to define the role of growth hormone, follicle-stimulating hormone, luteinizing hormone and thyroid-stimulating hormone in creating cellular profile of breast secretio
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47

Janowski, T., S. Zduńczyk, J. Małecki-Tepicht, W. Barański, and A. Raś. "Mammary secretion of oestrogens in the cow." Domestic Animal Endocrinology 23, no. 1-2 (2002): 125–37. http://dx.doi.org/10.1016/s0739-7240(02)00151-0.

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48

Gardiner, M. "Mammary gland secretion from a newborn calf." Veterinary Record 120, no. 25 (1987): 603–4. http://dx.doi.org/10.1136/vr.120.25.603.

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Brown Douglas, CG, NR Perkins, KJ Stafford, and DI Hedderley. "Prediction of foaling using mammary secretion constituents." New Zealand Veterinary Journal 50, no. 3 (2002): 99–103. http://dx.doi.org/10.1080/00480169.2002.36290.

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50

Kelleher, Shannon L., Veronica Lopez, Bo Lönnerdal, Jodi Dufner-Beattie, and Glen K. Andrews. "Zip3 (Slc39a3) functions in zinc reuptake from the alveolar lumen in lactating mammary gland." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 297, no. 1 (2009): R194—R201. http://dx.doi.org/10.1152/ajpregu.00162.2009.

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The lactating mammary gland is composed of multiple cell types that tightly coordinate the accumulation, production, and secretion of milk components, including essential metals such as zinc (Zn). Our previous studies in animal and cell models implicated the Zn transporter Zip3 (Slc39a3) in mammary gland Zn acquisition. Herein, we investigated this hypothesis directly by utilizing Zip3-null mice. Our data verify that Zip3 is expressed in secretory mammary cells; however, Zip3 does not play a major role in Zn import from the maternal circulation. Importantly, the primary localization of Zip3 wa
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