Relevant bibliographies by topics / Mannich's bases

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Mannich's bases'

Author: Grafiati
Published: 5 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "Mannich's bases"

1

Layth W. Abdullah, Hanaa K.Saleh, and Mustafa R. Aeyyd. "Synthesis and characterization of novel Mannich's bases incorporated with Ibuprofen an Biginelli Derivatives." Tikrit Journal of Pure Science 22, no. 3 (2023): 79–88. http://dx.doi.org/10.25130/tjps.v22i3.716.

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In this work, a series of novel Mannich's bases incorporated with Ibuprofen core and Biginelli derivatives have been reported. The synthesis process was dependent on linking Ibuprofen hydrazone with Isatin to Biginelli derivatives via methylene group of formaldehyde. The new compounds have been characterized using FT-IR spectroscopy, 1H-NMR spectroscopy and the physical properties.
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A.Yu., Teslenko, Shishlov O.F., Glukhikh V.V., and Yeltsov O.S. "Advanced binders for plywood based on epoxy systems with Mannich's cardanol-containing bases." Systems. Methods. Technologies, no. 1(45) (2020): 85–90. http://dx.doi.org/10.18324/2077-5415-2020-1-85-90.

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Meenakshi, Agrawal. "Synthesis and antimicrobial activity of some novel Mannich's bases of 3- sulfamerazinyl substituted spiro (isatoic anhydrido-4-thiazolidinone) derivatives." Journal of Indian Chemical Society Vol. 92, Jan 2015 (2015): 135–40. https://doi.org/10.5281/zenodo.5606549.

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Department of Chemistry, Teerthanker Mahaveer University, Moradabad-244 102, Uttar Pradesh, India <em>E-mail</em> : meenakshi.agrawal2011@gmail.com <em>Manuscript received online 05 September 2013, accepted 07 August 2014</em> Synthesis of novel 3&acute;-[4&acute;-<em>N</em>-{4-methyl-2-pyrimidinyl}-benzene suphonamido]-spiro-(3H-isatoic anhydride-3,2&acute;- thiazolidin)-1<em>H</em>-2,4&acute;(<em>5H</em>)dione (5) and their Mannich&rsquo;s bases 6(a-g) has been described. Treatment of isatoic anhydride (1) with sulphamerazine (2) yielded 4-[1,2-dihydro-2-oxo-3<em>H</em>-isatoic anhydride-3-y
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Hajiyeva, G. E., E. H. Mammadbayli, S. I. Ibrahimli, and I. A. Jafarov. "NORBORNENE-CONTAINING MANNICH BASES ON THE BASIS OF ALIPHATIC AMINES." Azerbaijan Chemical Journal, no. 3 (2018): 50–56. http://dx.doi.org/10.32737/0005-2531-2018-3-50-56.

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Roth, Hermann J. "„Mannichs molekularsymmetrische Basen” (Zum 50. Todestag von Carl Mannich)." Pharmazie in Unserer Zeit 26, no. 6 (1997): 299–308. http://dx.doi.org/10.1002/pauz.19970260610.

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V., J. Patro, S. Panda C., M. Sahoo B., K. Mishra N., and R. Panda J. "Synthesis and screening for antibacterial, analgesic and anti-inflammatory activity of Mannich bases derived from 1H-indole-2,3-dione." Journal of Indian Chemical Society Vol. 89, Jul 2012 (2012): 913–18. https://doi.org/10.5281/zenodo.5766824.

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Department of Pharmaceutical Chemistry, Roland Institute of Pharmaceutical Sciences, Berhampur-760 010, Orissa, India <em>E-mail</em> : jrpanda77@gmail.com Department of Pharmaceutical Chemistry, Indira Gandhi Institute of Pharmaceutical Sciences, Bhubaneswar, Orissa, India <em>Manuscript received 04 February 2011, revised 16 June 2011, accepted 08 November 2011</em> The reaction of isatin (1<em>H</em>-indole-2,3-dione) with substituted anilines in presence of acetic acid produces Schiff bases. Reaction of the Schiff bases with different secondary amines in presence of formaldehyde yields Mann
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Mardia, Telep El-Sayed. "Synthesis and Antimicrobial Evaluation of Some Nitro-Mannich Bases Derived from β-Nitrostyrene". Open Journal of Chemistry 1, № 1 (2015): 013–16. https://doi.org/10.17352/ojc.000003.

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The present work focused on exploring the reactivity of &beta;-nitrostyrene towards Mannich reaction with different approaches. The synthesized nitro-Mannich bases were tested as antimicrobial agents that showed high activity against both gram positive and gram negative bacteria.
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Hajiyeva, G. E. "SYNTHESIS OF MANNICH BASES BASED ON NORBORNENYLMETHANOL, CYCLIC AMINES AND BENZALDEHYDE AND THEIR ANTIMICROBIAL ACTIVITY." Azerbaijan Chemical Journal, no. 3 (October 10, 2019): 68–74. http://dx.doi.org/10.32737/0005-2531-2019-3-68-74.

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Abdel, Karim M., I. Hala, and M. Khalid. "Synthesis and Antimicrobial Activity of Phenol-derived Mannich Bases." Pharmaceutical and Chemical Journal 4, no. 6 (2017): 107–13. https://doi.org/10.5281/zenodo.13888833.

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Using p-acetamidophenol as an active hydrogen component, two Mannich bases: N,N-[(<strong>5-</strong>acatamido-2-hydroxy)benzyl]ethylamine(I)<strong> </strong>and N-[(5-acatamido-2-hydroxy)benzyl]ethylamine(II) were synthesized via a general synthesis protocol. .The structures of the target molecules were elucidated by a combination of spectral techniques (UV, IR, <sup>1</sup>H NMR and MS). The Mannich bases were evaluated for their antimicrobial activity against seven standard human pathogens. Compounds I and II showed excellent activity against <em>Escherichia coli </em>at 10 and 20mg/ml. Fu
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Panda, Jnyanaranjan. "Synthesis and Biological Evaluation of Some Isatin-based Mannich Bases." International Journal of Pharmaceutical Sciences and Nanotechnology 5, no. 4 (2013): 1841–46. http://dx.doi.org/10.37285/ijpsn.2012.5.4.3.

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&#x0D; In this study, a series of isatin-based Mannich bases were prepared and their biological activity was evaluated. Schiff bases of isatin were synthesized by condensation of the keto group of isatin with different aromatic primary amines. The N-Mannich bases of the above Schiff bases were synthesized by reaction of the acidic imino group of isatin with formaldehyde and secondary amine. The chemical structures of the title compounds have been confirmed and elucidated by means of their physical and spectral data respectively. The compounds were tested for their possible antibacterial, analg
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Dissertations / Theses on the topic "Mannich's bases"

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Roche, Maxime. "Etude des 3,4-Dihydro-2H-1, 3-Benzoxzazines : Réactivité - Polymérisation." Besançon, 1989. http://www.theses.fr/1989BESA2039.

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Ce travail consacre a l'etude de la reactivite des 3,4-dihydro-2h-1,3-benzoxazines rend compte de leur aptitude a la polymerisation. Divers composes de ce type, synthetises a partir de phenols, formaldehyde et amines primaires ont ete etudies en spectrometrie de masse, par rmn #1h et #1#3c et par spectroscopie ir. La reaction avec les phenols qui procede par un mecanisme avec ouverture de cycle peut etre consideree comme l'etape d'amorcage d'une polymerisation. Ainsi nous avons etudie, dans un premier temps, la polymerisation de ces benzoxazines amorcee avec des phenols, la mise en evidence d'
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Hermange, Philippe. "Réaction de Mannich vinylogue diastéréosélective entre des sels d’isoquinolinium et des silyloxyfuranesApplication à la synthèse de nouveaux ligands du récepteur GABA-A et à des analogues de l’émétine." Paris 11, 2009. http://www.theses.fr/2009PA112200.

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En partant d’une observation expérimentale révélant la haute diastéréosélectivité obtenue lors de la réaction de Mannich vinylogue entre un sel d’isoquinolinium et un dérivé silyloxyfurane, plusieurs axes de recherche ont été développés au cours de cette thèse. Tout d’abord, une étude méthodologique a permis de généraliser la réaction (rendements et excès diastéréoisomériques supérieurs à 80%). Après la mise au point d’un protocole à trois composantes, la réaction a pu être étendue par exemple à la formation de centres quaternaires ou à l’utilisation de silyloxypyrroles. Le rôle prépondérant d
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Trossini, Gustavo Henrique Goulart. "Antichagásicos potenciais: síntese de bases de Mannich do hidroximetilnitrofural." Universidade de São Paulo, 2004. http://www.teses.usp.br/teses/disponiveis/9/9138/tde-28102010-104123/.

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A doença de Chagas é endemia que afeta grande parte da América Latina. Estima-se que de 18 a 20 milhões de pessoas estejam infectadas pelo parasita causador da doença e que ocorram, aproximadamente, 50.000 mortes relacionadas à doença de Chagas por ano, nos 21 países da área endêmica. O arsenal terapêutico atualmente usado contra a parasitose, constituído por apenas dois fármacos, é insuficiente, considerando-se, também, que ambos não apresentam ação adequada na fase crônica da doença. Em razão de se tratar de parasitose que acomete apenas países em desenvolvimento, o interesse na pesquisa de
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Ghaib, Amar. "Pharmacomodulation autour du squelette octahydropyrimido[3,4-a]-s-triazines : introduction de restes alkyles de lipophilie croissante." Rouen, 2001. http://www.theses.fr/2001ROUE03NR.

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L'iminodiméthylation de six monoalkyl ou dialkyl 5-aminopyrimidine-l,3-diones par différentes amines primaires fait l'objet de cette étude. La préparation de ces synthons est réalisée à partir de cyanacétates d'éthyles, préalablement alkylés en position 2, qui réagissent avec l'urée, en milieu alcalin. L'alkylation de méthylènes fortement activés qui sont situés entre une fonction nitrile et un groupement ester, en milieu alcalin, conduit à un mélange de dérivés non alkylé, monoalkylé et dialkylé. Il s'est avéré nécessaire d'utiliser les différences de solubilité des sels de ces composés pour
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Kandepu, Narayana Murthi. "Mannich bases of chalcones and cyclohexanones as candidate cytotoxic agents." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0035/NQ63974.pdf.

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Al-Sarabi, Alaeddin. "Application de la réaction de Mannich intramoléculaire à la synthèse d'hétérocycles azotés." Clermont-Ferrand 2, 2004. http://www.theses.fr/2004CLF21491.

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Nous avons préparé par une réaction de Mannich intramoléculaire impliquant divers aldéhydes et des bétâ-aminocétones ceto-protégées : L'(-+)-indolizidine 209D en douze étapes à partir du 4-chlorobutanol. L'(-+)-allosédridine en neuf étapes à partir du 5-chloropentanol. Par la même voie, isoindolopipéridines polycycliques ont pu être obtenues en une seule étape. Nous avons pu montrer que cette réaction était applicable en synthèse asymétrique. La synthèse que nous avons effectuée est intéressante comparée aux autres voies de synthèse proposées dans la littérature en termes de simplicité. Elle n
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Ward, Nathan Andrew. "Resurrection of Organophosphorus-Aged Acetylcholinesterase via Mannich Bases Derived from Proline." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1565714137331736.

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Thomas, Anne. "Synthèse de dérivés pipéridiniques sur support solide." Clermont-Ferrand 2, 2004. http://www.theses.fr/2004CLF21499.

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Ce travail décrit une nouvelle méthode d'accès à des composés pipéridiniques. Une réaction intramoléculaire de type Mannich, impliquant un aldéhyde et une bétâ-aminocétone protégée, permet la création du cycle pipéridinique. La transposition de cette méthode développée en solution est à l'origine d'un projet délaboration de librairies combinatoires : deux méthodes d'immobilisation de ces squelettes pipéridiniques sur support solide ont été entreprises. La première repose sur l'accrochage de pipéridinones par la fonction cétone via une amination réductrice avec une amine supportée. Un second po
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TEDLAOUTI, FATIHA. "Pharmacologie antimalarique et trypanocide de derives thiopheniques, de bases de mannich et de saponosides d'hedera helix l. , calendula arvensis l. Et de sapendus mukurosi l." Aix-Marseille 2, 1991. http://www.theses.fr/1991AIX22957.

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Jean, Alexandre. "Synthèse organocatalytique d’hétérocycles azotés et oxygénés." Caen, 2013. http://www.theses.fr/2013CAEN2057.

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Les pyrrolidines chirales sont d’importants motifs moléculaires pouvant trouver des applications en tant qu’organocatalyseurs, comme ligands pour la catalyse organométallique ou encore en tant qu’intermédiaires de synthèse de produits naturels ou d’intérêts thérapeutiques. Une méthode de synthèse rapide et efficace, organocatalytique, a été développée pour la formation de pyrrolidines 1,2,3,5-tétra-substituées à partir d’hydroxyalcynes facilement préparés. Une réaction de Mannich asymétrique combinée à une réaction d’hydroamination intramoléculaire d’alcynes en conditions acides nous a permis
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Books on the topic "Mannich's bases"

1

Challiner, John Francis. Photochemistry of imide mannich bases. The Polytechnic, Wolverhampton, Department of Physical Sciences, 1985.

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Luigi, Angiolini, ed. Mannich bases: Chemistry and uses. CRC Press, 1994.

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Book chapters on the topic "Mannich's bases"

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Colacio, Enrique. "Mannich Base Ligands as Versatile Platforms for SMMs." In Topics in Organometallic Chemistry. Springer International Publishing, 2018. http://dx.doi.org/10.1007/3418_2018_4.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of copper(II) complex with Mannich base, N-(morpholinobenzyl)-benzamide." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 4. Springer Berlin Heidelberg, 2021. http://dx.doi.org/10.1007/978-3-662-62474-6_107.

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Seeni Mubarak, M., R. Kathirvel, M. Sathyanarayanan, and S. Mohamed Rabeek. "Some Novel Mannich Bases-Synthesis, Crystal Structure, Docking Studies, Anti-microbial Activity, and Cytotoxicity." In Springer Proceedings in Physics. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-44890-9_56.

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Koll, Aleksander, and Peter Wolschann. "Mannich Bases as Model Compounds for Intramolecular Hydrogen Bonding II [1] Structure and Properties in Solution." In Hydrogen Bond Research. Springer Vienna, 1999. http://dx.doi.org/10.1007/978-3-7091-6419-8_3.

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Cui, Shengchao, Guangzheng Wang, Shu Liu, Xintong Yan, and Ming Fan. "Synthesis and Property Analysis of a Novel Epoxy Composite Curing Agent Based on Soft Soil Curing." In Lecture Notes in Civil Engineering. Springer Nature Singapore, 2024. https://doi.org/10.1007/978-981-97-6238-5_46.

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AbstractTo meet the demand for shore-based engineering, engineering rescue and traffic emergency support in different complex conditions, a new low-temperature fast solidifier for epoxy resin was synthesized by Mannich reaction using thiourea, polyamine, formaldehyde, phenol and benzyl alcohol. The performance of the curing agent was investigated based on raw material ratio, reaction temperature and reaction time. Moreover, the curing time, amine value, viscosity and infrared spectrum were tested. It was compounded with other highly active curing agents and resins. The compressive strength of
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Pardasani, R. T., and P. Pardasani. "Magnetic properties of mixed ligand iron(III) complex with cyanide, nitrosyl and Mannich base." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 6. Springer Berlin Heidelberg, 2022. http://dx.doi.org/10.1007/978-3-662-65056-1_104.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of mixed ligand iron(III) complex with cyanide, nitrosyl and Mannich base." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 6. Springer Berlin Heidelberg, 2022. http://dx.doi.org/10.1007/978-3-662-65056-1_105.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of mixed ligand iron(III) complex with cyanate, nitrosyl and Mannich base." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 6. Springer Berlin Heidelberg, 2022. http://dx.doi.org/10.1007/978-3-662-65056-1_102.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of mixed ligand iron(III) complex with azide, nitrosyl and Mannich base." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 6. Springer Berlin Heidelberg, 2022. http://dx.doi.org/10.1007/978-3-662-65056-1_100.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of mixed ligand iron(III) complex with cyanate, nitrosyl and Mannich base." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 6. Springer Berlin Heidelberg, 2022. http://dx.doi.org/10.1007/978-3-662-65056-1_103.

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Conference papers on the topic "Mannich's bases"

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Figovsky, Oleg L., and Dmitry A. Beilin. "Crack- Resistant and Anticorrosive Coatings Based on Vulcanized Water Dispersion of Chlorine-Sulfo-Polyethylene." In CORROSION 2010. NACE International, 2010. https://doi.org/10.5006/c2010-10036.

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Abstract Advanced crack resistant coatings based on water dispersion of chlorine-sulfo-polyethylene (CSPE,) vulcanized by Mannich alkalis (MA) water solution were obtained. Application of MA as a CSPE structure component makes it possible to produce a vulcanized net of saturated polymer, and thus to receive ecologically safe impenetrable crack resistant coatings of any substrata (concrete, metal, plastic, etc.). The coatings can be applied in aircraft, automotive, shipbuilding, paint and varnish industries, civil engineering, etc. as a corrosion-resistant material. The optimal coating composit
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Xu, Limin, Tao Chen, Ming Han, and Mohammed Bataweel. "Corrosion Inhibition of Carbon Steel in Carbonate Acidizing at Elevated Temperature." In CONFERENCE 2022. AMPP, 2022. https://doi.org/10.5006/c2022-17562.

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Abstract This paper presents an investigation on the performance of corrosion inhibitors in reducing corrosion loss of N80 steel coupons at high temperature in 15 wt.% and 28 wt.% HCl solutions. This work studied the effect of temperature and acid concentration on corrosion inhibitor performance and provided an efficient corrosion inhibitor for application at elevated temperature of 120°C. Five corrosion inhibitors including Mannich base derivatives and pyridine quaternary ammonium salt were selected. The corrosion rates of N80 steel in concentrated HCl solution with and without corrosion inhi
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He, Meng, Haoyuan Kang, Juanbo Liu, Sheng Chen, Xueru Gong, and Li Sun. "Development of Inhibitor for Corrosion Protection of Condensate Stripping Process in Industrial Coal Gasification Unit." In ASME 2021 Pressure Vessels & Piping Conference. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/pvp2021-61869.

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Abstract The condensate involving HS-, CO32−, Cl− and NH4+ usually causes severe corrosion of 20 steel in condensate stripping process of industrial coal gasification unit. The corrosion can easily lead to failure of pipe fittings and vessels, and result in economic losses and personal injury. To protect industrial coal gasification unit against corrosion, five inhibitors including imidazoline, imidazoline amide, mannich base quaternary ammonium salt, pyridine, and sodium molybdate are investigated with experiment of linear polarization curve, polarization curve, electrochemical impedance spec
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Farj, Alaa Sarhan, and Khalida F. Al-Azawi. "Synthesis, characterization and antimicrobial activity of novel Mannich bases." In TECHNOLOGIES AND MATERIALS FOR RENEWABLE ENERGY, ENVIRONMENT AND SUSTAINABILITY: TMREES21Gr. AIP Publishing, 2022. http://dx.doi.org/10.1063/5.0092314.

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Verigina, Anastasiia Alexseevna, Tatiana Sergeevna Stepanova, and Pavel Iosifovich Pinko. "PREPARATION OF ALKYLTHIOMETHYLATED DERIVATIVES OF 2,4-DI-TERT-BUTYLPHENOL AND PRELIMINARY ASSESSMENT OF THEIR ANTIOXIDANT ACTIVITY." In IX Международная научно-практическая конференция "Инновационные аспекты развития науки и техники". KDU, Moscow, 2021. http://dx.doi.org/10.31453/kdu.ru.978-5-7913-1190-0-2021-6-14.

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This article discusses a method for the preparation of alkylthiomethyl derivatives of 2,4-di-tert-butylphenol through the interaction of the obtained Mannich bases with aliphatic thiols of various structures, as well as a preliminary assessment of the antioxidant activity by anodic voltammetry.
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Funar-Timofei, Simona, Ana Borota, Alina Bora, Sorin Avram, and Daniela Ionescu. "QSAR MODELING ON FUNGICIDAL ACTIVITY OF MANNICH BASES." In The 19th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2015. http://dx.doi.org/10.3390/ecsoc-19-e005.

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Allochio Filho, J. F., L. L. Roldi, R. Fiorot, et al. "Synthesis and in vitro antifungal activity of new Mannich bases derived from 2-hydroxy-1,4-naphthoquinone (Lawsone)." In 15th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_2013916122532.

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Rodríguez, Laura, Elena Viqueira, Oscar Souto, and Antonio Sousa-Pedrares. "Synthesis and characterization of new Mannich base ligand. Structure of N, N-bis-(4,5-dimethyl-2-hydroxybenzyl)-N(2-pyridylmethyl)amine." In The 10th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2006. http://dx.doi.org/10.3390/ecsoc-10-01414.

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Verdes, Anastasia, Elena Gorincioi, Lucian Lupascu, Gheorghe Duca, and Fliur Macaev. "Targeting the bioactive dihydropyrimidines by ecofriendly procedure of biginelli reaction: study case of monastrol." In Scientific seminar with international participation "New frontiers in natural product chemistry". Institute of Chemistry, Republic of Moldova, 2023. http://dx.doi.org/10.19261/nfnpc.2023.ab24.

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Biologically active compounds decorated with dihydropyridine moiety are counted amongst the numerous broad-spectrum therapeutic agents that explain the increasing role of this scaffold in rational drug design [1]. The Biginelli reaction is a multicomponent reaction of aldehyde, (thio)urea, and ß-ketoester, involving Mannich reaction in the first step, which produces multifunctionalized 3,4-dihydropyrimidin-2-(1H)-ones and related heterocyclic compounds [2]. The attractiveness of this acid-catalyzed one-pot condensation reaction lies in the simplicity of grafting the substituent into the struct
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