Academic literature on the topic 'Mass spectrometry imaging'

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Journal articles on the topic "Mass spectrometry imaging"

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Heeren, Ron M. A., and Jonathan V. Sweedler. "Imaging mass spectrometry imaging." International Journal of Mass Spectrometry 260, no. 2-3 (2007): 89. http://dx.doi.org/10.1016/j.ijms.2006.11.016.

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NAITO, Yasuhide. "Imaging Mass Spectrometry." Journal of the Mass Spectrometry Society of Japan 55, no. 1 (2007): 39. http://dx.doi.org/10.5702/massspec.55.39.

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Nirasawa, Takashi, Toshiji Kudo, and Takaya Satoh. "Imaging mass spectrometry." Japanese Journal of Pesticide Science 42, no. 1 (2017): 216–22. http://dx.doi.org/10.1584/jpestics.w17-51.

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Shimma, Shuichi. "Mass Spectrometry Imaging." Mass Spectrometry 11, no. 1 (2022): A0102. http://dx.doi.org/10.5702/massspectrometry.a0102.

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Setou, Mitsutoshi. "Imaging Mass Spectrometry." YAKUGAKU ZASSHI 132, no. 4 (2012): 499–506. http://dx.doi.org/10.1248/yakushi.132.499.

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Smeal, Joseph, and Charles L. Wilkins. "Imaging Mass Spectrometry." Applied Spectroscopy Reviews 46, no. 6 (2011): 425–39. http://dx.doi.org/10.1080/05704928.2011.570834.

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McDonnell, Liam A., and Ron M. A. Heeren. "Imaging mass spectrometry." Mass Spectrometry Reviews 26, no. 4 (2007): 606–43. http://dx.doi.org/10.1002/mas.20124.

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Porta Siegel, Tiffany, and Shane R. Ellis. "Mass spectrometry imaging 2.0." Analytical and Bioanalytical Chemistry 413, no. 10 (2021): 2597–98. http://dx.doi.org/10.1007/s00216-021-03293-9.

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Blaschke, Calvin R. K., Colin T. McDowell, Alyson P. Black, Anand S. Mehta, Peggi M. Angel, and Richard R. Drake. "Glycan Imaging Mass Spectrometry." Clinics in Laboratory Medicine 41, no. 2 (2021): 247–66. http://dx.doi.org/10.1016/j.cll.2021.03.005.

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Franck, Julien, Karim Arafah, Mohamed Elayed, et al. "MALDI Imaging Mass Spectrometry." Molecular & Cellular Proteomics 8, no. 9 (2009): 2023–33. http://dx.doi.org/10.1074/mcp.r800016-mcp200.

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Dissertations / Theses on the topic "Mass spectrometry imaging"

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Yuen, Wei Hao. "Ion imaging mass spectrometry." Thesis, University of Oxford, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.564395.

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This work investigates the applicability of fast detectors to the technique of microscope-mode imaging mass spectrometry. By ionising analyte from a large area of the sample, and projecting the desorbed ions by the use of ion optics through a time-of-flight mass spectrometer onto a two- dimensional detector, time- (and hence mass-) dependent distributions of ions may be imaged. To date, this method of imaging mass spectrometry has been limited by the ability to image only one mass window of interest per experimental cycle, limiting throughput and processing speed. Thus, the alternative micropr
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Cobice, Diego Federico. "Mass spectrometry imaging of steroids." Thesis, University of Edinburgh, 2015. http://hdl.handle.net/1842/21032.

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Glucocorticoids are steroid hormones involved in the stress response, with a well-established role in promoting cardiovascular risk factors including obesity and diabetes. The focus of glucocorticoid research has shifted from understanding control of blood levels, to understanding the factors that control tissue steroid concentrations available for receptor activation; it is disruption of these tissue-specific factors that has emerged as underpinning pathophysiological mechanisms in cardiovascular risk, and revealed potential therapeutic targets. However, the field is hampered by the inability
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Palmer, Andrew D. "Information processing for mass spectrometry imaging." Thesis, University of Birmingham, 2014. http://etheses.bham.ac.uk//id/eprint/5472/.

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Mass Spectrometry Imaging (MSI) is a sensitive analytical tool for detecting and spatially localising thousands of ions generated across intact tissue samples. The datasets produced by MSI are large both in the number of measurements collected and the total data volume, which effectively prohibits manual analysis and interpretation. However, these datasets can provide insights into tissue composition and variation, and can help identify markers of health and disease, so the development of computational methods are required to aid their interpretation. To address the challenges of high dimensio
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Stryffeler, Rachel Bennett. "New analytical approaches for mass spectrometry imaging." Diss., Georgia Institute of Technology, 2015. http://hdl.handle.net/1853/54892.

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Chemical imaging by mass spectrometry is a powerful approach by which to map spatial distributions of molecules to better understand their function in the system of interest. Over the last thirty years, MSI has evolved into a very powerful analytical tool for the investigation of chemically-complex samples including biological tissues, catalytic surfaces and thin layer chromatography plates, among many others. The work in this dissertation aimed to characterize existing MSI methods, while also developing novel instrumentation able to overcome the challenges found in a variety of applications.
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Fornai, L. "Molecular Imaging of the heart by mass spectrometry." Doctoral thesis, Università degli studi di Padova, 2011. http://hdl.handle.net/11577/3421675.

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BACKGROUND Cardiovascular diseases are the world’s number one death cause, accounting for 17.1 million deaths a year. There is still much unknown about cardiovascular diseases and their physiological underlying mechanism. Understanding the nature of complex biological processes occurring in both healthy and diseased heart tissue requires identifying the compounds involved and determining where they are located. Summary METHODS We have investigated a complementary mass spectrometry imaging (MSI) approach using matrix-assisted laser desorption/ionization (MALDI) and secondary ion mass spe
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Jung, Seokwon. "Surface characterization of biomass by imaging mass spectrometry." Diss., Georgia Institute of Technology, 2012. http://hdl.handle.net/1853/45906.

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Lignocellulosic biomass (e.g., non food-based agricultural resides and forestry wastes) has recently been promoted for use as a source of bioethanol instead of food-based materials (e.g., corn and sugar cane), however to fully realize these benefits an improved understanding of lignocellulosic recalcitrance must be developed. The primary goal of this thesis is to gain fundamental knowledge about the surface of the plant cell wall, which is to be integrated into understanding biomass recalcitrance. Imaging mass spectrometry by TOF-SIMS and MALDI-IMS is applied to understand detailed spatial a
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Henderson, Fiona. "Mass spectrometry imaging of lipid profiles in disease." Thesis, University of Manchester, 2017. https://www.research.manchester.ac.uk/portal/en/theses/mass-spectrometry-imaging-of-lipid-profiles-in-disease(f1b202b1-2a6e-416e-ab81-321ef4f0e24d).html.

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It is well established that lipids play an important role in diseases such as non-alcoholic fatty liver disease and cardiovascular diseases. However, in the past decade, it has come to light that lipids may be important in other diseases; particularly in cancer and neurological disorders. Here, lipid metabolism has been investigated using pre-clinical cancer models for melanoma, glioma, non-small-cell lung cancer and colorectal cancer. The role of lipids in the recovery post-stroke has also been studied. Mass spectrometry imaging offers an ideal tool to study lipids in tissue ex-vivo. Lipids i
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Guo, Ang. "Improving the performance of microscope mass spectrometry imaging." Thesis, University of Oxford, 2018. http://ora.ox.ac.uk/objects/uuid:aa94a7f6-00ee-4b56-ba65-f6946799d5f2.

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Mass spectrometry imaging (MSI) is a powerful tool that provides mass-specific surface images with micron or sub-micron spatial resolutions. In a microscope MSI experiment, large sample surfaces are illuminated with a defocused laser or primary ion beam, enabling all surface molecules to be desorbed and ionised simultaneously before being electrostatically projected onto a position-sensitive imaging detector at the end of a time-of-flight mass analyser. Traditionally only the image of one mass-to-charge ratio can be obtained in a single acquisition, which limits its applicability. However, the
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Nakata, Yoshihiko. "Imaging Mass Spectrometry with MeV Heavy Ion Beams." 京都大学 (Kyoto University), 2009. http://hdl.handle.net/2433/124537.

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Hulme, Heather E. "Mass spectrometry imaging to investigate host-microbe interactions." Thesis, University of Glasgow, 2018. http://theses.gla.ac.uk/8930/.

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Mass spectrometry imaging (MSI) is a powerful tool for mapping the spatial distribution and relative abundance of molecules across a sample surface. The distribution of proteins, metabolites, lipids and drugs can be determined and unlike other molecular imaging techniques, such as immunohistochemistry (IHC), MSI is completely label-free. Therefore, this technique does not require prior knowledge of the molecule to be imaged and thousands of molecules can be imaged at once. This is particularly useful for untargeted imaging, to discover molecules which are important for a certain condition. For
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Books on the topic "Mass spectrometry imaging"

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Cole, Laura M., ed. Imaging Mass Spectrometry. Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-7051-3.

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Rubakhin, Stanislav S., and Jonathan V. Sweedler, eds. Mass Spectrometry Imaging. Humana Press, 2010. http://dx.doi.org/10.1007/978-1-60761-746-4.

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Setou, Mitsutoshi, ed. Imaging Mass Spectrometry. Springer Japan, 2010. http://dx.doi.org/10.1007/978-4-431-09425-8.

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Cole, Laura M., and Malcolm R. Clench, eds. Imaging Mass Spectrometry. Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-3319-9.

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Porta Siegel, Tiffany, ed. MALDI Mass Spectrometry Imaging. Royal Society of Chemistry, 2021. http://dx.doi.org/10.1039/9781839165191.

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Lee, Young-Jin, ed. Mass Spectrometry Imaging of Small Molecules. Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2030-4.

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He, Lin, ed. Mass Spectrometry Imaging of Small Molecules. Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-1357-2.

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Lin, He. Mass spectrometry imaging of small molecules. Humana Press, 2014.

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Lindon, John C. Encyclopedia of spectroscopy and spectrometry. Academic Press, 2000.

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S, Suri Jasjit, and Farag Aly A, eds. Deformable models. Springer, 2007.

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Book chapters on the topic "Mass spectrometry imaging"

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Szynkowska, Małgorzata Iwona. "Imaging of Small Molecules." In Mass Spectrometry. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470395813.ch13.

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Morgan, Michael M., MacDonald J. Christie, Thomas Steckler, et al. "Mass Spectrometry Imaging." In Encyclopedia of Psychopharmacology. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-68706-1_4342.

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Carroll, Marilyn E., Peter A. Santi, Joseph Zohar, et al. "Imaging Mass Spectrometry." In Encyclopedia of Psychopharmacology. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-68706-1_1552.

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Reyzer, Michelle L., and Richard M. Caprioli. "Imaging Mass Spectrometry." In NATO Science for Peace and Security Series A: Chemistry and Biology. Springer Netherlands, 2010. http://dx.doi.org/10.1007/978-90-481-9815-3_17.

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Setou, Mitsutoshi. "IMS as an Historical Innovation." In Imaging Mass Spectrometry. Springer Japan, 2010. http://dx.doi.org/10.1007/978-4-431-09425-8_1.

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Sugiura, Yuki, and Mitsutoshi Setou. "Statistical Procedure for IMS Data Analysis." In Imaging Mass Spectrometry. Springer Japan, 2010. http://dx.doi.org/10.1007/978-4-431-09425-8_10.

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Zaima, Nobuhiro, and Mitsutoshi Setou. "Statistical Analysis of IMS Dataset with ClinproTool Software." In Imaging Mass Spectrometry. Springer Japan, 2010. http://dx.doi.org/10.1007/978-4-431-09425-8_11.

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Yang, Hyun Jeong, Yuki Sugiura, Koji Ikegami, and Mitsutoshi Setou. "Imaging of Cultured Cells by Mass Spectrometry." In Imaging Mass Spectrometry. Springer Japan, 2010. http://dx.doi.org/10.1007/978-4-431-09425-8_12.

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Goto-Inoue, Naoko, Takao Taki, and Mitsutoshi Setou. "TLC-Blot-MALDI-IMS." In Imaging Mass Spectrometry. Springer Japan, 2010. http://dx.doi.org/10.1007/978-4-431-09425-8_13.

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Kokaji, Tetsuo. "Applied Biosystems." In Imaging Mass Spectrometry. Springer Japan, 2010. http://dx.doi.org/10.1007/978-4-431-09425-8_14.

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Conference papers on the topic "Mass spectrometry imaging"

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Warren, Jade, Amoon Jamzad, Tamara Jamaspishvili, et al. "Towards Improving Surgical Margins in Tumour Resection Using Mass Spectrometry Imaging." In 2024 IEEE Canadian Conference on Electrical and Computer Engineering (CCECE). IEEE, 2024. http://dx.doi.org/10.1109/ccece59415.2024.10667088.

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Luna, José Marcio, Hani Nakhoul, Cody Weimholt, et al. "A Pipeline for Histopathology Analysis of Prostate Cancer Guided by Mass Spectrometry Imaging." In 2024 IEEE International Symposium on Biomedical Imaging (ISBI). IEEE, 2024. http://dx.doi.org/10.1109/isbi56570.2024.10635223.

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Wainwright, Alexander, Khaled Madhoun, Pei Su, et al. "Application of nanosecond mid-infrared lasers in mass spectrometry imaging of intact proteins." In Optical Interactions with Tissue and Cells XXXVI, edited by Joel N. Bixler, Norbert Linz, and Alex J. Walsh. SPIE, 2025. https://doi.org/10.1117/12.3039292.

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Belsey, Natalie, Dimitrios Tsikritsis, Camilla Dondi, Jean-Luc Vorng, Alex Dexter, and Mike Shaw. "Combining vibrational and fluorescence microscopies with mass spectrometry imaging for visualization of drug delivery." In Visualizing and Quantifying Drug Distribution in Tissue IX, edited by Conor L. Evans and Kin Foong Chan. SPIE, 2025. https://doi.org/10.1117/12.3043629.

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Sarycheva, Anastasia, Anton Grigoryev, Evgeny N. Nikolaev, and Yury Kostyukevich. "Robust Simulation Of Imaging Mass Spectrometry Data." In 35th ECMS International Conference on Modelling and Simulation. ECMS, 2021. http://dx.doi.org/10.7148/2021-0192.

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Mass spectrometry imaging (MSI) with high resolution in mass and space is an analytical method that produces distributions of ions on a sample surface. The algorithms for preprocessing and analysis of the raw data acquired from a mass spectrometer should be evaluated. To do that, the ion composition at every point of the sample should be known. This is possible via the employment of a simulated MSI dataset. In this work, we suggest a pipeline for a robust simulation of MSI datasets that resemble real data with an option to simulate the spectra acquired from any mass spectrometry instrument thr
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Kawai, Yosuke, Kentaro Terada, Toshinobu Hondo, et al. "Development of a Secondary Neutral Mass Spectrometer for Submicron Imaging Mass Spectrometry." In Proceedings of the 15th International Symposium on Origin of Matter and Evolution of Galaxies (OMEG15). Journal of the Physical Society of Japan, 2020. http://dx.doi.org/10.7566/jpscp.31.011065.

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Hazama, Hisanao, Jun Aoki, Hirofumi Nagao, et al. "Stigmatic imaging mass spectrometry using a multi-turn time-of-flight mass spectrometer." In The Pacific Rim Conference on Lasers and Electro-Optics (CLEO/PACIFIC RIM). IEEE, 2009. http://dx.doi.org/10.1109/cleopr.2009.5292164.

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Muir, E. R., I. J. Ndiour, N. A. Le Goasduff, et al. "Multivariate Analysis of Imaging Mass Spectrometry Data." In 7th IEEE International Conference on Bioinformatics and Bioengineering. IEEE, 2007. http://dx.doi.org/10.1109/bibe.2007.4375603.

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Coello, Yves, A. Daniel Jones, Tissa C. Gunaratne, and Marcos Dantus. "Atmospheric Pressure Femtosecond Laser Imaging Mass Spectrometry." In Laser Applications to Chemical, Security and Environmental Analysis. OSA, 2010. http://dx.doi.org/10.1364/lacsea.2010.ltua2.

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Coello, Yves, A. Daniel Jones, Tissa C. Gunaratne, and Marcos Dantus. "Atmospheric Pressure Femtosecond Laser Imaging Mass Spectrometry." In International Conference on Ultrafast Phenomena. OSA, 2010. http://dx.doi.org/10.1364/up.2010.wc5.

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Reports on the topic "Mass spectrometry imaging"

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Moore, Jerome, and Andrew Moore. Ion Mobility – Mass Spectrometry Rapid Imaging of Special Nuclear Materials. Office of Scientific and Technical Information (OSTI), 2023. http://dx.doi.org/10.2172/1995985.

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Feenstra, Adam D. Technological Development of High-Performance MALDI Mass Spectrometry Imaging for the Study of Metabolic Biology. Office of Scientific and Technical Information (OSTI), 2016. http://dx.doi.org/10.2172/1409181.

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Korte, Andrew R. Development of matrix-assisted laser desorption ionization-mass spectrometry imaging (MALDI-MSI) for plant metabolite analysis. Office of Scientific and Technical Information (OSTI), 2014. http://dx.doi.org/10.2172/1226566.

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McVey, Patrick. Direct analysis of solid samples by electrospray laser desorption ionization mass spectrometry imaging: From plants to pharmaceuticals. Office of Scientific and Technical Information (OSTI), 2018. http://dx.doi.org/10.2172/1505182.

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Maharrey, Sean P., Aaron M. Highley, Richard, Jr Behrens, and Deneille Wiese-Smith. Final LDRD report : development of sample preparation methods for ChIPMA-based imaging mass spectrometry of tissue samples. Office of Scientific and Technical Information (OSTI), 2007. http://dx.doi.org/10.2172/966248.

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Cha, Sangwon. Laser desorption/ionization mass spectrometry for direct profiling and imaging of small molecules from raw biological materials. Office of Scientific and Technical Information (OSTI), 2008. http://dx.doi.org/10.2172/976267.

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Yagnik, Gargey B. Nanoparticle-assisted laser desorption/ionization mass spectrometry: Novel sample preparation methods and nanoparticle screening for plant metabolite imaging. Office of Scientific and Technical Information (OSTI), 2016. http://dx.doi.org/10.2172/1342543.

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Weber, P., and J. Pett-Ridge. Performance Metric Q4: Report on the use of imaging and mass spectrometry-based capabilities to describe microbiome interactions. Office of Scientific and Technical Information (OSTI), 2021. http://dx.doi.org/10.2172/1823697.

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Cooke, E., M. Hayes, M. Romanchikova, et al. Acquisition & management of high content screening, light-sheet microscopy and mass spectrometry imaging data at AstraZeneca, GlaxoSmithKline and NPL. National Physical Laboratory, 2020. http://dx.doi.org/10.47120/npl.mn25.

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Cooke, E., M. Hayes, M. Romanchikova, et al. Acquisition & management of high content screening, light-sheet microscopy and mass spectrometry imaging data at AstraZeneca, GlaxoSmithKline and NPL. National Physical Laboratory, 2020. http://dx.doi.org/10.47120/npl.ms25.

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