Relevant bibliographies by topics / Mcy genes / Dissertations / Theses
To see the other types of publications on this topic, follow the link: Mcy genes.

Dissertations / Theses on the topic 'Mcy genes'

Author: Grafiati
Published: 4 June 2021
Last updated: 2 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 dissertations / theses for your research on the topic 'Mcy genes.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.

1

Crespim, Elaine. "Identificação e sequenciamento de genes envolvidos na biossíntese de microcistinas e saxitoxinas na cianobactéria Microcystis aeruginosa SPC777." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/64/64133/tde-22052013-112756/.

Full text
Abstract:
As toxinas produzidas por cianobactérias em ecossistemas aquáticos de superfície utilizados para abastecimento público constituem uma preocupação mundial, com casos de intoxicação relatados em diversos países.Sérios problemas de saúde e até mesmo óbito podem ocorrer como consequência dessas intoxicações. Em ambientes de água doce eutrofizados, florações de espécies de Microcystis são frequentemente observadas e, devido à sua ampla distribuição geográfica e capacidade de produzir toxinas, este é um dos gêneros de cianobactérias mais extensivamente estudados. Microcystis spp. são conhecidas pela
APA, Harvard, Vancouver, ISO, and other styles
2

Peres, Raquel Mary Rodrigues 1983. "Instabilidade genômica em neoplasias malignas da mama em função da concentração de alumínio intracelular : Genomic instability association with intracellular aluminum concentration in breast tumors." [s.n.], 2013. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310522.

Full text
Abstract:
Orientador: Luis Otavio Zanatta Sarian<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-11-07T13:37:40Z (GMT). No. of bitstreams: 1 Peres_RaquelMaryRodrigues_D.pdf: 3497486 bytes, checksum: c509c5d08807f1a5bcd1b918eaf7d09d (MD5) Previous issue date: 2013<br>Resumo: Introdução: A hipótese de que os efeitos do alumínio em células humanas podem ter implicações clínicas tem sido levantada há algum tempo, especialmente no que concerne ao câncer de mama. As evidências laboratoriais mostrando altos níveis de alumínio nos teci
APA, Harvard, Vancouver, ISO, and other styles
3

Goldman, Jacki P. "Regulated accessibility of variable region genes may control developmentally ordered T cell receptor [gamma] gene rearrangement." Thesis, Massachusetts Institute of Technology, 1995. http://hdl.handle.net/1721.1/32626.

Full text
Abstract:
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 1995.<br>On t.p., "[gamma] appears as the lower case Greek letter.<br>Includes bibliographical references (leaves 155-172).<br>by Jacki P. Goldman.<br>Ph.D.
APA, Harvard, Vancouver, ISO, and other styles
4

Madisen, Linda. "Lymphoid specific elements deregulate c-myc transcription following chromosomal translocation in murine plasmacytoma and human Burkitt's lymphoma cells /." Thesis, Connect to this title online; UW restricted, 1996. http://hdl.handle.net/1773/6324.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

James, Leonard Philip. "Myc and Mad target genes /." Thesis, Connect to this title online; UW restricted, 2000. http://hdl.handle.net/1773/5093.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Melkoumian, Zaroui K. "Pharmacological regulation of c-myc gene expression in human breast cancer cells." Morgantown, W. Va. : [West Virginia University Libraries], 2001. http://etd.wvu.edu/templates/showETD.cfm?recnum=2218.

Full text
Abstract:
Thesis (Ph. D.)--West Virginia University, 2001.<br>Title from document title page. Document formatted into pages; contains x, 152 p. : ill. (some col.). Vita. Includes abstract. Includes bibliographical references (p. 119-149).
APA, Harvard, Vancouver, ISO, and other styles
7

Abbas, Nasser. "Parthenogenesis in plants: putative functions of MCM genes." [S.l.] : [s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=964450941.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Harrison, David. "MCP-dependent chemotaxis in Rhodobacter sphaeroides." Thesis, University of Oxford, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.360292.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Souza, Ana Carolina Mamana Fernandes de. "Comparação das técnicas de PCR em tempo real e PCR para o estudo dos genes MYCN, DDX1 e NAG em pacientes portadores de neuroblastoma." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/5/5136/tde-21062007-141525/.

Full text
Abstract:
O neuroblastoma é o tumor sólido extra-cranial mais comum e mortal da infância, sendo o tempo de sobrevida nos casos mais agressivos ainda muito curto. Uma das esperanças nesses casos é que os estudos moleculares possam fornecer informações sobre os genes ou as vias moleculares que governam a patogênese dos neuroblastomas. Pois, há poucos genes como o MYCN, que foi descrito por estar diretamente ligado ao neuroblastoma. A amplificação deste oncogene ocorre em pouco mais de 25% dos neuroblastomas e é considerada como o mais importante marcador de prognóstico nestes tumores, sendo fortemente rel
APA, Harvard, Vancouver, ISO, and other styles
10

Vulcani-Freitas, Tânia Maria [UNIFESP]. "Perfil de expressão dos genes MYC, MYCN, TERT, ASPM e PRAME em Meduloblastoma." Universidade Federal de São Paulo (UNIFESP), 2010. http://repositorio.unifesp.br/handle/11600/9928.

Full text
Abstract:
Made available in DSpace on 2015-07-22T20:50:35Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-04-28<br>Meduloblastoma (MB) é o tumor maligno de sistema nervoso central (SNC) mais comum em criança, compreendendo 20% dos tumores primários de SNC e 40% dos tumores cerebelares da infância. Devido sua forte tendência metastática, o tratamento padrão pós-operatório inclui radio e quimioterapia, cujo impacto causa distúrbios endócrinos e de crescimento, e disfunção neurocognitiva a longo prazo. Frente a esses efeitos negativos, muitas pesquisas em meduloblastoma têm sido realizadas com in
APA, Harvard, Vancouver, ISO, and other styles
11

Marchese, Morales Adolfo. "Superbacteria carry new gene that makes them resist all antibacterials." Revista de Química, 2016. http://repositorio.pucp.edu.pe/index/handle/123456789/99925.

Full text
Abstract:
Un grupo de científicos de China ha encontrado un nuevo gen en las bacterias gram negativas, el MCR-1. Este gen ha sido responsable de otorgarle resistencia a estas bacterias patógenas ante la colistina, el antibacteriano que los médicos emplean como última arma para combatir ciertas infecciones multi-resistentes. Con este gen, las superbacterias serán potencialmente epidémicas y las enfermedades que se creían controladas, como la neumonía, la tuberculosis y las infecciones del tracto urinario, podrían ser nuevamente letales.<br>A group of Chinese scientists have found a new gene in gram negat
APA, Harvard, Vancouver, ISO, and other styles
12

Al-Sallami, Dheyaa Abdul Salam. "INTERROGATION OF CHROMOSOME 8Q24.21 REGION FOR GENES CRUCIAL FOR CARCINOGENESIS USING CRISPR-CAS9 APPROACHES." OpenSIUC, 2016. https://opensiuc.lib.siu.edu/theses/1994.

Full text
Abstract:
8q24.21 is a highly amplified region in cancer and associated with many epithelial cancer such as bladder, breast, colorectal and prostate cancer. The proto-oncogene c-myc is located in this region and surrounded by many lncRNAs genes such as PCAT family, CCAT family, PRNCR1. In this study, we used CRISPR-Cas9 constructs to knock out PCAT1, PRNCR1, CASC8, CASC11 and also the sequences between PCAT1-CASC11 and CASC8-CASC11in the prostate cancer cell PC3. The transfected cells with CRISPR-Cas9 targeting CASC11 gene had less proliferation ability comparing with the transfected cells with CRISPR-C
APA, Harvard, Vancouver, ISO, and other styles
13

Lemarteleur, Thibault Riou Jean-François. "Etude de ligand de l'ADN G-quadruplexe sur la transcription et la prolifération dans des lignées cellulaires humaines." [S.l.] : [S.n.], 2005. http://scdurca.univ-reims.fr/exl-doc/GED00000160.pdf.

Full text
APA, Harvard, Vancouver, ISO, and other styles
14

VIALE, AGNES. "La famille des genes de l'hormone de melanoconcentration (mch) : emergence de nouveaux genes exprimes chez les primates." Nice, 1997. http://www.theses.fr/1997NICE5181.

Full text
Abstract:
Chez les mammiferes, le gene de l'hormone de melanoconcentration (mch) code pour deux peptides, mch et nei, exprimes majoritairement dans l'hypothalamus. Chez l'homme, il existe deux genes mch : un gene mch authentique (sur le chromosome 12) et un gene mch variant (duplique sur le chromosome 5). Nous avons clone a partir d'une banque de yac le gene mch et ses regions 5' et 3' flanquantes. Ce gene est exprime chez l'humain dans le cerveau (hypothalamus) et a la peripherie. Par ailleurs, un profil de maturation different de la promch a ete revele a la peripherie et dans le snc chez l'homme. La s
APA, Harvard, Vancouver, ISO, and other styles
15

Straaten, J. P. van. "Studies on the human c-myc gene product." Thesis, University of Cambridge, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.377708.

Full text
APA, Harvard, Vancouver, ISO, and other styles
16

Lepique, Ana Paula. "Efeitos de ACTH, PMA e dcAMP na expressão de genes das famílias FOS e JUN do gene C-MYC e na atividade do fator de transcrição AP-1 em células adrenocorticais Y-1." Universidade de São Paulo, 1996. http://www.teses.usp.br/teses/disponiveis/46/46131/tde-18092008-093726/.

Full text
Abstract:
As células Y-1 pertencem a uma linhagem clonal de células funcionais de córtex adrenal de camundongo, que respondem a ACTH. Em células Y-1, ACTH promove a esteroidogênese (função) e tem efeitos regulatórios complexos na transição G0&#8594;G1&#8594;S do ciclo celular. ACTH promove a transição G0&#8594;G1, mas inibe a transição G1&#8594;S. É possível que a regulação do ciclo celular por ACTH seja mediada pelo controle da expressão dos proto-oncogenes das famílias fos, jun e myc. Nosso laboratório mostrou, anteriormente, que ACTH induz a expressão dos genes fos e jun, mas inibe c-myc. O objetivo
APA, Harvard, Vancouver, ISO, and other styles
17

Polischouk, Anya. "Molecular factors relevant to the radiosensitivity of human tumours /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-508-5.

Full text
APA, Harvard, Vancouver, ISO, and other styles
18

Barros, Selma Gouvêa de [UNESP]. "Detecção molecular quantitativa de cianobactérias hepatotóxicas através de PCR competitiva." Universidade Estadual Paulista (UNESP), 2010. http://hdl.handle.net/11449/87897.

Full text
Abstract:
Made available in DSpace on 2014-06-11T19:23:03Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-03-26Bitstream added on 2014-06-13T20:29:42Z : No. of bitstreams: 1 barros_sg_me_rcla.pdf: 569574 bytes, checksum: a41aac60a4eff140d6e766859b8399c7 (MD5)<br>Florações de cianobactérias tóxicas são atualmente um problema mundial devido a produção de toxinas. A microcistina é uma hepatotoxina comumente encontrada em corpos d´água e é produzida principalmente pelo gênero Microcystis. Recentemente a identificação, clonagem e seqüenciamento do agrupamento de genes responsáveis pela codificação d
APA, Harvard, Vancouver, ISO, and other styles
19

Cericatto, Rodrigo. "Expressão gênica do receptor estrogênico-a, bcl-2 e c-myc em fibroadenomas e no tecido mamário normal circunjacente." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2003. http://hdl.handle.net/10183/4629.

Full text
APA, Harvard, Vancouver, ISO, and other styles
20

Östergren, Tiolina. "Identification of MYCN and SOX9 target genes and a study of drug treatment effects in medulloblastoma." Thesis, Uppsala universitet, Institutionen för biologisk grundutbildning, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-262085.

Full text
Abstract:
Medulloblastoma (MB) is the most common malignant brain tumor affecting children. The transcription factors MYCN and SOX9 are associated with initiation, maintenance and recurrence of MB and are also connected to more aggressive tumors. In this study, a ChIP was performed to isolate DNA from genes that are transcriptionally regulated by these proteins. Identification of these target genes will reveal new potential drug targets and help us better understand the functions of MYCN and SOX9. The ChIP was not fully optimized during this project and the target genes were not sent for sequencing and
APA, Harvard, Vancouver, ISO, and other styles
21

Her, Yerim. "Functional analysis of species-specific genes that may contribute to Leishmania tropism." Thesis, University of York, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.556478.

Full text
Abstract:
Genome sequencing of three Leishmania species (L.infantum, L.major and L.brazitiensis) that cause different types of leishmaniasis has identified only a few species-specific genes that may contribute to Leishmania tropism in the host. This thesis describes the preliminary analysis of four Leishmania infantum species-specific genes and the functional analysis of one selected gene from the preliminary analysis, LinJ31.3030, which codes for a putative phosphatase. Transgenic parasites deleted for this sequence have been generated by sequential gene replacement and these analyses have demonstrated
APA, Harvard, Vancouver, ISO, and other styles
22

Zhang, Wenyun. "Polymorphism and divergence of two sex-linked genes from the non-recombining region of papaya (carica papaya) sex chromosomes." Miami University / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=miami1216405669.

Full text
APA, Harvard, Vancouver, ISO, and other styles
23

Popov, Nikita. "Expression and activity of Myc network proteins during cell cycle progression and differentiation /." Sundbyberg, 2004. http://diss.kib.ki.se/2004/91-7349-856-4/.

Full text
APA, Harvard, Vancouver, ISO, and other styles
24

Oliveira, Mariana Angelozzi de. "Caracterização de rearranjos cromossômicos em pacientes com malformações congênitas múltiplas e/ou retardamento mental (MCA/MR)." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/41/41131/tde-08072008-110038/.

Full text
Abstract:
As alterações cromossômicas estruturais associadas a fenótipos clínicos oferecem a oportunidade de identificação e localização de genes cujas mutações possam estar determinando essas patologias, tendo em vista a possibilidade de que esses genes podem ter sido alterados pelas quebras ou ter o número de cópias modificado. Um número cada vez maior de evidências aponta para a participação de certas seqüências do genoma na formação de rearranjos cromossômicos recorrentes e não recorrentes. Este trabalho compreendeu o estudo de duas translocações cromossômicas aparentemente equilibradas e uma duplic
APA, Harvard, Vancouver, ISO, and other styles
25

Toumaniantz, Gilles. "Caracterisation du mch-gene-overprinted polypeptide : une nouvelle proteine issue de la regulation post-transcriptionnelle du gene de l'hormone de melanoconcentration (mch)." Nice, 1999. http://www.theses.fr/1999NICE5356.

Full text
Abstract:
Le processus d'epissage alternatif permet de generer differentes proteines biologiquement actives a partir d'un meme gene. Par la technique de rt-pcr, nous avons mis en evidence un produit d'amplification minoritaire de taille inferieure au fragment correspondant a l'arnm de la melanin-concentating hormone (mch) a partir d'extraits hypothalamiques de differentes souches de rats. Apres sequencage, ce fragment c'est avere correspondre a un nouveau messager dans lequel les exons i et iii du gene mch sont directement joints. Cette association abouti a la production d'une nouvelle proteine, de sequ
APA, Harvard, Vancouver, ISO, and other styles
26

Tesell, Jessica M. "The Notch1-c-Myc Pathway Mediates Leukemia-Initiating Cell Activity in Mouse T-ALL Models: A Dissertation." eScholarship@UMMS, 2013. http://escholarship.umassmed.edu/gsbs_diss/671.

Full text
Abstract:
Although cure rates have significantly improved for children with T-cell acute lymphoblastic leukemia (T-ALL), 20-30% undergo induction failure or relapse with most succumbing to disease. Leukemia-initiating cells (L-ICs) are hypothesized to be resistant to conventional chemotherapy and radiation and are thereby responsible for disease recurrence. Using an in vivo limiting dilution assay, we previously showed that the murine T-ALL L-IC is quite rare, with only 0.003-0.05% of cells capable of initiating disease, and demonstrated that the L-IC is a subset of the leukemic DN3 thymic progenitor po
APA, Harvard, Vancouver, ISO, and other styles
27

Devall, Matthew Adrian Michael. "Epigenetic modification of mitochondrial genes in Alzheimer's disease (AD)." Thesis, University of Exeter, 2017. http://hdl.handle.net/10871/28434.

Full text
Abstract:
Alzheimer’s disease is a chronic, neurodegenerative disease characterised by amyloid plaque accumulation, neurofibrillary tangles and eventual neuronal cell loss. The complex aetiology exhibited in late-onset Alzheimer’s disease presents a considerable challenge in the field of genetics, with identified variants from genome-wide association studies collectively only explaining about a third of disease incidence. As such, new avenues are being explored to elucidate underlying mechanisms associated with disease onset and progression. In 2014, the first epigenome-wide association studies in Alzhe
APA, Harvard, Vancouver, ISO, and other styles
28

Marinho, Filho José Delano Barreto. "Participação das vias atm/atr e c-myc/gsh nos efeitos antitumorais da cordiaquinona J induzidos pelo estresse oxidativo." reponame:Repositório Institucional da UFC, 2012. http://www.repositorio.ufc.br/handle/riufc/5557.

Full text
Abstract:
MARINHO FILHO, José Delano Barreto. Participação das vias ATM/ATR e C-MYC/GSH nos efeitos antitumorais da cordiaquinona J induzidos pelo estresse exidativo. 2012. 173 f. Tese (Doutorado em Farmacologia) - Universidade Federal do Ceará. Faculdade de Medicina, Fortaleza, 2012.<br>Submitted by denise santos (denise.santos@ufc.br) on 2013-07-29T13:38:12Z No. of bitstreams: 1 2012_tese_jdbmarinhofilho.pdf: 3406223 bytes, checksum: 3c7724cbd89a3ac8cea011d4b36c1188 (MD5)<br>Approved for entry into archive by Erika Fernandes(erikaleitefernandes@gmail.com) on 2013-08-06T11:56:33Z (GMT) No. of bitstrea
APA, Harvard, Vancouver, ISO, and other styles
29

Schmidt, Marcelo Kruel. "Expressão imunohistoquímica do C-MYC na seqüência metaplasia-displasia-adenocarcinoma no esôfago." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2005. http://hdl.handle.net/10183/4697.

Full text
Abstract:
Introdução e Objetivos: O esôfago de Barrett (BE) desenvolve-se como conseqüência de uma agressão acentuada sobre a mucosa esofágica causada pelo refluxo gastresofágico crônico. É uma lesão precursora e exerce papel importante no desenvolvimento do adenocarcinoma esofágico (ACE). Inúmeras alterações genéticas estão presentes ao longo da transformação tumoral de uma célula, sendo o c-Myc um dos principais genes envolvidos na carcinogênese humana. O objetivo do presente estudo foi determinar a expressão do c-myc em pacientes com EB e com adenocarcinoma esofágico, e avaliar esta prevalência relac
APA, Harvard, Vancouver, ISO, and other styles
30

Heinrich, Stefanie May [Verfasser], and Matthias [Akademischer Betreuer] Griese. "Human SP-A-genes, structure, function- and lung diseases / Stefanie May Heinrich. Betreuer: Matthias Griese." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2011. http://d-nb.info/1018847243/34.

Full text
APA, Harvard, Vancouver, ISO, and other styles
31

PEREIRA, Cynthia Mara Brito Lins. "Expressão dos genes C-MYC, HER-2 e receptores hormonais como preditores de resposta à quimioterapia neoadjuvante em câncer mamário." Universidade Federal do Pará, 2010. http://repositorio.ufpa.br/jspui/handle/2011/2859.

Full text
Abstract:
Submitted by Ana Rosa Silva (arosa@ufpa.br) on 2012-07-23T13:47:00Z No. of bitstreams: 2 Dissertacao_ExpressaoGenesC-myc.pdf: 1582070 bytes, checksum: ded639d2c11fa3ed553f5b611b74750c (MD5) license_rdf: 23898 bytes, checksum: e363e809996cf46ada20da1accfcd9c7 (MD5)<br>Approved for entry into archive by Ana Rosa Silva(arosa@ufpa.br) on 2012-07-23T13:59:27Z (GMT) No. of bitstreams: 2 Dissertacao_ExpressaoGenesC-myc.pdf: 1582070 bytes, checksum: ded639d2c11fa3ed553f5b611b74750c (MD5) license_rdf: 23898 bytes, checksum: e363e809996cf46ada20da1accfcd9c7 (MD5)<br>Made available in DSpace on 2012
APA, Harvard, Vancouver, ISO, and other styles
32

Maqbool, Manzur Zakia. "The role of MCB elements in transcriptional activation of cell-cycle regulated genes in fission yeast." Thesis, University of Glasgow, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.274272.

Full text
APA, Harvard, Vancouver, ISO, and other styles
33

Kim, Ju Young. "Transcriptional regulation of glycosyltransferase genes in MCF-7 human breast cancer cell line following drug treatment." Master's thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/29866.

Full text
Abstract:
Bioinformatics is a subfield in computational science that is principally focused on developing methods and performing data analytics in the areas of proteomics and genomics. In this thesis I draw a link between proteomics and genomics by focusing on the regulation patterns of glycosyltransferase (GT) genes in breast cancer cell line following the treatment with a large set of Food and Drug Administration (FDA) approved drugs. This is based on the understanding that aberrant glycosylation in breast cancer tumours stem from altered GT gene expression. A major goal of genomic research is the ide
APA, Harvard, Vancouver, ISO, and other styles
34

May, Jürgen [Verfasser], Gisela [Gutachter] Jacobasch, and Rolf-Peter [Gutachter] Horstmann. "Einfluß von Genen der MHC-Klasse II und anderer polymorpher Gene auf Epidemiologie und klinische Manifestationen der Plasmodieninfektion / Jürgen May ; Gutachter: Gisela Jacobasch, Rolf-Peter Horstmann." Berlin : Humboldt-Universität zu Berlin, 2001. http://d-nb.info/1207659118/34.

Full text
APA, Harvard, Vancouver, ISO, and other styles
35

Mohamed-Hadley, Alisha. "THE ROLE OF THE STRESS RESPONSE GENE GADD45A IN MODULATING MYC MEDIATED APOPTOSIS AND DIFFERENTIATION." Diss., Temple University Libraries, 2011. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/126332.

Full text
Abstract:
Molecular Biology and Genetics<br>Ph.D.<br>The Gadd45 family of proteins is known to play a central role as cellular stress sensors that modulate the response of mammalian cells to different stressors, including oncogenic stress. Gadd45a expression is regulated during myeloid cell differentiation, and is also induced in response to acute stimulation with cytokines, myeloablation and inflammation. The proto-oncogene C-myc plays a pivotal role in growth control, differentiation and apoptosis in hematopoietic cells. Deregulated Myc in hematopoietic cells blocks the differentiation program and pre
APA, Harvard, Vancouver, ISO, and other styles
36

Corral, Marisol. "Caracterisation de genes cellulaires dont l'expression est associee a la cancerisation hepatique." Paris 6, 1987. http://www.theses.fr/1987PA066124.

Full text
APA, Harvard, Vancouver, ISO, and other styles
37

Hirth, Carlos Gustavo. "Valor prognóstico de marcadores de diferenciação neuroendócrina e de células-tronco em pacientes submetidos a prostatectomia radical por câncer de próstata localizado." reponame:Repositório Institucional da UFC, 2016. http://www.repositorio.ufc.br/handle/riufc/21568.

Full text
Abstract:
HIRTH, C.G. Valor prognóstico de marcadores de diferenciação neuroendócrina e de células-tronco em pacientes submetidos a prostatectomia radical por câncer de próstata localizado. 2016. 134 f. Dissertação (Mestrado em Patologia) - Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, 2016.<br>Submitted by Erika Fernandes (erikaleitefernandes@gmail.com) on 2017-01-18T13:27:42Z No. of bitstreams: 1 2016_dis_cghirth.pdf: 3230766 bytes, checksum: 651e7c54b6b9dec6b84cbf5bcfd553cd (MD5)<br>Approved for entry into archive by Erika Fernandes (erikaleitefernandes@gmail.com) on 2017-01-18T13:
APA, Harvard, Vancouver, ISO, and other styles
38

Tomc, Lyn Kathryn. "Role of MEF2 proteins in the activation of the c-jun and MCK genes in skeletal muscle /." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0018/MQ56210.pdf.

Full text
APA, Harvard, Vancouver, ISO, and other styles
39

傅子穎 and Tsi-wing Fu. "The expression and regulation of genes that may contribute to the etiology of diabetic neuropathy in mouse." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1998. http://hub.hku.hk/bib/B31215245.

Full text
APA, Harvard, Vancouver, ISO, and other styles
40

Nie, Mei. "The transcriptional regulation of the human IL-8 and MCP-1 genes in cultured primary mesangial cells." Thesis, University of Nottingham, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368257.

Full text
APA, Harvard, Vancouver, ISO, and other styles
41

Fu, Tsi-wing. "The expression and regulation of genes that may contribute to the etiology of diabetic neuropathy in mouse /." Hong Kong : University of Hong Kong, 1998. http://sunzi.lib.hku.hk/hkuto/record.jsp?B19872057.

Full text
APA, Harvard, Vancouver, ISO, and other styles
42

Barboza, Regina Felippe. "Estudo dos genes NDRG1, Par-4, osteonectina e pontina, em tecido mamário hiperplásico através de técnica de imunohistoquímica." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/5/5155/tde-04082011-133848/.

Full text
Abstract:
INTRODUÇÃO: O câncer de mama é uma das mais importantes causas de mortalidade feminina no mundo. Acredita-se que as lesões proliferativas do parênquima mamário sejam marcadoras de risco para câncer ou precursoras do carcinoma mamário. Apesar da intensa pesquisa na área do câncer de mama, os eventos moleculares precoces associados à evolução e progressão do câncer mamário ainda são pouco conhecidos. OBJETIVOS: Com a expectativa de melhor compreender os eventos iniciais da carcinogênese mamária examinamos um conjunto de oitenta e quarto lesões proliferativas mamárias quanto à expressão dos genes
APA, Harvard, Vancouver, ISO, and other styles
43

Lepique, Ana Paula. "O Gene c-myc e o controle do ciclo celular por ACTH em células adrenocorticais de camundongo da linhagem Y-1." Universidade de São Paulo, 2000. http://www.teses.usp.br/teses/disponiveis/46/46131/tde-14102008-085011/.

Full text
Abstract:
ACTH é o hormônio trófico que estimula a esteroidogênese, promove o crescimento e a manutenção do córtex adrenal. Porém, em linhagens adrenocorticais, assim como em culturas primárias, ACTH inibe a proliferação celular. A linhagem Y-1 de células adrenocorticais de camundongo tem as seguintes respostas a ACTH: aumento da esteroidogênese, arredondamento celular, bloqueio do ciclo celular em G1 e indução dos proto-oncogenes fos e jun. Esta linhagem também responde muito Sem a FGF2, um protótipo da família dos FGFs (Fibroblast Growth Factors) que regula diferenciação e proliferação de diversos tip
APA, Harvard, Vancouver, ISO, and other styles
44

Sigglekow, Nicholas David Garvan Institute of Medical Research Faculty of Medicine UNSW. "Mutated in colorectal cancer (MCC): a putative tumour suppressor gene in colorectal cancer." Publisher:University of New South Wales. Garvan Institute of Medical Research, 2009. http://handle.unsw.edu.au/1959.4/43617.

Full text
Abstract:
Colorectal cancer (CRC) remains a significant burden in contemporary society due to an aging population, unhealthy dietary choices and an increasingly sedentary lifestyle. While the underlying defects for many hereditary forms of CRC have been determined, many genetic and epigenetic changes promoting common sporadic CRCs have yet to be identified. The Mutated in Colorectal Cancer (MCC) gene, identified in 1991, was initially thought to be responsible for the hereditary form of CRC, familial adenomatous polyposis, before the discovery of the susceptibility gene Adenomatous Polyposis Coli (APC),
APA, Harvard, Vancouver, ISO, and other styles
45

Fukui, Hirokazu. "Regenerating gene protein may mediate gastric mucosal proliferation induced by hypergastrinemia in rats." Kyoto University, 1999. http://hdl.handle.net/2433/181731.

Full text
APA, Harvard, Vancouver, ISO, and other styles
46

Kieback, Elisa. "A new safeguard eliminates T cell receptor gene-modified auto-reactive T cells after adoptive therapy." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2008. http://dx.doi.org/10.18452/15819.

Full text
Abstract:
Der adoptive Transfer von TZR-modifizierten T Zellen ist mit potentiellen Risiken verbunden. Autoimmunreaktionen können auftreten, wenn Tumor-assoziierte Antigene auf normalem Gewebe erkannt werden, Fehlpaarung der TZR-Ketten zur Bildung eines autoreaktiven Rezeptors führen oder ein sonst anerger auto-reaktiver endogener Rezeptor aktiviert wird. Auch besteht das Risiko der malignen Transformation der Zelle durch Insertionsmutagenese. Daher ist es notwendig, die transferierten T Zellen im Fall schwerer Nebenwirkungen eliminieren zu können. Derzeit verfügbare Sicherheitsmechanismen sind für die
APA, Harvard, Vancouver, ISO, and other styles
47

Ahmed, Aden. "Utveckling av en PCR-baserad metod för detektion av plasmidburna kolistinresistens, mcr-1 och mcr-3 gener i extended-spectrum beta-lactamase (ESBL)-producerande enterobacteriaceae." Thesis, Högskolan Kristianstad, Sektionen för lärande och miljö, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:hkr:diva-17928.

Full text
Abstract:
Kolistin är ett gammalt polypeptidantibiotikum och används som sista utväg för behandling av allvarliga infektioner orsakad av multiresistenta gramnegativa bakterier. Nya studier har påvisat kolistinresistensgener, mcr (mobil colistin resistance), hos extended spectrum beta-lactamase (ESBL)-producerande Enterobacteriaceae. Mcr-genen ligger i plasmider som kan överföras mellan bakterier, vilket innebär att det är mycket svårare att behandla människor och djur vid infektion orsakad av patogen som erhållit denna resistens. Syfte med detta projekt var att utveckla en PCR-baserad metod för detektio
APA, Harvard, Vancouver, ISO, and other styles
48

Slahudeen, Sameera. "Red palm oil as a therapeutic agent in triple-negative breast cancer patients." University of the Western Cape, 2020. http://hdl.handle.net/11394/8094.

Full text
Abstract:
Magister Scientiae (Medical Bioscience) - MSc(MBS)<br>Purpose: Breast cancer is one of the most frequent and fatal diseases women all around the globe are challenged with today. In women, breast cancer has the highest mortality rate of all cancers and the incidence rate is on the increase. It is estimated that by the year 2025, 19.3 million women will become a victim of this grave health problem. This disease is a result of the formation of malignant tumours caused by genetic alterations that are involved in the proliferation of cells, cellular differentiation and the disturbance in homeostasi
APA, Harvard, Vancouver, ISO, and other styles
49

Luna, Brenda. "Prenatal Environmental Exposure and Neurodevelopmentally Important Gene Expression in Malformed Brain Tissue from Pediatric Intractable Epilepsy Patients." FIU Digital Commons, 2011. http://digitalcommons.fiu.edu/etd/445.

Full text
Abstract:
The primary objective of this proposal was to determine whether mitochondrial oxidative stress and variation in a particular mtDNA lineage contribute to the risk of developing cortical dysplasia and are potential contributing factors in epileptogenesis in children. The occurrence of epilepsy in children is highly associated with malformations of cortical development (MCD). It appears that MCD might arise from developmental errors due to environmental exposures in combination with inherited variation in response to environmental exposures and mitochondrial function. Therefore, it is postulated
APA, Harvard, Vancouver, ISO, and other styles
50

Sin, Yuan Yan (Angie). "How mitochondrial DNA mutations affect the growth of MCF-7 clones." Thesis, University of Canterbury. Biological Sciences, 2006. http://hdl.handle.net/10092/1392.

Full text
Abstract:
Mitochondria are the main sites for adenosine triphosphate (ATP) generation within most cells. Structural and functional alterations of mitochondria due to genetic abnormalities of mitochondria can cause respiratory chain dysfunction. In this study, the important role of mitochondria in energy metabolism was determined by comparing the effect of mitochondrial DNA (mtDNA) mutations on growth patterns and oxidative phosphorylation (OXPHOS) enzyme activities of six isolated clones (B5, B12, D4, D9, E1 and E8); as well as the effect of ATP supplement to culture using the slowest growing clone. The
APA, Harvard, Vancouver, ISO, and other styles
You might also be interested in the bibliographies on the topic 'Mcy genes' for other source types:
Journal articles Books
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography