Academic literature on the topic 'Mdr of mycobacterium tuberculosis'

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Journal articles on the topic "Mdr of mycobacterium tuberculosis"

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Zodape, G. V., S. N. Dharmashale, and V. S. Gaikwad. "Effect of Piper nigrum (Linn.) seeds extract and second line anti-tuberculosis drugs on a few Mycobacterium tuberculosis strains." Journal of Applied and Natural Science 13, no. 1 (2021): 402–6. http://dx.doi.org/10.31018/jans.v13i1.2497.

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Piper nigrum (Linn.) belonging to the family Piperaceae have been reported for its multitudinous medicinal values. The present study was undertaken to examine the direct effect of Ethionamide (ETH), Para amino salicylic acid (PAS), ethanolic extracts of P. nigrum on Mycobacterium tuberculosis (MTB) strain H37Rv and Multi drug-resistant (MDR)-strains-12, 19 and 21. The proportion method was used to detect the anti-mycobacterial drug susceptibility testing for mycobacteria using Lowenstein Jensen (LJ) medium. It was found that P. nigrum does not interfere with single or in the combination of bot
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Pratiwi, Ritha, Gemini Alam, Herlina Rante, and Nasrum Massi. "Aktivitas Anti Mycobacterium tuberculosis Strain H37Rv dan MDR (Multi Drug Resistant) dari Ekstrak Rimpang Curcuma mangga Val." Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) 6, no. 1 (2020): 70–76. http://dx.doi.org/10.22487/j24428744.2020.v6.i1.13102.

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TB is an infectious disease caused by the bacterium Mycobacterium tuberculosis. Empirically the plants that have long been used in medicine are Curcuma mangga rhizome, which shows pharmacological activity as an anti Mycobacterium tuberculosis drug. The objective of the research is to determine the ability of hexane and methanol extracts of Curcuma mangga in inhibiting the growth of Mycobacterium tuberculosis Strain H37Rv and MDR. The extraction of Curcuma mangga rhizome was conducted by maceration methode using hexane and methanol as the solvents, respectively. Both of extracts were made in 10
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Dey, Rishita, Sisir Nandi, Asmita Samadder, Aaruni Saxena, and Anil Kumar Saxena. "Exploring the Potential Inhibition of Candidate Drug Molecules for Clinical Investigation Based on their Docking or Crystallographic Analyses against M. tuberculosis Enzyme Targets." Current Topics in Medicinal Chemistry 20, no. 29 (2020): 2662–80. http://dx.doi.org/10.2174/1568026620666200903163921.

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Tuberculosis (TB) is a devastating disease responsible for millions of humans’ deaths worldwide. It is caused by a mycobacterial organism, the tubercle bacillus or Mycobacterium tuberculosis. Although TB can be treated, cured and can be prevented if patients take prescribed medicines, scientists have never come close to wiping it out due to a sharp rise in the incidence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) mycobacterium strains. Due to long regimen treatment and emergence of MDR and XDR-TB, it is urgent to re-engineer and reposition old drugs for developing new ant
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Espinosa-Pereiro, Juan, Adrian Sánchez-Montalvá, Maria Luisa Aznar, and Maria Espiau. "MDR Tuberculosis Treatment." Medicina 58, no. 2 (2022): 188. http://dx.doi.org/10.3390/medicina58020188.

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Multidrug-resistant (MDR) tuberculosis (TB), resistant to isoniazid and rifampicin, continues to be one of the most important threats to controlling the TB epidemic. Over the last few years, there have been promising pharmacological advances in the paradigm of MDR TB treatment: new and repurposed drugs have shown excellent bactericidal and sterilizing activity against Mycobacterium tuberculosis and several all-oral short regimens to treat MDR TB have shown promising results. The purpose of this comprehensive review is to summarize the most important drugs currently used to treat MDR TB, the re
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M, Menaka. "Assessment Of Antitubercular Activity Of Serankottai Nei: A Siddha Formulation Against Multidrug-Resistant Mycobacterium tuberculosis." African Journal of Biological Sciences 6, no. 2 (2024): 1353–58. http://dx.doi.org/10.48047/afjbs.6.2.2024.1353-1358.

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Multidrug-resistant Tuberculosis (MDR-TB), caused by Mycobacterium tuberculosis strains resistant to at least two key anti-mycobacterial drugs, is an escalating global health concern. This necessitates the exploration of alternative therapeutic options. The Siddha system of medicine offers a variety of formulations with potential efficacy against severe infections such as TB. This study investigates the effectiveness of Serankottai nei, a Siddha medicinal formulation, against MDR-TB. Different concentrations of Serankottai nei (2%, 4%, and 6%) were evaluated in vitro for their anti-mycobacteri
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Hosseiniporgham, Sepideh, and Leonardo A. Sechi. "A Review on Mycobacteriophages: From Classification to Applications." Pathogens 11, no. 7 (2022): 777. http://dx.doi.org/10.3390/pathogens11070777.

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Mycobacterial infections are a group of life-threatening conditions triggered by fast- or slow-growing mycobacteria. Some mycobacteria, such as Mycobacterium tuberculosis, promote the deaths of millions of lives throughout the world annually. The control of mycobacterial infections is influenced by the challenges faced in the diagnosis of these bacteria and the capability of these pathogens to develop resistance against common antibiotics. Detection of mycobacterial infections is always demanding due to the intracellular nature of these pathogens that, along with the lipid-enriched structure o
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Wulandari, Citra, and Ziske Maritska. "DETECTION OF FLUOROQUINOLONE RESISTANCE IN MYCOBACTERIUM TUBERCULOSIS ISOLATE CAUSED BY MUTATION IN THE GYRA GENE." Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya 9, no. 1 (2022): 117–22. http://dx.doi.org/10.32539/jkk.v9i1.16554.

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Drug-resistant tuberculosis is a public health concern. TB that is drug-resistant to rifampin and isoniazid is known as MDR-TB, whereas XDR-TB is MDR-TB that is also resistant to second-line medicines, such as fluoroquinolones (levofloxacin, ofloxacin, and moxifloxacin). rifampin-resistant tuberculosis (RR-TB), of which 78 percent had multidrug-resistant tuberculosis (MDR-TB) (MDR-TB). Fluoroquinolones are a class of broad-spectrum antimicrobials that have become increasingly popular in recent years. Fluoroquinolones have activity against Mycobacterium tuberculosis both in vitro and in vivo. F
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Diriba, Getu, Abebaw Kebede, Habteyes Hailu Tola, et al. "Mycobacterial Lineages Associated with Drug Resistance in Patients with Extrapulmonary Tuberculosis in Addis Ababa, Ethiopia." Tuberculosis Research and Treatment 2021 (September 18, 2021): 1–7. http://dx.doi.org/10.1155/2021/5239529.

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Background. In Ethiopia, tuberculosis (TB) is one of the most common causes of illness and death. However, there is limited information available on lineages associated with drug resistance among extrapulmonary tuberculosis patients in Ethiopia. In this study, researchers looked into Mycobacterium tuberculosis lineages linked to drug resistance in patients with extrapulmonary tuberculosis in Addis Ababa, Ethiopia. Methods. On 151 Mycobacterium tuberculosis isolates, a cross-sectional analysis was performed. Spoligotyping was used to characterize mycobacterial lineages, while a phenotypic drug
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Raja Iqbal Mulya Harahap, Juandika Juandika, and Dety Mulyanti. "PERBANDINGAN BIAYA PEMERIKSAAN LABORATORIUM PADA PASIEN TUBERKULOSIS MULTIDRUG RESISTANCE (TB-MDR) DENGAN TUBERKULOSIS EXTENSIVE DRUG RESISTANCE (TB-XDR): STUDI PADA RUMAH SAKIT TERSIER DI BANDUNG." DIAGNOSA: Jurnal Ilmu Kesehatan dan Keperawatan 1, no. 1 (2023): 01–09. http://dx.doi.org/10.59581/diagnosa-widyakarya.v1i1.156.

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Introduction. Tuberculosis (TB) is one of the oldest diseases known to attack humans, caused by the bacterium Mycobacterium tuberculosis. Multi-drug-resistant TB (MDR-TB) is a stage or condition in which Mycobacterium tuberculosis becomes minimally resistant to rifampicin administration and also insonicotinylhydrazine (INH). Extensive-drug-resistant TB (XDR-TB) is an MDR-TB with Mycobacterium tuberculosis immune characteristics against one of the fluoroquinolone class drugs and one of the second-line injection OAT (capreomycin, kanamycin, and amikacin). The aim of this study was to find out th
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Kaur, Harveen, Dilbag Singh, Amritpal Kaur, N. C. Kajal, and Mukul Sharma. "Central nervous system Tuberculomas in a patient with disseminated multi-drug resistant tuberculosis; A case report." International Journal of Current Research in Medical Sciences 7, no. 1 (2021): 1–5. http://dx.doi.org/10.22192/ijcrms.2021.07.01.001.

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Tuberculosis (TB) is one of the leading causes of death worldwide, particularly in low- and middle-income countries. Although Mycobacterium tuberculosis can involve any organ, most commonly the lung, central nervous system (CNS) tuberculosis is the most devastating form of the disease. Tuberculoma is the most common parenchymal lesion in CNS tuberculosis which could be found in any portion of the intracranial space. The global rates and numbers of drug resistant TB are rising. With increasing globalization, the spread of drug-resistant strains of TB has become a mounting global public health c
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Dissertations / Theses on the topic "Mdr of mycobacterium tuberculosis"

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Bonnet, Isabelle. "Rôle de whiB6 et kdpDE dans le clone MDR hypertransmissible B0/W148 de Mycobacterium tuberculosi." Electronic Thesis or Diss., Sorbonne université, 2023. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2023SORUS478.pdf.

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La tuberculose (TB) est, hors COVID, la première cause de décès lié à un agent infectieux. La détermination rapide du profil de résistance complet de Mycobacterium tuberculosis (Mtb) est essentielle pour démarrer un traitement adapté dans les cas de TB multirésistante (MDR) et ainsi limiter l’acquisition de résistances supplémentaires, augmenter les chances de succès thérapeutique et réduire la transmission de ces souches. Il existe 9 lignées principales au sein du complexe M. tuberculosis, dont 2 sont largement répandues dans le monde (L2 et L4). Au sein de la lignée 2, le clone W148 (ou comp
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SHARMA, KRITIKA. "TO DECIPHERTHE ROLE OF TA SYSTEMS IN MYCOBACTERIUM TUBERCULOSIS." Thesis, DELHI TECHNOLOGICAL UNIVERSITY, 2021. http://dspace.dtu.ac.in:8080/jspui/handle/repository/18461.

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Mycobacterium tuberculosis is the bacteria responsible for the disease of the infamous Tuberculosis (TB). mtb is the major human pathogens prevalent in developing countries, with an appropriate number of 2 million deaths per year. This disease is treatable but the hurdles we face, this project helps in giving the new approach and better perspective. Latent Tb is the phase when the bacteria exits in one person’s body and unable to replicate properly due to healthy and good immunity response. But it shows its pathogenicity when the immune response gets degraded. The reason can be any othe
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Tarazona, Jurado David Demetrio. "Análisis genómico de Mycobacterium tuberculosis sensible, MDR y XDR aislados en el Perú." Master's thesis, Universidad Nacional Mayor de San Marcos, 2019. https://hdl.handle.net/20.500.12672/11597.

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Señala que la tuberculosis (TB) es una de las enfermedades más importantes en salud pública en el mundo y en el Perú tiene una notable importancia por el número de casos de TB registrados y el incremento de casos drogorresistentes en los últimos años. Se realizó el análisis genómico comparativo de tres genomas de Mycobacterium tuberculosis que mostraban características fenotípicas de sensibilidad a drogas (INS-SEN), multidrogorresistente (INS-MDR) y extremadamente resistente (INSXDR). Se determinó que los aislados de INS-MDR y de INS-XDR difieren en 6.1% SNPs, mientras que el análisis comparat
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SANTOS, Lorena Cristina. "Análise de resistência a antimicrobianos de cepas de Mycobacterium tuberculosis isoladas no Estado de Goiás." Universidade Federal de Goiás, 2010. http://repositorio.bc.ufg.br/tede/handle/tde/1567.

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Made available in DSpace on 2014-07-29T15:26:20Z (GMT). No. of bitstreams: 1 TeseLorenaCristina2010.pdf: 1826396 bytes, checksum: fc176dacea640559fe92237b2a050e60 (MD5) Previous issue date: 2010-12-07<br>Tuberculosis (TB) is a serious global public health. In Brazil for the confirmed TB cases is recommended a multi-drug therapy regimen which combines different drugs during at least 6 month. However, because of treatment inconsistency, the emergency and spread of drug resistant M. tuberculosis become a serious threat. Actually, strains resistant to at least one drug used in the TB treatment h
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Stoffels, Karolien. "Contribution to the research on drug resistant Mycobacterium tuberculosis." Doctoral thesis, Universite Libre de Bruxelles, 2014. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/209194.

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Tuberculosis (TB) is a potentially fatal contagious disease that can affect almost any part of the body but is mainly an infection of the lungs. It is caused by micro-organisms of the Mycobacterium tuberculosis complex. It is the second greatest killer worldwide due to a single infectious agent, after the Human Immunodeficiency Virus (HIV). Without treatment, fatality is 50% in immune competent persons. TB remains the leading cause of death among HIV positive persons, causing one fifth of the deaths. The World Health Organization estimates that one third of the world population is infected by
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Souza, Márcia Alves de. "Avaliação do desempenho da PCR Multiplex alelo específico para detecção de genes de Mycobacterium tuberculosis associados à resistência a Rifampicina e Isoniazida, a partir de amostra clínica." Universidade Federal do Amazonas, 2013. http://tede.ufam.edu.br/handle/tede/2565.

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Made available in DSpace on 2015-04-11T13:54:24Z (GMT). No. of bitstreams: 1 Marcia Alves de Souza.pdf: 1923965 bytes, checksum: 3ad1484efad384495579203b0e85259c (MD5) Previous issue date: 2013-05-30<br>FAPEAM - Fundação de Amparo à Pesquisa do Estado do Amazonas<br>A Tuberculose (TB) é uma doença infecciosa causada pelo complexo Mycobacterium tuberculosis, sendo considerada um grave problema de saúde pública mundial. Atualmente, isolados de M. tuberculosis resistentes a pelo menos um medicamento utilizado no tratamento da TB tem sido documentados em todos os países. De acordo com a Organi
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Willemse, Danicke. "Regulation of efflux in rifampicin resistant mutants of Mycobacterium tuberculosis." Thesis, Stellenbosch : Stellenbosch University, 2013. http://hdl.handle.net/10019.1/79820.

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Thesis (MScMedSc)--Stellenbosch University, 2013.<br>ENGLISH ABSTRACT: Multidrug resistant tuberculosis (MDR-TB), defined as having resistance to at least the first-line drugs, isoniazid and rifampicin (RIF), is a global health problem. Mutations in the rpoB gene, encoding the β-subunit of RNA polymerase, are implicated in RIF resistance - with the S531L and H526Y mutations occurring most frequently. The level of RIF resistance varies for strains with identical rpoB mutations, which suggests that other factors play a role in RIF resistance. Efflux has been implicated in determining the intrins
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Klotoe, Jésutondin Bernice Mélaine. "Développement de méthodes pour le diagnostic, le contrôle, la surveillance de la tuberculose à bacilles ultra-résistants et des souches épidémiques Beijing." Thesis, Université Paris-Saclay (ComUE), 2018. http://www.theses.fr/2018SACLS379/document.

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La tuberculose MDR/XDR (multi et ultrarésistante aux antituberculeux) causée par Mycobacterium tuberculosis constitue un problème de santé publique mondial. L’étude et l’identification des mutations responsables de la résistance sont des facteurs clés pour le contrôle et la surveillance de la tuberculose MDR/XDR. L’expansion de lignée L2/Beijing, une famille de souches originaire du Sud-Est de la Chine (Guangxi) potentiellement plus virulente, complique la maitrise de cette maladie. Dans ce contexte, nous avons développé le TB-EFI et le TB IS-NTF/RINT, deux méthodes moléculaires rapides, multi
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Nguyen, Quang Huy. "Genetic determinants and evolution of drug resistance in Mycobacterium tuberculosis in Vietnam : toward new diagnostic tools." Thesis, Montpellier, 2016. http://www.theses.fr/2016MONTT081/document.

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La tuberculose (TB), provoquée par Mycobacterium tuberculosis, est une des trois maladies prioritaires dans le monde. Les TB multi-résistantes (MDR) et ultra-résistantes (XDR-TB) représentent des obstacles majeurs pour la lutte antituberculeuse. Dans les pays à MDR-TB élevée, comme le Vietnam, la détection insuffisante de la résistance aux antibiotiques est un des facteurs principaux qui favorisent la transmission des souches résistantes. De plus, dans ces pays, encore très peu de choses sont connues sur la résistance à la pyrazinamide et aux antibiotiques de seconde ligne et sur les détermina
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Kuzeljevic, Brigitta. "The Potentials and Difficulties of Two New Drugs, TMC 207 and PA-824, against Drug-Susceptible and Drug-Resistant Strains of Mycobacterium tuberculosis." Thesis, Linnéuniversitetet, Institutionen för kemi och biomedicin (KOB), 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-25284.

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Tuberculosis has for decades been the leading cause of death, worldwide, originating from merely one infectious matter i.e. the bacilli Mycobacterium tuberculosis (MTB). It is killing approximately 1.5 million people every year. The World Health Organization (WHO) estimates that 2 billion people might be infected by this specific bacterium, and that there emerges about 9 million new, active cases of TB each year. The aim with this thesis is to elucidate the possibilities and the difficulties with two new drugs against susceptible and resistant, latent and replicating strains of M. tuberculosis
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Books on the topic "Mdr of mycobacterium tuberculosis"

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Bendinelli, Mauro, and Herman Friedman, eds. Mycobacterium tuberculosis. Springer US, 1988. http://dx.doi.org/10.1007/978-1-4684-5418-5.

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Mauro, Bendinelli, and Friedman Herman 1931-, eds. Mycobacterium tuberculosis. Plenum, 1988.

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Parish, Tanya, and Neil G. Stoker. Mycobacterium Tuberculosis Protocols. Humana Press, 2001. http://dx.doi.org/10.1385/1592591477.

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Tanya, Parish, and Stoker Neil G, eds. Mycobacterium tuberculosis protocols. Humana Press, 2001.

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Vinšová, Jarmila. Development of new MDR-tuberculosis drugs. Nova Science Publisher, 2010.

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Derek, Chadwick, Cardew Gail, and Symposium on Genetics and Tuberculosis (1997 : Cape Town, South Africa), eds. Genetics and tuberculosis. Wiley, 1998.

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International Medical Foundation of Japan and Southeast Asian Medical Information Center (International Medical Foundation of Japan), eds. Introduction to tuberculosis and mycobacteria. SEAMIC/IMFJ, 1990.

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Kanai, Komi. Introduction to tuberculosis and mycobacteria. SEAMIC/IMFJ, 1990.

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Mauro, Bendinelli, and Friedman Herman 1931-, eds. Mycobacterium tuberculosis: Interactions with the immune system. Plenum Press, 1988.

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Grange, John M. Guidelines for speciation within the Mycobacterium tuberculosis complex. World health Organization, 1994.

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Book chapters on the topic "Mdr of mycobacterium tuberculosis"

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Singh, Amit, Anil Kumar Gupta, and Sarman Singh. "Molecular Mechanisms of Drug Resistance in Mycobacterium tuberculosis: Role of Nanoparticles Against Multi-drug-Resistant Tuberculosis (MDR-TB)." In NanoBioMedicine. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-32-9898-9_12.

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Panaiotov, Stefan, Massimo Amicosante, Marc Govaerts, et al. "Mycobacterium tuberculosis: Tuberculosis." In BSL3 and BSL4 Agents. Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527645114.ch23.

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Panaiotov, Stefan, Massimo Amicosante, Marc Govaerts, et al. "Mycobacterium Tuberculosis: Tuberculosis." In BSL3 and BSL4 Agents. Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527645114.ch9.

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Stechenberg, Barbara. "Mycobacterium tuberculosis." In The Neurological Manifestations of Pediatric Infectious Diseases and Immunodeficiency Syndromes. Humana Press, 2008. http://dx.doi.org/10.1007/978-1-59745-391-2_24.

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Wilder-Smith, Einar P. "Mycobacterium Tuberculosis." In International Neurology. Wiley-Blackwell, 2010. http://dx.doi.org/10.1002/9781444317008.ch71.

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Dhiman, Rohan. "Mycobacterium tuberculosis." In Encyclopedia of Systems Biology. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-9863-7_947.

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Gillespie, Stephen H. "Mycobacterium tuberculosis." In Principles and Practice of Clinical Bacteriology. John Wiley & Sons, Ltd, 2006. http://dx.doi.org/10.1002/9780470017968.ch10.

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Lydyard, Peter M., Michael F. Cole, John Holton, et al. "Mycobacterium tuberculosis." In Case Studies in Infectious Disease, 2nd ed. CRC Press, 2023. http://dx.doi.org/10.1201/9781003155447-24.

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Jacobs, William R. "Mycobacterium tuberculosis." In Clinical Tuberculosis. CRC Press, 2020. http://dx.doi.org/10.1201/9781351249980-3.

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Smith, Kim Connelly, and Jeffrey R. Starke. "Mycobacterium tuberculosis." In Congenital and Perinatal Infections. Humana Press, 2006. http://dx.doi.org/10.1385/1-59259-965-6:233.

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Conference papers on the topic "Mdr of mycobacterium tuberculosis"

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Pramanik, Atreyi, Ajay Singh, Gouri Rani, Shival Dubey, and Srinivas Aluvala. "Revolutionizing Tuberculosis Treatment: Smart Technology Innovations for Mycobacterium tuberculosis Management." In 2024 International Conference on Smart Devices (ICSD). IEEE, 2024. http://dx.doi.org/10.1109/icsd60021.2024.10751489.

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D, Jereminth Muñoz, and Cristian Torres V. "Segmentation and Identification of Mycobacterium Tuberculosis (MTB)." In 2024 3rd International Congress of Biomedical Engineering and Bioengineering (CIIBBI). IEEE, 2024. https://doi.org/10.1109/ciibbi63846.2024.10784816.

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Nayyar, Akansha, Rahul Shrivastava, and Shruti Jain. "Drug Discovery for Mycobacterium Tuberculosis: An Experimental Analysis." In 2024 IEEE Region 10 Symposium (TENSYMP). IEEE, 2024. http://dx.doi.org/10.1109/tensymp61132.2024.10751822.

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Umam, Khairul, I. Ketut Eddy Purnama, Reza Fuad Rachmadi, and Sari Ayu Wulandari. "Detection of Mycobacterium Tuberculosis Using Real-time Detection Transformer." In 2024 International Seminar on Intelligent Technology and Its Applications (ISITIA). IEEE, 2024. http://dx.doi.org/10.1109/isitia63062.2024.10667784.

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Shurbeska, Boneva, Jasmina Nikolovska, Vladimir Mitrevski, et al. "Following the resistance pattern of mycobacterium tuberculosis." In Proceedings of the International Congress Public Health - Achievements and Challenges. Institute of Public Health of Serbia "Dr Milan Jovanović Batut", 2024. http://dx.doi.org/10.5937/batutphco24029s.

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Background: Tuberculosis (TB) accounts for over 40% of all mortality cases from communicable diseases in Europe.Multidrug-resistant TB (MDR-TB) is TB that does not respond to at least isoniazid and rifampicin, the 2 most powerful anti-TB drugs. 30 countries worldwide are classified as high multi drug resistant (MDR) TB burden countries, nine are in the European Region. The emergence of combined resistance to rifampicin and isoniazid (MDR-TB) is a matter of global concern. Methods and Objectives: Over a period of 10 years we examined patient specimens for TB. Culture-positive samples were subje
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Bastos, NA, VC Dias, MPM Bastos, et al. "ASPECTOS EPIDEMIOLÓGICOS E CLÍNICOS DE PROCESSOS INFECIOSOS CAUSADOS POR ESPÉCIES DE MYCOBACTERIUM." In Resumos do 54º Congresso Brasileiro de Patologia Clínica/Medicina Laboratorial. Zeppelini Editorial e Comunicação, 2022. http://dx.doi.org/10.5327/1516-3180.140s1.5852.

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Objetivo: Efetuar análise temporal (2016 a 2021) de aspectos epidemiológicos e clínicos de processos infecciosos causados por espécies de Mycobacterium, em pacientes atendidos em um laboratório clínico de Juiz de Fora, Minas Gerais. Método: Dados como idade, sexo e origem dos participantes, bem como etiologia da infecção, foram obtidos a partir de consulta em prontuário eletrônico. A etiologia foi determinada a partir de cultura utilizando ágar Lowenstein Jensen, com posterior caracterização da espécie de Mycobacterium por meio de reação em cadeia da polimerase (PCR). Conclusão: Devido a sua p
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Gerasimova, Alena, Anna Vyazovaya, Klavdia Levina, Marge Kütt, and Igor Mokrousov. "Tuberculosis in Estonia: a major impact of Russian MDR Mycobacterium tuberculosis Beijing B0/W148-cluster." In ERS International Congress 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/13993003.congress-2020.1602.

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Sung, Nacmoon, Jeong Su Cho, Ki-Hong Kim, et al. "Inactivation Of Multidrug Resistant (MDR)- And Extremely Drug Resistant (XDR)-Mycobacterium Tuberculosis Strains By Using Photodynamic Therapy (PDT)." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a3170.

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Mansoor, H., N. Hirani, VV Chavan, et al. "Clinical utility of target-based next-generation sequencing for drug-resistant tuberculosis: a pilot from Mumbai, India." In MSF Scientific Days International 2022. MSF-USA, 2022. http://dx.doi.org/10.57740/atfq-6s03.

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INTRODUCTION In countries with a high tuberculosis (TB) burden, poor access to drug susceptibility testing is a major bottleneck in diagnosing drug-resistant (DR) TB. India is estimated to account for a quarter of multidrug-resistant (MDR)-TB patients globally, with around 124,000 cases in 2020. Mumbai, a densely populated city in Maharashtra State, is a DR-TB hotspot with 24% of treatment- naïve cases, and 41% of previously-treated cases, having MDR-TB, and a high frequency of fluoroquinolone resistance occurring among these MDR-TB cases. Targeted next- generation sequencing (tNGS) is a promi
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Butova, T., M. Kuzhko, O. Solodiankin, et al. "Variability of resistance of Mycobacterium tuberculosis based on whole genome sequencing in patients with MDR and XDR-TB in the Kharkiv region,Ukraine." In ERS International Congress 2022 abstracts. European Respiratory Society, 2022. http://dx.doi.org/10.1183/13993003.congress-2022.437.

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Reports on the topic "Mdr of mycobacterium tuberculosis"

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แก้วกิติณรงค์, กมล, та นิพนธ์ อุดมสันติสุข. บทบาทของ MAIT cells ในการควบคุมการติดเชื้อแบคทีเรีย Mycobacterium tuberculosis : รายงานการวิจัย. จุฬาลงกรณ์มหาวิทยาลัย, 2016. https://doi.org/10.58837/chula.res.2016.28.

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วัณโรค (Tuberculosis) เป็นสาเหตุหลักของการเสียชีวิตจากโรคติดเชื้อของประชากรทั่วโลก (1) วัณโรคเกิดจากการติดเชื้อแบคทีเรีย Mycobacterium tuberculosis ภูมิต้านทานของร่างกายที่มีต่อเชื้อ Mycobacterium tuberculosis ประกอบด้วยเซลล์จากส่วนของ innate immunity และ adaptive immunity ในส่วนของ adaptive immunity กลุ่มของ T cells ที่มีส่วนสำคัญ ได้แก่ ทั้ง conventional T cells (ทั้ง CD8+ และ CD4+) และ non-conventional T cells (MAIT, NKT, CD1-restricted T cells) (2) MAIT (Mucosal-associated invariant T) cells จัดอยู่ในกลุ่มของ non-conventional T cells ที่พบได้ปริมาณมากตามเยื่อบุของร่างกาย รวมถึงปอด (3) นอกจ
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Yu, Guocan, Yanqin Shen, Bo Ye, and Yan Shi. Diagnostic accuracy of Mycobacterium tuberculosis cell free DNA for tuberculosis: A protocol of systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2020. http://dx.doi.org/10.37766/inplasy2020.11.0101.

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Cook, Ryan, Ryan Barnhart, and Sudipta Majumdar. Effect of pH on the Kinetics of Alanine Racemase from Mycobacterium tuberculosis. Journal of Young Investigators, 2019. http://dx.doi.org/10.22186/jyi.36.1.1-4.

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Stirling, Shannon, Sudipta Majundar, Jaeju Ko, and John Ford. Monomer-dimer Equilibrium of Mycobacterium tuberculosis Alanine Racemase Depends on Buffer Conditions. Journal of Young Investigators, 2019. http://dx.doi.org/10.22186/jyi.36.4.50-54.

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Nelson, Scott. Dock & Discover: Sensitizing Mycobacterium tuberculosis to Oxidative Assault via MazG Inhibition. ResearchHub Technologies, Inc., 2025. https://doi.org/10.55277/researchhub.lfd36v5i.

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Tumwasorn, Somying, Ajcharaporn Sawatpanich, Nibondh Udomsantisuk, and Kamon Kawkitinarong. Development of test kit for detection of rifampin resistance in mycobacterium tuberculosis by PCR-reverse line blot hybridization. Faculty of Medicine, Chulalongkorn University, 2006. https://doi.org/10.58837/chula.res.2006.25.

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A genetic test by PCR-reverse line blot hybridization was developed for rapid detection of mycobacterium tuberculosis and rifampin resistance simultaneously. Duplex PCR targeting IS 6110 and rpoB gene was employed to detect M. tuberculosis and the rpoB fragment with rifampin resistance hot spot region. The analytical sensitivity of duplex PCR for IS 6110 and rpoB gene was found to be 10 and 100fg of M.Tuberculosis H37Rv DNA, respectively. Since duplex PCR was specific to M. tuberculosis complex, it was thus able to be applied directly in clinical specimens. Oligonucleotide probes were designed
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Yusim, Karina, Bette T. M. Korber, Shihai Feng, and Chang-Shung Tung. Compensatory mutation in RpoC restores fitness to rifampicin-resistant multi-drug resistant Mycobacterium tuberculosis. Office of Scientific and Technical Information (OSTI), 2012. http://dx.doi.org/10.2172/1049993.

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Fan, Lichao. Diagnostic accuracy of Xpert MTB/RIF for Mycobacterium tuberculosis in pediatric bronchial lavage fluid: a meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.4.0118.

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ลออปักษา, อารีรัตน์, วิมลมาศ ลิปิพันธ์, พิณทิพย์ พงษ์เพ็ชร та กิ่งฟ้า ทรัพย์มนชัย. การศึกษาสภาวะที่เหมาะสมของ semicarbazide ในการวิเคราะห์หาปริมาณยาปฏิชีวนะที่ผสมกับ streptomycin โดยวิธีทางจุลชีววิทยา : รายงานการวิจัย. จุฬาลงกรณ์มหาวิทยาลัย, 1987. https://doi.org/10.58837/chula.res.1987.13.

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ความเข้มข้นของ semicarbazide hydrochloride ต่ำสุดที่มีผลยับยั้งการเจริญของเชื้อทดสอบ Sarcina lutea ATCC 9341, Staphylococcus aureus ATCC 6538P และ Bacillus subtilis ATCC 6633 ที่ใช้ในการวิเคราะห์ยาปฏิชีวนะมีค่าเท่ากับ 6.0, 10.0 และ 4.0 มก/มล. ตามลำดับ ดังนั้นเพื่อป้องกันผลรบกวนในการวิเคราะห์ยาปฏิชีวนะต้องใช้ความเข้มข้นของ semicarbazide hydrochloride ต่ำกว่าค่านี้ streptomycin ในความเข้มข้น 100 ไมโครกรัม/มล. จะถูกยับยั้งฤทธิ์การฆ่าเชื้อทดสอบ B. subtilis ได้โดยใช้ semicarbazide hydrochloride ในความเข้มข้นต่ำสุด 1.5 มก./มล. ปริมาตรเท่ากัน บ่มที่อุณหภูมิ 30 องศาเซลเซียส นาน 180 นาที และความเข้มข้น
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Patarakul, Kanitha, and Yong Poovoravan. Study of homology of mce and invA genes among different serovars of Leptospira interrogans and their in vivo expression. Faculty of Medicine, Chulalongkorn University, 2010. https://doi.org/10.58837/chula.res.2010.13.

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Leptospirosis is a worldwide zoonotic disease. Pathogenesis of leptospirosis is not well understood. Identification of virulence factors of pathogenic Leptospira and their roles in pathogenesis is crucial. Based on available whole-genome sequences of Leptospira, two presumptive virulence genes which are homologous to the invasionA (invA) gene of Rickettsia prowazekii and the mammalian cell entry (mce) gene of Mycobacterium tuberculosis, have been identified. The function of these genes may involve in the attachment and invasion of eukaryotic cells. We proposed that these gene homologues should
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