Relevant bibliographies by topics / Mechanisms involved in regulation of Systemic Blood Pressure

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Academic literature on the topic 'Mechanisms involved in regulation of Systemic Blood Pressure'

Author: Grafiati
Published: 4 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "Mechanisms involved in regulation of Systemic Blood Pressure"

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Peysh, A. Patel. "Mechanisms involved in regulation of Systemic Blood Pressure." Archives of Clinical Hypertension 3, no. 1 (2017): 016–20. https://doi.org/10.17352/ach.000014.

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Regulation of the circulatory system to maintain a constant arterial pressure is critical in ensuring adequate perfusion to meet metabolic requirements of tissues. Blood pressure (BP) can be considered in the context of Ohm’s law, whereby BP (analogous to voltage) is directly proportional to the product of cardiac output (current) and total vascular resistance (TPR). Acute regulatory mechanisms are coordinated in the cardiovascular control centres in the brainstem, which are themselves infl uenced by impulses from other neural centres in addition to sensors both intrinsic and extrinsic t
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Patel, PA, and N. Ali. "Mechanisms involved in regulation of Systemic Blood Pressure." Archives of Clinical Hypertension 3, no. 1 (2017): 016–20. http://dx.doi.org/10.17352/ach.000014.

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Huc, Tomasz, Halina Jurkowska, Maria Wróbel, Kinga Jaworska, Maksymilian Onyszkiewicz, and Marcin Ufnal. "Colonic hydrogen sulfide produces portal hypertension and systemic hypotension in rats." Experimental Biology and Medicine 243, no. 1 (2017): 96–106. http://dx.doi.org/10.1177/1535370217741869.

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Hydrogen sulfide, a toxic gas, at low concentrations is also a biological mediator in animals. In the colon, hydrogen sulfide is produced by intestinal tissues and gut sulfur bacteria. Gut-derived molecules undergo liver metabolism. Portal hypertension is one of the most common complications contributing to the high mortality in liver cirrhosis. We hypothesized that the colon-derived hydrogen sulfide may affect portal blood pressure. Sprague-Dawley rats were maintained either on tap water (controls) or on water solution of thioacetamide to produce liver cirrhosis (CRH-R). Hemodynamics were mea
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Charkoudian, N., and B. G. Wallin. "Sympathetic Neural Activity to the Cardiovascular System: Integrator of Systemic Physiology and Interindividual Characteristics." Comprehensive Physiology 4, no. 2 (2014): 827–50. https://doi.org/10.1002/j.2040-4603.2014.tb00562.x.

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AbstractThe sympathetic nervous system is a ubiquitous, integrating controller of myriad physiological functions. In the present article, we review the physiology of sympathetic neural control of cardiovascular function with a focus on integrative mechanisms in humans. Direct measurement of sympathetic neural activity (SNA) in humans can be accomplished using microneurography, most commonly performed in the peroneal (fibular) nerve. In humans, muscle SNA (MSNA) is composed of vasoconstrictor fibers; its best‐recognized characteristic is its participation in transient, moment‐to‐moment control
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Ahmad, Hafiz, Huma Khan, Shabirul Haque, Shameem Ahmad, Namita Srivastava, and Azhar Khan. "Angiotensin-Converting Enzyme and Hypertension: A Systemic Analysis of Various ACE Inhibitors, Their Side Effects, and Bioactive Peptides as a Putative Therapy for Hypertension." Journal of the Renin-Angiotensin-Aldosterone System 2023 (June 21, 2023): 1–9. http://dx.doi.org/10.1155/2023/7890188.

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Hypertension is a major risk factor for heart attack, produce atherosclerosis (hardening of the arteries), congestive heart failure, stroke, kidney infection, blindness, end-stage renal infection, and cardiovascular diseases. Many mechanisms are involved in causing hypertension, i.e., via calcium channels, alpha and beta receptors, and the renin-angiotensin system (RAS). RAS has an important role in blood pressure control and is also involved in the metabolism of glucose, homeostasis, and balance of electrolytes in the body. The components of RAS that are involved in the regulation of blood pr
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Improta Caria, Alex, Carolina Nonaka, Ciro Pereira, Milena Soares, Simone Macambira, and Bruno Souza. "Exercise Training-Induced Changes in MicroRNAs: Beneficial Regulatory Effects in Hypertension, Type 2 Diabetes, and Obesity." International Journal of Molecular Sciences 19, no. 11 (2018): 3608. http://dx.doi.org/10.3390/ijms19113608.

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MicroRNAs are small non-coding RNAs that regulate gene expression post-transcriptionally. They are involved in the regulation of physiological processes, such as adaptation to physical exercise, and also in disease settings, such as systemic arterial hypertension (SAH), type 2 diabetes mellitus (T2D), and obesity. In SAH, microRNAs play a significant role in the regulation of key signaling pathways that lead to the hyperactivation of the renin-angiotensin-aldosterone system, endothelial dysfunction, inflammation, proliferation, and phenotypic change in smooth muscle cells, and the hyperactivat
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Timasheva, Ya R. "IMMUNOLOGICAL ASPECTS OF ESSENTIAL HYPERTENSION." Medical Immunology (Russia) 21, no. 3 (2019): 407–18. http://dx.doi.org/10.15789/1563-0625-2019-3-407-418.

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According to modern concept of the etiopathogenesis of essential hypertension, immune cells play an important role in its development. Mediators produced by immunocompetent cells participate in the initiation and maintenance of chronic systemic inflammation and promote the development of vascular remodeling which is an important part of the pathogenesis of the disease and target organ damage. The immune mechanisms underlying blood pressure elevation include the activation of innate and adaptive immune cells. Endothelial damage triggers an inflammatory cascade, causing migration of the immune c
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Еркудов, В. О., and А. П. Пуговкин. "Role of kidneys in regulation of arterial pressure in normal conditions and following changes in circulating blood volume." Nauchno-prakticheskii zhurnal «Patogenez», no. 2() (June 4, 2019): 80–90. http://dx.doi.org/10.25557/2310-0435.2019.02.80-90.

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В лекции рассмотрено значение почечных механизмов контроля артериального давления и объёма циркулирующей крови в норме и при широко распространённых в клинической практике условиях: кровопотере и инфузии дополнительного объёма жидкости в сосудистое русло. Подчеркивается, что с почками связаны два контура регуляции кровообращения: один, где регулируемым параметром является системное артериальное давление, реализуется через ренин-ангиотензиновую систему, а второй, где регулируемым параметром является объём циркулирующей крови - через гипоталамо-гипофизарную систему. Даётся патофизиологическое оп
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Martinez-Caro, Leticia, NICOLAS NIN, Carolina Sanchez-Rodriguez, et al. "Inhibition of nitro-oxidative stress attenuates pulmonary and systemic injury induced by high–tidal volume mechanical ventilation." Shock 44, no. 1 (2025): 36–43. https://doi.org/10.1097/SHK.0000000000000381.

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Mechanisms contributing to pulmonary and systemic injury induced by high tidal volume (VT) mechanical ventilation are not well known. We tested the hypothesis that increased peroxynitrite formation is involved in organ injury and dysfunction induced by mechanical ventilation. Male Sprague-Dawley rats were subject to low- (VT, 9 mL/kg; positive end-expiratory pressure, 5 cmH2O) or high- (VT, 25 mL/kg; positive end-expiratory pressure, 0 cmH2O) VT mechanical ventilation for 120 min, and received 1 of 3 treatments: 3-aminobenzamide (3-AB, 10 mg/kg, intravenous, a poly adenosine diphosphate ribose
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Peltsch, Heather, Sandhya Khurana, Collin J. Byrne, et al. "Cardiac phenylethanolamine N-methyltransferase: localization and regulation of gene expression in the spontaneously hypertensive rat." Canadian Journal of Physiology and Pharmacology 94, no. 4 (2016): 363–72. http://dx.doi.org/10.1139/cjpp-2015-0303.

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Phenylethanolamine N-methyltransferase (PNMT) is the terminal enzyme in the catecholamine biosynthetic pathway responsible for adrenaline biosynthesis. Adrenaline is involved in the sympathetic control of blood pressure; it augments cardiac function by increasing stroke volume and cardiac output. Genetic mapping studies have linked the PNMT gene to hypertension. This study examined the expression of cardiac PNMT and changes in its transcriptional regulators in the spontaneously hypertensive (SHR) and wild type Wistar-Kyoto (WKY) rats. SHR exhibit elevated levels of corticosterone, and lower le
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Books on the topic "Mechanisms involved in regulation of Systemic Blood Pressure"

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Levy, Jerrold H., and David Faraoni. Pathophysiology and causes of severe hypertension. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0162.

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Hypertension affects multiple groups of patients characterized by different clinical presentations and a spectrum of potential causes. The pathophysiology is complex and multifactorial. Although most patients are labelled ‘essential hypertension’, multiple mechanisms are involved in blood pressure regulation. Factors that influence blood pressure homeostasis include endothelial function, the renin-angiotensin system, and the sympathetic nervous system. In elderly patients, hypertension is common as the vascular system and arterial stiffness also contribute. Other important factors include infl
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Gonzalez-Albarrán, Olga, and Luis M. Ruilope. The kidney and control of blood pressure. Edited by Neil Turner. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0210.

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The kidneys can be at the root of the development of arterial hypertension or they can participate in the maintenance of hypertension and its sequels. Renal alterations interfering with the regulation of sodium homeostasis or facilitating the generation of vasoconstrictors, particularly angiotensin II, are involved in the dysregulation of arterial blood pressure that underlies the development of arterial hypertension. The biology of angiotensin is described in detail.The kidneys are also the mediator of hypertension in such examples as renal ischaemia and hyperaldosteronism. The role of renal
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Whittle, Ian. Raised intracranial pressure, cerebral oedema, and hydrocephalus. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780198569381.003.0604.

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The brain is protected by the cranial skeleton. Within the intracranial compartment are also cerebrospinal fluid, CSF, and the blood contained within the brain vessels. These intracranial components are in dynamic equilibrium due to the pulsations of the heart and the respiratory regulated return of venous blood from the brain. Normally the mean arterial blood pressure, systemic venous pressure, and brain volume are regulated to maintain physiological values for intracranial pressure, ICP. There are a range of very common disorders such as stroke, and much less common, such as idiopathic intra
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Dussaule, Jean-Claude, Martin Flamant, and Christos Chatziantoniou. Function of the normal glomerulus. Edited by Neil Turner. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0044_update_001.

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Glomerular filtration, the first step leading to the formation of primitive urine, is a passive phenomenon. The composition of this primitive urine is the consequence of the ultrafiltration of plasma depending on renal blood flow, on hydrostatic pressure of glomerular capillary, and on glomerular coefficient of ultrafiltration. Glomerular filtration rate (GFR) can be precisely measured by the calculation of the clearance of freely filtrated exogenous substances that are neither metabolized nor reabsorbed nor secreted by tubules: its mean value is 125 mL/min/1.73 m² in men and 110 mL/min/1.73 m
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Book chapters on the topic "Mechanisms involved in regulation of Systemic Blood Pressure"

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Mifune, Mizuo, and Yoshihiko Kanno. "Hypertension as Three Systematic Dysregulations of Na+ Homeostasis in Terrestrial Mammal, and Salt in Gut Might Cause Brain Inflammation." In Psychology and Patho-physiological Outcomes of Eating [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.98904.

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Although Na+ homeostasis in vivo is essential for mammals, it is known that excessive salt (NaCl) intake has played a major role in the development of hypertension. In vivo, there is a hormonal system, the renin-angiotensin-aldosterone system (RAAS), that specializes in regulating Na+ retention, especially the amount of Na+ in plasma. Na+ homeostasis in vivo has been achieved mainly by the RAAS, through regulation of vascular tonus (blood pressure) and Na+ handling in the kidney (Na+ diuresis). Recent studies have revealed a third mechanism of Na+ homeostasis in vivo: regulation of interstitia
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Singh, Aman, and Krishna Singh. "Pathology of the Renin-Angiotensin-Aldosterone System." In Renin-Angiotensin-Aldosterone System - Latest Trends [Working Title]. IntechOpen, 2024. https://doi.org/10.5772/intechopen.1007937.

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The proposed chapter will involve role of different mechanisms in renin-angiotensin system (RAS) leads to regulation of blood pressure and diseases such as hypertension, heart failure and renal disease. We will also discuss how RAS provides potentials therapeutic target in the treatment of hypertension, kidney disease, and heart disease. There are many drugs which affects different mechanisms of the RAS system and accordingly being used to block different targets in different diseases. We will talk about the success and failures of these drugs. At the end we will discuss clinical trials and th
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Dressen, Kirk, and Archit Sharma. "Regulation of Circulation and Blood Volume." In Basic Anesthesia Review, edited by Alaa Abd-Elsayed. Oxford University PressNew York, 2024. http://dx.doi.org/10.1093/med/9780197584569.003.0277.

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Abstract Circulation is regulated by neural, endocrine, and autoregulatory systems via control of systemic arterial pressure and heart function. Vasomotor fibers reach small arteries, arterioles, venules, and veins from sympathetic nerve origins in the medulla and pons known as the vasomotor center. Both increased and decreased blood volumes can have clinical complications and hence the maintenance of blood volume is crucial to normal perfusion of body tissues. Blood volume, normally proportioned with extracellular fluid in the body, is closely controlled through a combination of factors. This
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Di Rienzo Marco, Parati Gianfranco, Pedotti Antonio, and Castiglioni Paolo. "1/f Modeling of Blood Pressure and Heart Rate Spectra." In Studies in Health Technology and Informatics. IOS Press, 1997. https://doi.org/10.3233/978-1-60750-879-3-45.

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The first observations of a 1/f trend in the spectrum of heart rate (HR) and blood pressure (BP) signals date back to 1982 and 1990, respectively. Ever since, a number of studies have suggested that the analysis of this spectral trend may be a valuable tool for investigating the physiological mechanisms involved in cardiovascular regulation and for assessing their derangement in pathological conditions. The spectral analysis of BP and HR tracings recorded in cats before and after the surgical opening of the baroreflex loop, offered us the opportunity to address some yet unclear aspects related
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Gerbino, Andrea, and Monica Carmosino. "Methods for Studying the Activity of Natural Extracts on Renal Transporters İnvolved in the Regulation of Blood Pressure." In Methods for Preclinical Evaluation of Bioactive Natural Products. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815123043123010010.

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Hypertension is one of the leading causes of chronic kidney disease (CKD) due to the deleterious effects that increased blood pressure (BP) has on kidney vasculature. Patients with CKD and hypertension often require a combination of antihypertensive medications to target BP. Several classes of antihypertensive/diuretic agents may have a role in the treatment of CKD and hypertension. Besides these conventional therapies, it is extremely useful to identify new natural sources (herbs and botanicals) of diuretics and their targets in the kidney that can be used alone or in combination with traditi
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Carter S.D., Repka C.P., Sprod L.K., Hayward R., and Schneider C.M. "Cancer rehabilitation exercise-mediated improvements over a twelve-year period in cancer survivors." In Assistive Technology Research Series. IOS Press, 2010. https://doi.org/10.3233/978-1-60750-080-3-181.

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Cancer detection and treatment have improved in recent years, resulting in millions of cancer survivors living with the negative side effects of cancer therapies. The increase in the number of cancer survivors necessitates the development of strategies that can counteract these side-effects. One such strategy could be the implementation of prescriptive exercise interventions. Purpose: To summarize the exercise response in cancer survivors following exercise training over a 12-year period. Methods: Five hundred-nineteen cancer patients participated in fitness assessments which examined cardiore
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Esra Bihter Gürler, Hülya Çevik ARAS, and Nagihan Bostanci. "Functional Changes in Metabolic Syndrome." In Metabolic Syndrome: A Comprehensive Update with New Insights. BENTHAM SCIENCE PUBLISHERS, 2025. https://doi.org/10.2174/9789815322132125010005.

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Metabolic Syndrome (MetS) is a condition characterized by the cooccurrence of several cardiovascular risk factors, including insulin resistance, obesity, dyslipidemia, and hypertension. The development of MetS is closely linked to visceral adiposity, which refers to fat accumulation around critical vital organs in the abdominal cavity. Visceral fat is metabolically active and produces adipokines, proteins that regulate energy balance and play a role in inflammation and atherosclerosis. Some adipokines, such as leptin and adiponectin, have beneficial effects on glucose homeostasis and are consi
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Conference papers on the topic "Mechanisms involved in regulation of Systemic Blood Pressure"

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Tiwari, Tushar, Vikas Kumar Sharma, and Pranab Kumar Dan. "Reliability and Safety Embedded Design Thinking and Frugal Engineering-based Approach in Assistive Product System Engineering." In 15th International Conference on Applied Human Factors and Ergonomics (AHFE 2024). AHFE International, 2024. http://dx.doi.org/10.54941/ahfe1005303.

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Product system engineering, the mainstay in providing utility, is an integral part of system engineering, where reliability and safety remain indispensable considerations, which is more pronounced in the present case of an assistive product system of the wheelchair extended with the sit-to-stand feature, closely bound with the users. Product system engineering involves designing and developing sit-to-stand wheelchairs that meet user-specific requirements and goals [25]. It defines the requirement and objective of the assistive product that consists of conceptual design, feasibility assessment,
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