Relevant bibliographies by topics / Meclizine

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Meclizine'

Author: Grafiati
Published: 5 June 2025
Last updated: 2 August 2025

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Journal articles on the topic "Meclizine"

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Gowramma, Byran, Ramachandran Senthil Kumar, Rajagopal Kalirajan, Kaviarasan Lakshmanan, and Subramanian Nainar Meyyanathan. "Enantiomeric Separation of Meclizine Hydrochloride in Pharmaceutical Dosage Form by HPLC Method." Current Drug Research Reviews 12, no. 1 (2020): 63–71. http://dx.doi.org/10.2174/2589977511666191211123337.

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Objective: A basic, powerful and isocratic chiral fluid chromatographic technique was created and approved for the enantiomeric partition of meclizine hydrochloride in pharmaceutical dose structure. Methods: The chromatographic partition was accomplished on Phenomenex® Lux Cellulose 1 (250 mm x 4.6 mm i.d, 5 μm molecule size) section utilizing portable stage framework containing acetonitrile: 25mM ammonium bicarbonate (75:25%v /v). The versatile stage was siphoned on the segment at the stream pace of 1.0 mL/min, and UV recognition was done at 230 nm. Result: The breaking points of recognition
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Samantha, McGlone. "Meclizine prescriptions in the Emergency Department and return visits in the elderly population." Annals of Clinical Hypertension 5, no. 1 (2021): 003–7. http://dx.doi.org/10.29328/journal.ach.1001026.

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Background: Meclizine is a commonly prescribed medication for patients discharged from the Emergency Department (ED) with a diagnosis of peripheral vertigo, however it is on the Beers list of medications to avoid in elderly patients. Objectives: This study aims to determine the correlation between use of meclizine and return visits to the ED within 1 week in patients > 65 years old. Methods: This is a retrospective observational study conducted at 2 urban tertiary care EDs over 5 years. Inclusion criteria included patients > 65 years who were given meclizine in the ED or discharged with
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Sharma, Sanjay Kumar, and Rakesh P. Patel. "Enhancing the Solubility and Dissolution Rate of Meclizine Hydrochloride by Inclusion Complex." Journal of Drug Delivery and Therapeutics 9, no. 4 (2019): 57–64. http://dx.doi.org/10.22270/jddt.v9i4.2981.

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Meclizine Hydrochloride is an Anti-Histamine drugs with very low bioavailability that can be improved by increasing its solubility and dissolution rate. The aim of this study is to enhance dissolution of Meclizine Hydrochloride as a model hydrophobic drug through application of inclusion complex technology. It was formulated as inclusion complex compact, and its dissolution property is evaluated and compared with marketed product of Meclizine Hcl tablet. The newly formulated drug and the interaction between excipients was examined by, Fourier-transform infrared spectroscopy, and differential s
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Matsushita, Masaki, Hiroshi Kitoh, Kenichi Mishima, et al. "Phase 1b study on the repurposing of meclizine hydrochloride for children with achondroplasia." PLOS ONE 18, no. 7 (2023): e0283425. http://dx.doi.org/10.1371/journal.pone.0283425.

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Achondroplasia (ACH) is a common skeletal dysplasia characterized by a disproportionately short stature. We found that meclizine, which is an over-the-counter drug for motion sickness, inhibited the fibroblast growth factor receptor 3 (FGFR3) gene using a drug repositioning strategy, and meclizine 1 and 2 mg/kg/day promoted bone growth in a mouse model of ACH. A previous phase 1a clinical trial for children with ACH demonstrated that a single dose of meclizine 25 and 50 mg was safe and that the simulated plasma concentration achieved steady state approximately 10 days after the first dose. The
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Singh, Harmandeep, Rupinder Kaur Sodhi, Simerjeet Kaur Chahal, and Jitender Madan. "Meclizine ameliorates memory deficits in streptozotocin-induced experimental dementia in mice: role of nuclear pregnane X receptors." Canadian Journal of Physiology and Pharmacology 98, no. 6 (2020): 383–90. http://dx.doi.org/10.1139/cjpp-2019-0421.

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Pregnane X receptors (PXRs) regulate the expression of ATP-binding cassette proteins transporters and organic anion transporting polypeptides responsible for influx/efflux of xenobiotics across the brain. Ligand activation of PXR augments the expression of P-gp and promotes amyloid-β clearance across the blood–brain barrier. Dementia was induced in mice by intacerebroventricular administration of streptozotocin (STZ) followed by treatment with meclizine, a PXR agonist, and subsequently exposed to the Morris water maze test and biochemical and histopathological analysis to evaluate the effect o
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Wiener, Guy, Anna Jamison, and Dror Tal. "Meclizine seasickness medication and its effect on central nervous system oxygen toxicity in a murine model." Diving and Hyperbaric Medicine Journal 54, no. 4 (2024): 296–300. https://doi.org/10.28920/dhm54.4.296-300.

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Introduction: Diving utilising closed circuit pure oxygen rebreather systems has become popular in professional settings. One of the hazards the oxygen diver faces is central nervous system oxygen toxicity (CNS-OT), causing potentially fatal convulsions. At the same time, divers frequently travel by boat, often suffering seasickness. The over-the-counter medication meclizine is an anticholinergic and antihistaminergic agent that has gained popularity in the treatment of seasickness. Reports have shown the inhibitory effect that acetylcholine has on glutamate, a main component in the mechanism
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Bhide, Prashant, and Reeshwa Nachinolkar. "FORMULATION DEVELOPMENT AND CHARACTERISATION OF MECLIZINE HYDROCHLORIDE FAST DISSOLVING TABLETS USING SOLID DISPERSION TECHNIQUE." International Journal of Applied Pharmaceutics 10, no. 4 (2018): 141. http://dx.doi.org/10.22159/ijap.2018v10i4.26493.

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Objective: The aim of the present investigation was to design and evaluate fast dissolving tablet (FDT) for the oral delivery containing solid dispersion of meclizine (MCZ) hydrochloride, an antiemetic drug.Methods: The solubility of meclizine was increased by preparing solid dispersions using mannitol as a carrier by fusion method. The prepared solid dispersion, was subjected for in vitro drug release, percent practical yield, drug content, infrared spectroscopy (IR), differential scanning calorimetry (DSC), scanning electron microscopy (SEM). Optimized solid dispersion was incorporated to pr
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Sri, A. Navya, K. Shiva Prasad, Hafsa Tahreem, et al. "A novel analytical method development and validation of estimation of meclizine HCL by UV spectroscopic method." International Journal of Multidisciplinary Research and Growth Evaluation 4, no. 3 (2023): 953–56. http://dx.doi.org/10.54660/.ijmrge.2023.4.3.953-956.

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A new simple, accurate, rapid, precise, reproducible and cost-effective spectrophotometric method for the quantitative estimation of Meclizine Hcl. The developed UV spectrophotometric method for the quantitative estimation of meclizine HCl is based on measurement of absorption at maxima wavelength 232nm using Methanol: DMF (40:60). The standard and sample solution were prepared by using Methanol: DMF as a solvent. Quantitative determination of the drug was performed at wavelength range 228-234nm.The linearity was established over the concentration range 5, 10, 15, 20, 25, µg/ml for the meclizi
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Kumar, Anubhav, Ashish Jain, Pradeep Kumar Yadav, and Akhlesh Kumar Singhai. "Development of Oro-Dispersible Tablet of Meclizine by Using Different Superdisintegrating Agents." Journal of Drug Delivery and Therapeutics 12, no. 4 (2022): 7–14. http://dx.doi.org/10.22270/jddt.v12i4.5413.

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The proposed study is development of oro-dispersible tablet containing meclizine hydrochloride solid dispersion (FMODDs) formulation with using natural superdisintegrant with direct compression. The superdisintegrants and its concentration shall be during the preparation of FMODDs with meclizine hydrochloride by using direct compression via employing different excipients in different ratio including: superdisintegrants {sodium starch glycolate (SSG), Ac-Di-Sol, crosspovidone (CP), Spray dried lactose and microcrystalline cellulose (MCC)} which were used alone and in various combination and man
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Al-Madhagi, Wafa M., Arwa Alshargabi, Abdulkarim K. Y. Alzomor, and Olla Sharhan. "Formulation of New Chewable Oral Dosage Forms of Meclizine and Pyridoxine Hydrochloride." Advances in Pharmacological and Pharmaceutical Sciences 2023 (July 29, 2023): 1–6. http://dx.doi.org/10.1155/2023/5512379.

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Nausea and vomiting are symptoms associated with a lot of diseases and oral tablets may be unprofitable for patients especially those suffering from nausea and vomiting. Therefore, this study aimed to formulate a new meclizine and pyridoxine combination formula for chewable tablets and provide rapid drug absorption and decrease motion sickness. The new chewable formulation has been prepared to provide fast action, is more acceptable, and could be used for all age categories. Seven trials haves been carried out to prepare to find the suitable one where formula 7 of the chewable gum preparation
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Dissertations / Theses on the topic "Meclizine"

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Lin, Jiunn-Chang, and 林俊昌. "Studies on the molecular mechanisms of Meclizine-induced cell cycle arrest and apoptosis in human colon adenocarcinoma cells." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/42542284287650953109.

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碩士<br>臺北醫學大學<br>醫學研究所<br>91<br>Meclizine, a kind of histamine H1 antagonist, has been used in the treatment of motion sickness and vertigo. In studying the interaction of drugs and cancer cell lines, we have found that meclizine dose-dependently induced apoptosis in COLO 205 cells. By DNA ladder assay, we demonstrated that DNA ladder appeared with meclizine treatment in COLO 205 cells if dosage larger than 50 μM. Besides, we observed that cell numbers decreased dose-dependently after treatment with meclizine in COLO 205 cells. By flow cytometry, we noticed that the percentage of COLO 205 cells
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Books on the topic "Meclizine"

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Parker, Philip M., and James N. Parker. Meclizine: A medical dictionary, bibliography, and annotated research guide to Internet references. ICON Health Publications, 2004.

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Blokdijk, G. J. Meclizine Hydrochloride; Complete Self-Assessment Guide. CreateSpace Independent Publishing Platform, 2018.

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Publications, ICON Health. Meclizine: A Medical Dictionary, Bibliography, And Annotated Research Guide To Internet References. Icon Health Publications, 2004.

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Book chapters on the topic "Meclizine"

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Papich, Mark G. "Meclizine." In Saunders Handbook of Veterinary Drugs. Elsevier, 2016. http://dx.doi.org/10.1016/b978-0-323-24485-5.00358-2.

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Tullberg, Sara. "Meclizine." In xPharm: The Comprehensive Pharmacology Reference. Elsevier, 2007. http://dx.doi.org/10.1016/b978-008055232-3.62112-9.

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Papich, Mark G. "Meclizine." In Papich Handbook of Veterinary Drugs. Elsevier, 2021. http://dx.doi.org/10.1016/b978-0-323-70957-6.00323-x.

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"Meclizine." In Hale’s Medications & Mothers’ Milk™ 2019. Springer Publishing Company, 2018. http://dx.doi.org/10.1891/9780826150356.0633.

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Brody, David L. "Dizziness." In Concussion Care Manual. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199383863.003.0014.

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Dizziness means many different things to different people: lightheadedness, vertigo, poor balance, mental fogginess, and others concerns. Lightheadedness, meaning a feeling like the patient may pass out, is usually due to low blood pressure, often orthostatic hypotension. Vertigo, meaning a sensation of spinning or movement, can be an inner ear problem or a brain problem: Stop toxic substances; if there is nystagmus, refer to ENT for a full evaluation; perform the Dix-Hallpike maneuver to assess for benign paroxysmal positional vertigo; and refer to physical therapy for repositioning maneuvers
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Brody, David L. "Dizziness." In Concussion Care Manual, edited by David L. Brody. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780190054793.003.0015.

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Dizziness means many different things to different people: lightheadedness, vertigo, poor balance, mental fogginess, and other concerns. Lightheadedness, meaning a feeling like the patient may pass out, is usually due to low blood pressure, often orthostatic hypotension. Vertigo, meaning a sensation of spinning or movement, can be an inner ear problem or a brain problem. Stop toxic substances; if there is nystagmus, refer to an ear, nose, and throat specialist (ENT) for a full evaluation. Perform the Dix Hallpike maneuvers to assess for benign paroxysmal positional vertigo and refer to physica
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Conference papers on the topic "Meclizine"

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Cui, Kaixi. "Predicting the Impact of CYP2D6 Genetic Polymorphisms on Meclizine Pharmacokinetics and Pharmacodynamics." In ICBET 2020: 2020 10th International Conference on Biomedical Engineering and Technology. ACM, 2020. http://dx.doi.org/10.1145/3397391.3397445.

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Teixeira, Sarah Fernandes, Ricardo Alexandre De Azevedo, Salomão Dória Jorge, Emer Suavinho Ferro, José Alexandre Marzagão Barbuto, and Adilson Kleber Ferreira. "Abstract B57: Meclizine synergistically enhances anticancer effects of paclitaxel in A549 lung cancer cells." In Abstracts: AACR International Conference held in cooperation with the Latin American Cooperative Oncology Group (LACOG) on Translational Cancer Medicine; May 4-6, 2017; São Paulo, Brazil. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1557-3265.tcm17-b57.

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Ghosh, S., N. Kedia Mehta, L. E. Gleeson, and J. Keane. "Meclizine Induces Aerobic Glycolysis in Human Macrophages and Can Enhance the Glycolytic Response to Mycobacterium Tuberculosis Infection." In American Thoracic Society 2024 International Conference, May 17-22, 2024 - San Diego, CA. American Thoracic Society, 2024. http://dx.doi.org/10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a4868.

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You might also be interested in the extended bibliographies on the topic 'Meclizine' for particular source types:
Journal articles
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