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Dissertations / Theses on the topic 'Medicinal Plants - drug effects'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

Müller, Adrienne Carmel. "African traditional medicine-antiretroviral interactions : effects of Sutherlandia frutescens on the pharmacokinetics of Atazanavir." Thesis, Rhodes University, 2011. http://hdl.handle.net/10962/d1013373.

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In response to the urgent call for investigations into antiretroviral (ARV)-African traditional medicine (ATM) interactions, this research was undertaken to ascertain whether chronic administration of the ATM, Sutherlandia frutescens (SF) may alter the bioavailability of the protease inhibitor (PI), atazanavir (ATV), which may impact on the safety or efficacy of the ARV. Prior to investigating a potential interaction between ATV and SF in vitro and in vivo, a high performance liquid chromatography method with ultraviolet detection (HPLC-UV) was developed and validated for the bioanalysis of AT

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2

Van, Gend Tania Anli. "Effect of a South African medicinal plant on antiretroviral drug induced abnormalities in rats." Thesis, Nelson Mandela Metropolitan University, 2008. http://hdl.handle.net/10948/1080.

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The worldwide AIDS epidemic is known to have had a profoundly negative social, economic and personal impact and has taken a heavy toll on existing health care systems, particularly in developing countries. South Africa is experiencing an HIV epidemic with enormous social and economic consequences. Lopinavir/ritonavir antiretroviral treatment has been accredited with having a significantly positive effect and is a key advance in controlling HIV morbidity and mortality. An indigenous South African medicinal plant, Sutherlandia frutescens, known for its anti-diabetic properties and immune-boostin

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3

Mukinda, James Tshikosa. "Acute and chronic toxicity of the flavonoid-containing plant, Artemisia afra in rodents." Thesis, University of the Western Cape, 2005. http://etd.uwc.ac.za/index.php?module=etd&amp.

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The aim of this study was to investigate the possible toxicity of the flavonoid-containing plant, Artemisia afra and especially establish the safety of the aqueous extract of this plant after acute and chronic administration to mice and rats respectively.

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4

Miyake, Mônica Aidar Menon. ""Efeitos da infusão de Luffa operculata sobre o epitélio e a atividade mucociliar do palato isolado de rã"." Universidade de São Paulo, 2004. http://www.teses.usp.br/teses/disponiveis/5/5143/tde-20102005-113139/.

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Luffa operculata é uma planta medicinal popularmente usada para tratamento de rinites e rinossinusites. A infusão de seu fruto seco é usada no nariz, liberando secreção mucosa profusa, mas pode causar irritação, epistaxe ou anosmia. Avaliamos os efeitos de diferentes concentrações da infusão do fruto seco da Luffa operculata na velocidade de transporte mucociliar (VTM), freqüência de batimento ciliar (FBC), diferença de potencial transepitelial (DPT) e morfologia do epitélio (microscopia de luz e eletrônica de transmissão), no modelo do palato isolado de rã. Os resultados apontam para dano epi

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5

Dias, Araujo Mazzari A. L. "In vitro effects of selected medicinal plants shortlisted for clinical use in the Brazilian public health system in CYP3A4 mRNA gene expression, glutathione levels and P-glycoprotein activity and their implications for herb-drug interactions." Thesis, University College London (University of London), 2017. http://discovery.ucl.ac.uk/1535229/.

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The Brazilian Unified Public Health System (SUS) shortlisted various plant species of interest (RENISUS) for future clinical use. However, very little is known about their effects on metabolic and transporter proteins, which could potentially lead to herb-drug interactions (HDI). To evaluate this, we conducted in vitro preclinical studies on twenty-four plant extracts to disclose their effects on CYP3A4 mRNA gene expression, intracellular glutathione (GSH) levels, inhibition of γ-glutamyl transferase (GGT) in HepG2 cells and P- glycoprotein (P-gp) activity in vincristine resistant Caco-2 (Caco

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6

Mogatle, Seloi. "African traditional medicines-antiretroviral drug interactions: the effect of African potato (Hypoxis hemerocallidea) on the pharmacokinetics of efavirenz in humans." Thesis, Rhodes University, 2009. http://hdl.handle.net/10962/d1003251.

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African Potato (Hypoxis hemerocallidea), (AP) is an African traditional medicine (TM) that is commonly used for various nutritional/medicinal purposes and also by people infected with the human immuno deficiency virus HIV and AIDS patients as an immune booster. The use of AP has also been recommended by the former Minister of Health of South Africa for use by HIV positive people. The main phytochemical component of AP is a norlignan glucoside, hypoxoside, and other relatively minor components have also been reported. A recent in vitro study reported the effects of AP extracts, hypoxoside and r

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7

Fontenele, Juvenia Bezerra. "Estudo farmacolÃgico da fraÃÃo hexÃnica de Lonchocarpus sericeus (Poir) Kunth e seus constituintes quÃmicos, lonchocarpina e derricina." Universidade Federal do CearÃ, 2004. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=33.

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FundaÃÃo de Amparo Ã Pesquisa do Estado do CearÃ<br>CoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel Superior<br>O gÃnero Lonchocarpus Ã bastante conhecido e amplamente estudado, porÃm nÃo hÃ registros na literatura cientÃfica dos usos farmacolÃgicos da espÃcie Lonchocarpus sericeus (Poir.) Kunth, (Leguminosae Papilionaceae). Estudos quÃmicos demonstraram que a fraÃÃo hexÃnica das cascas das raÃzes de L. sericeus (FLS) Ã rica nas chalconas: lonchocarpina (LCC) e derricina (DRC). O objetivo deste trabalho foi investigar os efeitos tÃxicos e as aÃÃes farmacolÃgicas da FLS e de sua chalconas LC

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8

Nkosi, Themba Johan. "Antimicrobial activities of three medicinal plants against selected diarrheagenic pathogens." Thesis, Nelson Mandela Metropolitan University, 2013. http://hdl.handle.net/10948/d1020759.

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Diarrhea is a global concern that the United Nations Children’s Fund (UNICEF) and the World Health Organization (WHO), have confirmed to be the second major cause of death in children under the age of five. Major bacterial pathogens that cause diarrhea include Escherichia coli, Salmonella species, Shigella species and Staphylococcus aureus. Antibiotic therapy is recommended depending on the severity and presentation of the disease; however, the appearance of antibiotic-resistant bacteria is an emerging global threat to the ability to treat these bacterial infections. This situation could be ov

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9

Khan, Fatima. "Effects of Leonotis leonorus aqueous extract on the isolated perfused rat heart." Thesis, University of the Western Cape, 2007. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_8367_1256897201.

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<p>&quot<br>An aqueous extract prepared from the leaves and smaller stems of Leonotis leonorus was used to investigate the potential effects on certain cardiovascular parameters such as left ventricular systonic pressure, end-diastolic pressure, developed pressure, heart rate, cardiac work and coronary perfusion pressure in isolated rat hearts...&quot<br></p>

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10

Mativandlela, Sannah Patience Nkami. "Antituberculosis activity of flavonoids Galenia africana L. var. africana." Pretoria : [s.n.], 2009. http://upetd.up.ac.za/thesis/available/etd-10172009-095531/.

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11

Suleiman, Khairunisa Yahya. "The effects of a Kenyan antidiabetic plant on insulin homeostasis." Thesis, Nelson Mandela Metropolitan University, 2009. http://hdl.handle.net/10948/1055.

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The metabolic disorder diabetes; is a global epidemic affecting people in developed countries and increasingly in developing countries. In two decades time, 350 million people will be diabetic at the current rate of prevalence. In a preliminary study, insulin resistant rats were treated with Prunus Africana (plant A) for 28 days. Plasma samples obtained from P. africana treated rats had increased insulin levels compared to normal and untreated insulin resistant rats (Karachi, 2009). The treatment of insulin resistant rats with P. africana also showed increased glucose uptake in rat adipose tis

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12

董穎 and Ying Dong. "Antitumor effects and mechanism of actions of Chinese herbalmedicines: a purified coriolus versicolorpeptide and tetrandrine." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1996. http://hub.hku.hk/bib/B31213066.

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13

Okpako, Larry Commander. "Investigation of selected Nigerian medicinal plants as a source of new antimalarial agents. Isolation of phytochemicals from some Nigerian medicinal plants using chromatographic techniques and their evaluation for antiplasmodial activity." Thesis, University of Bradford, 2012. http://hdl.handle.net/10454/6304.

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Malaria affects hundreds of millions of people worldwide and equally claims hundreds of thousands of lives each year. With the current spread of drug resistance to standard antimalarial drugs like chloroquine and the emergence of artemisinin-resistant parasites, new antimalarial drugs and formulations are urgently needed. An ethnobotanical survey was carried out in this study in search of novel compounds with promising antiplasmodial activity. Using the ethnobotanical approach, a total of 61 plant species from 59 genera distributed in 34 plant families were found to be used traditionally for

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14

Dong, Ying. "Antitumor effects and mechanism of actions of Chinese herbal medicines : a purified coriolus versicolor peptide and tetrandrine /." Hong Kong : University of Hong Kong, 1996. http://sunzi.lib.hku.hk/hkuto/record.jsp?B19669860.

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15

Ezuruike, U. F. "Evaluation of herb-drug interactions in Nigeria with a focus on medicinal plants used in diabetes management." Thesis, University College London (University of London), 2015. http://discovery.ucl.ac.uk/1465961/.

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Studies have shown an increasing use of herbal medicines alongside conventional drugs by patients in their disease management especially for chronic diseases, with the attendant risks of herb-drug interactions. In order to forestall this, adequate information about the pharmacological and toxicological profile of herbal medicines and how these would in turn affect the bioavailability of the co-administered drug is required. To evaluate potential herb-drug interactions that could occur in diabetes management in Nigeria- (a) An assessment of available data on the pharmacological and toxicologica

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16

Sibanda, Thulani. "Assessment of antibacterial potentials of Garcinia Kola seed extracts and their interactions with antibiotics." Thesis, University of Fort Hare, 2007. http://hdl.handle.net/10353/71.

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The antibacterial potency of the extracts of the seed of Garcinia kola (bitter kola) was investigated in this study against a panel of referenced, environmental and clinical bacterial strains. The killing rates of the active extract as well as their potential for combination antibacterial therapy with standard antibiotics were also elucidated using standard procedures. The aqueous and acetone extracts of the seed were screened for activity against 27 bacterial isolates. The aqueous extract exhibited activity mainly against Gram positive organisms with Minimum inhibitory concentration (MIC) val

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17

Aboyade, Oluwaseyi Mayode. "Effect of processing on the efficacy and safety of Solanum Aculeastrum Dunal berries." Thesis, University of Fort Hare, 2009. http://hdl.handle.net/10353/d1001051.

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General Abstract There has been a steady increase in the use of medicinal plants in the last two decades in both developed and developing countries for prevention, management and treatment of diseases. This increase has been due to reasons such as ease of access, better cultural acceptability and compatibility, cost effectiveness and also the bid to “go natural”. Unfortunately, the notion that herbal medicines are relatively safe because they are natural has led to serious and potentially fatal consequences in phytotherapy. The lack of rigorous research to prove the effectiveness and safety of

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18

Shen, Yi. "Identification of novel anticancer drug candidates from Chinese medicinal herbs with DNA replication-initiation proteins as the targets /." View abstract or full-text, 2008. http://library.ust.hk/cgi/db/thesis.pl?BICH%202008%20SHEN.

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19

Wang, Sheng Fang. "Neuroprotective effects and mechanisms of Traditional Chinese Medicinal compounds on experimental Parkinson disease models." Thesis, University of Macau, 2018. http://umaclib3.umac.mo/record=b3952179.

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20

Wu, Xia Xia. "The anti-inflammatory effects of two tanshinones isolated from Chinese herb Salvia miltiorrhiza Bunge." Thesis, University of Macau, 2018. http://umaclib3.umac.mo/record=b3952197.

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21

Purushothaman, Nair Vipin Devi Prasad. "Pharmaceutical analysis and drug interaction studies : African potato (Hypoxis hemerocallidea)." Thesis, Rhodes University, 2006. http://hdl.handle.net/10962/d1015802.

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In order for a medicinal product to produce a consistent and reliable therapeutic response, it is essential that the final composition of the product is invariable and that the active ingredient/s is/are present in appropriate, non-toxic amounts. However, due to the complexity involved in the standardization of natural products, quality control (QC) criteria and procedures for the registration and market approval of such products are conspicuously absent in most countries around the world. African Potato (AP) is of great medical interest and this particular plant has gained tremendous populari

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22

Ncise, Wanga. "Environmental stress effects on the phytochemistry and bioactivity responses of a South African medicinal bulbous plant, Tulbaghia violacea Harvey (Alliaceae)." Thesis, Cape Peninsula University of Technology, 2018. http://hdl.handle.net/20.500.11838/2854.

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Thesis (MTech (Horticulture))--Cape Peninsula University of Technology, 2018.<br>Deteriorating living and environmental conditions have contributed to the increasing prevalence of diseases in plants and animals. In humans, accumulation of abnormally high levels of free radicals in the tissues has been implicated in many non-communicable diseases, such as diabetes, cancer, arthritis, ischemia, gastritis, obesity and asthma. Worldwide, there is recognition of need to improve plant and animal health. Tulbaghia violacea (Alliaceae) is a medicinal plant that is extensively harvested by traditional

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23

Liang, Ye Er. "Hormetic effects induced by heat-clearing herb extracts attenuate anticancer activity of chemotherapeutic agents." Thesis, University of Macau, 2017. http://umaclib3.umac.mo/record=b3690847.

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24

Tsang, Hing Yan. "Anti-tumour and anti-angiogenic effects of euxanthone." HKBU Institutional Repository, 2001. http://repository.hkbu.edu.hk/etd_ra/363.

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25

Njume, Collise. "Phytochemical analysis and bioactivity of selected South African medicinal plants on clinical isolates of Helicobacter pylori." Thesis, University of Fort Hare, 2011. http://hdl.handle.net/10353/449.

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Medicinal plants have been used as traditional medicine in the treatment of numerous human diseases for thousands of years in many parts of the world. In the developing world, especially in rural areas, herbal remedies continue to be a primary source of medicine. Scientifically, medicinal plants have proven to be an abundant source of biologically active compounds, many of which have already been formulated into useful therapeutic substances or have provided a basis for the development of new lead molecules for pharmaceuticals. Antibiotic resistance, undesireable side effects and expences asso

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26

Belo, Cristóvão Ramiro. "Bétele (Piper Betle Linn): Análise de Metabolitos e acção sobre a Acetilcolinesterase." Dissertação, Faculdade de Farmácia da Universidade do Porto, 2009. http://hdl.handle.net/10216/20777.

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Mestrado em Controlo de Qualidade<br>MSc in Quality Control<br>Piper betle L., conhecida como bétele, é uma espécie que se desenvolve largamente nos países do Sudeste Asiático, onde as suas folhas são económica e medicinalmente importantes. Para determinar o maior número possível de compostos voláteis e semivoláteis, as folhas foram sujeitas as diferentes processos de extracção, nomeadamente headspace - microextracção em fase sólida (HS-SPME), hidrodestilação e extracção por Soxhlet, e posteriormente analisadas por GC/MS, o que permitiu identificar 50 compostos, distribuídos por várias classes

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Belo, Cristóvão Ramiro. "Bétele (Piper Betle Linn): Análise de Metabolitos e acção sobre a Acetilcolinesterase." Master's thesis, Faculdade de Farmácia da Universidade do Porto, 2009. http://hdl.handle.net/10216/20777.

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Mestrado em Controlo de Qualidade<br>MSc in Quality Control<br>Piper betle L., conhecida como bétele, é uma espécie que se desenvolve largamente nos países do Sudeste Asiático, onde as suas folhas são económica e medicinalmente importantes. Para determinar o maior número possível de compostos voláteis e semivoláteis, as folhas foram sujeitas as diferentes processos de extracção, nomeadamente headspace - microextracção em fase sólida (HS-SPME), hidrodestilação e extracção por Soxhlet, e posteriormente analisadas por GC/MS, o que permitiu identificar 50 compostos, distribuídos por várias classes

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28

Knowles, Cindy-Lee. "Synergistic effects of mixtures of the kresoxim-methyl fungicide and medicinal plants extracts in vitro and in vivo against Botrytis Cinerea." Thesis, University of the Western Cape, 2005. http://etd.uwc.ac.za/index.php?module=etd&amp.

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The fungus Botrytis cinerea is an opportunistic pathogen on a wide variety of crops, causing disease known as grey mould through infections via wounds or dead plant parts. Synthetic fungicides for controlling this disease are fast becoming ineffective due to the development of resistance. This, coupled with consumers world wide becomng increasingly conscious of potential environment and health problems associated with the build up of toxic chemicals, (particularly in food products), have resulted in pressure to reduce the use of chemical pesticide volumes as well as its residues. An emerging a

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Baatjies, Lucinda. "In vitro cytotoxic effects of selected Nigerian medicinal plant extracts on cancer cell lines." Thesis, Nelson Mandela Metropolitan University, 2012. http://hdl.handle.net/10948/d1008191.

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Cancer is a disease that imposes a heavy burden on public health and poses a challenge to science. The World Health Organization estimates that 80 percent of people in developing countries of the world rely on traditional medicine for their primary health needs, and about 85 percent of traditional medicine involves the use of plant extracts. This is particularly true in Africa where a large percentage of the population depends upon medicinal plants for health care. Therefore, detailed screening and evaluation of bioactive substances for chemotherapeutic purposes of African plants are urgently

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30

Wei, Wei. "Immunomodulating effects of natural polysaccharides isolated from astragali radix and dendrobii officinalis caulis /Wei Wei." HKBU Institutional Repository, 2016. https://repository.hkbu.edu.hk/etd_oa/350.

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Radix Astragali (the dried root of Astragalus membranaceous (Fisch) Bge.) and Dendrobii Officinalis Caulis (the dried stem of Dendrobium officinale Kimura et Migo) are two traditional Chinese tonic herbs. They are commonly used in the formula with other Chinese herbs for tonifying Qi, nourishing Yin, and treating various kinds of diseases, such as cancer, diabetes, inflammation, etc. The polysaccharides are considered the majority of the chemical components of decoction boiled from a formula including these two medicinal herbs. The previous study showed that the polysaccharides isolated from R

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31

Penduka, Dambudzo. "In-vitro anti-vibrio activities of crude extracts of Garcinia Kola seeds." Thesis, University of Fort Hare, 2011. http://hdl.handle.net/10353/405.

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The n-Hexane, dichloromethane, methanol and aqueous crude extracts of Garcinia kola (Heckel) seeds were screened for their anti-Vibrio activities against 50 Vibrio bacteria isolated from wastewater final effluents. The 50 isolates consisted of different Vibrio species namely V. fluvialis (14), V. vulnificus (12), V. parahaemolyticus (12), V. metschnikovii (3) and 9 others unidentified to the specie level. The n-Hexane, dichloromethane and methanol extracts had activities against 16 (32 percent) of the Vibrio isolates, while the aqueous extracts had activities against 12 (24 percent) all at a s

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Qodi, Noluntu. "In Vitro tests for immunomodulatory effects of medicinal plants used in the treatment of Malaria in South Africa." Master's thesis, University of Cape Town, 2001. http://hdl.handle.net/11427/3454.

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Bibliography: leaves 78-80.<br>Using the ethno-medicinal data approach, nine South African plants used traditionally in the treatment of malaria were collected and evaluated for cytotoxic and lymphocyte-proliferating effects. These included Acokanthera oppositofolia, Zanthoxylum capense, Glycyrrhiza glabra, Harpephyllum caffrum, Lippia javanica, Pentanisia prunneloides, Psidium guajava, Typha capensis and Cannabis sativa. The cytotoxic effect of the aqueous, methanol and dichloromethane extracts of these plants was evaluated in vitro in Rat-1 fibroblasts there was no observable difference in c

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Shauli, Mathulo Mathabiso. "Histopathology induced by a medicinal plant indigenous to South Africa that has shown in vitro anti-microbial activity against drug resistant strains of Mycobacterium tuberculosis." Thesis, Nelson Mandela Metropolitan University, 2015. http://hdl.handle.net/10948/3990.

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Tuberculosis (TB) still remains a health problem globally with over a million new infections and a mortality rate of 1.5 million individuals annually (Hawn et al., 2014). The emerging multi-drug resistant (MDR) strains that accompany human immune deficiency virus (HIV) infection in high-incidence populations contribute significantly to the health burden of TB (Areeshi et al., 2014). The standard treatment that is advocated by the World Health Organization (WHO) for active tuberculosis includes long-term therapy that incorporates the use of isoniazid, rifampicin, pyrazinimide and ethambutol as

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Wei, Xi. "Effects of residual veterinary antibiotics on soil enzyme activity and plant growth." HKBU Institutional Repository, 2007. http://repository.hkbu.edu.hk/etd_ra/830.

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Chadwick, Wayne. "Metabolic effects brought about by tricyclic antidepressants and the contribution of a medicinal plant in alleviating high fat diet induced insulin resistance in male wistar rats." Thesis, Nelson Mandela Metropolitan University, 2006. http://hdl.handle.net/10948/461.

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Type II diabetes is becoming a growing problem in developed countries worldwide. The median age for diagnosis was around sixty, but recent surveys have shown that the entire age distribution curve shifting left. The incidence of type II diabetes is thought to be parallel with the growing rate of obesity associated with an unhealthy western diet. Type II diabetes is an expensive disease to manage, it is for this reason that cheaper medication needs to be investigated in the form of traditional plants, such as Sutherlandia frutescens. Prescription medication, such as tricyclic antidepressants, m

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Hikuam, Willem Christoph. "Modulation of the redox status, phase 2 drug metabolizing enzymes and fumonisin-induced cancer promotion in rat liver by selected Southern African medicinal plants." Thesis, Cape Peninsula University of Technology, 2014. http://hdl.handle.net/20.500.11838/1524.

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Thesis submitted in fulfilment of the requirements for the degree Doctor of Technology: Biomedical Technology in the Faculty of Health and Wellness Sciences at the Cape Peninsula University of Technology 2014<br>According to the World Health Organization, cancer is the leading cause of death in the developed world, while it is the second leading cause of death in the developing world. In particular, liver cancer is the fifth most commonly diagnosed cancer in men, however, it is the second most frequent cause of death, responsible for an estimated 700,000 deaths annually. General limited access

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Elgenaidi, Abdalla Ramadan. "Effects of Libyan traditional plants on the reproductive system of male and female rats." University of the Western cape, 2015. http://hdl.handle.net/11394/5412.

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Philosophiae Doctor - PhD<br>In different parts of the world, medicinal plants have demonstrated a lot of health benefits to mankind and remains an important source for the discovery of new bio-active compounds. Libya is a typical example of a country where medicinal plants are widely used. Plant extracts of five Libyan medicinal plants were used in this study to investigate their in vivo effects on spermatogenesis and steroidogenesis in male rats and on ovulation and fertility in female rats. The In vitro effects of these plant extracts were also investigated on TM3 Leydig cells and MCF 7 bre

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Tyavambiza, Caroline. "The antimicrobial and immunomodulatory effects of Cotyledon Orbiculata extracts." Thesis, Cape Peninsula University of Technology, 2018. http://hdl.handle.net/20.500.11838/2721.

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Thesis (MSc (Biomedical Technology))--Cape Peninsula University of Technology, 2018.<br>The challenge of antimicrobial resistance has increased drastically over the years as more microorganisms are becoming resistant to the available conventional treatments. The burden of antimicrobial resistant infections is intensified by the increase in immunocompromising conditions such as HIV/AIDS and cancer. Due to this challenge, pharmaceutical companies, health sectors and researches are in search of new antimicrobial agents that can solve the problem at hand. Medicinal plants are a reliable source for

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Owen, Josée. "The effects of nitrogen, harvest method and substrate on the growth and the medicinal compound concentration of hydroponically-grown sundew (Drosera adelae F. Muell.) /." Thesis, McGill University, 2000. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=33435.

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Some species of sundew (Drosera spp.), harvested from the wild for use in homeopathic cold remedies, are now endangered. This research consisted of two experiments in hydroponic production of sundew. The first investigated the effects of four nitrogen (N) fertilization levels (0.0, 5.1, 25.5 or 51.0 mg/L added N) and three harvest methods (after two months, four months, and sequential harvest at two and four months) on the growth of Drosera adelae (F. Muell.). In addition, the effect of N on the production of a medicinal active ingredient in D. adelae was examined. The second experiment invest

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Ajayi, Emmanuel Olusegun. "Interaction of terpenes and oxygenated terpenes with some drugs." Thesis, University of Fort Hare, 2012. http://hdl.handle.net/10353/418.

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SFME and HD for the extraction of essential oil in Lavandula officinalis in Alice have been reported. A total of 59 compounds were identified with the major compound being 1,8-cineole, an oxygenated monoterpene, with 46.89% and 44.84% yield obtained for HD and SFME respectively. Charge transfer (CT) complexes formed between α-pinene, 1,8-cineole and camphor as electron donors with iodine as the electron acceptor have been studied spectrophotometrically in methylene chloride solution. The Benesi- Hildebrand equation has been applied to estimate the formation constant (Kf) and molecular extincti

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Davison, Candice. "A biochemical study of the antidiabetic and anticogulant effects of Tulbaghia Violacea." Thesis, Nelson Mandela Metropolitan University, 2010. http://hdl.handle.net/10948/1523.

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Secondary metabolites derived from plants, especially those used by traditional healers, are at the forefront of new drug development in combating diseases such as cancer and diabetes. Garlic is employed in indigenous medicine all over the world for the treatment of a variety of diseases. Dietary garlic has been recognized for its beneficial health effects. In particular, garlic consumption has been correlated with (i) reduction of risk factors for cardiovascular diseases and cancer, (ii) stimulation of immune function, (iii) enhanced detoxification of foreign compounds, (iv) hepatoprotection,

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Amare, Ayalew Mamed. "Mycoflora and mycotoxins of major cereal grains and antifungal effects of selected medical plants from Ethiopia /." Göttingen : Cuvillier, 2002. http://www.loc.gov/catdir/toc/fy0612/2006388754.html.

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Omodanisi, Elizabeth Ife. "Modulatory effects of Moringa oleifera extracts on Streptozotocin-induced diabetes in male Wistar rats." Thesis, Cape Peninsula University of Technology, 2017. http://hdl.handle.net/20.500.11838/2558.

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Thesis (DTech (Biomedical Technology))--Cape Peninsula University of Technology, 2017.<br>Diabetes mellitus (DM) is characterized by deficiency in insulin resulting in hyperglycaemia with metabolic alterations in carbohydrate, lipid and protein. DM has been associated with increased formation of reactive oxygen species (ROS) and inflammatory mediators. Many drugs have been designed for its treatment and management; however, limitations persist in the use of anti-hyperglycemic medications due to numerous side effects, high cost, limited action and secondary failure rates. Moringa oleifera (MO)

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Jin, Jing, and 金晶. "Proteomic profiling of mycelial extract derived from coriolus versicolor and analysis of their anti-tumor effects in human leukemiccells HL-60." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B41897110.

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"Study on the liver protective effects of Schisandra chinensis." 1999. http://library.cuhk.edu.hk/record=b5889971.

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by King Yeung Wong.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 1999.<br>Includes bibliographical references (leaves 143-148).<br>Abstracts in English and Chinese.<br>Title Page --- p.i<br>Acknowledgement --- p.ii<br>List of Abbreviations --- p.iii<br>Table of contents --- p.v<br>Abstract --- p.viii<br>Chapter 1 --- Introduction --- p.1<br>Chapter 1.1 --- Liver diseases --- p.1<br>Chapter 1.2 --- Current treatments of liver diseases --- p.3<br>Chapter 1.3 --- Schizandrae --- p.5<br>Chapter 1.3.1 --- Chemistry of Schizandrae (Wuweizi) --- p.6<br>Chapter 1.3.2 --- Pharmacolog

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Dangarembizi, Rachael. "Effects of crude leaf extracts of Ficus thonningii on growth, gastrointestinal morphometrry and clinical biochemistry of suckling Sprague Dawley rats." Thesis, 2014.

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Ficus thonningii is a nutraceutical that is extensively used in ethnomedicine. Nursing mothers use F. thonningii leaves as nutritional and medicinal supplements and are at risk of exposing their infants to its constituent phytochemicals. The exposure of the sensitive neonatal gastrointestinal tract (GIT) to these phytochemicals can result in irreversible changes in growth and development. The objectives of this study were to determine the effects of crude F. thonningii extracts on; growth, morphology and morphometry of the abdominal viscera and clinical biochemistry of neonatal rats. Fo

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"In vitro and in vivo studies on the wound healing effects of Chinese medicinal herbs." 2007. http://library.cuhk.edu.hk/record=b5893193.

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Law, Wai Tak.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2007.<br>Includes bibliographical references (leaves 107-123).<br>Abstracts in English and Chinese.<br>Abstract --- p.i<br>摘要 --- p.iv<br>Acknowledgements --- p.vi<br>Publications --- p.viii<br>Table of Contents --- p.ix<br>Chapter Chapter 1 --- Introduction<br>Chapter 1.1 --- Wound healing --- p.1<br>Chapter 1.1.1 --- Physiology of wound healing --- p.1<br>Chapter 1.1.2 --- Three phases of wound healing --- p.3<br>Chapter 1.1.3 --- Angiogenesis in wound healing --- p.10<br>Chapter 1.2 --- Delayed wound healing --- p

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Street, Renée Anne. "Heavy metals in South African medicinal plants." Thesis, 2008. http://hdl.handle.net/10413/801.

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Plants are able to take up and accumulate certain environmental contaminants such as heavy metals. When the plants are ingested by man, these contaminants are transferred along the food chain. Due to the poorly regulated medicinal plant trade in South Africa, many opportunities exist for heavy metal contamination of medicinal plants namely contaminated harvest sites as well as poor drying, processing, storage, transport and manufacturing conditions. The concentrations of five heavy metals (As, Cd, Co, Ni, Pb) and six microelements (B, Cu, Fe, Mn, Mo, Zn) were determined in some commonly used S

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"Identification, purification and biological studies of the lead compound from Chinese herbs for the reactivation of fetal hemoglobin expression." 2003. http://library.cuhk.edu.hk/record=b6073529.

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Xing Hongtao.<br>"February 2003."<br>Thesis (Ph.D.)--Chinese University of Hong Kong, 2003.<br>Includes bibliographical references (p. 149-176).<br>Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web.<br>Electronic reproduction. Ann Arbor, MI : ProQuest Information and Learning Company, [200-] System requirements: Adobe Acrobat Reader. Available via World Wide Web.<br>Mode of access: World Wide Web.<br>Abstracts in English and Chinese.

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"Immunomodulatory effects and toxicity of mimosa pudica, the sensitive plant." Chinese University of Hong Kong, 1993. http://library.cuhk.edu.hk/record=b5887741.

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by Cheng Yuk Kwan, Anna.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 1993.<br>Includes bibliographical references (leaves 104-112).<br>Acknowledgements<br>Table of Contents --- p.i<br>Abbreviations --- p.iv<br>Abstract --- p.vi<br>List of figures --- p.ix<br>List of tables --- p.xi<br>Chapter Chapter One: --- Introduction<br>Chapter 1.1 --- Objective and scope of the project --- p.1<br>Chapter 1.2 --- Literature review of Mimosa pudica<br>Chapter 1.2.1 --- Morphology of Mimosa pudica --- p.3<br>Chapter 1.2.2 --- Chemistry of Mimosa pudica --- p.5<br>Chapter 1.2.3 --- Uses in

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