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Relevant bibliographies by topics / Mefenamic acid (MFA)

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Journal articles

Academic literature on the topic 'Mefenamic acid (MFA)'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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Journal articles on the topic "Mefenamic acid (MFA)"

1

Hoque, Md Aminul, Anan Mahabub Aboni, Tasbira Jasmeen, and Sherejad Sanam. "Infrared Spectroscopic Study of Binding Interaction of Metal Complexes with Mefenamic Acid (MFA)." Journal of Pharmaceutical Research International 35, no. 2 (2023): 30–40. http://dx.doi.org/10.9734/jpri/2023/v35i27313.

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Aims: The foremost aim of this study was to evaluate the 1:1 formed complex when mefenamic acid interacts with Cu2+, Zn2+, and EDTA4- metal at the physiological condition, which provides a better understanding of the pharmacological studies. This research provided information on the binding affinity of mefenamic acid with selective metals. It helps with preparative, structural, and reactivity studies for multiple drug designs in pharmaceutical fields. Place and Duration of Study: Department of Pharmacy, Stamford University Bangladesh, Dhaka, Bangladesh & CARS ((Centre for Advanced Re

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2

Yamazaki, Moe, Emi Shimamura, Takehisa Hanawa, and Yayoi Kawano. "Microparticulated Mefenamic Acid with High Dispersion Stability for Pediatric Dosage Form." Children 9, no. 6 (2022): 861. http://dx.doi.org/10.3390/children9060861.

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Mefenamic acid (MFA), a water-insoluble drug, is used as a suspension in the medical field, but it requires shaking before using to disperse MFA content in the suspension. In previous studies, trials to prepare MFA suspension with high dispersion stability by atomizing MFA by the wet-milling method. However, HPC is used for atomizing MFA. Therefore, the optimum concentration and molecular weight for atomizing MFA have not been investigated. In this study, we investigated the optimum molecular weight and concentration of HPC for the micronization of MFA. As a result, MFA particles became fine p

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3

Purwantoro, Dwi Utami, Ilma Nugrahani, and Slamet Ibrahim Surantaatmadja. "Studies of preparation, characterization, and solubility of mefenamic acid-nicotinamide co-crystal synthesized by using melt crystallization method." Asian Journal of Pharmaceutical and Clinical Research 10, no. 5 (2017): 135. http://dx.doi.org/10.22159/ajpcr.2017.v10i5.15863.

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Objective : The objective of this study is to develop the formation mefenamic acid (MFA) – nicotinamide (NCT) co-crystal by using melt crystallization method and investigate its solubility.Method : Co-crystal was prepared by using melt crystallization method of MFA-NCT (1:2) at (220±3) ° C. The initial co-crystal formation was performed by powder x-ray diffraction (PXRD). The thin layer chromatography (TLC) method was done to confirm the chemical stability of MFA and NCT due to synthesized process. The melt crystallization of MFA-NCT (1:2) was characterized by DSC/TG, Infrared spectrophotometr

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4

Dehghan, Tezerjani, Ali Benvidi, Masoud Rezaeinasab, Shahriar Jahanbani, and Ardakani Mazloum. "A nanostructured suitable platform based on multi wall carbon nanotubes and graphene nano sheets composite for determination of mefenamic acid." Journal of the Serbian Chemical Society 82, no. 11 (2017): 1273–86. http://dx.doi.org/10.2298/jsc161217043d.

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A mefenamic acid sensor was prepared by the modification of a glassy carbon electrode (GCE) with graphene nano-sheets (Gr) and multi wall carbon nanotubes (MWCNT). The designed sensor (MWCNT/Gr/GCE) indicated an electrocatalytic behaviour when applied for mefenamic acid (MFA) oxidation due to good conductivity, low electron transfer resistance and catalytic effect. The suggested sensor revealed a lower overvoltage and enhanced current compared with bare GCE for the oxidation of MFA. The observations indicated that the oxidation potential of MFA is decreased more than 200 mV using the designed

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5

Bukkitgar, S. D., N. P. Shetti, R. M. Kulkarni, and S. T. Nandibewoor. "Electro-sensing base for mefenamic acid on a 5% barium-doped zinc oxide nanoparticle modified electrode and its analytical application." RSC Advances 5, no. 127 (2015): 104891–99. http://dx.doi.org/10.1039/c5ra22581g.

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6

Lee, Wonseok, Yewon Mun, Kang-Yo Lee, et al. "Mefenamic Acid-Upregulated Nrf2/SQSTM1 Protects Hepatocytes against Oxidative Stress-Induced Cell Damage." Toxics 11, no. 9 (2023): 735. http://dx.doi.org/10.3390/toxics11090735.

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Mefenamic acid (MFA) is a commonly prescribed non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory and analgesic properties. MFA is known to have potent antioxidant properties and a neuroprotective effect against oxidative stress. However, its impact on the liver is unclear. This study aimed to elucidate the antioxidative effects of MFA and their underlying mechanisms. We observed that MFA treatment upregulated the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway. Treatment with various anthranilic acid derivative-class NSAIDs, including MFA, increased the expression o

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7

Ari Wahyudi, Dwi Utami, and Arif Budi Setianto. "The crystal packing and slip plane analysis in mechanical properties improvement of mefenamic acid by cocrystallization with nicotinamide coformer." Communications in Science and Technology 5, no. 2 (2020): 93–97. http://dx.doi.org/10.21924/cst.5.2.2020.213.

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Mefenamic acid is an analgesic non-steroidal anti-inflammatory drug (NSAID) that is categorized as Biopharmaceutical Classification System (BCS) class II drug. Cocrystallization of mefenamic acid (MFA) with nicotinamide (NIC) has been reported to enhance the solubility of MFA for about 2.56 times higher than pure MFA. As a part of MFA-NIC development in pharmaceutical dosage form, we reported the improvement of mechanical properties of MFA-NIC cocrystal based on the presence of slip planes in crystal structure. The research was initially by synthesizing and characterizing the cocrystal by usin

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8

Nakka, Srinivas, Naresh Kumar Katari, Siva Krishna Muchakayala, Sreekantha Babu Jonnalagadda, and Surendra Babu Manabolu Surya. "A novel LC-TQ-MS/MS method for quantifying mefenamic acid-NDSRI (N-nitroso drug substance-related impurity) in mefenamic acid tablet and pediatric suspension dosage forms: a comparative study with a cost-effective white, green, and blue UPLC method." RSC Advances 15, no. 3 (2025): 1957–69. https://doi.org/10.1039/d4ra08425j.

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The current research presents novel LC-TQ-MS/MS and cost-effective UPLC methods intended for the accurate quantification of NDSRI impurities in mefenamic acid (MFA) tablet and pediatric suspension dosage forms.

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9

Hammood, Mohammad K., and Maryam Hamed. "Simultaneous Determination of Trace Mefenamic Acid in Pharmaceutical Samples via Flow Injection Fluorometry." International Journal of Drug Delivery Technology 10, no. 03 (2020): 395–401. http://dx.doi.org/10.25258/ijddt.10.3.16.

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Mefenamic acid belongs to non-steroidal anti-inflammatory drugs that are used widely for the treatment of analgesia. Our aim from this study is to establish a new assay for the quantitative determination of mefenamic acid (MFA) in the pharmaceutical sample by two sensitive and rapid flow injection-fluorometric methods. A homemade fluorometer was used in fluorescence measurements, which using solid-state laser diode 405 and 532 nm as a source, combined with a continuous flow injection technique. The first method depends on the effect of MFA on calcein blue (CLB) fluorescence at 405 nm. Another

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10

Sayyed Mudasar Hussain, Uzair Nisar, Kalpana Jeewnani, Muhammad Jamal, Shabana Usman Simjee, and Umbreen Farrukh. "Protective Effects of Mefenamic Acid against Pentylenetetrazol-Induced Seizures: An Experimental Study." RADS Journal of Pharmacy and Allied Health Sciences 2, no. 2 (2024): 19–26. https://doi.org/10.37962/jphs.v2i2.114.

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Background: Epilepsy is a chronic neurological disorder characterized by recurrent seizures due to abnormal electrical activity in the brain. Despite advancements in treatment, approximately 30% of patients remain unresponsive to current antiepileptic drugs (AEDs), highlighting the need for alternative therapies. Mefenamic acid (MFA), a nonsteroidal anti-inflammatory drug (NSAID), has shown potential anticonvulsant properties, possibly through modulation of GABAA receptors and adenosine signaling. Objective: This study aimed to evaluate the anticonvulsant effects of MFA in a pentylenetetrazol

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